LOCUS       NZ_FMZZ01000004        24283 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinokineospora iranica strain IBRC-M 10403, whole genome shotgun
            sequence.
ACCESSION   NZ_FMZZ01000004
VERSION     NZ_FMZZ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora iranica
  ORGANISM  Actinokineospora iranica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:26:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,202
            CDSs (total)                      :: 6,139
            Genes (coding)                    :: 6,038
            CDSs (with protein)               :: 6,038
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 25 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 7 of 103
            Pseudo Genes (multiple problems)  :: 18 of 103
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 49929
            Orig. end                         :: 74212
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMZZ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24283
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24283
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24283
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14283](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14283)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(579..1844)
                     /locus_tag="BLS56_RS10160"
                     /old_locus_tag="SAMN05216174_10454"
     CDS             complement(579..1844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006236929.1"
                     /locus_tag="BLS56_RS10160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10454"
                     /product="DNA sulfur modification protein DndB"
                     /protein_id="WP_091449747.1"
                     /transl_table=11
                     /translation="MSINVDPRLLSRPQDSSTYLALKTMQGGRAVYSTRVPLLDLPTIL
                     PVPDPNNVDKDNRKVDRLHAKQFGEYLDSKQDWVAPALLARDGGGCTFQKADEEGRVGY
                     LTVPWAIGGIATLRTIDGQHRILGVSIEKQRITDAVSAIDRELARKVSVDKAAKLQAER
                     ERLVGQMTRLKEEYVGLDIYVEPDPIKSQQMFVDVADNAKGISSAVRARFDNYKVANRT
                     LSDVIDHPLLKGRVDAEQDRMTLKNPNLMGAKHVADITRAVIAGAGGRISKKAEQSLTD
                     GEVIEQVKDFLDIISTAFGDLAAVTEDDPEAECKPDELTMSQKLRRTSLLGSVGMLRVL
                     GGVFRELRAGDNPAELDDIAAFFKKLDPHMAAPVTESSIWRTTDAHKDFEPDAFAPIMR
                     TQNIVHLVGVITSWYKKAPATL"
     gene            complement(2022..2285)
                     /locus_tag="BLS56_RS10165"
                     /old_locus_tag="SAMN05216174_10455"
     CDS             complement(2022..2285)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10455"
                     /product="hypothetical protein"
                     /protein_id="WP_139190593.1"
                     /transl_table=11
                     /translation="MWNATPRPGPLKAADVLGPREDVELPGLGIDGVSLEMLNWGTADI
                     TFAFRDVEGQWWRRVSGGEPARVEASVATWRVRSAVESSSDA"
     gene            complement(2304..2597)
                     /locus_tag="BLS56_RS10170"
                     /old_locus_tag="SAMN05216174_10456"
     CDS             complement(2304..2597)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10456"
                     /product="hypothetical protein"
                     /protein_id="WP_091449749.1"
                     /transl_table=11
                     /translation="MAVAVVVLIRDRRLHNKVMTKLRAEQVQQVDAADAARRARQLAEA
                     STVVIEFKPMRRPNSNSMFPGVSISNHGSVPVLEVVVLDMVFTDDEGVRHAD"
     gene            complement(2736..3518)
                     /locus_tag="BLS56_RS10175"
                     /old_locus_tag="SAMN05216174_10457"
     CDS             complement(2736..3518)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10457"
                     /product="hypothetical protein"
                     /protein_id="WP_091449750.1"
                     /transl_table=11
                     /translation="MSTSPAVASEPDGDLTITAADETGFMALMRAMLAHSGLTAGQVAM
                     YAKLPRSTAYRFVSEKNTTLPKHAHQVRAFARGCRLRPEQVEQVMMLWANLREMSTALE
                     IIAPKELVLDAELVDHRPNEQHRDEPVLQRLTGGMGSVAVHGDINIAYNTHHNITNHRY
                     SHSGAQTDNATQDEGASQEGTNQRSGERRRRPFLRDLLDNYRWVLNAVALLSALSMILF
                     AFIALLLVDGVEAYPATAMVLLFAGMTLTVLRLLRPRR"
     gene            complement(3515..3865)
                     /locus_tag="BLS56_RS10180"
                     /old_locus_tag="SAMN05216174_10458"
     CDS             complement(3515..3865)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10458"
