LOCUS       NZ_FNHE01000001        23340 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Geodermatophilus siccatus strain DSM 45419, whole genome shotgun
            sequence.
ACCESSION   NZ_FNHE01000001
VERSION     NZ_FNHE01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Geodermatophilus siccatus
  ORGANISM  Geodermatophilus siccatus
            Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
            Geodermatophilaceae; Geodermatophilus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900103785.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 01:00:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,951
            CDSs (total)                      :: 4,891
            Genes (coding)                    :: 4,846
            CDSs (with protein)               :: 4,846
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 11 of 45
            Pseudo Genes (incomplete)         :: 37 of 45
            Pseudo Genes (internal stop)      :: 5 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:54:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 125795
            Orig. end                         :: 149135
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNHE01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23340
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..23340
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23340
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13340]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13340
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(6..21)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(129..143)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.44"
                     /tool="antismash"
     misc_feature    165..180
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    207..220
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            complement(416..1573)
                     /gene="galK"
                     /locus_tag="BLS21_RS00585"
                     /old_locus_tag="SAMN05660642_00118"
     CDS             complement(416..1573)
                     /EC_number="2.7.1.6"
                     /GO_function="GO:0004335 - galactokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="galK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950046.1"
                     /locus_tag="BLS21_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00118"
                     /product="galactokinase"
                     /protein_id="WP_091212511.1"
                     /transl_table=11
                     /translation="MTAADVARKAFAEAFGGPPEGVWAAPGRVNVIGEHTDYNDGFVLP
                     VALPQTTRAAVARRDDGLVALVSAQHPDDRVEVPVTELAPGRPGGWAGYPAGVVDALRD
                     RVPGGVSVLVDGDVPAGMGLSSSAALSCSVALALRDLAAPDLAVADLVDVARRAENDFV
                     GAPTGILDQSASLLCTAGHALFLDTRDRSTEQVPLDLRAAGLELLVVDTGTTHDHATGG
                     YGDRRRECEQAAERLGVRALRDVPDVAALAPLDDGTSEGEVLLRRARHIVTENARVLEV
                     VRILRETADPGAIGPVLTAGHASLRDDFQISTVELDTAVDTALEAGAAGARMVGGGFGG
                     SAVVLVDADRTGGVARAITDRFAQQGFTAPRAFAVVPSAGARRLA"
     gene            complement(1570..2667)
                     /gene="galT"
                     /locus_tag="BLS21_RS00590"
                     /old_locus_tag="SAMN05660642_00119"
     CDS             complement(1570..2667)
                     /EC_number="2.7.7.12"
                     /GO_function="GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="galT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014742561.1"
                     /locus_tag="BLS21_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00119"
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="WP_091212514.1"
                     /transl_table=11
                     /translation="MIRTSRRLADGREILYFDAGDTAPPRTAEDPRDLPPVSTRSQLRR
                     DPLLGEWVVLASHRQTRTFLPPADLCPLCPTRPGREPTEVPEADYQVVVFENRFPSLAT
                     AVERDVPPTAPGAPLTELRPGFGRCEVVVFTSEHDRSFATLGADRARLVVDVWAERTAE
                     LSAVDGIGQVFVFENSGEEIGVTLSHPHGQIYAYPFVTPRVEKVLASVERHRRETGGDL
                     FADVLTAERAGPRVVTANEHWTAFVPAAARWPYELQVFPHRRVPDLPALTAAERDALAE
                     IYLDVLGRFAHRFDTPMPYIASWNQAPVGRGREDWWLHLQLFSLRRAPGKLKYLAGSES
                     GMGAFITDTVPEDVAEQLRNVGTAQ"
     misc_feature    2694..2707
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     tRNA            complement(2810..2882)
                     /anticodon=(pos:complement(128641..128643),aa:Glu,seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BLS21_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05660642_00120"
                     /product="tRNA-Glu"
     gene            complement(2810..2882)
                     /locus_tag="BLS21_RS00595"
                     /old_locus_tag="SAMN05660642_00120"
     tRNA            complement(2990..3062)
                     /anticodon=(pos:complement(128821..128823),aa:Glu,seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BLS21_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05660642_00121"
                     /product="tRNA-Glu"
     gene            complement(2990..3062)
                     /locus_tag="BLS21_RS00600"
                     /old_locus_tag="SAMN05660642_00121"
     misc_feature    3103..3119
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     tRNA            complement(3111..3182)
                     /anticodon=(pos:complement(128942..128944),aa:Gln,seq:ctg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BLS21_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAMN05660642_00122"
                     /product="tRNA-Gln"
     gene            complement(3111..3182)
                     /locus_tag="BLS21_RS00605"
                     /old_locus_tag="SAMN05660642_00122"
     misc_feature    3150..3170
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            complement(3168..4463)
                     /locus_tag="BLS21_RS00610"
     CDS             complement(3168..4463)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /locus_tag="BLS21_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_139176982.1"
                     /sec_met_domain="Abi (E-value: 3.7e-16, bitscore: 54.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAGPPGWAVPDDEPYAGPPPTGPYAAPPHVPGALYGGHAPPAA
                     GTAAGPVPWPLGPVPLQPGPHTAPPWGPPPAPPWVPPPGMRWQLPPGTPPHDEPVDYLQ
                     AMRSRDWHWWRPLLGLLLFTAVYLVATLVATAVVFVAGFATGALPDPTAIDPTDLTDPG
                     LLLLTNISLIVAIPCVWLSWAAAHGMRIGWSSSVLARLRWRLLAPYTLLALPTLAAGLL
                     LSVLLGFVAGDWEATGPVDGFGWLLLVVLLTTPLQSAAEEYVFRGYLSQAIAGWVGRPR
                     AGAVVAAVLTAALFSAAHLPPDVWTFLDRFAFGLAASAVVWLTGGLEAAIVLHAVNNVV
                     VFLLAGSLGEGVATDAVPAGTGVLVVLIDLLAMAAYVGLVVRTRRWLRPEVRTAALDLR
                     PPSPWGVPGPPPGIGYGVVQRREVQHHPWGMG"
     gene            complement(4468..5973)
                     /gene="gltX"
