LOCUS       NZ_FMZZ01000034         6199 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinokineospora iranica strain IBRC-M 10403, whole genome shotgun
            sequence.
ACCESSION   NZ_FMZZ01000034
VERSION     NZ_FMZZ01000034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora iranica
  ORGANISM  Actinokineospora iranica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:26:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,202
            CDSs (total)                      :: 6,139
            Genes (coding)                    :: 6,038
            CDSs (with protein)               :: 6,038
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 25 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 7 of 103
            Pseudo Genes (multiple problems)  :: 18 of 103
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 6199
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMZZ01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..6155)
                     /locus_tag="BLS56_RS30255"
                     /old_locus_tag="SAMN05216174_1341"
     CDS             complement(<1..6155)
                     /NRPS_PKS="Domain: PCP (74-143). E-value: 5.9e-28. Score:
                     88.9. Matches aSDomain: nrpspksdomains_BLS56_RS30255_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (156-456). E-value:
                     2.2e-118. Score: 386.5. Matches aSDomain:
                     nrpspksdomains_BLS56_RS30255_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (624-1004). E-value:
                     1.8e-107. Score: 351.4. Matches aSDomain:
                     nrpspksdomains_BLS56_RS30255_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1098-1166). E-value: 2.5e-28.
                     Score: 90.1. Matches aSDomain:
                     nrpspksdomains_BLS56_RS30255_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1181-1472). E-value:
                     5.5e-107. Score: 349.1. Matches aSDomain:
                     nrpspksdomains_BLS56_RS30255_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1636-2013). E-value:
                     7.1e-96. Score: 313.2. Matches aSDomain:
                     nrpspksdomains_BLS56_RS30255_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /locus_tag="BLS56_RS30255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_1341"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_228772068.1"
                     /sec_met_domain="PP-binding (E-value: 7.1e-17, bitscore:
                     48.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1e-75, bitscore:
                     240.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-113, bitscore:
                     364.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREDQPGDQRLVSYVVGSVDGLRETVAARLPDYMVPSAFVVVGAL
                     PLTPNGKLDRASLPAPDVQTSGRAPRTPREEILCGLFAEVLGGPGVGIDDSFFDLGGHS
                     LLATRLVSRVRSVLGVETPIRALFETPTVAGLASTLDNAGQARAAVTAAQRPERVPLSF
                     AQQRLWFLQRFEGAGTTYNQPVALRLVGDLDADALEQALGDLVARHESLRTVFGEDAGG
                     PHQVVLDSARPVMERVATTERDLDAALKAAAAHPFALDTEIPLRAWLFETGPTEHALLL
                     LTHHIAGDGWSRTPMARDLATAYTARHAGRAPDWAPLPVQYADYALWQRSALGAEGDAD
                     SPLARQLAYWTEKLADLPEELDLPFDRPRPAMASYRGGRVRFTVPAEVHAGLAALARER
                     NATLFMVVQAALGLLLSRLGAGTDIPIGTPIAGRTDDALDGLIGVFLNTLVLRTDVSGD
                     PTLAEVVDRVRETDLAAYAHQDVPFERLVEVLNPTRSTARHPLFQVLLSIDNIDHHGAV
                     AGLAALPGLTASLLETDSGVAKFDLAFGLTETRDADGAATGLSGMVEYATDLLDESSAQ
                     AIADRFARVLAQAAAGAPIDVRTPAEHASLIADDAATDLPDASVADLITRQAAATPDAV
