LOCUS       NZ_FMVM01000006        23345 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Paenibacillus polysaccharolyticus strain BL9, whole genome shotgun
            sequence.
ACCESSION   NZ_FMVM01000006
VERSION     NZ_FMVM01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polysaccharolyticus
  ORGANISM  Paenibacillus polysaccharolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900102085.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 18:13:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,652
            CDSs (total)                      :: 5,587
            Genes (coding)                    :: 5,563
            CDSs (with protein)               :: 5,563
            Genes (RNA)                       :: 65
            rRNAs                             :: 6, 5, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 3 (16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 6 of 24
            Pseudo Genes (incomplete)         :: 17 of 24
            Pseudo Genes (internal stop)      :: 4 of 24
            Pseudo Genes (multiple problems)  :: 3 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:28:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 207895
            Orig. end                         :: 231240
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMVM01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23345
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23345
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23345
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13345](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13345)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(387..575)
                     /locus_tag="BLQ13_RS10315"
                     /old_locus_tag="SAMN05720606_106186"
     CDS             complement(387..575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691019.1"
                     /locus_tag="BLQ13_RS10315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106186"
                     /product="hypothetical protein"
                     /protein_id="WP_090918827.1"
                     /transl_table=11
                     /translation="MSQEVLERRSELLKKNIHQMLVQDNQHGISRQDNMFLQQMIKELH
                     QTSHELNTMSNEESSQD"
     misc_feature    complement(692..705)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            895..1725
                     /locus_tag="BLQ13_RS10320"
                     /old_locus_tag="SAMN05720606_106187"
     CDS             895..1725
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691020.1"
                     /locus_tag="BLQ13_RS10320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106187"
                     /product="histidine kinase"
                     /protein_id="WP_090918829.1"
                     /transl_table=11
                     /translation="MSYKQIKWMILLIPTITVGLWEYIRHQFLMPYLSMDAGNWLTPVI
                     VYLVSVTLLSRLFLMLEGARAALEQERASKTALEARDQLARELHDGISQSLFLLSVKTD
                     KAGRSLAGTSHEQDLREIQKTVHEVNTYVRQAIAQLRYVPSPVADPEAVALQAQVESIV
                     SDTVPEADIEWNLTEVSFSAKEQVELLACIREALLNVRKHAHATKVEVYTKGNASNWSV
                     HIRDNGIGIQGDPMLFKDRYGLRITKERAEQMGWTFQLDSASGNTQMIIGKGQT"
     gene            1725..2381
                     /locus_tag="BLQ13_RS10325"
                     /old_locus_tag="SAMN05720606_106188"
     CDS             1725..2381
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691021.1"
                     /locus_tag="BLQ13_RS10325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106188"
                     /product="response regulator transcription factor"
                     /protein_id="WP_090918831.1"
                     /transl_table=11
                     /translation="MELVRVLVVDDHAHAREAICTILSEDSLFEVIGTAKNGQEAIELT
                     EHWMPDLILMDVQMPDMDGLEATRQIKLRFPYVMIVMVTVSDDVTYLFEALKQGAQGYL
                     RKNLSPSTWLEYLRAIVSDDAPLSKELAYRILQEFPAPRSEDVQENPLTARELEILQWV
                     SAGYTNREIAEQLGISDQTVKNHLKNILQKLQLENRVQLTRYALESGLAGRKPRK"
     gene            2635..4350
                     /locus_tag="BLQ13_RS10330"
                     /old_locus_tag="SAMN05720606_106189"
     CDS             2635..4350
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016149.4"
                     /locus_tag="BLQ13_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106189"
                     /product="copper resistance protein CopC"
                     /protein_id="WP_090918833.1"
                     /transl_table=11
                     /translation="MRVRSLTLHWSKRHWALLTSLLLVFCLVMPQWASAHAYIVKASPE
                     ENELLVTAPQRLTLEFNESLQTAFYDIKITGPDGNQAGDGNVQIDSERPHIMETGLKPG
                     LADGTYLVNWKAVSADGHPISGAYVFHIGEPTGAPAGLKDLASGSGATGGPLKWIVSFT
                     DWIQYLGLSVILGTLAFLLLRIAPASLLREPMEAPGSYKLFWISYAASSFAALISLPLN
                     TLYESGVNIGEFSWALLGSALKLTSFGQIWMLQMLIAMLLAVTLLSGYDLDRSLRVRIW
                     SSYGSLVLVLGWLLTHAMTGHPAAAEQRVLAVAMDFVHLAAAAFWIGALTAMAVCLPAL
                     TNRLPAKLRGEVYWAAIRRFTVWGIGAVAVLVATGIYGSLVILPAPLLNSLFTTAYGLV
                     LIGKILLLIVMIGFALIHAKRARAATGKQLSGSLKAELVTGAIILALAAVLTHLSPGQP
                     APVGPYKGTQTTDDGSVITLQVSPNVVGENQFEVSIKRADGSIVKDLEQVTLSLIHLDM
                     DMGIYEITIPKNDTGVYKAEDYISMPGKWSIQVHALTRSLDALDAEFKIEAAKP"
     misc_feature    4417..4431
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 24.36"
                     /tool="antismash"
     gene            4425..5207
                     /locus_tag="BLQ13_RS10335"
                     /old_locus_tag="SAMN05720606_106190"
     CDS             4425..5207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017814000.1"
                     /locus_tag="BLQ13_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106190"
                     /product="YcnI family protein"
                     /protein_id="WP_244159276.1"
                     /transl_table=11
                     /translation="MKKTSWVSKLTSAMATGAAAFLLFSGLASAHVTVNPSVAQTSAWQ
                     TYTIKIPSEKELPTTKITLKIPEGVAFKQYQPLSGWKITTEKNDSKEVTSITWEIDGDN
                     QGILAGQFQQFNFVAQNPKTETEVAWDAFQYYSDGSIVEWTGQPGANSPHSITTISEDP
                     AAAGNAATGGSSNGHDSAGTAGTATGDKASDTATDGKKGNDDTTLGDALSDTVTGQPNN
                     TDSDAGTLKLQQATLIVSILALIMSFLGIALATRRKKR"
     gene            complement(5395..5667)
                     /locus_tag="BLQ13_RS10340"
                     /old_locus_tag="SAMN05720606_106191"
     CDS             complement(5395..5667)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691024.1"