                     /locus_tag="BLS21_RS00615"
                     /old_locus_tag="SAMN05660642_00123"
     CDS             complement(4468..5973)
                     /EC_number="6.1.1.17"
                     /GO_component="GO:0009332 - glutamate-tRNA ligase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950049.1"
                     /locus_tag="BLS21_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00123"
                     /product="glutamate--tRNA ligase"
                     /protein_id="WP_091212519.1"
                     /transl_table=11
                     /translation="MTATGLPPTAPTTTRTRFCPSPTGMVHVGLLRTALFNWAHARHTG
                     GTFVFRIEDTDASRDSEESYRHLLDSLRWLGLEWDEGPEVGGPHGPYRQSERHEVYREV
                     AQKLLAAGHAYESFSTNEEVEARRLAAGQDPKLGYDNADRFLTDEQKAALRAEGREPVL
                     RLRMPDEDLAWTDLVRGEIRFAAGSVPDFVIVRANGVPLYPFVNPVDDALMGITDVLRG
                     EDLLPSTPRQLALYGALADIGVASGAPRFGHLPYVTGEGNRKLSKRDPQSNVDVYRERG
                     FVPEGFANYLALLGWSIAEDRDVFSMQEMVEAFDVTRVSANPARFDLKKAEAINATHLR
                     ALPVEDFTERVVPFLARAGLVAEPPTAEQWRVLETIAPLAQERMIVLSDAVGLLGFLFV
                     DDVEIDPAAAAKQLAGPEAAEVLDAAQAALRQLPEWTTPAIETALREALVEGLGRKPRQ
                     AFGPVRVAVSGRTVSPPLYESIELLGRERSLARLAAARAAVPG"
     gene            complement(5970..6782)
                     /locus_tag="BLS21_RS00620"
                     /old_locus_tag="SAMN05660642_00124"
     CDS             complement(5970..6782)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950050.1"
                     /locus_tag="BLS21_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00124"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_091212521.1"
                     /transl_table=11
                     /translation="MRIVRFASPSGMSFGVLDGDGQVAQIEGHPFGTISFTGQRYAQAD
                     VRLLSPILPSKVVAVGKNYAAHVEEMGTGDAPSQPLLFLKPSTTVIGPGDAIRIPPGST
                     NVHHEVELAVVIGARGARHVTPEQALGSVFGYTIANDVTERDMQASDGQWTRAKGFDSF
                     CPLGPWIETDLAGLGKDPADLEVTCTVDGELRQSGRTSQLLFGIPTLVSYISQVMTLLP
                     GDVVLTGTPSGVGPIRPGQRVECAIEGLGSLVNGVSGADTASTAGGLR"
     gene            6843..7244
                     /locus_tag="BLS21_RS00625"
                     /old_locus_tag="SAMN05660642_00125"
     CDS             6843..7244
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950051.1"
                     /locus_tag="BLS21_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00125"
                     /product="VOC family protein"
                     /protein_id="WP_091212524.1"
                     /transl_table=11
                     /translation="MACRFSELVVDSRDPEALAAFWAEVLGYEVLGREEDGAVEIGPVT
                     GFGGPAPTLVFAPVAEPTPGKVRLHVDVSPTDRDQDAELARLLALGATRADVGQREGRA
                     GEQDAVSWYVLADPEGNEFCLLRRRLDPL"
     gene            7270..7599
                     /locus_tag="BLS21_RS00630"
                     /old_locus_tag="SAMN05660642_00126"
     CDS             7270..7599
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014740176.1"
                     /locus_tag="BLS21_RS00630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00126"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_091212526.1"
                     /transl_table=11
                     /translation="MILIVIKMPVRPDRIDEFRTHADEYARAVNAEEGSLFFEWSRSVE
                     DPNTFVCIEGFRDSEAGASHVATPHAKAAFDWMSDLVAEQPQIIYIDAPEVSGFGPMGE
                     VQPRG"
     misc_feature    complement(7276..7289)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    7654..7669
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            7669..8787
                     /locus_tag="BLS21_RS00635"
                     /old_locus_tag="SAMN05660642_00127"
     CDS             7669..8787
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950053.1"
                     /locus_tag="BLS21_RS00635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00127"
                     /product="sensor histidine kinase"
                     /protein_id="WP_091212529.1"
                     /transl_table=11
                     /translation="MTRALAVLTCLALLTVVVEATDDPRPLLAVALGVTFAAHALVALP
                     WLAGQPVPRRYWLTAGHVCLQLPLGALMFGAAHAGVGATLLLLVLVAQSVLLLPLPAAA
                     VVTALVPLVHAGMGWADFARNGLGMLGAAVFTAVVTALLQREQQARGELAEANERLRGY
                     AAQAEELATTRERNRLARDIHDGLGHHLTVVQMQVQAARAVLPSDPGRADEVLAKAQQQ
                     ASEALAEVRRSVATLREPRTSPPLRAALEALTAEVSAAGVPATLEVVGTERRLPAEAEE
                     SLFRSAQEGLTNVRKHAAATSARVTLTYGDDGTVRLSVRDDGCGLPAGAHDADPRGFGL
                     VGLRERAARAGGQLVVAPVPGGGTELLVEVPG"
     gene            8784..9437
                     /locus_tag="BLS21_RS00640"
                     /old_locus_tag="SAMN05660642_00128"
     CDS             8784..9437
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950054.1"
                     /locus_tag="BLS21_RS00640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00128"
                     /product="response regulator transcription factor"
                     /protein_id="WP_091212531.1"
                     /transl_table=11
                     /translation="MSAVRVLVVDDQALFREALATLLGARPEVEVVGEAGNGHQALERA
                     AALQPDVVLMDLHMPVLDGIAATRRLKVEQPGVRVLALTTFDDDEDVFAALRAGALGYL
                     LKDVSSDRLVEAVLSAARGESVLQPSVAAKVVARFAQLDDAPRSRPQPLVVPLSDRELD
                     VLRLLADGRSNREIATALFLAEGTVKNHVTNVLGKLGARDRTQAALRARALDLL"
     gene            9517..9927
                     /locus_tag="BLS21_RS00645"
                     /old_locus_tag="SAMN05660642_00129"
     CDS             9517..9927
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950055.1"
                     /locus_tag="BLS21_RS00645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00129"
                     /product="hypothetical protein"
                     /protein_id="WP_091213670.1"
                     /transl_table=11
                     /translation="MTTQTPPRHAHSRGRRTWHLVRHYLEMVVAMVVGMAVLGPVEALL
                     WPGVDDRVDVHAVVMATNMAVAMAAWMRFRGHSWPAIAEMSAAMYVPFAVLLVPYWAGA
                     VSGSFLFTAGHVLMLPAMALAMWWRLDEYAGC"
     gene            complement(10001..11575)
                     /gene="cimA"
                     /locus_tag="BLS21_RS00650"
                     /old_locus_tag="SAMN05660642_00130"
     CDS             complement(10001..11575)
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950056.1"
                     /locus_tag="BLS21_RS00650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00130"
                     /product="citramalate synthase"
                     /protein_id="WP_091212533.1"
                     /sec_met_domain="HMGL-like (E-value: 7e-44, bitscore:
                     145.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPLDFHVFDTTLRDGAQREGVSYSVADKLAVARLLDEIGVGFI
