LOCUS       NZ_FNAJ01000013        10846 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Myxococcus virescens strain DSM 2260, whole genome shotgun sequence.
ACCESSION   NZ_FNAJ01000013
VERSION     NZ_FNAJ01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Myxococcus virescens
  ORGANISM  Myxococcus virescens
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101905.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 02:08:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,594
            CDSs (total)                      :: 7,524
            Genes (coding)                    :: 7,456
            CDSs (with protein)               :: 7,456
            Genes (RNA)                       :: 70
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 15 of 68
            Pseudo Genes (incomplete)         :: 65 of 68
            Pseudo Genes (internal stop)      :: 7 of 68
            Pseudo Genes (multiple problems)  :: 17 of 68
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:03:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 182167
            Orig. end                         :: 193013
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNAJ01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(319..334)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            332..1456
                     /locus_tag="BLU09_RS29135"
                     /old_locus_tag="SAMN04488504_113130"
     CDS             332..1456
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554930.1"
                     /locus_tag="BLU09_RS29135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113130"
                     /product="carboxypeptidase regulatory-like
                     domain-containing protein"
                     /protein_id="WP_090493190.1"
                     /transl_table=11
                     /translation="MRSTIHIAVATLVACCAAGCGNLENAPFRVGTVHGQLTESDPAVA
                     MVSLVGQPGVSSPVDADGRFTLEDVPTGMAELFIIATTEKAARVQVRVLGGQSVQVQPV
                     APTSAGFLDLHVKTTNGFRLTAAEASVEGTPFQRLLLDAKGRLRVGPLPDGCYTVTVTA
                     LGFPATQVQDCAGPGEKKELKVDLVVDESLLEQGCQEIGCEEGLVCAPNKKCLECFGNS
                     HCGEGLTCKGNRCEGPGPLCAPCTGDWQCAAGTYCEVLPEGSAACATRCGGDDDAPPSV
                     QALPDDVGSAQCAPGFTCQSGRCLPDAANFAGCHALRRMDAPCTDDASCHELGLLEGRC
                     VSGACTAPCATDLDCPGSRRCVDSSAGRVCQAGT"
     gene            1461..4244
                     /locus_tag="BLU09_RS29140"
                     /old_locus_tag="SAMN04488504_113131"
     CDS             1461..4244
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554931.1"
                     /locus_tag="BLU09_RS29140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113131"
                     /product="PKD domain-containing protein"
                     /protein_id="WP_090493193.1"
                     /transl_table=11
                     /translation="MASQGPPRLRLVLVPLVAATLWGCEPAPRPPPTTHNTPPRLEVSP
                     TLDIIPLRVGQAVEFAATVEDAEEGAALGANVLWVSSVEGQRARGARATLAFHEPGAQR