                     AVIAGRGSLTYSEVDTRANRLAGLLAARGAGPERLIGVALPRGVDLVVGLVAILKSGAG
                     YLPLDTDYPADRLAYMLDDAQPLLVLTTADLRDTLPPCETLETGDLDGDPIPVRPSLPS
                     SPAYVIYTSGSTGRPKGVVVPGAALTNFAVSMRDRLALGERDRLLAVTTVGFDIHGLEL
                     FVPLLSGAAVVVADRDEVRDPAAVAALVRAHDVSVIQATPSWWRAVVAEEAEALRGVRA
                     LVGGEALPADLARSLATVAVSVTNLYGPTETTIWSTASEVDDEPTIGGPIANTRVYVLD
                     AALRLVPPGVTGELYIAGAGVTRGYLNRPGLTAERFVADPFTGGRMYRTGDLVRRLPDG
                     ELVYLRRADDQVKLRGHRVELGEIRAALLDLPRVADAVVVVRADRLVAYVVGETGGLRA
                     ALAQRLPDYMVPSVFVALAALPLTPNGKIDRKALPEPEIRAEGRAPRTPREEILCGLFA
                     EVLGVVRVGIDDSFFDLGGHSLLATRLVSRVRSVLGVELAIRQLFVSPTVAGLSAALDG
                     AGAARGPVVAVSPRPERVPLSFAQRRLWFLHEFEGPSTAYTVPLALRLTGPLDIDALRQ
                     AFADVVARHEALRTVIRVDEDGPHQVVLDEAPRLEIARDGFTAALAYRFDLAAELPVRG
                     WLFNDGPDQWTLLLLTHHIATDAWSTGPLTRDLATAYTARAAGRAPDWTPLPVQYADYA
                     LWQHGSLGLESDPSSLAAQQVAFWSAALAGIPEELALPFDRPRPAVATFAGDRISFTVP
                     ADLHDRLTRVAKEARATLFMVVQAGVAALLARMGAGTDIPLGTPIAGRTDEALDDLVGF
                     FVNTLVLRTDLSGDPSFVDLIGRVRETALAAYANQDVPFERLVEVLNPARSLARHPLFQ
                     VMLAFTNDTGTAPTLPGIDAEGVAVGTDSAKFDLSFRFTETQDGLRGVLDFATDLFDRA
                     TAESLTRRLLTVLAALADDPSGPVHRTPVLDPAERHDLVVTRNATTRAVRRASLPELFA
                     EQAIATPDTVAVECGDNALTYAELDARANRLAHALGDVRGLVAIALPPTVDAVAAMLAV
                     LKAGAAYVPVDLASPPERVALILADAKPALVLTDGSIDLPASVSALRIDRVDWASLPDT
                     PPRQEIHPHDPAYVVYTSGSTGRPKGVVIEHRSLGAYLVRAREVYAPAVAGVSLAHTSL
                     AFDLTVTALFTPLVAGGRVRLGELGAATPTFTKATPSHLALLDTLPDTAAPTGLLILGG
                     EALHGEPLARWRERHPDAVVVNAYGPTEATVNCLDFRLEPGEPAPAGAVPVGRPFWNTR
                     AYVLDAGLQPVPSGVVGELYVAGDVLARGYLNRAALTAERFVADPFVEGERMYRTGDLV
                     RWNADGDLVYVGRADDQVKLRGFRVELEEIRSVLLEQPGIADAAVVVREDQPGDQRLVS
                     "
     source          1..6199
                     /db_xref="taxon:1271860"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0075257_134"
                     /organism="Actinokineospora iranica"
                     /strain="IBRC-M 10403"
                     /type_material="type strain of Alloactinosynnema iranicum"
     region          1..6199
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..6199
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..6199
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:6155](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..6155)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(90..152)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0026"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="2022"
                     /protein_start="2001"
                     /score="33.4"
                     /tool="antismash"
                     /translation="YVGRADDQVKLRGFRVELEEI"
     aSDomain        complement(117..1247)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_AMP-binding.2"
                     /evalue="7.10E-96"
                     /label="BLS56_RS30255_AMP-binding.2"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="2013"
                     /protein_start="1636"
                     /score="313.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FAEQAIATPDTVAVECGDNALTYAELDARANRLAHALGDVRGLVA
                     IALPPTVDAVAAMLAVLKAGAAYVPVDLASPPERVALILADAKPALVLTDGSIDLPASV
                     SALRIDRVDWASLPDTPPRQEIHPHDPAYVVYTSGSTGRPKGVVIEHRSLGAYLVRARE