                     /product="hypothetical protein"
                     /protein_id="WP_139190594.1"
                     /transl_table=11
                     /translation="MTTRPGDHDGPQYIPGRESEDITATTKPAPGVTDVAAGPAWTWQT
                     VLLVLTLVMSSFVFVYLLLGTGLEVHTAVLVPIGLLAVIVPLVVPTKSGNSLGRRLVRA
                     LTAFADDGQGPR"
     misc_feature    4240..4253
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            complement(4630..5217)
                     /gene="shbA"
                     /locus_tag="BLS56_RS10185"
                     /old_locus_tag="SAMN05216174_10459"
     CDS             complement(4630..5217)
                     /codon_start=1
                     /gene="shbA"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682251.1"
                     /locus_tag="BLS56_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10459"
                     /product="RNA polymerase sigma factor ShbA"
                     /protein_id="WP_091450037.1"
                     /transl_table=11
                     /translation="MDAVFARLKSAAFHELVDASLKGDQEAIGTLFAWINPAIIRYCRA
                     RIGRTGSAFSNADDVAQEILLAVLGALPRYSDDRESFLPFVYGIASHKVADYYRRSGRD
                     RSEPVADVPDTIDHNLGPEQITLRGEMRSRLVRLLDTLAPRQREILVLRLVVGLSAQET
                     ATAIGLTATAVRVAQHRALTRLRGELSAGDWL"
     misc_feature    5179..5188
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(5495..6046)
                     /locus_tag="BLS56_RS10190"
                     /old_locus_tag="SAMN05216174_10460"
     CDS             complement(5495..6046)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019886.5"
                     /locus_tag="BLS56_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10460"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_091449752.1"
                     /transl_table=11
                     /translation="MDAEFQDFFRHAFPKTVAVLRQMGFGLEESADSASEAMIALLTST
                     AEITSPLAWVVKIAIRDASRNAQRAVLGRQKAALAARRDRPKVSEIGSGQLDEVVLDLL
                     MRLSPVRRQVIALYYQGFETYEIADILASKESTIRSHRRHAKIQLSGFVRELRAEVQGE
                     FDEFLTLLQIEEVPTRGQRR"
     misc_feature    complement(6127..6141)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.87"
                     /tool="antismash"
     gene            6605..7684
                     /locus_tag="BLS56_RS10195"
                     /old_locus_tag="SAMN05216174_10461"
     CDS             6605..7684
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024734.5"
                     /locus_tag="BLS56_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10461"
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="WP_228771530.1"
                     /transl_table=11
                     /translation="MNLVDAMEAMVNHTTEQWGLITAAQAKTVGVDGMTLQRAVEAGLL
                     ERVRRGCYLATAATMPKHLQPKAVWLALNPTVPAWERPDLDPDGGVISHSSAALIHGIG
                     DLRADIVEITVPRRRVTREQDVSPRRAELTEDDVELVDGLPVTTVPRTITDHLADHIDG
                     GHVGAMIYHAARRGLVDLDQLANRSGTYARRYGLPRGHGRSLIEYLLAQAGHSLADLVA
                     PNGLVRTSDLRHILEVLPRTTLSLSGTPINAALAQMVESIQGMVPAAGVLENLSVPLTS
                     FARSLPQLSSSHIEGLRRSLSQLDVLNRQAELLRALELPHASAEIARSSSIMAAALAAA
                     GAEAARSAAMPGEDDEDMP"
     misc_feature    complement(6624..6638)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.46"
                     /tool="antismash"
     gene            7684..8601
                     /locus_tag="BLS56_RS10200"
                     /old_locus_tag="SAMN05216174_10462"
     CDS             7684..8601
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020419.5"
                     /locus_tag="BLS56_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10462"
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="WP_091449754.1"
                     /transl_table=11
                     /translation="MDLPAAARRRLNNLARNHARATGQNSTTLVERYLYDRLLARLATH
                     DAEGWLVKGGQALLRRYPHARHTRDLDLLHLTSLSADLDDAVAVLRTAVALDLGDHLHY
                     VYRDTTTASKGGQARRVRFTPYYGRTALNTISVDLVVGHTPLGQPTTRSLQSCVPGLDD
                     GQWPDVHLYPIVDHIADKISAMYERHGPQAIPSSRSHDLVDLLLIILSETIDGTTMHTA
                     LHAEVARRRQRGTMLILPAKFHVPGGQSWSAGYARDARGVTGLARHQTLNEAAGLAAAF
                     ITPLLTATPPGRWTPDHLRWLNPP"
     misc_feature    7690..7692
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8119..8121
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8815..10023)
                     /gene="fxlM"
                     /locus_tag="BLS56_RS10205"