                     LTASVVDAGGLAASASLHLNVLARGAPVATVLRPAPGSTFNLGEELGLECMALTERGVR
                     LQGRAVQWTSALSGPLPAGDVVRATLSVAGEDTLRCTAVDSATKVSATADVRVTVRATR
                     APSVRILRPEPTEIFVKQGEAPPHGASVRFAATAQDFHAEGGAGNLDDAVEWSLAPSGH
                     PLGRGPALTHAFTTPGVYTVRARVVDGRGNTASDSVRVRLVTNLPPRCELELPTTENPR
                     VLVGVPSQLRARCVDPETEQPAEPIWTTSAEPTPLGTGEAVSAVLSVAGAQVLAACAVD
                     PEDTALRGCVERPVRAIINTPPTGCAIQAPLPNAVVNAGVPLALTGLASDAEDARTGLR
                     YTWVSSRDGALAQGPSTHTVRLSTPGPHVLTLTATDPWGLACAAAVAVTVNGAPDVRVE
                     SVMQGLLDCGRGPCQEGQPVVLTGFARPAVPQGHIAELAWLDNLAGSLVAVALPLPTAT
                     LAFPLAGRHTTVLAATDQDGPVSRAATSFTVLPLGRARLMEDVPDAQRPVVALALTPDG
                     LRYADGTSPRVYAERASTTVLDVNAPALSLHAFQGGNVLFVGTDGGGVLRCVQRTCTRH
                     TGAMLGATGAAVTAVAAWESPDVLLLGTRRGLVLTRASDPASGGRAGTVGGRRLLEGRE
                     VRQLAISPDSSPERVTAWAATSGGLAEITFWADDDFEPGLAEVSVRLHAPPAIPDDDVL
                     SVAVGPEGQVFAGTRKGFSALGQPGPALRDAPWRLQDEEIRTLLFERQAVDARTRDILW
                     AGTKNGLVRYDVSADIATHFGTEEGLPDPDVSALMVAPGGPRYVGTARGLVTYPWH"
     gene            complement(4267..5004)
                     /locus_tag="BLU09_RS29145"
                     /old_locus_tag="SAMN04488504_113132"
     CDS             complement(4267..5004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941507.1"
                     /locus_tag="BLU09_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113132"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_090493195.1"
                     /transl_table=11
                     /translation="MKPSLRDFFDSMGDYLAEPGPESLAALYARHPGWEAPRERVSLYG
                     GFVLGHVRSALDKVFPLTRQALGQDAWDGLVVAFTRTRPARHHELNHLCEGFPAFLADA
                     AASRGLAPFVPALARFEWTDFAVFASLEPSPERVERLTANPTLVVLEHDFHLCAYVRAR
                     GAATSPEAGAELALLWRHPEQLKTLYMAATPPALLVLKMAVEGLALADVVAATGMAEAD
                     LRATVTRFGRDGLVLLPDDSDGG"
     gene            complement(5001..5846)
                     /locus_tag="BLU09_RS29150"
                     /old_locus_tag="SAMN04488504_113133"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554933.1"
                     /locus_tag="BLU09_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113133"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_090493197.1"
                     /sec_met_domain="DUF692 (E-value: 1.6e-95, bitscore: 312.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTYAQRHGLKPLGAGIGLRRSFYAELPRTERTLDWVEIIPENFL
                     SLGGRSQRALDACAERWPVLPHGVGLNIGGPDALDDDYVRGLAALVKRVEAPFFSDHLC
                     FSRLDGVYLHDLLPLPFSEAAVEHVVPRVREVMDRVGRPFLLENPSYYARMPGGTLREA
                     DFLRRVVEQADCGLLLDVNNVYVNARNHGYDARAFVDALPLERVVQIHLAGHTCYPDVI
                     VDTHGDRVCDDVWSLYRYVLSRTGPVATLIEWDQDLPSLDAVLDEADIARASLREVAGP
                     "
     gene            complement(5961..6206)
                     /locus_tag="BLU09_RS29155"
                     /old_locus_tag="SAMN04488504_113134"