                     VYAPAVAGVSLAHTSLAFDLTVTALFTPLVAGGRVRLGELGAATPTFTKATPSHLALLD
                     TLPDTAAPTGLLILGGEALHGEPLARWRERHPDAVVVNAYGPTEATVNCLDFRLEPGEP
                     APAGAVPVGRPFWNTRAYVLDAGLQPVPSGVVGELYVAGDVLARGYLNRAALTAERFVA
                     DPFVEGERMYRTGDLVRWNADGDLVYVGRADDQVKLR"
     aSModule        complement(117..2612)
                     /domains="nrpspksdomains_BLS56_RS30255_Condensation_LCL.2"
                     /domains="nrpspksdomains_BLS56_RS30255_AMP-binding.2"
                     /incomplete
                     /locus_tags="BLS56_RS30255"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(234..323)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0025"
                     /evalue="3.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1974"
                     /protein_start="1944"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PSGVVGELYVAGDVLARGYLNRAALTAERF"
     CDS_motif       complement(438..464)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0024"
                     /evalue="5.20E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1906"
                     /protein_start="1897"
                     /score="6.7"
                     /tool="antismash"
                     /translation="YGPTEATVN"
     CDS_motif       complement(795..854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0023"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1787"
                     /protein_start="1767"
                     /score="33.0"
                     /tool="antismash"
                     /translation="AYVVYTSGSTGRPKGVVIEH"
     CDS_motif       complement(1032..1073)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0022"
                     /evalue="8.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1708"
                     /protein_start="1694"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LAVLKAGAAYVPVD"
     CDS_motif       complement(1581..1700)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0021"
                     /evalue="6.20E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1525"
                     /protein_start="1485"
                     /score="76.5"
                     /tool="antismash"
                     /translation="RETALAAYANQDVPFERLVEVLNPARSLARHPLFQVMLAF"
     aSDomain        complement(1740..2612)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.50E-107"
                     /label="BLS56_RS30255_Condensation_LCL.2"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1472"
                     /protein_start="1181"
                     /score="349.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIATDA"
                     /tool="antismash"
                     /translation="ERVPLSFAQRRLWFLHEFEGPSTAYTVPLALRLTGPLDIDALRQA
                     FADVVARHEALRTVIRVDEDGPHQVVLDEAPRLEIARDGFTAALAYRFDLAAELPVRGW
                     LFNDGPDQWTLLLLTHHIATDAWSTGPLTRDLATAYTARAAGRAPDWTPLPVQYADYAL
                     WQHGSLGLESDPSSLAAQQVAFWSAALAGIPEELALPFDRPRPAVATFAGDRISFTVPA
                     DLHDRLTRVAKEARATLFMVVQAGVAALLARMGAGTDIPLGTPIAGRTDEALDDLVGFF
                     VNTLVLRTDL"
     CDS_motif       complement(1749..1838)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0020"
                     /evalue="8.30E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1469"
                     /protein_start="1439"
                     /score="47.1"
                     /tool="antismash"
                     /translation="DIPLGTPIAGRTDEALDDLVGFFVNTLVLR"