                     /old_locus_tag="SAMN05216174_10463"
     CDS             complement(8815..10023)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="BLS56_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10463"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_228771531.1"
                     /sec_met_domain="PCMT (E-value: 2.3e-48, bitscore: 159.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSMTSTEPEDLRDHMVEHLKDSGHLRSHRIELALRTVPRHLFVP
                     AASVEDAYANKAITIKPGPDRPASCISVPTVVAMMLDQLDPQPGDHVLEIGAGTGYNAA
                     LLAELVGPTGSVTTIDIHPDVTAHARQALDKTGHDQVRVVTGDGALGDPDHAPYDKIIV
                     TVGPWDLPPAWFDQLAPGGTLVVPLHWRGQARSVAFTRTDRGLRATDSRLCGFIPMIGI
                     VPSGEQTGHIVDDVALYWDSDQNIDPAALHEVFTQPATTVWSGASVVANESFDHIWLWL
                     TATEPGACRLAAEPAAIDAGLCRPVFAHRTPAMVEGDSLAYLTKPRPLDQDGERRYELG
                     ATGHGPAGAHLAERLCEHIRHWDSDRTAQPTITAYPADTPAENLPVGGVVIDKRHVRMV
                     VTP"
     gene            complement(10001..11239)
                     /locus_tag="BLS56_RS10210"
                     /old_locus_tag="SAMN05216174_10464"
     CDS             complement(10001..11239)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="BLS56_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10464"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_091449755.1"
                     /sec_met_domain="LANC_like (E-value: 2.9e-43, bitscore:
                     142.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTDPCSPPPEHEPKPGWHQSLSDGAAGLALLHITYAQTGVGDW
                     ATAHRWVTAMTRDPVAAHPDACLFHGAPAVAFVLRTAGQPSYAAALAAIDDHIAKLTRH
                     RLDQAHDRIERGLLPELREFDLINGLTGIGAYLLQTDNTELLRDVLAYLVRLTEPLRVD
                     GQTLPGWWTGNAPADRPDPRWPGGHANLGLAHGIAGPLALLATAVIHGVTVSDHAEAID
                     HFDAALGRWRCGTRTRPWWPGTITPAEWRTGDVAQPGPQRPSWCYGTPGLARARQLAGL
                     ALSNPQRQHRAETVLARSVSDEAQLALLHDDSLCHGWAGFVHTTARMAAAGPDSELAAL
                     LPGLRARWEQRRLGVSDRNGMLEGTAGIALTRHTPDVGKLPTTRWDACLLLAPADTSNH
                     RTRKESDDQHDQH"
     misc_feature    complement(10391..10393)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11236..14283)
                     /locus_tag="BLS56_RS10215"
                     /old_locus_tag="SAMN05216174_10465"
     CDS             complement(11236..14283)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="BLS56_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10465"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_091449756.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-191,
                     bitscore: 632.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.9e-13,
                     bitscore: 44.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-27, bitscore:
                     90.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRATDKKPLYRHTGVALLRAAAAPLTNAPDHWPDLTDPRSCRTWL
                     DTVWSSPRLADAVRQASPSLGAAVDTIRSGHLVEDKQIRSATLSTARYLLRSIGRPTPF
                     GLFAGVAPVELGAGAQARWGEEHRAVARVNTEWLADIITRAEGCPELLRRLRVVVTDLA
                     VRRGGRFEVPQGPNRVTVRHTPAIAAVQDKAAVPVRFGVLIDTLAVDFAADRSKVQAML
                     TELVRSGYLLTNLRAPFTVTDPFTHLMDQLHETEADTLPDTAAFVRDLNAIHVELHHHN
                     HATTTRDDQRRARATITASMRQLSPVGRTPLAVDLMLDCEIRLPHHVAHEMERAAGALL
                     RLTRQPTGEAAWRNYHSAFIDRYGAGTLVPLADVIDPDTGLGFPAGYQGSVLPASSSNV
                     SERDERLLALAWQALATGTREIILTDDQIGELTGTTFDEHFIPPHVELSARVHATSAAA
                     LDAGDFLLTVAPARSAGTLTSRFTPMATGTGLADAYRALPAATVGALRAQMSFGPLYPH
                     AENVCRVPAYLDHLLPLGEHRAPGGDHALITVDDLAITATRDRLHLVSRSRRRVVEPQV
                     FHALALNKQPPLIARFLAHLPRAFSAAWYQFDWGPHLRLPFLPQVRYRRTILSPAQWRL
                     TTADLPASPDHWRPVLDRWRQRWSCPDVVELRDADRTLRLTLNEPTHASLLRTHLTRHG
                     QAILHTATPADDFGWIGGHAHEIALPLVTTRPAAPDPLRGQLPEVTNTHGHLPGAPDAT
                     WLSAKVFTHPERITEIVTEYLPDLLTMLGTTSCWWLRYRDRHETDHLRLRVQTSPDRYA
                     ACTKAVGEWTRRMRQKGLVGRLVYDTYRPEIGRYGSGPAMDAAEDVFAADSATVAAVLR
                     HRPGTDRDLIPFVVANMVGIVDGLFGDRGEAMNWLGTRPVPSTPAIDRAVTDQAIRLAI
                     DSAALAQVSGWDSEIGQAWQDRTDALVAYREHLPPEFDIDVVVESLLHMHHNRVVGIAP
                     DTERICRRLSRQAALAWRARQEGSGQ"
     aSDomain        complement(13570..13815)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLS56_RS10215_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.50E-14"
                     /identifier="RREFam001.1"
                     /label="BLS56_RS10215"