                     EGGWPGALPKDTEFFARARTELKLRHAQLVAFGSTRKAGVRVEDDAQVRALLDAETPVV
                     CLVAKSDVRHVREALRTTLEENLAMVRDTVAFLVGHGRRVFVDCEHFFDGYAADPDHGV
                     EVLRTAFAAGAEVGVLCDTNGGMLPMGVGRVVADVRARVEGRLGIHCQDDTGCAVANTL
                     AAVEAGVTHVQGTANGYGERAGNADTFVLIANLVTKMGLPVVPEGCLTELQRVSHAIAE
                     LANIAPDEHQPYVGASAFAHKAGLHASAIKVSPELYNHLDPELVGNDMRILVTEMAGRA
                     SVELKGRELGVDLDGHTDVIGRVVDRVKVLEADGWSFEAADASFELLLRAELPDAPPPL
                     FELESYRTSVEHWGNGQVMSEATVKVHVDGQRVISTGEGNGPVNALDNALRQALVSRYP
                     QLADVSLADYKVRILGWKGGSGATTRVLIDSTDGVGEWTTVGVHDNIVEASWHALVDAL
                     TYAVRNR"
     misc_feature    complement(11529..11542)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            11844..13340
                     /locus_tag="BLS21_RS00655"
                     /old_locus_tag="SAMN05660642_00131"
     CDS             11844..13340
                     /NRPS_PKS="Domain: AMP-binding (32-397). E-value: 5.6e-99.
                     Score: 323.4. Matches aSDomain:
                     nrpspksdomains_BLS21_RS00655_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014378292.1"
                     /locus_tag="BLS21_RS00655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00131"
                     /product="AMP-binding protein"
                     /protein_id="WP_245699874.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-79, bitscore:
                     262.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHPFDRSGTEVGPDGVRRYTRLPRNLVTMLRTAVDAHPDAEALV
                     ELGGERVTYRQLWNRATRVAGGLRAAGVQPGDRVANRLGNGNDWVYAFWGTLLAGAVAV
                     PVNTRFADPEVRYVLEDSGAAYAIEPGAALPDGEPLEVTEQGHTDLAAIFYTSGTTGFP
                     KGAMTTHENFLSNVETCLRCLSLDRQQLTTLISVPLFHVTGCNSQLLVVTATGGRAVVM
                     PVFEVRAFLRAIADERVDVLTTVPAIYWLALQQPDFADVDTSSVRALSYGGAPIAPDLV
                     HRIKEAFPTARVGNGFGLTETSSVSTYLPDEYAAEHADSVGFPAPVVDLDLADADPGTG
                     VGELLIRGPNVVAGYWRKPVQTAESFVDGWLHSGDLARIDDEGLVYVVDRKKDMINRGG
                     ENVYCVEVENALAAHPAVGEVAVVGVADPMMGEKVGAVVVPLPGRALDPDDLVAFARER
                     LADFKVPQYLSVRSEPLPRNPGGKVLKPPLREQGDWQPVR"
     aSDomain        11940..13034
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS21_RS00655_AMP-binding.1"
                     /evalue="5.60E-99"
                     /label="BLS21_RS00655_AMP-binding.1"
                     /locus_tag="BLS21_RS00655"
                     /protein_end="397"
                     /protein_start="32"
                     /score="323.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TAVDAHPDAEALVELGGERVTYRQLWNRATRVAGGLRAAGVQPGD
                     RVANRLGNGNDWVYAFWGTLLAGAVAVPVNTRFADPEVRYVLEDSGAAYAIEPGAALPD
                     GEPLEVTEQGHTDLAAIFYTSGTTGFPKGAMTTHENFLSNVETCLRCLSLDRQQLTTLI
                     SVPLFHVTGCNSQLLVVTATGGRAVVMPVFEVRAFLRAIADERVDVLTTVPAIYWLALQ
                     QPDFADVDTSSVRALSYGGAPIAPDLVHRIKEAFPTARVGNGFGLTETSSVSTYLPDEY
                     AAEHADSVGFPAPVVDLDLADADPGTGVGELLIRGPNVVAGYWRKPVQTAESFVDGWLH
                     SGDLARIDDEGLVYVVDRKKDMINR"
     CDS_motif       12294..12353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS21_RS00655_0001"
                     /evalue="1.70E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="BLS21_RS00655"
                     /protein_end="170"
                     /protein_start="150"
                     /score="20.5"
                     /tool="antismash"
                     /translation="AAIFYTSGTTGFPKGAMTTH"
     CDS_motif       12864..12941
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS21_RS00655_0002"
                     /evalue="3.70E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="BLS21_RS00655"
                     /protein_end="366"
                     /protein_start="340"
                     /score="28.9"
                     /tool="antismash"
                     /translation="VGELLIRGPNVVAGYWRKPVQTAESF"
     gene            complement(13508..14530)
                     /locus_tag="BLS21_RS00660"
                     /old_locus_tag="SAMN05660642_00132"
     CDS             complement(13508..14530)
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950057.1"
                     /locus_tag="BLS21_RS00660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00132"
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_091212536.1"
                     /transl_table=11
                     /translation="MRLAVIPGDGIGPEVVAEGLKVLRAVAPDVESTPYDLGASRWQRT
                     GELLPDTVLDELRQHDGILLGAIGDPSVPPGILERGLLLRLRFELDHHVNLRPARLFDG
                     VRSPLAGPGAIDMLCVREGTEGPYVGNGGVLRRDTPHEVATEVSLNTAFGVERVVRYAF
                     ERAVARPRKHLTLIHKTNVLTHAGSLWSRTVEEVSAEFPEVTVAYQHVDAASMFFVTDP
                     GRFDVIVTDNLFGDIVTDLAAAVTGGIGLAASGNLDASGTNPSMFEPVHGSAPDIAGTG
                     VADPTATVLSVGLLLEHLGRADQARKVNAAVAFDLSTRDPQAPVRTQEVGDRLAALAGG
                     "
     gene            complement(14547..16148)
                     /gene="serA"
                     /locus_tag="BLS21_RS00665"
                     /old_locus_tag="SAMN05660642_00133"
     CDS             complement(14547..16148)
                     /EC_number="1.1.1.95"
                     /GO_function="GO:0004617 - phosphoglycerate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950058.1"
                     /locus_tag="BLS21_RS00665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00133"
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="WP_091212538.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.3e-63, bitscore:
                     208.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAPVVLIAEELAPSVLEVLGRDVEIRHVDGADRAALLPALAD
                     AAAVMIRSATQIDAEALAAAPNLKVVARAGIGLDNVDVSAATERGVMVVNAPTSNIVSA
                     AEHAVALLLAAARHIPAADASLREGTWKRSKFTGVEVTDKVLGVVGLGRIGQLVAQRLA
                     AFGVTLIAYDPYIQPGRAAQLGVRMVSLEELLREADFITIHLPKTPETLGLIGAAELAT
                     TKRGVIIVNAARGGLVDEAALADALKSGQVGAAGIDVYAKEPCTDSPLFELPNTVVTPH
                     LGASTTEAQDKAGTAVAHSVRLALQGEFVPDAVNVQAGGVVAEDVRPGLPLAEKLGRVF
                     TAVAGGLAQSVTVEVRGKIAEFDDSVVQLAVLKGVFSDVVEEQVTYVNAPLFAQQRGLE
                     VALTSEVESPDYRNLITVRGAMADGTEVTVSGTLFGKNQVPKLVEVNGFDMDLDASGYL
                     LFFVYTDRPGVVGTVGAALGEAGINIAGAQVSRTTRGGEALMAVTVDSPVPAELLGDIA
                     GRIGAREARSADLTPR"
     gene            16309..17079
                     /locus_tag="BLS21_RS00670"
                     /old_locus_tag="SAMN05660642_00134"
     CDS             16309..17079
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS21_RS00670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05660642_00134"
                     /product="hypothetical protein"
                     /protein_id="WP_091212540.1"
                     /transl_table=11