     CDS_motif       complement(2112..2144)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0019"
                     /evalue="3.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1348"
                     /protein_start="1337"
                     /score="16.2"
                     /tool="antismash"
                     /translation="QYADYALWQHG"
     CDS_motif       complement(2193..2255)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0018"
                     /evalue="2.20E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1321"
                     /protein_start="1300"
                     /score="29.8"
                     /tool="antismash"
                     /translation="HHIATDAWSTGPLTRDLATAY"
     CDS_motif       complement(2433..2546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0017"
                     /evalue="5.00E-20"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1241"
                     /protein_start="1203"
                     /score="63.9"
                     /tool="antismash"
                     /translation="TAYTVPLALRLTGPLDIDALRQAFADVVARHEALRTVI"
     CDS_motif       complement(2565..2597)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0016"
                     /evalue="6.00E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1197"
                     /protein_start="1186"
                     /score="9.3"
                     /tool="antismash"
                     /translation="SFAQRRLWFLH"
     aSDomain        complement(2658..2861)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_PCP.2"
                     /evalue="2.50E-28"
                     /label="BLS56_RS30255_PCP.2"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1166"
                     /protein_start="1098"
                     /score="90.1"
                     /tool="antismash"
                     /translation="EEILCGLFAEVLGVVRVGIDDSFFDLGGHSLLATRLVSRVRSVLG
                     VELAIRQLFVSPTVAGLSAALDG"
     aSModule        complement(2658..5687)
                     /complete
                     /domains="nrpspksdomains_BLS56_RS30255_Condensation_LCL.1"
                     /domains="nrpspksdomains_BLS56_RS30255_AMP-binding.1"
                     /domains="nrpspksdomains_BLS56_RS30255_PCP.2"
                     /locus_tags="BLS56_RS30255"
                     /monomer_pairings="Gly -> Gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2823..2855)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0015"
                     /evalue="2.20E-01"
                     /label="Cy4"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1111"
                     /protein_start="1100"
                     /score="4.8"
                     /tool="antismash"
                     /translation="ILCGLFAEVLG"
     CDS_motif       complement(2907..2933)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0014"
                     /evalue="1.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1083"
                     /protein_start="1074"
                     /score="5.5"
                     /tool="antismash"
                     /translation="GKIDRKALP"
     CDS_motif       complement(3117..3179)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0013"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1013"
                     /protein_start="992"
                     /score="31.7"
                     /tool="antismash"
                     /translation="YLRRADDQVKLRGHRVELGEI"
     aSDomain        complement(3144..4283)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_AMP-binding.1"
                     /evalue="1.80E-107"