     CDS             complement(5961..6206)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941509.1"
                     /locus_tag="BLU09_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113134"
                     /product="hypothetical protein"
                     /protein_id="WP_090493199.1"
                     /transl_table=11
                     /translation="MNVKALAAVVGTLSLAALATGCATKKSAEMEPATAEETGAESSGA
                     TESQEAAPAATEEKGAEGSCGAGSCGSGSCGGQKKE"
     gene            complement(6265..7680)
                     /locus_tag="BLU09_RS29160"
                     /old_locus_tag="SAMN04488504_113135"
     CDS             complement(6265..7680)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637554.1"
                     /locus_tag="BLU09_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113135"
                     /product="hypothetical protein"
                     /protein_id="WP_244172102.1"
                     /transl_table=11
                     /translation="MRARAAAVILLGLSLMSCQAPLRHHPREDVAALRYNLTYVREPEH
                     AVDVEVVLVRGTPREFLFSQPGAVTTVSAHREDGGVQTLPVQEGRVVLPRGTRFLRYRY
                     ALDASIRERGPDFFQGSGDGDARHVAGRAYLIRPRVVKPGLRVELSLVGTDALLPWQPG
                     ENGVYRLRGEDLVDSGFHGFGGRRCQVRLPDAVLDVAILGHFTHLSDAAVCTWLGKAAE
                     EVRTVRRAFPHPRITVRVIPAPGHHGPSVFGMVRWSSPPSISISVGQEARPEDFARDWV
                     AVHEMLHLTHPVFVPRVPWLSEGLATYYTEVARARSGRQDSRRAWEELLGGFARGLEGN
                     DTRTMQEAVSQDSFSLAVYWTGALFALHLDVELRRITGNMRGLDDVLELLAARGSSSTF
                     GAFGAAVDAVAGQPLFNALLERHLPRPAFAEQAGLLEALGVQEGPNGVSLVPARDSLLR
                     DSVVGRRSHGETP"
     misc_feature    complement(7839..7852)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.83"
                     /tool="antismash"
     misc_feature    complement(8046..8061)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.56"
                     /tool="antismash"
     misc_feature    complement(8059..8073)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    complement(8079..8093)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.61"
                     /tool="antismash"
     gene            8152..9771
                     /locus_tag="BLU09_RS29165"
                     /old_locus_tag="SAMN04488504_113136"
     CDS             8152..9771
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554936.1"
                     /locus_tag="BLU09_RS29165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113136"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_090493203.1"
                     /transl_table=11
                     /translation="MNDNALNANVGLKLRGLRLARNIKQADAAKDLGVSPAYLNLIEKG
                     KRVMPFPLLWKALRYFDQDPEQFMSTLGEGRVDEALAKLLDEPLLKSLDIDPESLQSLS
                     AEPKLAGTVAALFNLYKNTRTQLENVLAQLNVEERTRTQGGPGNGTSPGVRFDYSPFDE
                     VSDFLEKHRNYFPELEEQADALRRDVRLERQITSGQLIRLLEERFGYRVLFDDPSPSGS
                     SVVRRLDPEERTLTLSPFLTEQPLKFQIAASIGLLVMDREKLLERVLDAGRMRHGETQR