                     /translation="MSTHDDERGSGTDPRYTPPQQYGQPPHQSGQPYGGQQYQPSPFGQ
                     GQPPGQPGYAQQYGQPGYPQQYGQPGGYNPYSPQGQYGQYGQYGQTAVPARPTPVVVAA
                     VLGFVFGAFGALMSLGLLLGGAVFGTVFEDLVASDPAFEDVDTGGVDTGQITGVLVVLG
                     ILALVWTVLMIWGAVRALTGRSRVLLLVGGAIAVAVTALFLVGVLSGVSTGGAGGGEVV
                     FSLLLFLAALAIVVLLCLRPAAQYFAAHRARRGR"
     gene            17100..17504
                     /locus_tag="BLS21_RS00675"
                     /old_locus_tag="SAMN05660642_00135"
     CDS             17100..17504
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS21_RS00675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05660642_00135"
                     /product="hypothetical protein"
                     /protein_id="WP_091212542.1"
                     /transl_table=11
                     /translation="MSPTDRAGTRRPPHVLMAAVAGSVEAFLLLLAALLYFTYSAFGPW
                     LAVFGAVFLGLAIACVVGSVLALRGRTPRVLMVAAATAAAIAVVLIAISVAGGAGFDAF
                     SAAVVLLGVGPVVLLLQAPSREWFAASRDR"
     gene            complement(17622..18650)
                     /gene="ilvC"
                     /locus_tag="BLS21_RS00680"
                     /old_locus_tag="SAMN05660642_00136"
     CDS             complement(17622..18650)
                     /EC_number="1.1.1.86"
                     /codon_start=1
                     /gene="ilvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014377555.1"
                     /locus_tag="BLS21_RS00680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00136"
                     /product="ketol-acid reductoisomerase"
                     /protein_id="WP_091212545.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.8e-07, bitscore:
                     25.4, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAEIFYDDDADLSIIQGRTVAVIGYGSQGHAHALSLRDSGVDVR
                     VGLPEGSKSRPKAEAEGLRVVTPADAAAEADLIMILVPDHVQRRVYAESVEPNLQDGDA
                     LFFAHGFNIRFGYIKPPAGVDVAMVAPKGPGHLVRREFENGKGVPALVAVEQDASGQAL
                     QLALSYAKAIGGARAGVIKTTFAEETETDLFGEQAVLCGGASALITAGFETLTEAGYQP
                     EIAYFECLHELKLIVDLMYEGGIAKQRWSVSDTAEYGDYTSGPKVIDQHVKDAMKDVLA
                     RIKDGSWAAEFIADQDAGAPDFKRRRAEAEAHPIEETGRKLRGLMSWVSTSDDYTGTAA
                     RS"
     gene            complement(18748..19275)
                     /gene="ilvN"
                     /locus_tag="BLS21_RS00685"
                     /old_locus_tag="SAMN05660642_00137"
     CDS             complement(18748..19275)
                     /EC_number="2.2.1.6"
                     /GO_function="GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925060.1"
                     /locus_tag="BLS21_RS00685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00137"
                     /product="acetolactate synthase small subunit"
                     /protein_id="WP_091212547.1"
                     /transl_table=11
                     /translation="MSRHTLSVLVENKSGVLARVSALFSRRGFNIESLAVGPTENPDLS
                     RMTIVADAESQPLEQITKQLNKLVEVIKIVELEAEAAVQRELLLVKVRAPMADRTQVLQ
                     TAELFRARVVDVNTDTVTLEATGTPDKLQALLAVLAPLGIKEMAQSGTVALGRGPRSMS
                     GAGTLRPVERTA"
     gene            complement(19391..21262)
                     /locus_tag="BLS21_RS00690"
                     /old_locus_tag="SAMN05660642_00138"
     CDS             complement(19391..21262)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003984 - acetolactate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012950063.1"
                     /locus_tag="BLS21_RS00690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05660642_00138"
                     /product="acetolactate synthase large subunit"
                     /protein_id="WP_091212550.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.9e-55, bitscore:
                     180.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.5e-50, bitscore:
                     163.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTTPGGSATREAAEALTGVETTARSVEEAAAEPLTGITGAQSL
                     VRSLEAVGVEVVFGIPGGAILPAYDPLFDSRVRHVLVRHEQGAGHAAQGYAQATGRVGV
                     CMATSGPGATNLVTPLADAYMDSVPIVAITGQVPSAAIGTDAFQEADIRGITMPITKHN
                     FLVTNAAEIPQRIAEAFHLAATGRPGPVLVDISKDALQATTDFSWPPRLDLPGYKPTTR
                     PHGKQVREAAALIAAARRPVLYVGGGVIKAQASAELAELVELTGAPVVTTLMARGAFPD
                     SHPQNLGMPGMHGNVTAVTALQKADLLVALGARFDDRVTGQLSSFAPGAKVVHADIDPA
                     EIGKNRKADVPIVGDARETIAELVTALRAERDAGRAPDLSAWWAQLDQWRQKYPLGYDW
                     PEDGALSPQYVIERLGAIAGPDAIYASGVGQHQMWAAQFIKYEKPGTWLNSGGLGTMGY
                     AVPAAMGAKYGCPDTTVWAIDGDGCFQMTNQELATCAIEGIPVKVALINNGNLGMVRQW
                     QTLFYEGRYSNTKLHPVDAEGRPTPVRIPDFVALAEALGCVGLRCESKDDVDAVIEKAM
                     AIDDAPVVIDFIVGADAQVWPMVAAGASNDDILAARDVRPVFGDGQV"
ORIGIN
        1 gcgcgttgac caggtgggca ccggtgccga accggcgccg catgaactcc gggacgctgc
       61 gcaccttcga cccgtagtag aagggcatca tcaccacgcc caggaacagc atggcaggga
      121 ccgcgccgac ccagaagtag tgcatggtcg gcatgccgaa ctgcgcgccg ttggcggaca
      181 tgccgatgat ctcgaccgca ccgaggttgg ccgagatgaa ggccagcccg gtcacccacg
      241 cgggcagcga ccggcccgac aggaagaagt cgaggctgtc ggagacccgc cggcgcgcgg
      301 ccagaccgat catgagcacg accgcgaagt agacgacgac cagcaggtag tcgacgaacg
      361 aggcgtcgag gcggagcgca tccacgggtc gggacctcct gtgggggcgt gtgggtcagg
      421 cgaggcgccg ggcgcctgcg gacggcacga ccgcgaaggc ccgcggagcc gtgaagccct
      481 gctgcgcgaa gcggtcggtg atcgcccgcg ccacgccgcc ggtgcggtcg gcgtcgacca
      541 gcaccacggc gctgccaccg aagccgccgc cgaccatccg ggcgccggcg gcgccggcct
      601 ccagcgcggt gtccacggcg gtgtcgagct cgaccgtgga gatctggaag tcgtcgcgca
      661 gcgaggcgtg cccggcggtg agcaccggcc cgatcgcgcc ggggtcggcg gtctcgcgca
      721 ggatccgcac gacctcgagg acgcgggcgt tctcggtgac gatgtgccgc gcgcgccgca
      781 gcagcacctc gccctcggag gtgccgtcgt ccagcggggc cagcgcggcc acgtccggga
      841 cgtcgcgcag ggcgcgcacg ccgagccgct cggcggcctg ctcgcactcg cggcgccggt
      901 cgccgtagcc gccggtggcg tggtcgtgcg tcgtcccggt gtcgacgacg agcagctcca
      961 gcccggccgc ccgcaggtcc agcggcacct gctcggtgct gcggtcgcgg gtgtcgagga
     1021 acagcgcgtg cccggcggtg cacagcagcg aggcggactg gtcgaggatg ccggtgggcg
     1081 cgcccacgaa gtcgttctcc gcccgccgtg ccacgtcgac caggtcggcg acggcgaggt
     1141 cgggggcggc gaggtcccgc agcgccagcg cgaccgagca ggacagcgcg gcggacgacg
     1201 acagccccat gccggccggg acgtcgccgt cgacgaggac gctcaccccg ccgggcacgc
     1261 ggtcgcgcag cgcgtcgacg acgccggccg ggtagcccgc ccagccaccg ggccgcccgg
     1321 gcgcgagctc ggtgaccggc acctccaccc ggtcgtcggg gtgctgtgcg gagacgaggg
     1381 cgaccagccc gtcgtcccgg cgggcgaccg cggcgcgcgt ggtctgcggc agcgccaccg
     1441 gcagcacgaa gccgtcgttg tagtcggtgt gctcgccgat gacgttcacc cggcccggtg
     1501 cggcccagac cccttcgggc ggcccgccga acgcctcggc gaacgccttc cgggccacgt
     1561 ccgccgccgt cactgcgccg tccccacgtt cctcagctgc tcggcgacgt cctccgggac