                     /label="BLS56_RS30255_AMP-binding.1"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="1004"
                     /protein_start="624"
                     /score="351.4"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="TRQAAATPDAVAVIAGRGSLTYSEVDTRANRLAGLLAARGAGPER
                     LIGVALPRGVDLVVGLVAILKSGAGYLPLDTDYPADRLAYMLDDAQPLLVLTTADLRDT
                     LPPCETLETGDLDGDPIPVRPSLPSSPAYVIYTSGSTGRPKGVVVPGAALTNFAVSMRD
                     RLALGERDRLLAVTTVGFDIHGLELFVPLLSGAAVVVADRDEVRDPAAVAALVRAHDVS
                     VIQATPSWWRAVVAEEAEALRGVRALVGGEALPADLARSLATVAVSVTNLYGPTETTIW
                     STASEVDDEPTIGGPIANTRVYVLDAALRLVPPGVTGELYIAGAGVTRGYLNRPGLTAE
                     RFVADPFTGGRMYRTGDLVRRLPDGELVYLRRADDQVKLR"
     CDS_motif       complement(3258..3347)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0012"
                     /evalue="5.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="966"
                     /protein_start="936"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PPGVTGELYIAGAGVTRGYLNRPGLTAERF"
     CDS_motif       complement(3444..3467)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0011"
                     /evalue="6.40E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="904"
                     /protein_start="896"
                     /score="6.5"
                     /tool="antismash"
                     /translation="YGPTETTI"
     CDS_motif       complement(3834..3890)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0010"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="774"
                     /protein_start="755"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVP"
     CDS_motif       complement(4059..4097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0009"
                     /evalue="7.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="699"
                     /protein_start="686"
                     /score="13.0"
                     /tool="antismash"
                     /translation="AILKSGAGYLPLD"
     CDS_motif       complement(4638..4751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0008"
                     /evalue="5.50E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="506"
                     /protein_start="468"
                     /score="70.2"
                     /tool="antismash"
                     /translation="RETDLAAYAHQDVPFERLVEVLNPTRSTARHPLFQVLL"
     aSDomain        complement(4788..5687)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.20E-118"
                     /label="BLS56_RS30255_Condensation_LCL.1"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="456"
                     /protein_start="156"
                     /score="386.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="ERVPLSFAQQRLWFLQRFEGAGTTYNQPVALRLVGDLDADALEQA
                     LGDLVARHESLRTVFGEDAGGPHQVVLDSARPVMERVATTERDLDAALKAAAAHPFALD
                     TEIPLRAWLFETGPTEHALLLLTHHIAGDGWSRTPMARDLATAYTARHAGRAPDWAPLP
                     VQYADYALWQRSALGAEGDADSPLARQLAYWTEKLADLPEELDLPFDRPRPAMASYRGG
                     RVRFTVPAEVHAGLAALARERNATLFMVVQAALGLLLSRLGAGTDIPIGTPIAGRTDDA
                     LDGLIGVFLNTLVLRTDVS"
     CDS_motif       complement(4800..4889)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0007"
                     /evalue="1.40E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="452"
                     /protein_start="422"
                     /score="40.0"
                     /tool="antismash"
