LOCUS       NZ_FMVM01000017        23862 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Paenibacillus polysaccharolyticus strain BL9, whole genome shotgun
            sequence.
ACCESSION   NZ_FMVM01000017
VERSION     NZ_FMVM01000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polysaccharolyticus
  ORGANISM  Paenibacillus polysaccharolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900102085.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 18:13:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,652
            CDSs (total)                      :: 5,587
            Genes (coding)                    :: 5,563
            CDSs (with protein)               :: 5,563
            Genes (RNA)                       :: 65
            rRNAs                             :: 6, 5, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 3 (16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 6 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:28:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 159585
            Orig. end                         :: 183447
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMVM01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..23862
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23862
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:23705](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..23705
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     misc_feature    592..606
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.73"
                     /tool="antismash"
     misc_feature    complement(720..733)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.8"
                     /tool="antismash"
     gene            complement(890..2407)
                     /locus_tag="BLQ13_RS22560"
                     /old_locus_tag="SAMN05720606_117153"
     CDS             complement(890..2407)
                     /EC_number="1.1.1.58"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689260.1"
                     /locus_tag="BLQ13_RS22560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117153"
                     /product="tagaturonate reductase"
                     /protein_id="WP_090923928.1"
                     /transl_table=11
                     /translation="MSASTKRPRLKMHLLGNDSQRKCKEMIERPVKVLQIGEGNFLRGF
                     ADWMLHESARQGKFHGSVAVTQPRPGGKAKLEQIRDQDGLYTMITRGLSEGKRVERTEM
                     VSVFSQFINPYEEWQTFLELAELPSLEFVISNTTESGLKYIQSDYIPGEPVQSFPGKLT
                     VFLHQRYVRFAGDPSRGLIHLPCELLEGNGDVLRECVLRHSEDFGFSDSFRSWIEHHNQ
                     FLNNLVDRIVTGAPTQEEADALTERWGYEDQLINTAEPYHFWAIQGEESLDKRLPLKQA
                     GLNVHWVKDLKPYQLRKVRILNGSHTLMSSLGLLRGKQHVRETMEDPQFSSWIRQAVLE
                     EIVPAMDMPELGLEPYAEEVFERFLNPYIDHKLQDIALNTAGKFKVRVLPTLLAYEQSQ
                     GSWPERLIQGFAGFLYLYRPLQTQEGYRAQLLSGETIPLRDDPDVLAALATHWEGYDHL
                     TSGTAELEKRVAALLSDEVIWGENLDAKEGLRAALVHEISKLEGEVK"
     misc_feature    2544..2553
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            2602..3480
                     /locus_tag="BLQ13_RS22565"
                     /old_locus_tag="SAMN05720606_117154"
     CDS             2602..3480
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014376.4"
                     /locus_tag="BLQ13_RS22565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117154"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_090923929.1"
                     /transl_table=11
                     /translation="MEHSPVRTTIQTESGIPFRLVYSDTKSPQNELPDHLHDWHEIIYV
                     YRGQGSIFIDAGLEDMQEGDLFLIPGSTVHRALPDAGNPVTSSALFFSPGLLASTAGGM
                     SSSLLHPFERCRKRRIYKRHLNHAEQAQVSAFIDDIHAEFRSDHHLSSHAALLRLQLLL
                     IFLERLDSATGPALATSSLPTPSWLSSILSDIDLKLRNRLTLPELAQQAAVSPAHLSRA
                     FKRYTGMTLTDYVLARRVIMAKEHLLNGDETMAAVADACGFDSLPHFYRQFKKLTGTTP
                     AAYRRTMVQHR"
     gene            3584..4261
                     /locus_tag="BLQ13_RS22570"
                     /old_locus_tag="SAMN05720606_117155"
     CDS             3584..4261
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425767.1"
                     /locus_tag="BLQ13_RS22570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117155"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_186809553.1"
                     /transl_table=11
                     /translation="MIIKFLIFGLLWQIVGNPFIAILILLVILYFLDRRFVGVFPSFTK
                     PLKRLRNISRLKQQLALNPNEVSSKLELARLLIERKRYSEAHAFLLELERPYEQSAEYW
                     EALGTTELYLGKISEGERHILHALEINPRVKYGQPYLNLATAFKDTDRDKALHYVQQFQ
                     EIHSSSSEAFYLLGSVYRSLGRNEDAKQAYDQSLNVYRSLPKYKKRQERRWAVRSWFRK
                     RAL"
     gene            complement(4373..5488)
                     /locus_tag="BLQ13_RS22575"
                     /old_locus_tag="SAMN05720606_117156"
     CDS             complement(4373..5488)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="BLQ13_RS22575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117156"
                     /product="phosphotransferase"
                     /protein_id="WP_167375819.1"
                     /sec_met_domain="APH (E-value: 1.4e-24, bitscore: 80.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNKQQNSLLPKEKQLISEVLALYGFRSDWQGKRSNGGMNNSTFV
                     LHTRDADYVMRQYETHNDQAKIAFEHGVLIALSNTDFKLHSPTPVISLSSSSGKTADQE
                     SKESNHSNEENRQTYQLVQDHITGTFKVVALFRYLEGVNPVWDSPEQLRPLGRAAGNLS
                     TALAKLELELKPVYPPYYRIDEAYPLCSPERLLEMCASPPETLKVCAEELEQLLVELPG
                     LFKALRGMEQLPHQIVHGDVNASNVLVDPEGNMSAILDFEFATWDLRVMELAVPMSDML
                     TMDKSEEWMWQAQANLVQGFREEVELTADELKAIPQLILLRSLDVVMHFISRMLEGTDK
                     PEVATEQIVKLKQRMDWMGRHENQLRQLLTN"
     gene            complement(5575..6237)
                     /locus_tag="BLQ13_RS22580"
                     /old_locus_tag="SAMN05720606_117157"
     CDS             complement(5575..6237)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689264.1"
                     /locus_tag="BLQ13_RS22580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117157"
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_244159419.1"
                     /transl_table=11
                     /translation="MIREISRERGGGMVYRYVAIGDSLTVGTGALLGTGFVPIYRRMAE
                     MNLRTFVSMDNLGVNGLTSAELQQMINGHPRVRQAIREADMITVSIGGNDLIRTFKASG
                     GIPNAGKMTQVLGETRHHVSQVMRQIRQLKGDQKYFVRSIGLYNPYPQSTEAAYWVRQY
                     NSYLNGAGSGNYACAQVYDKFEGRERELLFWDRVHPNARGYRIIAEQLNRTGYVPFA"
     gene            complement(6404..9571)
                     /locus_tag="BLQ13_RS22585"
                     /old_locus_tag="SAMN05720606_117158"
     CDS             complement(6404..9571)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689265.1"
                     /locus_tag="BLQ13_RS22585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117158"
                     /product="MMPL family transporter"
                     /protein_id="WP_090923931.1"
                     /transl_table=11
                     /translation="MRAILKGRWWIMGLWIVAAAVLMFTAPNMSELIREKGQFSVPEGY
                     SSTNAAAILNEAAAQNGEQKGTSIALVFYNPDGLGTTGKQEAEKAVKLLEADKQKLGIL