                     LIKVNLANYFAGALMLPYGDFFKEVQRTRYDVELLSSIFGSTYETVAHRLCNLSDPKRP
                     GLPFHFLRADIAGNISKRYSGTGIRFASGGGSCAKWAVHLAFLNPSQLTRQYSIMPDGT
                     AYFCFAKVQLQPIEGSIVKGTAYSIGLGTHAENAKYLAYGLPTTDLRKDAIPSGISCRF
                     CERTDCNQRAAASYRFAFAFDEYTKKDCFFSPILVHEKADKVEKDRHPSAHSLAVAANG
                     TDGSEKDDSLDKTSRRRKGGDA"
     gene            9780..10655
                     /locus_tag="BLU09_RS29170"
                     /old_locus_tag="SAMN04488504_113137"
     CDS             9780..10655
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554937.1"
                     /locus_tag="BLU09_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN04488504_113137"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_090493205.1"
                     /transl_table=11
                     /translation="MHHPPEDTQRTHILDAIQKQKNALAPLRITGSPTEVGQGLVNLAE
                     LHGLLEDHAASRQFYEEALEKFQEAKYKPGQAQALMGLGVVKANFEDHRGAIEQIARAA
                     MLFNESKDREGEALARACIGESLRSLGQPEAAEEKYQEALILLRQTRNTERVARLLIDI
                     GDIRMEKGDYEPARKRFLEAVPLLEQGDDPEALALGHLLLGESEGLLGNHEGARPHLLR
                     AVELYQEVHDHAYEARARWDLGLSCYYQQDFAAARKQFETLIPLYGDLGQTGEVAKVQN
                     ILAHFTARGV"
ORIGIN
        1 cgccgggcag cgaggtgccc ttccgctaca ccaccctctc cgcgggagtg gcccttccct
       61 acctgtggcg ctgggagcgg ctgacgttgt tcgcggggcc gcgtgtggcc ggcctgcacc
      121 tcaggcggtc ctttgacata gaggccgccg tcaacgggca gcggttcttt accgtcagcc
      181 ccggcgtggt gggcggcatc gtgtggcggg tgggtgagcg gctggagctg atgacacagg
      241 cccagttcat gctgacgtat gtcgttgtgg atgggcaggg gcaggccgtg ggtttcacgg
      301 gtggctgggc cggcgcggga tatcgattct gatgcgctcg acgattcaca tcgcggtagc
      361 caccctcgtg gcctgctgcg ccgcgggctg cggcaacctg gagaacgccc ccttccgggt
      421 gggcaccgtg catgggcagc tcacggagag cgaccctgcg gtagccatgg tgtcgctggt
      481 gggccaaccc ggcgtgagca gccctgtcga cgcggacggg cgcttcaccc tggaagacgt
      541 ccccacgggg atggcggagc tcttcatcat cgccacgacc gaaaaggccg cccgcgtcca
      601 ggtgcgggta ttgggaggcc agtccgtcca ggtgcaaccg gtggcgccca cgtccgcggg
      661 cttcctcgac ttgcacgtga agacgaccaa cggcttccgg ctgaccgcgg cggaggcgtc
      721 cgtggagggc acgcccttcc agcggctgct gctggacgcg aaggggcggc tgcgcgtggg
      781 gccccttccg gacggctgct acacggtgac ggtgacggcc ctgggctttc cagccaccca
      841 ggtgcaggac tgcgcgggcc cgggcgagaa gaaggagctc aaggtcgacc tggtggtgga
      901 cgagtcgctc ctcgaacagg gctgccaaga gattggctgc gaggaaggcc tggtgtgcgc
      961 gccgaacaag aagtgcctgg agtgcttcgg caactcgcac tgcggcgagg gattgacctg
     1021 caagggcaac cgctgcgagg gccccggtcc cctgtgcgcg ccctgcacgg gcgactggca
     1081 atgcgccgct gggacgtact gcgaggtgct ccccgaagga agcgccgcgt gcgccacccg
     1141 gtgcggcggc gacgatgacg ctcccccctc cgtccaggcg ctgccggacg acgttgggtc
     1201 ggcccagtgc gcgccgggct tcacctgcca gtccgggcgg tgcctgcccg atgccgcgaa
     1261 cttcgcgggc tgccatgccc tgcggcggat ggacgcgccc tgcaccgacg acgcgagctg
     1321 ccacgaactg ggactgctcg aagggcgctg tgtcagcggg gcctgcacgg cgccctgcgc
