LOCUS       NZ_FNJX01000002        33462 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptococcus equinus strain pGA-7, whole genome shotgun sequence.
ACCESSION   NZ_FNJX01000002
VERSION     NZ_FNJX01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus equinus (Streptococcus bovis)
  ORGANISM  Streptococcus equinus
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900102715.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 14:53:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,759
            CDSs (total)                      :: 1,711
            Genes (coding)                    :: 1,703
            CDSs (with protein)               :: 1,703
            Genes (RNA)                       :: 48
            rRNAs                             :: 2, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 8
            CDSs (without protein)            :: 8
            Pseudo Genes (ambiguous residues) :: 0 of 8
            Pseudo Genes (frameshifted)       :: 1 of 8
            Pseudo Genes (incomplete)         :: 7 of 8
            Pseudo Genes (internal stop)      :: 0 of 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:06:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 59876
            Orig. end                         :: 93338
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNJX01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..33462
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..33462
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22790
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22790
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12790](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12790
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    15..31
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     misc_feature    340..355
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     misc_feature    504..518
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     gene            1269..2243
                     /db_xref="GeneID:63970418"
                     /gene="argF"
                     /locus_tag="BLR40_RS04980"
                     /old_locus_tag="SAMN04487837_1003"
     CDS             1269..2243
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970418"
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093840.1"
                     /locus_tag="BLR40_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1003"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_074533849.1"
                     /transl_table=11
                     /translation="MAYQDSFLKEIDFTKEELLNLIDLGLKFKSLKKEKIPHKYLEGLN
                     IALIFEKTSTRTRSAFTVAGQDLGMNVTYLGSSEIQLGKKESVIDTAKVLGSMFDGIEY
                     RGFKQEDVETLAEYSGVPVWNGLTDTWHPTQMIADFMTLKEVFEKLEGLTIAYVGDGRN
                     NMANSLLVTSAILGVNVKIIAPASLQPEAEIVELAKQHNTGAELTITDDLDAVKGVDML
                     YTDVWVSMGEKVDFKERIDLLLPYQINAELVEKTENPDVVVMHCLPAFHDLNTEIGKEI
                     FEKYGLSELEITDEIFQKYSSVIFREAENRMHSIKAIIYNSFK"
     gene            2366..2596
                     /db_xref="GeneID:63970419"
                     /locus_tag="BLR40_RS04985"
                     /old_locus_tag="SAMN04487837_1004"
     CDS             2366..2596
                     /codon_start=1
                     /db_xref="GeneID:63970419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /locus_tag="BLR40_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1004"
                     /product="DUF1797 family protein"
                     /protein_id="WP_004230761.1"
                     /transl_table=11
                     /translation="MESHLVRIINRLELMTTDGSNLKRNFERDGVVVAEVSFSNDPENG
                     PVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            2826..3512
                     /db_xref="GeneID:63970420"
                     /locus_tag="BLR40_RS04990"
                     /old_locus_tag="SAMN04487837_1005"
     CDS             2826..3512
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970420"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853706.1"
                     /locus_tag="BLR40_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1005"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_021141871.1"
                     /transl_table=11
                     /translation="MDFSFLPKYWAYFNYGVLVTIMISACVVFFGTIIGILVALVKRTN
                     IKILNWIASFYVWVFRGTPMVVQIMIAFAWMHFSNAPIVGFGVLDLDFSRLLPGIIIIS
                     LNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPVNAMRYVILPQALKNILPALGNEFIT
                     IIKDSSLLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMVTTVLSFLLKKLETRM
                     GNGGNN"
     gene            3512..4246
                     /db_xref="GeneID:63970421"
                     /locus_tag="BLR40_RS04995"
                     /old_locus_tag="SAMN04487837_1006"
     CDS             3512..4246
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970421"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805208.1"
                     /locus_tag="BLR40_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1006"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_004230766.1"
                     /transl_table=11
                     /translation="MSETLISIKGLHKYFGKNEVLKGIDLDIKAGEVVVIIGPSGSGKS
                     TFLRTMNLLETPTKGVITFEGVDITDKKNDIFKMREKMGMVFQQFNLFPNMTVLENITL
                     SPIKTKGVPKAEAEAKAYDLLDKVGLRDKANAYPTSLSGGQQQRIAIARGLAMDPDVLL
                     FDEPTSALDPEMVGEVLGVMQDLAKSGMTMAIVTHEMGFAREVADRVIFMDGGVIVEQG
                     SPKDVFENTKEARTKDFLSKVL"
     gene            4607..5083
                     /db_xref="GeneID:63970422"
                     /locus_tag="BLR40_RS05000"
                     /old_locus_tag="SAMN04487837_1007"
     CDS             4607..5083
                     /codon_start=1
                     /db_xref="GeneID:63970422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019802862.1"
                     /locus_tag="BLR40_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1007"
                     /product="ferrous iron transport protein A"
                     /protein_id="WP_021141873.1"
                     /transl_table=11
                     /translation="MILQNAKVGIPYTIVSVDLPDDSARHLSDLGLKVGASVKVVSKTP
                     TSAIVMLKSSRLAFDQSILSQIDVTEEEGALLSLPLSELKVGDYAYVDSIYAVNEAKRR
                     LMDMGLTRHTKIYLRKVAPLGDPIEISLRGYELTLRKSEAQMISVVKVDSEEEK"
     gene            5080..7218
                     /db_xref="GeneID:63970423"
                     /gene="feoB"
                     /locus_tag="BLR40_RS05005"
                     /old_locus_tag="SAMN04487837_1008"
     CDS             5080..7218
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970423"
                     /gene="feoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642824.1"
                     /locus_tag="BLR40_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1008"
                     /product="ferrous iron transport protein B"
                     /protein_id="WP_074533850.1"
                     /transl_table=11
                     /translation="MTEIALIGNPNSGKTSLFNLLTGTSQRVGNWPGVTVERKSGTVKK
                     HADWKVQDLPGIYSMSPYTPEEKVARDYLLSNDADSILNVVDATNLERNLYLTTQLIET
                     GIPVTVALNMSDALKAQGKTINVDKLSYQLGVPVVSTSAVKNTGVDKAIKKVANTTKAN
                     VDLIQYPTYSDQFEAAIKQIIDILGDVVPERSARFYAIKLFERDALVKEELDLSDFQKG
                     EINQVIKITEEIFTEDSESIVINERYAFIEKVAKMAQNQTSDFKMTASDKIDRIVTNRI
                     LALPIFAVAMFLVYYLSIQTVGTMGTDWVNDVLFGELVPGWVQSGLDALHVSGWLESLI
                     IDGIVAGVGTVLGFLPQIFVLFICLGILEDIGYMSRIAFVMDRVFRRFGLSGKSFIPML
                     IATGCGVPAVMASRTIENERDRRITIMTATFMPCSAKLAIIALIAGAFFPDNPFVAPST
                     YFIGVITIILSGIALKKTKLLGSYVSPFIMELPAYHMPKIASVLRYAFGKALSFVKRAG
                     TVIFSLTVIIWFMSTYNFAFQAVDTDNSILASLGKLISWIFAPLGFGNWKATVAAATGL
                     AAKEAVVGTFGILYNDSTTRGLYHALQLDYSALAGYSFLIFNLLCAPCFAAMGAIKREM
                     GDAKWTLGAIGFQTGLAYVVSLIIYQLGLVVLYGKGITFWTIVAVALLIAIIYFIVRKP
                     AQEPEKVITLDNLGEVGE"
     gene            7223..7369
                     /db_xref="GeneID:63970424"
                     /locus_tag="BLR40_RS05010"
                     /old_locus_tag="SAMN04487837_1009"
     CDS             7223..7369
                     /codon_start=1
                     /db_xref="GeneID:63970424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334428.1"
                     /locus_tag="BLR40_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1009"
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_024344240.1"
                     /transl_table=11
                     /translation="MATIIIALLIAVGVVMGLRSYIKGKGSCGDCNCSCPVKDNQRKSA
                     KTK"
     gene            complement(7406..8764)
                     /db_xref="GeneID:63970425"
                     /locus_tag="BLR40_RS05015"
                     /old_locus_tag="SAMN04487837_1010"
     CDS             complement(7406..8764)
                     /codon_start=1
                     /db_xref="GeneID:63970425"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069434.1"
                     /locus_tag="BLR40_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1010"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_024344241.1"
                     /transl_table=11
                     /translation="MNNNILKDTSLKYIFSFIFILGFNFFILSLTVFYVKNQQIVTPTI
                     NQLVDNISIQKNHISITQKGKNIIKNNDLWIMIINDTDGNEVFNINKPQNVQSHFTYSD
                     AIKFSKYYLNDYPIFSQEKNGKIILIAFPKNRIARYLTNYLDLNSVRTLPIIVIGTLLF
                     NCFYFFLLYRYSSNYISKNLSPLITAINKLPSGLNSKINSITELNTLTKAINKTDNLLK
                     QNSKFKEEWISGIAHDIKTPLSVIVSNTSLAIEKSAGNDISKHLNTILVESNYIQNLLN
                     DLNIFARLTNGDLKLNKEYVDIIPFFRQIIIQIINQEIWDNFDFEFEADDCLLGKKMYI
                     EKALISRVIHNLIYNSVLHNNKGCTVNIRLKNIDENKFLIIVKDNGIGASPDKLNNINE
