LOCUS       NZ_FMZZ01000019        22616 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinokineospora iranica strain IBRC-M 10403, whole genome shotgun
            sequence.
ACCESSION   NZ_FMZZ01000019
VERSION     NZ_FMZZ01000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora iranica
  ORGANISM  Actinokineospora iranica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:26:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,202
            CDSs (total)                      :: 6,139
            Genes (coding)                    :: 6,038
            CDSs (with protein)               :: 6,038
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 25 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 7 of 103
            Pseudo Genes (multiple problems)  :: 18 of 103
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70008
            Orig. end                         :: 92624
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMZZ01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22616
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22616
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22616
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12616](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12616
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    205..221
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     gene            803..1687
                     /gene="panC"
                     /locus_tag="BLS56_RS27400"
                     /old_locus_tag="SAMN05216174_11964"
     CDS             803..1687
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015787821.1"
                     /locus_tag="BLS56_RS27400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11964"
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_091456674.1"
                     /transl_table=11
                     /translation="MTRFTAGKLHVHTSPEQLAKVTRALRATGRKIAFVPTMGALHAGH
                     RELMSRARRIPNTVLVASIFVNPLQFGAGEDFDRYPRPLDADLAACEEERVELVFTPAR
                     EALYPPDAQVTVHAGPLGEELEGAARPGHFSGVLTVVAKLFNIVRPDYALFGEKDYQQL
                     VLIKKMVRDLDMEPHIIGVPTVRETDGLALSSRNAFLDADQRAAAVALSAALTAGQYAG
                     REGEQAVLASARDVLARTPELKVDYVALRDPDLGPAPERGDARLLVAAKLGDTRLIDNV
                     PVLLGRPDLAQHG"
     gene            1702..2175
                     /gene="panD"
                     /locus_tag="BLS56_RS27405"
                     /old_locus_tag="SAMN05216174_11965"
     CDS             1702..2175
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641940.1"
                     /locus_tag="BLS56_RS27405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11965"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_091456676.1"
                     /transl_table=11
                     /translation="MFRTMLKSKIHRATVTQADLHYVGSVTVDPILLEAADLLPGEQVA
                     IVDITNGARLETYVIEGERGSGVIGINGAAAHLVHPGDLVILISYGLMDSAEAAAYVPK
                     IVFVDADNRIVHLGGDAGHAPADSGLRSGAVTADPPAETADAAKLDALLAHES"
     gene            2183..2959
                     /locus_tag="BLS56_RS27410"
                     /old_locus_tag="SAMN05216174_11966"
     CDS             2183..2959
                     /EC_number="2.7.1.33"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097811.1"
                     /locus_tag="BLS56_RS27410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11966"
                     /product="type III pantothenate kinase"
                     /protein_id="WP_091456678.1"
                     /transl_table=11
                     /translation="MLLTIDVGNTNIALGLHTDGDLLRDWRMRTDARITADELALTMRG
                     LLGEHADRVTGISALSTVPAVLRELRVMLGRYHPRVPRVIVEPGVRTGVPLLVDNPKEV
                     GADRVINTLAAHHLFSTACVVVDFGTSTNIDVISAKGEFLGGVFMPGIEISVDALAARA
                     AALRKVEMVRPRSVIGKNTVECLQSGIMFGFAGQVDGLVTRISRELERTGHQGPVTVIA
                     TGGLAPLVVDESDTIQHHRPDLTLMGLRLVFERNSR"
     gene            complement(2963..3703)
                     /locus_tag="BLS56_RS27415"
                     /old_locus_tag="SAMN05216174_11967"
     CDS             complement(2963..3703)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097812.1"
                     /locus_tag="BLS56_RS27415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11967"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_091456681.1"
                     /transl_table=11
                     /translation="MDESELFAKRASSFGANAAAYAQHRPGYPAEAIEWVIGDRMRVLD
                     LAAGTGRLTEGLLAFGLEVTAVEPDEAMRAELTRRIPDVPALDGSAEDIPLPDASVEAV
                     LVGHAFHWFNTDKALTEITRVLRPGGVFGALWNHDDLTVDWVAGLAELTATSLGEVQRV
                     KVDVPSHDLLEPHELKTFPHRQRRTVESLLATLGTHSQISVADATERAQVFDRVRTYLW
                     SRPETSAGEFDRPLITSVVRAIRR"
     gene            3828..5282
                     /gene="lysS"
                     /locus_tag="BLS56_RS27420"
                     /old_locus_tag="SAMN05216174_11968"
     CDS             3828..5282
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lysS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165382.1"
                     /locus_tag="BLS56_RS27420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11968"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_175483076.1"
                     /transl_table=11
                     /translation="MRIRREKRERLLAAGVEPYPVELPRTHTLAQVREAYSDLPTDTAT
                     GDKVAVTGRVMFVRNTGKLCFATLREGDGTELQAMLSLDKVGADALSAWKSDVDLGDHV
                     FVSGEVITSRRGELSVLADEWRLAAKALRPLPVAHKALSEEVRIRQRYVDLILRPRARE
                     TVRNRAGVVRSLRESFHSRGFIEVETPMLQTVHGGAAARPFSTQSNAMDMELFLRIAPE
                     LYLKRCLVGGLEKVFEINRNFRNEGSDSTHSPEFAMLEYYEAYATYDTNAAMTRALVQE
                     AAESVFGSQVVTLDDGSEYDLSGEWTTLTMYGSLSGALGTEITPDTPADLLRKHSVALG
                     LELDPAYGHGKLVEELWEHLVGDHLHAPTFVRDFPLETSPLTRQHRTERGVAEKWDLYV
                     RGFELATGYSELVDPVVERERLEDQARLGAAGDDEAMRVDEDFLRAMEYGMPPSGGVGM
                     GIDRLLMALTGLGIRETILFPLVRPE"
     gene            5432..5779
                     /locus_tag="BLS56_RS27425"
                     /old_locus_tag="SAMN05216174_11969"
     CDS             5432..5779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683825.1"
                     /locus_tag="BLS56_RS27425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11969"