     1381 aacggacctc gactgcccgg gcagccggcg gtgcgtggat tcatcggcgg gccgcgtctg
     1441 ccaggccggg acgtgacccc gtggcgagcc aaggcccccc tcggctccgc ctcgtgctgg
     1501 tcccgctggt cgccgccacg ttgtggggct gtgagccagc cccccgccct ccgccaacga
     1561 ctcacaacac gcctccccgg ctcgaagtca gccccaccct ggacatcatc ccgctgcgcg
     1621 tgggccaggc cgtggagttc gcggccaccg tcgaggatgc ggaggaaggc gcggcgttgg
     1681 gcgccaacgt gctgtgggtg tcctccgtcg aagggcaacg ggcccgcggc gcgcgcgcca
     1741 cgctcgcctt ccacgaaccc ggagcgcagc ggctgaccgc ctcggtggtg gacgccggtg
     1801 gactggccgc gagcgcgtca ctccacctga acgtcctcgc gcggggtgct cccgtggcca
     1861 ccgtgctgcg ccccgcgccg ggcagcacct tcaacctcgg cgaggagctg ggcctggagt
     1921 gcatggcgtt gacggagcgt ggcgtgcggc tccaggggcg cgcggtgcag tggacgtccg
     1981 cgctgtccgg gccgctgcct gccggcgacg tggttcgggc gaccttgtcc gtggccggcg
     2041 aggacaccct ccgctgcacc gcggtggact ccgccacgaa ggtctccgcc accgccgacg
     2101 tgcgcgtcac cgtccgcgcc acgcgggccc ccagcgtgcg catcctccgg cccgagccca
     2161 cggagatctt cgtgaagcaa ggcgaggccc cgccccacgg cgcctccgtc cgcttcgcgg
     2221 ccaccgccca ggacttccac gccgagggag gcgcgggcaa cctcgacgac gcggtggagt
     2281 ggagcctggc cccctcgggg catccgctgg gccgaggccc ggccctgacc cacgccttca
     2341 ccacgcccgg cgtctacacg gtgagggcgc gggtggtgga tgggcgcggc aacaccgcct
     2401 cggacagcgt gcgggtgcgg ctggtcacca accttccgcc ccggtgcgag ctggagctcc
     2461 ccacgaccga gaatccacgc gtgctcgtgg gcgtccccag ccagctgcgg gcccgctgcg
     2521 tggacccgga gacggagcaa ccggcggagc ccatctggac taccagcgcc gagcccacgc
     2581 ccctgggcac gggtgaagcc gtcagcgccg tgctgtccgt ggccggtgcg caggtgttgg
     2641 ccgcgtgcgc cgtggaccca gaggacaccg cgttgcgcgg ctgcgtggaa cgaccggtgc
     2701 gcgccatcat caacacgccg cccacgggct gcgccatcca ggcaccgctt ccgaacgcgg
     2761 tggtgaacgc gggtgtgccg ctggcgctca cgggtttggc gtcggacgcg gaggatgcgc
     2821 ggacgggcct gcgctacacg tgggtgtcct cgcgggacgg cgcactggcc cagggtccga
     2881 gcacgcacac cgtccgcctg tccacgcccg gcccccacgt gctgacgctc accgcgacgg
     2941 acccgtgggg actggcctgc gcggcggccg tggcagtcac cgtgaacggc gcgcccgacg
     3001 tgcgggtgga gagcgtgatg caaggactgc tggattgcgg cagaggccca tgccaggagg
     3061 ggcaacccgt ggtcctcacc ggcttcgcga ggcccgcggt cccccagggc cacatcgcgg
     3121 agctggcgtg gctggacaac ctggcgggga gcctcgtggc ggtcgcgctg ccgctgccca
     3181 ccgccaccct cgccttcccc ctcgccggtc gccatacgac ggtgctggcc gccaccgacc
     3241 aggacggccc cgtgagccgc gcggcgacgt ccttcacggt gctgccgctg ggacgcgcgc
     3301 ggttgatgga ggacgtcccg gacgcgcagc ggcccgtggt ggccctggcg ctcaccccgg
     3361 acgggctccg ctacgcggat ggcacttctc cccgggtgta tgcggagcgc gcgtccacga
     3421 cggtgctgga cgtgaacgcc ccggccctgt cgctccatgc gtttcaaggt ggcaacgtgc
     3481 tcttcgtggg cactgacggc ggcggcgtgc tccggtgcgt ccagcgcacc tgcacccggc
     3541 acacgggcgc catgctgggg gccacgggcg cggcggtgac cgcggtggcc gcatgggaat
     3601 ccccggacgt gctgctgctg ggcacccgcc ggggcctggt cctcacacgc gcgagcgacc
     3661 ccgcctccgg aggacgcgcg ggcaccgtgg gaggccgccg cctgctggag ggacgcgagg