     1621 cgtgtcggtg atgaaggcgc ccatgccgga ctccgacccg gccaggtact tcagcttccc
     1681 gggcgcccgg cgcaacgaga acagctgcag gtgcagccac cagtcctcgc gcccgcggcc
     1741 gaccggggcc tggttccagg aggcgatgta gggcatcggg gtgtcgaagc ggtgggcgaa
     1801 gcggcccagc acgtcgaggt agatctcggc cagggcgtcg cgctccgcgg ccgtgagcgc
     1861 gggcaggtcg ggcacccggc ggtgcgggaa gacctgcagc tcgtagggcc agcgggcggc
     1921 ggccggcacg aacgccgtcc agtgctcgtt ggcggtgacc acgcggggcc cggcgcgctc
     1981 ggccgtgagc acgtcggcga acaggtcgcc gccggtctcc cgccggtgcc gctcgaccga
     2041 ggccagcacc ttctccaccc gcggcgtcac gaacgggtag gcgtagatct gcccgtgcgg
     2101 gtgggagagg gtcaccccga tctcctcgcc ggagttctcg aagacgaaga cctgcccgat
     2161 cccgtcgacg gccgacagct cggcggtgcg ctcggcccac acgtcgacga ccagccgggc
     2221 ccggtcggcg ccgagcgtgg cgaaggaccg gtcgtgctcg ctggtgaaga ccacgacctc
     2281 gcagcggccg aagccggggc gcagctcggt cagcggggcg ccgggcgcgg tcggggggac
     2341 gtcgcgctcg acggccgtcg ccagggacgg gaagcggttc tcgaagacga cgacctggta
     2401 gtcggcctcg gggacctcgg tgggttcgcg gccgggccgg gtcgggcaga gcgggcagag
     2461 gtccgccggg ggcaggaagg tccgcgtctg ccggtgcgag gccaggacga cccactcgcc
     2521 gagcagcggg tcccggcgca gctgcgagcg ggtgctgacc gggggcaggt cacgggggtc
     2581 ctcggcggtg cgcggcggcg cggtgtcccc ggcgtcgaag tagaggatct cccggccgtc
     2641 ggccagccga cgactcgtcc ggatcacggg tgggacctgc cttcccgccg ctcgtgactg
     2701 tgcgtgagcg gcgtcccgac gctagacccg ccccagcgac ccggccactc cggcggcccc
     2761 ggggacgacg agagcccccg gtcgggtgac cgggggctct cgctcgctgt agccccgaag
     2821 ggattcgaac cctcgctacc gccgtgagag ggcggcgtcc tgggccgcta gacgacgggg
     2881 ccgagcacgc ccatggtgcc atgtgccgtc cggggcccgc gcaccggggt gggcgccccc
     2941 ggagacgacg agagcccccg gtcgggtgac cgggggctct cgctcgctgt agccccgaag
     3001 ggattcgaac cctcgctacc gccgtgagag ggcggcgtcc tgggccgcta gacgacgggg
     3061 ccgtgcgggt ggtgctgagg aagtgtgtct ccaggcagac gtcttcctcg ctggggtacc
     3121 aggactcgaa cctagactaa cggaaccaga aaccgtcggg ctgccaatta ccccataccc
     3181 caagggtggt gctgcacctc gcggcgctgc acaacaccat acccgatgcc cgggggtggt
     3241 ccgggcaccc cccacggtga cggtggtcgc aggtcgagcg cggcggtccg cacctccggc
     3301 cgcagccacc ggcgggtgcg cacgaccagg ccgacgtacg cggccatggc gagcaggtcg
     3361 atgagcacca cgagcacgcc ggtcccggcc gggacggcgt cggtggccac gccctccccc
     3421 agcgagccgg ccagcaggaa gaccaccacg ttgttgacgg cgtgcagcac gatcgccgcc
     3481 tcgaggccac ccgtgagcca gacgaccgcc gaggccgcca gcccgaaggc gaaccggtcc
     3541 aggaacgtcc agacgtcggg cggcaggtgg gccgccgaga acagcgcggc ggtcagcacc
     3601 gccgccacca ccgcgcccgc gcggggccgg cccacccacc cggcgatcgc ctggctgagg
     3661 tacccgcgga acacgtactc ctccgcggcc gactgcaacg gcgtggtcag cagcacgacg
     3721 agcagcagcc atccgaaccc gtcgaccggg ccggtggcct cccagtcccc ggccacgaag
     3781 cccagcagga cgctcagcag gagcccggca gcgagcgtgg gcagcgccag cagcgtgtac
     3841 ggcgccagca gccgccaccg cagccgggcc agcaccgacg acgaccagcc gatccgcatc
     3901 ccgtgcgcgg cggcccacga cagccacacg caggggatgg cgacgatcag cgagatgttc
     3961 gtgagcagca gcaggccggg gtcggtgagg tcggtcgggt cgatcgccgt ggggtccggc
     4021 agcgccccgg tcgcgaagcc ggcgacgaac accaccgcgg tcgccacgag ggtggcgacg
     4081 aggtagaccg cggtgaacag cagcaggccc agcagcggcc gccaccagtg ccagtcgcgc
     4141 gagcgcatgg cctgcaggta gtcgaccggt tcgtcgtgcg gcggggtgcc cggcggcagc
     4201 tgccaccgca tcccgggcgg gggcacccac ggcggcgcgg gaggcggccc ccacggcggg
     4261 gcggtgtgcg gccccggctg cagcggcacc ggtccgagcg gccacgggac cggaccggcc
     4321 gccgtccccg cggccggcgg cgcgtgcccg ccgtacagcg ccccggggac gtggggcggc
     4381 gcggcgtagg gcccggtcgg cggtggcccg gcgtagggct cgtcgtccgg cacggcccag
     4441 ccgggcggtc ccgctgcgct catccggtca cccggggacg gcggcccgcg ccgcggcgag
     4501 gcgggcgagg ctgcgctcgc gacccagcag ctcgatggac tcgtacagcg gcggcgacac
     4561 cgtgcggccg ctgacggcga cgcgcaccgg gccgaacgcc tggcgcggct tgcggcccag
     4621 cccctcgacg agcgcctccc tgagcgcggt ctcgatggcc ggcgtcgtcc actcgggcag
     4681 ctggcgcagc gcggcctgcg cggcgtcgag cacctcggcc gcctccgggc cggccagctg
     4741 cttggccgcg gccgccgggt cgatctcgac gtcgtccacg aacaggaaac cgagcagccc
     4801 cacggcgtcg gagaggacga tcatgcgctc ctgggccagc ggggcgatcg tctcgaggac
     4861 gcgccactgc tcggccgtcg gcggctccgc gaccagcccg gcgcgggcga ggaagggcac
     4921 cacccgctcg gtgaagtcct ccaccggcag cgcgcgcagg tgggtggcgt tgatcgcctc
     4981 ggccttcttc aggtcgaagc gggccgggtt ggcgctgacc cgggtgacgt cgaaggcctc
     5041 gaccatctcc tgcatcgaga agacgtcgcg gtcctcggcg atcgaccagc ccagcagggc
     5101 gaggtagttg gcgaagccct cggggacgaa gccgcgctcg cggtagacgt cgacgttgga
     5161 ctgcgggtcg cgcttcgaga gcttcctgtt gccctccccc gtcacgtagg ggaggtggcc
     5221 gaagcgcggc gcgccggagg cgacgccgat gtcggccagc gcgccgtaga gcgccagctg
     5281 ccgcggcgtg gagggcagca ggtcctcccc gcgcaggacg tcggtgatgc ccatcagggc
     5341 gtcgtccacc gggttgacga acgggtagag cggcaccccg ttggcccgga cgatgacgaa
     5401 gtcaggcacg gaaccggcgg cgaagcggat ctccccgcgg accaggtcgg tccaggcgag
     5461 gtcctcgtcg ggcatccgca gccgcagcac cggctcgcgg ccctcggcgc ggagggccgc
     5521 cttctgctcg tcggtgagga accggtcggc gttgtcgtag ccgagcttcg ggtcctgccc
     5581 cgcggccagc cggcgggcct cgacctcctc gttggtggag aaggactcgt aggcgtgccc
     5641 cgccgccagc agcttctggg cgacctcgcg gtagacctcg tgccgctcgg actgccggta
     5701 gggcccgtgc gggccgccga cctctgggcc ctcgtcccac tccaggccca gccagcgcag
     5761 gctgtcgagc aggtgccggt aggactcctc ggagtcgcgc gaggcgtcgg tgtcctcgat
     5821 gcggaagacg aacgtgccgc cggtgtgccg ggcgtgcgcc cagttgaaca gcgcggtccg
     5881 gagcaggccg acgtgcacca tgcccgtcgg cgacgggcag aaccgggtgc gggtcgtcgt
     5941 cggggcggtg ggcgggaggc cggtcgcggt caccgcaggc cgccggcggt ggaggcggtg
     6001 tcggcgccgc tgacaccgtt gaccagggaa cccaggccct cgatggcgca ctccacccgc
     6061 tggccgggcc ggatcgggcc cacgccgctg ggggtgccgg tgagcacgac gtcgccgggc
     6121 agcagggtca tcacctgcga gatgtaggag accagcgtcg ggatgccgaa gagcagctgg
     6181 ctggtgcggc cggactggcg cagctcgccg tccaccgtgc aggtgacctc caggtcggcg
     6241 gggtccttgc ccaggccggc gaggtcggtc tcgatccacg ggcccagcgg gcagaaggag
     6301 tcgaagccct tggcgcgggt ccactgcccg tcgctggcct gcatgtcccg ctcggtgacg
     6361 tcgttggcga tcgtgtagcc gaacacgctg cccagcgcct gctccggggt gacgtggcgg
     6421 gcgccgcggg cgccgatgac gacggccagc tcgacctcgt ggtggacgtt ggtgctgccc
     6481 ggtgggatgc ggatggcgtc gcccgggccg atgaccgtcg tcgacggctt gaggaacagc
     6541 agcggctgcg acggggcgtc gccggtgccc atctcctcga cgtgggccgc gtagttcttg
     6601 ccgacggcca ccaccttgct cggcaggatc ggcgagagca gccgcacgtc ggcctgcgcg
     6661 taacgctggc cggtgaagga gatggtgccg aacgggtggc cctcgatctg ggcgacctgg
     6721 ccgtcgccgt cgaggacgcc gaaggacatg cccgagggcg aggcgaagcg gacgatgcgc
     6781 acgccccgag gctagtcgcc gcttcgcgcg cgcccgtgcc gaggaggacc taccgtgccc
     6841 ccatggcctg ccgtttctcg gaactcgtgg tggacagccg cgatcccgag gcgctggcgg
     6901 ccttctgggc cgaggtcctc gggtacgagg tcctcggccg ggaggaggac ggcgccgtgg
     6961 agatcggtcc cgtcaccggc ttcggcggtc cggcgccgac gctcgtcttc gccccggtgg