                     SVLEPFSQPELSDKMISKDGKTILTSLSIEMGDRTVKEMRNDLNDALESVNVEHYITGK
                     GLIDEDTIESSQEGLKKSEYITVVFILLILFLVFRSFVAPFVPLLTVGISYIVSQQIVA
                     FLVDGVNFPLSTFTQIFMVAVMFGIGTDYCILLISRFKEELAHHENTWDAIIATYRTAG
                     KTVFFSALAVLVGFVAIGFAQFMLYRSAVAVAVGIAVMMLALVTIVPFFMAVLGRKLFW
                     PSKGSLEHAESKIYGAAGKFSLKRPWAALLIVAAVTVPLLSTYDGKLSFNSLDEIGDKY
                     DSVKAFNIISDSFGPGESLPGQIVIQNDETMDNAKYMAVAEKISREVEKVPGVAGVRSM
                     TRPTGDEIKDFEVTKQVGTLSDGLGEGKTGLDKISDGLSKASNELSKNEPQLKEAANGA
                     GQLTKGTSQLQSGITQLSDGLKRIEKGIRDGSSGAGDLKAGLQQAKTSADQLAKANDQL
                     LQAYRQAGAGVAALGDGTKELEQQLTGVSTALTSLTASFSALEERFPELQQDADYQRIK
                     GTIGQTGSGTAQLAQGLSQIQTNLSSAAAGINQANEGFASAASGQKALADGLGQIVAGI
                     GQLETGLKQAADGQGKVIKEIPSIQNGLGQLQGGQEKIQKGFSDLSGQLTQLTDGLNQS
                     VDGIKKVSGGLDSAQDYLTQLQNSPDSDLAGWYVPEEALNNKDFKKVFDTYLSKDRKTM
                     TLDVIFAENPYGTEAIDRVPDIEAAVHRAIQGSALEKADVAVGGVTSTFADLQSISNKD
                     YTRTVMLMLAGTFIILVILLRSVIMPIYLIISLLLAYFTSMALTEVVFVNIMGYAGISW
                     VTPFFGFVMLIALGVDYSIFLMDRFNENKGMRVQDAMLYAMKNMGTVILSAAVILSGTF
                     AAMYPSGVLSMMQIATVVLSGLILYSLLFLPFFVPVMVKMFGRANWWPFRNKEQSESSE
                     SNHTVGM"
     gene            complement(9571..10026)
                     /locus_tag="BLQ13_RS22590"
                     /old_locus_tag="SAMN05720606_117159"
     CDS             complement(9571..10026)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689266.1"
                     /locus_tag="BLQ13_RS22590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117159"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_090923932.1"
                     /transl_table=11
                     /translation="MNIPDAKSLVNRYLDASFLVNKRFDTQIREKVGQTVTTDQFCALR
                     LIHEKPACTPSDLAELLCVGKSSITALVNKLADRNLVHRAGDERDRRVIYLTLTEAGLQ
                     IYKETELEIQKVLEPYLKHFTPEAVQNFIESFEKLAALLTQEEGLEK"
     gene            complement(10237..10674)
                     /locus_tag="BLQ13_RS22595"
                     /old_locus_tag="SAMN05720606_117160"
     CDS             complement(10237..10674)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009675431.1"
                     /locus_tag="BLQ13_RS22595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117160"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_090923933.1"
                     /transl_table=11
                     /translation="MLKNLKPRLQEPEVQELLSYAVFPDPDQVNQAVQQYVTQSNLFLT
                     GYEDEGQLVGLIGYEHTGANEITIRHIAVLPENRFKNYGRGMISQLLAEYNPDTLIAET
                     DQEAVEFYRNTGFVVYSLGELYPGVERFRCVLEKEDDEQEA"
     misc_feature    10663..10676
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     gene            complement(10698..11411)
                     /locus_tag="BLQ13_RS22600"
                     /old_locus_tag="SAMN05720606_117161"
     CDS             complement(10698..11411)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014414.4"
                     /locus_tag="BLQ13_RS22600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117161"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_090923934.1"
                     /sec_met_domain="PCMT (E-value: 1.1e-07, bitscore: 25.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEQFEAARQAEAGYHSNFYKNNELFEDGTWMSRPMPMVMEMLE
                     RLLVHKQELRVLDLGCGVGRHTIPIAQRLADTNSEVIGVDLLDEAVDGLRKYAKQYEVD
                     HIVQAEKADVEHYRIQPKAFDFIAACSCLEHTSSKEAFLETVERLKEGTRLGGIHCIMM
                     STSVEEKEIQTGRQIEPLIELNLPTSEVMALLEQAYEGWNILFQEHVTQTIQEEKYDEP
                     TEFRCELLRFAVQKD"
     gene            complement(11454..11783)
                     /locus_tag="BLQ13_RS22605"
                     /old_locus_tag="SAMN05720606_117162"
     CDS             complement(11454..11783)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLQ13_RS22605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05720606_117162"
                     /product="hypothetical protein"
                     /protein_id="WP_090923935.1"
                     /transl_table=11
                     /translation="MPRFSRECSYCHQPMGEDEFKCKSCGNMVTTKTAKPDQPYMSEYE
                     ESTLDRYSMVLLVIMTIFFAPIAMTIGGILLFNDYASKRDAGKILVTASLIMIVIYMIL
                     FFVFR"
     gene            complement(11813..12757)
                     /locus_tag="BLQ13_RS22610"
                     /old_locus_tag="SAMN05720606_117163"
     CDS             complement(11813..12757)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (92-212). E-value:
                     8.7e-14. Score: 43.6. Matches aSDomain:
                     nrpspksdomains_BLQ13_RS22610_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689270.1"
                     /locus_tag="BLQ13_RS22610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117163"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_090923936.1"
                     /sec_met_domain="PF00561 (E-value: 8.4e-12, bitscore: 38.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.8e-10, bitscore:
                     34.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.3e-12, bitscore:
                     40.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFYGLAALIIIIIALLWVGGLYFFKTAIRRTPKTFLADNPNLKT
                     EVEDELISTVGDLQWLDAQDTKTVTIQSQDGLRLSGIWLPSKNKSAKTVILAHGYSGKG
                     REMAGFARFYAETLGYHVLMPDDRGHGQSEGEVIGFGWLDRKDYVQWIGWVLGHVGLNT
                     DIVLHGISMGGATVLMTGGEELPDQVRAIVSDCAYTSVEEELTFQLKQLYKLPPFPFIP
                     VTSLITRWKAGYSFKEASALKQLAKVNVPVLFIHGEADLFVPTEMVYRLYEVCKSEKEL
                     LTIPRAGHGTAFQVDREKYKAVLGAFLQKHMPL"
     aSDomain        complement(12122..12481)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLQ13_RS22610_Abhydrolase_1.1"
                     /evalue="8.70E-14"
                     /label="BLQ13_RS22610_Abhydrolase_1.1"
                     /locus_tag="BLQ13_RS22610"
                     /protein_end="212"
                     /protein_start="92"
                     /score="43.6"
                     /tool="antismash"
                     /translation="TVILAHGYSGKGREMAGFARFYAETLGYHVLMPDDRGHGQSEGEV
                     IGFGWLDRKDYVQWIGWVLGHVGLNTDIVLHGISMGGATVLMTGGEELPDQVRAIVSDC
                     AYTSVEEELTFQLKQL"
     gene            complement(12841..14604)
                     /locus_tag="BLQ13_RS22615"
                     /old_locus_tag="SAMN05720606_117164"
     CDS             complement(12841..14604)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="BLQ13_RS22615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117164"
                     /product="ATP-binding protein"
                     /protein_id="WP_090923937.1"
                     /transl_table=11
                     /translation="MPSDNEEIQRLRKTIEQLSDQLIRSKEQEERTLSAFSDMNNELVT
                     LQRQLSKNNAGLESARQKAVASDESKSAFMAVISHDFRTPLNGILGMAELLTYSPLSEE
                     QKDSVIVIQEAAKLLLKLIQDLLDFSKLEAGQLRLEQGEVKLQEIMDYILRLLKPQIDK
                     KRNRMIMDCDPEVAAVLEGDSTRITQILINLIQNANKFTTDGSVKVEVKLVRQQARTQL
                     VRFEVHDTGIGISEEDQISLFEPYMQTEQGRSKEYEGTGLGLSICKSLVQLMNGEIGIR
                     SKEGEGSIFWFELELGLHMVESKESAQLTVADETSDLTNDAKNDVGDATKNSSKDAPEQ
