LOCUS       NZ_FNAJ01000038        10255 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Myxococcus virescens strain DSM 2260, whole genome shotgun sequence.
ACCESSION   NZ_FNAJ01000038
VERSION     NZ_FNAJ01000038.1
KEYWORDS    WGS; RefSeq.
SOURCE      Myxococcus virescens
  ORGANISM  Myxococcus virescens
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101905.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 02:08:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,594
            CDSs (total)                      :: 7,524
            Genes (coding)                    :: 7,456
            CDSs (with protein)               :: 7,456
            Genes (RNA)                       :: 70
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 15 of 68
            Pseudo Genes (incomplete)         :: 65 of 68
            Pseudo Genes (internal stop)      :: 7 of 68
            Pseudo Genes (multiple problems)  :: 17 of 68
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:03:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 10255
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNAJ01000038.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..10255
                     /db_xref="taxon:83456"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070493_138"
                     /organism="Myxococcus virescens"
                     /strain="DSM 2260"
                     /type_material="type strain of Myxococcus virescens"
     gene            <1..>10255
                     /locus_tag="BLU09_RS37810"
                     /old_locus_tag="SAMN04488504_1381"
     region          1..10255
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..10255
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10255
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:>10255](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..>10255
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             3..>10255
                     /NRPS_PKS="Domain: nMT (183-404). E-value: 7.4e-110. Score:
                     359.1. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_nMT.1"
                     /NRPS_PKS="Domain: PCP (614-683). E-value: 4.4e-26. Score:
                     82.9. Matches aSDomain: nrpspksdomains_BLU09_RS37810_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (707-1007). E-value:
                     3.4e-115. Score: 376.1. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1171-1568). E-value:
                     1.1e-111. Score: 365.2. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1674-1742). E-value: 1.8e-26.
                     Score: 84.1. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1763-2064). E-value:
                     5.3e-115. Score: 375.4. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2228-2625). E-value:
                     2.6e-108. Score: 354.2. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2730-2798). E-value: 3.4e-25.
                     Score: 80.0. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_PCP.3"
                     /NRPS_PKS="Domain: Condensation_LCL (2819-3119). E-value:
                     7.3e-115. Score: 375.0. Matches aSDomain:
                     nrpspksdomains_BLU09_RS37810_Condensation_LCL.3"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015349700.1"
                     /locus_tag="BLU09_RS37810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_1381"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_143043283.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-119, bitscore:
                     385.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-19, bitscore:
                     54.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.4e-83, bitscore:
                     264.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRVPIGRPVANTVLYVLDTHGQPAPVGIPGELHIGGVQVGRGYW
                     QRPQLTAERFIPDAFSGIPGARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFRIELGE
                     VETALAADRAVRDSVVLAREDSTGDQRLVAYVVLDDAAAAQEVDASSQWQAIYDEAYAR
                     ETTESEDPTFNIVGWEDSYTGESLPPAQMREWVDTTVAQILGFQPKRVLELGCGTGLLL
                     YRLAPRCEAYWGVDFARPALDRIERQRERMGGALDSVHLLHRSVDDFSGLEPGSFDTVV
                     INSVVQYFSSPEFLLDVLRGAVRVLKPGGRVFLGDVRSLELLEAFRASVRLHRTAGPVA
                     TSQFAYRVQRDILAEKELVLSPAFFTALPERIPGIQRVEVLPKHGRYDNELSRFRYEVI
                     LHVGDAAKTPVRRTKPDWVDGAGLTLDGLREQLSARPGLLAVRGLPNARVLESTRLVEL
                     LSATPPPTVAGLREALRDWPGPRGVEPEDLYVLGSELGYEVRVSWASAHRDGALDVVFA
                     RPDEVGTLDLSPEPKQVTSWDGLASDPLRGARSAQAVSRLRDALAAKLPPHMVPSAFVV
                     LPALPLSPNGKVDRKALPAPEAERLGAADAFIAPRTPTEEKVARIFGEILGQSRVGAND
                     DFFALGGHSLLATQVVVRVRAQLNTEISLRTLFDAPTVARLAERIESQAQLADAPGVPA
                     LVPLERGPSAAEGLAASFAQQRLWFLEQLHPGQAAYNLPAALRLTGPLDVEALRRTFLE
                     VVRRHEAVRTTFVTREGQPVQRIHPAPAEWPLPEEDLRGLEPEARDAALQARMAEEAHH
                     AFDLEKGPLLRTVLLRTGADAHVLLLCMHHIISDGWSVGVLVREVAALYGALSQRREAA