     7021 ccgagccgac accggggaag gtgcggctgc acgtcgacgt cagccccacc gaccgcgacc
     7081 aggacgccga gctggcacgg ctgctcgcgc tgggagccac ccgggcggac gtgggccagc
     7141 gggagggtcg ggcgggtgag caggatgcag tgagctggta cgtgctggcc gatccggagg
     7201 gcaacgagtt ctgcctcctg cgccgccgcc tcgatccgct gtgaccgagt cctgacagag
     7261 gagaccgaca tgatcctgat cgtcatcaag atgcccgtcc ggcccgaccg catcgacgag
     7321 ttccggaccc acgccgacga gtacgcccgg gcggtgaacg ccgaggaggg cagcctgttc
     7381 ttcgagtggt cccgcagcgt cgaggacccc aacaccttcg tctgcatcga gggcttccgg
     7441 gactccgagg ccggcgcctc gcacgtcgcc accccgcacg ccaaggccgc gttcgactgg
     7501 atgtccgacc tggtcgccga acagccgcag atcatctaca tcgacgcccc ggaggtcagc
     7561 ggcttcggcc ccatgggcga ggtccagccc aggggctagc cgccgcgggt cgcggggggg
     7621 acgcgtcgtc ctccgcgcaa ccgctgctgc acctgcgaga gtgatcacgt gacccgcgct
     7681 ctcgcggtgc tgacgtgcct cgcgctgctc acggtcgtgg tcgaggcgac cgacgacccg
     7741 cgcccgctgc tcgccgtcgc cctcggcgtg acgttcgcgg cgcacgcgct cgtcgcgctg
     7801 ccctggctcg ccggtcagcc cgtgccccgc cggtactggc tgaccgccgg acacgtgtgc
     7861 ctgcagctcc ccctcggcgc gctgatgttc ggcgcggcgc acgccggggt gggggcgacc
     7921 ctgctgctgc tcgtgctggt cgcgcagagc gtgctgctcc tgccgctgcc ggccgccgcc
     7981 gtggtcacgg cactggtccc cctcgtgcac gccgggatgg gctgggccga cttcgcgcgc
     8041 aacggcctcg ggatgctggg cgcggcggtc ttcaccgcgg tcgtcaccgc actgctccag
     8101 cgggagcagc aggcccgagg cgagctggcc gaggcgaacg agcggctgcg cgggtacgcc
     8161 gcacaggccg aggagctcgc gaccacgcgg gagcgcaacc ggctggcccg cgacatccac
     8221 gacggcctcg gccaccacct gaccgtcgtg cagatgcagg tgcaggccgc gcgggccgtg
     8281 ctgccgtcgg accccggccg cgccgacgag gtgctcgcca aggcccagca gcaggccagc
     8341 gaggcgctgg ccgaggtccg ccggtcggtg gccacgctgc gcgagccccg gacgtcgccg
     8401 ccgctgcgcg ccgcgctcga ggcgctcacc gccgaggtct ccgcggccgg cgtccccgcg
     8461 acgctcgagg tcgtcggtac cgagcggcgg ctgcccgcgg aggccgagga gtccctgttc
     8521 cggtcggcgc aggaggggct gaccaacgtc cgcaagcacg cggcggcgac ctcggcccgg
     8581 gtgaccctga cctacggcga cgacgggacg gtgcggctga gcgtgcggga cgacggctgc
     8641 ggcctgcctg cgggtgcgca cgacgcggac ccgcgcggct tcgggctggt cgggttgcgg
     8701 gagcgggcgg cgcgcgccgg cgggcagctg gtcgtggcac cggtcccggg cgggggcacc
     8761 gagctgctgg tggaggtgcc gggatgagcg ccgtccgcgt gctggtggtc gacgaccagg
     8821 cgctgttccg cgaggcgttg gccacgctgc tgggcgcccg gcccgaggtc gaggtcgtcg
     8881 gggaggccgg gaacgggcac caggcgctgg agcgggcggc cgcgctgcag cccgacgtcg
     8941 tcctgatgga cctgcacatg ccggtgctcg acgggatcgc cgcgacccgg cggctcaagg
     9001 tcgagcagcc cggtgtgcgg gtgctggcgc tgacgacctt cgacgacgac gaggacgtct
     9061 tcgcggcgct gcgggccggc gcgctgggct acctgctcaa ggacgtctcc tccgaccgcc
     9121 tggtcgaggc ggtgctgtcg gcggcgcgcg gggagtcggt gctgcagccc tcggtcgcgg
     9181 cgaaggtggt ggcccgcttc gcgcagctgg acgacgcccc gcggtcccgg ccgcagccgc
     9241 tggtcgtgcc gctgtccgac cgcgagctcg acgtgctccg gctgctggcc gacggccgca
     9301 gcaaccggga gatcgcgacg gcgctgttcc tggccgaggg cacggtcaag aaccacgtga
     9361 ccaacgtgct gggcaagctc ggcgcccggg accgcaccca ggcggcgctg cgcgcccggg
     9421 ccctcgacct gctctgaggg gtcatgccgg gacgtgaccg gcgaccgtga cctccggcac
     9481 ctggcaggga cggcgcggcg tccgacgctc tccggcatga cgacgcagac ccctccccgg
     9541 cacgcgcaca gccgcggccg gcgcacctgg cacctcgtcc gccactacct cgagatggtc
     9601 gtcgcgatgg tggtcgggat ggcggtgctg ggcccggtcg aggccctcct ctggcccggc
     9661 gtggacgacc gggtcgacgt gcacgccgtg gtcatggcca ccaacatggc cgtcgcgatg
     9721 gccgcctgga tgcggttccg cggccactcc tggcccgcga tcgcggagat gtccgcggcg
     9781 atgtacgtgc cgttcgccgt cctgctggtg ccctactggg cgggcgcggt gtccggctcg
     9841 ttcctgttca ccgccgggca cgtgctgatg ctccccgcca tggcgctggc gatgtggtgg
     9901 cgcctcgacg agtacgccgg ctgctgagga caccgagagt gcgcggagga ggacctgtcc
     9961 aggacctgcg acaggtcctc ctccgcgcac tcgtgcggcg tcagcggttg cggacggcgt
    10021 aggtgagggc gtcgaccagg gcgtgccagg aggcctcgac gatgttgtcg tggacgccca
    10081 cggtggtcca ctcccccacc ccgtcggtgc tgtcgatcag cacccgggtc gtggcgccgc
    10141 tgccgccctt ccagcccagg atgcggacct tgtagtcggc cagcgagacg tcggccagct
    10201 gcgggtagcg gctgaccagc gcctggcgca gcgcgttgtc cagcgcgttg accgggccgt
    10261 tgccctcgcc ggtgctgatg acccgctgcc cgtcgacgtg caccttgacc gtggcctcgc
    10321 tcatgacctg gccgttgccc cagtgctcga cggaggtccg gtagctctcc agctcgaaca
    10381 gcggcggcgg tgcgtcgggc agctcggcgc gcagcagcag ctcgaaggag gcgtcggcgg
    10441 cctcgaacga ccagccgtcg gcctcgagca ccttgacccg gtcgacgacc cggccgatga
    10501 cgtcggtgtg cccgtcgagg tcgacgccga gctcgcggcc cttgagctcc accgacgccc
    10561 ggccggccat ctcggtgacc aggatgcgca tgtcgttgcc cacgagctcg gggtcgaggt
    10621 ggttgtacag ctcggggctg accttgatcg cgctggcgtg caggccggcc ttgtgcgcga
    10681 acgccgaggc gccgacgtag ggctggtgct cgtcgggggc gatgttggcc agctcggcga
    10741 tggcgtggct gacccgctgc agctcggtca ggcagccctc ggggacgacc ggcaggccca
    10801 tcttggtgac caggttggcg atcagcacga aggtgtcggc gttgccggcg cgctcgccgt
    10861 agccgttcgc cgtcccctgc acgtgggtga cgccggcctc gaccgcggcc agggtgttgg
    10921 cgacggcaca gccggtgtcg tcctggcagt ggatgcccag gcggccctcg acccgggcgc
    10981 ggacgtcggc gacgacccgg ccgacgccca tcggcagcat cccgccgttg gtgtcgcaca
    11041 ggaccccgac ctcggcgccc gcggcgaagg ccgtccgcag cacctcgacg ccgtggtcgg
    11101 ggtcggcggc gtagccgtcg aagaagtgct cgcagtcgac gaacacccgc cggccgtgcc
    11161 cgaccaggaa ggcgacggtg tcgcgcacca tcgcgaggtt ctcctcgagc gtcgtccgca
    11221 gcgcctcgcg cacgtgccgg acgtcggact tcgcgaccag gcagaccacc ggcgtctcgg
    11281 cgtcgagcag tgcgcgcacc tgggcgtcgt cctcgacgcg gacgccggcc ttgcgggtgg
    11341 agccgaacgc caccagctgg gcgtgccgca gcttgagctc ggtgcgggcg cgggcgaaga
    11401 actcggtgtc cttgggcagc gcgcccggcc acccaccttc gatgaagccg acgccgatct
    11461 cgtcgagcag ccgggcgacg gccagcttgt cggcgacgga gtagctcacg ccctcgcgct
    11521 gggcgccgtc gcgcagcgtg gtgtcgaaga cgtggaagtc gagcggggtg gacatcggat
    11581 ctcctgcggg tgggcggccc gaacaccaaa aagacccccc gggtacggga ggtcggcgcg
    11641 cggtcgggga ggggactgcg cgctacgtgc taatgagcga ggcgatggcg atcgagccgg
    11701 cggagtgcat cgccgtcgag taaagcacgc ccggacgtcc cgatcgaccg ccgccgtgcc
    11761 gtgcccaccg atggactccc ggggtgagcc ccgacacact gcccagcgca gggtcgcaga
    11821 cgacgtccca tcgggaggcc cgggtgcccc atccgttcga ccgcagcggt accgaggtcg
    11881 gccccgacgg cgtccggcgc tacacccggc tgccccggaa cctggtcacg atgctgcgca
    11941 cggcggtcga cgcgcacccc gatgcggagg cgctggtcga gctcggcggc gaacgggtga
    12001 cctaccggca gctgtggaac cgcgcgacgc gcgtcgccgg cgggctgcgg gccgcgggcg
    12061 tgcagccggg cgaccgggtc gccaaccggc tgggcaacgg caacgactgg gtgtacgcgt
    12121 tctggggcac gctgctcgct ggcgcggtcg ccgtcccggt gaacacccgc ttcgccgatc
    12181 ccgaggtgcg ctacgtcctg gaggactccg gtgccgcgta cgccatcgag cccggggccg
    12241 cgctgcccga cggcgaaccg ctggaggtga ccgagcaggg gcacaccgac ctggccgcga
    12301 tcttctacac cagtggcacc accggcttcc ccaagggtgc gatgaccacc cacgagaact
    12361 tcctgtcgaa cgtcgagacc tgcctgcgct gcctgtccct cgaccgccag cagctgacca
    12421 cgctcatctc ggtgccgctg ttccacgtca ccggctgcaa ctcccagctg ctggtggtca