                     IGKFDFDISGVRRSGMGLKISKQIIDLHQGTMDITSEQGKFFQTSITLPLNNK"
     gene            complement(8775..9476)
                     /db_xref="GeneID:63970426"
                     /locus_tag="BLR40_RS05020"
                     /old_locus_tag="SAMN04487837_1011"
     CDS             complement(8775..9476)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970426"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008623.1"
                     /locus_tag="BLR40_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1011"
                     /product="response regulator transcription factor"
                     /protein_id="WP_024344242.1"
                     /transl_table=11
                     /translation="MNFEESLLTKNILIVDDDYALNQSIKAVLLSKGFLNISSAYSIGE
                     AIDIFLSDKIELIILDVMLPDGEGFTLSKFIRNEKSEIPILFLTAKDNPNDEIAGFDAG
                     GDDYITKPFIPKNLIYRILALLRRTYKNELETISVGNCTLNIKNAIIEKNGTCIPVTPT
                     ELQILKKLIANKNYIVSIDSLCRTIWGPESYGYENSLIVHIRNIREKIEDNPSKPNHLL
                     TVRGLGYKFVL"
     gene            9665..9835
                     /db_xref="GeneID:63970427"
                     /locus_tag="BLR40_RS05025"
                     /old_locus_tag="SAMN04487837_1012"
     CDS             9665..9835
                     /codon_start=1
                     /db_xref="GeneID:63970427"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_d"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892259.1"
                     /locus_tag="BLR40_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1012"
                     /product="lacticin 481 family lantibiotic"
                     /protein_id="WP_074450945.1"
                     /sec_met_domain="L_biotic_A (E-value: 4.4e-29, bitscore:
                     94.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_d (E-value: 1.2e-05, bitscore:
                     20.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTNIIDIKATEALQELSLEELDTIIGAKKGSGVVPTVSHDCHM
                     NSWQFLFTCCS"
     CDS_motif       9665..9751
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNTNIIDIKATEALQELSLEELDTIIGA"
                     /locus_tag="BLR40_RS05025_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9752..9835
                     /prepeptide="core"
                     /locus_tag="BLR40_RS05025_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="5.40"
                     /molecular_weight="2891.3"
                     /monoisotopic_mass="2889.3"
                     /core_sequence="KKGSGVVPTVSHDCHMNSWQFLFTCCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNTNIIDIKATEALQELSLEELDTIIGA"
                     /leader_location="[9664:9751](+)"
                     /alternative_weights="2909.3"
                     /alternative_weights="2927.3"
                     /alternative_weights="2945.4"
     gene            10001..12790
                     /db_xref="GeneID:63970428"
                     /locus_tag="BLR40_RS05030"
                     /old_locus_tag="SAMN04487837_1013"
     CDS             10001..12790
                     /codon_start=1
                     /db_xref="GeneID:63970428"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BLR40_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1013"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_074533851.1"
                     /sec_met_domain="DUF4135 (E-value: 2.7e-72, bitscore:
                     238.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.5e-52, bitscore:
                     171.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKEVNLFNNYIDLIMKKYFTDVDNLFYDEVHSLILDLQMNLLIY
                     IINKKRLLGELKGDTPEERYKYFNEVLCSKGLILKEIEESYPEIIQRTQIQVNKYIKLY
                     KEVKDKFYRDFELLKKEKFILTDDYFVDDSKLSIKVSGDIHNGKGVCIVSYYNQKVVYK
                     NKKIESNRFIIDFLKIINDKLEDEMVLIPDFIGRDGYYWEKYIFHKQISNINDGKKFYT
                     NLGRLLCISYALNISDLHFENLIAFGKYPILVDVETIWNIGAFKTIAKDDSTKILIDKN
                     YDSILNTGLLPISSLNHSFGGDTSGILGGKFLGEIRDIVNLYRDDIHIERKQIKKENYN
                     HLPFIVKKCEVNYLEILDYIEDILNGFDEVGKILICDRGKIVKLVEKYKSKIEVRVLFR
                     NTREYGIIQALLLSPVYSKQEKLLFKKISQKLDYYSHEELSLSEEKQLLNMDIPYFSLK
                     ANQLTICENGRRVWSLQETPEQKVSIKINKISRELLEEQKKLIIFSIQVSKALYSPKLK
                     QLYSRFLDYSVNVEEINKGLEELVESILDKEVISEKDGTSNWLTLTVNDFDGLELEPMD
                     YSIYSGISGVSLAFLECYDILNDNLKKRVKETVLRIYHTIRNAYKQYSDNYSLYVGKLG
                     MLITLNKIESFFNLPTNLDFLDELRNICSNLCDSKNPDLLDGLSSVVDIIFSEDYLTDN
                     FREELVEIKEVLLNTVCFNEDGNAFWNKDSKPNVSLAHGNLGIEIALLELYILLGEPKI
                     KEIFMKAVNFDNSRKLNQGWLDIRNSSHSANWCHGSTGVLISRIKLLQMHDCHSCLSKN
                     EIIMFIDDIQHAIEDIQEVGIEMTNFSLCHGVCGNLLSLSYCIRNDIPINLKTFINSNF
                     LLDNFSKLNCFGQKNGWMCGYGTSYESLGLFTGISGIIFANAKFLKESMISKSSLLDI"
     cand_cluster    12593..33462
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    12593..33462
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[22592:23462](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22593..23462
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            12815..14893
                     /db_xref="GeneID:63970429"
                     /locus_tag="BLR40_RS05035"
                     /old_locus_tag="SAMN04487837_1014"
     CDS             12815..14893
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970429"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892264.1"
                     /locus_tag="BLR40_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1014"
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="WP_024344244.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-35, bitscore:
                     116.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIILQNNEEDCLLACYTMLLNDLGINIPLYEVYTKDSLPADGLN
                     LSYLLTLNNRFNVFIKGFHADFDNLYKIYKESRRRMILHWNQDHFVVAEKIMTDRVIIV
                     DPAIGRVQYSREEFLSHYSGTLVLVGKNDNFQRMKCKPIFWKYFKQTLNVKPIILFVIS
                     LLFVQLSVLLFSVTIRQMTSKDYAYCSSLFLLGSVIIFQILGFFIKNSALDKYNSDFDV
                     FYSKSLFQKLLEKPLLYFRNHLSGEISEKINFKSSLRDSVTLKIIPSCVSFISGIAIFF
                     YLMTISVNLTFILVGIISIYGIISATIYLKQIEYNQTYLQYLIDFNSEFQLDIDDIDYI
                     KIMRREEVVFNSWMTNNKKVTEKYSNIIKIESLSQLIGTIFNYLSLSSIIIISIYCKDY
                     VKISFSDLLVYQTSISLLISAIEQIKNAIFEVVRLGIYAEKQSDLLKDSKPIIVPNTNL
                     DEYLIKAENLNFTYDIQPIYKDINLTIHKGEKIAILGRSGSGKTTLLMLLAGVLRYSGS
                     LKYGVENFEKYLSIVLQNMTLRKGSILDNLEWSSDNLSPLYKVLEDTSADKIINNMPNK
                     IYSKILKQGKNLSGGQIQKILIAKSLLKKEAIIFWDEVFSNLDEESKKKIYKNVLQSSY
                     YSDETMLIVSHHLDIVDYVDYVIFIDDTTGEVIKDSHSNLLKTNRRYSEFINSKKLS"
     gene            14990..15898
                     /db_xref="GeneID:63970430"
                     /locus_tag="BLR40_RS05040"
                     /old_locus_tag="SAMN04487837_1015"
     CDS             14990..15898
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970430"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935046.1"
                     /locus_tag="BLR40_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1015"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_027967922.1"
                     /transl_table=11
                     /translation="MNNIIELKNLTKVYKDITTVNIERITVRRGEIYGFLGPNGAGKTT
                     TMKMILSLVSPSSGEILVNGKDIKKDYDYLSQIGSMIEEPSYYPNLTGYENLLVFQKMI
                     GFDKNNIWPTLKLVGLAEEKNRKKLVKAYSLGMKQRLALAFALVKKPSILLLDEPTNGL
                     DPAGIHEIRELILKLAKQEGLTVFISSHILSEIEHIADRVGIINHGQLVYEGEIEKIKS
                     NTWIKIGGDFSHKNIVQDLLKFGDLHIMGASTNHIKIGNIEDDILADVVTFLVENGYRI
                     FKVVREKESLEDIFLSLTREV"
     gene            15901..16665
                     /db_xref="GeneID:63970431"
                     /locus_tag="BLR40_RS05045"
                     /old_locus_tag="SAMN04487837_1016"
     CDS             15901..16665
                     /codon_start=1
                     /db_xref="GeneID:63970431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598724.1"
                     /locus_tag="BLR40_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1016"
                     /product="ABC transporter permease"
                     /protein_id="WP_039691058.1"
                     /transl_table=11
                     /translation="MVKVIQIELLKSKRTKSFMISFVIMLVAVVWSLLAASRSINSPKL
                     RTMGLFFNNLQAIPVFLPIATCLFVSRIVSNEKDGNTLKLQNSNNIKLMTVFNSKLFFS
                     NVVFFVLNIFQILIVYLDTVSHDIEAPLSNLALQLIGLTMSSFSLLTIFLYLAMILEKQ
                     GVLLGIGFLSGFLGIIMSETSKWLNLFFPFGGSSFLALYRIKVLQSGEHLDYVFVWDKT
                     VPLNFILYFIYCILIYFMVRYLLLKKQGENYA"
     gene            16658..17395
                     /db_xref="GeneID:63970432"
                     /locus_tag="BLR40_RS05050"
                     /old_locus_tag="SAMN04487837_1017"
     CDS             16658..17395
                     /codon_start=1
                     /db_xref="GeneID:63970432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990313.1"
                     /locus_tag="BLR40_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1017"
                     /product="ABC transporter permease"
                     /protein_id="WP_027967924.1"
                     /transl_table=11
                     /translation="MLSYFKAEWLKTRKIAILSVGLIFLALSSFIGLANFFINYNVLID
                     NQMSRVLWGQLTFYNAQLLFPAMLAIFSGMIIIPEFERKTLEMLRVNCISIPKLIINKL
                     VLSLILVAAIQGLLFLIYLVTLLISQTSFNISDLLLFFKATILSIVGSSSILMIHYYIV
                     SKTKNFAKSVGIAAIGSFIGFIFIMLGGVLNKFFPYSQPMIALRSRSLDSMSATELIIF
                     ILVNIFYTYIFYRLTVQTLVKKQ"
     gene            17552..18406
                     /db_xref="GeneID:63970433"
                     /locus_tag="BLR40_RS05055"
                     /old_locus_tag="SAMN04487837_1018"
     CDS             17552..18406
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961632.1"