                     LPALSVQYADYAAWQRRVLEGPALAPQLDWWRSRLEGAPSLELPTDHARPAVRSGKGAS
                     YFFTLSSEQVAGLERVASAHNATLYMVLMAGWQALLARYSGQTDFCVGTSVAHRTRPEL
                     EGLIGFFVNTLALRANVDGDPRFDDLLARVREESLAAFANQDVPFDRLVEVLGGQRDLS
                     RTPLFQAAFVLQNAPMQPPTLPGMVVDVLHTGTDTARFDVTALLVERGGRLEGELEYSL
                     DLFTPETARRMVEHFQRLLRGVVEDASRRISAVPLWSEAERHEVLVAWNDTAAPYPADT
                     TVHQCFTEQALRTPQAIAVEHEGRSLTYAELDARSNQLAHHLRSLGLGAESRVGVFLHR
                     GLDLLVGLLGILKAGGAYVPLDPSYPAQRLAFMAEDSGVAAILTESALEDELPAGSQLI
                     VVLDEEWARIERQPSTPVTGGLVSPEQLAYITYTSGSTGMPKGVAIPHRGVVRLLIGSR
                     FVDLGPSEVVLQLAPLAFDASTLEIWGALLHGARLVLYPQRTPDLAELGQALVRHQVSV
                     LWLTAALFEQMQQHQPEALGTVRQLLAGGDVLPAPRVRERLAQGVGLVNGYGPTEGTTF
                     TACHRMAPGDAVGDSVSIGRPIANTQVYVLDSEMQAVPVGVPGEVLIGGDGLARGYLGQ
                     PALTAERFVPNPFGSPGARLYRSGDRARWQADGTLQFLGRVDFQVKLRGFRIELGEVEA
                     ALRNHSAVETAIAVVREDIPGDRRLVAYVTPENVDTASVREHLRQRLPEYMVPNAVVAL
                     STLPLSPNGKVDRKALPAPDLVGLGAEDFVAPRTELEQQLAVLFSEVLGLERTGLNDDF
                     FELGGHSLLATQVVTRLRAQLGVDLPLRTFFEAPTVARLAARLESAPRTSTLLPLEPLP
                     RPAQGEATFDVSFAQQRLWFIEQLHPGQFTYNVPAALQLKGRLDEEALRRTFLEVVRRH
                     EAVRTTFVMREGQPAQRIHPAPAEWPLPVEDLSGLEPEARDAAAQARMVEEAHRAFDLE
                     KGPLLRTVLLRTGPDVHVLLLSMHHIISDGWSMGVLVREVAALYESLSQGRDAVLPVLT
                     VQYADYAAWQRRVLEGPALTPQLDWWRSRLEGAPTLELPTDHPRPAVRTLRGATHTFTL
                     PPSLVAGLERVASAHNATLYMVLMAGWQALLARYSGQTDFCVGTPVAHRSRPELEGLIG
                     FFVNTLALRANVDGDPRFEDLLARVREESLAAFANQDVPFDRLVEVMGGQRDLSRTPLF
                     QAAFVLQNAPMQPPTLPGLVVDVLRTGTDTARFDVSALLVERGGRLEGELEYSLDLFTP
                     ETARRIVEHFQRLLEGVVEDASRRISAVPLWSEAERHEVLVAWNDTAAPYPADTTVHQR
                     FMEQARRTPERVAVTFEGRSLTYAELDARSNQLARHLVSLGLGPEARIGVCASRGLELV
                     IGVLGALKAGGCYVPLDPSWPVKRLEHATSTARLSAVLTWQSLLPSLEDGPWHVVALDA
                     DAADIARQSPEAVQVPVFPEGLAFATFTSGSTGTPKGVAVPHRGLLRLSEGSRFLTQAP
                     EEVTLQLAPVAFDVSSIELWGTLLHGGKLVVYPPGTPEPDAVARLIVEHKVSWLVLATS
                     LFDLLQQHQPEVLARVPNLLMGGEAMPAPRARERLARGGALTNGYGPTECSTMATRHTL
                     SPGDSVGRSVPIGRPIDNTEVYVLDPALRPVPVGVPGELCLGGPGLARGYLNRPDLTAE
                     RFVPHPFSAAPGARLYRTGDRVRWSPDGVLEFLGRLDHQVKVRGFRIELGEIEAVLRAH
                     PSVVEATAVVREDASGSNRVVAYVVPPQADVAPLREYLHQHLPDYMVPSAFVGLDAFPL
                     TPNGKVDRKALPAPDLGLGAADYVEPRTELEQQLAALFREALGLERVGLNDDFFLMGGH
                     SLLATQVVTRLRAQLGVDLPLRTFFEAPTVARLAARLESAPRTGTLLPLESLPRPAQGE
                     ATFDVSFAQRRLWFIEQLHPGQVTYNMPAALRLTGRLDEEALRRTFLEVVRRHEAVRTT
                     FVTREGQPVQRIHPAPAEWPLPVEDLSGLEPDARDAAVQVRIAEEAHHAFDLKQGPLLR
                     TVLLRTGPDVHVLLLCMHHIISDGWSMGVLVREVAALYEALSQGRESPLPALTVQYADY
                     AVWQRRVLEGPALAPQLAWWRSRLEGVPTLELPTDHVRPAVSSAKGTSYFFSLSAELVA
                     GLERVGSAHNATLYMVLMAGWQALLARYSGQTDFCVGTSVAHRTRPELDGLIGFFVNTL
                     ALRCRLNGNPTFAELVVRVRDEALGAFAHQDVPFEQLVDAVGGERDLSRTPLFQTLFVL
                     LNSDLIQAPSLPGLHVDVLPSATDTARYDLTLAMRARGGELEGQLEYSQDLFTADTARR
                     MVEHLRVLLSAVADGAGSQRLSALTMMEAQERQQVLSTWNATQAAYPVDATVPSLFTEQ
                     ALRTPQAIAVEHEGRTLTYAELDARSNQLAHHLRSLGLGAESRVGVFLHRGLDLLVGLL
                     GILKAGGAYVPLDASYPAQRLAFMAEDSGVAAILTESSLEDELPAGSQLIVVLDEEWAR
                     IERQPSTPVT"
     CDS_motif       79..168
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0001"
                     /evalue="5.70E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="55"
                     /protein_start="25"
                     /score="50.6"
                     /tool="antismash"
                     /translation="PVGIPGELHIGGVQVGRGYWQRPQLTAERF"
     CDS_motif       256..321
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0002"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="106"
                     /protein_start="84"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YLGRADFQVKLRGFRIELGEVE"
     aSDomain        553..1215
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="7.40E-110"
                     /label="BLU09_RS37810_nMT.1"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="404"
                     /protein_start="183"
                     /score="359.1"
                     /tool="antismash"
                     /translation="GESLPPAQMREWVDTTVAQILGFQPKRVLELGCGTGLLLYRLAPR
                     CEAYWGVDFARPALDRIERQRERMGGALDSVHLLHRSVDDFSGLEPGSFDTVVINSVVQ
                     YFSSPEFLLDVLRGAVRVLKPGGRVFLGDVRSLELLEAFRASVRLHRTAGPVATSQFAY
                     RVQRDILAEKELVLSPAFFTALPERIPGIQRVEVLPKHGRYDNELSRFRYEVILHVGD"
     aSModule        553..2052
                     /domains="nrpspksdomains_BLU09_RS37810_nMT.1"
                     /domains="nrpspksdomains_BLU09_RS37810_PCP.1"
                     /incomplete