                     /locus_tag="BLS56_RS10215"
                     /protein_end="238"
                     /protein_start="156"
                     /score="44.3"
                     /tool="antismash"
                     /translation="VVVTDLAVRRGGRFEVPQGPNRVTVRHTPAIAAVQDKAAVPVRFG
                     VLIDTLAVDFAADRSKVQAMLTELVRSGYLLTNLRAP"
     gene            complement(14356..14526)
                     /locus_tag="BLS56_RS10220"
                     /old_locus_tag="SAMN05216174_10466"
     CDS             complement(14356..14526)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="BLS56_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10466"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_091449757.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.3e-12, bitscore:
                     40.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATISADAPPVEDPFALDVRIITDVPPGHPLSACGNGTDDGCDP
                     TCASACISDGV"
     misc_feature    complement(14554..14574)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     gene            complement(14653..14952)
                     /locus_tag="BLS56_RS10225"
                     /old_locus_tag="SAMN05216174_10467"
     CDS             complement(14653..14952)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10467"
                     /product="hypothetical protein"
                     /protein_id="WP_091449758.1"
                     /transl_table=11
                     /translation="MNAGGLRGIRAVIVAADSTVGLVAQSIDDLAAHLPPQHAPRMCPL
                     CSTERWPCVRFRDAAHHVRAAGIDIGELVPRDLHRHLQPPQPSPQAHQTALPPP"
     gene            complement(14949..15281)
                     /locus_tag="BLS56_RS10230"
                     /old_locus_tag="SAMN05216174_10468"
     CDS             complement(14949..15281)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10468"
                     /product="hypothetical protein"
                     /protein_id="WP_091449759.1"
                     /transl_table=11
                     /translation="MSTAISDKAIPVPSGRNTTPPRASVVVGAFAATPVGHPVLTAAAR
                     LATQHRLRAQSHRLVCDPHADDHVVAAAARSVDAARAVLIDWIDVWSGRRRLPRYQTPT
                     GPAVTA"
     misc_feature    complement(15328..15341)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.68"
                     /tool="antismash"
     gene            15540..17081
                     /locus_tag="BLS56_RS10235"
                     /old_locus_tag="SAMN05216174_10469"
     CDS             15540..17081
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10469"
                     /product="hypothetical protein"
                     /protein_id="WP_139190595.1"
                     /transl_table=11
                     /translation="MPRKAGASGKAERDQLRDRMRALGCSVAQIAAEMSRRFNLRPRAA
                     WRHALGWPQWKLAQEYNTAHPGAKLADNRISEYESWPHGGTAPSVRYLSNLAATFGHGC
                     TPAHLVDVDDMEHLSPTDRRLLAPAGDALMVSSANIAPFPETHPDLRLASRNINTVGSR
                     GNRRVVRRDARGLPIREEVVMAAEESAQFRRWSATTNVDDEVLEQMAADIAEVASSYLT
                     DPPATVFSRLIGARDDVFALIAGRQHPRHSMELYKIGGQMCALLAHASADLGHPHAANT
                     HARTALHCAEVASYTPLRVYTRWVQSNVAYWDGRYDDAAGLVEAALPDATSGTALLRLT
                     SQQARINAARQDSAGVVRALAAASAAPTDPTADEPGVFAFATGKAAYYASEAHRELGGD
                     KHLDAAIDWALTAVNEFAAERHPNAQFVAAARIDLTRAHLARGDLDAVGEHLAPVLSTV
                     AEQRTVPVISRVRSLTTLLSGHPGIESSTVASLRDDLAEFCSTPAASPSELNSAD"
     gene            17108..17587
                     /locus_tag="BLS56_RS10240"
                     /old_locus_tag="SAMN05216174_10470"
     CDS             17108..17587
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019047352.1"
                     /locus_tag="BLS56_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10470"
                     /product="LOG family protein"
                     /protein_id="WP_091450039.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 4.6e-09,
                     bitscore: 31.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVQVAVCGPRHCTEQDQADAQQVGKLLAQAGATVICGGGTGVMA
                     AVAAGARAENGLVIGIRPNDSTEGANPDLSAVIVTNMGEARNAAIVWSADAVIAIGGSW
                     GTLSEIALAKRRGGIPVITLNGWTVLDHDGNPLPDTTLTADSPQDAVDLALNGSR"
     gene            complement(17584..17823)
                     /locus_tag="BLS56_RS10245"
                     /old_locus_tag="SAMN05216174_10471"
     CDS             complement(17584..17823)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010307627.1"