                     /locus_tag="BLR40_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1018"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_027967925.1"
                     /transl_table=11
                     /translation="MATIIDGKALAVKKQTELVEKVEKLKAEMGVVPGLVVILVGDDPA
                     SQVYVRNKERSAKKAGFLSETVRLSESISEEELIQVIEQYNEDDRFHGILVQLPLPAHI
                     NDKRVILAIDPKKDVDGFHPINTGHLWNGRPVMVPCTPAGIMELLREYDIDLEGKTAVI
                     IGRSNIVGKPMAQLLLDKNATVTLAHSRTRHLARVTKQADVLIVAIGQGHFVTKEFVKE
                     GAVVIDVGMNRDENGKLIGDVKFDEVEPLASYITPVPGGVGPMTITMLLEQTYQSALRS
                     VKA"
     misc_feature    complement(17586..17595)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            18403..19236
                     /db_xref="GeneID:63970434"
                     /locus_tag="BLR40_RS05060"
                     /old_locus_tag="SAMN04487837_1019"
     CDS             18403..19236
                     /GO_function="GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531531.1"
                     /locus_tag="BLR40_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1019"
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="WP_027967926.1"
                     /transl_table=11
                     /translation="MIIDDKLARKVVTKRKADSHKGTYGRVLLIGGFYPYGGAIIMSAL
                     ATVKSGAGLVTVATERDNIPALHAHLPEAMAFDYEDEELLAENLAKADVVLIGPGLGEN
                     SKAKHVFDFVLSEAVEKQILIVDGSALNLLAKAMPISIKTCHLILTPHQKEWERLSGLA
                     IADQSLEKTQTALEKFSNGTILVAKSHHTKILQGSQVAELAVGGPYQATGGMGDTLCGM
                     IAGFVAQFKDNLFDTVAVATYLHSAIAEKLSQEAYVVLPTTISAELPKVMKQLSE"
     misc_feature    complement(19282..19291)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    complement(19403..19418)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            19469..20089
                     /db_xref="GeneID:63970435"
                     /locus_tag="BLR40_RS05065"
                     /old_locus_tag="SAMN04487837_1020"
     CDS             19469..20089
                     /codon_start=1
                     /db_xref="GeneID:63970435"
                     /inference="COORDINATES: protein motif:HMM:NF039400.4"
                     /locus_tag="BLR40_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1020"
                     /product="DUF6287 domain-containing protein"
                     /protein_id="WP_074533852.1"
                     /transl_table=11
                     /translation="MKKGCKTTVILLSSLFLLGACSKNEKGTSASSSHAKVIQTSNSTA
                     AKKVVKSSASSYQESVVSSSSVTEIEPTVGVAEVVETTQTLPSQSQSSSNEDRLDLEQI
                     AYGDFSSLSGTWTNDLGESITLTQDGQVSLSQSQALYQITTNIVKDDVYFGTIYNPGSM
                     TDSAAFIVVPNGVADPFLGEVGTNDRLIVGQCGSASEHPFFKH"
     gene            20301..20870
                     /db_xref="GeneID:63970436"
                     /locus_tag="BLR40_RS05070"
                     /old_locus_tag="SAMN04487837_1021"
     CDS             20301..20870
                     /EC_number="2.-.-.-"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531529.1"
                     /locus_tag="BLR40_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1021"
                     /product="L,D-transpeptidase"
                     /protein_id="WP_074533853.1"
                     /transl_table=11
                     /translation="MRKKFSKKVLILLLTFANLVVGYSLCRQLMVIRQESDVKIDVYAF
                     DKNVKKSQKKIYPDLSELDHLSILVSISQQKMIVYSGNKVIFKTKVSTGAKETPTPTGK
                     FAIEAERGEFLYDDSLNRGACDWVSFKDHGGYRFESLPTDWKGKILKGESKKIGTACTD
                     GNVRLLKEDAKWLFENMPEGVIVSIH"
     misc_feature    complement(20913..20928)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.6"
                     /tool="antismash"
     misc_feature    complement(20962..20977)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.6"
                     /tool="antismash"
     gene            21060..22388
                     /db_xref="GeneID:63970437"
                     /gene="xseA"
                     /locus_tag="BLR40_RS05075"
                     /old_locus_tag="SAMN04487837_1022"
     CDS             21060..22388
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970437"
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961637.1"
                     /locus_tag="BLR40_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1022"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_074533854.1"
                     /transl_table=11
                     /translation="MSDYLSVSTLTKYLKLKFDRDPYLERVYLTGQVSNFRRRPTHQYF
                     SLKDENAVIQATMWAGTFKKLGFELEEGMKINVVGRVQLYEPSGSYSIIIEKAEPDGIG
                     ALAVQFEQLKKKLAEAGYFDDRHKRQLPQFVKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     EILLFPTKVQGEGASQEVADNIAKANERDDLDLLIVGRGGGSIEDLWAFNEEIVVQAIF
                     ESRLPVISSVGHETDTTLADYVADRRAATPTAAAELATPVTKADIISWIAERENRMYQA
                     SLRRIKQNQERLDKLANSVIFRQPERLYDGYVQKLDRLTMSLTNTMQNQFSQAKQSHAL
                     LHQRLLALDFESQIKHYQDKLQSLERLLLSNMTSQYDSNLARFEKAQDALLSLDTSRII
                     ARGYAVVQKNEKVISSVSDVKVGDQLTIQLKDGQLEAEVKDAK"
     gene            22378..22593
                     /db_xref="GeneID:63970438"
                     /locus_tag="BLR40_RS05080"
                     /old_locus_tag="SAMN04487837_1023"
     CDS             22378..22593
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /db_xref="GeneID:63970438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014634320.1"
                     /locus_tag="BLR40_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1023"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_021141880.1"
                     /transl_table=11
                     /translation="MPSKKTFEENLQDLEAIVTKLENGDVALEDAISEFQKGMVLSKEL
                     QKTLDQAEKTLVKVMQDDGVETELDA"
     gene            22593..23462
                     /db_xref="GeneID:63970439"
                     /locus_tag="BLR40_RS05085"
                     /old_locus_tag="SAMN04487837_1024"
     CDS             22593..23462
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970439"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063739.1"
                     /locus_tag="BLR40_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1024"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_074533855.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-52, bitscore:
                     172.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKVKKIGQAIHRYYKQKDIVSPDLIEAILYSVDAGGKRVRPLIF
                     LELLEGFGVVLTDAHYDVAAAIEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKKFNEATA
                     ILAGDSLFLDPYDLVANAELSAEVKVALIAELAHASGTYGMVGGQMLDMEGEERKLSLS
                     ELQLIHANKTGKLLTFPVVAAGIVAGLAGEDINNLRKAGSLIGLAFQVRDDILDVTASF
                     EEIGKTPKKDLLADKATYPSLLGLDKSYDILNESLDEALAIFQKLSETQGLQTEKIAEL
                     IERLRLNA"
     gene            23455..24279
                     /db_xref="GeneID:63970440"
                     /locus_tag="BLR40_RS05090"
                     /old_locus_tag="SAMN04487837_1025"
     CDS             23455..24279
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642835.1"
                     /locus_tag="BLR40_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1025"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_021141883.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVNVINGERYDKPGE
                     KIDDGTELKLKGEKLKYVSRGGLKLEKALQVFEISVDGQTTIDIGASTGGFTDVMLQNG
                     AKLVYAVDVGTNQLVWKLRQDERVRSMEQYNFRYAELADFTEGQPTFASIDVSFISLNL
                     ILPALHNILAENGQVVALIKPQFEAGRDQIGKNGIIRDKAVHQKVLETVTSFAVDYGFT
                     VKGLDFSPIQGGHGNIEFLAHLEKSANAQNLVATLIPEIVEKAHKEFKDEKE"
     gene            24266..24736
                     /db_xref="GeneID:63970441"
                     /locus_tag="BLR40_RS05095"
                     /old_locus_tag="SAMN04487837_1026"
     CDS             24266..24736
                     /codon_start=1
                     /db_xref="GeneID:63970441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004230804.1"
                     /locus_tag="BLR40_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1026"
                     /product="arginine repressor"
                     /protein_id="WP_021141884.1"
                     /transl_table=11
                     /translation="MKKSERLELIKKIVAENAVETQHDLLKLLEAEGLTLTQATISRDM
                     NEIGIIKVPSVDGPYIYGLSKDKTKKVGQVSVPIKSTVLAISEETAGLENMINLDVIPG
                     NSRLIKRYLLEDFKDSLFSVIADDDSLLVVAKTAEAANAIRQEVRKWMTDHK"
     gene            24749..26407
                     /db_xref="GeneID:63970442"
                     /gene="recN"
                     /locus_tag="BLR40_RS05100"
                     /old_locus_tag="SAMN04487837_1027"
     CDS             24749..26407
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970442"
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014619981.1"
                     /locus_tag="BLR40_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1027"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_074533856.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEEISLTFENGMTVLTGETGAGKSIIIDAMNLM
                     LGARASLDVIRHGAKKAEIEGLFSVGENAALTHILEENGIDISDELIIRREILQNGRSI
                     SRINGQMVNLTTLRAVGQYLVDIHGQHDQEELMKPNMHIRMLDEFGDEHFSAVKKHYRE
                     IFESYRTLRKRVLTKQKNEQEHKARIEMLEFQIAEIEAAALKSGEDQALNQKRDKLLNH
                     KHIADTLTNAYVMLDDEEFSSLSNIRSAMNDLMSLEEFDQDYKEMSANVSEAYYILEEV
                     TKHLGDVIEDLDFDAGSLQQIEARLEVIYSITRKYGGSVDDVLDYYENITKEYNLLTGS
                     DESSDDMEKELKHLEKELILAADELAQERHKLAKDLEAEIKQELADLYMEKADFQVQFT
                     KGKFNRDGNEVVEFYISTNPGEGFKPLVKVASGGEISRLMLAIKSAFSRKEDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGSHGQVLAISHLPQVIAIADYQFFIEKRSDENTTVSTV
                     RLLTEEERVEEIAKMLAGSDITEMAREQARELLKK"
     gene            26532..27374
                     /db_xref="GeneID:63970443"