     3721 tgcgccagct cgccatctcc ccggactcca gcccggaacg cgtgacggcc tgggcggcca
     3781 cgtcgggcgg cctcgcggaa atcaccttct gggcggacga cgacttcgag cccgggctcg
     3841 ccgaagtctc ggtgcggctt cacgctccgc cggccatccc cgatgacgac gtcctctccg
     3901 tggccgtggg gccggagggc caggtgttcg ccggcacgag gaagggcttc agcgcgctgg
     3961 gacaacccgg tcccgcgctg cgcgacgcgc cctggagact gcaggacgag gagattcgca
     4021 cgctcctctt cgaacggcag gccgtggacg cgcgcacccg ggacatcctc tgggccggca
     4081 cgaagaacgg gctggtgcgt tatgacgtgt cagcagacat cgccacccac ttcggaacgg
     4141 aagagggctt gccggacccg gacgtgagcg ccctgatggt ggctccggga ggaccgcgct
     4201 acgtgggcac ggcgcggggc ctggtgacgt acccctggca ctgagcgccc agacagcgcg
     4261 ggcacttcat cccccgtcgc tgtcatccgg gaggagcacc agtccgtcgc ggccgaagcg
     4321 cgtcaccgtc gcgcgcaggt cggcttccgc catgcccgtg gccgccacca cgtccgccag
     4381 ggccagccct tccaccgcca tcttcaacac cagcagtgcc ggtggcgtgg cggccatgta
     4441 gagcgtcttc aactgctccg ggtggcgcca cagcagcgcc agctccgcgc ctgcctccgg
     4501 tgacgtcgcg gcgcctcggg cccgcacgta cgcgcagagg tggaagtcgt gctccagcac
     4561 caccagggtg ggattggccg tcagccgctc cacgcgctcg ggcgatggct ccagggacgc
     4621 gaacaccgcg aagtcggtcc actcgaagcg ggccagtgcg ggcacgaagg gcgccagccc
     4681 ccgcgaggcc gccgcgtccg cgaggaacgc gggaaagcct tcacacaggt ggttgagctc
     4741 atggtgccga gccggccgtg tccgcgtgaa ggccaccacc aggccgtccc atgcgtcctg
     4801 ccccagggcc tggcgcgtca gcggaaagac cttgtccagc gcggagcgca catggccgag
     4861 cacgaagccg ccgtagagcg acacccgctc gcgcggcgcc tcccaccccg ggtgcctcgc
     4921 gtacagcgcg gccagcgact ccgggccggg ctcggcgagg tagtccccca tgctgtcgaa
     4981 gaagtcgcgc agggacggct tcatgggccg gcgacctccc gcagcgatgc gcgcgcaatg
     5041 tccgcctcgt ccaacaccgc gtccagggaa ggaaggtcct ggtcccactc gatgagcgtc
     5101 gccaccggcc cggtgcgcga aagcacgtag cggtagagcg accacacgtc gtcgcagacg
     5161 cggtcgccat gcgtgtcgac gatgacgtcc gggtagcagg tgtggccggc caggtgaatc
     5221 tgcaccacgc gctccagcgg cagggcatcc acgaaggccc gcgcgtcgta gccatggttg
     5281 cgcgcgttga cgtagacgtt gttcacgtcc agcagcagcc cacagtccgc ctgctccacg
     5341 acgcggcgga ggaagtccgc ttcccgcaac gtgccgccgg gcatccgcgc gtagtagctg
     5401 ggattctcca gcaggaaggg acggcccacc cggtccatca cctcgcgcac gcggggcacc
     5461 acgtgctcga cagcggcctc gctgaacggc agcggcagca agtcgtgcag gtacacaccg
     5521 tccagccgcg aaaagcagag gtggtcggag aagaagggcg cctccacccg cttcaccagc
     5581 gccgccagtc cccggacata gtcgtcgtcc agcgcgtccg ggccgccgat gttcaacccc
     5641 acgccgtggg gcaacacggg ccaccgctcc gcgcatgcgt ccaacgcgcg ctgcgagcgc
     5701 ccacccaatg acaggaagtt ctccgggatg atctccaccc agtcgagcgt ccgttcggtg
     5761 cgcggcagct ccgcatagaa gctcctgcgc agcccgatgc ccgcgcccag cggcttcagc
     5821 ccatgtcgct gtgcgtacgt caccacggca gaagccctct cgaaacatgg gaaacaaccc
     5881 gggcggcggt ggtgctgctc aaccgcccgg cagcgagggc ccggccttca ccaggccctc
     5941 gggacttccg tccggcggaa ctactccttc ttctggccgc cgcaggagcc ggagccgcac
     6001 gagccggcgc cacagcttcc ctcggcgccc ttctcctcgg tcgcggccgg agcggcctcc
     6061 tgcgactccg tggcgccgct gctctccgcg ccagtctctt cggccgtggc gggctccatc