                     DARTLPILLADDNVINRQLVQLQLKKLGFTELECVSSGEEAVNAFRDKTYSLILMDSMM
                     PVLDGIEAARQIRAIEQDEMRPATPIIAMTGNVMQSEKDKCYEAGMNDFIGKPFTLEVL
                     DTTIRKWHSASKPVQILNMDVVREIAELNTDGSQTLLSMLLEMYRAETPGKIEDLRRHV
                     VSADHKAAAETAHDLKSGSLSLGISYLSTLFSQIEKYAKQELTHQAEPLLDKLLPAYQA
                     ACGALQQANKS"
     gene            complement(14620..15708)
                     /locus_tag="BLQ13_RS22620"
                     /old_locus_tag="SAMN05720606_117165"
     CDS             complement(14620..15708)
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017813590.1"
                     /locus_tag="BLQ13_RS22620"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog.; Presence
                     of a B(12) (cobalamin)-binding domain implies dependence on
                     cobalamin itself, in one of its several forms, or in some
                     unusual lineages, dependence on a cobalamin-like analog.;
                     Presence of a B(12) (cobalamin)-binding domain implies
                     dependence on cobalamin itself, in one of its several
                     forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117165"
                     /product="cobalamin-dependent protein"
                     /protein_id="WP_090923938.1"
                     /transl_table=11
                     /translation="MSHREAGERLLQDAEILAEKITEMQYRLQPDLMERFGPIGKIRTK
                     QDSQYSLSYLAESVLVKSPGLFTHYISWLKVLLAGYQVSAEDLEMNLELIKEALNEEIE
                     QPHREFLLEYLEMGIDVMKHMDTQASFIHASMPYGLEAKTYLQHLLDNKRKEAFEIVES
                     ELNDGATIRDMYRYIFQPVQYEIGRLWQRGQISVGQEHFCTAATQSFISRLYSRWLIGP
                     NKGKKLVAACVGSEQHEIGLRMLTDVFEMEGWDTYYLGANVPNGSIVEAIKRHESDVIA
                     ISVTMTYHLHLAKELIERIRNHAETAHVKVMVGGYPFNIDKELWRTVGADGYAPGAEEA
                     VAIAERLLNHPVSLDNVSTASE"
     gene            complement(15919..16380)
                     /locus_tag="BLQ13_RS22625"
                     /old_locus_tag="SAMN05720606_117166"
     CDS             complement(15919..16380)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689273.1"
                     /locus_tag="BLQ13_RS22625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117166"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_090923939.1"
                     /transl_table=11
                     /translation="MLKTEDNRELSLQLFVVLIRAYNSVTSRSNRDIQSHGLNSTEFGV
                     LDLLYHKGPQALQKIGEKVLMSSGNITYVVDKLQNKNLLFRRPSKEDRRVIYAELTEEG
                     KQLFTQIFPKHHQVIIDILEGLEPSEKVEAIRLLKKLGLAAEGKTDLRI"
     gene            complement(16396..16995)
                     /locus_tag="BLQ13_RS22630"
                     /old_locus_tag="SAMN05720606_117167"
     CDS             complement(16396..16995)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689274.1"
                     /locus_tag="BLQ13_RS22630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117167"
                     /product="GNAT family protein"
                     /protein_id="WP_090923940.1"
                     /transl_table=11
                     /translation="MREFPLRDDELVLRIVEQDDLTELYELIYKDDNPEWKKWDAPYYP
                     LEHEPYERFVQHTLARLEADQKAGRPASLRIIEADGEIVGMISYYIEDPLSMWLEMGII
                     IYKPSRWGRGIGTRSLYMWSGHLFENLPIVRVGLTTWSGNERMMQAATKIGLQIEGRMR
                     KCRLVLGEYYDSIRMGMLREEWEQKLSGETDGNVYN"
     gene            complement(17030..17701)
                     /gene="rpiA"
                     /locus_tag="BLQ13_RS22635"
                     /old_locus_tag="SAMN05720606_117168"
     CDS             complement(17030..17701)
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370599.1"
                     /locus_tag="BLQ13_RS22635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117168"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_090923941.1"
                     /transl_table=11
                     /translation="MNLKQIAAEHAAAFVEDGMKVGLGTGSTAYYAICRIGERVREGLN
                     IQAVATSEASDKLAREWGIPIIPFDQIGRLDLTIDGADEVDPDFNLIKGGGGALLREKI
                     VAANSDKLIIVADGSKAVQKLGKFPLPVEVVPFASEWTFQALENMGCQPEWRMDGQKQY
                     LTDNGNLIADCHLGAIADASELNVQLNMLPGVVDNGLFVKMADVVIIAKEDGSIDELHR
                     P"
     misc_feature    17878..17891
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    17879..17892
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.14"
                     /tool="antismash"
     misc_feature    complement(17944..17961)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.62"
                     /tool="antismash"
     misc_feature    complement(18011..18024)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.41"
                     /tool="antismash"
     gene            18212..19957
                     /locus_tag="BLQ13_RS22640"
                     /old_locus_tag="SAMN05720606_117169"
     CDS             18212..19957
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822412.1"
                     /locus_tag="BLQ13_RS22640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117169"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_090923961.1"
                     /transl_table=11
                     /translation="MSFFSKNLLLSFTNIIIIGVALIASSYYFQRTILVDQLHGQVAQI
                     TKKWAQDINAADVQTAITERSYEGTAQTKLRAYFDEMQKYYPNIAQAYIFGVELGGDNK
                     RLTSLVAMPTNLREAFQSDNVNIGDMYEQPVVVANALKEMLNTDRPTFTTFYSDDFGTW
                     TTIAYPIKDSNGKIFAYFAVDADASAVPKGLNSLLLNGVIILVAFLLLFLIIQYLVVKN
                     TLSPIRHLIKGIDEVSRGNLDVNIPTGKDDLGLVNEKFNVMVRRINDTIVKVQMTSQEV
                     NQSAKELYEVSERNSENADSINNNVTHISTNIRSQEQATRDSARAMSEMATVIQTIASS
                     SASVADEAYEMERRSQQGNTVVRQVSEQMNLITQSVKNTASAIEVLESRSQEIGDILNI
                     ISGISSQTNLLALNASIEAARVGEEGRGFAVVAGEVRKLAEQSEQATSQVGVLIQEIQA
                     GIKQAVQAMEQGTSEVDTGLSVADQTGQLFDEILEAAKKVSHQIQEVSSATQEISAGTE
                     EMTATADDLSASVSKTADSSEKISVSVDEQKASLITLVDSSTRLNDMSEELQELISHFN
                     VSKQQ"
     gene            20001..23705
                     /locus_tag="BLQ13_RS22645"
                     /old_locus_tag="SAMN05720606_117170"
     CDS             20001..23705
                     /NRPS_PKS="Domain: AMP-binding (225-634). E-value:
                     4.5e-105. Score: 343.5. Matches aSDomain:
                     nrpspksdomains_BLQ13_RS22645_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (745-809). E-value: 2.2e-13. Score:
                     42.2. Matches aSDomain: nrpspksdomains_BLQ13_RS22645_PCP.1"
                     /NRPS_PKS="Domain: TD (854-1102). E-value: 2.9e-52. Score:
                     169.3. Matches aSDomain: nrpspksdomains_BLQ13_RS22645_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689277.1"
                     /locus_tag="BLQ13_RS22645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_117170"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_090923942.1"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-115, bitscore:
                     378.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-09, bitscore:
                     31.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 9.7e-51, bitscore:
                     165.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIENQSFSHSVESGLPVLQIPLDYGRRQQTFSYESTHITLKASLS