                     /locus_tags="BLU09_RS37810"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       1759..1785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0003"
                     /evalue="2.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="594"
                     /protein_start="585"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        1846..2052
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_PCP.1"
                     /evalue="4.40E-26"
                     /label="BLU09_RS37810_PCP.1"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="683"
                     /protein_start="614"
                     /score="82.9"
                     /tool="antismash"
                     /translation="EEKVARIFGEILGQSRVGANDDFFALGGHSLLATQVVVRVRAQLN
                     TEISLRTLFDAPTVARLAERIESQ"
     aSDomain        2125..3024
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.40E-115"
                     /label="BLU09_RS37810_Condensation_LCL.1"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1007"
                     /protein_start="707"
                     /score="376.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="LAASFAQQRLWFLEQLHPGQAAYNLPAALRLTGPLDVEALRRTFL
                     EVVRRHEAVRTTFVTREGQPVQRIHPAPAEWPLPEEDLRGLEPEARDAALQARMAEEAH
                     HAFDLEKGPLLRTVLLRTGADAHVLLLCMHHIISDGWSVGVLVREVAALYGALSQRREA
                     ALPALSVQYADYAAWQRRVLEGPALAPQLDWWRSRLEGAPSLELPTDHARPAVRSGKGA
                     SYFFTLSSEQVAGLERVASAHNATLYMVLMAGWQALLARYSGQTDFCVGTSVAHRTRPE
                     LEGLIGFFVNTLALRANVD"
     aSModule        2125..5229
                     /complete
                     /domains="nrpspksdomains_BLU09_RS37810_Condensation_LCL.1"
                     /domains="nrpspksdomains_BLU09_RS37810_AMP-binding.1"
                     /domains="nrpspksdomains_BLU09_RS37810_PCP.2"
                     /locus_tags="BLU09_RS37810"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2134..2166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0004"
                     /evalue="7.70E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="721"
                     /protein_start="710"
                     /score="9.0"
                     /tool="antismash"
                     /translation="SFAQQRLWFLE"
     CDS_motif       2185..2301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0005"
                     /evalue="2.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="766"
                     /protein_start="727"
                     /score="58.6"
                     /tool="antismash"
                     /translation="AAYNLPAALRLTGPLDVEALRRTFLEVVRRHEAVRTTFV"
     CDS_motif       2521..2586
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0006"
                     /evalue="2.10E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="861"
                     /protein_start="839"
                     /score="39.3"
                     /tool="antismash"
                     /translation="MHHIISDGWSVGVLVREVAALY"
     CDS_motif       2635..2673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0007"
                     /evalue="2.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="890"
                     /protein_start="877"
                     /score="16.8"
                     /tool="antismash"
                     /translation="QYADYAAWQRRVL"
     CDS_motif       2923..3012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0008"
                     /evalue="3.70E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1003"
                     /protein_start="973"
                     /score="48.2"
                     /tool="antismash"
                     /translation="DFCVGTSVAHRTRPELEGLIGFFVNTLALR"
     CDS_motif       3061..3180
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0009"
                     /evalue="4.00E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1059"
                     /protein_start="1019"
                     /score="64.2"
                     /tool="antismash"
                     /translation="REESLAAFANQDVPFDRLVEVLGGQRDLSRTPLFQAAFVL"
     CDS_motif       3517..3564
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0010"
                     /evalue="4.70E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1187"
                     /protein_start="1171"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="FTEQALRTPQAIAVEH"
     aSDomain        3517..4707
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_AMP-binding.1"
                     /evalue="1.10E-111"
                     /label="BLU09_RS37810_AMP-binding.1"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1568"
                     /protein_start="1171"
                     /score="365.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FTEQALRTPQAIAVEHEGRSLTYAELDARSNQLAHHLRSLGLGAE
                     SRVGVFLHRGLDLLVGLLGILKAGGAYVPLDPSYPAQRLAFMAEDSGVAAILTESALED
                     ELPAGSQLIVVLDEEWARIERQPSTPVTGGLVSPEQLAYITYTSGSTGMPKGVAIPHRG
                     VVRLLIGSRFVDLGPSEVVLQLAPLAFDASTLEIWGALLHGARLVLYPQRTPDLAELGQ