                     /product="Lsr2 family protein"
                     /protein_id="WP_091456686.1"
                     /transl_table=11
                     /translation="MAQKVTVSLVDDLDGSEAEETVQFGLDGASYEIDLSGDNADRLRE
                     ALADFIDHARRSGGRKRPVGKAASGRVPRTASADREQNQAIREWARKQGMKVSDRGRIP
                     SDVLDAYNQQA"
     gene            complement(5881..6714)
                     /locus_tag="BLS56_RS27430"
                     /old_locus_tag="SAMN05216174_11970"
     CDS             complement(5881..6714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782966.1"
                     /locus_tag="BLS56_RS27430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11970"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_091456689.1"
                     /transl_table=11
                     /translation="MTAGYRIEAGLRDRQGYLADSLDRVNPRQARATVRFGLPEDRSRW
                     TRCADFLAMPDGFARWREGLASWLTETYGDSPERTTAGYVMNWYLTVPGYVAGLLFHHE
                     RRVPSLRPADLAFRMAQPRPHPDAIAVLSPRFVCLPDDPAAGTPEATVVSDERALAAVL
                     RGRFTAHAARFVEVFAPQVRLGRRMLWAAATDVLDNSLWLAGRYGGDEGAGVLDAALVL
                     ADGPAPLTSDSTLRPLAESGGPTRWTRRRESCCFHYLLEAGQGTCQTCPRVCRKN"
     misc_feature    6789..6807
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     misc_feature    complement(6874..6889)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.49"
                     /tool="antismash"
     gene            7092..9653
                     /locus_tag="BLS56_RS27435"
                     /old_locus_tag="SAMN05216174_11971"
     CDS             7092..9653
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782967.1"
                     /locus_tag="BLS56_RS27435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11971"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_091456691.1"
                     /transl_table=11
                     /translation="MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVA
                     AKALESLGIALEGVRQQVEEIIGQGQHAPSGHIPFTPRAKKVLELSLREALQLGHNYIG
                     TEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGGKESTETGGRGEGTPS
                     SSLVLDQFGRNLTASAREGKLDPVIGRTKEIERVMQVLSRRTKNNPVLIGEPGVGKTAV
                     VEGLAQMVVKGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIKTRGDIIL
                     FIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKYVEKDPALERRFQ
                     PIQVGEPSLEHTIEILKGLRDRYEAHHRVTITDAALVSAATLADRYINDRFLPDKAIDL
                     IDEAGARMRIRRMTAPPDLREFDEKIADVRREKESAIDAQDFERAAKLRDTEKQLLGQK
                     AEREKQWKDGDLDVVAEVDDEQIAEVLANWTGIPVFKLTEEETSRLLRMEDELHKRIIG
                     QEDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGEDDALIQ
                     IDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEVYNTL
                     LQVLEDGRLTDGQGRTVDFKNTVIIFTSNLGTQDISKAVGLGFTSGNDQGSNYERMKNK
                     VNDELKKHFRPEFLNRIDDIIVFHQLTEQQIITMVDLMINRVETQLKNKDMAIELTDKA
                     KKLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGEIEAGQIIITDVEGWDGEEGSA
                     DKAKFVFRGEPKPTRVPDSLPVELSAPSGGAESGEGSEPTE"
     misc_feature    complement(9698..9707)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    9921..9938
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.77"
                     /tool="antismash"
     misc_feature    9953..9966
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.64"
                     /tool="antismash"
     gene            10001..12616
                     /gene="lanKC"
                     /locus_tag="BLS56_RS27440"
                     /old_locus_tag="SAMN05216174_11972"
     CDS             10001..12616
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800164.1"
                     /locus_tag="BLS56_RS27440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11972"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_091456694.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1107.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.4e-10, bitscore: 32.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-11, bitscore:
                     36.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLQYEAFCFVDPLFFDQPRQTATTLNGFSTRLPAPHEGWVDGVA
                     GIWRMLRPVGVTLPGQGWKIHVSATLGNAERVLSAVHAHCLDRGLAYKHLLSPSVLLAR
                     NSKYAPRSGSGKLVTIYPVDDDSFSQVLAELSTLLDGEAGPYILSDLRIGSGPLYVRYG
                     GFAEQWVEIDGTRVLAVRTPDGTLVPDKREPTFSVPDWVTVPDCLAPHIAARKAGNPDD
                     FPYRVTASMHFSNGGGVYRATRKSDGAEVVLKEARPHAGLDRDGVDAVARLRGEHDILV
                     RLADVDGVPAAHDLVTVWEHTFLAMEPVAGQSLGSWLARTYPLTRQHASDEAVAEYTER
                     ALTVLGRVEDLLARVHERGVMFGDLHALNIIIDDDDRVSLIDFEMASAAAEPGRPALGA
                     PGFRAPAGRTGFDVDRYALAALRLWIFLPLNALLELAPGRLDALVDVIERRFPLPPGYG
                     DGIRRELRQTDQAETDQAATAPAATELDRPDPDWGQVRKALAVAILASATPERDDRLFP
                     GDIEQFRVGGACFGYGAAGVLHALDAAGTGRYPEHERWLIDTVRRTPPARPGFFDGAHG
                     IAHVLENLGHHEDAAAVLDGADNLVAQTRDHSLDGGLSGIALNLLHFAGTRHDRDLRTR
                     AHGIGDRLADALRAATPSPFARAGLLNGWSGVALLFLRLHDDTGDRGWLDLAEQAISRD
                     LDECVTTDDGVLQVRDQGARTLPYLSIGSAGIALVAEELAARRPDSAILERQPDLLRAC
                     HGEFVIHPGLLFGRCGLLVTLAAAQRRAADPERAEVIGRHLAALGWHAVPHGDGGIAMP
                     GNQLLRLSMDLATGGAGVLLAVTATLDGHGRVLPFLGDAPHPPISGHPAGEKERNTSWR
                     "
     misc_feature    10076..10078
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11267..11269
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12607..12750
                     /locus_tag="BLS56_RS27445"
                     /old_locus_tag="SAMN05216174_11973"
     CDS             12607..12750
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949109.1"
                     /locus_tag="BLS56_RS27445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11973"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_091456696.1"
                     /transl_table=11
                     /translation="MEMILNLQELEAPNELSHNDGGGHGGASNLSLLASCANSTVSLLT
                     CH"
     CDS_motif       12607..12672
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEMILNLQELEAPNELSHNDGG"
                     /locus_tag="BLS56_RS27445_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12673..12750