                     /locus_tag="BLQ13_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106191"
                     /product="hypothetical protein"
                     /protein_id="WP_090918837.1"
                     /transl_table=11
                     /translation="MSGQLLVELNDLRIAEKELSQLLVRMQADEQEARALYSRLNDWKG
                     QSADHTRQQIEEFFAGLAKRIQSIEMQKKSLIQYIEFMIQTDQQR"
     gene            complement(5743..7080)
                     /locus_tag="BLQ13_RS10345"
                     /old_locus_tag="SAMN05720606_106192"
     CDS             complement(5743..7080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691025.1"
                     /locus_tag="BLQ13_RS10345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106192"
                     /product="hypothetical protein"
                     /protein_id="WP_186809805.1"
                     /transl_table=11
                     /translation="MSNGRNIDDETYKTLSELAYQDQKAGDRLTELPGWQVLEGTESNK
                     FSGFDAVTFYNPETKEAVIAYRGTEGSASLDRSVPDFVMDARIGGGELIRKGQQDTAQF
                     VDNLTPDWLDRGVQNIKDSTGISKVENWAGDRVRDVQNWTGDRVKDIEKTYSPTGWANQ
                     MYQSEDYANHMKEKYGDLNFSLTGHSLGGGDAQYASAYTGLPAVTFSAPSVMGNLTPEM
                     RRRVEAGELDGQVTNYASPGDLVASGTLGGYDRHVGSTYYIDSNYADANNGVSLIDKIK
                     NTFGGENYHSLDQYNFKNGYISNELYDPITGERVRYSPRLMENLGPLSKAVGPMGLRGG
                     AGRGAAAALGSGLIQVTPEELKSVASRWKQNAQQCNAELNQVRTRMAQYLHTSRSRRLE
                     PIVTHLDASIQELSTWHMKHTSQFLNFIEEKAEAFRQADESPVHFN"
     gene            complement(7098..7379)
                     /locus_tag="BLQ13_RS10350"
                     /old_locus_tag="SAMN05720606_106193"
     CDS             complement(7098..7379)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLQ13_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05720606_106193"
                     /product="hypothetical protein"
                     /protein_id="WP_090918839.1"
                     /transl_table=11
                     /translation="MTESEKQALYQEAEKVVVQHFKEKFELDVVVTSKELLPEMAMSQI
                     GLKGHVKDHDDQTFGISYDYKKKITKNLVISPELEEAIKAKGYDPYAK"
     misc_feature    complement(7499..7508)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.24"
                     /tool="antismash"
     gene            complement(7786..10008)
                     /locus_tag="BLQ13_RS10355"
                     /old_locus_tag="SAMN05720606_106194"
     CDS             complement(7786..10008)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="BLQ13_RS10355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106194"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_090918841.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.4e-30, bitscore:
                     97.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKRSVFSRLRGKAQRKIPVKLQMNQYDCGPSCLHMLLAYYGYEA
                     DFTDLKERFAMLGSGRDGSSMLKMKEVAETYHLKGVAKKAPVPSLSNDFLPVICFWEQR
                     HFIVLEEIKAGKLYTIVDPAMGRMTITKQEFEEKYSGIFLLVYPDEGFVPFSEKKMSKV
                     AYFKDLIRSNKKYFVWAVLLALGLQLVSVLFPFLMQVSIDAVTGNEGYSIFPVLITSVA
                     LLTLFQIGFGYVKDMCIVRLQEVLDSQLTTSFVSHMLKLPYQYFEIRSRGDLMMRVNSN
                     VTIREILSQKMISTFINLFLIVVTFTYIVIQSRIIAFTLLGIGITQVLIFVYTRSRFKK
                     LTQTQIVAQSLAGSFMTEVLEGISTIKSLGIEQRTEEKWRELFKRQLATVKEKAIFQTR
                     VNTITNTLNFMTPMLILLVGLYQIMQGNMTLGMLVSFQSLAALFLGPLNSLALMLNEFV
                     MADALLDRIYDVILAEKGRSFQKKPNEMVHVAELQGDITIDHVSFKYTEYSSPVLNDIS
                     MTIKAGQKVALVGRSGSGKSTLAKLLVGLYTPTQGNIYFDGIHAEELDPQHIRDQVSIV
                     LQDNFVFNNTVYDNIKLHAEEATAEEVMFAAKLADIHADIERMPMKYNTLISEAGSNLS
                     GGQKQRVALARALVSRPKILLLDEATSALDTLTESTIAGNLSMLKCTQIIIAHRLSTIR
                     NADTIYVLDQGELVDAGTHEELVTRCDAYQRLVGEQLNEAQLRQYG"
     gene            complement(10001..13345)
                     /locus_tag="BLQ13_RS10360"
                     /old_locus_tag="SAMN05720606_106195"
     CDS             complement(10001..13345)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BLQ13_RS10360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106195"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_090918843.1"
                     /sec_met_domain="DUF4135 (E-value: 8.2e-98, bitscore:
                     322.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.5e-68, bitscore:
                     222.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIQEQLNNSHWGDALYLTEKYKQYELGVAAEPFAHGDAVSSDDV
                     RMKLWLDQFFQDQEQLADRFQAESMDMNKVSSLFQTPDFQYTFTDMGWHQELRKTFLEN
                     EHEDITYFIEGNTEEIPFFEFSQPFLQRSIQIMTEGLSVGYEWLDRRRVIGLVLKTVSD
                     KVFHLSAKTLIYELNKARLQEELIGEDSRQRYLHFVSEKIQSREQILNLLLDYPVLARG
                     IAEHTLRINQNMIRVLERLTADRHELESLFDFKLDRLEDIVFLGDSHNGGASVLRLKFT
                     GDVNVMYKPRDMAIDTAFAGILHWFNEQEMGLPFRITKTLDRSEYGWQQYISYEEVTRE
                     EEAERFFERQGQYLAILYALNATDMHMENIVAQGEHPFFVDLESLLHNQPFKYMDEKEQ
                     YTALEKTLSILNDSVLKTSMLPTLDSNALYHSDLSGLAGDVEQILNTYEVHDKNTDMMR
                     IKRSKIAVSRFSHLPSYNQTPIQPERHIHRLKEGFYRTYRSIMEQKDRFIKAVRHHFHG
                     CAVRTIVRPTVTYFTLIEASSHPKYLRNGLDKSLLFDMMWAIVRQDRNREKLVSYECHD
                     LLHGDVPMFKTLIGEKVLFHHSDNQAIEGVYDSDILTQTETKVRAMNEDDMDMQWEFTE
                     RTLQTKYVLERSFAMEKSTASVRREALNSHPISTTRADYLREAVRIGDYIKDIAITGDE
                     GSTVSWISMGMDADEKLIYKSSELGLYNGVTGIAYFYLYLGQETGEGKYTEMVDLCIQT
                     AWEMIRKNMDRNISLFTGYGSLLYLLVHKAKVYSQQDVHPELLELLDILDEMIEEDERL
                     DVISGCAGTLMACVDLYTMFHLPKALDIATRCADRLLKLAVPMEQGLAWVTSAINKVPL
                     SGIAHGNAGICLSLAHLYRVTGHEPYFEACLEGIKYEESIYSSEVNNWKDLRFTDGNMS
                     EEHYVMYWCNGAPGLGIARVGTAQELSFRGPIDVLEKDIRRAVTKTMEDGFTEVSYSLC
                     HGDMGNLELILLAADYWQDETLEAYAYQMADYIMTKVREDNGHWRCGIPSRQQIPGLML
                     GLAGIGYQLLRLYNRTLPSVLMMEGPVSHELKDVEQVTQQDRVEMAFTRQQEYTAEPSS
                     EPGQHYA"
     gene            complement(13456..13638)
                     /locus_tag="BLQ13_RS10365"
                     /old_locus_tag="SAMN05720606_106196"
     CDS             complement(13456..13638)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016486.4"
                     /locus_tag="BLQ13_RS10365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106196"
                     /product="type A2 lanthipeptide"
                     /protein_id="WP_161556976.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.3e-11, bitscore:
                     38.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQFNLEALAAIEDISDDELMVVTGALAAIEDKKSGGVFCTVSHE