    12481 cggcgaccgg cgggcgggcg gtggtcatgc cggtcttcga ggtccgcgcc ttcctgcgcg
    12541 ccatcgccga cgagcgcgtc gacgtgctca cgacggtgcc ggcgatctac tggttggcgc
    12601 tgcagcaacc ggacttcgcc gacgtcgaca cctcgtcggt gcgggcgctc agctacggcg
    12661 gggcgcccat cgcaccggac ctcgtgcacc gcatcaagga ggccttcccg accgcgcggg
    12721 tcggcaacgg cttcgggctg accgagacgt cgtcggtgtc cacctacctg cccgacgagt
    12781 acgccgccga acacgccgac tcggtgggct tcccggcgcc ggtggtcgac ctggacctcg
    12841 ccgacgccga tccggggacc ggtgtcggcg agctgctgat ccggggaccg aacgtcgtcg
    12901 ccggctactg gcgcaagccg gtgcagacgg cggagtcgtt cgtcgatggc tggctgcaca
    12961 gcggcgacct cgcccgcatc gacgacgagg gcctcgtgta cgtcgtcgac cgcaagaagg
    13021 acatgatcaa ccgcggtggc gagaacgtgt actgcgtcga ggtggagaac gccctggccg
    13081 cgcacccggc cgtgggcgag gtcgcggtcg tcggcgtcgc cgacccgatg atgggcgaga
    13141 aggtcggtgc cgtcgtcgtc cccctgcccg gccgggcact cgacccggac gacctggtcg
    13201 ccttcgcccg cgagcggctg gccgacttca aggtgccgca gtacctgtcc gtccgcagcg
    13261 aaccgctgcc ccgcaacccc ggcggcaagg tgctcaagcc gccgctgcgg gagcagggcg
    13321 actggcagcc cgtccgctga gagaggacca cccgaggaga tccgtgccca ccgtcgaggc
    13381 cgtccgtggc cccgttcggg tctctcggcg gcaacaccga tccgggctca ccgttgcggg
    13441 tccgggctca cgaccggtgg cgagcccgga ccccgggtga tcagctcagc tggtcatccg
    13501 ggggcgctca gccgccggcg agcgcggcga gccggtcgcc gacctcctgg gtgcgcaccg
    13561 gggcctgcgg gtcgcgggtg gagaggtcga aggcgacggc ggcgttgacc ttgcgggcct
    13621 ggtcggcgcg gccgaggtgc tcgagcagca ggccgaccga cagcaccgtg gcggtggggt
    13681 cggcgacccc cgtgccggcg atgtcgggtg ccgagccgtg caccggctcg aacatgctgg
    13741 ggttggtgcc cgaggcgtcg aggttgccgc tggcggccag cccgatgcca ccggtgacgg
    13801 ccgcggccag gtcggtgacg atgtcgccga acaggttgtc ggtgacgatg acgtcgaagc
    13861 ggcccgggtc ggtcacgaag aacatcgagg ccgcgtcgac gtgctggtag gcgacggtga
    13921 cctcggggaa ctccgcggag acctcctcga ccgtccgcga ccacagcgac ccggcgtggg
    13981 tgagcacgtt ggtcttgtgg atcagcgtca ggtgcttgcg cggccgggcg acggcccgct
    14041 cgaaggcgta gcggacgacc cgctcgacgc cgaacgcggt gttcaggctg acctcggtgg
    14101 ccacctcgtg cggggtgtcg cggcgcagga cgccgccgtt gcccacgtag ggcccctcgg
    14161 tgccctcgcg cacgcacagc atgtcgatgg cgccgggccc ggccagcggg ctgcggacgc
    14221 cgtcgaacag ccgggccggg cgcaggttga cgtggtggtc gagctcgaag cgcagccgca
    14281 gcagcaggcc gcgctcgagg atccccggcg ggacgctggg gtcgccgatg gcgccgagca
    14341 ggatcccgtc gtgctggcgc agctcgtcga gcaccgtgtc cggcagcagc tcgccggtgc
    14401 gctgccaccg cgacgcgccg aggtcgtagg gggtgctctc gacgtcgggc gcgaccgcgc
    14461 ggaggacctt gaggccctcg gccaccacct ccggaccgat tccgtctcca gggatcacag
    14521 ccaggcgcat ggggacagac cctaggtcag cgcggggtga ggtccgcgga gcgggcctca
    14581 cgcgcgccga tccggccggc gatgtcaccc agcagctcgg ccgggaccgg gctgtcgacg
    14641 gtcaccgcca tgagcgcctc gccgccgcgg gtggtgcggc tgacctgcgc gccggcgatg
    14701 ttgatcccgg cctcccccag cgccgcgccg accgtgccga cgacgccggg ccggtcggtg
    14761 tagacgaaga acagcaggta gcccgacgcg tccaggtcca tgtcgaagcc gttgacctcg
    14821 accagcttgg gcacctggtt cttgccgaac agggtgccgg agacggtcac ctcggtgccg
    14881 tcggccatcg cgccgcggac ggtgatcagg ttgcggtagt cggggctctc gacctcgctg
    14941 gtcagcgcca cctcgaggcc gcgctgctgg gcgaacagcg gggcgttgac gtaggtgacc
    15001 tgctcctcga ccacgtcgga gaacacgccc ttgaggacgg cgagctgcac caccgagtcg
    15061 tcgaactcgg cgatcttgcc gcggacctcg acggtgaccg actgggccag cccgcccgcg
    15121 acggcggtga acacccggcc gagcttctcg gccagcggca ggcccgggcg gacgtcctcg
    15181 gcgacgaccc cgccggcctg gacgttcacc gcgtcgggca cgaactcgcc ctgcagcgcc
    15241 agccgcaccg agtgcgccac ggcggtgccg gccttgtcct gcgcctcggt cgtggaggcg
    15301 cccaggtgcg gggtgacgac ggtgttcggc agctcgaaca gcgggctgtc ggtgcacggc
    15361 tccttggcgt acacgtcgat gcccgccgcg ccgacctggc ccgacttcag cgcgtcggcc
    15421 agcgccgcct cgtcgaccag cccgccgcgg gcggcgttga cgatgatcac gccgcgcttg
    15481 gtggtggcga gctcggcggc gccgatgagg cccagggtct ccggcgtctt gggcaggtgg
    15541 atcgtgatga agtccgcctc gcgcagcagc tcctccagcg acaccatgcg gacgccgagc
    15601 tgggcggccc ggcccggctg gatgtagggg tcgtaggcga tgagcgtgac gccgaaggcg
    15661 gccagccgct gggcgaccag ctggccgatc cgccccaggc cgaccacgcc gaggaccttg
    15721 tcggtgacct cgacgccggt gaacttggag cgcttccagg tgccctcgcg cagcgacgcg
    15781 tcggcggccg ggatgtggcg cgcggcggcc agcagcaggg ccaccgcgtg ctcggcggcg
    15841 ctgacgatgt tcgaggtcgg ggcgttgacc accatgaccc cgcgctcggt cgccgcggac
    15901 acgtcgacgt tgtccaggcc gatgccggcg cgggcgacga ccttgaggtt cggggcggcg
    15961 gccagcgcct cggcgtcgat ctgcgtggcg ctgcggatca tcaccgcggc ggcgtcggcc
    16021 agcgcgggca gcagggcggc gcggtcggcg ccgtccacgt gacggatctc gacgtcacgc
    16081 cccagcacct ccagcacgct gggagcgagt tcctcggcga tcaggacgac gggcgcggtc
    16141 gtggtcacgg gaccacagcc tagggagcag cgcggccccg ggcccaccag ccccttcccg
    16201 tggcgatcgg cgatcccccg ccgaggggtg gggtcgcttg cccgggtggg gacggccgga
    16261 catcctggcc gggacggtcg gcggacgccg gcgccgacgg aggagaccat gagcacccac
    16321 gacgacgagc gcggctccgg cacggacccc cggtacacgc ctccgcagca gtacggtcag
    16381 ccgccccacc agtccgggca gccgtacggg ggccagcagt accagccctc ccccttcggc
    16441 cagggccagc cgcccggcca gcccgggtac gcgcagcagt acggccagcc ggggtacccc
    16501 cagcagtacg gccagccggg cggctacaac ccgtactcgc cgcagggcca gtacgggcag
    16561 tacggccagt acgggcagac ggcggtgccc gcgcgcccca cgccggtcgt ggtcgccgcc
    16621 gtcctcggct tcgtcttcgg cgccttcggc gcgctgatgt ccctgggcct gctcctgggc
    16681 ggcgcggtgt tcggcaccgt cttcgaggac ctggtcgcca gcgacccggc cttcgaggac
    16741 gtcgacaccg gcggggtcga caccggtcag atcaccggcg tgctcgtggt cctggggatc
    16801 ctcgccctgg tctggaccgt gctcatgatc tggggcgcgg tgcgcgcgct gaccggtcgc
    16861 agccgcgtgc tgctgctggt gggcggggcg atcgccgtgg cggtgaccgc gctgttcctg
    16921 gtcggcgtcc tctcgggcgt gtcgaccggc ggggccggtg gcggcgaggt cgtcttctcc
    16981 ctgctgctgt tcctagcggc cctggcgatc gtcgtgctgc tgtgcctgcg gccggccgcg
    17041 cagtacttcg ccgcgcaccg cgcgcggcgc ggccgctgac gccgggccgg gggcgccccg
    17101 tgtccccgac cgaccgggcc ggcacccgac ggccgccgca cgtcctcatg gcggcggtcg
    17161 ccggctcggt cgaggccttc ctgctgctgc tggccgccct gctctacttc acctacagcg
    17221 cgttcggccc gtggctggcc gtcttcggtg cggtgttcct cggcctggcg atcgcctgcg
    17281 tcgtcggcag cgtgctggcg ctgcgcggcc ggacgccccg cgtcctgatg gtcgccgcgg
    17341 cgacggcggc cgcgatcgcc gtggtcctca tcgcgatctc ggtcgccggc ggggcgggct
    17401 tcgacgcctt ctcagcggcg gtcgtgctgc tcggcgtggg acccgtcgtc ctgctgctgc
    17461 aggcgccgtc ccgggagtgg ttcgccgcct cccgcgaccg atgagccgcc ggacgacgag
    17521 gcccccgccg ccgatcggcg gcgggggccc ggaggatgcc gtcggccccg tcccgggccc
    17581 cgccctgagc ctgcgaaggg tggggaggac ggggtcccct ctcagctccg tgcggcggtg
    17641 ccggtgtagt cgtcggacgt cgacacccag ctcatcaggc cgcgcagctt gcgcccggtc
    17701 tcctcgatcg ggtgcgcctc ggcctcggcc cggcggcgct tgaagtccgg cgcaccggcg
    17761 tcctggtcgg cgatgaactc cgccgcccac gagccgtcct tgatccgggc caggacgtcc
    17821 ttcatggcgt ccttgacgtg ctggtcgatg accttcgggc cggaggtgta gtcgccgtac
    17881 tcggcggtgt cggacaccga ccagcgctgc ttggcgatgc cgccctcgta catgaggtcg