                     /translation="DIPIGTPIAGRTDDALDGLIGVFLNTLVLR"
     CDS_motif       complement(5157..5195)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0006"
                     /evalue="1.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="333"
                     /protein_start="320"
                     /score="17.6"
                     /tool="antismash"
                     /translation="QYADYALWQRSAL"
     CDS_motif       complement(5244..5306)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0005"
                     /evalue="1.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="304"
                     /protein_start="283"
                     /score="27.5"
                     /tool="antismash"
                     /translation="HHIAGDGWSRTPMARDLATAY"
     CDS_motif       complement(5508..5621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0004"
                     /evalue="4.10E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="216"
                     /protein_start="178"
                     /score="61.0"
                     /tool="antismash"
                     /translation="TTYNQPVALRLVGDLDADALEQALGDLVARHESLRTVF"
     CDS_motif       complement(5640..5672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0003"
                     /evalue="6.10E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="172"
                     /protein_start="161"
                     /score="9.3"
                     /tool="antismash"
                     /translation="SFAQQRLWFLQ"
     aSDomain        complement(5727..5933)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS30255_PCP.1"
                     /evalue="5.90E-28"
                     /label="BLS56_RS30255_PCP.1"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="143"
                     /protein_start="74"
                     /score="88.9"
                     /tool="antismash"
                     /translation="EEILCGLFAEVLGGPGVGIDDSFFDLGGHSLLATRLVSRVRSVLG
                     VETPIRALFETPTVAGLASTLDNA"
     CDS_motif       complement(5895..5927)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0002"
                     /evalue="2.00E-01"
                     /label="Cy4"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="87"
                     /protein_start="76"
                     /score="5.0"
                     /tool="antismash"
                     /translation="ILCGLFAEVLG"
     CDS_motif       complement(5979..6005)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS30255_0001"
                     /evalue="2.40E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="BLS56_RS30255"
                     /protein_end="59"
                     /protein_start="50"
                     /score="2.0"
                     /tool="antismash"
                     /translation="GKLDRASLP"
ORIGIN
        1 taggacacca gccgctggtc ccccggctgg tcctcacgca ccacaacagc ggcgtcagcg
       61 atccccggct gctccaacag aaccgagcga atctcctcca actcgacccg aaacccgcgc
      121 agcttcacct gatcatcagc ccggcccaca taaaccaagt caccatcggc gttccaccgc
      181 accagatccc cggtccggta catccgctca ccctcgacga acgggtccgc cacaaaccgc
      241 tcagccgtca acgccgcccg gttcaaatac ccacgagcga gaacgtcacc cgccacgtac
      301 aactccccaa ccacaccgga cggaaccggc tgcaaaccgg catccaacac atacgcccgg
      361 gtattccaaa acggccgacc caccggaacc gcacccgcag gcgccggctc ccccggctcc
      421 aagcgaaagt ccagacagtt caccgtcgcc tcagtcgggc cgtaggcgtt gacgaccacg
      481 gcgtccgggt gccgctcgcg ccagcgggcc agcggctcgc cgtgcagggc ttcgccgccg
      541 aggatcagca gcccggtggg cgcggcggtg tccggcaggg tgtccagcag ggccaggtgc