                     CHYNSVSPSSWLTCC"
     CDS_motif       complement(13561..13638)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKQFNLEALAAIEDISDDELMVVTGA"
                     /locus_tag="BLQ13_RS10365_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13456..13560)
                     /prepeptide="core"
                     /locus_tag="BLQ13_RS10365_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="1.70"
                     /molecular_weight="3515.9"
                     /monoisotopic_mass="3513.6"
                     /core_sequence="LAAIEDKKSGGVFCTVSHECHYNSVSPSSWLTCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKQFNLEALAAIEDISDDELMVVTGA"
                     /leader_location="[13560:13638](-)"
                     /alternative_weights="3534.0"
                     /alternative_weights="3552.0"
                     /alternative_weights="3570.0"
                     /alternative_weights="3588.0"
     misc_feature    complement(13817..13826)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(13915..15300)
                     /locus_tag="BLQ13_RS10370"
                     /old_locus_tag="SAMN05720606_106197"
     CDS             complement(13915..15300)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003386947.1"
                     /locus_tag="BLQ13_RS10370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106197"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_090918846.1"
                     /transl_table=11
                     /translation="MDGLVRILRRFVGSTILVSVVLLLFNLVLLGSLIFKEIHEGPSPS
                     AVVKQVAGSLSKSEQGEYTLQSKGMEILAEHQAWAMLLNQEGGVQWSERLPAEIPLTYS
                     VTDVAKFSRYYLKEYPVYVWEREDGLLVLGYPKNTYGKYQFDFLADWLKSLPVRIVLLL
                     ICNVALALLISLLIGTRVIRSIRPLIDGIHALAKGESVQVETKGIFNDLSESINSTSHM
                     LQEKNDALKARDEARSNWISGISHDIRTPLSMILGYASELEEQADLTTEQKQQASIIRR
                     QGERLRSLVSDLNLVSMLEYEMQPLQMRSIRLPVLARQVVSDFLNNGLDERYPISLNVQ
                     DESLYVQGDERLLYRAVTNLVQNSIRHNPEGCAIELMIKREVQSGYAQFIVSDDGKGIP
                     EEDLLDVLVLPYTAGRIRPPRHGHGLGLPMVSRIAQAHRGKLLLQCNSQGGLRAVLELP
                     VVV"
     gene            complement(15300..16013)
                     /locus_tag="BLQ13_RS10375"
                     /old_locus_tag="SAMN05720606_106198"
     CDS             complement(15300..16013)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736110.1"
                     /locus_tag="BLQ13_RS10375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106198"
                     /product="response regulator transcription factor"
                     /protein_id="WP_090918848.1"
                     /transl_table=11
                     /translation="MDIMKNKKILIVDDEPEIREMIERFLRKEGFFRVYTAGNVAHALA
                     MCRIEKPDAAILDIMLPDGDGFSLLSSIRSFSDMPVLFLSARGEDEDRLLGLGLGADDY
                     MVKPFLPRELILRLMGILKRVYASNTIERLPVFRLGGLTIDLESAVVHGNETELPLTAK
                     EHAILVKLYENQNRIVTSDALCQAVWGDESYGYENTLMVHVRRIREKIEEDPSKPVFLL
                     TVRGLGYKLMTQETR"
     gene            16172..17089
                     /locus_tag="BLQ13_RS10380"
                     /old_locus_tag="SAMN05720606_106199"
     CDS             16172..17089
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009673863.1"
                     /locus_tag="BLQ13_RS10380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106199"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_090919037.1"
                     /transl_table=11
                     /translation="MNTSPIVETHNLSKSYGGMNRVHQVNLSVEKGQIFGFLGPNGAGK
                     TTTLKMLLGLIKPSEGTVKVFGKDLTTHRPAILSQTGSLIESPSYYGHLTGLENMKVMQ
                     RLRNVPSKNIDEALKIVRLENQKHKQADQYSLGMKQRLGIAMALLAFPNLLVLDEPTNG
                     LDPAGIGEIRELIKSLPGQYGITVLLSSHLLSEIEQIATSVGIISDGKLLFQGTMQSLQ
                     ANNQATIRFQTSEPAKAEKLLLTHGYMPQVHGNQLILKYLRDEEVSKLNKALVEQSIPV
                     TRIEEHKKSLEDIFLDLTGKERSL"
     gene            17089..17838
                     /locus_tag="BLQ13_RS10385"
                     /old_locus_tag="SAMN05720606_106200"
     CDS             17089..17838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639739.1"
                     /locus_tag="BLQ13_RS10385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106200"
                     /product="ABC transporter permease"
                     /protein_id="WP_090918850.1"
                     /transl_table=11
                     /translation="MKALSLEYYKIRRKKIWIMITLFLAAEMIWAAMSMSISISRSASN
                     ASWEALIFSIASMNGLFLPIISAIVVSRICDMEHKGNTWKMLMTTNTGRNHVYTAKYIC
                     ANSLILYGIIAQAIFIVGFGLSKNISGSIPLSLLVQFVVGTLLTTLAITALQQWLSLTV
                     RNQAFALCLGMLGGFIGTTSGLFPAAIRHLFIWSYYLDLNPVTYIYSASSGTYVSGMLP
                     VGLLLAALCMTIIFYLAGNFHASRQEI"
     gene            17851..18582
                     /locus_tag="BLQ13_RS10390"
                     /old_locus_tag="SAMN05720606_106201"
     CDS             17851..18582
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019423098.1"
                     /locus_tag="BLQ13_RS10390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106201"
                     /product="ABC transporter permease"
                     /protein_id="WP_090918851.1"
                     /transl_table=11
                     /translation="MLRSISAEWLKLRRSRIGLVLAILPVISLLIGCFNFYFNQAALQN
                     GWFSLWTQVSLFYGEFFLPILIAICCAFVCRLEHSNRNWNMVLASPLSVTSLFVAKLVI
                     VGLLIFFAQAFFMLMYWAAGKMFNIPGEFPTEILVWSLRGWFASLSIASLQLGLSIRIR
                     SFATPIGISLCAVFFGLGMYVLKIGMLFPFSLLTIGMGVLSQKGLTTSENMVFLFMNSL
                     FILLFAIWSIRRLKYKDIASS"
     gene            18608..18964
                     /locus_tag="BLQ13_RS10395"
                     /old_locus_tag="SAMN05720606_106202"
     CDS             18608..18964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016133133.1"
                     /locus_tag="BLQ13_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106202"
                     /product="YxeA family protein"
                     /protein_id="WP_261771711.1"
                     /transl_table=11
                     /translation="MMKKSLGILALVLVILTCLWLIFMDPAKLTPDNPAGKTTYYTVVN
                     QTEVNKDENGRYSYKLVGYTDEGKSKTLNFSTGKLLKSGAYLKLYVAAIRGVTHWEEVT
                     ADELPAQAKQLTSK"
     gene            complement(19092..20348)
                     /locus_tag="BLQ13_RS10400"
                     /old_locus_tag="SAMN05720606_106203"
     CDS             complement(19092..20348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818853.1"
