LOCUS       NZ_FNHE01000002        22102 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Geodermatophilus siccatus strain DSM 45419, whole genome shotgun
            sequence.
ACCESSION   NZ_FNHE01000002
VERSION     NZ_FNHE01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Geodermatophilus siccatus
  ORGANISM  Geodermatophilus siccatus
            Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
            Geodermatophilaceae; Geodermatophilus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900103785.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:00:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,951
            CDSs (total)                      :: 4,891
            Genes (coding)                    :: 4,846
            CDSs (with protein)               :: 4,846
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 11 of 45
            Pseudo Genes (incomplete)         :: 37 of 45
            Pseudo Genes (internal stop)      :: 5 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:54:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 457067
            Orig. end                         :: 479169
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNHE01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22102
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="3"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22102
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22102
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12102](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12102)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    222..236
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            966..1703
                     /locus_tag="BLS21_RS05340"
                     /old_locus_tag="SAMN05660642_01079"
     CDS             966..1703
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014740048.1"
                     /locus_tag="BLS21_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01079"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_091214777.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.1e-19, bitscore:
                     64.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEATANGARPTVALVHGAFADSAGWTDVVARLLADRVRVRAVSN
                     PLRGIAHDAAYVASALSQIDGPVLAVGHSYGGAVITNAALRAGNVVGLVYVAGFAPDEG
                     ETLQDVEADSRDSVLLTALLQWSYPTADGGTETEFAIDPDRFHDAFAADVPEEQSRVMA
                     ATQRPVSALAFGEPTTAPAWKDLPSWAVVPTGDKAVGSDVLRTMAARAGATVTEVEGSH
                     VIMISRPEVVTEVVRQALRAVPA"
     gene            complement(1768..2064)
                     /locus_tag="BLS21_RS05345"
                     /old_locus_tag="SAMN05660642_01080"
     CDS             complement(1768..2064)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040451.3"
                     /locus_tag="BLS21_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01080"
                     /product="DUF6510 family protein"
                     /protein_id="WP_072913449.1"
                     /transl_table=11
                     /translation="MTGVPETGDRRLDGNAAGGVLREVFAVDPTTAVSTCAHCGRPAPL
                     GEHLVYADAPALVVRCPGCMQVVLRCASDAAGLRLEMTGVRLLRMTPAEGASG"
     gene            complement(2098..2571)
                     /locus_tag="BLS21_RS05350"
                     /old_locus_tag="SAMN05660642_01081"
     CDS             complement(2098..2571)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082285.1"
                     /locus_tag="BLS21_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01081"
                     /product="DUF5709 domain-containing protein"
                     /protein_id="WP_091214780.1"
                     /transl_table=11
                     /translation="MDPFVFGTDGTDPEEDSGVLEPQDTLEDLGGVTDVLDTGWSPAER
                     PWAVTDWGTTEREELAGESLAGRLAREVPEQQQVEGDGLGDASDTDGELIDDEVGGRRA
                     GRLVETAERWGDVEPELYALDVGIDSGAASAEEGAVHVVPDEDDAWSPGWTDR"
     misc_feature    complement(2738..2756)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.05"
                     /tool="antismash"
     gene            2841..5654
                     /locus_tag="BLS21_RS05355"
                     /old_locus_tag="SAMN05660642_01082"
     CDS             2841..5654
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="BLS21_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01082"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_091214783.1"
                     /transl_table=11
                     /translation="MPEALAPVRTADAGLIGRSAECAALASFLDRALSTGAVLLVTGEP
                     GVGKTLLLETAARDAAASGATVVHAAGVEFEAEVGFAGLNQLLLPLLDDLETLPEPHRE
                     ALVVALGLGAGPPSHRLLVSAAVLGLLTRAAESRPVLVVVDDVPWVDRPSERVLGFVAR
                     RLDRSRIGLIAAARTGSDCVLLQAGLPQLEVPPLGEDAATELLRARFPVLDAQIRRRVL
                     EASQGNPLALLELPAVMTEAQRTGSDPLPSALPLSSHLQRVFAQQLAALPERTRELLLL
                     AALEGTGDLRTLRAAAATDGWLDDLAPAERARLLRIDLAAGRVTLRHPLIGSAAVQLST
                     SGELRRAHGALAHVLVDRPEECAWHLAEAVVGADARAADLLETAAHRARHKGDAVHAVN
                     ALLRAADLTPSGPDRARRLAAAAFVGADTTGDLRNVPQLLSAARTADPRTAGSLEVAVA
                     AAHHLLNGEGDVETAHRMLVRAVEYALDHGSGAATVEDALHSLMLVCHFGGRDELWRPF
                     EWALEALGPDLPPVLSVSRTVFADPVRAAPAALERLDELIVSAHTGVDPTHVVRVGMAA
                     LYADRLSGCRQALRRVVRDGRQGGAAASAVNALMLLCHDAFDGGRWQEAGRTAEEGRAW
                     GEELGYRLITLSGVYCSALLAAARGDDGTAETLADELVTWSAPRAVRLLEDFAHRVRGL
                     AALGRGNFEDAYRELSAVSQPGGFAPYAPVGLTVAMDLVEAAVRTGRRPEAAAHVAAME
                     RAPIFTGRPKLALVKAGSAALVAPGEEASRRFEEALAVPGAEQYPFERARVQLAYGEHL
                     RRSRATNASRVQLTAALERFRQLGARPWATRAANEVRATGLTHRGATGDRGAGALTAQE
                     HQIAMLAASGLSNKQIGSRLYLSPRTVGAHLYRVFPKLGITSRAALRDALSGTAREAAA
                     EAAAVVL"
     gene            5723..6325
                     /locus_tag="BLS21_RS05360"
                     /old_locus_tag="SAMN05660642_01083"
     CDS             5723..6325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662028.1"
                     /locus_tag="BLS21_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01083"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_091214786.1"
                     /transl_table=11
                     /translation="MSLVSRGFGRREQRRDERLPPGQYDAGDLFPVLSAGPTPRTPLGE
                     WDLTLQGEVDGLRRWTWDEFRELPREAVSVDIHCVTKWSKFDTRWEGVAVDTLLAGVRT
                     EAAYALAFCDGGYTTNHRLSDLTDGRAWVVDTYDGQPLAPEHGGPVRLLVPHLYFWKSA