                     /locus_tag="BLS56_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10471"
                     /product="AlpA family transcriptional regulator"
                     /protein_id="WP_091449761.1"
                     /transl_table=11
                     /translation="MSDEVNKLSRTPTLSEIRETWPAAVGVPEAAAAFGLSRSHAYELI
                     ARGEFPARVLRVGSRYRVVTASIITTLSDDRDVL"
     misc_feature    complement(17857..17877)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    17868..17878
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            17897..18475
                     /locus_tag="BLS56_RS10250"
                     /old_locus_tag="SAMN05216174_10472"
     CDS             17897..18475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152105.1"
                     /locus_tag="BLS56_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10472"
                     /product="hypothetical protein"
                     /protein_id="WP_228771532.1"
                     /transl_table=11
                     /translation="MARQPKDFRIAWASAEPSAPLGYLLTGPETAIPMRFRASITLETP
                     PATVTIEVFVGADLRPRVHELAIRSNTQFQITTTVLRQVLVEQLLREAVAKAEVPVSAL
                     PPGAILGAPPQPEVAHGKAETDAQTAARVYSQAVTSGSPAPAMAVAREMGRSRAQVARY
                     LRKARQMGLLPELAPPGVENDREEGQTHQ"
     gene            18472..19683
                     /locus_tag="BLS56_RS10255"
                     /old_locus_tag="SAMN05216174_10473"
     CDS             18472..19683
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452814.1"
                     /locus_tag="BLS56_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10473"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_091449762.1"
                     /transl_table=11
                     /translation="MSDPIKKITLKSGAVRYRFVIDVGRDPETSRRLQKTFTFDTKREA
                     RAEYDKIRHQTNEGSYIRPAKVTVAEYLTGWLEGATRDLRDSSKRSYRDALRPAFERLG
                     PTAMQKVTKADIERMVTWMATEGRRRGGKPGTGLGPRSIQLTLGRLTAAFEMATLEGLI
                     PRNVAKLVKPPKYEPAEPETWSKAEVHRFLTKAKKDRLHAAWRLSLYGLRRGEVLGLRW
                     KDVDFGPFSAVCGKHSERWCAECYGAKHATVHVRQSRVLVEGKILIEPPKSRNGFRKLP
                     LDARLAVALRALKVAQAAEKLAAGEGYVDSGYVVVNELGQPVHPEWYSDEFQRLSKRAG
                     VKRIVLHEGRHTTLSLMEKAGVPISIISKWAGHYDTAFTYSTYVHADDEDLKTGTDALG
                     RIYK"
     gene            complement(20493..20861)
                     /gene="cutA"
                     /locus_tag="BLS56_RS33005"
     CDS             complement(20493..20861)
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cutA"
                     /inference="COORDINATES: protein motif:HMM:NF015077.5"
                     /locus_tag="BLS56_RS33005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="WP_407640506.1"
                     /transl_table=11
                     /translation="MVRAASSPNSKGMRTVSDVVEVVITAPDADWLAEFARMLLDERLC
                     AGGHSIERVRSLYRWQGDIHDKAEARIALHTRSVHVDAIISLANARHPYDVPCVVAWPI
                     ELGNPDYLAWVMAETRSS"
     gene            complement(20809..21420)
                     /locus_tag="BLS56_RS10265"
                     /old_locus_tag="SAMN05216174_10474"
     CDS             complement(20809..21420)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155533.1"
                     /locus_tag="BLS56_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10474"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_228771533.1"
                     /transl_table=11
                     /translation="MSEMAEVMKERRADLGMSQAELAAAVGVQTRQIRRYEAGEQHPVL
                     PVAVAIADALKITVNELAGMTSQRLSLSGEWWASWQTWKDGVEVITAQEVRIGQQGDLL
                     SVRTTTRGIEVEDGGYHWQGELRLWDNEILMGWYAAADGSVRSKGTFYFVLHPHGLTMR
                     GRWVGLSYDGKIITGWGGVAKSEDGARGIISELEGNADSV"
     misc_feature    complement(21493..21509)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.36"
                     /tool="antismash"
     gene            21620..21844
                     /locus_tag="BLS56_RS10270"
                     /old_locus_tag="SAMN05216174_10475"
     CDS             21620..21844
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010308006.1"
                     /locus_tag="BLS56_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10475"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_228771565.1"
                     /transl_table=11
                     /translation="MLDVSVNTIYRAVETGELNALKIGKALRIPGAALNAYLSQCAEPV
                     DAQVLSDQVASVADAGTAQDAAITSEVSR"