                     /prepeptide="core"
                     /locus_tag="BLS56_RS27445_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="11.10"
                     /molecular_weight="2287.5"
                     /monoisotopic_mass="2286.2"
                     /core_sequence="GHGGASNLSLLASCANSTVSLLTCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEMILNLQELEAPNELSHNDGG"
                     /leader_location="[12606:12672](+)"
                     /alternative_weights="2305.6"
                     /alternative_weights="2323.6"
                     /alternative_weights="2341.6"
                     /alternative_weights="2359.6"
                     /alternative_weights="2377.6"
     gene            12874..14496
                     /locus_tag="BLS56_RS27450"
                     /old_locus_tag="SAMN05216174_11974"
     CDS             12874..14496
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007027061.1"
                     /locus_tag="BLS56_RS27450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11974"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_175483077.1"
                     /transl_table=11
                     /translation="MVRRDRGWVALLVATALIATAAGLLLPAALAAALDSVRAGGSAVL
                     WVVVLGAVGILAEVAGVVLTARVTANATARLRADLGDHLVRLGTHSDFADGDAVSRITG
                     DCIGAGQIAALAVQLLGALLMSAGAITALALLDWRLAAVFLCAVPLALLLARSHLRLTA
                     ADVQAYQEVSGELGARLLDAVAGLRTITAAGVADQETARVLRPLPRLSAAGAGMWRTQA
                     RMVWRAGLLMPAVQVTVLAAAGFGVLTGRLTIGDMLAALGYAVLGLGVVRQIPLLTTLS
                     RARSCASRIAAVLDTPAEDSAGQALPPGPGVVEVRRVGVDGALSEVDFVIPAGTAVAVV
                     GRSGSGKSVLASVLAGLRRPDRGEVRLDGVPLSAVADADLRATIGCAFERPALLGSSVR
                     AAVAYGVTADEAAVRAACRLAQVDDLVVRLPDGYATPLSRTPLSGGEAQRLGLARAVVR
                     TPRLLVLDDATASLDTVTEAQVEAALAARPHTRVTITHRAGVASRADLVVWLDGGRVRG
                     FGPHDVLWGESAYRAVFTEEEAR"
     gene            14837..16615
                     /locus_tag="BLS56_RS27455"
                     /old_locus_tag="SAMN05216174_11975"
     CDS             14837..16615
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010312163.1"
                     /locus_tag="BLS56_RS27455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11975"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_091456759.1"
                     /transl_table=11
                     /translation="MTVTRAYWRGLGGHWRAWSALLACSLLEALPAFLSGRLVQRAVDD
                     GFAVGRLGVGLAWLAGFAVAAVVGAFGARLVWQRLGVVIEPLRDSLVRLVVGGVLHDPA
                     PPRGGPDAAGVARITQHVEVIRDATAGLLVQARGLVVTVVGALAGVTAMAGELAWLVAV
                     PVVAALAVFVALLPTLARRQRALALADEHTAGTVGGVLTGMRDVVACGARDVAAGEVRA
                     AVRAQAGAAVRMATAAASRTLVIAVGAFLPLVLVLLSAPAAVSHGSLTAGAVLGTLVYL
                     TGTLTPALHSLAATASTVVLRLLVALRRLDEVHPPPPTVGTEKPAHGVITVRALTHRWG
                     EHAEPVLRDLDLDLAPGDHLAVVGPSGIGKSTLAGILTGTLLPTSGEVRLGGVPVTDID
                     PAHRHRLIAFTPQESYIFAGTVRENLSLLAPTADDRHLQAAADAVGAANLIHRLGGLSA
                     LLDHAGAGLSAGERQLLALTRVYASPATIVVLDEATANLDPPTEAQAEHAFATRDGILI
                     VIAHRLTSAIRAPQVLLMDGRETHLGDHPTLLATSPAYAALMHAWAPLANTQRHPHDRE
                     LSTGADRPLPRADLRR"
     misc_feature    14915..14917
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16565..16567
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16778..17617)
                     /locus_tag="BLS56_RS27460"
                     /old_locus_tag="SAMN05216174_11976"
     CDS             complement(16778..17617)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441631.1"
                     /locus_tag="BLS56_RS27460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11976"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_091456700.1"
                     /transl_table=11
                     /translation="MDNLFDVELTMKLLSLDFVLGALLVAAILGLLAGVLGPLIVARNM
                     AFSVHGTSELALTGGAAALLLGWEVGNGALAGAIVAALVLGLLSRRSSDYDSVIGVVLA
                     FGLGMGVLMLWLYKGRASNKFGLLTGQIVGQDFASIALLTGCAVGVFVVLALLYRPLLF
                     ASVDADVARARGVPTTGLALVFAVLVGVATALGVRTVGSLLVLALMVTPAAAACRVTAS
                     PLRATLLAILFAEVSAVGGIVLSLAPGAPVSAFVTAISFLIYLVCWVISRVRRAAFA"
     misc_feature    complement(17584..17604)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            complement(17618..18478)
                     /locus_tag="BLS56_RS27465"
                     /old_locus_tag="SAMN05216174_11977"
     CDS             complement(17618..18478)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010308355.1"
                     /locus_tag="BLS56_RS27465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11977"
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="WP_091456703.1"
                     /transl_table=11
                     /translation="MTVERSTAPPAAPPVPGGAAAVSLTDARLAYGDRVLWDGLDLDVR
                     PGEFLAVLGPNGSGKTSLMRVLLGLQKLSGGTVNVAGEPPGKGNRRIGYIPQQRALDPT
                     LALRGRDLVGLGYDGHRWGLGVRGIRERRRRVDEALAAVGATGFANRPVGLLSGGEQQR
                     LRVAQALVGDPTVLLCDEPLLSLDLAHQRAVSTLIDARRRAADTAVLFVTHEINPVLPL
                     VDRILYLVDGHFRIGLPEEVMTSETLSQLYGADVAVVRVRGQIHVVGAHSDLCEDNPHH
                     HLAEH"
     gene            complement(18475..19446)
                     /locus_tag="BLS56_RS27470"
                     /old_locus_tag="SAMN05216174_11978"
     CDS             complement(18475..19446)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028570.1"
                     /locus_tag="BLS56_RS27470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11978"
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="WP_091456706.1"
                     /transl_table=11
                     /translation="MTSRPRRSGTALTGLATLTLLGAAACGDSPSTPAGPAADNKISVV
                     ASTNVWASVAQAVGGDAVTVKAILSDPGADPHGYEAKPSDATAFEGAKVALSNGGGYDD
                     FFTGLADTAGKDARKIVAFDLSGKGKEEEGHESEAPDADGHAHEVNEHVWYDLPTVRKV
                     ADKLAEELTAAAPDKKDVFTANATAFGGKLDELAKRAAEIGAAKPGAKVVAPEPVAGYL
                     LETAGLDDVTPEAFAEAIEEETDPPAAAVAETEALVTGKQVAAVVYNEQTETPITEQLK
                     GKATAAGVPVVGVTETLPEGATGYLDWMSKQVDALAGAVAKA"
     misc_feature    19487..19502
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    complement(19491..19502)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            19605..20705