                     /locus_tag="BLQ13_RS10400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106203"
                     /product="DUF445 domain-containing protein"
                     /protein_id="WP_090918855.1"
                     /transl_table=11
                     /translation="MAKPKKTKTAAAWSLVIMGAGFAASLPFQGVPVGKLLVGSFEAGL
                     VGGLADWFAVTALFRHPLGIPIPHTALLPKNRDKMTEGLVSAVENNLLNKDSITEKIAG
                     FKAAEIVLDTLGRELHSDGIKTMIDTLCKRILAGLPLEQIAPMVAKEIKSQAGAFDLGP
                     ILERAAVQVTERGYDAQALDYALKQAEEWLVKPETILFLGESGMKAISGIQMNGLMQFA
                     MNAFMGYLNEDRLGGIIQGYLFDRVEDMKREGSALRYKVLDMLRTQAMRIAVSEAVQDG
                     LNGWKNNLLDGWNAEETVLNKLIEMRDKALVAMEDGRYVDTYALPAIEKVLADLRADDA
                     LMTSMNGKIVEGVTTLLEKNHSKIGNLVRENVDKMDNASLISLIEDKVGQDLQWIRING
                     AVTGFIIGVLLTALRMVLE"
     gene            20709..21536
                     /locus_tag="BLQ13_RS10405"
                     /old_locus_tag="SAMN05720606_106204"
     CDS             20709..21536
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012749238.1"
                     /locus_tag="BLQ13_RS10405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106204"
                     /product="aldo/keto reductase"
                     /protein_id="WP_090918857.1"
                     /transl_table=11
                     /translation="MKHVQDTTTLNNGVKMPWLGFGVFKVKDGDEVVNAVKTAIEAGYR
                     SIDTAKVYNNESGVAQGIRESGIAREDLFITTKVWNSDQGYESTLAAFEESMQRLELEY
                     LDLYLIHWPVKGKYKDTWRALEKLYKEGRVRAIGVSNFQTHHLEDLLMDATIKPAVNQV
                     ELHPLLTQKELRDYCSTHEIQIEAWSPLGQGNLMEHPLLQDIAAKYGKSPAQVILRWDL
                     QNGIVTIPKSVTPERIHANTELYDFELTAEEIEQINGLNENKRFGSDPDNFNF"
     gene            21808..22326
                     /locus_tag="BLQ13_RS10410"
                     /old_locus_tag="SAMN05720606_106205"
     CDS             21808..22326
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012818880.1"
                     /locus_tag="BLQ13_RS10410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106205"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_090918859.1"
                     /transl_table=11
                     /translation="MIRLNSRKTKEEQFSEKITTIQNKLYRLAYCYVKNEQEALDIVSE
                     ATYKGYIAYGKMDSMTYFDSWMSRIVINTSIDHIRRSQRVTYMEDYVQEFAAPERGASI
                     EEKMDLYDALDRLVPEDRAYIILKFFDNMRFREIAEVLSLSENTVKSKFYRIINKLKLD
                     LVEGEVGDL"
     gene            22323..23174
                     /locus_tag="BLQ13_RS10415"
                     /old_locus_tag="SAMN05720606_106206"
     CDS             22323..23174
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691031.1"
                     /locus_tag="BLQ13_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05720606_106206"
                     /product="hypothetical protein"
                     /protein_id="WP_090918861.1"
                     /transl_table=11
                     /translation="MTSKERYENIEIPAQLTEVIRQAQRKAAARKKSSRLIRYASALAA
                     CAAFLFIVNIPTVANAMVKIPVVGTIVQVLQFGDGGKITDGVTVGSDATQNTLQIHFST
                     DDQDQTNDAPYYNVVHKSAPNRILFTFSGARYMDMEKVKNDFMTQPLVKDVYGSMILDD
                     SSVGFVVVLKEGVQYSVTEFKNPGYLEVKLTSDGKPVTPRKVFSLRTESMPFGESMGIL
                     KESYPDEDISFLKTSTDEFTAVIGEYSTAEEAELKLKELAKLPEYNGEFYVDSWMSNEN
                     PK"
ORIGIN
        1 gattccgtat attgaattgc atcatgagcg ctatgacggc catggctatc cttacggcct
       61 gaagggtcat gaaattccga agctgtgccg gatgctgacc gtgatcgatt cctttgatgc
      121 catgaccacc gagcgacctt atcagaaaac caaaaatgtg gatgaggcca tagaggagtt
      181 gcggacatgc tcaggtacgc aatttgaccc ggaactcgcg gagttgttca ttcggtatat
      241 cgagaaacga gcggctcatc aactattgca gtagtctgat atatgcataa acgccaaagc
      301 gctatcccca tgagggatag cgccattttc atttttcatc gtgatgtgaa gtgtgatttg
      361 attcatcgaa tgcatcaggg gcctgttcag tcttgtgaag actcctcgtt actcatcgta
      421 ttcagttcat gcgaggtctg atgtaactct ttgatcatct gttgcaaaaa catgttgtct
      481 tggcgactga tcccgtgctg attgtcttga acaagcatct ggtgaatgtt cttcttgagc
      541 aattcactgc gacgttccaa tacttcttga ctcatgttgc tgcgtcactc cttaacatgt
      601 tttgtaatga ttttgcgttc tatataagta tagaggacct tccctcatag cgaaaacggg
      661 cagagccctc ctgagcagag cacatcaacc ctcacctagc gtgacagtat ttcaaccctc
      721 tgtgttctta gatatccttc taaatactcc atgatgctcc cccatttcct gtaaacagcc
      781 cggactaggg tcttggacaa ggttgcgtta taatgatccc attaccctca ttgtggaaaa
      841 ggtacaacct gctacagtat gatgtatcca gcccttaaaa ggagttatgt atatatgtcc
      901 tataaacaga tcaaatggat gatcctgctg attcccacca tcaccgtggg actgtgggaa
      961 tatattcgcc atcagtttct gatgccgtat ctatcgatgg atgccggaaa ctggttgaca
     1021 cctgtgattg tttatcttgt cagcgtgaca ctgctaagcc gtttgttcct gatgttagaa
     1081 ggggcccgag ctgccctcga acaagagcga gcatccaaaa cggcgcttga ggcgcgtgac
     1141 cagcttgccc gggaactgca tgacggcatt tcacaatcgc tattcctgct ctcggtaaag
     1201 accgacaaag caggacgcag tcttgcaggc acgagccatg agcaggatct gcgcgagatt
     1261 caaaaaaccg tgcacgaagt caatacatat gtaaggcaag ccattgccca gttgcgttat
     1321 gtaccttcac ctgttgccga tcccgaagcc gttgctttgc aggctcaggt cgaatctatc
     1381 gtgagtgata ccgttccgga agcagatata gaatggaatc tgaccgaggt ttccttctca
     1441 gccaaagagc aggtagaact gcttgcttgt attcgggaag cactgcttaa cgtacgcaaa
     1501 catgcccatg ctaccaaagt ggaagtttac actaaaggca atgcctctaa ctggtctgtt
     1561 catatccgtg acaatggtat tggaattcag ggcgacccga tgctgttcaa ggaccggtac
     1621 ggtttacgaa tcacaaaaga acgagccgag cagatggggt ggacattcca gcttgattca
     1681 gcatcaggta atacacaaat gatcattgga aaggggcaga cgtgatggaa ctggtacgtg
     1741 tactggttgt tgacgatcac gcacatgcgc gtgaggcgat atgcaccatt ttatccgaag
     1801 atagcctgtt cgaagtcatt ggcacagcca aaaatgggca ggaagcgatt gagttaaccg
     1861 aacactggat gcctgacctg attctgatgg atgtgcagat gcccgatatg gatggactcg
     1921 aagcaacaag gcagattaaa ctgcgtttcc catacgtcat gatcgtaatg gtcaccgtat
     1981 cggatgatgt cacttacctc tttgaagcat tgaaacaagg agcccaaggt tatctacgca
     2041 aaaatttgtc tccttccact tggctggaat accttcgcgc cattgttagt gacgatgcac
     2101 cgctgagcaa ggagctagca taccgaatat tgcaggagtt ccccgctcct cgcagtgagg
     2161 atgtgcaaga gaatccgtta accgctcgcg aattggagat tctgcaatgg gtatctgccg
     2221 ggtacaccaa tcgtgaaatt gccgagcagc tcggcatctc ggatcagacc gtcaagaatc
     2281 atctgaagaa cattctgcag aagctacagc tggagaaccg ggtgcagctc actcgttacg
     2341 cattagagag cgggcttgcc ggccgcaagc ctcgtaaata aagtatgttt cagagcgaat
     2401 agaacaggga attctaccac aaaacgattc acttctgata tgcgttatgt aatagcacca
     2461 cttataaatg tgcatcattt caagcatttg tcacaaatat gcagtaatcc atgatttttt