                     /locus_tag="BLR40_RS05105"
                     /old_locus_tag="SAMN04487837_1028"
     CDS             26532..27374
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="BLR40_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1028"
                     /product="DegV family protein"
                     /protein_id="WP_004230806.1"
                     /transl_table=11
                     /translation="MSKIKIVTDSSLTIEPELVEKYDITVVPLSVMIDGVVYSDNDMKE
                     EGKFLNLMRNSKELPKTSQPPVGVFAEVYENLMKDGAEHIVSIHITHTLSGTVEAARQG
                     ANLAGADVTVIDSTFTDQCQKFQVVQAAKLAQEGASLEEVIAKVEEVRQKSELFIGVST
                     LENLVKGGRIGRVTGLLSSLLNIRVVMEMIDCELNTVIKGRGVKTFNKWLDSFIEHAQA
                     SGKKVAEIGISYCGTADMANGFKEKLEVLGAPIAVLETGSIIQTHTGEDAFAVMVRYE"
     gene            27367..28215
                     /db_xref="GeneID:63970444"
                     /locus_tag="BLR40_RS05110"
                     /old_locus_tag="SAMN04487837_1029"
     CDS             27367..28215
                     /codon_start=1
                     /db_xref="GeneID:63970444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642837.1"
                     /locus_tag="BLR40_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1029"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_074533857.1"
                     /transl_table=11
                     /translation="MSNKKNFLIGFAFFLASLLLFIVVFNLLIPKSDQELTKKDFLAQE
                     AKHFNYVAVGDSLTEGVGDTTNQGGFVPLLSQAMTDTYNYQVTYSNYGISGNTSQQILS
                     RMKKQEAIQKSLAKADMMTLTVGGNDVMAVIRKHLTQLSVSTFKKPATAYQKRLRQIIE
                     LARSENEDLPIYVLGIYNPFYLNFPEMTEMQEIIDNWNESTESVTDEYDNVYFVPINDQ
                     LYKGIDGEEGIVSTSGDQTTVINDALFSGDHFHPNNIGYQIMSDVTMEKINETKQEWNK
                     D"
     gene            28184..28786
                     /db_xref="GeneID:63970445"
                     /locus_tag="BLR40_RS05115"
                     /old_locus_tag="SAMN04487837_1030"
     CDS             28184..28786
                     /codon_start=1
                     /db_xref="GeneID:63970445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004230808.1"
                     /locus_tag="BLR40_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1030"
                     /product="YpmS family protein"
                     /protein_id="WP_004230808.1"
                     /transl_table=11
                     /translation="MKLNKNGTKTNWWKWGFLLILAINVAFVGVIASRLIQVREPAAQS
                     ISSKKADNVKVGTISTTREQLNDTVASYLKEYQTKKTSYSVYATSSAIMFEGTYTFLGY
                     EVPLYIYFQPSRLESGAIQLKITSFSVGTLTLPESEVLKYLKSSINLPDFVEVLPKESV
                     ININIQDIKNDADIFLKATTIDLVGDQFNFDIYKKNS"
     gene            28881..29156
                     /db_xref="GeneID:63970446"
                     /locus_tag="BLR40_RS05120"
                     /old_locus_tag="SAMN04487837_1031"
     CDS             28881..29156
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970446"
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="BLR40_RS05120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1031"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_009853724.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIESFLSEGEKVQL
                     IGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            29306..29506
                     /db_xref="GeneID:63970447"
                     /locus_tag="BLR40_RS05125"
                     /old_locus_tag="SAMN04487837_1032"
     CDS             29306..29506
                     /codon_start=1
                     /db_xref="GeneID:63970447"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531519.1"
                     /locus_tag="BLR40_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1032"
                     /product="hypothetical protein"
                     /protein_id="WP_021141889.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKSLLLVVIFLGAFSLFKAAMLIMVGMAMKPKVDEDGNIVKPVE
                     EEDEEKQPSINEDDSDFWDNW"
     misc_feature    complement(29690..29708)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 23.99"
                     /tool="antismash"
     misc_feature    complement(29791..29805)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.49"
                     /tool="antismash"
     gene            29847..31337
                     /db_xref="GeneID:63970448"
                     /locus_tag="BLR40_RS05130"
                     /old_locus_tag="SAMN04487837_1033"
     CDS             29847..31337
                     /codon_start=1
                     /db_xref="GeneID:63970448"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751098.1"
                     /locus_tag="BLR40_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1033"
                     /product="peptide MFS transporter"
                     /protein_id="WP_024344257.1"
                     /transl_table=11
                     /translation="MENNKIEQTFFGQPKALFTLFQTELWERFSYYGMRAILIYYLYAS
                     VTAPNAGLGLPKPQAMAIVSIYGALVYLSGIIGGWFADRVLGASQTIFIGGILITLGHI
                     VLAVPFGLTSLFISLFFIILGTGMLKPNISNMVGHLYAADDPRRDTGFNIFVIGINIGS
                     LLAPIVVGTVGQSINYHLGFSLAAIGMVLALFVYWFGRMKQFPELGNKPSNPMTSAEKR
                     GLLVKLAIGLVICAVGGTFLYRANPSNFVNNLVNILSMAGIFIPFIYFVMMFASKKVSS
                     TERKQLLAYLPLFLSSIIFWLVEEQSATVIAVWGETRSNLHPTIFGMNLYIDPSWYQLL
                     NPLFIVALTPAFVWLWNKMGERQPSPVTKFGLGLLLTGVSYLIMALPGILYGTDKRVSF
                     MWLVIMFAVQMAGELLVSPVGLSVSTRLAPLAFQSQMVALWFLADSTSQAVNALITPYF
                     TKETEVAFFGILGLVCLAVGVMLLFINKPVLKLMRNDK"
     gene            complement(31486..32421)
                     /db_xref="GeneID:63970449"
                     /locus_tag="BLR40_RS05135"
                     /old_locus_tag="SAMN04487837_1034"
     CDS             complement(31486..32421)
                     /EC_number="1.3.98.1"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /locus_tag="BLR40_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1034"
                     /product="dihydroorotate oxidase"
                     /protein_id="WP_074533858.1"
                     /transl_table=11
                     /translation="MVSTATKIGSFDFDNCLMNAAGVYCMTREELAEIEDSAAGSFVTK
                     TGTLVARPGNPEPRYADTALGSINSMGLPNHGYQYYLDYVTELQNNPESKNHFLSLVGM
                     SEEETHTILKAVQASDYQGLVELNLSCPNVPGKPQIAYDFETTERILTDIFTYFTKPLG
                     VKLPPYFDIAHFDRAAAIFNKFPLTFVNCINSVGNGLVIDDETVVIKPKNGFGGIGGDY
                     VKPTALANVHAFYKRLNPSIQIIGTGGVKSGRDAFEHILCGASMVQLGTILHQEGPAAF
                     ARITDELKAIMEEKGYETLDDFRGKLHYID"
     gene            32737..33051
                     /db_xref="GeneID:63970450"
                     /locus_tag="BLR40_RS05140"
                     /old_locus_tag="SAMN04487837_1035"
     CDS             32737..33051
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:63970450"
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531516.1"
                     /locus_tag="BLR40_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04487837_1035"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_074533859.1"
                     /transl_table=11
                     /translation="MKDNNKSQNLLQGDLLNNVSSFFKALGNTTRLQIICCLSKGELKS
                     SELAETLGMTPSAVSHQLSLLKNLKIVSVRRDGKNQIYALADRHISQVLESVVEHYQED
                     "
ORIGIN
        1 tcaactttta caggttgcat acgacgttca agtgctgcat ctttttcgat aatacggtat
       61 tcgttaagag tagtagcacc aactaattgt aattcaccac gtgcaagagc tggttttaaa
      121 atgttaccag catccatgtt accatcgcca gcattaccag caccaacaat ttcatggatt
      181 tcatcgataa acaaaattac gtctttgcgt tcacggattt cttccatgag tttttgcatg
      241 cgttcttcaa attgtccacg gataccagtt ccttgaacaa ggcttacgac atcgagacga
      301 atgacttgtt tgttttggag tttttgagga acattaccat caacgatttt ttgagcgagc
      361 ccttcaacaa cagctgtttt accaacacca ggttcaccaa tcaaaacagg gttgtttttt
      421 gtacggcggt taagaatttc gataactcga atgatttcag aatcacgtcc cacaacaggg
      481 tcgatatcac cacgtcgtgc aatatcagtg acgttgatac caaattcttc taacaagcct
      541 tttggctctt gttgttgagc ttgagcgcct tgacggaagt tgccatttcc gttgccgcca
      601 cgtccattat ttcctccacc aggttgtgtt ggaggggtat tttgaaatcc ttggccacca
      661 aatgcaggga agccaccgag attgctaaag aaatcatcga aaggatttgt tgattgatta
      721 gttgcgttag aggttggttg agaatttcca cccaaacctc ctaagatagc gttatttggg
      781 tcagttttca tgatttgata gcagttttgg cacaaatcaa tttgtctttg ctgaccatta
      841 acatttgtat acaggtgaat tgttgattcg tttaaatgac aattctgaca gagcatataa
      901 aataccctcc tttcgtaatg gtctgactaa tgtcctaaag gtcaaagata gtcagatttc
      961 atacttacat tatagcacta gcgattagga aatcaagtaa aaagcatcaa aaattagcac
     1021 tcttacaaaa agagtgctaa tccttaagga ctaattgaga aagccctaat gtggtacgat
     1081 attctttgac ttggttcatt ttttctcctt attaataatc actagcatag taaattatat
     1141 gtgatatatc aattataaat gacataaaga tgaataatta ttttattttt attcagaaat
     1201 cacttgacaa gatgtataat tatgctagaa ttaggtatat tattcaaaaa gaaaaggtgg
     1261 aaagaagtat ggcatatcaa gattcatttt tgaaagagat tgattttact aaggaagagc
     1321 tgcttaatct tattgattta ggattgaaat ttaaatcatt gaaaaaagaa aaaattcctc
     1381 ataaatattt agaaggattg aatattgcac taatttttga aaaaacaagt acacgaacac
     1441 gttctgcgtt tacagtggct ggacaagacc tcggaatgaa tgtgacttac cttggcagca
     1501 gtgaaattca acttggtaaa aaagaatctg tcattgatac cgcaaaggtg cttggttcga
     1561 tgtttgatgg tattgagtac cgtggcttta agcaagaaga cgttgaaact ttggcagaat
     1621 attcaggagt gccagtctgg aatggcttga ctgatacttg gcatccaact cagatgattg
     1681 ctgattttat gacattaaaa gaagtatttg aaaagctaga aggtcttacg attgcttatg
     1741 ttggtgatgg tcgtaataat atggcgaatt ccttgcttgt tacttcagct atcttaggtg
     1801 tcaatgtcaa aattatcgct ccagctagtt tgcagcctga agctgagatt gttgagcttg
     1861 caaaacagca caataccggc gcagaattga cgattacaga tgatcttgat gctgtcaaag
     1921 gtgtagatat gctttatact gacgtttggg tttcaatggg agaaaaagtt gattttaaag
     1981 aacgtatcga ccttttactt ccttatcaaa ttaatgctga gttggtagaa aaaacagaaa