                     /locus_tag="BLS56_RS27475"
                     /old_locus_tag="SAMN05216174_11979"
     CDS             19605..20705
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441636.1"
                     /locus_tag="BLS56_RS27475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11979"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_091456709.1"
                     /transl_table=11
                     /translation="MARSMHVRRPATLASLAAELGVSRTTVSNAYNRPDQLSPELRRRV
                     LETARRLGYPGPDPVARSLRTRKAGAVGLLLTENLSYAFRDPAALGFLEGLALACEGAG
                     QGLHLVPVNPEREDVAAVHRAGVDGFVVYSVPDDDPHLAAVLSRPVPTVVADQPTVEGV
                     DRVGIDDKAAITALADRLIALGHRRIGVICMRLARDRNDGFVSVDRQHSAHFHVQRSRL
                     AGLQGAFGAVGVDWARVPVVERFDHSTASGASAAAQLLDADQDVTALICTSDILALGAL
                     TEAKRRGLRVPQDLTVTGFDGIPDGERVGLTTVRQPVLEKGRAAGKLLLASVDPTRPRE
                     ITLDTELVLGSTSAPPRTADERWFGP"
     misc_feature    19827..19829
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20706..21398)
                     /locus_tag="BLS56_RS27480"
                     /old_locus_tag="SAMN05216174_11980"
     CDS             complement(20706..21398)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS27480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_11980"
                     /product="hypothetical protein"
                     /protein_id="WP_139191025.1"
                     /transl_table=11
                     /translation="MMEPSGPLPKGVYLRRRILAVAGTAFGVVVLIWLIDGLIGDQHDL
                     PPGAAAVADSGPTSSPPSTSSSPPTASTTSDSPPAATSTETSTTPPPPPPPDPSEPCPD
                     ASVAVTAELGAPTYRVGQKPVLRLVVANTGPHPCTRDIGRAQRELVVTGPDGATRLWSS
                     NDCYAAKGEHWHVLAPGERHDFDLTWAGRTSAPGCPPTRTAVPPGDYLVTAKLGPLAGP
                     GVPITITP"
     misc_feature    complement(21489..21502)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.03"
                     /tool="antismash"
     gene            21570..22061
                     /locus_tag="BLS56_RS27485"
                     /old_locus_tag="SAMN05216174_11981"
     CDS             21570..22061
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819008.1"
                     /locus_tag="BLS56_RS27485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_11981"
                     /product="carbonic anhydrase"
                     /protein_id="WP_091456762.1"
                     /transl_table=11
                     /translation="MTAIDDLLQRHIDGPDHGAPEVPTPVPNLHLTIVTCMDARIKVFD
                     VFGLRHGEAHILRNAGGIVTDDVIRSLSISQRKLQTREVIVMQHTLCGLSTFTDDEFRD
                     SVAEDTGLRPPWAVEAFREVKDSVRQSVERVRRSPFVPHTGNVRGFVYDVQTAALTEVL
                     "
     misc_feature    complement(22467..22478)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 ggcacaccgt cgccgccgtg tccgcggtct cgcgcgagtc gctgcgccgg gcagacgacc
       61 tgctgcccga cgtcgccatc gccccgccgg acgaggtcgc ccggggcgcg gaactcgtgc
      121 tgctcgccct gcccgacgac gccctgcccg gcatggtccg cgggctcgcc gccgccgggg
      181 cgctggggcc gacgcagatc gtcgtgcaca cctccggcgc gcacggcgtc gatgtgctcg
      241 cccccgccgc cgaactcggc gcgctcggct tggcgctgca cccggcgatg acgttcaccg
      301 gccgcccgga agacctccag cgcatcgcgg cctgctgctt cggggtgacc gcggccgacg
      361 gcgacgaggt ggcctggaac gtggccgagg cgctggtcgt ggagatgggc gcggagccgg
      421 tgcgcatccc cgaagccgcc cgcccgctct accacaccgc cctcgcgcac ggcgcgaacc
      481 acctggtcac cctggtcgcc gaggccgccg acctgctcgg ctcggcgggc atcggcaccc
      541 cggagcggct gctcggcccg ctgctttccg ccgccctgga caacgcgctg cgccacggcg
      601 accgcgcgtt gaccgggccg gtggccaggg gcgacgcggg gactgtccgc aaacacgtcg
      661 gcgtgctcgc cgagcacgcc cccgacatgc tgcccgccta ccgggcgctg gcctcgcgca
      721 ccgcccgccg ggccgtggag gccggtctgc tgcgcgccga cctgctgccg gacgtggccg
      781 ccgccatcga ggaagagacc ccatgacccg gttcaccgca gggaagctgc acgtccacac
      841 ctcgccggag cagctggcga aggtcacccg ggcgctgcgc gccaccggcc gcaagatcgc
      901 gttcgtgccg accatgggcg cgctgcacgc tggccaccgc gagctgatga gccgcgcccg
      961 ccgcatcccg aacacggtgc tggtggcgtc gatcttcgtc aacccgctgc agttcggcgc
     1021 gggcgaggac ttcgaccgct acccgcgccc cctcgacgcc gacctggccg cctgcgagga
     1081 agagcgcgtg gagctggtgt tcacgccagc gcgggaagcg ctgtacccgc cggacgcgca
     1141 ggtcaccgtc cacgccggac cgctgggcga ggagctggaa ggcgcggccc gccccgggca
     1201 cttctccggt gtgctgaccg tggtcgcgaa gctgttcaac atcgtgcgcc ccgactacgc
     1261 gctgttcggt gagaaggact accagcagct ggtgctgatc aagaagatgg tgcgcgacct
     1321 ggacatggag ccgcacatca tcggagtgcc cacggtccgc gagaccgatg ggctcgcgct
     1381 gtcttcccgc aacgctttcc tcgacgccga tcagcgcgcc gccgccgtgg cgctgtccgc
     1441 cgccctcacc gcgggccagt acgcgggccg ggaaggcgag caggccgtgc tcgcctcggc
     1501 ccgcgacgtc ctggcccgca cccccgaact caaggtcgac tacgtcgccc tgcgcgaccc
     1561 cgacctcggg cctgcgcccg agcgcggcga cgcgcgcctg ctggtggccg ccaagctcgg
     1621 cgacacccgc ctcatcgaca acgtcccggt gctgctcggc aggccggacc tggcccagca
     1681 cggttaagga aaggtgccga gatgttccgc acgatgctca agtcgaagat ccaccgggcc
     1741 accgtcaccc aggccgacct gcactacgtg ggctcggtga cggtcgaccc gatcctgctg
     1801 gaggcggccg acctgcttcc cggcgagcag gtggccattg tcgacatcac caacggcgcc
     1861 cgcctggaga cctacgtcat cgagggcgag cggggcagcg gggtgatcgg catcaacggc
     1921 gcggcagcgc acctggtgca ccccggcgac ctggtcatcc tgatctccta cggcctgatg
     1981 gactccgcgg aggcggccgc gtacgtgccg aagatcgtgt tcgtggacgc ggacaacagg
     2041 atcgtccacc tcggcggcga cgccgggcac gcgcctgcgg actcgggcct gcgcagcggc
     2101 gcggtcaccg ccgacccgcc cgccgagacc gccgacgccg ccaagctgga cgcgctgctc
     2161 gcccacgaga gctgagccgg gcgtgctgct caccatcgat gtcggcaaca ccaacatcgc
     2221 actcgggctg cacaccgacg gcgacctgct gcgcgactgg cggatgcgca ccgacgccag
     2281 gatcaccgcg gacgaactcg cgctcaccat gcgcggcctg ctcggcgagc acgccgaccg
     2341 cgtgaccggc atctcggcgc tgtccaccgt ccccgcggtg ctgcgcgagc ttcgggtcat
     2401 gctcggccgc taccacccgc gcgtgccccg ggtgatcgtg gagcccgggg tccgcacggg
     2461 cgtcccgctg ctggtggaca acccgaagga ggtcggagcc gaccgggtga tcaacaccct
     2521 ggcggcgcac cacctgttca gcaccgcgtg cgtcgtggtc gacttcggca cctccaccaa
     2581 catcgacgtc atctccgcca agggcgagtt cctcggcggc gtgttcatgc ccggcatcga
     2641 gatctccgtg gacgccctcg ccgcccgcgc cgcggccctg cgcaaggtgg agatggtccg