                     RELNQKFGEQMVYPAFLSAYAALLFRLSAEEELAIGVLAPDQAASYLSLELQGKTTFSE
                     LFEQITRQLQIPYTQQTGGYPETLFMLNSVQLPQAPQVMNWNVRYDQNEMILDLFYDRS
                     LLQESTILRYAEYFQTLLLALLRDDHKAIGAVDILTASDRLLYREMNDTAVLEPAHPTI
                     HGWFEAVAAAYPNSPAITSLSASYTYRELNERANQVARVLISNGLKQGEFVSIFMDRSL
                     DTIISLLGVLKAGGAYVPIDPEHPQERNSYIVEDTASPFVLTTEASFDQAKALFSGIST
                     VRHILSVDGRLAGFAASNPNLDIKPDDLAYVIYTSGSTGRPKGALIAHRGVTNLGSVVQ
                     RDCDIQPGDVLTQFATYSFDASVWDTIGALFYGAELYLLSAEERVSIEEFASAIQRTGT
                     TIITILPTIFFNQLASYLSDEGFHKLEKVRIITVAGEALYGEQVRAFQRKFGNQIDIVN
                     VYGPTECTVATTTHRISEQVPGHVVNIPIGRPIHNYKVYIVNEEHQLCPVGVPGEVYIA
                     TPALAKGYLNLPERTEQSFIDNPFAIGEKIYKSGDIAKMLDTGLLEYVGRSDSQLKIRG
                     HRIEIGEIEDHLARLEQIQDVAVIAKKEADGQNMLVGYFTSKDGSTLSVTDIKATLSEK
                     LPSYFVPKWICQLDEMPIAPTGKINRKAMVSMPHAERHTDQPDRVMPETETESILFHAW
                     KKILQHEEFGVEDSFFSIGGDSLRVIHVLVLLKPHYPQLKIADFFAEKTIRALARRAIL
                     LTEQREPAKRTTTANGIITQLSEHPVELSPQLGYPNILQPEHVLLTGATGYLGSHVLQQ
                     LIVTSSARIYALVRRPSDGTTAMARLSKVMQGYFGKQLADQLEDRVVIVEGNLEEKNLG
                     LAAEQQSLLESRIDRIIHCAADVRHFGEAAQFAKTNVEGTVALLDLIRNKKGASFHHIS
                     TMGIPEDLALSGQWESTLQYDRFPEELHVDNVYSDSKLEAEKVLMTAAEEGVPVSIYRA
                     GNLTCDSRTGRFQTNIDSNAIYRMIKAMLLLGKAPAADWLMDFTPINYASEAIVHLALR
                     QDTAGRVFHICNPEPIRYDALVEAVKRAGYDVETMPFEDYQHWLFDTTIAKEPEALQLA
                     IAQLEGDGAKDSAYAYASPVTTAYVEPAGIFCAKTDERFIHTMLDYAVQIGYFPAAIRP
                     NYGTTTVAD"
     aSDomain        20676..21902
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLQ13_RS22645_AMP-binding.1"
                     /evalue="4.50E-105"
                     /label="BLQ13_RS22645_AMP-binding.1"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="634"
                     /protein_start="225"
                     /score="343.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEAVAAAYPNSPAITSLSASYTYRELNERANQVARVLISNGLKQG
                     EFVSIFMDRSLDTIISLLGVLKAGGAYVPIDPEHPQERNSYIVEDTASPFVLTTEASFD
                     QAKALFSGISTVRHILSVDGRLAGFAASNPNLDIKPDDLAYVIYTSGSTGRPKGALIAH
                     RGVTNLGSVVQRDCDIQPGDVLTQFATYSFDASVWDTIGALFYGAELYLLSAEERVSIE
                     EFASAIQRTGTTIITILPTIFFNQLASYLSDEGFHKLEKVRIITVAGEALYGEQVRAFQ
                     RKFGNQIDIVNVYGPTECTVATTTHRISEQVPGHVVNIPIGRPIHNYKVYIVNEEHQLC
                     PVGVPGEVYIATPALAKGYLNLPERTEQSFIDNPFAIGEKIYKSGDIAKMLDTGLLEYV
                     GRSDSQLKIR"
     aSModule        20676..23306
                     /complete
                     /domains="nrpspksdomains_BLQ13_RS22645_AMP-binding.1"
                     /domains="nrpspksdomains_BLQ13_RS22645_PCP.1"
                     /domains="nrpspksdomains_BLQ13_RS22645_TD.1"
                     /final_module
                     /locus_tags="BLQ13_RS22645"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20862..20903
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLQ13_RS22645_0001"
                     /evalue="5.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="301"
                     /protein_start="287"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LGVLKAGGAYVPID"
     CDS_motif       21105..21164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLQ13_RS22645_0002"
                     /evalue="2.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="388"
                     /protein_start="368"
                     /score="29.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGALIAH"
     CDS_motif       21555..21584
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLQ13_RS22645_0003"
                     /evalue="3.20E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="528"
                     /protein_start="518"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YGPTECTVAT"
     CDS_motif       21696..21785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLQ13_RS22645_0004"
                     /evalue="1.60E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="595"
                     /protein_start="565"
                     /score="39.6"
                     /tool="antismash"
                     /translation="PVGVPGEVYIATPALAKGYLNLPERTEQSF"
     CDS_motif       21867..21932
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLQ13_RS22645_0005"
                     /evalue="1.70E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="644"
                     /protein_start="622"
                     /score="32.9"
                     /tool="antismash"
                     /translation="YVGRSDSQLKIRGHRIEIGEIE"
     aSDomain        22236..22427
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLQ13_RS22645_PCP.1"
                     /evalue="2.20E-13"
                     /label="BLQ13_RS22645_PCP.1"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="809"
                     /protein_start="745"
                     /score="42.2"
                     /tool="antismash"
                     /translation="ESILFHAWKKILQHEEFGVEDSFFSIGGDSLRVIHVLVLLKPHYP
                     QLKIADFFAEKTIRALARR"
     aSDomain        22563..23306
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLQ13_RS22645_TD.1"
                     /evalue="2.90E-52"
                     /label="BLQ13_RS22645_TD.1"
                     /locus_tag="BLQ13_RS22645"
                     /protein_end="1102"
                     /protein_start="854"
                     /score="169.3"
                     /tool="antismash"
                     /translation="VLLTGATGYLGSHVLQQLIVTSSARIYALVRRPSDGTTAMARLSK
                     VMQGYFGKQLADQLEDRVVIVEGNLEEKNLGLAAEQQSLLESRIDRIIHCAADVRHFGE
                     AAQFAKTNVEGTVALLDLIRNKKGASFHHISTMGIPEDLALSGQWESTLQYDRFPEELH
                     VDNVYSDSKLEAEKVLMTAAEEGVPVSIYRAGNLTCDSRTGRFQTNIDSNAIYRMIKAM
                     LLLGKAPAADWLMDFTPINYASEAIV"
     misc_feature    complement(23796..23805)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
ORIGIN
        1 cccgcagcaa cgagcagatc tgcaacagcg cctacgagcg gattcgctgt aatgccggat
       61 aagccatctg agcctccgca tttcaatcca attttcagtt tgctcagtgg cagaggctga
      121 cgtttctctt gctcagcaat ctcaaccagc tcttccatta aacgcaatcc ttcttccaac
      181 tcgtcctcgg tctcttgcgc tttgaggaaa cgtaccttct cccgatactc cggtgcgatg
      241 cactcacgga actgatccac ctggttattc tcacaaccta aaccaatgac cagcacacca
      301 ccagcgtttg gatgctcgac cagtgaggcc agcaactgtt gagtatattt caggtcgtcc
      361 cccagctgtg aacagccgaa aggatgcgga aaatgaaaca caccgtccac ccgactgcca
      421 aattgggact gccccatccg tgcaagagct tcacacacct tgttaatgca tccaacggta
      481 ttgacgatcc agatttcatt gcgaattccc gcttccccgt tcggacgcaa atacccatcg
      541 aacgttcgca aatgttcagg aggcatgtct atcgtcatcg gttgtcctgg ctgatattca
      601 tattcaagca aaccatgcag acctgtcttc aagttatggc tgtgtatcca gctcccctgt
      661 gcaattgctt cctgggcgag gccgatggaa aaaccatatt tcatcacatc tgctccctgt
      721 gcaagatcat gcacagcgat tttgtgccct ttaggtacat catcttgcag tgtgaacgag
      781 tgaccatccg gcagatcaat acgctctccc ttcacataat cgcgaagtgc tatgatgaca
      841 tcgtcctgag gctggatcgc aatccagtcg ttgattgtgc ttgttgtact catttcactt