                     KWLRGFALSQFNEPGFWETFGYHDRGDPWLEQRYSGD"
     gene            6295..7056
                     /locus_tag="BLS21_RS05365"
                     /old_locus_tag="SAMN05660642_01084"
     CDS             6295..7056
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014739164.1"
                     /locus_tag="BLS21_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01084"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_091214789.1"
                     /transl_table=11
                     /translation="MARAAVQRRLNWLRATVLENRPETARVHRLLLDVPGWPGHLPGQH
                     VDLRLTAEDGYTAQRSYSVASAPEDPRLHLLVERFEGGEVSPYLTDELRSGDLLELRGP
                     IGGYFVWSSAVDRDGGRAEGRRPVQLVAGGAGVAPFLAMLDHHRRTGGSTPVRLLYSAR
                     TADDVLAPDVLGPQTTITLTREAPSDWRGLTGRIDRRMLEAQTFAPTTRPRVFVCGPTS
                     FVESTATTLVDLGHDPSWIRLERFGGSGDPS"
     gene            7068..7772
                     /locus_tag="BLS21_RS05370"
                     /old_locus_tag="SAMN05660642_01085"
     CDS             7068..7772
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS21_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05660642_01085"
                     /product="hypothetical protein"
                     /protein_id="WP_091214792.1"
                     /transl_table=11
                     /translation="MSVRSRVLAVAAATTTVVGTGTVAMPPASAATPACGPGCIAVFSP
                     EFGTHGDPQFVEAVLDGVGTVGQPLVLQRAGSSDPSQDFLPRGGLVSDFFATGMVSAAV
                     NGHYGSLRAAQLEYAPSGVASGLCVGLAGTAYEDEPLGLQPCSVPGTTVWIVDTADSPA
                     TAADGYSPLVNGSTTDVTHPLAMTYPADAAPTDEPAPQIHVSRLHSCGHADPAGRAVPD
                     RQLWGTVLGVLE"
     gene            7960..8373
                     /locus_tag="BLS21_RS05375"
                     /old_locus_tag="SAMN05660642_01086"
     CDS             7960..8373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948565.1"
                     /locus_tag="BLS21_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01086"
                     /product="heme-binding protein"
                     /protein_id="WP_091214796.1"
                     /transl_table=11
                     /translation="MTQQLTTLTLDDARRIVAAGEARAAEIGQPMNIAVVDAGGDLVMH
                     VRMDGAWRGSVDIAINKAFTARAFDIATAELADLAKPGGPFYGIQASNNGKVMVFAGGA
                     PVLVDGVVVGAVGVSGGTGEQDTTVCEAATAGL"
     gene            complement(8384..8791)
                     /locus_tag="BLS21_RS05380"
                     /old_locus_tag="SAMN05660642_01087"
     CDS             complement(8384..8791)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948564.1"
                     /locus_tag="BLS21_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01087"
                     /product="YkvA family protein"
                     /protein_id="WP_091214799.1"
                     /transl_table=11
                     /translation="MPDWAWTLVGVLGGLLLCWLVLMAVLWATRPDDLRLRELLRLLPD
                     VLRLVHRLAGDGTLPRGVRVRLWLLLGYLALPFDLVPDFVPVLGHADDAIVVALVLRSV
                     VRHAGAAALDRHWPGTPDGLAALRRAGRLPA"
     gene            complement(8851..9948)
                     /locus_tag="BLS21_RS05385"
                     /old_locus_tag="SAMN05660642_01088"
     CDS             complement(8851..9948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948563.1"
                     /locus_tag="BLS21_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01088"
                     /product="sodium:proton exchanger"
                     /protein_id="WP_091214802.1"
                     /transl_table=11
                     /translation="MTSVFVFISGATLLVVSAEKLITHLVGAASGLRIPLFLLAVVFTG
                     VEFDDIALGVGLNLEDLSGVALGVVFGTALSFTGVVLAVAAVIRPSQVAIPRDYLVLFA
                     AAPLVMVAVTLAGPLTVTDGLLLLGLFVLFVTYVAARELRRSVAVFRDVEVYEAAVAEA
                     GDDVPSLRAAGTDVRPAPAVGAGARAGAERTQQVVEEAPRTDERDLPGWAHLGLAVVAL
                     AGLVVGAATVSTGTEGILAAYGLEGTVFGATIATAVLTMEDVFLTVEPFRRGVPEIGVG
                     NVIGSVVFSVTGKLGITLLAGGIVVGRDVFTWHLPALVVLTALAAYLLSTGRLTRWHGG
                     TLLALYGVYWVVSLVAFGEVPVELG"
     gene            complement(10001..11110)
                     /gene="pqqE"
                     /locus_tag="BLS21_RS05390"
                     /old_locus_tag="SAMN05660642_01089"
     CDS             complement(10001..11110)
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948562.1"
                     /locus_tag="BLS21_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01089"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_217635992.1"
                     /sec_met_domain="PTHR43273 (E-value: 2.4e-30, bitscore:
                     100.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.7e-23, bitscore: 76.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.1e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.7e-10, bitscore: 34.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.3e-09, bitscore:
                     30.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSAVERPFGLLAELTYRCPLHCSYCSNPLDLAAYADELTTAEWR
                     RVLTEARELGVLQLHLSGGEPLLRRDVAEIVQCAGELGLYTNLITSGLGLTPHRAEELL
                     AAGLDHVQISLQADEAALSDRIAGVRSFEHKLAAARLVKQLGWPLTLNVVLHRHNVDRL
                     AGILDLAEQLEADRIELAHTQYYGWALHNRGGLLPSRAQLERAQEVVRAAHARLQGRVD
                     VVYVLPDYFSRYPKPCMGGWGRRQLTVVPDGGVLPCPTAHTLPLPRASVREHSLAWIWE
                     RSPLFQRFRGTDWMPEPCRSCDRREVDFGGCRCQAFQLTGDAARTDPVCHLSPDHGLVA
                     EAVAAADEGARSGEVVLTPRRHPAAGRSR"
     gene            complement(11103..11411)
                     /gene="pqqD"
                     /locus_tag="BLS21_RS05395"
                     /old_locus_tag="SAMN05660642_01090"
     CDS             complement(11103..11411)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948561.1"
                     /locus_tag="BLS21_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01090"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_217635994.1"
                     /sec_met_domain="PqqD_RRE (E-value: 4.3e-22, bitscore:
                     72.7, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.8e-14, bitscore: 46.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTADGTDRPRLARHVRMGFDPARGQHVLLTPEAVTVLNRTGAAV
                     LELCDGQRTVTEIVAELRGRYASVDDDEVRVFLDRLAARRCLETGDAEAGRGRARRA"
     aSDomain        complement(11145..11405)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLS21_RS05395_PqqD_RRE.1"
                     /evalue="2.40E-23"