     gene            21841..22236
                     /locus_tag="BLS56_RS10275"
                     /old_locus_tag="SAMN05216174_10476"
     CDS             21841..22236
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10476"
                     /product="hypothetical protein"
                     /protein_id="WP_091449765.1"
                     /transl_table=11
                     /translation="MTTTTTTNVEQEDASVGARLLRELRVGEVALAIHHSGAKLHRELS
                     DDEITVLVGQGAAWVGVERLRLDAEYAREVTRRGDLTRHRRLWGSRARYQLCVDLAWQV
                     SADRASYRAAAAAFRASRKGAGRGHAA"
     gene            22233..22520
                     /locus_tag="BLS56_RS10280"
                     /old_locus_tag="SAMN05216174_10477"
     CDS             22233..22520
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_10477"
                     /product="hypothetical protein"
                     /protein_id="WP_091449766.1"
                     /transl_table=11
                     /translation="MSDQYPTLTPVVDAVVTALYLSPFEPDQVPALGADRVARYVARMA
                     LLPEFDALIGVLRKHGHPGSRYVDHARLVACHRAARLVRRSSRRRGHRQR"
     gene            22617..24059
                     /locus_tag="BLS56_RS10285"
                     /old_locus_tag="SAMN05216174_10478"
     CDS             22617..24059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156733.1"
                     /locus_tag="BLS56_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_10478"
                     /product="DUF3987 domain-containing protein"
                     /protein_id="WP_228771566.1"
                     /transl_table=11
                     /translation="MPVPPSHDPADPWLYPVTAPGADPWTEPVGDLAPVYALPSVLTST
                     GTGTGTGTGAGALDDAAMGERVARIRGWLPPVDPAVFGCFLGQLATHLDPFTEADPVGV
                     LVTLLAAAGVHMGPGPHVVVGGFERHPLLTWPIVVGPTGTGRKGTGYNVAKALLSHAIP
                     EFVADNVHSGLSSGEGLASVFATDDTPGKGKPRLLPEHDVRLLAYEPEWASVMARMKRE
                     GNTLSATLRAAWEGGNLSTLNVDARTARQSHVGIVAHITPTEFRDRVSSTDMAGGTYNR
                     FLPIAVAQSKFLPAPDPIDPTTLLQFGAALSDRLAAASRLDALTLDPDAAQLWRRLYVD
                     FSAAADGDGDGVLAQFTSRAVPNCLRIAATYAALDRTDHITTTHLTAAAALVRYSIDSA
                     RVVLRPNDDLVKLLTHIREHGPQGCTREQARDAFQRNKSAADVGRLLDHLVTAGQVTAT
                     SRPPAGGRGRPATVFTATTPRG"
ORIGIN
        1 gcctgcgtga ggtgtagtgg atcggcgtag acggcgaccg cttcgtgcag gacacggtcg
       61 gcgcgaggcg ctccagcggg acgtcctgca tggccaggtg ctagctgagg taacagtcgc
      121 tgaccggctc ggtcccggcc gccgcaccag tgcacattgg ttcagcatcc acaactgtgg
      181 tggcgatgca atgctgcacc accgcaccct caaccccgtc gtcattcgcg actggtcacc
      241 gaagatggag acgttcgcgc tggccagcgc ttggccagtt gaacaaggtg ggtctgctta
      301 acccgaacta gtcaccaact acccaggtga ggtgccaagt ctcctggcca aggtgtccgc
      361 gctggccgag gaacacggtc tactgccgct cagcagccct tgcccatgag ctccagtgac
      421 ggctaccgag actgcagatt cttcgcagtg tcggttgttc aagccggtta cgggttaggt
      481 gtcgtatgcc gctcgtacag ccgcgcctcg gcttcagagt gtctgaagcc gaggcgcggc
      541 tgttctcagc gatgtagcgg atcaccgcgg cgctcgggtt acagcgtggc gggcgccttc
      601 ttgtaccagc ttgtgatcac accgaccagg tggacgatgt tctgcgtgcg catgatcggt
      661 gcgaaggcat caggctcgaa gtccttgtgg gcgtcggtgg tgcgccagat gctggactcc
      721 gtgacggggg cagccatgtg agggtcgagc ttcttgaaga acgcggcgat gtcgtcgagt
      781 tcggcggggt tgtcgcccgc gcgcagttcc cggaacacac cacccagcac gcgcagcatg
      841 cccaccgagc cgagcagcga ggtgcgcctc agcttctgcg acatggtcag ttcatcaggc
      901 ttgcactcgg cctccgggtc gtcctccgtt actgcggcca ggtcgccgaa ggcggtggag
      961 atgatgtcga ggaagtcctt gacctgctcg atgacctcac cgtccgtcag gctctgttcg
     1021 gccttcttgc tgatcctgcc gccagctccg gcgatgacgg cgcgggtgat gtccgcgacg
     1081 tgcttggcgc ccatcaggtt ggggttcttc agggtcatgc ggtcctgctc cgcgtcgacc
     1141 cgccccttga gcagcgggtg gtcgatgacg tcggacaggg tacggttggc gaccttgtag
     1201 ttgtcgaagc gcgcgcgcac ggcactgctg atgcccttgg cgttgtcggc gacatcgacg
     1261 aacatctgct gcgacttgat tgggtcgggc tcgacgtaga tgtccagacc gacgtactcc
     1321 tccttgagcc gagtcatctg ccctacgagc cgctcgcgct cggcttggag cttcgcggcc
     1381 ttgtcgacgc tgaccttgcg ggccagttcg cggtcgatcg cggagacggc atccgtgatg
     1441 cgctgcttct cgatagagac tcccagaatc cggtgctggc catcgatggt gcgcagcgtg
     1501 gcgatgccgc cgatcgccca cggaacggtc agatagccga cccgtccctc ctcgtcggcc
     1561 ttctggaacg tgcagccgcc gccgtcacgg gcaaggagcg ccggtgcgac ccagtcctgc
     1621 ttggaatcga ggtactcacc gaactgcttg gcgtgcagcc ggtcgacctt gcggttgtcc
     1681 ttgtcgacgt tgttcgggtc ggggaccggg aggatcgtcg ggagatccag gagaggaacg