     2521 atagccctat gtagtcatac gccttcattt tggacaaagt tataatggta tagattatgt
     2581 gtgaacgacg aattatggat aattgtaaat ctataaccca agggtgatga ttttttgaga
     2641 gtaagaagct taaccctgca ttggagcaaa cgtcactggg cactgctcac cagtctgtta
     2701 ctggtgttct gtctggtgat gccgcaatgg gcatctgctc atgcttatat cgtgaaggcg
     2761 tctcctgaag aaaatgaact gctcgttact gccccgcagc ggctgacgtt ggagttcaat
     2821 gaatcattgc agacggcctt ttatgatatt aaaattaccg gacctgacgg caaccaggca
     2881 ggcgacggta acgtacagat tgactcagaa cgcccgcaca ttatggaaac gggtctgaag
     2941 cctggccttg ctgacgggac atatctcgtc aactggaagg ccgtatccgc cgatggtcat
     3001 ccaatctctg gagcgtatgt gtttcatatc ggcgagccta ccggggcacc tgccggattg
     3061 aaggatctgg catccggttc gggtgccacc ggtggcccat tgaaatggat cgtgtcattc
     3121 acggactgga ttcaatatct cggtctgtcc gtcattctcg gtactctagc cttcctgcta
     3181 cttcgaattg caccagcttc cctgctacgg gaaccaatgg aggcaccggg tagctacaaa
     3241 ttgttctgga tcagctatgc tgcttcttct tttgctgcac taataagcct tccgctgaac
     3301 actctctatg agtcaggtgt taatatcggc gaattcagtt gggctttatt aggaagtgcg
     3361 ctcaaactga cctccttcgg tcagatctgg atgttacaga tgctgattgc catgttgctt
     3421 gcagtcacac tactgtccgg ttatgatctg gatcgatccc tgcgcgtgcg aatctggtcc
     3481 tcatacggat cattggtgct ggttctaggc tggctgctta cccatgctat gacggggcat
     3541 cctgctgccg cagagcaacg tgtgcttgct gtagccatgg actttgtaca tcttgccgct
     3601 gctgcattct ggatcggggc tctcaccgct atggcagtgt gtctgccagc actcaccaat
     3661 cgattgcctg caaaactgcg aggtgaagtc tactgggcag cgataaggag atttaccgtt
     3721 tggggtatcg gtgctgtagc cgttctggtc gctacgggta tctatggcag tctggtcatc
     3781 ctgcccgcac cgctactgaa ctctttattc acaacagcat atggcctggt tctgatcggt
     3841 aaaattctgc tacttatcgt gatgatcggt ttcgcgctga ttcatgccaa acgagcaaga
     3901 gccgctacag gtaagcagtt gtctggcagt ctaaaggctg agctggttac aggtgccatc
     3961 attcttgcgc tcgcggctgt actgacacat ctgtctccag gtcagccagc acccgtcggt
     4021 ccttataaag gcacacaaac gacagatgat ggctccgtga taacacttca ggtaagccca
     4081 aacgtagtgg gagaaaatca gttcgaagtc agcataaagc gagcggatgg cagtatcgtc
     4141 aaagatctcg aacaggtgac gttgtctctg atccatctgg atatggatat gggcatctat
     4201 gagatcacca ttccgaagaa cgatacgggc gtatacaagg ctgaggacta catctctatg
     4261 ccgggcaagt ggagtatcca agtccacgcg ttaactcggt cacttgatgc cctcgatgcc
     4321 gagttcaaga ttgaggcagc aaagccgtag taaacaacga aaccattttt aaaagagtga
     4381 agtatatcta aaacatttgc ataagaatga gaggggttct gattttgaaa aagacatcat
     4441 gggtatccaa attaacatct gctatggcaa caggtgcagc agcattcctg ctattctccg
     4501 gtttggccag cgctcacgtc acggtaaatc cgtccgtcgc acaaacgagt gcatggcaga
     4561 catatacgat taaaataccg tctgagaaag agttgccaac aaccaaaatc acactcaaaa
     4621 ttccagaggg tgttgcattt aagcaatatc agccactgtc tggatggaag atcacaactg
     4681 agaaaaatga ttctaaagaa gtaacctcga tcacttggga gattgatgga gataaccaag
     4741 ggattctggc tggacagttc caacagttta actttgttgc acagaaccca aagacagaaa
     4801 cagaagtggc atgggatgcc ttccaatatt acagtgatgg cagcattgta gagtggacag
     4861 gccagccggg ggcaaactct cctcacagca tcacaaccat cagcgaagat ccggcagctg
     4921 ccggtaatgc cgcaacaggc ggatcaagta atgggcatga cagtgcaggc actgctggca
     4981 ccgcgacagg tgacaaagct tctgacactg cgactgatgg caaaaaggga aatgatgaca
     5041 ctactctcgg cgatgctctc tccgatacgg taacaggtca accgaataac acggattccg
     5101 atgcaggtac gttgaagcta caacaagcaa cgttaatcgt atcgatcctg gctctgatca
     5161 tgtccttcct gggcattgca ctggccactc gccgcaaaaa acgttaatct gcagttctct
     5221 tacccggggt cacccgagga gatcattgta aaaagatgca aaaaggagtt tgcagcgaac
     5281 gggataaccc cgttcatgct gcaaactcct tttttagtta atctatgtcc aaaatcgaga
     5341 tgacttgccg tgcacgatac atgcgccatc cgcaatatgg cacaccgttg catattaacg
     5401 ttgctgatcc gtttgaatca taaattcaat atactggatc agacttttct tctgcatctc
     5461 gatggattgg atacgcttgg cgagacctgc gaaaaattct tcaatctgct gcctcgtatg
     5521 atccgcagat tgtcctttcc aatcgttcag acggctgtac agcgcccttg cctcctgctc
     5581 atccgcttgc atgcgaacca gtagctgtga cagctctttt tccgcaatcc gcaggtcatt
     5641 caattccacc agcaattgtc cgctcatccg tggttccctc cccctcagtg cacgttctca
     5701 ccttgaatac tcaatgctat ctctccagcc tgccatttat aactagttaa aatgtaccgg
     5761 actctcatcc gcttgccgga aagcctccgc cttttcctca ataaagttca ggaattggct
     5821 cgtatgcttc atatgccatg tgctcagctc ctggatagac gcatccaagt gagtcacaat
     5881 gggctccagt ctgcggctac ggcttgtatg taaatactga gccatacgtg tccgcacctg
     5941 attcaactcg gcattgcact gctgggcatt ttgtttccag cgggaagcca cacttttcag
     6001 ttcttccggg gtaacctgga ttagaccaga tcccagcgcc gcagccgctc ctctgccggc
     6061 accgcctctc agccccatcg gacctaccgc tttgctcagc ggtcccagat tctccataag
     6121 tcgtggcgaa taacgaaccc gctcacccgt gatcggatca tacaactcgt tggaaatgta
     6181 accatttttg aagttatact gatcgaggct gtgatagttt tctccgccaa atgtattctt
     6241 gattttatca atcagactta caccattatt ggcatctgcg taattcgaat caatataata
     6301 cgtagaacct acatgacgat catatccgcc taacgttccg ctagcgacca gatcgcccgg
     6361 actcgcatag ttcgttactt gcccatccaa ctcaccggcc tcaacccgcc gacgcatctc
     6421 aggagtcaag ttgcccatca ctgaaggtgc actgaatgta accgcaggaa gacctgtata
     6481 agcggaagca tactgcgcat ccccacctcc aagagaatgt cctgtcagag agaaattcag
     6541 atcgccatac ttttctttca tatggttcgc ataatcttcc gactgataca tctggttagc
     6601 ccagcccgta ggcgaatagg tcttttcgat atcctttacg cgatcgcccg tccagttttg
     6661 tacatctctt accctgtcgc cagcccagtt ctctactttg gaaatacctg tggaatcttt
     6721 gatattctga acgcctctat cgagccaatc cggtgtcagg ttgtctacaa attgtgccgt
     6781 gtcttgttgc cctttgcgga tcaattctcc gcccccgatg cgtgcatcca tcacgaaatc
     6841 aggcaccgag cggtccagag aggcactccc ctcggttccc cgataggcaa tgactgcctc
     6901 cttggtctcc ggattataaa acgttacggc atcgaagccg gaaaatttat tactctctgt
     6961 gccctccagt acttgccagc cgggaagctc cgtcagacgg tcacctgcct tttgatcctg
     7021 ataggctaac tccgataagg ttttgtacgt ttcatcatca atgttcctgc cgttactcaa
     7081 tcactgcacc tcccctttta tttggcgtat ggatcatatc ctttagcttt aatggcttcc
     7141 tcgagctcgg gactaatcac gagatttttg gtgatttttt tcttgtaatc gtacgatatg
     7201 ccaaaggtct gatcgtcatg atccttcaca tgccccttca gtccgatctg cgacatcgcc
     7261 atctctggca gcagttcctt gctcgtaacg accacatcca gttcaaactt ttctttgaag
     7321 tgctgcacca caaccttctc agcttcctgg tacaacgcct gtttctcact ctctgtcatc
     7381 ttctgacacc ctcccagcaa tatagtgaac accatcatca gtgcgaataa acttctcatc
     7441 ccttttgtgc gcggaatagc aattccccct tttggctcaa acctgtgtaa gtaaagagcg
     7501 cccccttcac ctgttacatg catcatagta caaaatcaac ataagacaca tccgctcaca
     7561 ggagcgtttt cctgaaactt ttctcctagt tgattcatgc ctatatttgg gtgtatatta
     7621 cccgcttcta agactgctgt accatttagg ccctaacttt ttccatataa aaataaaaaa
     7681 ctttcttccg aacaccggct ggtgtcaaaa agaaagcttg attataaatg acacacctct