     2041 atcctgatgt ggttgttatg cattgcctgc cagcttttca tgatttaaat actgaaatcg
     2101 gaaaagaaat ttttgaaaaa tatggtttgt ctgagttaga aattactgat gaaatctttc
     2161 aaaaatacag ttcagtcatc tttagagagg ctgaaaatcg tatgcattca atcaaagcaa
     2221 tcatctataa ttcctttaaa tagacgcaaa gcgttagatt ttgacaagaa attgttataa
     2281 atgtgagaaa atgcactcct ttgttgtttg tttagtagaa tttatgttaa aatagataag
     2341 acaataaacg aagaggagaa tagtcatgga atcacatttg gtgagaatta tcaatcgtct
     2401 tgaattgatg acgactgatg gtagcaatct taaacgtaat tttgaacgtg atggtgtcgt
     2461 tgtggcagaa gtgtctttca gcaatgaccc tgaaaatggt ccagttttca ctttgcgtga
     2521 tgttgaagct cgtgagtcat actcatttga tagcatcgac ttgatcgcaa tggaaattta
     2581 cgatcttctt tactaagata aagaaaaatt caggacagag tataagggca aagggtgtat
     2641 tttttcgccc tttccatcct atttagtgtg gtttctatgc tttcttatat tactattttg
     2701 aattgataag ggtccgcaga tgcgggcttt ttatttttaa taaagctatt taatacttat
     2761 gaattattgg tatttttatt caatgtgtgc tataattaat tgattattgc atataggaga
     2821 cataaatgga tttttcattt ttaccaaagt attgggctta ttttaactat ggtgtccttg
     2881 ttactatcat gatttcagca tgtgttgtct tttttgggac aatcattggt atcttggttg
     2941 ctttagttaa gcgtacgaat attaaaattt taaattggat tgctagtttt tatgtttggg
     3001 tttttcgtgg aactccgatg gtcgttcaga ttatgattgc ctttgcttgg atgcacttta
     3061 gcaatgctcc aatcgtagga tttggtgtct tggaccttga tttttcacgt ttgcttccag
     3121 gtatcattat tatttcacta aatagcggag cttatatttc tgaaattgtc agagcaggta
     3181 ttgaagcagt gccaaaaggt caacttgaag cagcttattc attaggaatt cgtcctgtga
     3241 atgctatgcg ttacgtcatt ttgccacaag cacttaaaaa tattttgcca gcccttggga
     3301 atgaatttat tacaattatc aaagatagct cacttcttca aacaattggt gttatggaat
     3361 tgtggaatgg tgctcaatca gttgtaacag caacttacct accaatcaca ccattgctat
     3421 ttgcagcttt ctattactta atggttacta cagttttgtc atttttactt aaaaaacttg
     3481 aaactcgtat gggaaatgga ggcaataact aatgtcagaa acactaattt caattaaagg
     3541 ccttcataag tatttcggga aaaatgaagt tctaaaaggt attgatcttg atattaaagc
     3601 aggagaagtg gttgttatta ttggaccttc tggttcagga aaatcaacat tccttcgtac
     3661 aatgaacttg cttgaaacac caacaaaagg tgtgattact tttgaaggag tcgatattac
     3721 tgataagaaa aatgatattt tcaaaatgcg tgaaaaaatg ggaatggttt tccaacaatt
     3781 taaccttttc cctaatatga cagtccttga aaatattact ctatcaccga ttaagactaa
     3841 aggtgttcca aaagcagagg cagaagctaa ggcttatgat ttgcttgata aagttggtct
     3901 tcgtgataaa gccaatgcct atccaacaag tctttctggt ggtcaacaac aacgtattgc
     3961 tattgcacgt ggacttgcta tggatccaga tgttcttctc tttgatgaac caacatcagc
     4021 tcttgaccca gaaatggttg gagaagttct tggtgttatg caagatttgg caaaatcagg
     4081 tatgacaatg gctattgtaa ctcacgaaat gggatttgcg cgcgaagtcg ctgaccgtgt
     4141 tattttcatg gacggtggtg tcattgttga gcaaggttca ccaaaagacg tttttgaaaa
     4201 tactaaagaa gctcgtacaa aagatttctt gagtaaggta ttgtaatatt aaaaaactca
     4261 gttggttttg aattcaactg agatttttta tatatagtag aaaagttaaa tacggttaaa
     4321 aataataatt acattaataa aaaatgagta cattttatac attaagcaca cttaattatt
     4381 ataatttagt catcttttta agggtgctta aaaagaaaac gatagtgaaa acagctagat
     4441 tataacgatt ctaaaattaa gtgtgcttta tttagaatga ttacaattaa tgcataaata
     4501 gagaaaaaaa ttaattttta taggtttatc tgcttatttt tatgatataa tgaatcggac
     4561 ggaaggtcaa atattttacc aaaaaaattt gaggaggtca agaaatttga ttttgcagaa
     4621 tgctaaagtt ggtattcctt atactattgt cagtgttgac ttgcccgatg atagtgctag
     4681 acacttgtct gatttggggt taaaagtcgg tgcttcagtt aaagttgttt cgaaaacacc
     4741 aactagcgcg attgttatgc ttaaatcaag tcgtttggct tttgatcaat cgattttaag
     4801 ccagattgat gtcacagaag aagaaggtgc tcttttatca cttcctcttt cagaattaaa
     4861 agtaggagac tacgcttatg ttgatagtat ttatgctgtc aatgaagcaa aacgccgtct
     4921 catggatatg ggattaacgc gtcacacaaa aatttaccta cgaaaagttg ctccgttagg
     4981 agacccaatt gaaattagct tacgcggtta cgaattgaca cttcgtaagt ctgaagcgca
     5041 aatgattagt gtcgtaaaag tagatagcga ggaggaaaaa tgacagagat agccttaatc
     5101 ggtaatccga atagtggtaa aacaagtctt tttaacttat tgactggtac aagtcaacgt
     5161 gttggtaact ggccaggtgt tacggttgaa cgtaaaagtg gtacggtaaa aaaacatgct
     5221 gactggaaag ttcaggattt accaggtatt tattcaatgt caccttatac gcctgaagaa
     5281 aaagttgcgc gtgattattt attgagtaat gacgccgaca gcattcttaa tgttgttgat
     5341 gcgacaaact tggaacgtaa cctttacttg acaactcaat tgattgaaac tggtattcca
     5401 gtaactgttg cgcttaatat gagtgatgcg cttaaagctc aaggaaaaac aatcaatgtt
     5461 gataaattgt cttatcaatt aggtgttcca gttgtttcaa caagtgctgt taaaaatact
     5521 ggtgttgata aagctatcaa aaaggttgct aacacaacaa aagctaatgt tgatttgatt
     5581 caatacccaa catatagcga tcaatttgaa gcagcgatta aacaaatcat tgacatcttg
     5641 ggtgatgttg tcccagaacg ttctgcacgt ttttatgcta ttaaactctt tgaacgagat
     5701 gcccttgtta aagaagaact tgatttgtct gatttccaaa aaggtgaaat caatcaagtc
     5761 attaaaatca cagaagaaat cttcacagaa gattcagagt caattgtgat taatgaacgt
     5821 tatgccttca ttgaaaaagt tgctaaaatg gctcaaaatc aaactagcga cttcaagatg
     5881 acagcttctg ataagattga ccgaattgtt acaaaccgta tcttggcttt gccaattttt
     5941 gcagtagcta tgttcttggt ttactatctt tcaattcaaa ctgttggtac aatggggact
     6001 gactgggtta atgatgtgct ctttggtgaa ttggtgcctg gttgggttca atctggactt
     6061 gatgctcttc atgtttctgg ttggcttgaa tctcttatca ttgatggtat cgtggctggt
     6121 gttggtacag ttcttggatt tttgccacaa atctttgttc tattcatctg tttaggaatt
     6181 ttggaagata ttggttacat gagtcgtatc gcttttgtca tggaccgtgt cttcagacgt
     6241 tttggtttgt caggtaaatc attcattcca atgttgattg ctactggatg tggtgtgcca
     6301 gcggttatgg caagtcgtac cattgaaaat gaacgtgacc gtcgtatcac aatcatgaca
     6361 gcgacattta tgccatgttc tgctaaatta gctattatcg ccttgattgc aggtgctttc
     6421 ttcccagata atccatttgt tgcgccatca acatacttca tcggcgttat tactattatt
     6481 ctttcaggta ttgctcttaa gaaaacaaaa ttacttggaa gttatgttag tccgtttatc
     6541 atggaattac cagcttatca catgccaaaa atcgcaagtg ttcttcgcta cgcttttggt
     6601 aaagccctta gctttgtgaa acgtgctggt acagttatct ttagcttgac agttattatt
     6661 tggttcatgt caacttacaa ttttgctttc caagcagttg atacagacaa ttcaatcttg
     6721 gcttcacttg gtaaattgat ttcttggatt tttgcaccac ttggatttgg taactggaag
     6781 gcgactgtgg ctgctgcaac aggtcttgct gccaaagaag ctgttgtcgg aacatttggt
     6841 atcttgtaca acgacagtac aacacgtggc ttgtatcacg cattgcaact tgattattca
     6901 gctcttgcag gatattcatt cttaatcttt aaccttcttt gtgcaccatg ttttgcagct
     6961 atgggagcta ttaaacgtga aatgggtgac gctaagtgga cacttggtgc tatcggattc
     7021 caaacaggtc ttgcttacgt cgttagtctg attatttatc aattaggtct tgttgtttta
     7081 tacggtaaag gtatcacttt ctggacaatc gttgcagtag cgctattgat tgcaattatt
     7141 tactttatcg ttagaaaacc agctcaagaa cctgaaaaag tgattacttt agataatcta
     7201 ggagaagttg gagaataagc ctatggctac aattataatt gcattgttga ttgcagttgg
     7261 tgttgttatg ggattgcgca gttatatcaa gggcaaaggc tcttgtggcg actgcaattg
     7321 ctcatgccca gtcaaagaca atcaacgtaa aagtgcaaaa acaaaataaa aaaatttcct
     7381 ctactcattg agtagaggaa attttttact tattattcaa tggtaatgtg attgaagttt
     7441 ggaaaaattt tccctgttca cttgtaatat ccattgtccc ctggtgtaaa tcgataattt
     7501 gtttagaaat ttttagtccc atcccgcttc ttcgaacacc ggaaatatca aaatcaaatt
     7561 ttcctatttc attaatatta tttaatttat caggagaagc tccaatacca ttgtctttta
     7621 caatgattaa aaatttattt tcatcaatat tttttaatct gatattgacc gtacagcctt
     7681 tgttattgtg aagtacagag ttataaatta aattatgaat tacacgagaa attagtgctt
     7741 tttctatata catcttttta cctaataaac aatcatcagc ttcaaattca aagtcgaaat
     7801 tatcccaaat ttcttggtta ataatttgaa tgataatttg tctgaaaaat ggaatgatat
     7861 ctacatattc tttgttaagt tttaaatctc cattagtaag tctggcaaat atgtttaaat
     7921 catttaataa gttttgaata taattactct caaccagtat tgtattaaga tgttttgaga
     7981 tgtcattgcc cgctgatttt tcgatagcta gtgatgtatt agaaacaata acagataatg
     8041 gtgtttttat gtcatgagct atacctgata tccattcttc tttaaatttt gaattttgtt
     8101 ttaaaagatt atcagtttta ttaatagctt tagttagagt gtttaattca gttattgaat
     8161 taattttact gtttaagcca ctagggagtt tgttgatagc tgtaatcaac ggagacagat
     8221 ttttagagat ataattacta ctataacgat aaagtaagaa aaagtagaag cagttgaaaa
     8281 gtagggttcc tattacgatg attggtaatg ttctgacgct atttaaatcg agataattag
     8341 taagatatcg agcaattcga tttttaggga aggcaattag tattattttc ccattttttt
     8401 cttgagaaaa aatggggtag tcatttagat aatattttga aaatttaata gcgtcagaat
     8461 aggtgaagtg tgattgaaca ttttgaggtt tgttaatatt aaaaacttca tttccgtcag
     8521 tatcattaat tatcataatc cataaatcat tattttttat gatatttttt cctttttggg
     8581 tgatgctaat atgatttttt tgaattgaaa tattatctac gagctgattt attgtaggag
     8641 taacaatttg ttgattttta acataaaaga ctgttagtga aagtataaaa aagttaaaac
     8701 ctagaataaa aataaaagaa aaaatatatt tcaaactagt atcttttaga atattgttat
     8761 tcatgacgtt ccctctataa aacgaattta taacctagtc ctctaacggt taataagtgg
     8821 ttgggcttag aggggttatc ttcaattttt tcacgaatat ttcgaatgtg aacaattagt
     8881 gaattttcgt aaccgtagct ttcgggtccc caaattgttc tacataggga gtctattgag
     8941 acaatgtaat tcttgttggc aattaatttt tttaggattt gtaattctgt aggggttact
     9001 ggaatacaag taccattttt ttcaatgatg gcatttttta tatttaatgt acagtttcct
     9061 acagaaatgg tctcaagttc atttttataa gttcttctaa gtagagcaag gattctatat
     9121 ataagattct tggggatgaa gggtttagta atgtagtcat ctcccccagc atcaaaacct
     9181 gcaatttcat cgttaggatt atcctttgcg gttaaaaata aaatgggaat ttcagatttt
     9241 tcattgcgaa taaatttaga aagagtaaag ccttctccgt cgggtaacat tacatctagt
     9301 ataataagtt caattttatc tgataaaaaa atatcaatag cttcaccaat agagtatgca
     9361 cttgagatgt ttaaaaatcc cttgcttagt aaaactgcct ttattgattg gtttaatgcg
     9421 taatcatcat cgacaattaa aatatttttc gttaataaac tttcctcgaa attcatcata
     9481 aatcctctaa ttattaataa tatgtgcctt aattatatca tatcagaatt acttgtataa
     9541 ttaagataat ctcttcttaa tgtaaatttt agctaatctt tatgtgcgaa ttttagactt
     9601 atttatgtaa cgaaggtaaa gtgattgctg tgcaatgtta tattaaattt aagaggagat
     9661 tttgatgaaa aatacaaata ttattgatat taaggcaact gaagctttac aagaattaag
     9721 tttagaagaa cttgatacaa ttattggagc taaaaaaggg agtggcgtag taccaacagt
     9781 ttctcatgat tgccatatga attcatggca atttttgttt acctgctgtt cataattaaa
     9841 aaactaaatt attaaatcta tctttaccaa agttacatgt agataagctt atggtgtttg