                     /identifier="RREFam006.1"
                     /label="BLS21_RS05395"
                     /locus_tag="BLS21_RS05395"
                     /protein_end="89"
                     /protein_start="2"
                     /score="72.7"
                     /tool="antismash"
                     /translation="TADGTDRPRLARHVRMGFDPARGQHVLLTPEAVTVLNRTGAAVLE
                     LCDGQRTVTEIVAELRGRYASVDDDEVRVFLDRLAARRCLET"
     gene            complement(11398..12102)
                     /gene="pqqC"
                     /locus_tag="BLS21_RS05400"
                     /old_locus_tag="SAMN05660642_01091"
     CDS             complement(11398..12102)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948560.1"
                     /locus_tag="BLS21_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01091"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_091214810.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.8e-100, bitscore:
                     329.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLIDTTGTATDEFVAALREHSRRYHDQHPFHRRMNAGELDAEQI
                     RCWVANRFCYQAAIPRKDAAIIANCPDREVRRRWLRRIVDHDGTADGDGGIEAWLRLGE
                     AVGLTRPELEDQRHVVPGVRFAVDAYVTFARTRPWVEAVASSLTELFAPDLMAERLAAF
                     ERHYTWIDPQELTYFRARLTQAPRDSAHALEVVTEHCRTPEQQAAALAALSFKCDVLWS
                     MLDAIDRACADR"
     misc_feature    complement(12100..12115)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.28"
                     /tool="antismash"
     gene            complement(12111..13004)
                     /gene="pqqB"
                     /locus_tag="BLS21_RS05405"
                     /old_locus_tag="SAMN05660642_01092"
     CDS             complement(12111..13004)
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948559.1"
                     /locus_tag="BLS21_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01092"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_091214813.1"
                     /transl_table=11
                     /translation="MWVRVLGSAAGGGFPQWNCACPPCRAVREGSRPARPRTQSSVAVS
                     ADRRRWSLLNASPDVRAQLESCTDLHPDGAGEVPLQAVLLTDAELDHTLGLLLLREGGG
                     LVVHATEATRDTLHDGTALLRTLEAYCPVEWRPVVPGADVPLGDGLSYRAFDVPTTKRA
                     RFGSGPREGRVVGYRLTDERSGRALVHLPVLQALTPEVCAQLEDCACLLVDGTCWSDDE
                     LIRLGRGGRTAREMGHLPISGPGGSLEQLAPLPVERRIYVHVNNTNPILLEDSPERRAV
                     EEHGLEVAVDGLDLEV"
     gene            complement(13086..13208)
                     /gene="pqqA"
                     /locus_tag="BLS21_RS05410"
                     /old_locus_tag="SAMN05660642_01093"
     CDS             complement(13086..13208)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: protein motif:HMM:TIGR02107.1"
                     /locus_tag="BLS21_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01093"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_139177020.1"
                     /transl_table=11
                     /translation="MDQELCVSPLRTEEWETPSFEEIRVSAEATAYMGVQEDWD"
     gene            complement(13214..14944)
                     /locus_tag="BLS21_RS05415"
                     /old_locus_tag="SAMN05660642_01094"
     CDS             complement(13214..14944)
                     /EC_number="1.1.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948557.1"
                     /locus_tag="BLS21_RS05415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01094"
                     /product="PQQ-dependent dehydrogenase, methanol/ethanol
                     family"
                     /protein_id="WP_091214819.1"
                     /transl_table=11
                     /translation="MTDIQDRTDIEYGEAPPPVDFGSLTTAPGTAPPVAQDVTYERILD
                     ARSEPQNWLTYYGAYDGQRYSPLDQITTENVVRLTPAWVFSFSPHGLHAGQSTYAFENC
                     PIVVEGVMYVSGWDGWVWALDAKTGQLLWQYKHAIPFDVSLCCGNVNRGVAVAHGKVFV
                     CTLNAHVLALDATTGECLWDVTSGDVRAGESLTVAPLVVKDRIVVGSSGGEFGVRGHLD
                     AYDMETGERVWRCYTIPKPGEPGSETWPQEGEAWARGGANGWITGTFDPETNLLYWGTG
                     NPAPDFDGEVRPGDNLYTDSVIAVDADTGEIRWHYQCTPHDLWDYDSNMECILFEQDGR
                     KLLAHFDKNGYCFVLDRTNGERVRIFPFVDRITWGEISPDGQVTPRIYPDKEGEEVHFY
                     PGPAGAKEWTHAAYSPRTELFYVPVQDTGATVARRRREFKEGIPYWGAAVTVDAKDMAG
                     SVSAFNASGEEVWRWRNDLPMCASVLVTAGDVVFAGTPSGTFVALDARSGEFLWQFNCG
                     SGHHSSPITYSVEGKQYVAVPVGWGAWVEGFLPGMMGGPHGQAMFVFSLPEDIDSAGGR
                     "
     gene            complement(14959..15423)
                     /locus_tag="BLS21_RS05420"
                     /old_locus_tag="SAMN05660642_01095"
     CDS             complement(14959..15423)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:1901661 - quinone metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948556.1"
                     /locus_tag="BLS21_RS05420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01095"
                     /product="MSMEG_3727 family PQQ-associated protein"
                     /protein_id="WP_091214822.1"
                     /transl_table=11
                     /translation="MTTTASERSSALRELGLDGQNQATIGRLLATGNIGHAEEGDDGRM
                     RARIRIVPDQLIWDPSVLVLPHGGHLDIEFVNDDQNTHCALVPSNGDSKWMWLPNYSRG
                     TMSVTLDGPGYYWFSSNIGNDEGRGLIGAIVVRGDVPESARLDRPKQPRP"
     gene            complement(15588..16748)
                     /locus_tag="BLS21_RS05425"
                     /old_locus_tag="SAMN05660642_01096"
     CDS             complement(15588..16748)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014740037.1"
                     /locus_tag="BLS21_RS05425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01096"
                     /product="glutathione-independent formaldehyde
                     dehydrogenase"
                     /protein_id="WP_091214825.1"
                     /sec_met_domain="ADH_N (E-value: 2.9e-28, bitscore: 92.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-13, bitscore:
                     45.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVVYRRPFEVAVEEVPDPRIEQPNDVIVRVTSTCICGTDLYLY
                     EGRAGVEPGTVVGHENLGVVEEVGAGVTALEQGDRVVMPFTVACGFCRNCRAGSSGSCL
                     TVTPAGRAGSPYGGSPYGGVTPAPCAGGQAEYLRVPYADVNCLPLPAGTDHESDYVLLS
                     DVFPTGYHGCRLAGLSPGGTVAVYGAGPVGLMAAYCALLCGASGVFVVDGRPERLAMAR
                     DIGAVAVDPSAGDPAQQIRDLTGGEGTDTGVDAVGFPVPTETGDGEEPAAVLDQLVRTV