      901 caccttccag tttactgatt tcatgtacga gtgctgctcg caatccttct ttggcatcca
      961 gattctctcc ccagatcact tcatcggaga gaagcgcagc aaccctcttc tccaattcag
     1021 ccgttccact agtcaagtga tcgtatcctt cccaatgagt agccaaagct gccagtacat
     1081 cagggtcatc tcttagtgga atcgtttctc cgctcaaaag ctgcgctctg tagccctctt
     1141 gcgtctgcaa tgggcgatat aaatagagga atccggcaaa accttgtatt aaccgctcag
     1201 gccagcttcc ctgactctgt tcataggcga gcagggttgg cagtacacgt actttgaatt
     1261 taccggccgt attcagtgca atgtcctgca acttgtgatc aatatatgga tttaagaaac
     1321 gttcaaagac ttcttccgca tatggctcca atcccagctc aggcatatcc atggcaggca
     1381 caatctcttc aagcaccgcc tgcctaatcc aggaactaaa ctgcggatct tccatggttt
     1441 ctcttacatg ttgtttaccg cgaagcaagc ccagagaaga catcagtgta tgtgagccgt
     1501 tcaggatgcg cactttacga agctgatatg gcttcaaatc tttaacccag tgcacattga
     1561 gccctgcttg tttcaatgga aggcgcttgt ccagtgactc ctcgccttgt atcgcccaga
     1621 aatgataagg ctctgccgta ttaatcagtt gatcctcata accccagcgt tccgtgagtg
     1681 catctgcctc ttcctgagtt ggcgcacccg tcacaatacg atctaccaga ttgttcagga
     1741 attgattgtg atgttcgatc caagagcgga agctgtccga gaatccgaaa tcttcactat
     1801 gacggagcac gcattctcgc agaacatcac cattgccctc cagcaattca catggcaggt
     1861 gaatgagtcc tctcgatgga tctccagcaa aacgtacata tctttgatgc aagaaaaccg
     1921 tcaatttacc aggaaaagat tgaacgggct ctcctgggat atagtctgat tggatatatt
     1981 tcaagccgga ttctgtcgta ttcgagatta caaattccag cgatggcaac tccgcaagtt
     2041 ccagaaacgt ctgccactcc tcgtatggat taataaattg agagaagaca gagaccattt
     2101 ccgtacgttc cacacgtttc ccttcagaga gaccacgcgt aatcattgta tataatccat
     2161 cctgatcacg aatctgctcc agtttggcct tgcccccagg ccgaggctgt gtcacggcta
     2221 cagagccgtg aaatttgcct tgccgagcac tctcatgaag catccagtct gcgaatcccc
     2281 gtaaaaaatt accttccccg atctgcaaaa ctttgacggg acgttcaatc atttctttgc
     2341 atttgcgctg actatcattg ccgagcagat gcatcttcaa tcttggccgc tttgtgcttg
     2401 cagacatgga cactcacctc accgattatt tgcgaactca gaatgcgaac agcatatgct
     2461 ggcatccttt tattgtaaac gctttaaatt cattgtatca tcaataaaag gaaattaaat
     2521 tgcttatatt gcgttaaata tactgttttt tgatcagaat tgacatctta tctgagacat
     2581 ttgtctccca aaggagtccc aatggaacat tcaccagttc gcaccaccat tcagaccgaa
     2641 tcgggcatac cgttccgcct tgtctatagt gatacgaaat ctccacaaaa tgaattaccg
     2701 gatcatctgc acgactggca tgaaattatc tatgtctata ggggacaggg aagtattttt
     2761 atcgatgcag gtctcgaaga tatgcaggag ggagatttat ttcttattcc aggcagtacc
     2821 gtgcaccgtg cattgcctga tgcaggtaat ccggttacct cttctgcact gttcttcagt
     2881 ccggggttac tggcttcaac cgccggaggc atgtcctcct ccttgctaca cccatttgaa
     2941 cgctgtcgta aacggcgaat atacaaaagg catctaaacc atgccgagca ggcacaagtg
     3001 tctgccttca ttgatgatat tcatgccgag ttccgttccg atcatcatct gagttctcac
     3061 gccgcactgc tccgattgca gctcttgctt attttccttg aacgtctgga ttcagctacc
     3121 ggtcctgccc ttgctacatc atcactacct actccgtcat ggctgtcctc cattctgtct
     3181 gacattgatc ttaaactgcg caatcgattg actttacctg aacttgcaca acaagctgcc
     3241 gtatctcctg ctcatcttag ccgggcattc aagcgttaca ccggaatgac gctaacggat
     3301 tatgtactcg ctcgtagagt tattatggcg aaggagcatc ttctgaatgg ggatgaaacg
     3361 atggctgctg tcgcagatgc ttgcggattt gatagtttgc ctcattttta cagacagttc
     3421 aagaaactga cgggtacgac accggccgca tatcgcagaa cgatggtaca acatcgctag
     3481 gatgtgaaac ggagatatgc acacacatat tattccaaga gaggatatgg tatgatattc
     3541 aaggtttgcg caacacgatt atattgttac tggagttgaa cctgtgatta ttaaatttct
     3601 tatttttggc ctgctctggc agatcgttgg caatccgttc atcgccattc tgattctgct
     3661 cgtcatcctg tatttcctgg atcgtcgttt tgtcggcgta tttccaagct tcaccaaacc
     3721 ccttaaacgg ttgcgtaaca tttccaggtt gaaacaacag ctagcgctga accctaacga
     3781 agtatcttcc aagctggaac tggcccgatt gctcattgaa cgcaaacgtt acagtgaggc
     3841 acatgccttt ttgcttgaac tggaacgccc ttacgaacag tctgctgagt actgggaagc
     3901 tttgggcaca actgaactgt atctcggcaa aatctcggaa ggcgaacgtc atatcttgca
     3961 tgcacttgag attaacccca gagtcaagta cggacagcct tatctgaatc tggctacagc
     4021 cttcaaggat acggatcgtg acaaagccct tcattatgtg cagcagtttc aggaaatcca
     4081 ttcttcctcc agtgaagcct tttatctgct tggctcggta taccgttcgc tagggcgtaa
     4141 tgaagatgcc aaacaagcat atgatcaatc cctgaatgtg tatcgttcct tgcccaaata
     4201 taaaaaacgt caggaacggc gctgggctgt ccgcagttgg ttccgcaaac gtgctttgta
     4261 gattgaacta ccttcgtata tcagcaagca tcctataaaa gaaagataaa tgtgctggtt
     4321 ctgctctttt gtccgtagca gaaccagcac acttatttat ttgccacgca tgttaattcg
     4381 ttaacaattg acgtaattga ttctcatgcc gccccatcca gtccattcgc tgtttgagtt
     4441 tcacaatttg ctctgtagcc acctctggtt tatccgtccc ttccagcatc cggctgataa
     4501 aatgcataac cacatccaga cttcgcagca aaatcagctg cgggattgct ttcagttcgt
     4561 cagcggtgag ttcaacctct tctcgaaagc cctgcaccag attagcctgc gcctgccaca
     4621 tccattcttc gctcttgtcc atggtcagca tgtcagacat cggaacagcc agttccatga
     4681 ctcgcagatc ccaggtggca aactcaaaat caagaatcgc actcatgttg ccttctgggt
     4741 ctaccagcac attggatgcg ttcacatcac catgcacgat ttgatgcgga agttgctcca
     4801 ttccacgcaa tgctttgaac aaacctggca gttcaaccag caactgctct aactcctcgg
     4861 cacaaacctt cagcgtttcc ggtggcgaag cacacatttc cagtaaacgt tctggtgaac
     4921 acagtggata agcctcgtcg atccggtaat atggcggata taccggctta agttccaatt
     4981 cgagcttggc aagagctgtt gagagatttc ccgctgcccg ccccaaagga cgcaattgct
     5041 cgggggaatc ccataccgga tttacgcctt ccaaataacg aaacagagcc acgactttaa
     5101 aagttcccgt gatatgatct tgtacaagct ggtaagtctg cctattctcc tcattagaat
     5161 ggttactttc cttcgattct tgatccgctg tcttgccgct actactagat aatgaaatga
     5221 ctggtgttgg cgaatgaagt ttaaaatctg tattggacag tgcgataagc acgccatgtt
     5281 caaaagctat tttcgcttga tcattatgtg tttcgtattg tctcataaca tagtctgcat
     5341 cacgggtgtg aagtacaaaa gtagagttat tcatacctcc attgctgcgc ttaccttgcc
     5401 aatccgatct gaagccgtat aaggctaaca cttcagagat taattgtttt tcctttggaa
     5461 gaagagaatt ttgctgtttg ttagacaccg atttgaactc ctctgttacg atgatttgaa
     5521 tgaactcttt catcatatcg gaagttgtaa ggcgggtcta gttttcttca ggcttcaggc
     5581 aaaaggaaca tagcccgttc gattcaactg ctccgcgata atccggtacc ctcttgcgtt
     5641 tggatggact ctgtcccaga aaagcaattc tcgctcacgt ccttcaaact tgtcgtacac
     5701 ctgagcacat gcatagttac ctgaacctgc accattcaga taagaattgt actgtcgcac
     5761 ccagtatgca gcctcggttg attgtggata cgggttgtac aatccaatgg aacgaacaaa
     5821 gtacttctga tcccctttta actgccgaat ttgtcgcata acctgagata catgatgacg
     5881 tgtttcacca agcacttgtg tcattttccc ggcatttgga atacctccgc tagctttaaa
     5941 tgtacggatc agatcgttac caccaatgga taccgtaatc atatctgctt cacgtatcgc
     6001 ttgacgcacc cgaggatgtc cgttaatcat ctgctgaagt tctgccgatg ttagtccgtt
     6061 cacacccaaa ttgtccatag atacaaatgt acgaaggttc atttccgcca tacggcgata
     6121 gattggaaca aatccggttc cgagcaaagc tcctgtacct accgtcaagg aatcccctat
     6181 agctacataa cgatatacca tcccgccgcc cctctctctg ctgatctccc tgatcattca
     6241 tgaactccct atatcctatg aagatcgatt cgacaaagcg cgggatagtg tccttaggca
     6301 aacaccaatc tttgtgtcca tgatgagtat tataaaaaag aaagccccac cacatgatgc
     6361 ggcagagctt cccttccata tgaaatatca acatcaatga gaatcacata ccaacggtat
     6421 gattcgattc ggaagattcc gactgttcct tgttgcggaa cggccaccaa ttcgcccgcc
     6481 cgaacatctt caccattaca ggtacgaaga atggcaggaa taacagggaa tacagaatca
     6541 gaccgctaag cacaacggta gcgatttgca tcatcgagag taccccggac ggatacatcg
     6601 ccgcaaacgt cccgcttaga atgaccgcag cggacaagat gacggttccc atgtttttca