     7741 tatccaggcc cagcgaagca gagacaccct cataaataac atgctctatc catattgtct
     7801 gagctgggcc tcgttcaact gctctcctac gagtctctga tacgcgtcac accttgtaac
     7861 caactcttca tgtgttcccg catcgacaag ttctccctga tccagcacat agatcgtgtc
     7921 ggcatttcga atggtgctca gcctgtgagc aataataatt tgcgtacatt tcaacatgct
     7981 taagttcccg gcaatcgtag attccgttaa cgtatccagt gcactggttg cttcatccaa
     8041 aagcagaatt ttgggcctgc tcacaagcgc ccgtgcaaga gctacccgtt gtttctgtcc
     8101 cccggacaga ttagagcctg cctccgaaat taacgtgtta tatttcatcg gcatgcgttc
     8161 gatatctgca tgaatatcgg caagttttgc agcaaacatt acctcttctg cagttgcttc
     8221 ttccgcatgc agcttgatgt tatcgtaaac ggtattgtta aacacgaagt tatcctgaag
     8281 aacgatgctg acttgatcac gaatatgttg aggatctaat tcctccgcat gaatgccatc
     8341 gaaataaata tttccttgtg taggggtgta caaccccact agcaatttag cgagagtact
     8401 tttaccagag ccagatctgc caacgagagc caccttctgt cctgctttaa tggtcatact
     8461 aatgtcatta agcacaggac tactgtactc cgtatatttg aagctcacat ggtcaatcgt
     8521 aatatcaccc tgaagctcgg caacatgcac catctcattt ggtttcttct gaaaagaccg
     8581 acccttttct gccaaaatca catcataaat ccgatccagc aacgcatccg ccattacgaa
     8641 ctcattcagc atcaaggcaa gtgaattaag cggccccaaa aaaagtgcag ccagagactg
     8701 gaatgaaaca agcataccta acgtcatgtt gccctgcata atctggtaca aacccacaag
     8761 caaaatgagc atcggtgtca taaaattcaa agtattggtt atcgtgttaa ctcgagtttg
     8821 aaaaatagcc ttttccttca ccgtggcaag ctggcgttta aataactccc gccatttttc
     8881 ttccgtgcgc tgctcgatac ccagagattt aattgttgaa atcccttcta acacttcggt
     8941 cataaaagat cctgccaagc tctgagctac aatctgagtt tgcgtcagtt ttttgaacct
     9001 gctgcgcgtg tatacaaaaa taagaacctg tgttattcct atacctagca acgtgaacgc
     9061 aataatgcgt gattgaatga caatgtaggt aaacgtcacc acaattaaaa ataaattgat
     9121 gaacgtggaa atcatttttt gcgacaaaat ttcccggatg gtaacattgc tgttgactcg
     9181 catcatcaga tctccccgag agcgaatctc aaaatattga tacgggagct tcaacatgtg
     9241 ggacacaaaa ctggtggtta actgcgaatc cagcacttcc tgaaggcgca cgatacacat
     9301 atctttcaca tatccaaaac cgatctgaaa caaggttaac aaggccacac tggtgatcaa
     9361 cacgggaaaa atggagtatc cctcattgcc cgttaccgca tcaatcgaaa cctgcatcag
     9421 gaacggaaaa agcaccgata caagctgtaa tcccagggca agcaatacgg cccatacaaa
     9481 atactttttg ttgctgcgaa tcaaatcttt gaaatacgct actttactca tctttttttc
     9541 tgaaaaaggg acaaacccct catccgggta taccagcaga aaaatacctg aatatttctc
     9601 ttcgaactcc tgtttagtga tcgtcattct tcccatggca ggatcaacaa tggtatataa
     9661 cttaccagcc ttaatctcct caagcacaat aaaatgtcgt tgctcccaga aacagatgac
     9721 cggcaagaaa tcattgctga gtgaaggcac aggtgccttt ttggctacac ctttcagatg
     9781 gtaggtttcg gctacctcct tcattttcaa catagaactt ccgtcacgac cgctccccag
     9841 catggcaaat cgttccttca gatcggtaaa atcggcttca tagccatagt acgcaagcaa
     9901 catatgcaag cagctgggcc cgcagtcgta ttgattcatt tgcaatttaa caggaatttt
     9961 tcgctgtgcc ttgccacgca gacggctaaa tactgaacgt ttaggcataa tgctgtcccg
    10021 gttcagatga cggctctgcc gtatactcct gctgtctggt aaaagccatc tccactctat
    10081 cctgctgcgt gacctgctct acatccttca gttcatgact taccggccct tccatcataa
    10141 gtaccgaagg cagtgtccga ttatacaacc gcagtaattg gtatccgatc ccggccagac
    10201 ccagcataag tcctggtatt tgttgacgac tcggaatgcc gcatctccag tgaccgttat
    10261 cctctctaac cttggtcatg atataatcag ccatttgata agcgtatgct tctaacgttt
    10321 catcctgcca atagtcggct gcgagcaaga tcagctccaa attccccata tctccgtgac
    10381 atagtgaata actgacttct gtgaaaccat cttccatggt cttggtcacc gctcggcgaa
    10441 tgtctttttc cagcacatct ataggcccgc ggaagcttaa ttcctgtgct gttcctaccc
    10501 gggcaatacc caaaccgggt gcaccattac accaatacat gacataatgt tcttccgaca
    10561 tattgccatc cgtgaaccgg agatccttcc agttattcac ctcggaactg tagatcgatt
    10621 cctcatattt aattccttcc aaacaagctt caaaataagg ttcgtgacct gtaacacggt
    10681 acagatgggc aagactcaga catatgcctg cgtttccatg tgcaatgccg ctaaggggca
    10741 ctttattgat cgccgatgtc acccatgcca agccttgttc catcggcaca gccagcttaa
    10801 gcagccgatc tgcgcatctt gtagctatgt ccagtgcctt aggcaggtgg aacatcgtat
    10861 acaaatccac gcatgccatt aatgtgcctg cacaacctga gatgacatcc agccgctcat
    10921 cttcctcgat catctcatcc agtatatcca gcagttcgag cagttccggg tgaacatcct
    10981 gctgggagta taccttcgct ttatgcacta acaaatagag aagtgatccg taacctgtaa
    11041 acagagagat atttctgtcc atgtttttgc gaatcatctc ccaggccgtc tggatacaca
    11101 aatcgaccat ctctgtatac ttcccttcac ccgtctcttg acctagataa agatagaaat
    11161 aagcgatgcc cgtgacccca ttgtatagac ccagttccga ggatttatag atcagtttct
    11221 cgtccgcatc catgcccatg ctgatccagg atacggtgct gccctcatct cccgtgatcg
    11281 cgatatcctt aatataatca ccaatcctta ccgcttcacg taagtaatca gctcgggtcg
    11341 tggagattgg atggctgttc aacgcctctc gccttacact cgctgtactc ttctccatag
    11401 cgaatgagcg ctccagtaca tacttcgttt gcagagtgcg ctccgtaaat tcccactgca
    11461 tatccatatc atcttcattc atggcccgaa cctttgtctc cgtctgggtc aagatatccg
    11521 agtcatatac accctcaatg gcttgattat ccgaatgatg aaacagcacc ttctcaccaa
    11581 ttaatgtttt gaacataggc acatctccgt gcaacagatc atggcattca taactgacca
    11641 gtttctcacg gttacgatcc tgccggacga tagcccacat catgtcaaac agcagacttt
    11701 tgtccagccc attgcgtaaa tatttaggat gagagctggc ttcgattaat gtaaaatagg
    11761 tcacggttgg ccgaacgatc gtccgcacgg cacacccatg aaaatggtgg cgtaccgcct
    11821 tgatgaaacg gtctttttgc tccatgatgg aacgataagt gcgatagaac ccttctttca
    11881 aacgatggat atggcgttca ggttgtatcg gcgtttgatt gtaagatggc aggtgactga
    11941 accgacttac agcaatcttg cttcgtttga tcctcatcat atctgtgttt ttatcgtgaa
    12001 cctcataagt attgagaatc tgctccacat ctccggcaag cccgctcaga tcactatgat
    12061 acaaggcgtt ggagtccagc gtagggagca tgcttgtttt taatacggaa tcattcaata
    12121 tcgaaagggt cttctccagt gccgtatact gctccttctc atccatatac ttgaagggtt
    12181 gattgtgcag caaagactcc agatcaacga agaacggatg ctctccttgg gcaacaatat
    12241 tttccatatg catatccgtt gcgtttaatg catatagaat cgctaaatat tgtccctgtc
    12301 tctcaaaaaa gcgttctgcc tcttcctccc gggttacttc ctcgtaagaa atatattgct
    12361 gccagccata ctcggaacgg tccagcgttt tggtaatccg gaaaggcaat cccatctcct
    12421 gttcattaaa ccaatgtagt ataccagcaa atgcagtatc aattgccatg tctcttggct
    12481 tgtacatgac attaacgtcc ccggtaaatt tcaaccgcag cacgctggct ccaccattat
    12541 gggaatctcc aagaaatacg atatcctcca gcctgtccag tttaaaatca aacaaagatt
    12601 ccagttcatg acggtcggcc gtcaatcgct ccagaacccg aatcatattc tgattgatcc
    12661 gcaacgtgtg ctcggcaata cctcgggcaa gaaccggata atccagtaac aggttgagaa
    12721 tttgttctct ggactgaatt ttctcgctta caaaatgcaa atatctctgc cgggaatctt
    12781 cacctatcaa ttcctcttgc agtctagctt tatttagttc atagataagt gtcttcgcag
    12841 acaagtgaaa cactttatcc gagacggtct tcagtacaag cccgatgaca cggcgccgat
    12901 ccagccactc atatcctact gacagacctt ctgtcatgat ctgaatagat cgttgcagaa