                     RPTGGLGVPGPCVRRGPDGVVPDAGPGTLLVTIGTLVDKGLRLGTGRADARRYDRQLRD
                     LITEGRARPSFVVSHELPLDEAPNAYQMVDQRVDGFTKVVLRPDAA"
     gene            16871..18349
                     /locus_tag="BLS21_RS05430"
                     /old_locus_tag="SAMN05660642_01097"
     CDS             16871..18349
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016296.4"
                     /locus_tag="BLS21_RS05430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01097"
                     /product="DNA-binding protein"
                     /protein_id="WP_091214828.1"
                     /transl_table=11
                     /translation="MNGAKGLTNGALPATNGAVLSDDDLKRIATARERFAAGADTVHGV
                     RSEILVSWYRCREEYEVDPGLERAPAAAEGSAHSMGHDVVFAELGGWAACAAGEVDGLD
                     GLVTVADCEGRVLASWGSRRLLRLAADSNLAAWSIWAERTSGTNGMGTSLESQRPVLVR
                     GPEHWCRSFDPWTCAGVAVRDVVTHEPLAVLNVSCWRTPQPGAVLPWLSRVAAATEAKL
                     RQRARHTGTLLAAAFADARVPSATPLAAVDTAGKVVLANSAAAVLIGTPADTPAYAPAQ
                     RWTPQVPGVPELVRWVTERARQDPCWRGSTRVYVPFLGTPLPVAVRPVLTGTQVIGALL
                     ALGSADGSDVGGSDAGVPDTGAPDAATPPGRPGASLPCPRLPSRVVALREDRWVLLDPR
                     EIRFAETDHNNVWLTTDQGRLQAAARGLDRLEQDLVDKGFLRVHRRFLVNLGRVREIEP
                     GFKGTLFLATDTRVHETVPVSRRHAPSVRQALGL"
     gene            18371..19567
                     /locus_tag="BLS21_RS05435"
                     /old_locus_tag="SAMN05660642_01098"
     CDS             18371..19567
                     /EC_number="3.4.13.19"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070573 - metallodipeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948553.1"
                     /locus_tag="BLS21_RS05435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01098"
                     /product="dipeptidase"
                     /protein_id="WP_091214831.1"
                     /transl_table=11
                     /translation="MASAPPAALTTARDLLRHHPLVDGHNDLAWRIREGSGLDLRRVDL
                     AAPVVGTHTDLPRLRRGGVGAQFWSVYVPGALQGEAALATTLEQVDLVHRMIGRHPDDL
                     ELALSADDVEGAFARGRIASLLGAEGGHSIAGSLGVLRMLHRLGVRYLTLTHNVNVPWA
                     DSATDVPATGGLSAFGEEVVREMNRLGMLVDLSHVADSTARDALRVTEAPVVFSHSGAR
                     AVCDHPRNVPDDLLRGLAANGGVCMVTFVSDFVSPGCRAWALGLRAEVERRGLDPRDAA
                     VRAAVAGEHLADHPRPRATLAQVADHVEHVRRVAGVDHVGLGGDYDGAEDLPEGLEDVS
                     CYPALIAELLDRGWRRDECARLVGGNVLRVLREAEALARSASARRGPSTARIEDLDRA"
     gene            complement(19581..20762)
                     /locus_tag="BLS21_RS05440"
                     /old_locus_tag="SAMN05660642_01099"
     CDS             complement(19581..20762)
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079552.1"
                     /locus_tag="BLS21_RS05440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01099"
                     /product="cation:proton antiporter"
                     /protein_id="WP_091214834.1"
                     /transl_table=11
                     /translation="MDHVAQLLLELGLLFVGLSLIGLLARRLGLSSVPFVLLAALALGE
                     GGIAPLTTSEPFIEAAAEVGVVLLLLALGLEFTADELFASLRHHGPSGLVDLLLNAPPG
                     FVAGLLLGLPWQGALALAGVTWISSSGIVARLLGDLGRLANRETPAVLSVLVLEDLAMA
                     LFLPLLAVALAGGGPTTAVAGIALAGGAVGLALLAAQRQGHRLGRLLASDDDEQVLLRL
                     MGLTLLVAGLAQAAGASAAVGAFLVGLALPTAVADRARAVLGPLRDLFAAIFFVAFGLS
                     TDPGAVLPVLPAVLLLALVTAGTKVATGWFAARRDGVAVPGRLRAGTALVARGEFSVVI
                     AGLAVTAGVTELGPLATGYVLVLAVAGPVLTRLAEPRARPARPRPPAPGRAAA"
     gene            complement(20770..21255)
                     /locus_tag="BLS21_RS05445"
                     /old_locus_tag="SAMN05660642_01100"
     CDS             complement(20770..21255)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948864.1"
                     /locus_tag="BLS21_RS05445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_01100"
                     /product="cation:proton antiporter regulatory subunit"
                     /protein_id="WP_091214836.1"
                     /transl_table=11
                     /translation="MDLEETMLPGVGVRYRLRTRSGEVLAIVLDREGTAEVAVYDRRDP
                     DRARGVLRLEPDEVDAVAEVLGAPRLTQRFADLSREVPGLESGRFPIREGSRFAGRPLG
                     DTRARTLTGCSVVAIVRDADVVPSPGPGDLLHPGDVVVAIGSARGLADLERRLDEPA"
     misc_feature    21670..21684
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 ggacctccgc tgctcctcct ccacggctat cccgagacgc acctggcctg gggcctggtg
       61 gccggcgagc tcgcccggac gttcacggtc gtcgcgcccg acctgcgcgg gtacggggac
      121 agctccaagc cggccgcggt gcccggccac gagagctacg gcaagcgggc catggcggag
      181 gactgcatcg cactgatgcg tggactcggc ttcgacgcct tcgacgtcgt cggccacgac
      241 cggggcgggc gggtcgccta ccggatggcc ctggaccacc ccgaggtggt ccgccgactc
      301 acggtgctgg acgtcatccc gaccggcgag gtctgggccc gggccgacgc ccgcttcgcc
      361 ctcggctact ggcactgggc cttcctggcc cagccctccc cgatccccga gcggctcatc
      421 ggacgggatc ccgacttctt cctgttcgac gccgagttcg gtggcgccat ccgccggttc
      481 cccccggtgg cggtggccga ctacgcccgc tgcgccaggg acccggcgac cgtcgaggcc
      541 atgtgcgagg actaccgggc cggggccacc tgcgaccgcc gggaggacga cgaggaccgc
      601 gcggcggggc gacggatcac ctgccccacg caggtgctct gggcgggcag gggtgcgctc
      661 gaggcctggt acgacaccct cgcgatctgg cgggagtggg ccgacgacgt caccggcggg
      721 gcgatcgact gcgggcactt catggtcgag gagagtccgc acgagacgct gtccgcgatc
      781 cgggggttcc acgccggcca ccggagcccg gccgggtccg cctgacccgg cggccgcatc
      841 aggtcacctg accgatgcgg ccgcccggac gccggggcaa cgtccctgcc tgcggcacgc
      901 cgtccccgac gtccgggcgc ggcgggtgcc acctcagccg ccgaccagtt ccggagggga
      961 tcaccatgac cgaggccacc gcgaacggcg cccggccgac cgtcgcactc gtccacgggg
     1021 ccttcgccga cagcgcgggc tggaccgacg tcgtcgcccg gctcctcgcc gacagggtgc
     1081 gggtgcgggc cgtctccaac ccgctgcgcg gcatcgccca cgacgccgcc tacgtggcca
     1141 gcgccctctc gcagatcgac ggaccggtgc tcgccgtcgg tcactcctac ggcggtgcgg
     1201 tcatcacgaa cgccgcgctg cgggcgggca acgtcgtcgg actggtctac gtcgccggct
     1261 tcgcccccga cgagggggag accctgcagg acgtcgaggc cgactccagg gacagcgtgc
     1321 tgctcacggc cctgctccag tggagctacc cgacggccga cggcgggacg gagaccgagt
     1381 tcgcgatcga cccggaccgg ttccacgacg ccttcgccgc ggacgtgccg gaggagcagt
     1441 cccgcgtcat ggcggccacc cagcgacccg tctccgccct ggccttcggt gagccgacca
     1501 cggcgccggc gtggaaggac ctgccgtcct gggccgtcgt ccccaccggc gacaaggcgg
     1561 tcggcagcga cgtcctgcgg accatggcgg cacgagccgg cgccacggtg accgaggtgg
     1621 agggctccca cgtgatcatg atctcccggc cggaggtcgt caccgaggtc gtccggcagg