     9901 atatagttca aaatttgagt tatgaattat ttcaatatgc cttagcttat tttttgtaca
     9961 tgatatgttt ttaatatgag gaaatgagaa gttagttaat atgaataaag aagttaatct
    10021 atttaacaat tatatcgact tgattatgaa aaaatatttt actgatgtcg ataatttatt
    10081 ttatgatgaa gtccatagtc taatattgga tcttcagatg aatttattaa tctatattat
    10141 caataagaaa cgacttttag gagaattaaa gggcgatact cctgaagagc ggtataaata
    10201 ttttaatgaa gttttatgtt caaaaggatt aattcttaaa gagattgagg aaagttatcc
    10261 tgagattatt caacgtacgc agatacaggt aaataaatat ataaagttgt ataaagaagt
    10321 taaagataaa ttttatagag attttgagct actaaaaaag gaaaaattta tcttaactga
    10381 tgattacttt gtagatgata gtaagttatc cattaaggtt agtggagata ttcataatgg
    10441 taaaggggtt tgtattgttt cttactataa tcaaaaagtc gtttataaaa acaaaaaaat
    10501 tgaatcaaat agatttataa ttgatttttt aaaaattatt aacgataaac ttgaagatga
    10561 gatggtttta attcctgatt ttatcggacg tgatggatac tattgggaaa aatatatttt
    10621 ccacaaacag attagtaaca taaatgatgg taaaaaattt tatacaaatt tggggcgttt
    10681 attatgtata tcttatgcat taaatatttc tgatttacat tttgagaatt taattgcttt
    10741 tgggaaatat cctattttag ttgatgtgga aactatttgg aatataggag cttttaaaac
    10801 aattgctaaa gatgattcaa caaaaattct tatagataag aactatgatt ctatattaaa
    10861 cactggactt ttacctattt cttcattaaa tcattcattt ggaggtgata caagtggaat
    10921 tttaggaggt aagtttttag gtgagattcg ggatatagta aacttatatc gtgatgatat
    10981 tcacattgaa cgtaaacaaa taaaaaaaga aaattataat catttacctt ttatagttaa
    11041 gaaatgcgaa gttaactatt tggaaatact agattatata gaggatattt tgaatggctt
    11101 tgatgaagta gggaaaattt taatatgtga tagaggaaaa attgtaaagt tagttgaaaa
    11161 atataaaagt aaaatagaag ttagagtact ttttagaaat acaagggagt acggaattat
    11221 tcaagcatta ctgctttcgc ccgtttattc aaagcaagaa aagcttcttt ttaaaaaaat
    11281 atctcagaaa ttagattatt attctcatga agagttatca ctatctgaag aaaagcaatt
    11341 attaaatatg gatattccat atttttctct aaaggcaaat cagttaacta tttgtgaaaa
    11401 tgggcgtaga gtttggtcat tacaggagac tcctgaacaa aaagtttcta tcaaaattaa
    11461 taaaattagt agagaacttt tggaagaaca aaaaaaatta atcatatttt cgattcaagt
    11521 atcaaaggct ttatattcac ctaagctaaa gcaattgtat tctagatttt tggattattc
    11581 agttaatgta gaagagataa ataagggatt ggaggaactt gttgagagta ttttagataa
    11641 agaagtaatt tcagagaagg atggaacctc gaattggtta acattaacag ttaatgattt
    11701 tgatggttta gaattagaac ctatggatta ttcgatttat agtggaatct ctggggtaag
    11761 tttagcattc ttggaatgtt atgatatttt aaatgataac ttaaaaaagc gtgtgaagga
    11821 aacagttcta agaatttatc ataccattag aaatgcatat aaacagtata gtgataacta
    11881 ctcgttgtac gtaggaaagt taggaatgct aataacgttg aataaaattg aatctttttt
    11941 taatttaccc actaatttag attttttaga tgaattaagg aatatatgta gtaatttatg
    12001 tgatagcaaa aatcctgatt tactagacgg cttatcgagt gttgttgata tcattttttc
    12061 agaggattat ttaactgata atttcagaga agagttggtt gagataaaag aagttctttt
    12121 aaatactgtt tgttttaatg aagatggaaa tgcattttgg aataaagatt ctaaacccaa
    12181 tgtcagttta gcacatggta atttaggaat tgagatagca ctattagagt tatatattct
    12241 acttggggag cctaaaataa aagaaatttt tatgaaagca gttaattttg ataattcaag
    12301 aaagttaaat caagggtggt tagatattag gaattcttca catagtgcaa attggtgtca
    12361 cggttcaaca ggcgttttaa tatcaagaat aaaattatta caaatgcatg attgtcatag
    12421 ttgcttgagc aaaaatgaaa ttattatgtt tattgatgat atacaacatg cgattgaaga
    12481 tatacaggaa gttggaattg aaatgactaa tttttcttta tgtcatggag tgtgtggaaa
    12541 tttgctgtca ctttcatact gtataaggaa tgatattcca attaacttaa aaacatttat
    12601 aaattcaaat tttttattag ataattttag taaattaaat tgtttcggtc aaaaaaatgg
    12661 atggatgtgt ggatatggta caagttatga atcgttggga ctttttacag gcatatcagg
    12721 tattattttt gcaaatgcga agtttttaaa ggaatcaatg atatcaaaaa gtagtttact
    12781 tgacatataa ttgtaataag aaaaggtgat gtccatgaag attattctac aaaataatga
    12841 ggaagattgt ctgctagcct gttatactat gttgttaaat gatttgggaa ttaatattcc
    12901 tttatatgaa gtgtatacta aagattcctt accggcagat ggtcttaatt tgtcttatct
    12961 tttaacattg aataatcgat ttaatgtttt tataaagggg ttccatgctg attttgataa
    13021 tttgtataaa atctacaaag aaagtcggag aagaatgatt cttcattgga atcaagatca
    13081 ttttgtagtt gctgaaaaaa ttatgactga tagagtaata attgtcgatc cagcaattgg
    13141 aagagtacag tatagtcgtg aagaattttt gagccattat tctgggacac tggtactagt
    13201 tggcaagaac gataattttc aaagaatgaa gtgtaagcca attttttgga aatattttaa
    13261 acaaacatta aatgtaaagc caattatttt atttgtaatt tctctactat ttgtccaatt
    13321 aagtgtttta ttattttctg tgactatacg tcaaatgaca tcaaaagact atgcatattg
    13381 ttcgagttta tttcttttag gtagtgttat tatttttcaa atattaggat tttttataaa
    13441 gaatagcgct ttggataagt acaattcaga ttttgatgtt ttttatagta aatcactttt
    13501 tcaaaaatta ttagaaaagc cactcctgta ttttagaaac catttgagcg gagaaatttc
    13561 tgaaaagatt aattttaagt caagtttaag agatagtgtt acactaaaga ttattccttc
    13621 atgcgttagt tttatatctg gtattgcgat tttcttctac ttgatgacaa tttcagtgaa
    13681 tttaacattc attcttgtag ggattatttc tatctatggt ataatttctg caacaattta
    13741 tttaaaacaa attgaataca atcagacgta cttacagtat ttgattgatt ttaattcaga
    13801 atttcagtta gatatagatg atattgacta tatcaagatt atgagacgag aagaagtagt
    13861 gtttaattct tggatgacaa ataataaaaa agttacagaa aaatattcta atattattaa
    13921 aattgaaagt ttatcacagt taattggtac tatatttaat tatttgagtt tgtcatcaat
    13981 aataattatt tctatttatt gtaaagatta tgtaaaaata tcattttcgg atttgttagt
    14041 ttatcaaacc agtatttctt tgttgatatc agcgattgag cagattaaga atgcgatttt
    14101 tgaagttgtt cgcttaggta tttacgcaga aaagcaaagt gatttattga aagatagtaa
    14161 accgattatt gtaccgaata ctaatttaga tgagtactta ataaaggcag aaaatttaaa
    14221 ttttacgtac gatatccaac caatttataa ggatattaat ttaacaattc ataaaggaga
    14281 aaaaattgct attttaggta gatcaggtag tggaaaaaca actcttttaa tgcttttagc
    14341 tggagtattg cgctacagtg gttcattaaa atatggtgta gagaattttg aaaagtattt
    14401 gagtattgtt ctacaaaata tgactcttcg aaaggggagt attttagaca atttagaatg
    14461 gagttcggat aatttgagcc cattatacaa agttctagaa gatacttcag ctgataaaat
    14521 tatcaacaat atgccaaata aaatttattc gaagatttta aagcagggta aaaatctttc
    14581 aggcggtcag attcaaaaaa tacttattgc aaagtcgttg ttgaaaaaag aagcaattat
    14641 attttgggat gaagttttta gtaatttaga tgaggaaagt aagaaaaaaa tttataaaaa
    14701 cgttctgcaa agtagctatt attcagatga aacaatgctc atagtaagtc atcatttgga
    14761 tatagttgac tatgttgatt atgttatttt tatagacgat actactggtg aggttataaa
    14821 agatagtcat agcaatctat taaaaacaaa tagaagatat tcggaattta taaattctaa
    14881 aaagttaagc taggatttgt agaaaattaa tcttatcttt atcttttata ggtataatca
    14941 cttgtataag aaagggttga gtcagtaggt ttgcagaaag gtaaaaaaga tgaacaatat
    15001 tattgaacta aaaaatctta ctaaagttta caaagatatc acgacagtaa atattgaaag
    15061 aatcactgtt cgccggggag aaatttacgg atttttaggc cccaatggtg caggtaagac
    15121 aacaacaatg aagatgattt tatctcttgt ttcaccatct tctggtgaaa tcttagtaaa
    15181 tggtaaagat attaagaaag attatgacta tttaagtcag attggatcga tgattgagga
    15241 gccatcttat tatccaaatt tgacaggata tgaaaatttg ttggttttcc aaaaaatgat
    15301 tggatttgat aagaataata tttggccaac tttgaaacta gtaggattag ctgaagaaaa
    15361 gaatcggaaa aaacttgtaa aagcatattc tttgggaatg aaacaacgct tggctttggc
    15421 gtttgcgtta gtaaagaaac ctagtatttt acttttagat gagccaacta atggacttga
    15481 tcctgctgga attcatgaaa ttcgtgagct aattttaaaa ttagccaagc aagaaggatt
    15541 aacagtcttt atttcaagtc atatattatc tgagattgag catattgctg atcgagtagg
    15601 aattattaat catggtcaac ttgtctatga aggtgaaata gaaaaaatta aatcaaatac
    15661 ctggattaag attggtggtg atttttcaca taaaaatata gttcaagatt tgttgaaatt
    15721 tggcgatttg cacataatgg gggcttctac aaatcatata aagattggca atattgaaga
    15781 tgatatatta gcagatgtcg taactttttt ggttgaaaat ggctatcgta tttttaaggt
    15841 tgttcgtgag aaagaaagcc ttgaagatat ttttctttct ttaactaggg aggtttaaat
    15901 atggtaaaag tcattcaaat tgaattatta aaaagtaaaa gaacgaaatc ttttatgata
    15961 tcgtttgtaa taatgctagt ggcagttgtt tggtctttgc tcgcagcttc tagaagtatt
    16021 aactctccta agttaagaac gatgggatta ttttttaata atcttcaggc aattcctgtt
    16081 tttttaccta ttgcaacctg tttatttgtt tctcggattg taagtaatga aaaagatggc
    16141 aatactttaa aacttcaaaa ttcaaataat attaagttga tgacagtgtt caatagtaaa
    16201 ttattttttt caaatgttgt attttttgtg ttaaatatct ttcaaatatt gatagtctat
    16261 ttggatacag ttagccatga tattgaggca cctctttcta atttggcttt acaactaatt
    16321 gggctaacaa tgtctagctt ttcattgtta acaatttttt tatacctagc tatgatactt
    16381 gagaagcaag gtgttttatt gggaattgga tttttatctg gctttttggg gataataatg
    16441 tcagaaacat caaagtggtt aaatcttttt ttcccttttg gaggttcaag ttttttggcg
    16501 ctatatcgta ttaaagtttt gcagtcgggt gagcatttag attatgtttt tgtttgggat
    16561 aaaacagttc cattaaattt tatattgtac tttatttatt gtatcttgat ttattttatg
    16621 gttaggtatc tattgcttaa aaaacagggg gagaattatg cttagttatt ttaaagctga
    16681 atggttaaaa actcgtaaaa tagctatttt atccgttggt ttaattttct tagctttatc
    16741 aagttttatt ggtcttgcaa atttttttat taattataat gttttaattg ataatcaaat
    16801 gagcagagta ctttgggggc agttaacttt ttataatgct caactactat ttcctgctat
    16861 gttagccatt ttttcaggaa tgattattat acctgagttt gaacgtaaaa cacttgaaat
    16921 gttacgtgtt aattgtatat cgattcctaa attgattatt aataaattgg tgttatcgtt
    16981 gattttagta gcagcaattc aaggactatt atttttaatt tatttagtaa ctcttctgat
    17041 aagtcaaaca tcgtttaata tttctgattt attattattt tttaaagcga caattttatc
    17101 tattgtaggt tctagctcaa ttttaatgat tcattactat attgtgtcta aaacaaaaaa
    17161 ttttgctaag tctgttggga ttgctgcaat aggttctttc attggtttta tttttattat
    17221 gctaggagga gtgttaaata aattttttcc ttactcacaa ccaatgattg cgttaaggag
    17281 taggtcgtta gatagtatga gtgccactga gttgattatt tttatccttg ttaatatttt
    17341 ttatacttat attttctata gattaacagt tcaaacttta gtgaagaaac agtaatgact
    17401 tattgaaaat ccataaaata ctatatattg tttaaaattt gatattgatt gctctttatt
    17461 ttgcagaata ttcagaaatt agtttcaaaa atattttatt atggagtcgc tttctgatat
    17521 aataaaagaa atatattttt tggagaatga tatggcaaca attatagatg gaaaagcttt
    17581 agccgtcaaa aaacagactg aattagttga aaaagttgaa aaattaaaag ctgagatggg
    17641 tgttgtgcct ggtttggtcg ttattcttgt tggtgatgac ccagctagtc aagtttatgt
    17701 ccgaaataaa gaacgttctg ctaagaaagc aggattttta agtgaaactg ttcgcctttc