                     ALVRHQVSVLWLTAALFEQMQQHQPEALGTVRQLLAGGDVLPAPRVRERLAQGVGLVNG
                     YGPTEGTTFTACHRMAPGDAVGDSVSIGRPIANTQVYVLDSEMQAVPVGVPGEVLIGGD
                     GLARGYLGQPALTAERFVPNPFGSPGARLYRSGDRARWQADGTLQFLGRVDFQVKLR"
     CDS_motif       3703..3744
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0011"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1247"
                     /protein_start="1233"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       3940..3999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0012"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1332"
                     /protein_start="1312"
                     /score="26.7"
                     /tool="antismash"
                     /translation="AYITYTSGSTGMPKGVAIPH"
     CDS_motif       4498..4587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0013"
                     /evalue="1.90E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1528"
                     /protein_start="1498"
                     /score="52.1"
                     /tool="antismash"
                     /translation="PVGVPGEVLIGGDGLARGYLGQPALTAERF"
     CDS_motif       4672..4737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0014"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1578"
                     /protein_start="1556"
                     /score="35.2"
                     /tool="antismash"
                     /translation="FLGRVDFQVKLRGFRIELGEVE"
     CDS_motif       4942..4968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0015"
                     /evalue="2.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1655"
                     /protein_start="1646"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        5026..5229
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_PCP.2"
                     /evalue="1.80E-26"
                     /label="BLU09_RS37810_PCP.2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1742"
                     /protein_start="1674"
                     /score="84.1"
                     /tool="antismash"
                     /translation="EQQLAVLFSEVLGLERTGLNDDFFELGGHSLLATQVVTRLRAQLG
                     VDLPLRTFFEAPTVARLAARLES"
     aSDomain        5293..6195
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.30E-115"
                     /label="BLU09_RS37810_Condensation_LCL.2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2064"
                     /protein_start="1763"
                     /score="375.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="TFDVSFAQQRLWFIEQLHPGQFTYNVPAALQLKGRLDEEALRRTF
                     LEVVRRHEAVRTTFVMREGQPAQRIHPAPAEWPLPVEDLSGLEPEARDAAAQARMVEEA
                     HRAFDLEKGPLLRTVLLRTGPDVHVLLLSMHHIISDGWSMGVLVREVAALYESLSQGRD
                     AVLPVLTVQYADYAAWQRRVLEGPALTPQLDWWRSRLEGAPTLELPTDHPRPAVRTLRG
                     ATHTFTLPPSLVAGLERVASAHNATLYMVLMAGWQALLARYSGQTDFCVGTPVAHRSRP
                     ELEGLIGFFVNTLALRANVD"
     aSModule        5293..8397
                     /complete
                     /domains="nrpspksdomains_BLU09_RS37810_Condensation_LCL.2"
                     /domains="nrpspksdomains_BLU09_RS37810_AMP-binding.2"
                     /domains="nrpspksdomains_BLU09_RS37810_PCP.3"
                     /locus_tags="BLU09_RS37810"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5305..5334
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0016"
                     /evalue="1.20E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1777"
                     /protein_start="1767"
                     /score="8.5"
                     /tool="antismash"
                     /translation="SFAQQRLWFI"
     CDS_motif       5359..5472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0017"
                     /evalue="6.10E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1823"
                     /protein_start="1785"
                     /score="50.8"
                     /tool="antismash"
                     /translation="TYNVPAALQLKGRLDEEALRRTFLEVVRRHEAVRTTFV"
     CDS_motif       5692..5757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0018"
                     /evalue="3.60E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1918"
                     /protein_start="1896"
                     /score="41.8"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVLVREVAALY"
     CDS_motif       5806..5844
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0019"
                     /evalue="2.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="1947"
                     /protein_start="1934"
                     /score="16.8"
                     /tool="antismash"
                     /translation="QYADYAAWQRRVL"
     CDS_motif       6094..6183
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0020"
                     /evalue="1.80E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2060"
                     /protein_start="2030"
                     /score="52.4"
                     /tool="antismash"