     1681 cgctccgggc cgtcccggcg tagcgctcgc cggccgctcg ggccgtcggg accgcgtccc
     1741 ggtcccgacg gcccggccgc gcccggctca gccggacgcg ccctccgcgg gggtcatccg
     1801 cagcagccgg accccggtca tctccagtcg caggcccgcc gcgtcggagg cgcagcggag
     1861 cacgacctgc atgcagcccg ggcaccggac gacgagcgca ggcgcgtcgg cgtagaccag
     1921 gtgctccccc aggggcgccg ggcgtccgca gtgcgcgcag gtcgagacgg ccgtcgtcgg
     1981 gtccaccgcg aagacctcac gcaggacccc gcccgccgcg ttgccgtcca gccgccgatc
     2041 acccgtctcc gggacaccgg tcacgggaca cacctccgat ccactccgac ctgcgcgtca
     2101 tcgatccgtc cagccggggg accaggcgtc gtcctcgtcg gggacgacgt gcaccgctcc
     2161 ctcctcggcg gaggccgccc ccgagtcgat gcccacgtcg agggcgtaca gctccggctc
     2221 gacgtccccc caacgctcgg cggtctccac cagccgcccc gcgcggcggc cgccgacctc
     2281 gtcgtcgatg agctccccgt cggtgtcgga ggcgtccccc agtccgtccc cctcgacctg
     2341 ctgctgctcc gggacctcac gggcgagtcg acccgccagg ctctccccgg ccagctcctc
     2401 gcgttcggtg gtcccccagt ccgtgaccgc ccacgggcgc tcggccgggg accaaccggt
     2461 gtcgagcacg tcggtgacgc cgccgaggtc ctccagggtg tcctgcggct ccaggacgcc
     2521 ggagtcctcc tcgggatcgg tcccgtcggt gccgaagacg aacgggtcca ccgcacacct
     2581 cctcgacccc gggccggagc aggggcgagc gctcaccagc gggccgctca cccgcctccc
     2641 gtcgggaacc gtggcaggac cgaccacgtc gacgcatcgg tcatccgact ggaggtcgcc
     2701 gctccccggg cccgaggtcc ctggtggccc gcccgagggt gagagacact ctcaccgaca
     2761 cacggacgac cggaccagcg acctccacga ccgagggctc gcctaccggc accgccgggt
     2821 gcgcgcggga ggggactccg ttgccagaag cgctcgcccc cgtccgcacc gcggacgcgg
     2881 gcctgatcgg ccggtcggcc gagtgtgcgg cactcgcctc cttcctcgac cgggcgctga
     2941 gcaccggcgc cgtcctcctg gtgaccgggg aacccggcgt cggcaagacc ctgctgctgg
     3001 agacggccgc gcgggacgcg gcggcctccg gtgccacggt cgtccacgct gccggcgtcg
     3061 agttcgaggc cgaggtgggc ttcgcgggcc tcaaccagct cctgctgccc ctcctcgacg
     3121 acctggagac gctccccgag ccgcaccgcg aggcgctggt cgtggccctc ggcctgggtg
     3181 cggggccgcc atcccaccgg ctgctcgtct cggccgccgt cctgggtctg ctcacgcggg
     3241 cggcggagtc ccgcccggtg ctggtcgtcg tcgacgacgt gccgtgggtg gaccggccga
     3301 gcgagcgggt cctcggcttc gtcgcccgcc ggctggaccg cagccggatc ggcctgatcg
     3361 ccgcggcgcg gaccggcagc gactgtgtcc tcctccaggc gggtctgccc cagctcgagg
     3421 tgcccccgct gggcgaggac gccgccacgg aactgctgcg ggcccgcttc cccgtgctcg
     3481 acgcgcagat ccgccggcgc gtcctcgagg cgtcccaggg caacccgctc gccctgctgg
     3541 agctccccgc ggtcatgacc gaggcccagc gcaccgggtc cgaccccctc ccgtcggcgc
     3601 ttccgctgag cagccacctg cagcgggtct tcgcccagca gctcgccgcc ctccccgagc
     3661 ggacccggga actgctgctc ctcgccgccc tcgaggggac gggggacctc cggacactgc
     3721 gtgcggcggc agccaccgac gggtggctcg acgacctggc cccggccgag cgagcacggc
     3781 tgctgcgcat cgacctcgcc gcgggacgcg tgaccctgcg gcacccgctc atcgggtcag
     3841 cggcggtcca gctgtcgacg agcggtgagc tgcggcgggc acacggcgcc ctggcccacg
     3901 tcctggtcga ccgaccggag gagtgcgcct ggcacctcgc cgaggccgtc gtgggcgccg
     3961 acgcccgcgc cgccgacctc ctcgagaccg cggcgcaccg cgcacggcac aagggcgacg
     4021 cggtgcacgc ggtcaacgcc ctcctccggg ccgcagacct caccccgagc ggtccggacc
     4081 gagcccgccg gctggcggcc gccgcgttcg tgggtgccga cacgaccggg gacctgcgca
     4141 acgtgcccca gctgctgtcc gcggcccgca cggccgaccc ccggacggca gggtccctcg
     4201 aggtcgcggt ggccgccgcg caccacctgc tcaacgggga gggtgacgtc gagacggcgc
     4261 accgcatgct cgtgcgggcc gtcgagtacg cgctcgacca cggatccggc gcggccacgg
     4321 tcgaggacgc actgcacagc ctcatgctgg tgtgccactt cggcggccgg gacgagcttt
     4381 ggcgcccctt cgagtgggcg ctcgaggccc tggggccgga cctcccgccg gtgctgtcgg
     4441 tgtcgcgcac ggtgttcgcc gaccccgtcc gcgcggcgcc ggcggcgctc gagcggctcg
     4501 acgagctgat cgtctccgcg cacaccggcg tcgatcccac ccacgtggtc cgcgtgggca
     4561 tggccgcctt gtacgccgat cgcctctccg gttgccggca ggcgctccgg agggtggtca
     4621 gggacgggag gcagggcggc gcggccgcct cggccgtcaa cgccctgatg ctgctgtgcc
     4681 acgacgcctt cgacggaggt cgctggcagg aggccggacg cacggccgag gagggccgcg
     4741 cgtggggtga ggagctgggc taccggctca tcaccctgtc cggcgtctac tgctcggccc
     4801 tcctggcggc cgcgcgaggg gatgacggga cggcggagac cctggccgac gagctcgtca
     4861 cgtggtcggc gccgagagcg gtccgtctgc tcgaggactt cgcccaccgc gtccgcgggc
     4921 tggccgcgct gggacgcggg aacttcgagg acgcctaccg ggagctgagc gccgtcagcc
     4981 agcccggtgg cttcgccccg tacgccccgg tcggcctcac cgtcgccatg gacctggtgg
     5041 aggccgcggt gcgcacgggc cgccgtcccg aggccgcggc gcacgtggcg gccatggagc
     5101 gggccccgat cttcaccggc cggccgaagc tcgctctcgt gaaggcgggc tccgcagctc
     5161 tcgtggcacc gggtgaggag gcgtcccggc gtttcgagga ggcgttggcc gtccccgggg
     5221 ccgagcagta ccccttcgaa cgcgcgcggg tccagctcgc ctacggggag cacctgcgcc
     5281 gcagccgcgc gacgaacgcc tcccgcgtgc agctcacggc ggcgctggag aggttccggc
     5341 agctcggggc gcgaccgtgg gcgacgcggg cggccaacga ggtccgggcg accgggctga
     5401 cccaccgcgg cgcgaccggt gaccggggcg ccggcgcact gaccgcccag gagcaccaga
     5461 tcgccatgct ggccgcctcg ggtctgtcca acaagcagat cggcagccgg ctgtacctct
     5521 cgccccggac ggtcggtgcc cacctctacc gggtcttccc gaagctgggc atcacctccc
     5581 gggccgcgct gcgggacgcc ctgagcggca ccgcacgcga ggcggccgcg gaggctgcgg
     5641 ccgtggtcct ttgactgatg ccccggtccg ccgtggcggg gagagtcggc accgctggag
     5701 gtgacgccgg ggaggagccg tcatgtcact ggtctctcga gggttcggac gccgggagca
     5761 gcgccgggac gagcgactgc ccccgggcca gtacgacgcc ggcgacctct tccccgtgct
     5821 gtccgccggc ccgacgccgc ggacgccgct gggcgagtgg gacctgacgc tgcagggcga
     5881 ggtggacggc ctgcggcgct ggacctggga cgagttccgg gagctgccgc gcgaggcggt
     5941 ctcggtcgac atccactgcg tcaccaagtg gtcgaagttc gacacccgct gggagggcgt
     6001 cgcggtcgac acgctgctgg ccggcgtccg gaccgaggcg gcgtacgccc tcgccttctg
     6061 cgacggcggg tacaccacca accaccgact gagcgacctg accgacggcc gggcgtgggt
     6121 ggtggacacc tacgacgggc agccgctcgc acccgagcac ggagggccgg tccggctgct
     6181 ggtcccccac ctctacttct ggaagagcgc caagtggctc cgcgggttcg cactcagcca
     6241 gttcaacgag ccggggttct gggagacgtt cggctaccac gatcgcgggg acccatggct
     6301 cgagcagcgg tacagcggcg actgaactgg ctgcgcgcca cggtcctcga gaaccgcccc
     6361 gagaccgctc gcgtccaccg gctcctcctc gacgtccccg gctggccggg ccacctgccc
     6421 ggccagcacg tcgacctgcg gctgaccgcc gaggacggct acacggccca gcgcagctac
     6481 tcggtggcct ccgcccccga ggacccccgg ctgcacctgc tggtcgagcg gttcgagggt
     6541 ggtgaggtgt cgccgtacct caccgacgaa ctgcgctccg gtgacctgct ggagctgcgc
     6601 ggccccatcg gcgggtactt cgtctggtcg tccgccgtgg accgggacgg ggggcgggcc
     6661 gagggccgcc gccccgtgca gctcgtcgcg ggtggcgccg gcgtcgcccc gttcctcgcc
     6721 atgctggacc accaccggcg cacgggcggg tccacaccgg tgcggctgct gtactcggca