      601 gagggggtcg ccttggtgaa ggtcggcgtg gccgccccga gttcgcccag gcgcacccgg
      661 ccaccggcga ccagcggggt gaacagggcg gtcacggtga ggtcgaaggc gagcgaggtg
      721 tgcgccagcg acaccccggc cacggcgggc gcgtagacct cgcgggcgcg caccaggtag
      781 gcgcccagtg agcggtgctc gatcacgacg cccttgggcc tgcccgtcga cccggaggtg
      841 tagacgacat acgccgggtc gtgcgggtgg atctcctggc gcggcggggt gtcgggcagg
      901 ctcgcccagt ccacccggtc gatccgcaac gcggaaacgc ttgcgggcag gtcgatcgag
      961 ccgtcggtga gcaccagggc gggcttggcg tcggcgagga tgagcgccac ccgctccggc
     1021 ggcgaggcga ggtcgacggg cacgtaggcc gcgcccgctt tgaggacggc gagcatcgcg
     1081 gccacggcgt cgacggtcgg cggcaacgcg atcgccacca gaccgcgcac gtcgccgagg
     1141 gcgtgcgcga ggcggttggc gcgtgcgtcc agttccgcgt aggtcagcgc gttgtcgccg
     1201 cactccaccg cgaccgtgtc cggggtcgcg atggcctgct cggcgaacag ctccggcagg
     1261 ctcgcccgcc gcaccgcgcg ggtcgtggcg ttgcgggtga ccaccaagtc gtgccgctcg
     1321 gccgggtcca gcaccggcgt gcggtggact ggcccgctgg ggtcgtcggc caaggcggcg
     1381 agcacggtga gcagcctgcg ggtcaggctt tccgcggtgg cgcggtcgaa caggtcggtg
     1441 gcgaagtcga gcacgccgcg caggccgtcc tgggtctcgg tgaaccggaa ggacaggtcg
     1501 aacttggcgg agtcggtgcc caccgcgacg ccctcggcgt cgatgccggg cagggtcggc
     1561 gcggttcccg tgtcgttggt gaacgccagc atgacttgga acagcgggtg ccgggccagc
     1621 gaccgggccg ggttcagcac ctccaccaac cgctcgaacg gcacatcctg gttcgcgtac
     1681 gccgccaacg cggtctcccg cacccggccg atgaggtcta caaaggacgg gtcgccggac
     1741 aggtcggtgc gcagcaccaa cgtgttcacg aagaacccga caaggtcgtc cagggcctcg
     1801 tccgtccggc ccgcgatcgg cgtgcccagt ggaatgtccg tgcccgcgcc catccgggcc
     1861 aacaacgccg ccacaccggc ctgcaccacc atgaacagcg ttgcccgcgc ttccttggcc
     1921 acccgggtca ggcgatcgtg gaggtctgcg gggacggtga aggagatccg gtcgcccgcg
     1981 aaggtggcca ccgcgggacg ggggcggtcg aacggcaggg ccagttcctc aggaatgccc
     2041 gccagcgcgg ccgaccagaa cgcgacctgc tgggcggcca ggctcgacgg gtcggactcc
     2101 aggccgagcg aaccgtgctg ccagagggcg taatcggcgt actgcaccgg caacggcgtc
     2161 cagtcgggcg ctcgaccggc cgcgcgggcg gtgtaggcgg tggcgaggtc gcgggtcagc
     2221 gggccggtgg accaggcgtc ggtggcgatg tggtgggtca ggagcaacag cgtccattgg
     2281 tccgggccgt cattgaacag ccaaccccga accggtagct ccgcggccaa gtcgaaccgg
     2341 taggccaggg ccgcggtgaa gccgtcccga gcgatctcaa ggcgcggcgc ctcatcgagg
     2401 acgacctggt gcgggccgtc ttcgtccacg cgaatcaccg tgcgcagcgc ctcgtgccgc
     2461 gccacgacgt ccgcgaaggc ctgccgcagg gcgtcgatgt cgagcggccc ggtcaggcgc
     2521 agcgcgagcg gaacggtgta ggcggtgctc gggccctcga actcgtgcag gaaccacagc
     2581 cgccgctgcg cgaacgacag cggcacccgc tccggccgcg gcgacaccgc caccaccggg
     2641 ccgcgcgccg cgcccgcgcc gtccagcgcg gccgacagcc cggcgaccgt gggcgagacg
     2701 aaaagctgcc ggatggccag ctccacgccg agcaccgacc gcacccggct caccagccgg
     2761 gtcgccagca gcgaatgccc gcccaggtcg aagaaggagt cgtcaatgcc cacccggacc
     2821 acgcccagca cctcggcgaa cagtccacaa aggatttcct cgcggggcgt gcgcggcgcg
     2881 cgaccctcgg cccggatttc gggctcgggc agggctttac ggtcgatctt gccgttcggg
     2941 gtcagtggga gggcggccaa cgccacgaac accgacggca ccatgtagtc gggcagccgc
     3001 tgggccagcg cagcgcgcag cccgccggtc tcgccgacga cataggcgac cagccggtcc
     3061 gcccgcacga ccacgaccgc gtccgcgaca cgcggcagat ccagcagggc ggcgcggatc
     3121 tcgccgagtt cgacgcggtg gccgcgcagc ttcacctggt cgtcggcgcg gcgcaggtag
     3181 acgagttctc cgtcgggcag gcggcgcacc aggtccccgg tgcggtacat gcgcccgccg
     3241 gtgaacgggt cggcgacgaa ccgctcggcg gtcagccccg ggcggttgag gtagccgcgc
     3301 gtgacgcccg cgcctgcgat atacaactcg cctgtgacac ccggcggaac cagccgcagg
     3361 gcggcgtcga ggacgtagac ccgggtgttc gcgatcgggc cgccgatggt cggctcatcg