                     /translation="DFCVGTPVAHRSRPELEGLIGFFVNTLALR"
     CDS_motif       6232..6351
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0021"
                     /evalue="1.50E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2116"
                     /protein_start="2076"
                     /score="59.2"
                     /tool="antismash"
                     /translation="REESLAAFANQDVPFDRLVEVMGGQRDLSRTPLFQAAFVL"
     aSDomain        6688..7878
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_AMP-binding.2"
                     /evalue="2.60E-108"
                     /label="BLU09_RS37810_AMP-binding.2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2625"
                     /protein_start="2228"
                     /score="354.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FMEQARRTPERVAVTFEGRSLTYAELDARSNQLARHLVSLGLGPE
                     ARIGVCASRGLELVIGVLGALKAGGCYVPLDPSWPVKRLEHATSTARLSAVLTWQSLLP
                     SLEDGPWHVVALDADAADIARQSPEAVQVPVFPEGLAFATFTSGSTGTPKGVAVPHRGL
                     LRLSEGSRFLTQAPEEVTLQLAPVAFDVSSIELWGTLLHGGKLVVYPPGTPEPDAVARL
                     IVEHKVSWLVLATSLFDLLQQHQPEVLARVPNLLMGGEAMPAPRARERLARGGALTNGY
                     GPTECSTMATRHTLSPGDSVGRSVPIGRPIDNTEVYVLDPALRPVPVGVPGELCLGGPG
                     LARGYLNRPDLTAERFVPHPFSAAPGARLYRTGDRVRWSPDGVLEFLGRLDHQVKVR"
     CDS_motif       6874..6915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0022"
                     /evalue="2.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2304"
                     /protein_start="2290"
                     /score="14.5"
                     /tool="antismash"
                     /translation="LGALKAGGCYVPLD"
     CDS_motif       7108..7167
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0023"
                     /evalue="1.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2388"
                     /protein_start="2368"
                     /score="23.6"
                     /tool="antismash"
                     /translation="AFATFTSGSTGTPKGVAVPH"
     CDS_motif       7666..7755
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0024"
                     /evalue="2.80E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2584"
                     /protein_start="2554"
                     /score="61.1"
                     /tool="antismash"
                     /translation="PVGVPGELCLGGPGLARGYLNRPDLTAERF"
     CDS_motif       7843..7908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0025"
                     /evalue="6.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2635"
                     /protein_start="2613"
                     /score="37.4"
                     /tool="antismash"
                     /translation="FLGRLDHQVKVRGFRIELGEIE"
     CDS_motif       8113..8139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0026"
                     /evalue="2.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2712"
                     /protein_start="2703"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        8194..8397
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_PCP.3"
                     /evalue="3.40E-25"
                     /label="BLU09_RS37810_PCP.3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2798"
                     /protein_start="2730"
                     /score="80.0"
                     /tool="antismash"
                     /translation="EQQLAALFREALGLERVGLNDDFFLMGGHSLLATQVVTRLRAQLG
                     VDLPLRTFFEAPTVARLAARLES"
     aSDomain        8461..9360
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLU09_RS37810_Condensation_LCL.3
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.30E-115"
                     /label="BLU09_RS37810_Condensation_LCL.3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3119"
                     /protein_start="2819"
                     /score="375.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="TFDVSFAQRRLWFIEQLHPGQVTYNMPAALRLTGRLDEEALRRTF
                     LEVVRRHEAVRTTFVTREGQPVQRIHPAPAEWPLPVEDLSGLEPDARDAAVQVRIAEEA
                     HHAFDLKQGPLLRTVLLRTGPDVHVLLLCMHHIISDGWSMGVLVREVAALYEALSQGRE
                     SPLPALTVQYADYAVWQRRVLEGPALAPQLAWWRSRLEGVPTLELPTDHVRPAVSSAKG
                     TSYFFSLSAELVAGLERVGSAHNATLYMVLMAGWQALLARYSGQTDFCVGTSVAHRTRP
                     ELDGLIGFFVNTLALRCRL"
     CDS_motif       8473..8502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0027"
                     /evalue="2.30E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2833"
                     /protein_start="2823"
                     /score="7.7"
                     /tool="antismash"
                     /translation="SFAQRRLWFI"
     CDS_motif       8527..8640
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0028"
                     /evalue="5.70E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2879"
                     /protein_start="2841"
                     /score="54.1"
                     /tool="antismash"