     2701 gccccgctcg gtcatcggca agaacaccgt cgaatgcctc cagtcgggca tcatgttcgg
     2761 cttcgcgggc caggtcgacg gcctggtcac ccgcatctcc cgcgaactgg agcgcaccgg
     2821 ccaccagggc ccggtcaccg tgatcgccac cggcggcctg gccccgctgg tcgtggacga
     2881 gtccgacacg atccagcacc accgcccgga cctgaccctg atgggcttgc gcctggtctt
     2941 cgagcgcaac tcccgctgag tcttaccgcc ggatcgcgcg taccacgctg gtgatcagcg
     3001 ggcggtcgaa ctcgcccgcc gaggtctccg ggcgggacca caggtaggtg cggacccggt
     3061 cgaagacctg ggcgcgttcg gtggcgtcgg ccacggagat ctgggagtgg gtgccgaggg
     3121 tggccagcag ggactccacc gtgcggcgct ggcggtgcgg gaacgtcttc agctcgtgcg
     3181 gttcgagcag gtcgtggctg ggcacgtcca ccttcacccg ctgcacctcg ccgaggctgg
     3241 tcgccgtgag ctcggccagg cccgcgaccc agtcgaccgt caggtcgtcg tggttccaca
     3301 gggcgccgaa gacgccgccg gggcgcagca cgcgggtgat ctcggtgagg gccttgtcgg
     3361 tgttgaacca gtggaaggcg tggccgacca ggaccgcctc gaccgaggcg tccggcagtg
     3421 ggatgtcctc agccgagccg tccagcgcgg gcacgtcggg gatgcggcgg gtcagctccg
     3481 cgcgcatggc ctcgtccggc tcgacggcgg tgacctcaag gccgaaggcg agcaggccct
     3541 cggtgagccg cccggtgccc gcggcgaggt cgagcacccg catccggtcg ccgatgaccc
     3601 attcgatcgc ctcggccgga tagccggggc ggtgctgggc gtaggcggcc gcattggcgc
     3661 cgaaagaact ggcccgcttg gcgaacaact ccgactcgtc catggtcgaa accgtatccc
     3721 tgtcggccgc ggataccggt ttgggtcgcc gccggggttc tccgtaccct ttgcccgtga
     3781 ctgaagagct gcctgactcc ccgaccggcg acgacctgcc cgagcagatg cgcatccgcc
     3841 gggagaagcg ggagcggctg ctcgccgccg gtgtcgagcc gtacccggtg gaactgccgc
     3901 gcacgcatac cctcgcgcag gtccgcgagg cgtattccga tctgccgacc gacaccgcca
     3961 ccggcgacaa ggtcgcggtc accgggcgcg tgatgttcgt gcgcaacacc ggcaagctct
     4021 gcttcgcgac cctgcgcgaa ggcgacggga ccgaactgca ggcgatgctg agcctggaca
     4081 aggtcggcgc ggacgcgctt tcggcgtgga agtccgatgt cgacctcggc gaccacgttt
     4141 tcgtctccgg cgaggtcatc acctcccggc gcggcgagtt gtcggttctg gccgacgagt
     4201 ggcgattggc ggcgaaggcg ctgcggccgt tgccggtggc gcacaaggcg ctcagcgagg
     4261 aagtgcggat aaggcagcgc tatgtcgacc tgatcctgcg tccgcgcgcg cgggagaccg
     4321 tccgcaaccg cgcgggtgtg gtgcgttcgc tgcgtgagag ttttcactcg cgcggtttca
     4381 tcgaggtcga gacgccgatg ttgcagaccg tgcacggcgg cgccgcggcg cgcccgttca
     4441 gcacccagtc gaacgcgatg gacatggagc tgttcctgcg gatcgcgccg gagctgtatc
     4501 tcaagcggtg cctggtgggc gggctggaga aggtcttcga gatcaaccgc aacttccgca
     4561 acgagggcag cgattccacg cattcgccgg agttcgcgat gctggagtac tacgaggcgt
     4621 atgcgaccta tgacaccaac gcggcgatga cccgcgcgct ggtgcaggag gccgcggagt
     4681 ccgttttcgg ctcgcaggtc gtcacccttg acgacgggtc ggagtacgac ctgtccggtg
     4741 agtggacgac gctgacgatg tacgggtcgc tttccggcgc gctcggcacg gaaatcaccc
     4801 cggacacccc cgctgacctg ctgcgcaagc actcggtggc gctcggtttg gagctggacc
     4861 ccgcctacgg gcacggcaag ctggtcgagg agctgtggga gcacctggtg ggcgaccacc
     4921 tgcacgcgcc gacgttcgtg cgggatttcc cgctggagac ctcgccgctg acccgccagc
     4981 accgcaccga gcgcggggtg gccgaaaagt gggatctcta cgtccgcgga ttcgagctcg
     5041 cgaccggata ctccgaactg gtggacccgg tcgtggaacg cgaacggctg gaggatcagg
     5101 cgcggctggg cgcggcgggc gatgacgagg ccatgcgcgt cgatgaggac tttctgcgcg
     5161 cgatggagta cggaatgcca ccaagtggcg gtgtgggaat gggcatcgat cggctgttga
     5221 tggcgctcac cgggctcggc atccgggaga ccatcctctt cccgctggtc cgtcccgaat
     5281 gacccgttcg ggtatccggt actaacgcaa tccgcgagat ttgcgctaac ctgctgctga
     5341 cagtattcgc accagtggcc ggaacgctca acgtgagagc tcttgcgagt cgctcatcgg
     5401 gcaggcacat tcaagcggca aggaggcgca ggtggcgcag aaggtcacgg tttcgctggt
     5461 ggacgacctc gatggctccg aagccgagga gactgtccag ttcgggttgg atggcgcgtc
     5521 ctacgagatc gatctgtccg gggacaatgc cgataggctg cgcgaggcgc tcgccgactt
     5581 catcgatcac gctcgtcgtt ccggcgggcg caaacgcccg gtcgggaagg ccgcgtccgg
     5641 tcgcgtgccg cgcacggctt ccgccgatcg cgagcagaac caggcaattc gcgagtgggc
     5701 ccgcaagcag ggtatgaagg tctccgaccg ggggcgaatc ccgtcggacg ttctggacgc
     5761 gtacaaccag caggcgtgac gaggtcacta aagaggctgc cgtttgggta ggcagcctct
     5821 tgcgtttccg ctgatcgttt gttaggcgtc ggcaaagtgt ggaagtgtcg ccgcgcgaaa
     5881 tcagtttttc cggcacactc tggggcaggt ttggcacgtg ccctgtcccg cttcgagcag
     5941 gtagtggaag cagcagctct cccgccgccg cgtccaccgc gtcggcccgc cgctctcggc
     6001 cagggggcgc agcgtggagt ccgaggtgag cggggccggg ccgtccgcga gcacgagcgc
     6061 ggcgtcgagc acgccagcgc cctcgtcgcc gccgtagcgg cccgcgagcc acagcgagtt
     6121 gtccagcacg tcggtggccg ccgcccagag catccgccga cccagccgca cctgcggcgc
     6181 gaacacctcg acaaagcggg ccgcgtgcgc ggtgaaccgc ccgcgcagga ccgcggccag
     6241 cgcccgctcg tcggacacca cggtcgcctc cggggtcccc gcggccgggt cgtcgggcag
     6301 gcagacgaac cgcggcgaca ggaccgcgat ggcgtccggg tgcggccgcg gctgggccat
     6361 ccggaaggcc aggtcggcgg gccgcagcga cgggacgcgg cgctcgtggt ggaacagcag
     6421 gcccgcgacg tagcccggga cggtcaggta ccagttcatc acgtagcccg cggtcgtacg
     6481 ttcgggtgaa tccccgtacg tctcggtcag ccagctggcg agaccttcac gccatcgggc
     6541 gaatccgtcc ggcatggcga ggaagtcggc gcaccgggtc caccgcgagc ggtcctccgg
     6601 cagcccgaac cgcaccgtcg cgcgggcctg ccgcgggttt acccgatcga gtgaatccgc
     6661 gaggtagccc tgccggtccc tgaggcctgc ctcgatgcgg tatccggccg tcatcgccgc
     6721 ctaccttccg cgcatcggag gcacacgttg ggccacatgg gtgcctcctt actgggctgt
     6781 ccgggtagtg aggattgcct taccttaccg aatctcgctg acatccgtca gacggatcgc
     6841 ccgttgggaa gcgcacactt gtgggtggcg gagtgttcgc gctcagcgga cagggcgcgt
     6901 cttgcggaat ccgaatgcgc cgtcgcacgt tgggtatgac gaaagggacc accgtcaggc
     6961 cgaggcggca cgggtccggt cgcaactggc acgccagtgc cggggccggg cctactacag
     7021 tggtctcacg gtgctgaatc cacgcgaagg atgtggagaa gggccgccgg cgcagcagtc
     7081 agggagtgcg aatgttcgag aggttcaccg accgcgcgag gcgggtggtc gtcctggccc
     7141 aggaagaagc caggatgctc aaccacaact acatcggcac cgagcacatc ctcctgggct
     7201 tgatccacga gggtgagggt gtcgcggcca aggcgctcga gtcgttgggg atcgcgctgg
     7261 aaggcgtgcg gcagcaggtc gaggagatca tcggccaggg gcagcacgcg cccagcgggc
     7321 acatcccctt caccccgagg gcgaagaagg tcctggagct gtcgctgcgc gaggcgctgc
     7381 agctgggcca caactacatc ggcaccgagc acatcctgct cggcctgatc cgcgagggcg
     7441 agggcgtggc cgcccaggtg ctggtcaagc tcggcgccga cctcaaccgg gtccgccagc
     7501 aggtcctgca gctcctgtcg ggctaccagg gcggcaagga gtccaccgag accggtggcc
     7561 gcggcgaggg caccccgtcc tcctcgctgg tgctcgacca gttcggccgc aacctgaccg
     7621 cgtccgcccg cgagggcaag ctcgacccgg tcatcggccg caccaaggag atcgagcggg