     1741 cgcgtcgagt acaccgcgcg tcctccctgc atcgtcttga gagccaagta cgtgctggag
     1801 tcctgcggcc tcgacagcag tcgggggtct acgttgatgc tcatggctaa cctcctactc
     1861 aggggctcag ccccctaatg gagggtgagt ggaacttacc gtatcggata cctatctaag
     1921 cctcaagatt aaatcttatt taacccagca agggctagta tgtgtagtcg aagttgactg
     1981 accagcaggc gctgctcgac agagccgacc ggagatggga gtcaagcgtc agaactcgac
     2041 tccacagcag aacgaacccg ccaagtagcg accgacgctt caacccgggc gggctcaccc
     2101 ccgctcacgc gccgccacca ctgcccctcg acgtcgcgga acgcgaacgt gatgtctgcg
     2161 gtcccccagt tcagcatctc caggctgacg ccatcgatac ccagcccggg cagctcgacg
     2221 tcttcacgag gcccgagaac atcagcagcc ttgagcggac ccggccgggg cgtggcgttc
     2281 cacaccaccg tgctcctcaa ggctcaatct gcgtggcgga cgccctcatc gtcggtgaaa
     2341 accatgtcca agacgacgac ttctagcacc ggcaccgacc cgtggttgct gatgctcacg
     2401 cctgggaaca tcgaatttga gtttgggcgc ctcatcggct tgaactcgat cacgaccgtc
     2461 gaggcctcgg cgagttgtct cgcccttcga gccgcatccg ctgcgtccac ctgctggacc
     2521 tgctccgctc ggagtttcgt catcaccttg ttgtgcaacc gccggtcccg aatcagcacg
     2581 acgacagcga ccgccacggg acgtggtgat caagtaagtg accaactccg ccacgaggcc
     2641 gccgagtggt cgcgcaccta ccgaggtcca gaggaacgac aaggccctcc cccggatctg
     2701 ttccgggaaa gggccttgat cgtgatattc gctggtcagc ggcgtggtcg gagcagtctc
     2761 agtacggtca gggtcattcc ggcaaacagg aggaccatgg ccgtggcagg gtatgcctcg
     2821 acaccatcga ccaggagcag ggcgatgaag gcgaacagga tcatactcag agcgctgagc
     2881 agggcgaccg cgttcagcac ccacctgtag ttgtccaaca ggtcacgcag aaatggcctg
     2941 cgacggcgct caccggatcg ttggttggtt ccctcctgtg atgcgccctc gtcctgtgtg
     3001 gcgttatcgg tttgggcgcc ggagtgactg tatcggtggt tggtgatgtt gtggtgggtg
     3061 ttgtaggcga tgttgatgtc gccgtgcacg gcgacgctgc ccatgccacc ggtcagccgc
     3121 tgcagcaccg gctcgtcacg gtgctgctcg ttcgggcggt ggtcgacgag ttcggcgtcg
     3181 agcacgagtt ccttgggagc gatgatttca agcgcggtag acatctcgcg caggttcgcc
     3241 cagagcatca tgacctgctc gacttgctcg ggtctgagcc tgcagccgcg ggcgaaggcc
     3301 cgaacttggt gggcgtgttt gggcaacgtg gtgttcttct cggacacgaa gcggtaggcg
     3361 gtgctacggg gcagcttggc gtacatggcg acctgcccgg cagtgagccc ggagtgggcg
     3421 agcatggctc gcatcagcgc catgaagccc gtctcgtccg ccgccgtgat cgtcaggtcg
     3481 ccgtcgggct cggaggcgac agcaggagag gtgctcatcg tggcccctgt ccgtcgtccg
     3541 cgaacgccgt cagtgcccgc acgagcctgc ggccgaggct gttgcccgac ttggtgggca
     3601 ctaccaaggg cacgatcacg gcgagcagac cgatggggac cagcacggcc gtgtgaacct
     3661 ccaggcctgt tcccagcagc aggtaaacga acacgaagga ggacatcacc agcgtcagca
     3721 ccagtagcac cgtttgccag gtccacgcgg ggccagccgc cacgtcggtg acacccggcg
     3781 cgggcttggt cgtcgctgtg atgtcctcgg actcgcggcc cgggatgtac tggggaccgt
     3841 cgtggtcccc gggtcttgtc gtcacgggtt cctcatcctg gccactggag ggtggccgcg
     3901 cgggcggggt cccggtgggc agaaccgtct gctcgagtcc gtaggcggag gcgccgtcgg
     3961 tgctcgacgc catgtcgagc actgacgagc ccacgcacac aggtaagaac tcgagcggct
     4021 ccgcttggag gggacaccgc gctgggggat gcagtcgagg cttgttgcct ggtctcgaag
     4081 ccgtgatcga tttggccctc gatcacggcc gccccggaca tcgggaccgg ggaccgcaaa
     4141 gttgatgatc ctcaggcgat acgcggaaac caagccgatg cgccctgcac cgaaaaactt
     4201 gtgtccagcg tcggctcgcc cttccacacc cgtggcaccg agacagtgtc caacagcggg
     4261 ttcgtgtctc ttcgacggct cagcgggtgt ccaacgcagt gtccaacggt tgccgtgatg
     4321 tacagcaaca tcgtccgctg aactcgccgc gaccactgcg ccggggatgt tatggctgat
     4381 caacgcccca tcagaagctg ttggacagcg ccagtcccct atcgttgctc ctgcaggttc
     4441 aggattgtcc gacgatcctg ctgcccccgg acgcccgcta gtgggatgca gtcgagcact
     4501 ggggaggtgg gacggtccgt tggcccggat ccccgccatc acacgaaagg ccccggaggt
     4561 tctgcgaatc tccggggcct gacgcgtttt cgttccaccg gaccgtggtg acagcagggg
     4621 cacggtgccc tacaaccaat cgccagccga gagctcgccg cgcagccggg tgagggcgcg
     4681 gtgctgggcg acgcggacgg cggtggcggt caggccgatc gcggtggcgg tctcctgcgc
     4741 ggagaggccg acgaccaggc gcagcaccag gatctcgcgc tggcgcgggg cgagggtgtc
     4801 caggagcctg accagccggg agcgcatctc gccgcgcagg gtgatctgct cggggcccag
     4861 gttgtggtcg atggtgtccg gcacgtcggc gaccggctcg gagcggtcgc ggccggagcg
     4921 gcggtagtag tcggcgacct tgtgcgaggc gatgccgtag acgaacggca agaaggactc
     4981 gcggtcgtcg gagtagcggg gcagcgcgcc gaggacggcg agcaggattt cctgggccac
     5041 gtcgtcggcg ttggagaacg ccgagccggt gcggccgatc cgggcccggc agtagcggat
     5101 gatcgccggg ttgatccagg cgaacagggt gccgatggcc tcctggtcac ctttgagcga
     5161 ggcgtccacg agttcgtgga aggcggcgct cttcaaccgg gcgaagaccg cgtccacgct
     5221 ctggggccga cggggacgcg acgccgacgg cgttgcggag gacgccgcct gccccgccag