                     /translation="TYNMPAALRLTGRLDEEALRRTFLEVVRRHEAVRTTFV"
     CDS_motif       8860..8925
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0029"
                     /evalue="3.60E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="2974"
                     /protein_start="2952"
                     /score="41.8"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVLVREVAALY"
     CDS_motif       8974..9012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0030"
                     /evalue="9.90E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3003"
                     /protein_start="2990"
                     /score="18.0"
                     /tool="antismash"
                     /translation="QYADYAVWQRRVL"
     CDS_motif       9262..9351
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0031"
                     /evalue="2.70E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3116"
                     /protein_start="3086"
                     /score="45.4"
                     /tool="antismash"
                     /translation="DFCVGTSVAHRTRPELDGLIGFFVNTLALR"
     CDS_motif       9400..9519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0032"
                     /evalue="5.50E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3172"
                     /protein_start="3132"
                     /score="70.2"
                     /tool="antismash"
                     /translation="RDEALGAFAHQDVPFEQLVDAVGGERDLSRTPLFQTLFVL"
     CDS_motif       9859..9909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0033"
                     /evalue="2.30E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3302"
                     /protein_start="3285"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="LFTEQALRTPQAIAVEH"
     CDS_motif       10048..10089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLU09_RS37810_0034"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BLU09_RS37810"
                     /protein_end="3362"
                     /protein_start="3348"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
ORIGIN
        1 cttccaccgc gtccccattg gccgccccgt agccaatacg gtgctgtacg tgttggacac
       61 gcatgggcag ccggctccgg tgggcatccc gggcgagctg cacatcggcg gcgtgcaggt
      121 gggacgcggc tactggcagc gaccgcagtt gacggcggag cgcttcattc ccgacgcctt
      181 cagcggcata ccgggcgcgc gcctgtaccg caccggagac gtggcgcggt ggttgccgga
      241 cggcacgctg gagtacctgg gccgggccga cttccaggtg aagctgcgcg gcttccgcat
      301 cgagctgggt gaagtcgaga ccgcgcttgc cgcggaccgg gccgtccgcg actccgtggt
      361 gctggctcgt gaggattcga cgggtgacca gcgattggtg gcctacgtcg tcctggacga
      421 tgcggcggca gcgcaggagg tcgacgcgtc ctcgcagtgg caggccatct acgacgaggc
      481 ctacgcacgc gagacgacgg agagcgaaga cccgaccttc aacatcgttg gctgggagga
      541 cagctacacc ggcgagtcgc tgccgcccgc gcagatgcgt gagtgggtgg acaccaccgt
      601 ggcgcagatc ctcggcttcc agcccaagcg ggtgctggag ctggggtgcg gcaccggcct
      661 cctcttgtac cggctggcgc ctcgctgcga ggcctactgg ggcgtcgatt tcgcccggcc
      721 ggccctggac cgcatcgagc gccagcgtga gcgcatgggc ggcgctctgg attccgtgca
      781 cctgctgcac cggagcgtgg acgacttctc tggcctggag ccgggctcgt tcgacacagt
      841 cgtcatcaac tcggtcgtcc agtacttctc cagccctgag ttcctgctcg acgtgcttcg
      901 cggggccgtg cgcgtcctga agccaggggg ccgggtgttc ctgggtgacg tgcggagcct
      961 ggagctgctc gaagccttcc gtgcctcggt gcgcttgcac cggaccgcgg gccccgtcgc
     1021 cacgtcccag ttcgcctatc gcgtccagcg cgacatcctg gcggagaagg aactggtcct
     1081 ctcccctgcc ttcttcaccg cccttccaga gcgcatcccg ggcatccagc gcgtggaggt
     1141 gctgccgaag cacgggcgct acgacaacga gctcagccgc ttccgctacg aggtcatcct
     1201 ccacgtcggc gacgcggcca agactcccgt ccggcgcacg aagccggact gggtggacgg
     1261 cgccggactc accctggacg gactgcgcga acaactgagc gcacggcctg ggctgctggc
     1321 cgtgcggggg ctccccaacg cgcgagtcct ggagtccact cggctcgttg aactgctgtc
     1381 cgccacgcct ccgcccacgg tggcggggct tcgcgaggcc ctgcgtgact ggccgggtcc
     1441 ccgcggcgtg gagccggagg acctgtacgt tctgggctcg gagctcggct acgaggtccg
     1501 ggtgagctgg gcctccgcgc accgggatgg tgcgctggac gtggtgttcg ctcgccccga
     1561 tgaggtgggc acgctcgact tgtcccccga acccaagcag gtcacctcct gggatggcct
     1621 tgccagcgat ccgctgcgcg gggctcggag tgcacaggcg gtgagccgtc tccgcgacgc
     1681 gctggcggcc aagctgccgc cgcacatggt gccctccgcc ttcgtggtgc tgcccgccct
     1741 gcccttgtct cccaatggca aggtcgaccg caaggcactg cccgcgccag aggccgagcg
     1801 cctgggcgcc gcggacgcct tcatcgcgcc ccggacgccc accgaggaga aggtggcgcg
     1861 catcttcggt gagattctgg gccagtcccg agtcggcgcg aacgatgact tcttcgcgct
     1921 ggggggccac tccctgttgg ccacgcaggt ggtcgtgcgc gtgcgcgcgc agctcaacac
     1981 ggagatctcg ctgcggaccc tgttcgacgc gcccaccgtg gcccgtctgg cggagcgcat
     2041 cgaatcgcaa gcccaactgg ccgacgcacc gggtgtcccg gcactggtcc cgctggagcg
     2101 cggtccgtcc gctgccgaag gactggcggc ttccttcgcg cagcaacggc tctggttcct
     2161 ggagcagctg caccccgggc aggccgccta caacctcccc gcggccctgc ggctgacggg
     2221 accgttggat gtggaggccc tgcggcgcac cttcctggaa gtggtccgcc gtcacgaagc