    17761 agaatcaatc agtgaagaag aattgattca agtgattgaa caatataacg aagatgaccg
    17821 tttccatggt attttggtgc aattgccact tcctgcacac attaatgata agcgtgtgat
    17881 tctagcaatt gaccctaaaa aagacgtaga tggtttccac ccaatcaata caggacacct
    17941 ttggaatgga cgtcctgtca tggtaccgtg tacgccagct ggcattatgg aattgcttcg
    18001 tgagtatgac attgatttag aaggtaaaac agctgtcatc attggtcgtt caaatatcgt
    18061 cggaaaacca atggcgcagc tattattgga caaaaatgca acggttacct tggcgcattc
    18121 tcgcacacgt catttggcgc gcgtgacaaa acaagcagat gttttgattg ttgcaatcgg
    18181 acaaggtcac tttgtaacca aagaattcgt caaagaaggc gctgtggtta ttgatgtcgg
    18241 catgaatcgt gatgaaaatg gcaaacttat cggagatgtc aagtttgacg aagttgaacc
    18301 attagcaagt tatatcacac cggttcctgg tggtgttggt ccaatgacga ttacgatgct
    18361 tttggaacaa acttatcaat ctgcacttag aagcgtgaaa gcatgattat cgacgataaa
    18421 ttagccagaa aagttgtgac aaagcgcaag gcagattctc ataaaggaac ctacggacgt
    18481 gtgcttttga ttggaggatt ttatccttat ggaggagcaa tcatcatgtc agctctagca
    18541 acagtaaaaa gcggtgctgg tttggtgaca gtggcgacag agcgtgacaa tatccctgcc
    18601 cttcatgcac atctcccaga agctatggcg tttgactatg aggatgaaga attactggca
    18661 gaaaatctgg ctaaagcaga tgtggttttg attggccctg gtttagggga aaatagcaaa
    18721 gctaaacatg tgtttgattt tgtactttca gaagcagttg aaaagcagat cttgattgtt
    18781 gatggctctg ctttaaattt acttgcaaaa gctatgccga tttctattaa gacatgtcac
    18841 cttattttga caccacacca gaaagagtgg gaacgattgt ctggactagc aattgctgat
    18901 caaagcctag agaaaactca aacggcgctt gaaaaatttt caaacgggac aattttagtg
    18961 gctaaaagtc atcacacaaa aattttacaa ggtagccaag ttgctgaact agcagttgga
    19021 ggtccttatc aagcaactgg tggcatggga gatactcttt gtggcatgat tgcaggattt
    19081 gtcgctcagt tcaaggataa tctttttgat acggttgctg tagccactta tttgcactca
    19141 gcaattgcag agaaacttag ccaagaggct tatgttgttt tgccaacgac cattagtgca
    19201 gaattgccaa aagtcatgaa acaattatcg gaataatgtc gtaaggtaca cttttcttct
    19261 ggaaaagtgt acttttttag ttcaaaaaac acgtataaaa caaaatgttt caaaaatgtt
    19321 acaaatatta catttttgtg ttgacttaac tgaaaaacta ctctataata ttttcagaat
    19381 tggccgattc taaaaaaata aagtcaaata aacgttgaaa tataaatgtt tatatgatta
    19441 attgatttaa ttgtctggga gattttttat gaaaaaggga tgtaaaacaa ctgtaatatt
    19501 actatcttca ctctttttac taggagcttg ttcaaaaaac gaaaaaggaa catcagcaag
    19561 tagtagtcat gctaaggtga ttcaaacaag taatagtact gctgcaaaga aagttgtaaa
    19621 atctagtgct tcaagctatc aagaatcagt agtctcatca tcttctgtta cagaaatcga
    19681 gccaacagta ggtgtagctg aagtggtaga gactacacaa acattgccta gtcaaagtca
    19741 gtcaagttca aatgaagata ggcttgattt agaacaaatt gcatatggtg atttttctag
    19801 cctttcaggt acttggacaa acgatttggg agaatcaata acactaacac aagatgggca
    19861 agtaagtctt tcgcaaagtc aggcgctgta tcaaatcaca acaaatatcg ttaaagatga
    19921 tgtttatttt ggaactatct ataatcctgg ctcgatgact gatagcgcag catttattgt
    19981 ggttccaaat ggagttgctg atccgtttct aggcgaggtt ggaacgaatg atagacttat
    20041 tgttggacaa tgtgggtctg catctgagca tccatttttc aaacattaaa ttggaatttt
    20101 aagggagaga aattttgaaa aaagtatatt aaatttggga gactgctaag taaaatgaca
    20161 tttcatgaag ttcactataa tatgggtaaa tttcgtatat tagttatggt ggcataagac
    20221 gttatgtatt gctagattaa aaggagaagg gggcttctgc caagggttaa actggcagag
    20281 gtaggtttta gaaaagggaa atgcgaaaga agttttcaaa aaaagttctt atcttacttt
    20341 tgacttttgc taacctagtg gttggctata gtctttgtcg acaattaatg gttattcgtc
    20401 aggaatctga tgttaagatt gatgtatatg cttttgataa aaatgttaaa aaatctcaga
    20461 agaaaattta tcctgattta tcagagcttg accatttgag tatcttggtg tctatttctc
    20521 aacaaaaaat gattgtatac tcagggaata aagtgatttt taaaaccaag gtttcgactg
    20581 gcgccaaaga gacgccaaca ccgacaggca aatttgctat tgaagcagaa cgtggtgaat
    20641 ttttgtatga tgatagtttg aatcgaggtg cgtgtgattg ggtatctttt aaagatcatg
    20701 gcggttatcg atttgaaagt cttccaacag attggaaggg gaaaatctta aagggagaat
    20761 ctaaaaaaat tggaacggct tgtacagatg gcaatgtcag acttttaaaa gaagatgcaa
    20821 aatggctttt tgaaaacatg ccagagggag tgattgtgag tattcactag aactgtccac
    20881 tggacataac tcgcttttag atttctgtgc tcgtgaaaaa actgtccact ggacgtaact
    20941 cgcttttaga tttctatgct cgtgaaaaaa ctgtccactg gacagttttt ttctgttata
    21001 ataataagtg atatgcaaaa tttgtgtaag gcaagaaaaa acaaggaaag gggcctgtga
    21061 tgtcagatta tttaagtgtg tcaaccttga caaaatacct taaattgaag tttgatcgcg
    21121 atccttattt ggaacgggtt tatttgactg gtcaggtttc taattttcgt cgtcgtccga
    21181 cgcatcaata tttttcttta aaagatgaaa atgcggtaat tcaggcgact atgtgggctg
    21241 gaacgtttaa aaaacttggt tttgagctgg aagaaggtat gaaaatcaac gttgtgggcc
    21301 gtgtccaact ctatgagcct agcggctcat attcaattat tattgaaaaa gcggagccag
    21361 acggtattgg ggctttagcg gttcaatttg aacagttgaa gaaaaaacta gctgaggctg
    21421 ggtattttga tgaccgtcat aaacgtcaat tgccgcaatt tgttaagaaa attggtgtgg
    21481 taacgagtcc aagtggagcg gttattcgag atattatcac aaccgtatcg cgtcgttttc
    21541 caggtgtcga gattctactt ttcccaacta aggttcaggg tgaaggtgct agtcaagaag
    21601 tagcagataa tattgcaaag gcaaatgaac gtgatgactt agaccttttg attgttggtc
    21661 gtggtggtgg ttctattgaa gacctttggg catttaatga agagattgtt gtccaagcaa
    21721 tctttgaatc acgtttgcca gttatttcta gtgtcggaca cgagacggat acgactttag
    21781 cagattatgt tgctgaccgc agagctgcaa ctcctacagc agcggctgaa cttgcaacgc
    21841 ctgtaacaaa agctgatatt atttcttgga ttgctgagcg tgaaaatcgt atgtatcaag
    21901 cgagtcttcg tcgcattaaa caaaatcaag aacgtcttga taagttagcg aattcagtta
    21961 tttttagaca gccagaacgt ttgtatgatg gttacgttca gaagttagat cgtttgacga
    22021 tgtctttgac aaatacgatg caaaatcagt ttagtcaagc taagcaaagt catgcactct
    22081 tgcatcaacg tttgcttgcg cttgattttg aaagtcagat caagcactat caggataaat
    22141 tgcagagtct agagcgtttg ctactttcaa atatgactag tcagtacgat agtaacctag
    22201 cacgatttga aaaagcacaa gatgcgttac tttctcttga tacgagtcga attattgcca
    22261 gaggctatgc tgtggtgcaa aaaaatgaaa aagtcatctc aagcgtgagt gatgtaaaag
    22321 tgggagacca gttaacgatt caattgaaag atggtcaact tgaagcggag gtaaaagatg
    22381 ccaagtaaga aaacatttga agaaaattta caagatttag aagcgattgt gacaaaactt
    22441 gaaaacggag atgtggcttt agaagatgct atctctgaat tccaaaaagg aatggttttg
    22501 tcaaaagaac tgcaaaaaac attggatcaa gcagaaaaaa cacttgttaa agtcatgcaa
    22561 gatgatggag tagaaacgga attagatgcc taatggataa agttaaaaaa attggtcaag
    22621 ccattcatcg ttattataaa caaaaagata ttgtgtcacc agatttgatt gaagctattt
    22681 tgtattcagt tgatgcaggt ggtaaacgtg ttcgtccttt gattttccta gaattgcttg
    22741 aaggatttgg agtagtacta acagatgctc actatgatgt ggctgctgcc attgaaatga
    22801 ttcacacagg aagcttgatt cacgatgatt taccagctat ggataatgat gactatcgtc
    22861 gtggacgttt gacaaaccac aaaaaattta atgaagcgac agctatttta gctggagata
    22921 gtctcttttt agacccttat gatttggtgg caaatgctga gctatcagct gaagtgaaag
    22981 ttgctttgat tgctgaattg gcacatgctt cagggacata tggcatggtc ggtggccaaa
    23041 tgctcgatat ggaaggcgaa gagcgcaagc tcagcctctc agagttacaa ttgattcacg
    23101 ccaacaaaac aggaaaatta ctgactttcc ctgtagttgc agctggaatt gttgctggtc
    23161 tagcaggcga ggatattaat aatttacgta aagcaggtag tttgattggg cttgctttcc
    23221 aagtgcgtga tgacatttta gatgtgacag caagctttga agaaatcgga aaaacaccga
    23281 aaaaagactt gttagctgat aaagcaacct atccaagctt gcttggttta gataaatctt
    23341 atgatatttt aaatgagtca ttggatgaag cgttagctat tttccaaaaa ctctcagaga
    23401 ctcaaggatt acagacagaa aaaattgcag aattgataga aaggttacga ctaaatgcct
    23461 aaggaaagag ttgatgtact tgcctataaa caagggcttt ttgaaacacg cgagcaggca
    23521 aagcgtggtg tcatggcagg cttggttgtt aatgtgatta acggcgaacg ctatgataaa
    23581 ccaggtgaaa agattgatga tggaacagaa ttaaaactaa aaggcgaaaa attgaagtat
    23641 gttagccgag gagggctaaa acttgaaaaa gccttgcaag tttttgagat ttctgttgat
    23701 ggtcaaacaa caattgacat cggtgcctca accggtggat ttacggatgt tatgctacaa
    23761 aatggagcca aattggttta tgctgttgat gtaggtacaa atcaattggt ctggaaactt
    23821 cgccaagacg aacgtgttcg cagtatggaa caatacaatt tccgttacgc tgaattggct
    23881 gattttacag aaggtcaacc aacttttgct agtattgatg tgagttttat ttcattgaat
    23941 ctcattttgc cagctcttca caatatttta gctgaaaatg gtcaagtcgt agctcttatc
    24001 aaaccacaat ttgaagctgg tcgtgaccaa attggtaaaa atggaattat tcgagataaa
    24061 gcagttcatc aaaaagtttt ggaaactgtg acaagttttg ctgtcgatta cggatttaca
    24121 gttaaggggc ttgatttttc accaattcaa ggtggacatg gtaacattga gtttttagca
    24181 cacttggaaa aatcagctaa cgctcagaat ttggtagcga ctcttatccc agaaattgta
    24241 gaaaaagcgc ataaggaatt taaagatgaa aaagagtgaa cgtttagaat taattaaaaa
    24301 gattgttgct gaaaatgctg ttgaaactca gcatgatttg ttgaaattac tcgaagctga
    24361 aggtttgact ttgactcaag ctaccatttc acgtgacatg aacgaaattg gtatcatcaa
    24421 agttccatca gttgatggtc cgtacattta cggtctttca aaagataaaa ctaaaaaagt
    24481 gggacaagtt tctgttccga ttaaaagcac agtccttgcg atttcagaag aaacagctgg
    24541 acttgaaaat atgattaatc ttgatgttat tccaggaaat agtcgcttga ttaaacgtta
    24601 tttgctagaa gatttcaaag atagtctttt tagtgttatt gctgatgatg atagtttgtt
    24661 agtggtcgca aagacagctg aagctgctaa tgccattcgc caagaagttc gtaaatggat
    24721 gacagaccac aaataagaaa ggtcgcctat gcttttagaa atttccatta aaaattttgc
    24781 tattattgag gaaatctccc taacttttga aaatggtatg actgttttga ctggtgaaac
    24841 aggtgccgga aaatcgatta ttattgatgc tatgaacctt atgttaggag cgcgcgctag
    24901 tctcgatgtt attcgacatg gtgccaaaaa agctgagatt gaaggacttt tttcggtcgg
    24961 tgaaaatgct gcgctgacac acattttgga agaaaatggt attgatattt ctgatgaatt
    25021 gattattcgt cgtgagattt tgcaaaatgg tcgttctatt agccgtatca acggtcaaat
    25081 ggttaatctg acaacccttc gtgcggttgg acagtacttg gttgatattc acggtcaaca
    25141 tgaccaagaa gaattaatga agcccaacat gcacatccgt atgctggatg aatttgggga
    25201 tgaacatttt tcagctgtca aaaaacacta tcgagaaatt tttgaaagtt accgcacatt
    25261 gcgtaagcgt gttttgacta agcaaaaaaa tgaacaagag cataaagcac gtattgaaat
    25321 gcttgaattt caaattgctg aaattgaggc agcggctcta aaatcaggcg aagaccaagc
    25381 actcaatcaa aaacgtgata agctacttaa tcacaaacat attgctgaca ctttaacaaa
    25441 tgcttacgtt atgcttgatg atgaagagtt ttctagtctg tcaaatatcc gctcagctat
    25501 gaatgatttg atgagtctcg aagaatttga tcaagattat aaagaaatgt ctgcaaatgt
    25561 ttcggaagct tattatatct tagaggaagt tactaaacat ttgggtgatg ttattgaaga