     7681 tcatgcaggt gctgtcccgc cgcaccaaga acaaccccgt cctcatcggc gagcccggcg
     7741 tcggcaagac cgccgtcgtg gaggggctcg cgcagatggt cgtcaagggc gaggtgcccg
     7801 agacgctcaa ggacaagcag ctctacaccc tcgacctcgg ctcgctggtc gccggttccc
     7861 gctaccgcgg cgacttcgag gagcgcctga agaaggtgct caaggagatc aagacccgcg
     7921 gcgacatcat cctgttcatc gacgagatcc acaccctcgt cggcgcgggc gcggccgagg
     7981 gcgcgatcga cgcggcgtcg atcctcaagc cgatgctggc ccgcggcgag ctgcagacca
     8041 tcggcgcgac cacgctcgac gagtaccgca agtacgtcga gaaggacccg gccctggagc
     8101 gccgcttcca gccgatccag gtgggcgagc cgtcgctgga gcacaccatc gagatcctca
     8161 agggcctgcg cgaccggtac gaggcgcacc accgcgtcac gatcaccgac gccgccctgg
     8221 tctcggccgc gacgctggcc gaccggtaca tcaacgaccg gttcctgccg gacaaggcga
     8281 tcgacctcat cgacgaggcg ggcgcgcgga tgcgcatccg ccggatgacc gcgccaccgg
     8341 acctgcgcga gttcgacgag aagatcgccg acgtgcgccg ggagaaggag tccgcgatag
     8401 acgcgcagga cttcgagcgg gccgcgaagc tgcgcgacac cgagaagcag ctgctgggcc
     8461 agaaggccga gcgggagaag cagtggaagg acggcgacct cgacgtcgtc gccgaggtgg
     8521 acgacgagca gatcgcggag gtgctggcca actggaccgg catcccggtg ttcaagctca
     8581 ccgaggagga gacctcccgc ctgctgcgca tggaggacga gctgcacaag cggatcatcg
     8641 gccaggaaga cgccgtcaag gccgtctccc aggcgatccg ccgcacccgc gcgggcctca
     8701 aggacccgaa gcggccgtcc ggctcgttca tcttcgccgg tccgtccggt gtcggtaaga
     8761 ccgagctgtc caaggcgctg gcgaacttcc tgttcggcga ggacgacgcg ctcatccaga
     8821 tcgacatggg cgagttccac gaccgctaca ccgcgtcgcg gctcttcggc gccccgcccg
     8881 ggtacgtggg ctacgaggag ggcggccagc tcaccgagaa ggtgcggcgc aagccgttct
     8941 cggtcgtgct gttcgacgag atcgagaagg cgcaccagga ggtctacaac accctcctgc
     9001 aggtgctgga ggacggccgg ctgaccgacg gtcagggccg cacggtggac ttcaagaaca
     9061 ctgtgatcat cttcacctcc aacctgggca cccaggacat ctcgaaggcg gtcggcctcg
     9121 gcttcaccag cggcaacgac cagggctcga actacgagcg catgaagaac aaggtcaacg
     9181 acgagctcaa gaagcacttc cggcccgagt tcctcaaccg catcgacgac atcatcgtct
     9241 tccaccagct caccgagcag cagatcatca ccatggtgga cctgatgatc aaccgcgtcg
     9301 agacgcagtt gaagaacaag gacatggcca tcgagctgac cgacaaggcc aagaagctgc
     9361 tggccaagcg cggcttcgac ccggtgctgg gcgcccgccc gctgcgcagg acgatccagc
     9421 gcgagatcga ggaccagctg tcggagaaga tcctgttcgg cgagatcgag gcagggcaga
     9481 tcatcatcac cgacgtcgag ggctgggacg gcgaagaggg cagcgcggac aaggcgaagt
     9541 tcgtcttccg cggcgagccc aagccgaccc gggtgccgga ctcgctgccg gtcgagctgt
     9601 ccgcgcccag cggcggcgcc gagtcgggcg agggttccga gcccaccgag tgagctagcg
     9661 gcaagcacga cgtgaaggcg gtctcccctc tgggggaggc cgccttcgtc gtttctgagc
     9721 gcgaaaaaga atcaccgatc cagcgtcttc gctggagaga gtgaaaatcg ccgatgaaac
     9781 acgtcaaacg ggtggttctg tcgtcaattt gttccacaga acgtggcact cttgcccgat
     9841 tgggcgacgt gctgtcacgc ggttggccga gtcggaatcc ccggattggc ggatagcgcc
     9901 cgacggtaga tcgtgaggga atgttgcggc gtcgtaaaag cagcgtctgc ggatttccga
     9961 tcaaaaccca cgatggtcga cttcgccgga ggggtgcgac atggatctac agtatgaggc
    10021 gttctgcttt gtcgaccccc ttttcttcga tcagcctcga cagacggcca ccacattaaa
    10081 cgggttctcg acaagattgc ccgctccgca tgagggctgg gtcgacggag tggcgggaat
    10141 ctggcggatg ctgcgccccg ttggtgtgac tctgcctggt cagggctgga agattcatgt
    10201 ctcggccacc ctcggcaacg ccgagcgggt gctgtcggcc gtgcacgcgc actgcctcga
    10261 ccgggggctc gcctacaagc acctgctcag cccgagcgtg ctgctcgcgc gcaattccaa
    10321 atacgcgccc cgctccggca gtggaaaact tgtcaccatc tatccggtgg acgacgacag
    10381 tttcagccag gtgctggccg aattgtcgac attgttggac ggcgaggcag gcccgtacat
    10441 cctcagtgac ctgcgcattg gttccggacc gctttatgtc cgctatggcg gcttcgccga
    10501 gcagtgggtg gagatcgacg ggacccgggt gctcgcggtg cgcacaccgg acggcacgct
    10561 cgtgccggac aaacgcgagc ccacgttctc ggtccccgac tgggtcacgg tcccggactg
    10621 cctggccccg cacatcgccg cccgcaaagc gggcaacccc gacgacttcc cgtaccgggt
    10681 caccgcgtcg atgcacttct ccaacggcgg cggcgtctac cgggccaccc ggaagtccga
    10741 cggagccgag gtcgtcctca aggaggcccg cccgcacgcc gggctcgacc gggacggcgt
    10801 ggacgcggtg gcgaggctgc gcggcgagca cgacatcctc gtccgactcg ccgacgtcga
    10861 cggcgtcccc gccgcgcacg acctcgtcac ggtctgggag cacacgttcc tggccatgga
    10921 gccggtcgcc gggcagtcgc tcgggtcgtg gctggcccgg acgtacccgc tcacccggca
    10981 gcacgcgagc gacgaggccg tcgccgagta caccgagcgc gccctcactg tgctcgggcg
    11041 ggtcgaggac ctgctggcgc gggtgcacga gcgcggcgtg atgttcggcg acctgcacgc
    11101 gctcaacatc atcatcgatg acgacgaccg ggtctcgctg atcgacttcg agatggcctc
    11161 ggccgcggcc gaaccgggca gacccgcgct cggcgcaccg gggtttcgcg caccggccgg
    11221 gcgcacgggc ttcgacgtcg accggtacgc gctggccgcc ctccgattat ggatcttcct
    11281 gccgctcaac gccctgctcg aactggcccc cggcaggctc gacgccctcg tggacgtcat
    11341 cgagcgccgc ttccccctcc cgcccggcta cggcgacggc atccgccgcg agctacggca
    11401 gaccgaccag gctgagaccg accaggcggc gaccgccccg gcggctaccg aactcgaccg
    11461 gcccgacccc gactggggcc aggtccgcaa agccctcgcc gtggccatcc tcgccagcgc
    11521 caccccggag cgggacgacc ggctgttccc cggggacatc gagcagttcc gggtgggcgg
    11581 cgcctgcttc ggctacggcg cggcgggcgt gctgcacgcc ctcgacgccg ccgggaccgg
    11641 ccggtatccc gagcacgagc gctggctgat cgacaccgtc cgccgcacgc cgcccgcccg
    11701 acccggattc ttcgacggcg cgcacggcat cgcgcacgtc ctggagaacc tcggccacca
    11761 cgaggacgcc gccgccgtgc tcgacggcgc ggacaacctg gtcgcgcaga cccgggacca
    11821 cagcctcgac ggcgggctct ccggaatcgc gctgaacctg ctgcacttcg cgggcacccg
    11881 gcacgaccgg gacctgcgga cccgcgccca cggcatcggc gaccggctcg ccgacgccct
    11941 gcgcgccgcc acaccgagcc cgttcgcccg cgcgggcctg ctcaacggct ggtccggggt
    12001 cgcgctgctg ttcctgcggc tgcacgacga caccggcgac cgcggctggc tcgacctcgc
    12061 tgagcaggcc atatcccgtg acctcgacga gtgcgtgacc accgacgacg gcgttctcca
    12121 ggtgcgcgat cagggcgccc ggaccctgcc ttacctgtcg atcggtagcg cgggaatcgc
    12181 cctggtggcc gaggaactgg ccgcccgccg ccccgactcg gcgatcctgg aacgccaacc
    12241 ggacctgctg cgcgcctgcc acggcgagtt cgtcatccac cccggcctgc tcttcggccg
    12301 gtgcgggctg ctggtcaccc tcgccgcggc ccagcggcgg gcggcggacc ccgagcgggc
    12361 cgaggtgatc ggcaggcacc tggccgcgct gggctggcac gccgtcccgc acggcgacgg
    12421 cggcatcgcc atgccgggaa accagttgct gcgcctctcg atggacctcg ccaccggcgg
    12481 cgcgggcgtc ctgctcgccg tcaccgccac cctcgacggc cacggccggg tcctgccctt
    12541 cctaggcgat gccccgcacc ccccgatctc cggtcatccg gccggtgaga aagaaaggaa
    12601 cacatcatgg agatgatcct gaacctccag gagctcgagg cccccaacga gctcagccac