     6661 tcgcgtataa catcgcatcc tgtactctca ttcctttgtt ttcgttaaat cgatccataa
     6721 ggaaaatgct gtaatcaacg ccaagcgcaa tcagcataac gaatccaaag aatggcgtaa
     6781 cccaactgat tccggcataa cccatgatat tcacaaagac cacttccgta agtgccatcg
     6841 atgtgaagta cgcaagcaga agtgaaataa tgagataaat cggcatgatg acggaacgaa
     6901 gcaggattac caagatgata aatgttcctg cgagcatcag cataacggta cgtgtgtagt
     6961 ctttgttcga gatcgactgc aaatcggcaa acgtgctggt tacaccgcct acggcaacat
     7021 cggctttttc aagcgcactg ccctgaattg cacgatgcac tgccgcttcg atatccggca
     7081 cacggtcaat cgcttctgta ccatacggat tctctgcaaa aataacatcc agtgtcatcg
     7141 tcttgcgatc cttggacaga tacgtatcga ataccttttt gaagtccttg ttattcaagg
     7201 cttcttcagg aacgtaccag cctgcgagat cggaatccgg tgaattttgc agttgtgtca
     7261 gataatcctg agcggaatcg agaccgcccg acaccttctt gattccatcc acactttgat
     7321 tcaagccatc tgtcaattgt gttaattgac cactgagatc cgagaagccc ttctggatct
     7381 tctcctgccc tccctgaagc tgacccagac cattctggat agaagggatt tctttgatca
     7441 ctttaccctg accatcggca gcctgtttca atcctgtctc cagttgacct atacctgcta
     7501 caatctgacc cagaccatcg gccaaagcct tctgtccgga tgctgcggaa gcaaaacctt
     7561 cattggcttg attgattcca gccgcagctg aactcagatt cgtctgaatt tgggaaagtc
     7621 cctgcgcaag ctgcgcagtg cctgaaccgg tttgaccaat cgtgcctttg atgcgttgat
     7681 agtcagcatc ttgctgcaac tcagggaaac gctcttccag agcagagaaa gatgctgtaa
     7741 gactcgtcaa tgctgttgag acacctgtca gttgctgctc cagttccttc gttccatcgc
     7801 ccagtgcagc aacacctgct cctgcctgac ggtaggcttg caacaactga tcattcgctt
     7861 tggcaagctg gtctgcactg gttttggctt gttgaagtcc ggctttgaga tcccctgcac
     7921 cagacgatcc gtcccgaatc cctttttcaa tgcgctttag tccgtcgcta agctgcgtaa
     7981 taccggattg cagctggctt gttcccttgg ttagctgacc tgctccgttt gctgcctctt
     8041 taagctgtgg ttcatttttg ctcaattcat tacttgcttt gctaagacca tcgctgattt
     8101 tatccagacc tgtcttgccc tcacccagac catccgatag tgtacctacc tgtttggtta
     8161 cttcaaaatc tttgatctca tcccccgttg gacgtgtcat actacgaaca cccgcaacac
     8221 cgggaacctt ctctacttcg cggctgatct tctctgccac agccatatat ttggcattat
     8281 ccatcgtttc gtcattctga atgacgatct gacccggcag ggattctcct ggcccgaagc
     8341 tatctgaaat aatattaaaa gctttgaccg aatcgtattt gtcaccaatc tcatccagac
     8401 tgttgaatga taatttcccg tcatatgttg acaaaagagg caccgtaact gcggcaacta
     8461 tcaacagagc tgcccacgga cgtttaagtg agaatttacc tgctgcaccg tagattttgc
     8521 tctcggcatg ttcgagcgat cctttggatg gccagaataa ctttctgccc agtacagcca
     8581 taaagaacgg cacaatcgtc acgagtgcca gcatcatcac ggcaatccct acagcgacag
     8641 cgaccgcaga acggtacaac ataaactggg cgaaaccgat ggccacgaat ccaaccagca
     8701 ctgccagagc agagaaaaat actgttttac ctgcggtgcg atatgtagct ataatggcat
     8761 cccatgtgtt ctcatggtgc gcaagttctt ccttgaaccg gctgatcaat agaatgcagt
     8821 agtctgtacc gatcccgaac ataactgcaa ccataaagat ctgtgtgaac gtagagagcg
     8881 ggaagttaac cccatcgacc aggaacgcaa caatctgttg ggatacgata tagctgattc
     8941 ccaccgtcag cagcggtaca aatggtgcca cgaacgagcg gaacacgagg aacagaataa
     9001 gcaaaataaa gacaaccgta atgtattccg atttcttgag tccttcctga gaactctcaa
     9061 tcgtatcttc atcaattaac cctttacctg taatataatg ctccacattt actgattcca
     9121 gcgcatcatt cagatcgttc cgcatttcct ttaccgtgcg gtcacccatc tcaatggaga
     9181 gtgaagtcag aatggtttta ccgtccttcg agatcatttt gtctgacagt tctggctgtg
     9241 agaatggttc cagaacagac aaaatgccga gtttttgttt atcggcctca agcagtttaa
     9301 ccgccttttc tgcctcttgt ttacctgttg tgccaagacc atctggatta taaaacacca
     9361 gtgcaataga agttcctttt tgttctccat tttgggctgc ggcttcattc aaaattgccg
     9421 ctgcgtttgt ggaagagtac ccctccggca cggaaaactg tcctttttca cgaattaatt
     9481 cactcatgtt tggcgcggta aacatcaata cagctgcggc gacaatccac agccccatga
     9541 tccaccagcg tccttttaat atcgctctca ttacttctcc agcccttctt cttgtgttag
     9601 taacgctgca agcttctcaa aagattcaat aaagttctgg accgcttctg gtgtaaaatg
     9661 tttcaagtaa ggttcaagaa ccttctgaat ttccagctca gtctccttgt aaatctgaag
     9721 accagcctcg gtcagagtca gatagataac acgacgatca cgttcatccc ctgcacgatg
     9781 caccagattc cggtcagcca gcttgttgac cagagccgta atgctactct tgcccacaca
     9841 caggagctcc gcaagatccg acggggtgca ggcaggcttt tcatgtatga ggcgcagtgc
     9901 acaaaactga tccgttgtga ccgtttgccc taccttttcc cgtatctggg tatcaaatcg
     9961 cttgttaacc aggaaagatg catccagata acgattcacc aaacttttgg catctgggat
    10021 gttcatatat ttttctcctt tcaaaactag ttcacataac gaactattca tcagtaaaac
    10081 tattctataa tgaaactatg ttgagaagca atactttttt cctactcctt aaacaaaaaa
    10141 acaggacatc tggctcagca cttttgccaa gccaaatatc ctatctgatt taatcgtata
    10201 tgattatacg caaaacgttt taaagtacat cccttgctag gcttcctgct catcgtcctc
    10261 tttctcaagc acacagcgga atctctccac gcctggatac agttcaccga gactatagac
    10321 gacaaatccc gtgtttcggt aaaactccac cgcttcctgg tccgtttccg caatcaaagt
    10381 atctggattg tactctgcaa gaagctgtga aatcatgccc cgcccgtaat ttttgaaacg
    10441 gttctcgggc agaactgcaa tgtggcgaat ggtaatttcg ttcgctcccg tatgttcata
    10501 gccaattagg ccaaccaact gtccttcatc ctcatatcct gtcagaaaca ggttactctg
    10561 tgtcacatac tgctgtaccg cctgattgac ctgatcaggg tcaggaaaga cagcgtaaga
    10621 gagcagctcc tggacttccg gctcctgcaa tcgtggcttc aaatttttca acaaaacaat
    10681 tcctccaata taagtactta gtctttctgc acagcaaacc gaagcaactc gcaacgaaac
    10741 tctgtcggtt catcatactt ctcttcttgg atcgtctggg ttacatgctc ctgaaacaaa
    10801 atgttccagc cctcgtaggc ctgttccagt aaagccatga cttcggatgt cggcaggttc
    10861 aattcaatca atggctcaat ctgacggcct gtctggattt ctttttcttc cacactggta
    10921 ctcatcataa tacaatggat acctccgagc cgggttccct cttttaatcg ttccactgtt
    10981 tcaagaaaag cctctttgct agatgtgtgt tccagacagg aacaggccgc aataaagtca
    11041 aatgctttcg gttgaatccg gtaatgctca acatctgctt tttcggcctg aacgatgtga
    11101 tccacctcat actgtttcgc atacttgcga agtccgtcta ccgcttcatc caacagatcc
    11161 acgccaataa cctcgctgtt tgtatctgcc agacgttgtg caatcggaat cgtatgtctg
    11221 cccacaccac atcccaggtc aagtacacgt aattcctgtt tatgaacaag caaacgttcc
    11281 aacatctcca tcaccatagg catgggtctg gacatccatg ttccgtcttc aaacaattca
    11341 ttgtttttat aaaagttaga atgatatccc gcttcggctt gacgagcagc ctcaaattgt
    11401 tcttcccgca tttagttacc tcctgcaatg gatttagacc tttacagtaa cgttcaccta
    11461 aaaacgaaga aaagaatcat ataaattact atcataatta aactggccgt gacaagtatt
    11521 ttccccgcat cccgtttact ggcatagtca ttaaacaaca gtattccacc aatggtcatc
    11581 gcaatgggcg caaaaaatat cgtcatgatc acgagcagca ccatagaata acgatccaat
    11641 gtcgattctt catactccga catatatggc tgatctggct tggccgtttt ggtcgttacc
    11701 atattgccgc acgacttaca tttgaattca tcttctccca taggttgatg acaatacgag
    11761 cattctcttg aaaaacgtgg catatctatc tccctccatc ggtgaaccgg tctcaaagtg
    11821 gcatatgttt ctgcaaaaaa gctcccagca ccgctttata tttctcgcga tcaacctgaa
    11881 aggccgttcc gtgacctgca cgaggaatcg tcagcagttc cttctctgac ttacacactt
    11941 cgtacaagcg atacaccatt tccgttggta caaacaggtc cgcctcacca tggatgaaga
    12001 gcaccggtac gttaactttg gcgagttgct tcagtgcaga tgcttcttta aatgagtatc
    12061 cggccttcca tcttgtaatc aagctggtca ccggaatgaa cggaaaaggc ggtagcttgt
    12121 acaactgttt caattggaat gtcagttctt cctcaaccga tgtataggca cagtccgata
    12181 caatggctct gacctgatca ggcagctctt ccccgcctgt catcagcaca gtcgcacctc
    12241 ccatcgatat gccatgcaga acaatatctg tatttagtcc tacatgtccc agcacccatc
    12301 cgatccactg aacataatct ttccgatcta accagccaaa tccgatgacc tctccttcac