    25621 tcttgatttt gatgcgggta gtcttcaaca aattgaagct cgtttagaag tgatttacag
    25681 catcactcgt aaatatggtg gcagtgtcga tgacgtatta gactactatg aaaacattac
    25741 gaaagaatat aatcttttaa ctggtagtga tgagtcatct gacgatatgg aaaaagagct
    25801 taaacatctg gaaaaagaat taattttagc tgcagatgag cttgctcaag aacgtcacaa
    25861 acttgctaaa gatttagaag cagaaatcaa gcaagaatta gctgatttgt atatggaaaa
    25921 agcagatttt caagtgcaat tcaccaaagg aaaattcaat cgagatggaa atgaagttgt
    25981 tgaattttac atttcgacaa accctggtga aggttttaaa ccacttgtta aagtagcatc
    26041 tggtggtgaa atttcacgtc ttatgcttgc cattaaatca gccttttcac gcaaggaaga
    26101 taagacaagt atcgtctttg acgaggttga tacaggggtt tctggtcgtg tagcgcaagc
    26161 tattgcccaa aaaatctaca aaattggaag tcacggacag gttcttgcaa tttcgcactt
    26221 acctcaagtc attgcgattg ctgattacca attctttatt gaaaaacgca gtgatgaaaa
    26281 tacaaccgta tcaacagtcc gtctgttgac tgaagaagaa cgtgttgaag aaattgctaa
    26341 aatgcttgca ggtagtgata ttactgagat ggcgcgtgaa caagcgcgtg aacttttgaa
    26401 aaaataagaa gaagccaaag tggcttcttt ttgcttgttt aagaaaatat ccccgaactg
    26461 ctaaaaattt ggtataatga atgttagaat aaaatttgaa ataaagtttt gaaagtatga
    26521 taggataaaa aatgagtaaa attaaaattg ttacagattc atctttaacg attgaaccag
    26581 aattagttga aaaatatgat attacagtag tgccattgtc agttatgatt gatggtgttg
    26641 tttattctga taacgatatg aaagaagaag gtaaattcct taatttgatg cgtaatagca
    26701 aggaattacc aaaaacaagt caaccgcctg taggtgtttt tgcagaagtt tatgaaaact
    26761 tgatgaaaga tggtgctgag catattgttt ctatccatat tactcacact ctttcaggaa
    26821 cagttgaagc agctcgccaa ggagcaaatc ttgctggtgc tgacgtgact gtcattgatt
    26881 caacattcac tgaccaatgt caaaaattcc aagttgtcca agctgcgaaa ttagcacaag
    26941 aaggtgcaag tcttgaggaa gttatcgcta aagttgaaga agttcgtcaa aaatctgaac
    27001 tttttatcgg tgtgtctaca cttgaaaatc ttgttaaagg tggacgtatt ggacgtgtaa
    27061 caggtcttct tagctcatta cttaatattc gagtagtgat ggaaatgatt gattgtgagc
    27121 ttaatacagt tatcaaaggg cgcggtgtta agacatttaa caagtggctt gatagcttta
    27181 tcgaacacgc tcaagcttca ggtaaaaaag ttgctgaaat cggtatttca tactgcggaa
    27241 ctgctgatat ggcaaatggc tttaaagaaa aattggaagt tttgggtgcc ccaattgctg
    27301 ttttagagac aggttcaatc atccaaacgc atactggaga agacgctttt gcggttatgg
    27361 tacgctatga gtaataaaaa gaatttttta atcgggtttg ctttcttttt agcaagcctt
    27421 cttctgttta tcgtcgtttt taatctcttg attccaaaat cagatcaaga attaactaaa
    27481 aaggattttc tagctcaaga agctaagcat ttcaattatg tagctgttgg ggattctttg
    27541 acggaaggtg ttggagatac gaccaatcaa ggtggttttg ttccactttt atcccaagct
    27601 atgacagata cctataatta ccaagtaacc tatagcaatt atggaatttc tggtaatacc
    27661 agccagcaaa tcttgtcacg catgaaaaag caagaagcta ttcaaaaatc tcttgctaaa
    27721 gctgatatga tgacgcttac tgtcggtggt aacgatgtta tggcggtgat tcgaaaacat
    27781 ttaacacaac tatctgtttc aacttttaaa aagccagcaa cggcttatca gaaacgccta
    27841 cgtcagatta ttgaattagc tcgctcagaa aatgaagatt tgccaattta tgtcttggga
    27901 atttataacc ctttctactt gaactttcca gaaatgaccg aaatgcagga aatcattgac
    27961 aattggaatg aatcgactga aagtgtcaca gatgagtatg acaatgttta cttcgtgcca
    28021 attaatgatc aactttacaa aggaattgat ggcgaagaag gaatagtgtc aacgtctggt
    28081 gaccaaacga cagtcatcaa cgatgcttta ttcagtggag accattttca cccaaataat
    28141 attggctatc aaattatgtc agatgtaaca atggagaaaa ttaatgaaac taaacaagaa
    28201 tggaacaaag actaattggt ggaagtgggg attccttctc attttagcca ttaatgttgc
    28261 ttttgtagga gtgattgcca gtcgcctgat tcaagtcaga gagcctgcag ctcaaagtat
    28321 aagctctaaa aaggctgata atgtcaaagt tggtaccatt tcaaccacac gtgagcaatt
    28381 aaatgatacg gtggcatcat acttgaagga gtaccagact aaaaaaacgt cttacagtgt
    28441 ttatgcgaca tcttcagcga ttatgtttga aggaacgtat acatttttag gatatgaggt
    28501 gcctttgtac atttattttc aaccaagtcg cttggaatca ggtgctattc agttgaagat
    28561 tacgtcgttt tcagttggaa ctcttacatt accagaatct gaagttttga agtatctaaa
    28621 atcaagtatc aatctgccag attttgtgga agttttgcca aaagagtctg tcattaacat
    28681 caatattcag gacataaaaa acgatgcaga tatctttttg aaagcgacaa caattgacct
    28741 tgtcggcgac caatttaact ttgatattta caagaaaaac agctaaaaaa acgtttaata
    28801 cttgaccaga atagtatttt tgggtatcat agaatttgtt aaagtgttaa cgcttagaaa
    28861 ttaattggag gatttgttaa atggctaaca aacaagattt aatcgctaaa gttgcagaag
    28921 caactgagct tactaaaaaa gattcagcag cagctgtaga tgcagtattc tcagcaatcg
    28981 aaagcttcct ttctgaaggc gaaaaagttc aattaatcgg ttttggtaac tttgaagttc
    29041 gcgaacgcgc agctcgtaaa ggtcgtaacc cacaaactgg tgaagaaatt gaaattgcag
    29101 cttcaaaagt acctgcattc aaagctggta aagcacttaa agacgctgta aaataattaa
    29161 atagaaaaga accttgtcta ttgacttctg ttgatgtgac agggttcttt ttgccatata
    29221 agacaaattt cgagtgctga caaaagtgtt ttgatgattt atgttataat caatttactg
    29281 atgaaaaata gaaagaatta taattatgga taaatcactt ttgcttgttg ttattttttt
    29341 aggagccttt tctttattca aagccgctat gttaattatg gttggcatgg caatgaaacc
    29401 gaaagttgat gaagatggca acattgtgaa accagtggag gaagaagacg aagagaaaca
    29461 accttcaatt aacgaggatg acagcgattt ttgggataat tggtgatgaa aaaaacgtcc
    29521 agtggacgtt ttttttatga gccaagaaat tcgaaagcga gttgagtcca gtggacgttt
    29581 tttcatgagc taaaatcggg gtgcaatgta tccagctaac tttttacgca attctaaggc
    29641 aattgaagaa agttagtgat aaaatgcacg tttgtgaaat ttttcaaaac ttgtttaatt
    29701 atgcagtaag aaaaaaatga atagttgatt acactggcaa aaagggtgaa aaattaggga
    29761 ttttcggacc ttattaatat aaaaatttca aattatgtga aaattttgta ttgctaaact
    29821 aaacaaagac cattataatg gatagtatgg aaaataataa aatagaacaa actttttttg
    29881 gacaacctaa agctttgttt acactattcc aaacagaact ttgggaacgt ttttcttact
    29941 atggcatgcg tgccatcttg atttactact tgtatgcatc agttactgcg ccaaacgcag
    30001 gtttgggact tcctaaacca caagcgatgg cgattgttag tatctatggt gcattagtat
    30061 atctttcagg tattattggt ggatggttcg cagaccgtgt tctgggagca tctcaaacaa
    30121 tctttatcgg tggtattctt atcactcttg gtcacattgt tttagccgtt ccttttggat
    30181 taacatctct gtttatctcc cttttcttca ttatcttggg aactgggatg ttgaaaccta
    30241 acatttcaaa tatggtcggt cacttgtatg ctgcagatga cccacgtcgc gatacaggat
    30301 ttaacatctt tgttattggt attaatattg gttcattgct tgcgccgatt gtagtaggta
    30361 cagttggtca aagtatcaac taccacctag gtttctcact tgctgctatt ggtatggtgc
    30421 ttgcattgtt cgtttactgg tttggtcgta tgaaacaatt cccagaattg ggaaataaac
    30481 catcaaaccc aatgacttca gcagaaaaac gaggattatt agtaaaatta gctatcggtc
    30541 ttgttatttg tgctgttggt ggaactttcc tttaccgagc aaacccatct aattttgtta
    30601 ataatctagt taacattctt tcaatggctg gtatcttcat tccattcatt tacttcgtta
    30661 tgatgtttgc ttctaagaaa gtgtcaagca ctgaacgtaa acaattgttg gcataccttc
    30721 cattgttctt gtcatcaatc atcttctggt tggtcgaaga acaaagtgca acagttatcg
    30781 ctgtttgggg tgaaactcgt tcaaacttac atccaactat ctttggaatg aacttgtaca
    30841 ttgatccatc atggtaccaa ttgcttaacc cattgttcat cgttgcttta acacctgcct
    30901 tcgtatggct ttggaacaaa atgggtgaac gtcaaccttc tccagtaact aaatttggac
    30961 ttggtctttt gttaactggt gtttcatact tgattatggc gttgccaggt atcttatatg
    31021 gaactgataa acgtgtaagc ttcatgtggt tggttatcat gtttgctgtt caaatggccg
    31081 gtgaattgct tgtttctcca gttggtctat ctgtttcaac tcgtcttgca ccacttgctt
    31141 tccaatctca aatggttgct ctttggttct tggcagattc aacttcacaa gctgtgaacg
    31201 ctttgattac accatacttc actaaagaaa cagaagttgc attcttcggt attttaggtt
    31261 tggtttgtct tgctgtaggt gttatgctac tcttcatcaa caaacctgta ttgaaattaa
    31321 tgcgtaacga taaataataa aataaaacaa agaggttttt gtcaattaat aggaggtgac
    31381 aatcaaaacc tcgagcgaga acaaatgttc tcgctttttt gttgctcgaa gttaagaatg
    31441 ttcactaaaa caggtagtac aaaatcttta tgacctgttt ttttattaat caatgtaatg
    31501 taattttccg cggaagtcat ctagtgtttc atagcctttt tcttccatga tagctttcaa
    31561 ttcgtcagtg atacgtgcaa aagcagcagg accttcttgg tgtagaattg ttccgagttg
    31621 aaccatgctt gctccgcaaa gaatatgttc aaatgcatcg cgaccagatt tgacaccacc
    31681 agttccgatg atttggatag atggatttaa acgtttgtaa aatgcgtgaa cgttagctag
    31741 tgcagttggt ttaacataat caccaccgat tccaccaaaa ccatttttag gcttgataac
    31801 aacagtctcg tcgtcaatga ctaagccgtt tccaactgag ttaatgcagt taacaaaagt
    31861 aagtgggaat ttgttaaaaa tggcagcagc tctgtcaaaa tgtgcaatat caaagtaagg
    31921 tggaagtttg acaccaagtg gttttgtaaa gtatgtgaag atatctgtta agattctttc
    31981 agtggtttca aagtcgtagg cgatttgtgg tttgccaggg acatttggac aagaaaggtt
    32041 taattcaact agtccttgat aatcagaagc ttggacagct ttcaaaatag tatgagtttc
    32101 ttcttctgac ataccaacaa gtgacaagaa gtgatttttg ctttctgggt tattttggag
    32161 ttctgtgaca taatcaagat aatattgata gccatggttt ggtaagccca tagaattaat
    32221 tgaaccaagt gcagtatcag cgtaacgtgg ttcaggattg cctggtcgtg caacgagcgt
    32281 tcctgttttt gtcacaaaag aaccagcagc tgaatcttca atctcagcca attcttcacg
    32341 tgtcatacaa taaacgccag cagcattcat aaggcaatta tcaaaatcga atgaaccgat
    32401 tttagtagca gttgaaacca taaagtcctc caagatatat taatgaaagt gacaaatgtc
    32461 ctaaaatatt actgctttca ttgtactatt ttatagatgc aaattcaagt gttttccgaa
    32521 cgatattttg taatatgtgt aaaaatagaa agatttagcg aactgaatag aataaaagat
    32581 acttttgtag caaaaaaatg gcacaaaaaa ggaatgaacc gaaattttgc tgatatgaat
    32641 gtaaagactt gctagcattt tataaaagtg gtatatttat cttgttagaa catttgagca
    32701 aatgttcaag tgttctaatg atagaggaga agaataatga aagataataa taaatcacaa
    32761 aacttgctac agggtgattt gttaaacaat gtttctagtt tttttaaagc acttggaaat
    32821 actacgcgtt tgcaaatcat ttgttgctta agtaaaggtg agctgaaatc tagcgaatta
    32881 gcagaaactc ttggaatgac accgtcagct gtttcgcatc agttgagtct gcttaaaaat
    32941 ctcaagattg tttctgttcg tcgtgatgga aaaaatcaga tttatgccct tgctgatagg
    33001 catatcagtc aagttttgga gtctgttgta gagcattatc aggaggacta aagatgtcag
    33061 ataaacataa aaaatccctt tatcggattt tgctagcaac gctagttttt attgtcgttt
    33121 ttatcattgt gaaggttagc cgtgctaatc tagtattaca ggcacttctg tatgctattc
    33181 catttttgat ggctggctat gatgttttga aaaaagctgt gctgaaaatc agtcaaggta
    33241 aagtctttag tgagcatttt ttgatgtctc tagcgacgct tggagcattt gcacttagtt
    33301 ttatgacggg agaatcagag tttgcagaag cagtatttgt tatgattttc tatcaagtcg
    33361 gtgaattctt tgagcacatc gcagaaggaa gtagcgagaa atcaatttca gaattgttaa
    33421 acttgcgacc agatttggtt catttagaag tggatggtaa ta
//