    12661 aacgacggcg gcggacacgg cggcgcgagc aacctgagct tgctcgcctc ctgtgccaac
    12721 agcaccgtca gcctgctgac ctgccactag gtaagtaggc aagcgggagc ggcgcaggac
    12781 tggtgcgccg ctcccgcttc cattctggac tgttggcatt ggcgcgagaa agggccggac
    12841 gtgggcgttc ccggcgatcg gctgctccgg tcgatggtgc gccgcgaccg cggctgggtg
    12901 gcgctgctgg tcgcgaccgc cctgatcgcc acggccgcgg ggctgctgct gcccgccgcg
    12961 ctcgccgccg cgctcgacag cgtgcgggcg ggaggctcgg ccgtgctgtg ggtggtcgtg
    13021 ctcggcgcgg tcggcatcct cgccgaagtc gcgggcgtgg tcctgaccgc ccgggtcacc
    13081 gcgaacgcca ccgcgcgcct acgcgccgat cttggcgacc acctggtccg tctcggcacg
    13141 cactcggact tcgctgacgg tgacgcggta agtcgcatta ccggggactg cataggcgcg
    13201 gggcagatcg ccgcgcttgc cgtgcaactg ctcggggcgc tgctgatgtc cgcgggcgcg
    13261 atcaccgcgc tggcgctgct ggactggcgg ctcgccgcgg tgttcttgtg cgcggtgccg
    13321 ctcgccctgc tgctcgcgcg ttcccacctg cggctgacag ccgcggatgt gcaggcgtac
    13381 caagaggttt ccggcgaact cggcgcccgc ctgctcgacg cggtggcagg cctgcgcacc
    13441 atcaccgcag cgggtgtcgc cgaccaggag acggcccgcg tgctgcggcc cctgcctcgg
    13501 ctgagcgcgg cgggcgcggg catgtggcgc acccaggcgc ggatggtctg gcgggcgggc
    13561 ctgctcatgc ctgccgtgca ggtcacggtc ctggccgcgg ccgggttcgg cgtgcttacc
    13621 ggacggctca ccatcggcga catgctcgcc gcactcgggt acgcggtgct cggattgggc
    13681 gtggtgcgcc agatccccct gctcacaacg ctgtcacggg cccgctcctg cgcgagccgg
    13741 atagccgccg tgctcgacac ccccgcggaa gacagcgcgg gtcaggcgct tccgccggga
    13801 ccgggcgtgg tcgaggtgcg ccgggtcggc gtcgacggcg cgctgtccga ggtcgacttc
    13861 gtgatcccgg ctgggaccgc ggtggcggtg gtcgggcggt ccgggtcggg caagtcggtg
    13921 ctggcgtcgg tcctcgcggg actccggcgg cctgaccgcg gtgaggtgcg gttggacgga
    13981 gtgccgctgt ccgctgtggc cgacgcggac ttgcgggcca ctatcggctg cgcttttgaa
    14041 cggcctgctc tgcttgggtc gagcgtccgc gcggcggtgg cttacggcgt gacggcagac
    14101 gaggcggcgg tgcgtgcggc ctgtcggttg gcgcaggtgg acgacttggt ggttcgcctt
    14161 cctgacggtt acgcgacccc gttgtcccgg acgccgctat ccggtgggga agcccaacgc
    14221 cttgggctgg ccagagcggt cgttcgcact ccccgcttgc tggttcttga cgacgccacg
    14281 gcgagcctgg acacggttac cgaggcgcag gtggaggccg ccctcgccgc tcggccgcac
    14341 acccgcgtca cgatcactca ccgcgcgggt gtcgcgagcc gcgcggacct ggtggtgtgg
    14401 ttggacggtg ggcgggtgcg tgggttcggg ccccatgacg ttctctgggg ggagtccgct
    14461 taccgcgcgg tgttcactga agaggaggca cggtgaatac cgctgtcggt gcttcgtggg
    14521 gttggctcga tggggtggag tggtttctcc ggggccccta cgaaggaaga tcgccgtgtg
    14581 aaagacgggt gggaagcctt cggccgcaca cgtgcggagc cagcttggcg atcttccttc
    14641 tcccccgaag aaaccactcc accccatcga gcgcctggca ggggcgggtt tcgtcgccag
    14701 gtgggctggg tcgctgtccc tgttccagtt gtcgaaccaa tccacttatc tgccacgccg
    14761 catccacagt caggtaccgc cacttggcgg ccgctcgggt ggcgtgccgg gttggcctgc
    14821 tggggggtgg ggcgtggtga ctgtcaccag ggcgtactgg cgggggctcg gcgggcactg
    14881 gcgggcctgg tcggcgctgc ttgcctgctc tttgttagag gcgcttcccg cgtttctctc
    14941 gggcaggttg gttcagcgcg ccgttgatga cgggttcgcc gttggcaggc ttggcgtggg
    15001 gctggcctgg cttgccgggt tcgcggtggc ggccgtggtg ggggcgttcg gggcgcgact
    15061 ggtgtggcag cggcttgggg tggtcatcga gccgctgcgg gacagtcttg tccggctggt
    15121 cgtggggggt gtgctgcacg atccggcgcc accgcgtggc gggccggacg cggctggggt
    15181 ggcgcggatc acgcagcacg tggaggtgat tcgggacgcg acggcggggt tgttggtgca
    15241 ggcgcggggg ctggtggtga ccgtcgtcgg ggcgttggcc ggggtgacgg ccatggcggg
    15301 ggagttggcc tggctggtcg cggtcccggt ggtggccgcg ctggcggtgt tcgtcgcgct
    15361 gctgcccacg ttggcccgca ggcagcgggc actcgccctg gccgacgagc acacggcggg
    15421 cacggtcggc ggggtcctca ccggaatgcg ggacgtggtg gcctgcgggg cgcgggacgt
    15481 ggcggcgggg gaggtgcggg cggctgtccg cgcccaggcc ggggccgcgg tccgaatggc
    15541 caccgcggcg gcctcacgga ccctggtcat cgcggtcggc gcgttcctgc cgttggtgct
    15601 ggttctcctg tcggctcccg ccgcggtgag ccacggcagc cttaccgccg gggcggtact
    15661 cggcaccctg gtctacctca ccggcaccct cacccccgca ctgcacagcc tcgccgcgac
    15721 cgcgagcacc gttgtcctcc gactgctagt cgccctccgc agactggacg aagtccaccc
    15781 cccacccccc accgtcggca ccgagaagcc cgcccacggc gtcatcaccg tccgagccct
    15841 gacccaccgc tggggcgagc acgccgaacc ggtgctgcgc gacctcgatc tggacctggc
    15901 ccccggcgac cacctggctg tggtcggccc cagcggcatc ggcaagtcca ccctcgccgg
    15961 aatcctgacc ggcacactcc tgcccaccag cggcgaagtc cgcctaggcg gtgtccccgt
    16021 caccgacatc gacccggcgc accgacatcg cctgatcgcc ttcacccctc aggagtccta
    16081 cattttcgcc gggacagtcc gagagaacct gtccctcctg gcccccaccg cggacgaccg
    16141 ccacctgcaa gccgcggcgg acgcggtcgg cgcggcaaac ctcatccacc gcctaggcgg
    16201 cctctccgcc ctcctagacc acgcaggcgc aggcctatcc gcgggcgaac ggcaactctt
    16261 ggccctgacc agggtctacg caagccccgc caccatcgtc gtcctggacg aagccaccgc
    16321 caacctggac cccccaaccg aagcccaagc cgaacatgcc ttcgccaccc gcgacggcat
    16381 cctgatcgtg atcgcccacc gcctgacctc cgccatccgc gccccccaag tcctgctcat
    16441 ggacggccgc gaaacccacc taggcgacca ccccaccctg ctggccacct cacccgccta
    16501 cgccgccctc atgcacgcct gggccccgct tgcgaacact caacggcacc cccatgatcg
    16561 cgagttatcc acaggcgcgg accgtcctct tccccgcgct gacctgcggc gatagactgg
    16621 agcggggtca gcccccaggg tgggtggggc tttgttgtgg ggctgctggg cggcgaatga
    16681 aggtcgtttg agggcatcgt tcggtctgcc gcactcgctc gcctgccaac cggcacccac
    16741 tccaccccat cgagcggacc ccgcggaacc aggcaaccta agcaaacgca gcgcggcgaa
    16801 cgcggctgat cacccagcac accaggtaga tcaggaacga gatcgccgtg acgaacgcgc
    16861 tcaccggagc ccccggcgca agcgacagca cgattccccc aacggccgac acctcggcga
    16921 acagaatcgc cagcagggtc gcccgcaggg gactggcggt cacccggcaa gccgcggcgg
    16981 caggcgtgac catcagcgcc agcaccagca gcgatcccac cgtgcgcacg cccagcgccg
    17041 tggccacgcc gaccaggacc gcgaacacca gcgccagccc ggtcgtcggc accccgcggg
    17101 cgcgcgccac atcggcgtcc acgctggcga acagcagcgg ccggtacagc aacgccagca
    17161 cgacgaaaac gcctaccgcg cagccggtaa gcagcgcgat gctggcgaag tcttggccga
    17221 cgatctgccc cgtgagcagg ccgaacttgt tcgacgcgcg acctttgtac agccacagca
    17281 tgagcacgcc catgccgagg ccgaacgcga ggacgacgcc gatcaccgag tcgtagtcgg
    17341 agcttcggcg ggacagcagg cccagcacga gcgcggcgac gatggctccg gcgagggcgc
    17401 cgttgccgac ttcccagccg agcaggaggg cagccgcgcc gccggtgagg gcgagttcgc
    17461 tggtgccgtg cacggagaac gccatgttcc tggcgacgat cagcggtccc aggacgcccg
    17521 cgagcagccc caggatcgcc gcgacgagca gcgcgcccag cacgaagtcc aggctcagca
    17581 gcttcatcgt cagctcgacg tcgaacaggt tgtccatcta gtgctccgcg aggtggtggt