     6781 cgcacggccg acgacgtcct cgcccccgac gtcctgggcc cgcagacgac gatcacgctg
     6841 acccgggagg cgccgtcgga ctggaggggc ctgaccggcc ggatcgaccg ccgcatgctg
     6901 gaggcgcaga ccttcgcgcc caccacccgg ccgcgggtct tcgtgtgcgg ccccacgtcc
     6961 ttcgtcgaga gcaccgccac gacgctcgtc gacctcggtc acgacccgtc gtggatcagg
     7021 ctcgagcgct tcggcgggtc cggcgatccg tcgtagagga gcggcgcatg tccgtcagga
     7081 gccgggtact ggccgttgcc gcggcgacga ccacggtcgt cggtacgggc acggtggcga
     7141 tgcccccggc gagcgcggcc accccggcct gcggcccggg ttgcatcgcg gtcttcagcc
     7201 ctgagttcgg cacgcacggc gacccccagt tcgtggaggc ggtgctcgac ggggtgggca
     7261 cggtcggcca gcccctcgtc ctgcagcgcg ccggcagctc tgacccgtcg caggacttcc
     7321 tgccccgcgg cggcctggtc tccgacttct tcgcgaccgg catggtctcc gccgcggtga
     7381 acggtcacta cggcagcctg cgcgcagcgc agctggagta cgcgccctcg ggtgtcgcca
     7441 gcggcctgtg cgtgggcctg gccggcaccg cgtacgagga cgagccgctc ggcctgcagc
     7501 cgtgcagcgt cccggggacg accgtgtgga tcgtcgacac cgcggactcg cccgcgaccg
     7561 cggccgacgg gtactccccc ctcgtcaacg gctcgacgac ggacgtcacc cacccgttgg
     7621 cgatgaccta cccggccgac gccgccccga ccgacgaacc ggctccgcag atccacgtga
     7681 gccgcctgca ctcctgcggc catgcggacc cggcggggcg cgcagtgccc gaccggcagc
     7741 tctggggaac ggtgctcggc gtcctggagt agcggtcggc gacggcgcgg ccccggggcc
     7801 ccgcgtcgtg ccgcgggtcc ggaggaacgg cggccggccg ggcgcggagt tgggaacggc
     7861 ggcgacgcgg gtacctccgt cccgttccgg cccgccggac cggagcaggg gctgacgagc
     7921 ctcggcccct ggccacgctc cgatcgggga gggatccctg tgacccagca gctgaccacc
     7981 ctgaccctgg acgacgcccg ccgcatcgtc gcggccggag aggcccgcgc cgcggagatc
     8041 gggcagccga tgaacatcgc ggtcgtcgat gcagggggtg acctcgtcat gcacgtccgg
     8101 atggacggcg cctggcgcgg cagcgtcgac atcgccatca acaaggcctt caccgcccgg
     8161 gcgttcgaca tcgccaccgc cgagctggcc gacctggcca agccgggcgg cccgttctac
     8221 ggcatccagg cgtccaacaa cggcaaggtg atggtcttcg ccggtggcgc gccggtgctc
     8281 gtcgacgggg tcgtcgtggg cgcggtcggg gtgagcggcg gcaccggcga gcaggacacg
     8341 acggtctgcg aggcggccac cgccggcctc tgacgtccgg cccctacgcc ggcagccggc
     8401 cggcccggcg cagcgcggcc agtccgtccg gcgtaccggg ccagtgccgg tcgagcgcag
     8461 ccgccccggc gtggcggacc accgagcgca gcacgagggc gaccacgatc gcgtcgtcgg
     8521 cgtggccgag caccggcacg aagtcgggca ccaggtcgaa cggcagcgcc aggtagccca
     8581 gcaacagcca cagccgcacc cggacgccgc gcggcagcgt gccgtcgccg gccagccggt
     8641 gcacgagcct gagcacgtcg ggcagcagcc gcagcagctc ccgcagccgc aggtcgtccg
     8701 ggcgggtcgc ccacagcacg gccatcagga ccagccagca cagcagcagg ccacccagca
     8761 ccccgaccag cgtccacgcc cagtccggca tcccgccgcc acctctccgc cgccccgcac
     8821 cccgagcatc gtcctggaga gggtccgcct tcacccgagt tcgaccggga cctcaccgaa
     8881 cgcgacgagg ctgaccaccc agtacacgcc gtagagcgcc agcagggtgc cgccgtgcca
     8941 ccgcgtcagc cggccggtgg agagcaggta cgcagccagg gcggtgagga cgacgagcgc
     9001 cggcaggtgc caggtgaaca cgtcccggcc gacgacgatg ccgccggcca ggagggtgat
     9061 gcccagcttc ccggtgacgg agaagacgac gctgccgatg acgttgccga ccccgatctc
     9121 cggcacgccc ctgcggaacg gctccaccgt caggaagacg tcctccatgg tgagcacggc
     9181 cgtggcgatc gtggcgccga acaccgtgcc ctcgagcccg taggccgcca ggatcccctc
     9241 ggtcccggtg ctcaccgtcg cggcgccgac gacgaggccg gcgagcgcga ccaccgccag
     9301 tccgaggtgg gcccagccgg gcaggtcgcg ctcgtcggtg cgcggcgcct cctcgacgac
     9361 ctgctgcgtc cgttcggcgc cggcccgtgc gcccgccccg accgccgggg ccggccgcac
     9421 gtccgtcccc gccgcgcgca gggacgggac gtcgtccccg gcctcggcga cggcggcctc
     9481 gtacacctcc acgtcgcgga agaccgccac gctcctgcgg agctcccggg cggcgacgta
     9541 ggtgacgaac aggacgaaca gcccgaggag cagcagtccg tcggtcaccg tgagcggtcc
     9601 ggcgagcgtg accgcgacca tcaccagcgg ggcggcggcg aacaggacga ggtagtcgcg
     9661 cgggatggcg acctggctcg gccggatgac cgcggccacc gcgaggacga ccccggtgaa
     9721 cgacagcgcc gtcccgaaca cgacgccgag cgcgacaccg ctgaggtcct cgaggttcag
     9781 cccgacgccg agcgcgatgt cgtcgaactc gacgccggtg aagacgaccg ccagcaggaa
     9841 cagcgggatc cgcagaccgc tcgccgcccc gacgaggtgg gtgatgagct tctcggcgct
     9901 gaccacgagc agcgtcgccc cggagatgaa gacgaacacc gaggtcatgt cgtggggccc
     9961 tcctcgcgac cggccgtggg tggggggtgt cggcgggcgg tcaccggctg cgcccggcag
    10021 cggggtgccg ccggggggtc agcacgacct cgccggaccg cgcgccctcg tcggcggcgg
    10081 ccaccgcctc ggccacgagc ccgtggtcgg gcgagaggtg gcagaccgga tcggtgcggg
    10141 cggcgtcgcc ggtgagctgg aaggcctggc agcggcagcc gccgaagtcc acctcgcggc
    10201 ggtcgcagct gcggcagggc tcgggcatcc agtccgtccc gcggaagcgc tggaacagcg
    10261 gtgaccgctc ccagatccac gccagggagt gctcccggac gctggcccgg ggcaggggca
    10321 gggtgtgcgc ggtggggcac ggcaggacgc caccgtcggg caccacggtg agctggcgcc
    10381 ggccccagcc gcccatgcag ggtttggggt accggctgaa gtagtcgggc aggacgtaga
    10441 cgacgtccac ccgtccctgc agacgcgcgt gcgcggcccg caccacctcc tgggcgcgct
    10501 ccagctgggc ccggctcggc agcagcccgc cgcggttgtg cagggcccag ccgtagtact
    10561 gcgtgtgggc cagctcgatc cggtcggcct ccagctgctc ggccaggtcg aggatgccgg
    10621 cgagccggtc gacgttgtgc cggtgcagga cgacgttgag cgtgaggggc cagcccagct
    10681 gcttcaccag ccgggcggcc gccagcttgt gctcgaacga ccgcaccccg gcgatgcggt
    10741 cggacagggc cgcctcgtcg gcctggaggc tgatctgcac gtggtccagg cccgcggcca
    10801 gcagctcctc ggcgcggtgg ggcgtcagcc cgagcccgct ggtgatcagg ttggtgtaca
    10861 ggcccagctc gccggcgcac tgcacgatct cggcgacgtc gcggcgcagc agcggctcac
    10921 cgccggagag gtgcagctgc agcacgccca gctcccgggc ctcggtcagc acccgtcgcc
    10981 actccgccgt ggtcagctcg tcggcgtagg cggcgaggtc gagcgggttg gagcagtagg
    11041 agcagtgcag cgggcagcgg taggtgagct cggccagcag cccgaacggc cgctccacgg
    11101 cgctaggcac ggcgggcccg tccgcggccg gcctccgcgt ccccggtctc gaggcaccgc
    11161 cgggcggcga ggcggtcgag gaacacgcgg acctcgtcgt cgtccacgga ggcgtaccgc
    11221 ccgcgcagct cggccacgat ctcggtcacc gtccgctgcc cgtcgcacag ctccaggacg
    11281 gccgcgcccg tgcggttcag gacggtgacc gcctccggcg tcagcagcac gtgctgcccg
    11341 cgtgccgggt cgaaccccat ccggacgtgc cgggccagcc gggggcggtc ggtgccgtca
    11401 gcggtctgca caggcgcggt cgatcgcatc gagcatgctc cagaggacgt cgcacttgaa
    11461 ggacagggcc gccagggcgg ccgcctgctg ctccggcgtc cggcagtgct ccgtcacgac
    11521 ctccagggcg tgcgcggagt cgcggggggc ctgcgtcagg cgggcgcgga agtaggtgag
    11581 ttcctgcggg tcgatccagg tgtagtggcg ctcgaaggcg gccaggcgct cggccatcag
    11641 gtccggcgcg aacagctcgg tcagcgagga ggccaccgcc tcgacccacg gccgggtgcg
    11701 ggcgaaggtg acgtaggcgt cgacggcgaa gcgcacaccc gggacgacgt gccgctggtc
    11761 ctccagctcg ggcctggtca gcccgaccgc ctcgccgagg cgcagccatg cctcgatgcc
    11821 cccgtcaccg tcggccgtgc cgtcgtggtc gacgatgcgc cgcagccagc ggcggcggac