     6121 tccgccgact tcttggtcgc acaacccgtg gccagcgcgg ccagggacag ggtgccgaca
     6181 accgctgcaa gcgccttgac gttcatggat gagacttcct ttcggtactg cgtggggggt
     6241 gttgtgtgga ggtcgcggtt gcattcaggg tgtttcgccg tggctgcgcc gaccgaccac
     6301 cgaatcacgc aacagactgt ctcgagcagg taccagcgag acgccgttgg gtccttcctg
     6361 gacacccagc gcttctagca gaccggcctg ctccgcaaaa gcaggccgcg gcaagtgccg
     6421 ctccagcaga gcattgaaca gcggctgtcc cgcgacggca tccaccgcgg caccgaatgc
     6481 cccgaaggtc gaggaactgc cgcgagccgc gagcaactcc agcacgtcat ccagcccgcg
     6541 catgtttcca gtgatacggc gcaattccac atccagatgc aacgcgaaga gcgctcccgt
     6601 ccaatagaca gcgagcgaga agctgtcttg agacacggcc tcctgcatgg ttcgcgtgtc
     6661 attgccctcg agcccccgag cgaagccgcc cagcagctcc tcccaggcgc gccgcgagtc
     6721 ctgccgtccg gagcgcgcac gcgcgacctc cgtgtagtag gtggccagcc cctccgacag
     6781 ccacggcacg cggggcacga agacaggatg ggtcaggtgc agcatctcgt ggacggccac
     6841 ccagtcccgc gcgaagtcct ccggccgcgc ctcctgcccc acgctgatgg agatgctggg
     6901 cggcgaactc cagcgcacca tgccgaagac gctgggcccg tggtgcccgg gcgcggggat
     6961 gacccgcacg gtgatgcgcg gatgcgggaa ggcgcgccgc acggtgcgga cctcctccgc
     7021 ggccttgccc aaccaggtgc agacggccgc gtcgctcagg tgcgtgaagt gtcccaggat
     7081 ggccacgtcc agcaccgcgt ccggcaggcg cacctggcac cggcggccgc cgaagccgtg
     7141 gaagcccgag tccaccaggt cctcgccgcg cagccggtac acgccattct ccccgggctg
     7201 ccacggcagc aatgcatcgg tgcccaccag cgacagctcc acgcggaggc ccggcttcac
     7261 cacccgcggc cggatgaggt aagcgcggcc cgcgacgtgc cgcgcatcgc cgtctccgga
     7321 gccctggaag aagtccgggc cgcgctcgcg aatggaggcg tccagcgcgt agcggtagcg
     7381 caagaagcgc gtcccccgtg gcagcacgac gcggccctcc tggacgggca atgtctggac
     7441 gcccccatcc tcccggtgcg cggacaccgt cgtcacggcg cccggctggc tgaagaggaa
     7501 ctcgcgcggc gtgcctcgca ccagcaccac ctccacgtcc accgcgtgct cgggctcgcg
     7561 cacgtaggtg aggttgtagc gcagcgccgc cacatcctcc ctggggtggt ggcgcagcgg
     7621 cgcctgacac gacatcaacg acaggccgag caggatgacg gcggcggctc gggcacgcat
     7681 gcgcagcggc gccctgctcc accttcgcgg ccctccatgc ccaccgtcca tacgcggcga
     7741 aggttcgccc atgacgcgcc ggaggtgaat cgccccctgg cagcgtgcgc cccgctcagc
     7801 cccacgttcg atcgcacccg agccccggac tgttcttgta aaccggcgtt tcttccttta
     7861 ccgcagcgcg tcccgcccat gccgcagtgc agcagtaaat gcttgacaag gcgctgtaga
     7921 gagcgcgacg acaggttccc cacacgccca aaagggctgt gatttcatga ggttcagggt
     7981 agaaggcacc ccggctccga ccgcggtcca gccggtccgt cgcagggccg acaggggtcc
     8041 tcgtggatga aaaggatcat tgcaaatcgg taaatcgatt tgcagagtgg gtaaagagcc
     8101 cgaggcgcgc gcggccattc gcgatcgccg gaggcgtcaa cgcacccggc catgaacgac
     8161 aacgcactga acgccaacgt gggcctgaag cttcggggac tgcgccttgc acggaacatc
     8221 aagcaggcgg acgcagccaa ggacctgggc gtttcccccg cgtacctgaa cctcatcgag
     8281 aagggtaagc gggtgatgcc cttccccctg ctctggaagg ccctgcgcta cttcgaccag
     8341 gaccccgagc agttcatgtc cacgctgggc gaaggccgcg tggacgaagc gctcgcgaag
     8401 ctgctggacg agccgctcct caagagcctc gacatcgacc cggagtcgct ccagtccctc