    12361 tctgaccatg tccgcgatca tccggcatta atacgtgata acccagggtt tcagcgtaaa
    12421 atcgggcgaa gcccgccatt tctctgcctt tccccgagta gccatgagcc agaataactg
    12481 tctttgcaga cttgttcttt gaaggaagcc agatgccaga gagtctcaat ccatcttgag
    12541 actggatggt caccgtcttg gtatcctgag catcaagcca ttgtaaatca ccaacagtac
    12601 tgatcagttc atcttccact tccgttttaa gattcggatt atccgccaaa aatgttttcg
    12661 gcgtacgccg aatcgctgtc ttgaagaaat aaagtcctcc aacccacagc agagctatga
    12721 tgatgatgat gagagccgcc agcccgtaaa atatcatgta aaaaatcctc catttcagtc
    12781 tatgagttaa agcgactcca tatttaaatc aattataatg ccgtcataac ctagcatgct
    12841 tcaactttta ttagcctgct gcagcgctcc gcaagcagcc tggtacgcgg gaagtagctt
    12901 atcaagcagt ggttctgctt gatgggttag ttcctgtttc gcgtatttct caatctggct
    12961 gaacaacgtt gagagataac taattccgag gcttagactt cctgatttca agtcatgggc
    13021 agtctcggcc gccgccttat gatcggctga aacaacatgt ctgcgcaagt cctcaatttt
    13081 acctggcgtc tccgcccggt acatctccag caacatactg agcaacgttt ggctcccatc
    13141 cgtatttaat tcagcaatct cacggacaac gtccatattc agaatctgta caggtttcga
    13201 tgccgagtgc cacttccgaa tggtcgtatc gagcacctct aaggtaaatg gcttaccgat
    13261 aaagtcattc attccagcct cataacactt gtccttctca ctttgcatta cattgcctgt
    13321 cattgcaata atcggcgtag ctggacgcat ctcatcctgc tctattgcac ggatctggcg
    13381 tgcagcttca atcccgtcca gaacgggcat catactatcc atcaaaatca gactatatgt
    13441 tttatcacga aacgcattca cagcctcttc cccactggat acacattcga gttcagtaaa
    13501 acccagcttt ttgagttgca gttgaacaag ctgacggtta ataacattat catcagccag
    13561 tagaatgggc aaggtgcgag catcttgctc aggtgcatcc ttagagctgt tcttcgtcgc
    13621 atcgccaaca tcgtttttgg catcatttgt aagatccgaa gtttcgtcag ctaccgttaa
    13681 ctgggcactc tctttgcttt ccaccatgtg cagcccaagt tcaagctcaa accagaaaat
    13741 ggaaccttcc ccttccttac tcctgattcc gatctctccg ttcattaatt gaacaagtga
    13801 cttgcagatc gataaaccaa gacctgtacc ctcatactct ttcgaacgtc cctgctctgt
    13861 ctgcatatag ggttcgaaca aacttatctg atcttcttct gaaataccaa ttcccgtatc
    13921 atgcacctcg aagcgtacaa gctgagtgcg tgcctgctgc cttacaagct taacttccac
    13981 cttaacagat ccatcggtag tgaatttgtt tgcgttctga atcaggttaa tcagtatttg
    14041 tgtaattcgg gtagaatctc cttcaagcac ggcggcgact tctgggtcac aatccatgat
    14101 catgcgattt cttttcttat caatctgggg cttaagcaga cgcaagatgt aatccataat
    14161 ctcttggagc tttacctctc cttgttcaag acgcaattga cctgcttcaa gcttggaaaa
    14221 atccagaaga tcctgaatta atttaagcaa aagcttggct gcctcctgga taacaatgac
    14281 tgaatccttc tgctcctccg ataaaggcga gtacgttaac aactcagcca tccccaatat
    14341 tccgtttaac ggtgtccgaa agtcgtggct gatgaccgcc ataaaagcac ttttggattc
    14401 gtcagatgct acagccttct gacgtgctga ctcaagaccc gcattgttct tggaaagttg
    14461 ccgctgaagc gtcacaagct cattattcat atcagaaaat gctgaaagag tgcgttcctc
    14521 ttgctccttg cttcgaatca gttggtcaga taactgctca atcgttttac gcagtctctg
    14581 tatctcttca ttgtcactcg gcatcccttc atccctttcc tattcacttg ccgtacttac
    14641 attgtcaagc gacaccggat gattaagcag acgctcagcg atagcaacag cctcttctgc
    14701 tccaggtgca taaccatcag caccgactgt tcgccataat tctttgtcta tattaaacgg
    14761 ataaccgcca accatcactt tgacatgagc cgtttctgca tggttgcgaa tacgttcaat
    14821 caactcttta gccagatgaa gatgataagt catcgtcacc gaaatcgcta ttacatcact
    14881 ctcatgtcgc ttgattgctt ccacaatgct tccatttgga acattggctc caagataata
    14941 cgtatcccag ccttccattt cgaatacatc tgtaagcatg cgtagcccaa tctcgtgctg
    15001 ttcactcccc acacaggctg caaccagttt ttttccctta ttcggtccaa tcagccatct
    15061 ggagtacaaa cgagaaataa atgattgtgt tgctgctgtg caaaagtgtt cctgaccaac
    15121 actaatctgt ccccgttgcc ataaccggcc gatctcgtat tgaacaggct gaaaaatgta
    15181 gcgatacata tcgcggatcg ttgcaccatc attcagttct gactctacaa tttcgaaagc
    15241 ttccttgcgt ttattatcta gcaaatgttg caaatacgtc tttgcttcga gcccgtaggg
    15301 catggatgca tgaataaagc tggcctgggt atccatatgc ttcattacat cgatccccat
    15361 ctccagatat tccaacagaa actcacggtg aggttgttcg atttcttcat ttaacgcctc
    15421 tttaatcaac tcaagattca tttccagatc ttccgcagat acctgatagc cggcaagcag
    15481 aacttttaac cacgatatat agtgagtgaa caaaccggga cttttcacaa gcacactttc
    15541 tgccagatag ctcagactgt actgtgagtc ctgcttggtt cttatttttc caattggacc
    15601 gaaacgttcc attaagtcgg gctgcaaccg atactgcatt tcggttattt tctcagccaa
    15661 gatttctgca tcttgaagta aacgttctcc ggcctcccga tgactcatcg acgcattcct
    15721 cctttgccct gcatcctgtg ccgcataaat ctatatcatg tatatcattc cgtttaggaa
    15781 actctactaa tctagtatac atgaagagtt ctatatcatt tcgatgatat aaaacaatct
    15841 tcctatatta tgtagatata cgcaagccat atagccagta tccgaggtat gttgaagaca
    15901 caaaaaaacg gatccacgtt atatacgcag gtccgttttg ccttctgcag caagccctag
    15961 tttcttcagt aggcgtatcg cctcaacttt ttcggatggt tcaagcccct ccagaatgtc
    16021 aataatgact tgatgatgct ttggaaatat ttgcgtgaat aactgtttcc cttcttccgt
    16081 caattccgca tatataaccc ggcgatcctc cttggaggga cgccgaaaaa gcaaattctt
    16141 gttttgtaac ttgtcaacaa catacgtaat attgccacta gacatcaata ctttttcacc
    16201 gatcttttgc aaagcctgtg gtcctttatg atataacaag tcaagtactc cgaattctgt
    16261 ggaattgagt ccatggcttt ggatgtcccg attggaacgt gatgtcactg aattgtatgc
    16321 gcgaataaga accacaaaca attgcaatga caactcccgg ttatcctccg ttttcagcat
    16381 ttctataatc ctccatcagt tatatacatt tccgtccgtt tcaccggata acttctgctc
    16441 ccactcctcg cggagcatgc ccatccgaat tgaatcataa tactctccaa gaacgagccg
    16501 gcacttccgc atccgcccct cgatttgcag tccgatcttt gttgcagcct gcatcattcg
    16561 ctcattacca gaccacgtag tcagtccaac cctcacgatg ggcagatttt caaataaatg
    16621 acctgaccac atataaagtg aacgtgtacc gatccccctc ccccatcgag aaggtttgta
    16681 gatgataatt cccatctcaa gccacatcga taacggatct tcaatataat aactgatcat
    16741 tccaacgatt tctccgtctg cctcaatgat tcgaagggat gctggccgcc ctgctttttg
    16801 atctgcttcc aatcgtgcaa gtgtatgctg cacaaaacgc tcgtatggct catgctccag
    16861 cggataataa ggtgcatccc actttttcca ttcgggattg tcatccttat aaatcagctc
    16921 atatagttca gtaagatcat cttgctccac gattcgaaga acaagctcat catctctaag
    16981 gggaaattct ctcattctag atcatgacac caactttccg tcaaattcgt tacggacggt
    17041 gaagttcgtc gatactgccg tcttctttgg caatgatcac aacgtccgcc atcttcacaa
    17101 atagtccatt atccacgaca cctggtaaca tattcagttg tacgttaagt tcggaagcat
    17161 cggcaatggc ccccagatgg cagtctgcaa tcagatttcc gttatccgta aggtattgtt
    17221 tttgcccatc catccgccac tctggctgac atcccatgtt ctcaagcgcc tgaaaagtcc
    17281 attccgatgc aaagggtaca acctcgaccg gtaaagggaa tttccccagt ttttgtacag
    17341 ccttgctacc gtcagcaaca atgatcagct tatcgctatt tgctgccact attttttcac
    17401 gcaatagagc tccgccaccg cctttgatca ggttaaaatc cggatccact tcatccgccc
    17461 cgtcaatcgt cagatctagt cgtccaatct ggtcaaaagg aataatcgga ataccccatt
    17521 ctcttgccag cttgtctgaa gcctctgagg tagctactgc ctgaatgttc agaccttccc
    17581 gaacccgctc cccaattcga catatcgcat aatatgcggt tgagcctgtg cccaaaccaa
    17641 ctttcattcc atcttcaacg aacgctgccg catgttctgc tgcaatctgc ttcagattca
    17701 ttatttaacc cccgcctgct cattaatttg tataaaccat tatgtagtta ttatagataa
    17761 aacctcatcc gatgtatatc caagcttcct gaacagatta agatcggctt tctgatgata
    17821 aatggtgtaa tttttcccgc tatgttatag aatacagaat gaaactaaaa aatggcaatt
    17881 tttaaaaata aacagtacta attacctata aaaagaaaga tatgtccata aatacgtaaa
    17941 atattaaaaa agttttaaca aaactattca aattaacgac attttacacg acataataga
    18001 tatagatgtg ttttaataat tagacacact ggttccaaaa ggtacataag tcttgcatag
    18061 tgactaagaa aaccaagacc attgtcgcac tttcccttta gaaggagatg acagaatgaa