    11881 ctcgcggtcc gggcagttgg cgatgatcgc ggcgtccttg cgggggatgg cggcctggta
    11941 gcagaagcgg ttggcgaccc agcagcggat ctgctcggcg tccagctccc cggcgttcat
    12001 cctgcggtgg aaggggtgct ggtcgtggta gcgccgcgag tgctcgcgca gcgcggccac
    12061 gaactcgtcg gtcgccgtgc cggtcgtgtc gatcagcgtc atgaggggcc tcacacctcc
    12121 aggtccagcc cgtccacggc gacctccagg ccgtgctcct cgaccgcgcg ccgctcgggc
    12181 gagtcctcga ggaggatcgg gttggtgttg ttgacgtgga cgtagatgcg gcgctcgacg
    12241 ggcagcgggg cgagctgctc gaggctgccc ccggggccgc tgatgggcag gtgccccatc
    12301 tcgcgggccg tccggccgcc gcgcccgagc cggatgagct cgtcgtcgga ccagcaggtg
    12361 ccgtcgacca gcaggcaggc gcagtcctcg agctgggcac acacctccgg ggtcagcgcc
    12421 tgcagcaccg gcaggtggac cagcgcccgg ccgctgcgct cgtcggtgag gcggtagccg
    12481 acgacccgcc cctcccgggg accggagccg aagcgcgcgc gcttggtcgt ggggacgtcg
    12541 aaggcccggt acgacagccc gtcgccgagc ggcacgtccg cgcccggcac gaccggccgc
    12601 cactcgaccg ggcagtaggc ctcgagcgtg cgcagcagcg ccgtcccgtc gtgcagcgtg
    12661 tcgcgggtcg cctcggtggc gtgcacgacg aggccacccc cctcgcggag cagcagcagt
    12721 cccagcgtgt ggtccagctc cgcgtccgtg agcagcacgg cctgcagcgg cacctccccc
    12781 gccccgtcgg ggtgcaggtc ggtgcaggac tcgagctggg cacggacgtc gggtgaggcg
    12841 ttgagcaggg accaccgccg gcggtccgcg ctcaccgcga ccgacgactg ggtgcgcgga
    12901 cgggccggcc gcgacccctc gcgcaccgcc cggcacgggg ggcaggcgca gttccactgc
    12961 gggaacccgc cgcccgccgc cgaacccagc acccgcaccc acatgtcgat cggtggtcct
    13021 cccggtagtg cggagacgga gaggcgccgg accgcaccgc ccgacgcctc tccgcccgga
    13081 tccgtctagt cccagtcctc ctggacgccc atgtaggcgg tcgcctcagc ggacacccgg
    13141 atctcctcga aggagggggt ctcccactcc tccgtgcgga gcggggagac gcagagctcc
    13201 tggtccatcg ccgtcacctc ccccctgccg agtcgatgtc ctcgggcagc gagaacacga
    13261 acatcgcctg gccgtgcggg ccgcccatca tcccgggcag gaagccctcg acccaggcgc
    13321 cccagcccac cgggacggcg acgtactgct tgccctcgac gctgtaggtg atcgggctgc
    13381 tgtggtggcc gctgccgcag ttgaactgcc acaggaactc gccgctgcgg gcgtcgaggg
    13441 ccacgaacgt cccggacggc gtgccggcga agacgacgtc gcccgccgtg accagcacgg
    13501 aggcgcacat cggcaggtcg ttgcgccagc gccacacctc ctcgccggag gcgttgaacg
    13561 ccgacaccga ccccgccatg tccttcgcgt ccacggtcac ggcggcgccc cagtagggga
    13621 tgccctcctt gaactcccgg cgccgccggg cgaccgtcgc gccggtgtcc tgcaccggga
    13681 cgtagaacag ctccgtcctc gggctgtacg ccgcgtgggt ccactccttc gccccggccg
    13741 gcccggggta gaagtgcacc tcctcgcctt ccttgtcggg gtagatccgt ggcgtcacct
    13801 gtccgtcggg gctgatctcg ccccaggtga tccggtcgac gaaggggaag atccgcaccc
    13861 gctcgccgtt cgtgcggtcc aggacgaagc agtacccgtt cttgtcgaag tgggccagga
    13921 gcttgcgccc gtcctgctcg aacaggatgc actccatgtt gctgtcgtag tcccacaggt
    13981 cgtgcggggt gcactggtag tgccagcgga tctcccccgt gtcggcgtcc accgcgatga
    14041 cgctgtcggt gtagaggttg tcgcccggcc ggacctcgcc gtcgaagtcg ggcgcggggt
    14101 tgccggtgcc ccagtacagg aggttggtct ccgggtcgaa ggtgccggtg atccagccgt
    14161 tggcgccgcc ccgcgcccag gcctccccct cctgcggcca ggtctccgag cccggctcgc
    14221 cgggcttcgg gatcgtgtag caccgccaga cccgctcccc ggtctccatg tcgtaggcgt
    14281 cgaggtggcc gcgcaccccg aactcgccgc cggagctgcc gacgacgatc cggtccttca
    14341 cgaccagcgg ggcgaccgtg aggctctccc cggcgcgcac gtccccgctg gtgacgtccc
    14401 agaggcactc gccggtggtg gcgtcgagcg cgaggacgtg ggcgttgagg gtgcagacga
    14461 agaccttgcc gtgggccacg gcgaccccgc ggttgacgtt gccgcagcac agcgagacgt
    14521 cgaacgggat cgcgtgcttg tactgccaca gcagctgccc ggtcttggcg tcgagcgccc
    14581 agacccaccc gtcccacccg gagacgtaca tgacgccctc gacgacgatc gggcagttct
    14641 cgaaggcgta ggtcgactgg ccggcgtgca gcccgtgggg cgagaagctg aacacccagg
    14701 ccggggtcag gcggacgacg ttctcggtgg tgatctggtc gagcgggctg taccgctgcc
    14761 cgtcgtaggc gccgtagtag gtgagccagt tctgcggctc cgagcgggcg tcgaggatgc
    14821 gttcgtacgt gacgtcctgg gccaccggcg gcgcggtccc gggcgctgtg gtcagcgacc
    14881 cgaagtcgac cggcggcggg gcctctccgt actcgatgtc ggtcctgtcc tggatgtcgg
    14941 tcattgaccc agtcctgtct acggtcgggg ctgcttcggg cggtcgagcc gagcggactc
    15001 cgggacgtcg cccctgacga cgatcgcccc gatcaggccc cggccctcgt cgttgccgat
    15061 gttggagctg aaccagtagt aaccagggcc gtcgagggtg acggacatgg tcccgcgcga
    15121 gtagttcggc aaccacatcc acttgctgtc gccgttgctc ggcacgagcg cgcagtgcgt
    15181 gttctggtcg tcgttgacga actcgatgtc caggtgcccc ccgtggggca ggacgaggac
    15241 cgaggggtcc cagatcagct ggtcgggcac gatgcggatc cgcgcgcgca tccggccgtc
    15301 gtcgccctcc tcggcgtgcc cgatgttccc ggtggccagc agccggccga tcgtcgcctg
    15361 gttctgcccg tccaggccga gctcgcgcag cgccgaggat cgctccgatg cggtggtcgt
    15421 catcgacctt ccctcctggt tgtgtcgaag cggactgatg gggtgcctgc cgtgccgggg
    15481 tcggtcacgg ccaggccccc ggacgacggc ccgccgtccc gcgctcggcc ggcacctggg
    15541 tggccatggc acctcctccc cctccggttc ctgcagccgc gcgacgatca ggcggcatcg
    15601 ggcctgagca cgaccttggt gaagccgtcg acgcgctggt cgaccatctg gtacgcgttc
    15661 ggcgcctcgt cgagcggcag ctcgtgggac accacgaagc tcggtctggc ccggccctcg
    15721 gtgatcaggt cgcgcagctg ccggtcgtag cgcctggcgt ccgcccgccc ggtgcccagc
    15781 cgcaggccct tgtcgaccag cgtgccgatc gtgacgagca gcgtgccggg cccggcgtcc
    15841 gggacgaccc cgtccggtcc acggcgcacg cacgggccgg ggacgcccag cccgccggtg
    15901 ggccgcaccg tgcgcacgag ctggtccagg accgccgcgg gctcctcgcc gtcgccggtc
    15961 tcggtgggga ccgggaagcc gacggcgtcc acccccgtgt cggtgccctc accaccggtg
    16021 aggtccctga tctgctgcgc cgggtcgccg gcggagggat ccacggcgac ggccccgatg
    16081 tcccgtgcca tggcgagtcg ctcgggacgg ccgtcgacca cgaagacgcc cgacgcgccg
    16141 cagagcagcg cgcagtacgc cgccatcagt cccaccggcc cggcgccgta gaccgcgacg
    16201 gtccctcccg gcgagagccc cgcgaggcgg cagccgtggt acccggtggg gaagacgtcg
    16261 gagagcagga cgtagtcgga ctcgtggtcg gtgccggcgg gcagcggcag gcagttgacg
    16321 tccgcgtacg ggacccgcag gtactccgcc tgcccgccgg cacacggggc cggggtgacg
    16381 ccgccgtagg ggctgccgcc gtaggggctc cccgcacgac cggccggggt gaccgtgagg
    16441 caggagccgc tcgagcccgc ccggcagttc ctgcagaagc cgcaggccac ggtgaacggc
    16501 atcacgacgc ggtcgccctg ctccagggcg gtgacgccgg cgccgacctc ctcgacgacg
    16561 cccaggttct cgtggccgac caccgtgccc ggctcgacgc ccgcccgccc ctcgtacagg
    16621 tacaggtccg ttccgcagat gcacgtcgac gtgacccgca cgatcacgtc gttcggctgc
    16681 tcgatccgag ggtcggggac ctcctccacc gccacctcga agggcctccg gtagaccacc
    16741 gcccgcatgg ccgcccgccc ccctccggct gccgggtgcg ccctggaacc gcgcccggcc
    16801 cgctagcctg ctgctcctcg accgcggccc gagcctggga cgcgtccccc cacagcccaa
    16861 ggggaacggg atgaacggcg cgaaaggcct gacgaacggc gcgctcccgg ccacgaacgg
    16921 agccgtgctc tccgacgacg acctcaaacg gatcgccacc gcccgggagc gcttcgccgc