    12961 aaggttgtga aaattcaaaa aaagggattt cctctgtatt gccctcaatg aaatatgtaa
    13021 tatcctcatg ctcattctca agaaacgtct tccgaagctc ctgatgccag cccatatctg
    13081 taaatgtgta ctggaaatct ggagtttgaa atagactact caccttgttc atgtccatag
    13141 attcagcctg gaatcgatcc gctaattgct cctgatcctg aaagaactga tcaagccaca
    13201 acttcattct tacatcatct gaggagactg cgtctccatg agcgaaaggc tccgcagcaa
    13261 ctccaagttc atactgcttg tatttctctg tcaaatataa agcatcaccc cagtgggagt
    13321 tattcaactg ctcctgtatg ctcatcgttt tctctccctt tctaaatcaa tggttgtaaa
    13381 caggaaaaca ccatataaat acttcaagca cataactgag atcagctatg tgcttgaaga
    13441 aaatcgaagt cagaattaac aacaagtcaa ccaggaagaa ggtgaaacag aattataatg
    13501 gcactcatga ctcactgtgc aaaatacacc accgcttttc ttatcctcaa ttgcggctaa
    13561 cgcccctgta accaccatca gttcatcatc actgatgtcc tcgattgctg ctaatgcttc
    13621 gagattgaat tgtttcattg aaaaaacctc cattcaattt tttgtatatg tatagcttaa
    13681 ataagctaaa caccggagtt cattcaaaca aaacatatat ttacattaaa tataaaatat
    13741 gtaatctatt tctaacttta ctctatcaca ctttgctaga ttttgtaaat ccttattttc
    13801 ccttccttgg attatctaaa aaaataaaat aattcatact tttaaatttt agtatctata
    13861 ttacgttgtt atgcgcacac atttgtaaaa aacctgtcct gagacaggtg aattctatac
    13921 cactacaggc agttctaata ccgcgcgaag ccctccttgg ctgttacact ggagcagaag
    13981 cttcccccga tgggcttgag caatccgtga taccattgga agtccgagac catgcccatg
    14041 acgtggaggt cttatgcgac ctgccgtata aggaagaacc agcacatcaa gcagatcttc
    14101 ctcgggaatt cccttcccat catcggagac tatgaactgt gcgtaaccac tttgcacttc
    14161 acgcttgatc atcaattcga ttgcacaccc ctctggattg tgtctaatgc tgttctgcac
    14221 cagattggtt accgctcggt ataacaatcg ttcatcccct tgcacataca gactttcgtc
    14281 ttgaacattt aacgatatcg gataacgctc gtccagacca ttatttaaaa aatcagatac
    14341 tacttgcctt gccagaacag gcaaccgaat ggatctcatc tgtaggggct gcatttcata
    14401 ctctagcatc gataccagat tcaaatcact gacgagcgat cgcagacgct ccccctgacg
    14461 ccggataatg gatgcctgtt gcttttgctc ggttgttaga tccgcttgct cctccagttc
    14521 actagcatat cccaaaatca tggataatgg cgtccgtata tcatgcgata tccctgatat
    14581 ccagttggat cgtgcctcat cccttgcctt tagcgcatca tttttctcct gtaacatatg
    14641 ggaggtcgag ttaatgcttt cagacaaatc attgaatatg cccttggttt caacctgcac
    14701 cgactctcct ttagcaagtg catgaatgcc atcgatcaac gggcgaatgc ttcgtatgac
    14761 acgggttccg attagcaatg agataagtag cgcaagtgcc acattacata tcaataacag
    14821 tacaatcctg accggtagag acttgagcca atccgccaaa aaatcgaact ggtattttcc
    14881 atacgtattt ttgggatacc ccaacaccaa aagtccatct tcccgttccc acacatatac
    14941 cgggtactct ttaagatagt atcgagaaaa tttagcaaca tcggtcacac tgtaagtaag
    15001 ggggatttct gctggaagac gctcactcca ctgcacccca ccctcctgat tcaaaagcat
    15061 cgcccaggct tgatgctcag cgagaatctc catcccttta ctttgtaatg tgtactcccc
    15121 ctgctcgctc ttgctcaaac tgcctgcgac ctgtttgaca acagcactgg gggaaggtcc
    15181 ttcgtgaatt tccttgaaga tcaatgaacc cagcaatacg agattaaata aaagcagtac
    15241 aacagataca agaatggtag agccgacaaa tcttcttaga atacgaacca aaccatccat
    15301 tatcgagtct cctgagtcat cagtttataa ccaagcccgc ggacggttaa cagaaacact
    15361 ggtttagacg ggtcctcttc gattttctcc cgaatccgcc gaacatgaac cattagggta
    15421 ttctcatatc cgtaactctc atctccccaa acggcctgac atagtgcatc actggttaca
    15481 atccggttct gattctcata aagtttgacc agtatagcgt gctccttggc tgtcagtgga
    15541 agttctgttt cgttcccatg aacgacagcg ctctccaaat caatggttaa tccacctaga
    15601 cgaaatacag gcaatctctc tatcgtattg gaagcgtata cccttttcaa tatgcccatg
    15661 agccgaagaa tcagctctct tggaagaaat ggtttgacca tataatcatc tgctcccaaa
    15721 cctaaaccga gtaaacgatc ctcatcctcc ccccgcgctg acaaaaatag cacaggcatg
    15781 tccgagaagg aacgaataga agacaacaag gagaatccgt ctccatctgg caacatgata
    15841 tccaggatgg ctgcatccgg cttctctatt ctgcacattg ccagagcatg ggccacatta
    15901 cctgcggtat agactctgaa aaagccctcc ttacgcaaaa agcgttcgat catctcacgg
    15961 atttccggtt catcatctac aatcagtatt ttcttgtttt tcattatgtc cattcgtatc
    16021 acccttttca ttatacatca ggacatgaat ataagcctat attttccaat tctatttaag
    16081 gtaaatgtaa ggttatcttc agccaagagc aagacgtctg atctatattg aacttaacag
    16141 agatcaccgt gaaatggaga tgaaatcaat gataaacact tcccccattg tcgaaacgca
    16201 taatctgtcc aaatcatacg gcggtatgaa tcgtgtgcat caagtgaatt tgtcggttga
    16261 gaaggggcaa atttttggat ttctaggccc gaacggagca ggaaaaacga ccacgttaaa
    16321 aatgttgcta gggttgatca aacctagtga aggtacggtc aaggtctttg ggaaagactt
    16381 gaccacacat cgacccgcca ttctgagcca aaccggttca ttgattgaat ccccctcgta
    16441 ttatggtcac ttgaccggtc ttgaaaatat gaaggtgatg cagcggctgc gaaatgtacc
    16501 aagcaaaaat atcgatgaag ccttaaaaat tgtaagactg gaaaatcaga aacataaaca
    16561 ggccgatcag tattcactcg gtatgaaaca acggctgggc attgccatgg ctttacttgc
    16621 ttttcccaac ttgcttgttc tggatgaacc tacgaatggg cttgaccctg ccggtatcgg
    16681 tgaaatcaga gaattgatca agtccctgcc tggtcaatat ggcatcaccg ttttgctatc
    16741 cagccatttg ttatccgaga tcgaacagat cgcaacctcc gtgggcatta tcagtgatgg
    16801 caaattgttg tttcaaggta ccatgcaaag tcttcaggct aataatcagg ccacgatccg
    16861 tttccagacc tccgagccgg caaaagcaga aaagcttcta ctaactcatg gctacatgcc
    16921 acaagttcac ggaaatcagc tcatattgaa gtatcttcgc gacgaagaag tatcgaagct
    16981 gaataaagcg cttgtggaac agagtattcc ggtcactcgt attgaggagc acaaaaagag
    17041 tctggaagac attttccttg atctgactgg aaaggagaga agcctgtaat gaaagcccta
    17101 tctctggagt attacaaaat ccggcgcaaa aagatttgga tcatgattac cctgttcctt
    17161 gctgcagaga tgatctgggc cgccatgtcc atgagcatat cgatctctcg aagcgcgagt
    17221 aatgccagct gggaagcact cattttcagc atcgcttcga tgaacggtct gtttctgccg
    17281 attatatcgg cgatcgtggt gtcccgcatc tgcgatatgg agcataaggg gaacacttgg
    17341 aagatgttaa tgacaaccaa tacgggacgg aatcatgtgt acaccgccaa atatatctgt
    17401 gcaaatagtc tgatcctgta tggcatcata gcgcaggcca tttttatcgt gggctttggt
    17461 ctatccaaaa acatttccgg ttccatccca ctctccctgc ttgtgcaatt tgttgttggg
    17521 acgttactaa ctacacttgc cattacagca ctacagcaat ggttgtcgct gaccgtccgc
    17581 aatcaggcgt ttgctttgtg tctgggcatg ctgggaggat tcatcggaac cacatccggt
    17641 ttgttcccag ccgccattcg tcacttgttt atctggtctt attatctgga tttgaacccg
    17701 gtcacttaca tttacagcgc atcttcagga acctatgtat ctggaatgtt gcctgtcggc
    17761 ctattgttag cggccctgtg catgacgatc atcttctatc ttgctggcaa ttttcatgcc
    17821 tcgagacaag aaatctaagg agggaactat atgctgagga gtatctctgc cgaatggctt
    17881 aaacttcggc gttcccggat cggtctggta ctggcaatcc tgcctgttat cagcctgctt
    17941 atcggatgtt ttaactttta ttttaaccag gccgctttac aaaatggttg gttcagcttg
    18001 tggacacagg tcagtttatt ttacggggaa ttcttcctgc ctattctcat cgccatctgt
    18061 tgtgcctttg tatgccgtct ggagcatagc aaccgcaact ggaacatggt tctggcttcg