     2281 ggtgcgcacc actttcgtca cgcgcgaagg acaaccggtc cagcgcatcc acccggcgcc
     2341 ggctgaatgg ccgctgcccg aggaggacct gcgcggcctg gagcccgagg cccgcgacgc
     2401 ggccctgcag gcccggatgg ccgaagaggc ccaccacgcc ttcgacttgg agaagggtcc
     2461 gttgctgcgc acggtgctgc tgcgcaccgg cgcggacgcg catgtgctgc tgctgtgcat
     2521 gcaccacatc atctcggacg gctggtccgt tggcgtgctg gtgcgggaag tggccgcgct
     2581 ctacggagcg ctgtctcagc ggcgtgaggc cgcgctgccc gcgttgtcgg tgcagtacgc
     2641 ggactacgcc gcgtggcagc ggcgcgtact ggaaggcccg gcgctggcgc cgcaactgga
     2701 ctggtggcgc tcacgcctcg aaggcgctcc ttcgctggag ttgcccaccg accatgcacg
     2761 ccccgcggtc cgtagcggta agggcgcctc gtacttcttc acgctgtcct cggagcaagt
     2821 cgcgggcctg gagcgcgtag cctcggccca caacgccacg ctgtacatgg tgttgatggc
     2881 gggctggcag gcgctgctcg cgcgctactc cgggcagacg gacttctgcg tgggcacgtc
     2941 ggtggcccat cgcacccggc ctgagctcga agggctcatt ggcttcttcg tcaacacgct
     3001 ggcgctgcgc gcgaacgtgg atggcgatcc gcgtttcgat gacctgctgg cgcgagtccg
     3061 tgaggagtcc ctggcggcct tcgcgaacca ggacgttccc ttcgaccggc tggtggaggt
     3121 gctgggcggc cagcgcgacc tgtcgcgcac tccactgttc caggccgcct tcgttctcca
     3181 gaacgccccc atgcagccgc ccacgctgcc gggcatggtc gtcgacgtgc tgcacaccgg
     3241 cacggacacg gcccggttcg atgtgaccgc cctgctggtg gagcgtggcg ggcggctgga
     3301 gggcgagctc gagtacagcc tcgacctgtt caccccggag accgcgcgcc gcatggtgga
     3361 gcacttccag cggctgctcc gcggcgtcgt ggaggacgcc tcacgccgca tcagcgcggt
     3421 gccactgtgg agcgaggccg aacgccacga agtgctcgtg gcctggaacg acacggctgc
     3481 gccctatccc gctgacacga ccgtccatca gtgcttcacg gagcaggcgc tgaggactcc
     3541 gcaggccatc gccgtcgagc atgagggccg ctcgctcacg tatgcggagc tggatgcgcg
     3601 ttccaaccag ctcgcgcacc acctgcgctc gttgggcctg ggcgccgaat cgcgcgtggg
     3661 cgtcttcctg caccggggcc tggacctgct ggtgggcctg ctgggcatcc tcaaggcggg
     3721 cggcgcctat gtgccgctgg acccgtcgta ccccgcgcag cggctggcct tcatggccga
     3781 ggactccggt gtcgccgcca tcctcaccga gtcggcgttg gaggacgagc tgcccgccgg
     3841 ttcgcagctc atcgtggtgc tggatgagga atgggcgcgg attgagcgcc agccgtcgac
     3901 gcccgtgacg ggcgggctcg tgagcccaga gcagctcgcg tacatcacct acacctccgg
     3961 ctcgacgggg atgcccaagg gcgtggccat tccgcaccgg ggcgtggtgc gcctgctcat
     4021 cggctctcgc ttcgtggact tggggccgtc ggaggtggtg ctgcaactgg cgcccctggc
     4081 cttcgacgcg tccactctgg agatttgggg cgcgctgctg cacggagcgc gcctggtgct
     4141 ctacccgcag cgcacgccgg acctggcgga gctggggcag gcgctggtgc ggcaccaggt
     4201 gtcggtgctc tggctaacgg cggcactctt cgagcagatg cagcagcacc agccggaggc
     4261 tttgggcacg gtgcgtcagc tgctcgctgg cggcgacgtg ttgccggcgc ctcgcgtccg
     4321 ggagcggctg gcgcagggcg tggggttggt aaacggctat ggccccacgg agggcaccac
     4381 cttcaccgcg tgccaccgga tggcgccggg cgacgcggtg ggtgactccg tctccattgg
     4441 acggcccatc gcgaacactc aggtgtacgt gctggactcg gagatgcagg cggtgcccgt
     4501 gggtgtcccg ggtgaggtgc tcatcggcgg tgacggcctg gcccgggggt acctgggcca
     4561 gcccgcgctg acggccgagc gcttcgtgcc caatcccttc gggtctccgg gggcccggtt
     4621 gtaccgctcg ggagaccgtg cgcgttggca ggcggacggc acgctccagt tcctgggccg
     4681 cgtggacttc caggtgaagc tgcgcggctt ccgcatcgag ctgggtgaag tcgaggccgc
     4741 gctgcgcaac cactccgcgg tggagacggc gattgccgtg gtgcgcgagg acatcccggg
     4801 ggaccggcgg ctggtggcct acgtgacacc ggagaatgtg gacaccgcgt ccgtccggga
     4861 gcatctgcgc cagcggctcc ccgagtacat ggtgcccaac gccgtggtgg cgctgagcac
     4921 cctgcccctg tctccgaatg gcaaggtgga ccgtaaggcc cttccggctc cggacctcgt
     4981 cggtctgggg gctgaggact tcgtggcgcc ccgaacggag ctggagcagc aactggcggt
     5041 cctgttcagc gaggtgctcg gactggaacg cacgggcctg aacgacgact tcttcgaact
     5101 gggaggccac tcgctgctgg ccacccaggt cgtgacccgg ctgcgcgccc agcttggcgt
     5161 ggacctgccg ctgcgcacct tcttcgaggc ccccaccgtg gcgcgcctcg ccgcgcgcct
     5221 ggagtcggcg ccgcgaacca gcactttgct tcccttggag cccctgcccc ggccggccca
     5281 aggcgaggcg accttcgacg tctcgttcgc gcagcagcgg ctctggttca tcgagcaact
     5341 gcatcccgga cagttcacct acaacgtgcc cgcggcattg cagctgaagg ggcggttgga
     5401 cgaggaggcg ttgcggcgca ccttcctgga agtggtccgc cgtcacgaag cggtgcgcac
     5461 caccttcgtc atgcgcgagg gtcaaccggc ccagcgcatc cacccggcgc ccgccgagtg
     5521 gccactgccc gtcgaggact tgagcggctt ggagcccgag gcccgtgacg cggccgcgca
     5581 ggcccgcatg gtcgaagagg cccaccgcgc ctttgacttg gagaaggggc cgctactgcg
     5641 cacggtgctg ctgcgcacgg ggccggacgt gcatgtgctg ctgctgagca tgcaccacat
     5701 catctcggac ggctggtcca tgggcgtgct ggtgcgggaa gtggccgcgc tctatgaatc
     5761 gctgtcgcag ggccgtgacg ccgtgctgcc agtgctgacc gtgcagtacg cggactacgc
     5821 cgcatggcag cgacgtgtgc tggaaggccc ggcgctgacg ccgcagttgg actggtggcg
     5881 ctcgcggctc gaaggcgctc ccacgttgga gttgcccacc gaccacccgc gcccggcggt
     5941 gcgcacgttg cgcggggcca cgcatacgtt cacgctgccg ccttccctgg tggctgggct
     6001 ggagcgcgta gcgtcggccc acaacgccac gttgtacatg gtgctgatgg cgggctggca
     6061 ggcgctgctc gctcgctact ccgggcagac ggacttctgc gtgggcacgc cggtggccca
     6121 tcgctcccgg cccgagctcg aagggctcat cggcttcttc gtcaacaccc tggcgctgcg
     6181 cgcgaacgtg gacggcgatc cccgtttcga ggacctgctg gcgcgagtcc gcgaggaatc
     6241 cctggcggcc ttcgcgaacc aggacgttcc cttcgaccgg ctggtggagg tgatgggtgg