    16981 cggagcggac accgtccacg gcgtccgctc cgagatcctc gtgtcctggt accggtgccg
    17041 cgaggagtac gaggtcgacc cgggcctgga acgcgcccct gccgcggcgg agggcagcgc
    17101 gcactcgatg gggcacgacg tggtgttcgc cgagctcggg gggtgggcgg cctgcgccgc
    17161 cggggaggtg gacggcctcg acggcctggt caccgtggcc gactgcgagg gccgcgtcct
    17221 ggcctcctgg ggcagtcggc ggctgctccg cctcgccgcg gacagcaacc tcgccgcctg
    17281 gtcgatctgg gcggaacgga ccagcggcac caacggcatg gggacctcgt tggagagcca
    17341 gcgcccggtc ctggtccggg gccccgagca ctggtgccgc agcttcgacc cctggacgtg
    17401 tgccggcgtc gcggtgcggg acgtggtcac gcacgagccg ctcgccgtgc tcaacgtctc
    17461 ctgctggcgc acgccgcaac ccggtgccgt gctgccgtgg ctgagccggg tcgccgcggc
    17521 caccgaggcc aagctgcgcc agcgggcgcg gcacaccggc accctcctgg ccgccgcctt
    17581 cgccgacgcc cgggtgccgt ccgcgacgcc gctggccgcc gtggacacgg ccgggaaggt
    17641 cgtgctggcc aacagcgcgg ccgccgtcct gatcggcaca cccgccgaca ccccggccta
    17701 cgccccggcg cagcggtgga ccccgcaggt gcccggggtg cccgagctgg tgcgctgggt
    17761 caccgaacgc gcccggcagg acccctgctg gcgcgggtcg acgcgggtct acgtgccctt
    17821 cctcgggacc cccctgccgg tcgccgtccg cccggtcctc accgggaccc aggtgatcgg
    17881 cgcgctgctg gccctcggct ccgccgacgg gtccgacgtg ggcgggtcgg acgccggcgt
    17941 gccggacacc ggggcgccgg acgcggcgac gcccccgggg cgtcccggcg cctccctccc
    18001 ctgcccccgc ctgcccagcc gggtcgtcgc cctgcgcgag gaccggtggg tcctgctcga
    18061 cccgcgcgag atccgcttcg ccgagaccga ccacaacaac gtctggctca ccaccgacca
    18121 gggacggctg caggccgccg cccggggtct ggaccgcctc gaacaggacc tcgtggacaa
    18181 ggggttcctc cgggtccacc gccgcttcct cgtcaacctg ggccgggtgc gggagatcga
    18241 gccgggcttc aaggggacgc tgttcctcgc cacggacacc cgcgtccacg agaccgtccc
    18301 ggtctcccgc cggcacgcgc cctccgtccg ccaggccctc gggctgtagg cacgtcctcg
    18361 gaggaccggg atggcgagtg caccccccgc cgcactgacg acggcacgcg acctcctgcg
    18421 ccaccacccg ctggtcgacg gccacaacga cctggcgtgg cggatccgcg aggggtccgg
    18481 tctcgacctg cgccgggtgg acctcgcggc cccggtggtg ggcacgcaca ccgacctgcc
    18541 gaggctgcgg cggggtgggg tcggcgccca gttctggtcg gtctacgtgc ccggtgcgct
    18601 gcagggcgag gcggcgctcg ccacgaccct cgaacaggtc gacctcgtgc accgcatgat
    18661 cggcaggcac ccggacgacc tggagctggc gctgagcgcc gacgacgtcg agggcgcgtt
    18721 cgcccgcggg cggatcgcct cgctgctggg cgccgagggc ggccactcca tcgccggttc
    18781 gctgggcgtc ctccggatgc tgcaccggct cggcgtccgc tacctgacgc tgacgcacaa
    18841 cgtgaacgtc ccctgggccg actcggcgac cgacgtcccc gccaccggcg ggctcagcgc
    18901 gttcggcgag gaggtggtcc gggagatgaa ccggctcggc atgctggtcg acctgtccca
    18961 cgtggcggac agcaccgcac gcgacgcgct ccgggtcacg gaggcgccgg tcgtcttctc
    19021 ccactcgggc gcccgcgcgg tgtgcgacca cccgcgcaac gtccccgacg acctcctccg
    19081 cggactggcc gccaacggtg gggtgtgcat ggtgacgttc gtgtcggact tcgtgtcgcc
    19141 ggggtgccgc gcgtgggcgc tcgggctccg ggccgaggtg gagcgccgcg ggctcgaccc
    19201 gagggacgcc gccgtgcggg ccgcggtggc gggcgagcac ctcgccgacc acccccgtcc
    19261 gcgggcgacg ctggcccagg tcgccgacca cgtcgagcac gtgcggcggg tggccggcgt
    19321 cgaccacgtc ggcctcggcg gggactacga cggcgcggag gacctgccgg aggggctgga
    19381 ggacgtctcc tgctaccccg cgctgatcgc cgagctgctc gatcgggggt ggcgccggga
    19441 cgagtgcgcc cggctggtcg gcggcaacgt cctgcgggtc ctccgcgagg ccgaggcgct
    19501 ggcgcggtcg gcgtccgccc gccgaggtcc gtccacggcg cgcatcgagg acctcgaccg
    19561 cgcctgaccg accggcgggg tcaggccgcc gcccgcccgg gggccggcgg gcgcgggcgg
    19621 gcgggccgag cacgcggctc ggcgaggcgg gtgagcacgg gaccggccac ggcgaggacc
    19681 agcacgtagc cggtggccag cggcccgagc tcggtcaccc ccgccgtcac cgccaggccg
    19741 gcgatgacga cggagaactc gccccgggcc accagggccg tcccggcgcg cagccggccg
    19801 ggcacggcca ccccgtcccg ccgggcggcg aaccagccgg tggcgacctt cgtccctgct
    19861 gtcacgaggg ccagcagcag gacggcgggc agcacgggca gcaccgcgcc cgggtcggtg
    19921 gacagcccga aggcgacgaa gaagatcgcc gcgaacaggt cgcgcagcgg ccccaggacc
    19981 gcccgcgccc ggtcggcgac cgcggtgggc agcgccagcc cgaccaggaa ggcccccacc
    20041 gcggccgacg cccccgccgc ctgggccagc ccggccacca gcagggtcag acccatcagg
    20101 cgcagcagca cctgctcgtc gtcgtccgag gccaggagcc ggcccagccg gtggccctgc
    20161 cgctgggcgg ccagcagcgc cagcccgacg gcgccccctg ccagcgcgat gcccgccacg
    20221 gccgtcgtcg gcccaccacc ggcgagcgcg acggcgagca gcgggaggaa cagcgccatc
    20281 gccaggtcct ccagcaccag cacggacagc accgcggggg tctcccggtt ggccagcctc
    20341 ccgaggtcgc cgagcaaccg ggcgacgatc cccgacgagg agatccaggt gaccccggcc
    20401 agcgcgagcg caccctgcca cggcaggccg agcagcagcc ccgccacgaa gcccggcggg
    20461 gcgttgagca gcaggtccac cagtccggac ggaccgtggt gccgcagcga ggcgaacagc
    20521 tcgtcggcgg tgaactccag accgagggcg agcagcagca ggaccacgcc gacctccgcg
    20581 gccgcctcga tgaacggctc cgaggtcgtc agcggggcga tgccgccctc ccccagcgcg
    20641 agcgcggcca gcaggacgaa cggcacggac gacaggccca gccggcgggc cagcagcccg
    20701 atgagggaca gcccgacgaa cagcaggccc agttcgagca gcagctgggc gacgtggtcc
    20761 atcgacgccc tacgcgggct cgtccaggcg ccgttccagg tccgccagcc cgcgcgccga
    20821 cccgatggcc acgacgacgt cccccgggtg cagcaggtcg cccggccccg gggaggggac
    20881 gacgtcggcg tcccgcacga tcgccacgac ggagcagccg gtcagcgtgc gggcccgcgt
    20941 gtcccccagc ggccggccgg cgaagcgcga gccctcgcgg atcgggaacc gtcccgactc
    21001 cagccccggg acctcgcggg acaggtccgc gaagcgctgc gtcagccggg gagccccgag
    21061 cacctcggcc acggcgtcga cctcgtccgg ttccagccgc agcacgcccc gcgcccggtc
    21121 ggggtcgcga cggtcgtaga cggcgacctc ggccgtgccc tcccggtcga ggacgatggc
    21181 gaggacctcg ccggagcggg tccgcagccg gtaacggacg ccgacgcccg gcagcatggt
    21241 ctcctcgagg tccacagccg catggtggca gaccagcggc tgcgtaccgg gcggccggtg
    21301 ctcaggtgtg caggaccgcc gccccgccga accgtccgtg ggccaggtcc gacagcgccc
    21361 gcggggcgtc gtccatgggg taggcgacgg tggtggcgcg gacgccgagg cggccggcca
    21421 gccggaggaa ctcctcgccg tcgcggcggg tgttggccgt gacgctgcgc agccggcgct
    21481 cgccgaacag ctcggcggcg tagtccagcg cggggatgcg ggagagccag atgccggcga
    21541 cggccagtgt ggcgccgcgg tccagcgcgc gcagggccac ggggaccagc tcgccggccg
    21601 gggcgaacag gatcgcgccg tccagcggct cgggtggggg gtcggtcgcc gtccccaccg
    21661 agtccacgcc gagctgctcg gccagccgcc ggttgtgctc gccgcgggtg aggacgtgca
    21721 cccgcagccc ctgcgcgagc gcgacctggg cggtgaggtg ggcgctgccg ccgaagccgt
    21781 agacgccgag ccggcccccg ggtggcacgt cggcgcaccg cagcgcccgg tagccgatga
    21841 tcccggcgca caggagcggc gcggcccgct cgtcgcccag cccgtccggc agcgggtagg
    21901 cgaaggactc gtcgacgagg caggcgtcgg cgtagccgcc gtcgacgtcc cagccggtga
    21961 agaccggcgc ggtgcagagg ttctcctcgc cgcgccggca gaaccggcag ctgccgtcgg
    22021 tgctgcccag ccagggcacc ccgacccgct gccccacggt gaaccgggtg gcgcccgggc
    22081 cgcgggccga gacgcgcccg ac
//