    18121 gtaacttttt gctccaaaag cgcatcttac agatttttaa tttacagaag atcaggagtg
    18181 gagtttagtg aaatcattga gttggaaaaa catgtcgttt ttctctaaga acctattgct
    18241 ctcatttacc aacatcatca ttattggcgt ggctctgatt gcaagcagtt attacttcca
    18301 aagaacgatt ctggttgatc agctgcatgg acaagtagcg cagattacga aaaagtgggc
    18361 tcaagatatc aatgcggcag atgtacaaac tgcaattaca gagcgcagct acgaaggtac
    18421 tgctcagacg aaactaagag cttatttcga cgaaatgcaa aaatattatc ctaacattgc
    18481 acaagcctat atcttcggtg tggagcttgg cggcgacaac aaacggttaa cttcccttgt
    18541 tgcgatgcca acaaacctga gagaggcttt tcagagcgac aatgtaaata ttggcgatat
    18601 gtacgaacaa cctgtcgttg tagccaatgc tctgaaagag atgctaaata ccgatcgtcc
    18661 aacgttcacc accttttatt ccgatgactt cggaacctgg acgaccattg cttatccgat
    18721 caaagacagc aacggcaaaa tttttgcata cttcgctgtg gatgcggatg ccagcgcagt
    18781 tccaaaaggt ctgaattcct tgttattaaa tggagttatt attctggtag cgttcttgct
    18841 tctgttcctc attattcaat atcttgtcgt gaaaaatacc ctctctccga ttcgtcatct
    18901 gatcaaaggc atcgatgaag tcagcagagg taatctggat gtcaacatcc cgacaggcaa
    18961 agacgatctg ggacttgtaa acgaaaaatt caatgtcatg gtacgccgta tcaacgacac
    19021 gatcgttaaa gtgcaaatga cctcccagga agtaaaccag tctgcgaagg aactctatga
    19081 agtctctgag cgcaacagtg aaaatgcaga ctccattaac aataacgtta ctcatattag
    19141 tacaaacatc cgttcacaag aacaggctac ccgtgatagt gcacgcgcaa tgtccgagat
    19201 ggctaccgta atccagacca ttgcgagtag ttccgcaagt gttgcggacg aagcctatga
    19261 gatggagcgt cgttcacaac aaggtaatac tgtagttcgt caggtatccg agcaaatgaa
    19321 cctgattacg caatctgtga aaaatacagc ttcagcgatc gaagtgctgg agagccgttc
    19381 acaggaaatc ggtgatattc tgaacataat ctcggggatc tcaagccaaa ctaatctgct
    19441 tgctcttaat gcatccattg aagcggctcg tgtaggtgaa gaaggaagag gttttgcggt
    19501 agttgctggc gaagtacgta agctcgccga acagtccgaa caggcaacca gtcaggttgg
    19561 cgtattgatt caagagattc aggccggtat taaacaagct gtacaagcca tggaacaagg
    19621 tacttctgaa gtagatacag gtctctccgt agcggatcaa accggtcaat tatttgatga
    19681 aatcctggaa gcagcgaaaa aggtatccca ccaaatccag gaagtttcaa gtgcaaccca
    19741 ggaaatttca gcaggcacag aagagatgac cgcaacagcg gatgacttgt ctgcaagtgt
    19801 aagcaagaca gctgatagca gtgaaaagat ctctgtatct gtagacgagc aaaaggcttc
    19861 tctgattacg ctggtagact cctccactcg actcaatgat atgtctgaag agctacagga
    19921 attgatttct catttcaatg taagcaagca acaataaaaa aataaataac actcggtttc
    19981 aaccaaggag gatacctgaa gtgattgaaa accaatcttt ctcccactcc gtggaatctg
    20041 gcttgcctgt tcttcagatt ccattggatt atggacgtcg ccagcaaaca ttctcttatg
    20101 agtctactca tattacattg aaagcgtcat tgagtcgtga acttaatcag aagtttgggg
    20161 aacagatggt gtaccctgca ttcctttcag cttatgcagc cttgttattc cgattgtctg
    20221 ctgaagagga gctcgcgatt ggagtacttg ctccggatca ggcagcttct tatctttcat
    20281 tagagcttca gggaaagaca acgttcagtg aattattcga acagattaca cggcaacttc
    20341 agattcctta tacacaacaa accggaggat atcctgagac actgtttatg ctaaacagtg
    20401 tccagttgcc tcaggcacct caggtgatga attggaacgt tcgttatgat cagaacgaga
    20461 tgattctcga tctgttttat gaccgttcgt tgttacaaga atcaacgata ttgcgatatg
    20521 cggagtattt tcaaacacta cttctcgctc tcttgcgtga tgatcacaaa gcaatcggtg
    20581 cagtagacat tctgactgct tcagaccgat tgctctatcg ggaaatgaat gacaccgcgg
    20641 tacttgagcc agcgcatccg accatccatg gctggtttga agccgtcgct gcggcatacc
    20701 cgaattctcc ggcgattacc tcactttcag cgagttatac gtaccgggaa ttaaatgaac
    20761 gcgcgaatca ggttgctcgc gtgttaatat ccaacggatt aaagcaaggt gaatttgtca
    20821 gtatttttat ggatcgcagc ctggatacga ttatctcgtt gctcggtgtt cttaaagcag
    20881 gcggtgccta cgtgccgatt gatcccgaac atccgcaaga acggaacagt tacattgtcg
    20941 aagatacagc ttctccgttt gtactgacaa cagaagcttc gttcgatcaa gctaaagcat
    21001 tgttttccgg catttctacg gtacgtcaca ttctttccgt ggacggacga cttgcaggat
    21061 ttgctgccag caatcccaac ctggatatca aacctgatga tctcgcttac gtcatctata
    21121 cttcaggctc tactggcaga ccgaaaggcg cactgatcgc tcaccggggt gtcaccaatc
    21181 tgggcagtgt tgtacagcgt gactgcgaca ttcaacctgg cgatgtatta acgcagtttg
    21241 ccacatacag cttcgatgca tccgtatggg atacgatcgg tgctctgttc tatggagccg
    21301 agctttatct gttatcggcg gaagaacgag tatctattga agagtttgca agtgcaatcc
    21361 aaagaacagg gacgaccatt attacgatat tgccaacgat tttctttaat caactggcct
    21421 cttatctgtc agatgaaggc tttcataaac tggaaaaagt acgtatcatc accgtagctg
    21481 gggaagctct ctacggggag caggttcggg ctttccaacg caaatttggc aatcagattg
    21541 acatcgttaa tgtatatggg ccaacagaat gcaccgtggc caccacgaca caccggatta
    21601 gtgaacaggt cccgggacac gttgttaata ttccgattgg cagacctatt cataattaca
    21661 aagtatacat tgtcaacgaa gagcaccagc tatgccctgt aggcgtacca ggcgaagtgt
    21721 atatcgcaac tcctgcactt gccaaagggt acttgaacct gccggagcgc acagagcaat
    21781 cctttattga taatccgttt gcgattggtg agaaaatcta caagtccggg gatattgcca
    21841 aaatgttgga taccggatta ctggaatatg tgggacgcag cgactctcag ctgaaaattc
    21901 ggggtcaccg aatcgaaatc ggtgaaatcg aagatcatct cgccagactg gaacagatcc
    21961 aggatgttgc cgttattgca aagaaggaag cggacggcca aaacatgctc gtgggttact
    22021 ttacgtccaa agatggaagc accctttccg taacggatat caaagcaaca ctttcagaga
    22081 aacttccatc gtacttcgta cccaaatgga tttgccagct ggatgagatg cctattgcac
    22141 caacagggaa aatcaaccgc aaggccatgg tgtccatgcc acatgctgaa cgtcataccg
    22201 atcagccaga ccgcgtgatg cctgagacag aaacggaatc tatactcttt catgcttgga
    22261 agaagatttt acaacacgaa gaatttggtg tcgaagacag tttcttcagt attggtggcg
    22321 actccctgcg agtcatccat gtactggttc ttctgaaacc acattatccg caactgaaaa
    22381 tcgctgattt ctttgcagaa aaaacaattc gtgctcttgc tcgccgagcc atacttttaa
    22441 cggagcaacg tgaaccagcg aaacggacaa ccactgcaaa tggcatcatc acgcagcttt
    22501 ccgaacatcc ggtggaactg tctccacagc ttggatatcc gaacattctt cagcctgagc
    22561 atgtgctatt gacgggtgcg accggttatc tgggctcaca tgtactacaa cagttaattg
    22621 tgacgtcttc ggcacggatc tacgcgcttg ttcgtcgccc aagcgatggc acgacagcaa
    22681 tggcacgttt aagcaaagtg atgcagggtt atttcggcaa acaacttgct gaccagcttg
    22741 aagatcgtgt tgtgattgtt gaggggaatt tggaggaaaa gaacctgggt cttgccgctg
    22801 agcaacaatc gttgcttgaa tcaaggattg accgtatcat tcactgcgcg gctgatgttc
    22861 gtcatttcgg ggaggcggcg cagttcgcta aaaccaatgt cgagggcaca gttgctctgt
    22921 tagacctgat acgtaacaaa aaaggggctt cgttccatca catatcaacg atgggcatac
    22981 ccgaagatct ggccctcagt ggacaatggg aatcgacatt gcaatatgac cgtttcccgg
    23041 aagaattaca tgtggacaat gtttactccg acagtaagct cgaagcggag aaagtactca
    23101 tgaccgccgc agaagaaggc gtgccagtca gtatctaccg tgcaggcaac ctgacatgtg
    23161 attctcgtac gggtcgtttt cagaccaata tcgatagcaa tgcgatctac cgcatgatca
    23221 aggccatgtt attgctgggc aaagcccctg ccgcggactg gctgatggac tttaccccga
    23281 tcaattatgc cagcgaagca atcgtacatc tggccttacg tcaggatacg gctggacgtg
    23341 tgttccacat ctgtaatccg gagccgatcc ggtatgatgc cttagtagaa gccgtgaagc
    23401 gtgcaggtta cgatgtcgaa acgatgccgt ttgaagacta tcaacactgg ctgtttgata
    23461 caaccattgc caaagagccg gaagctctgc aacttgcgat cgctcagttg gaaggtgacg
    23521 gagcaaagga ttcagcatat gcctatgcat cgccggtaac aacggcttac gttgaaccag
    23581 ctggaatctt ctgcgccaag accgatgagc gtttcattca taccatgctg gactatgcag
    23641 ttcagatcgg ttatttcccc gcagcgatcc gtccgaatta cggtacaaca acggttgcag
    23701 attaaacgat atgttggata acaatatcaa tagaaattaa taaagcaaaa gccactttat
    23761 cgtgttatga actgctcccc gtcaagtaga cactttaaaa aaacaaaaat gattcgtttg
    23821 gataccttag ctcggatgac gtgctgaggt atctttgtta tg
//