    18121 ccgttaagtg tcaccagtct gtttgttgcc aaattggtca ttgttggcct attgatcttt
    18181 ttcgcccaag cctttttcat gctgatgtat tgggctgcgg gcaagatgtt caacattccg
    18241 ggcgagtttc caacggaaat tctggtctgg agcctacgag gatggtttgc ttctctttcc
    18301 atcgcctcac ttcaacttgg gttatccatt cggatacgca gctttgctac acctattggt
    18361 atcagccttt gcgcagtctt ttttggattg ggcatgtatg tattgaagat tgggatgtta
    18421 ttcccgtttt ccctgctcac gatcggtatg ggtgtgctta gtcagaaggg gctgactacc
    18481 tcagagaata tggtttttct atttatgaac agcttgttca ttcttctatt tgccatctgg
    18541 tcgattcgcc gcctgaaata caaagatatt gcatcatcct gaattccaat ccgcaaagga
    18601 gtgtactatg atgaaaaaat cactcggtat tctcgcatta gtacttgtga ttctgacctg
    18661 cctgtggctt attttcatgg acccggctaa actgacacct gataatccgg caggcaaaac
    18721 aacctattat acggttgtga atcagactga agtaaacaag gacgaaaatg gacgatacag
    18781 ctacaaacta gtcggttaca cggatgaggg aaaatccaaa acattaaact tttctacagg
    18841 aaaattactt aaaagtggtg catatttgaa gctctatgta gccgcaatac gtggtgtaac
    18901 tcactgggaa gaagtgacgg cagatgaatt gcccgctcaa gccaagcaac taacctccaa
    18961 ataatccacc tctcatccca agctagcaac aagataacaa accacatcat tacgatgaca
    19021 ctaaaaaaga gcctgctctc cacacgagcg gctcttcttg ctggccagcc agatcggccc
    19081 ggccttccct tttattcaag taccatccgt agcgcggtca gtaagacccc gataataaat
    19141 ccggtcaccg caccgttgat ccgaatccat tgcagatcct gacctacttt atcttcaatc
    19201 agcgagatga gtgaagcatt atccatttta tctacatttt cgcgcacaag attcccgatt
    19261 ttggagtgat ttttctccag cagtgtggtg acaccttcta caattttgcc attcatgctt
    19321 gtcattaacg cgtcatctgc acgcagatcc gctagaactt tttcaatggc aggaagtgca
    19381 tacgtatcta cgtaacgacc atcctccatc gccactagtg ctttatcccg catctcgatg
    19441 agcttgttca gcacggtttc ctcagcattc cagccatcca gcagattatt cttccacccg
    19501 ttaaggccat cctgcacagc ttcactcacc gcaatacgca tggcctgtgt acgaagcata
    19561 tccagcactt tgtaacgcag cgcactgcct tcccgtttca tatcctctac ccggtcaaag
    19621 agatatcctt gaataatgcc gcccagacgg tcttcattca aataacccat gaacgcattc
    19681 atcgcaaact gcatgagtcc attcatctgg ataccactaa tcgctttcat gccactttca
    19741 cccaggaaca gaatcgtttc cggtttgacc agccactcct ctgcctgttt caacgcataa
    19801 tctagagcct gagcatcata ccctcgctct gttacctgta cagcggcccg ttcgagaatc
    19861 ggccccaagt caaacgctcc ggcctgtgac ttgatctctt tggctaccat cggagcgatc
    19921 tgctctagcg gaagcccggc caaaatacgt ttgcagagcg tatcaatcat ggttttgatc
    19981 ccgtcactat gcagctcccg gcccaatgta tccagcacaa tctcagctgc tttgaagcca
    20041 gcaattttct ccgtaatgct gtccttgttg agcagattat tctcgacagc ggagaccaaa
    20101 ccttccgtca tcttatcccg gttcttcggc agtaaggccg tatggggaat cggaatacct
    20161 agcggatggc ggaacagcgc agttactgcg aaccagtccg caagtccacc cacgagtcct
    20221 gcttcaaacg aaccaaccag cagtttacct accggcaccc cctggaatgg caatgatgct
    20281 gcgaaacctg ctcccataat gacgagagac caggctgctg ccgttttggt ttttttaggt
    20341 ttagccatga ttaatttgct cctttatcgt taatcgcacg agctcgactt gtcatacgag
    20401 atcactacgc ttgattgact ttgattatgt aaaagcatac ggactctacg tttgaatcca
    20461 tttctctaaa cgctatcctc tcaggattat aatgtaggat ctataaaata caattcgttc
    20521 ttttttcgta tacttcatct tatcacccac aagcgtcaaa accaaacctc tgcctggcga
    20581 aaaaggataa aacaggggct tttcgcgcga agcttgccta ctcatattta aagagaggaa
    20641 aactttagta taataaggag tgacaacctg tcagcaatcg aaaagaatca gaggaggaat
    20701 gacagatcat gaaacacgtt caggacacaa ccacactcaa caatggagtc aagatgccat
    20761 ggcttggctt tggcgtattc aaagtgaaag acggagatga ggttgtaaat gccgtcaaaa
    20821 cagcgataga agctggatac cgcagcatcg atactgccaa agtatataat aacgaatccg
    20881 gtgtcgctca aggcattcgt gaatctggca ttgctcgtga agatttgttt atcacaacca
    20941 aagtatggaa cagtgaccaa ggctacgaga gcacacttgc cgctttcgaa gaaagcatgc
    21001 aacgtctgga gcttgaatat ctcgatctct acttgatcca ctggcctgtc aaaggcaagt
    21061 acaaagatac atggagagca ctggagaagc tctataaaga aggtcgtgtt cgcgccatcg
    21121 gcgtgagtaa ctttcagact caccacctgg aggacctctt gatggatgcc accatcaaac
    21181 ctgcggtcaa tcaggtcgag cttcatccgc tcctgactca gaaggaacta cgcgactatt
    21241 gcagtacaca tgagattcag attgaagcct ggtctccact tggacaaggt aatctgatgg
    21301 agcatccttt gctccaggac atcgcagcca agtacggtaa gtcaccggca caagtcatat
    21361 tgcgctggga tctgcaaaat ggcatcgtga ccatcccgaa atccgtaaca cctgagcgca
    21421 ttcatgccaa taccgagcta tatgatttcg agttaacagc tgaggagatt gaacagatta
    21481 acggtctgaa cgagaataag cgtttcggtt ccgatccgga caattttaat ttctgacata
    21541 ttgaattgag ctacacccgc cttcgtttct ggaagagcgg gtgttttgat atggttctgc
    21601 gcaggttata gtcacagact tcgttgtgaa aaatgatggt atggtccctt tgtaatagag
    21661 attacatatt ttttttgcaa gccttaaaac tattttgcct ccttatcagt ctaacgggta
    21721 tcaaacaact caagcactct acaccaatcc gggcctggaa tacacgagga cttgaatatt
    21781 atttaggttg atcagggggg aacaagattg attagactga acagcagaaa aacaaaggaa
    21841 gaacagttca gcgaaaaaat aacaacgatc caaaacaaat tatacagact ggcatactgc
    21901 tatgtgaaaa atgaacaaga agcattggac atcgtatccg aagccacata caaaggttat
    21961 attgcttatg gcaaaatgga ttccatgacc tattttgatt cctggatgtc acggattgta
    22021 atcaatacat cgatcgacca tattcgtcgc agccagcgcg taacttatat ggaggattat
    22081 gtgcaagagt tcgcagctcc agagcgagga gcctccatag aagaaaagat ggatctgtac
    22141 gatgcgctcg atcggctcgt gcctgaagat agagcctata tcatattgaa gtttttcgat
    22201 aatatgcgtt ttcgagaaat cgctgaagtg ctctccttat ctgagaatac cgtcaagtca
    22261 aaattttatc ggatcatcaa taaattaaaa ttggatttag ttgaaggaga ggttggagat
    22321 ctatgacaag taaagaacgt tatgaaaaca ttgaaatccc ggctcaactt acagaggtta
    22381 ttcgtcaagc ccagcgaaaa gcggctgctc gcaaaaaatc atctcgtctc attcgctatg
    22441 cttctgctct ggcagcatgt gcagcttttc tgttcatcgt caacattcct acagttgcaa
    22501 atgctatggt caaaatacct gtggtcggaa cgattgttca agtattacaa tttggcgatg
    22561 gcggtaagat taccgatgga gtaaccgtgg gttcggatgc aacgcaaaat acgcttcaaa
    22621 ttcattttag taccgatgac caggatcaga cgaatgacgc accttattat aatgtagtac
    22681 acaagtcagc acccaatcgt atcctcttta cattcagtgg tgcacgttac atggatatgg
    22741 agaaagtaaa aaacgacttc atgactcaac ctttagtaaa agatgtctat ggctccatga
    22801 ttctagacga ctcctccgtc ggattcgttg ttgttttaaa agaaggcgta cagtattccg
    22861 tcacggaatt caagaaccct ggatatttgg aagtgaagct gacttctgac ggcaaaccag
    22921 tcacacctcg aaaggtgttc tcactccgta cagaatcaat gccttttgga gagtccatgg
    22981 gtatattaaa agaatcttat ccggatgagg atatctcctt ccttaaaacg tctacggatg
    23041 agttcacggc tgttatcggt gagtattcta ccgcggaaga agctgaactc aagcttaagg
    23101 aactcgctaa gctaccggag tataatggag agttttatgt agacagctgg atgagtaatg
    23161 aaaatccgaa gtgagcagta ttcgccatcg gacatgcaaa gcattcacaa tgaacatcaa
    23221 gggtgatatg agaaatgtaa gagcaagaaa gaagagcact caaaaaaaac cgattcagat
    23281 gctgaagcat atctgaatcg gttttttaaa tttaaagttt taaatataag cttatccttt
    23341 ggata
//