    17941 acgatcagct tcagctcgtg caggcactcg aagtaggcga tctcgggctg gtagccggcc
    18001 tcggtgaggg tctcgaaccc ggcggtgatc agcgcgctgg cgccgccgca gagcacggcc
    18061 tgctcgccga acaggtcggt ctcggtctcc tcggcgaagg tcgtcttgat gacgccggcg
    18121 cgggcgccgc cgatggcctt ggcgtaggac aacgccagct gcagggcctg gccgctggcg
    18181 tcctgctcga cggcgaccag cgccggcacg cccttgccgt tctcgaactc gcggcgcacg
    18241 aggtgaccgg ggcccttggg ggcgaccatg gcgacgtcga cgccggccgg gggcttgatg
    18301 tagccgaacc ggatgttgaa gccgtgggcg aagaacagcg cgtcgccgtc ctgcaggttg
    18361 ggctcgaccg actcggcgta caccctccgc tgcacgtggt ccgggaccag gatcatgatc
    18421 aggtcggcct cggcggcggc gtcggccggg gtcacgaccc gcagcccctc ggcctcggcc
    18481 ttgggccggc tcttgctgcc ctcgggcagg ccgacgcgga cgtcgacgcc cgagtcgcgc
    18541 agcgacagcg cgtgggcgtg gccctggctg ccgtagccga tgacggcgac ggtgcgcccc
    18601 tggatgatcg acaggtcggc gtcgtcgtcg tagaagatct cggcggccat gtgctgtgcg
    18661 gttccttccg gtggtgtggt gtgtggcccc tctgcagggt cccgccgcga gcctgcgagt
    18721 ggcgggggca gaggggtcct tctgccttca ggcggtgcgc tcgaccgggc gcaaggtacc
    18781 ggcgccgctc atcgagcgcg gaccccggcc cagggcgacc gtgcccgact gcgccatctc
    18841 cttgatgccc agcggggcga ggacggcgag cagggcctgg agcttgtccg gcgtgccggt
    18901 ggcctccagg gtcacggtgt cggtgttgac gtcgacgacg cgggcgcgga acagctcggc
    18961 ggtctgcagc acctgggtgc ggtcggccat cggcgcgcgc accttgacca gcagcagctc
    19021 gcgctggacg gcggcctcgg cctccagctc gacgatcttg atgacctcga cgagcttgtt
    19081 cagctgcttg gtgatctgct ccagcggctg gctctcggcg tcggcgacga tcgtcatccg
    19141 ggacaggtcc gggttctcgg tcggcccgac ggcgagggac tcgatgttga agccgcgccg
    19201 gctgaacagc gccgagacgc gcgccaggac accggacttg ttctcgacca ggaccgacag
    19261 ggtgtggcgg gacattgctc aacttccttt caggaccgac cggctccggg tggcccccca
    19321 gggtcccctc ccgagcctgc gaggggtggg gaggaggggg tccttcgccg agcggtgggg
    19381 gaagggggtc ctagacctgg ccgtcgccga agaccgggcg gacgtcccgc gcggccagga
    19441 tgtcgtcgtt gctggcgccc gcggccacca tcggccacac ctgggcgtcg gcaccgacga
    19501 tgaagtcgat gaccaccggg gcgtcgtcga tggccatcgc cttctcgatg acggcgtcga
    19561 cgtcgtcctt gctctcgcag cgcaggccga cgcagcccag cgcctcggcc agcgccacga
    19621 agtcggggat gcgcaccggc gtgggccggc cctcggcgtc gaccgggtgc agcttggtgt
    19681 tggagtagcg gccctcgtag aagagggtct gccactggcg gaccatgccg aggttgccgt
    19741 tgttgatgag ggcgaccttg accgggatcc cctcgatggc gcaggtggcc agctcctggt
    19801 tggtcatctg gaagcagccg tcgccgtcga tggcccacac ggtggtgtcc gggcagccgt
    19861 acttggcgcc catcgccgcg ggcacggcgt agcccatcgt cccgaggccg ccgctgttga
    19921 gccacgtgcc gggcttctcg tacttgatga actgggcggc ccacatctgg tgctggccga
    19981 caccggaggc gtagatcgcg tccggcccgg cgatcgcgcc cagccgctcg atgacgtact
    20041 gcggcgacag cgcgccgtcc tcgggccagt cgtagccgag cgggtacttc tggcgccact
    20101 ggtccagctg ggcccaccag gcggacaggt cgggcgcgcg gccggcgtcg cgctcggcgc
    20161 gcagcgcggt gaccagctcg gcgatggtct cccgcgcgtc cccgacgatg ggcacgtcgg
    20221 ccttgcggtt cttgccgatc tcggccgggt cgatgtcggc gtgcacgacc ttggccccgg
    20281 gggcgaacga cgacagctgg ccggtgaccc ggtcgtcgaa gcgggcgccg agggcgacga
    20341 gcaggtcggc cttctgcagc gcggtgaccg cggtgacgtt gccgtgcatg ccgggcatcc
    20401 cgaggttctg cgggtggctg tcggggaacg cgccgcgcgc catgagggtg gtgaccacgg
    20461 gggcaccggt gagctcgacc agctcggcca gctcggcgct cgcctgcgcc ttgatgaccc
    20521 caccaccgac gtagagcacc ggccggcggg cggcggcgat cagcgcggcg gcctcgcgga
    20581 cctgcttgcc gtgcgggcgg gtggtcggct tgtagccggg caggtccagc cgcggcggcc
    20641 acgagaagtc ggtggtggcc tgcagcgcgt ccttggagat gtcgaccagc accggcccgg
    20701 ggcggccggt ggcggcgagg tggaaggcct cggcgatccg ctgcgggatc tcggcggcgt
    20761 tggtgaccag gaagttgtgc ttggtgatcg gcatcgtgat gccgcggatg tcggcctcct
    20821 ggaaggcgtc cgtgccgatc gccgcactcg ggacctgacc ggtgatcgcc acgatcggga
    20881 ccgagtccat gtaggcgtcg gccagcgggg tcaccaggtt ggtcgcgccg gggccggagg
    20941 tggccatgca gacgccgacc cggccggtgg cctgggcgta gccctgcgcg gcgtgcccgg
    21001 cgccctgctc gtgccggacg agcacgtgcc gcaccctcga gtcgaacagc gggtcgtagg
    21061 cgggcaggat cgcgccgccc gggatgccga agacgacctc gacgccgacc gcctcgagcg
    21121 accgcacgag gctctgcgcc ccggtgatgc cggtgagggg ctcggcggcg gcctcctcga
    21181 ccgagcgggc ggtggtctcg acccccgtca gtgcctcggc ggcctcgcgg gtggcggacc
    21241 cacccggggt ggtgctggtc atggcgtctc ctggccgtgc gtctcgctgg tcgggccttg
    21301 ctgggcgccc cgggaacggg gccgtcgatc ggtgccgtgc ggtggtcggc ggtacctgcg
    21361 gcgcgggccg gcggcgtcgg aggaggtcgg ggcccgcaaa cgaaagaccc ctcgtgcctg
    21421 caggcacaga ggggtcagcg cgtcggtcgg gagggaccga cgcgctaggc gattacgagg
    21481 agcaggcagg ccgggcgcac acggccactg tgcgcctcgt ccaggcccgt cgtcaaccag
    21541 gccgtctcat tgagtgggaa cgcgtgtcgt cagacgtggg acggcgtgcg gtcgccgtcc
    21601 agcgcgcccc cgactggccc gacgagcacc gcggccaggt cggcgaccgg caccgggcgg
    21661 ccgagcaggt ggccctgcag gaaccggcag cccagccggc gcagcgccgc gagctgcccg
    21721 ggcgtctcca cgccctcggc gacgacgtcc atgccgagcg tgcggcccag gtcgacgacg
    21781 ctggcgacga cggccgccgc gcgcgggtcg tgctcgatgt gggccacgaa gtcacggtcc
    21841 atcttgagga cgtcgacggg cagccgggac agccgcgcca gggtggagtg gcccgtgccg
    21901 aagtcgtcga tggagatgac gcagccggcc tcgcggagag cggccagctc ccgctcgacg
    21961 cggtcctcgg cgtcgacgag caccgactcg gtgatctcca gcatcagccg ggaggccggc
    22021 acgcccgagg cggcgagcgc ccgcgccacg tcatcggcca ggcagcctgc ctgcaggtgc
    22081 cgcacggaga cgttcacccc cagcttcagg tcgtgcccct gcgccagcag cggcgccagg
    22141 gccgcggtcg cggcgccgag cacccagcgc tccagcggca cgatcagacc ctcgtcctcg
    22201 gccaccccga cgaactcctc cggggggacg tcgcccagtt cggcgtgccg ccagcggacg
    22261 agggcctcca ggccgagcac gcggccctcc tccacgccga cgaccggctg gagcgccacc
    22321 gacaggccgc cgtcggcgat cgcggcgggc aggtcccggg ccagccgggc gcgccggtcg
    22381 acgacccggt ccagggcctc tccggtggtc cggacgcagt tcttgccggc ggccttggcc
    22441 gcccgcagcg ccagatcggc ccgccgcacg gcctcggcgg ggtccccgcc gacggggagc
    22501 tcggcgacgc cgacgctgcc ggagacgggg agagccagcc cgccgcggcc actgccgtcg
    22561 ggcgccggcg gccggtggtc acggtcgagc agcacgacca gccgctcggc gagcacggtg
    22621 gcctcgtccc ggccggcgca caccaggacg gcgaactcgt caccgccgag ccgggcgacg
    22681 acgtcgtcct cccgcgcggc cgcgcgcagc gtctcggcca cctcgcagag cagccggtcg
    22741 ccctcgtcgt ggccggcgac gtcgttcacc gccttgaagc cgtcgaggtc gacgagcagc
    22801 aggcagccgg gggtggtgcc ggcggacacc tcgccgagcg ccgccatgaa gcgggcgcgg
    22861 ttgggcaggc cggtgaggaa gtcggtgtag gccatccgct ccagctcgcg ctgggtcgag
    22921 ctgcggtcgg tgacgtcgcg caggtgcagc accaggccgc cgctgtcgcc ggcgccggac
    22981 accccggcgg gggcggcgcc ggagggggcg gccccggtga gctcgacgtc acgccagcca
    23041 ccgccgcggg cgcgcagccg cgcggtcgtg ggcagcagtc ccaccgtggt gccgccgcgg
    23101 acggcctgcg cgacccgggg gacgaggtcg cggtctccct cgtcgagcag gtcggcgagc
    23161 agccgcccgg tgaggtcgcg gtcggtccag ccgagctggg cctccaccgc acccgaggcc
    23221 cagccgatgc ggccggtgcc gtccaggacg acggtgaccg cgtcgccgct gtgcaccaga
    23281 gcgcggaagt acccctcggt gcgcagcagg cgccgggtga gccggtagcc gtcgccggcc
//