     3421 tccacttcgg acgccgtgga ccagatcgtg gtctcggtgg ggccgtagag gttggtcacc
     3481 gacaccgcga ccgtggccag cgaccgggcc aggtccgcgg gcagggcctc gccgccgacg
     3541 agcgcgcgga caccccgcag cgcctcggct tcctcggcca ccaccgcccg ccaccagctc
     3601 ggggtcgcct ggatgaccga cacgtcgtgc gcgcgcacca gggcggcgac ggcggccggg
     3661 tcgcgcacct cgtcgcgatc ggcgacgaca accgccgcgc cggacagcag cggcacgaac
     3721 agctccaggc cgtggatgtc gaacccgacc gtggtcaccg ccagcagccg gtcccgctcg
     3781 cccagcgcga gccggtcgcg catcgacacc gcgaagttcg tcagcgcggc ccccggcacc
     3841 acgacgccct tgggcctgcc ggtcgagccg gacgtgtaga tcacgtatgc cggagaactg
     3901 gggagactcg gccggaccgg aatcgggtcg ccgtcgaggt cgccggtctc cagcgtctcg
     3961 cacggcggca aggtgtcgcg caggtcggcg gtggtcagca ccagcagcgg ctgggcgtcg
     4021 tcgagcatgt acgccaaccg gtcggccggg tagtcggtgt cgagcggcag atagcccgca
     4081 ccggatttca ggatcgcgac cagccccacc accaggtcga cgccgcgcgg cagggcgacc
     4141 ccgatcagcc gctccgggcc cgcgccgcgc gccgccagca atccggccag ccggttcgcc
     4201 cgggtgtcca cttcggaata ggtgagcgaa ccccggcccg cgatcacggc caccgcgtcc
     4261 ggtgtcgccg ccgcttggcg ggtgatcagg tcggccacgg acgcgtccgg caggtccgtc
     4321 gcggcgtcgt ccgcgatgag cgacgcgtgc tcggcggggg tgcggacgtc gatgggcgcg
     4381 cccgcggcgg cctgggcgag gaccctggcg aaccggtcgg cgatggcctg ggccgaggac
     4441 tcgtccagca ggtcggtggc gtactcgacc atccccgaca gcccggtagc cgcgccgtcg
     4501 gcgtcccggg tctcggtgag gccgaaggcg aggtcgaact tggccacgcc cgaatcggtc
     4561 tccagcagcg acgcggtgag gccgggcagc gccgccaagc ccgcgacagc gccgtggtgg
     4621 tcgatattgt cgatggagag cagtacttgg aaaagcgggt gccgcgcggt ggaccgggtg
     4681 gggttgagca cttcgaccag ccgctcgaac ggcacgtcct ggtgcgcgta cgcggccaag
     4741 tcggtctccc gcacccggtc gaccacctcg gcgagggtcg ggtcgccgga cacgtccgtg
     4801 cgcagcacca gtgtgttgag gaagacgccg atgagcccgt cgagggcgtc gtcggtgcgg
     4861 cccgcgatcg gcgtgccgat cgggatgtcc gtgccagccc caagccggga cagcagcagg
     4921 cccaacgcgg cctggacgac catgaacagc gtcgcgttcc gctcccgcgc cagcgccgcg
     4981 aggcccgcgt gcacctcggc gggcacggtg aaccgcactc gaccgccgcg atacgaggcc
     5041 atcgcgggtc gggggcggtc gaagggcagg tccagttctt ccggcaggtc ggccagtttc
     5101 tcggtccaat aagcgagttg ccgcgcgagc gggctgtccg cgtcgccttc cgcgcccaag
     5161 gccgagcgct gccacagggc gtagtccgcg tactgcaccg gaagcggcgc ccagtccggg
     5221 gcgcgaccgg cgtgccgggc ggtgtaggcg gtggccaggt cgcgcgccat cggggtccgg
     5281 gaccagccgt cgcccgcgat gtggtgggtc agcaggagca gggcgtgctc ggtggggccg
     5341 gtctcgaaca gccaagcccg cagcggaatc tcggtgtcga gcgcgaacgg gtgcgcggcc
     5401 gccgccttga gcgcggcgtc gagatcgcgc tcggtggtgg ccacgcgttc catgaccggg
     5461 cgggcggaat cgaggacgac ctggtgcggc ccgccggcgt cctcgccgaa gaccgtgcgg
     5521 aggctttcgt gccgggccac caggtcgccc agggcctgct ccagcgcgtc ggcgtcgagg
     5581 tcgccgacga gccgcagcgc gaccggctgg ttgtaggtgg tgcccgcgcc ctcgaagcgc
     5641 tgtaggaacc acaggcgctg ctgcgcgaac gacagcggga cccgctccgg tcgctgggcg
     5701 gcggtgacag cggcccgtgc ttggcccgcg ttgtcgaggg tgctcgcgag cccggcgacg
     5761 gtcggcgtct cgaacagcgc acggatcggc gtctccacgc ccagcaccga ccgcacccgg
     5821 ctcaccagcc gggtcgccaa cagcgaatgc ccgcccaggt cgaagaacga gtcatcgatc
     5881 ccgaccccgg gaccgcccag cacctcggcg aacagtccac agaggatttc ctcgcgcggc
     5941 gtgcgcggcg cgcggcccga cgtctggacg tccggcgcgg gcaaggacgc gcggtccagc
     6001 tttccgttcg gtgtcagcgg aagcgcgccc accacgacga acgcggacgg caccatgtag
     6061 tccggcagcc gcgccgccac cgtttcccgc agcccgtcca ccgaaccaac cacataggac
     6121 accagccgct ggtcccccgg ctggtcctca cgcaccacaa cagcggcgtc agcgatcccc
     6181 ggctgctcca acagaaccg
//