     6301 ccagcgcgac ctgtcgcgta cccccttgtt ccaggccgcc ttcgtcctcc agaacgcgcc
     6361 catgcagccg cccacgctgc cgggcctggt tgtcgacgtg ctgcgcacgg gcacggacac
     6421 ggcccggttc gatgtgtctg cgttgctggt cgagcgcggc gggcgcctgg aaggtgagct
     6481 cgagtacagc ctcgacctgt tcactccgga gaccgcgcgc cgcatcgtgg agcatttcca
     6541 gcggctgctc gaaggtgtcg tggaggacgc ttcacgccgc atcagcgcgg tgccgctgtg
     6601 gagcgaggcc gagcgccacg aagtgctcgt ggcctggaac gacacggctg cgccctaccc
     6661 cgccgacacc actgttcatc agcgcttcat ggagcaggcc cggcgcacgc cggagcgtgt
     6721 cgcggtgacc ttcgagggcc gttcgctcac ctacgcggag ctggacgctc gttccaacca
     6781 gttggcccgg cacctcgtgt ccttgggact ggggccggag gcccgcattg gcgtgtgcgc
     6841 gtcgcgcggg ttggagttgg tcatcggggt gctgggtgca ctcaaggccg gtggctgcta
     6901 cgtgccgttg gacccgtcct ggcccgtcaa gcgcctggag cacgcgacct cgacggcgcg
     6961 cctgtccgcg gtgttgacgt ggcagtcgct gttgccctcc ctcgaggacg gtccgtggca
     7021 cgtcgtggcg ctggacgcgg atgcggcgga catcgcccgt cagtccccgg aggccgtgca
     7081 ggttcccgtg ttcccagagg gactggcgtt cgccaccttc acctcggggt ccacgggaac
     7141 gcccaagggc gtggccgtgc cacatcgggg cttgctgcgg ctgagcgagg gctcccgctt
     7201 cctgacccag gcgcccgagg aagtcaccct tcagctcgcg cctgtggcct tcgacgtctc
     7261 cagcatcgag ctgtggggca cgctgctgca cggcggcaag ctcgtcgtgt acccgcccgg
     7321 gacgcccgag ccggacgcgg tggcccggct catcgtcgag cacaaggtgt cgtggctcgt
     7381 cctggcgacg tcactcttcg atctgttgca gcagcaccag cccgaggtcc tggcgcgagt
     7441 gcccaacctg ctgatgggcg gcgaagcgat gccagccccc cgtgcgcggg agcggttggc
     7501 gcggggtggt gccctgacca acggctacgg gcccaccgaa tgcagcacca tggccacccg
     7561 gcatacactg tcgcctgggg actccgtggg ccgctccgtc cccattggcc ggcccatcga
     7621 caacaccgag gtctatgtcc tcgacccggc actgcgtccc gtgcccgtgg gcgtgccggg
     7681 tgagctgtgc ctgggaggac cgggcctcgc gcgcggctac ctgaaccgcc cggacctcac
     7741 ggccgagcgc ttcgtgcctc acccgttcag cgccgcccct ggagcccggc tctaccgcac
     7801 gggtgaccgc gtccgctgga gcccggacgg cgtgctggag ttcctgggcc ggttggatca
     7861 ccaggtgaag gtgcgcggct tccgcatcga gctgggtgaa atcgaagccg tgctgcgcgc
     7921 gcatccttct gtcgtcgagg ccacggccgt cgtgcgcgag gacgcctccg gcagcaatcg
     7981 cgtggtggcg tatgtcgttc ccccgcaggc ggatgtggcg ccgctgcgcg agtacctgca
     8041 ccagcatctg ccggactaca tggtcccgtc cgcgttcgtc ggactggacg ccttcccgtt
     8101 gacgccgaat ggcaaggtgg accgcaaggc cctgccggcc ccggacctcg gtctgggagc
     8161 ggcggactac gtggagcctc gaacggagct ggagcagcaa ctggcggccc tgttccgcga
     8221 ggcgcttggc ctggaacgcg tgggcctgaa cgacgacttc ttcctcatgg ggggccactc
     8281 gctgctggcc acccaggttg tgacgcggct gcgcgcgcag ctcggcgtgg acctgccgct
     8341 gcgcaccttc ttcgaggccc ccaccgtggc gcgcctcgcc gcgcgcctgg agtcggcgcc
     8401 gcggaccggc accttgcttc ccttggagtc cctgccccgg ccggcccagg gcgaggcgac
     8461 cttcgatgtc tcgttcgctc agcgccgctt gtggttcatt gagcaactgc atcccggaca
     8521 ggtcacctac aacatgcccg cggccttgcg gctgacggga cggttggacg aggaggccct
     8581 gcggcgcacc ttcctggaag tggtccgccg tcacgaagcg gtgcgcacca ccttcgtgac
     8641 gcgcgaaggt caaccggtcc agcgcatcca cccggcgccc gccgaatggc cactgcccgt
     8701 cgaggacttg agcggcttgg agcccgacgc tcgtgacgcg gccgtgcagg tccgcatcgc
     8761 cgaagaggct caccacgcct tcgatttgaa gcagggcccg ctgctgcgca cggtgctgct
     8821 gcgcacgggg ccggacgtgc atgtgctgct gttgtgcatg caccacatca tctcggacgg
     8881 ctggtccatg ggcgtgctgg tgcgggaagt ggccgcgctc tatgaggcgc tgtcgcaggg
     8941 gcgtgagtcc ccgttgccag cgctgacggt gcagtacgcg gactacgccg tgtggcagcg
     9001 gcgcgtactg gagggcccgg cgctggcgcc gcaactggcc tggtggcgct cgcggctcga
     9061 aggcgttccc acgttggagc tgcccaccga ccacgtgcgt cccgcggtca gtagcgccaa
     9121 gggcacttcg tacttcttct cgctgtccgc ggagctggtg gcgggtctgg aacgcgtggg
     9181 ctcggcccac aacgccacgc tgtacatggt gctgatggcg gggtggcagg cgctgctcgc
     9241 gcgctactcc gggcagacgg acttctgcgt gggcacgtcg gtggcccatc gcacgcggcc
     9301 ggaactcgac gggctcattg gcttcttcgt caacaccctg gcgctgcgct gccggttgaa
     9361 cggcaatccg accttcgccg agctcgtggt ccgtgtccgc gacgaggccc tgggcgcctt
     9421 cgcccatcag gacgtgccgt tcgagcagct cgtggatgcc gtgggcggtg agcgcgacct
     9481 gtcccggacg ccgctgttcc agacgctctt cgtgctcctg aactcggacc tcatccaagc
     9541 gccgtcgctt ccggggctcc acgtcgacgt gttgccgagc gcgacggaca cggcccggta
     9601 tgacttgacg ctcgcgatga gggcgcgcgg cggcgagttg gaaggccagc tggaatacag
     9661 tcaggacctc ttcaccgcgg acaccgccag gcgaatggtg gagcaccttc gagtgcttct
     9721 gtcggcggtg gcggatgggg ccggttcgca gcggctcagt gcgctgacca tgatggaggc
     9781 ccaggagcgc cagcaggtgc tctcgacctg gaatgccacc caggccgcct atccggtgga
     9841 cgcgaccgtg ccttcgctct tcacggagca ggcactgagg actccacagg ccatcgccgt
     9901 cgagcatgag ggccgcacgc tcacgtatgc ggagctggat gcgcgttcca accaactcgc
     9961 gcaccacctg cgctcgctgg gcctgggcgc cgaatcgcgc gtgggcgtct tcctgcaccg
    10021 gggcctggac ttgctggtgg gcctgctggg catcctcaag gcgggcggcg cctacgtgcc
    10081 gctggacgcg tcgtaccccg cgcagcggct ggccttcatg gccgaggact cgggtgtcgc
    10141 cgccatcctc accgagtcgt cgttggagga cgagctgccc gccggttcgc agctcatcgt
    10201 ggtgctggat gaggaatggg cgcggattga gcgccagccg tcgacgcccg tgacg
//