     8461 tccgcggagc cgaagctcgc gggcacggtg gcggcgctct tcaacctcta caagaacacc
     8521 cgcacgcagt tggagaacgt gctggcacag ctcaacgtcg aggagcgcac gcgcacccag
     8581 ggcggcccgg gcaacggcac ttcgcccggt gtgcgcttcg actactcgcc cttcgacgag
     8641 gtcagcgact tcctggagaa gcaccgcaac tacttcccgg agctggaaga gcaggcggac
     8701 gcgctgcgcc gcgacgtgcg cctggagcgg cagatcacca gcggtcagct catccggctc
     8761 ctggaggagc gcttcggcta ccgcgtcctc ttcgacgacc cgtccccctc cggctcatcc
     8821 gtggtgcggc ggttggaccc ggaggagcgg acgctgacgc tgtcgccctt cctcaccgaa
     8881 cagccgctga agttccagat tgccgcgtcc attggcctgc tggtgatgga ccgcgagaag
     8941 ctgctggagc gcgtgctgga cgcgggccgc atgcgccacg gcgagacgca gcggctcatc
     9001 aaggtgaacc tggccaacta cttcgccggc gcgctgatgc tgccctacgg ggacttcttc
     9061 aaggaggtcc agcgcacgcg ctacgacgtg gagctgctgt cgagcatctt cggctccacc
     9121 tacgagacgg tggcccaccg cctgtgcaac ctgtcggacc cgaagcgccc cgggcttccg
     9181 ttccacttcc tgcgcgcgga catcgccggc aacatctcca agcgctacag cggcaccggc
     9241 atccgcttcg cctctggcgg cggcagctgc gccaagtggg ccgtgcacct ggccttcctc
     9301 aacccgtccc agctgacgcg gcagtactcc atcatgccgg acggcaccgc ctatttctgc
     9361 ttcgccaagg tgcagctcca gccgattgag ggctccatcg tcaagggcac cgcgtactcc
     9421 atcggcctgg gcacccacgc ggagaacgcc aagtacctgg cctacggcct gcccacgacg
     9481 gacctgcgca aggacgccat tccgtccggc atctcctgcc gcttctgcga gcgcaccgac
     9541 tgcaaccagc gcgcggcggc cagctaccgt ttcgccttcg ccttcgacga gtacacgaag
     9601 aaggactgct tcttctcccc catcctcgtc cacgaaaagg ccgacaaggt ggagaaggac
     9661 cggcacccca gcgcccattc cctggccgtg gccgccaacg ggactgacgg gagcgagaag
     9721 gacgattcgt tggacaagac ctcccgccgc cgcaagggtg gcgacgcctg aggcccccca
     9781 tgcaccaccc gcccgaagac acccaacgca cccacatcct cgacgccatc cagaagcaga
     9841 agaacgcgct ggcgccgctg cgcatcaccg gctcgcccac cgaggtggga cagggtctgg
     9901 tgaacctggc cgagctgcac ggtctgctgg aggaccacgc cgccagccgg caattctacg
     9961 aagaggcgct cgagaagttc caagaggcca agtacaagcc cggccaggcg caggccctga
    10021 tggggctggg cgtggtgaag gcgaacttcg aggatcaccg cggcgccatc gagcagattg
    10081 cccgcgccgc catgctcttc aacgagtcca aggaccgtga gggcgaggcc ctggcccgcg
    10141 cctgcatcgg cgagtccctg cgctcgctgg gccagccaga ggccgccgag gagaaatacc
    10201 aggaggcgct catcctcctg cgccagacgc gaaacacgga gcgggtggcg cggctgctca
    10261 tcgacatcgg cgacatccgc atggagaagg gcgactacga gcccgcgcgc aagcgcttcc
    10321 tggaggccgt gccgctgctg gagcaaggtg atgatccgga ggcgctcgcg ctgggccacc
    10381 tgctgctggg cgagtccgag gggcttcttg gcaaccacga aggtgcgcgc ccgcacctgc
    10441 tccgcgcggt ggagctgtac caggaggtgc acgaccacgc gtatgaggcc cgcgcccgct
    10501 gggacttggg cctgtcctgc tactaccagc aggacttcgc ggcggcccgc aagcagttcg
    10561 agacgctgat tcccctctac ggggatctgg gtcagacggg cgaagtggcc aaggtccaga
    10621 acatcctggc ccacttcacc gcgcgcggcg tgtgagcgct cctccctgac accggggaga
    10681 gcgccgtcac acgcgctctt cctaggcttg gatgccggtg cccaccgcga tggcgagcag
    10741 ccccagcacg cccgcggcca tcaccatgta gcgccactca ccccgcaggc ccagcagcgt
    10801 gcccgccacc gcgagccgcg ccacgggcgt caccaacagc agtgac
//