    17641 gcgggttgtc ctcgcacagg tcgctgtggg cgccgacgac gtggatctgg ccgcgcacgc
    17701 gcacgacggc gacgtcggct ccgtacagct gcgacagggt ttccgaggtc atgacctcct
    17761 cgggcaagcc gatccggaag tggccgtcga ccaggtacag gattcggtcg accaggggca
    17821 gcaccgggtt gatctcgtgc gtgacgaaca ggaccgccgt gtccgccgcg cgcctgcggg
    17881 cgtcgatcag ggtgcttacc gcgcgctggt gagccaggtc gagggacagc aggggctcgt
    17941 cgcagagcag gacggtcggg tcgccgacca gtgcctgggc gacccgcagc cgctgctgtt
    18001 cgccgccgga gagcaggccg acggggcggt tggcgaagcc ggtcgcgccg accgcggcca
    18061 gcgcctcgtc cacccgccgc ctccgttcgc ggatgccgcg cacgcccagg ccccagcggt
    18121 ggccgtcgta gccgaggccg acgaggtcgc ggccgcgcag ggccagtgtg gggtcgaggg
    18181 cgcgttgctg cgggatgtat ccgatgcgtc ggttgccctt accgggcggc tcaccggcca
    18241 cgtttaccgt gccgccggaa agcttttgca gtcccaagag gactcgcata agactggtct
    18301 taccggagcc gttcggcccc aggacggcca ggaactcgcc cggacgcacg tccaagtcca
    18361 ggccgtccca caggacgcgg tccccgtagg cgagccgggc gtccgtgagc gacaccgccg
    18421 ccgcgccgcc gggaacgggc ggcgcggcgg gcggtgccgt ggaacgctct accgtcatgc
    18481 cttcgccacg gctccggcaa gcgcgtcgac ctgcttgctc atccagtcaa ggtagccggt
    18541 cgcgccctcg ggcagggtct cggtcacacc gacgaccggc acgcccgccg cggtggcctt
    18601 gcccttgagt tgctcggtga tcggggtttc ggtctgctcg ttgtagacca ccgcggcgac
    18661 ctgcttgccg gtgaccagcg cctcggtctc ggcgacggcg gccgcgggcg ggtcggtctc
    18721 ctcttcgatg gcctcggcga acgcctcggg ggtcacgtcg tccaggcccg cggtctccag
    18781 caggtagccc gcgacgggct cgggggcgac gaccttcgcg cccggcttgg ccgcgccgat
    18841 ctcggcggcc cgcttggcga gttcgtcgag cttgccgccg aacgcggtgg cgttggcggt
    18901 gaacacgtcc ttcttgtccg gggccgcggc ggtcagctcc tcggcgagct tgtcggcgac
    18961 tttccggacg gtcggcaggt cgtaccagac gtgctcgttg acctcgtggg cgtgaccgtc
    19021 ggcgtcgggg gcctcggact cgtggccctc ttcttccttg cctttgccgg acaggtcgaa
    19081 cgcgacgatc ttgcgcgcgt ccttgcccgc ggtgtccgcg agtccggtga agaagtcgtc
    19141 gtagccgccg ccgttggaca gcgcgacctt ggcgccctcg aacgcggtgg cgtccgacgg
    19201 cttggcctcg tagccgtgcg ggtcggcgcc cgggtcgctc aggatggcct tgacggtcac
    19261 cgcgtcgccg ccgacggcct gcgccacgct cgcccacacg ttggtcgagg cgaccacact
    19321 gatcttgttg tccgccgccg ggccggcggg ggtgctcggt gagtctccac acgccgccgc
    19381 gccgagcagg gtcagggtgg ccaggcccgt gagtgccgtg ccggaccttc tgggacgcga
    19441 ggtcatgtgc gctctcctgg gtgattggtg gtcgcctcgg tgcgacaatg gaaaccgttg
    19501 tcgtcaccat agcccacctg cgcccatcga tcgggtggcc gcgctaacca gggcgtgacc
    19561 ggaccggact tctgcaattg gttctgaacc gttacggtca gtccatggcg cggtcaatgc
    19621 atgtgcgacg gccggcgact ctcgcgtcgc tggcggcgga actcggggtc tccaggacca
    19681 cggtgtccaa cgcctacaac cggccggacc agctgtcccc ggagctgcgc agacgggttc
    19741 tggagaccgc gcgcaggctc ggctatcccg ggcccgaccc ggtcgcccgc tccttgcgca
    19801 cccgcaaggc gggcgcggtc gggctgttac tcaccgagaa cctctcttac gcgttccgcg
    19861 accccgccgc cctcggtttc ctcgaaggcc tggcgctggc ctgcgagggc gcgggccagg
    19921 gcctgcacct cgtcccggtc aaccccgagc gcgaagacgt cgccgccgtg caccgcgcgg
    19981 gcgtcgacgg cttcgtcgtc tactcggtgc ccgacgacga cccgcacctc gccgccgtgc
    20041 tctcccggcc ggtgccgacc gtggtggccg accagcccac cgtcgagggc gtcgaccggg
    20101 tcggcatcga cgacaaggcc gccatcaccg cgctcgccga ccggctcatc gccctcgggc
    20161 accgccggat cggcgtgatc tgtatgcgcc tcgcccgcga ccgcaacgac ggcttcgtgt
    20221 cggtcgaccg gcagcacagc gcccacttcc acgtccagcg ctcccggctc gccgggttgc
    20281 agggcgcgtt cggcgccgtc ggcgtcgact gggcgcgggt gccggttgtc gagcggttcg
    20341 accacagcac cgccagcggg gcgtccgcgg ccgcgcagct gctcgacgcc gaccaggacg
    20401 tgacggcgct gatctgcacc tcggacatcc tcgccctcgg cgcgctcacc gaggcgaagc
    20461 ggcgcgggct gcgggtgccc caggacctca cggtcaccgg gttcgacggc atccccgacg
    20521 gcgagcgggt gggcctgacc acggtccgcc agcccgtcct ggagaagggg cgcgcggcgg
    20581 gcaagctgct gctggcctcg gtggacccga cccggccccg cgagatcacc ctggacaccg
    20641 agctggtgct cggctccacc tcggcgccgc cgcgcaccgc ggacgagcgc tggttcggcc
    20701 cctgatcacg gcgtgatcgt gatcggcacg cccggtcctg ccagcgggcc gagcttggcc
    20761 gtcaccaggt agtcgcccgg cgggacggcc gtgcgcgtgg gcgggcaccc cggggcggat
    20821 gtgcggcctg cccaggtcag gtcgaagtcg tgccgctcgc cgggcgccag gacgtgccag
    20881 tgctcgccct tggccgcgta gcagtcgttg ctcgaccaca gccgcgtcgc gccatctggg
    20941 ccggtgacca ccagttcacg ctgcgcgcgg ccgatgtccc tggtgcacgg gtgcggcccg
    21001 gtgttggcca cgaccagccg caggaccggc ttctgcccga cccggtatgt cggcgctccc
    21061 agttcggcgg tgaccgcgac tgaggcgtcc gggcagggct cgctcgggtc cggcggggga
    21121 ggtggcggcg gtgtggtcga cgtctcggtt gaggtcgccg ctggcgggga atcagaggtc
    21181 gtggacgcgg tcggcggcga tgaggaggtg gatggcggtg agctggtcgg gccggagtcg
    21241 gcgacggcgg cggcgcccgg cggcaggtca tgctggtcgc cgatcaggcc gtcgatgagc
    21301 cagatgagca cgacgacgcc gaatgccgtc ccggcgacgg cgagaatccg acgccgcagg
    21361 taaacgcctt tgggcagagg tccggatggc tccatcacct cgggaacggt atccgcgccg
    21421 cggcctccga acgccggttt ttcgctcacc cgataggcgg gtctcgcccc gggtggcgac
    21481 acgaacagtg ataattacca aatacgcctt gtgggacaac tgggacacaa ggtccaatca
    21541 gtgatcaaca gaaccaaccg gaggtggccg tgaccgcgat cgacgacctg ctccagcgcc
    21601 acatcgatgg cccagaccat ggcgcgcccg aggtcccgac cccggtgccc aacctgcacc
    21661 tgacgatcgt gacctgcatg gacgcgcgca tcaaggtctt cgacgtgttc ggcctccggc
    21721 acggcgaggc gcacatcctg cgcaacgcgg gcggcatcgt caccgacgac gtgatccgct
    21781 cgctgtcgat cagccagcgc aagctccaga cgcgcgaggt gatcgtcatg cagcacaccc
    21841 tgtgcggcct gtccacgttc accgacgacg agttccggga cagcgtcgcg gaggacaccg
    21901 ggctgcggcc gccgtgggcg gtcgaggcgt tccgcgaggt caaggacagc gtgcggcagt
    21961 cggtcgagcg ggtgcggcgc agcccgttcg tcccgcacac cggcaacgtg cgcggcttcg
    22021 tctacgacgt gcagaccgcc gcgctcaccg aggtgctcta gccgaatcct gtctcgacct
    22081 agactctccg ggtgcccagc ctcgacgtga tcgaagtcct cgactggttc gacgcgaacg
    22141 cccgcgacct cgcctggcgc aagccgggca ccaccggctg gggtgtgctg gtcagcgaga
    22201 tcatgctgca gcagaccccg gtcgcccggg tggagccgat ctggctggcc tggatggccc
    22261 ggtggccgct gccgtcgtcg ctggccgcgg tgagccaagg cgaggtcgtg cgggcgtggg
    22321 gcaagctcgg gtacccgcgc cgggcgctgc gcctgcacgc cgcagccggg gtcatcgccg
    22381 cggagcacaa cgacgtcgtg cccgccgaca tcgacacgct gctggccctg ccgggcatcg
    22441 gggcgtacac ggcgcgggcc gtcgccgcgt tcgcctacgg gcagcgctgc ccggtggtcg
    22501 acaccaacgt gcgccgcgtc gtcgcccgcg cggcgcacgg cgcaggcgac gccggtccgc
    22561 catcgaccac ccgcgacctc gccgacgtcg aggcgctgct gcccgccgac ccggcc
//