     5281 agccggagcc agggtggtga cagcctccgg acgcgggacg tacttgacca ccgcagcgac
     5341 cccgcgtggt tccttccgca gcgccgacaa ggccgagagc cgcgcgaccg cggcggcctc
     5401 cacaccccgc agagtgcctt caacgtcgag ttgggcggtg gtcgaggcga caagtccccg
     5461 ccccgcgtcc cccatccagg ctccgatgtc gatctcagcg tcgttgacca cgggtgggca
     5521 cctcctcgat ctgcagcaac gtcaggaact cgtcgaactc accttgcacc tcggcacgca
     5581 gctcgcgtac gaagccgctc agctggatct tggcgtggcg ccgatgggag cggatggtgc
     5641 tttccttgct cgcgaggatg tcggcgatct cgtaggtctc gaacccctgg tagtagagcg
     5701 cgatcacctg cctgcgcacc ggcgacaacc tcatcagcag gtcgagaacg acctcgtcga
     5761 gctgccccga gccgatctcg ctcaccttcg gacggtcgcg ccgcgccgcg agggccgcct
     5821 tctgcctccc cagcacggcc cgctgcgcgt tgcgggaagc gtcccggatg gcgatcttca
     5881 ccacccaggc cagcggactc gtaatctcgg cggtgctggt gagcaacgcg atcatcgcct
     5941 ccgaggccga atcagcggac tcctccaaac cgaagcccat ctggcgcagg acggcgaccg
     6001 tcttggggaa cgcgtgacga aagaagtcct ggaactccgc gtccatccgc ccaccacccc
     6061 ttcatcgctc cgccaccgtg ttcaaggtgt agtgccacga gcccgaccgc gcgtgcaacg
     6121 cacaccagaa aatgacgatc acagcagctc ctggccggag gcgcactggc ccggccaggc
     6181 aagtggcgat tactcactcc cgaaaccaca gtcgttcacg gcgcagctca ggcgaagtgg
     6241 gtgtaggcgg cgaagctgtc caggtcgtgc cgcgagtggt cgtagcggcg agtggtgcga
     6301 gctcgcggtg gcgggcgtag tcccgggcat cgcgcatccc gatcccggcg cccagggccg
     6361 cggtgatggc gatgtggcgc acaggctgtg tgggacaact gctcccagga ggccgatacc
     6421 cgccgccttg ccaacctccg gaccagctct cataggttgc accaagtcag gcacccaccg
     6481 ttgcggatgg ccactccacc cgggccagca ggaccaacga taacagcgaa agtcacacgc
     6541 catgtacaac gaaaataacg gcacagggtt accaacgctg cctgtagtgt gtgataatcg
     6601 ttgcgtgaac ctggtggatg caatggaagc gatggtcaac cacaccaccg aacagtgggg
     6661 tctgatcacc gcagcccagg ctaagacggt gggtgtggac ggcatgacgc tgcagcgcgc
     6721 cgtcgaggcg ggcctgctcg agagagttcg ccgcggctgt tacctcgcta cagcagccac
     6781 catgcctaaa cacctccagc ccaaggccgt gtggctggca ctgaacccga ccgtcccggc
     6841 ctgggagcgt ccagatctcg accccgacgg cggggtgatc tcacacagct cggctgctct
     6901 aattcacggt atcggcgacc ttcgcgcgga catcgtcgag atcaccgttc cgcgacgacg
     6961 ggtgacgcgt gagcaggacg taagtccgcg gcgcgcggag ctgaccgagg atgatgtcga
     7021 actcgtcgac gggctacctg tgacgacggt gccgcgcacc atcaccgacc acctggcaga
     7081 ccacatcgac ggcggtcacg tcggcgcgat gatctaccac gccgctcgcc gcggcttggt
     7141 cgacctcgac cagttggcaa ataggtcagg aacgtacgcg cgtcgatacg gcctgccccg
     7201 aggtcacggc cgcagcctga tcgagtacct gctcgctcag gctggacaca gcctcgccga
     7261 tctcgtcgcc cccaacggac tcgtacgcac ttcagaccta cgtcacatct tggaggtgct
     7321 gcctaggacg actctgtctc tgtcgggcac gccgatcaac gctgcgctcg cgcagatggt
     7381 ggaatccatt caaggaatgg ttccggctgc gggggtcctc gagaacctgt ccgtgccttt
     7441 gacttcgttc gcacgatccc taccgcagct gtcttcttcg cacatcgagg gtcttcgtag
     7501 gtctctgtca cagcttgacg tgctcaaccg gcaggctgag ctacttcgag cgctcgagtt
     7561 gccgcatgcc tcggcggaga tcgcgcgatc ttcaagcatt atggctgcag cgctcgcggc
     7621 cgcgggtgcc gaggccgcgc gatctgcagc gatgcctggc gaagacgacg aggatatgcc
     7681 ctgatggact tacccgccgc agcgcggcga cgactcaata acctggccag aaaccacgcc
     7741 cgcgccaccg gtcagaacag cacgaccttg gtagagcgtt acctctacga ccgactgttg
     7801 gcccgtctag ccactcacga cgctgaaggt tggctggtca agggcggcca agccctgctc
     7861 cgccgctatc cgcatgcccg ccacacccga gacctcgatc tgctccacct gacgtcgttg
     7921 agcgccgatc ttgacgacgc ggtcgcggtc cttcgtacgg ccgtcgctct cgacctcggc
     7981 gaccacctcc actacgtcta tcgcgacacc acaaccgcat cgaaaggagg acaagcccgc
     8041 cgcgtccgat tcaccccgta ctacgggcgt acagcgctca acacgatcag cgtcgacctc
     8101 gtcgtcggcc atacgccgtt aggtcagccc accacccgtt ctctgcagtc atgcgtaccc
     8161 ggcttggacg acggccaatg gccggatgtc cacctgtacc ccatcgtcga ccacatcgca
     8221 gacaagatct ccgccatgta tgagcgccac gggcctcagg ccatcccgtc ctcgcgctcc
     8281 catgacctgg tcgacctgct gctgattatc ttgagcgaga ccatcgacgg caccacaatg
     8341 cacaccgccc tgcacgccga ggtcgctcgc cgccgccaac gcggcaccat gttgatcctg
     8401 cccgccaagt tccatgttcc cggcggtcag agctggagtg cgggctacgc tcgcgatgcc
     8461 cgcggcgtga ccggactggc gcgccaccaa accctcaacg aggctgcggg ccttgccgcc
     8521 gcattcatta cccccctgct gactgcgact ccacctggac gttggacgcc ggatcatctg
     8581 cgctggctta acccgccata aaccgcatgc gcctacagcc cactgcggtc gcggggcacg
     8641 ctacgaccgg aaactcgccc ggccaggtcg agatcagcac cgcaatcgct agccccggcc
     8701 gccgtccacc ccttgacctt ctagctcatc ggactgtctt cccgacctca actcgacgcc
     8761 tgtccggtag cgcccctgcg gatcgcgccg cgaaagcgtc tgcggggagc ccggtcaggg
     8821 tgtgacaacc atccggacgt ggcgcttgtc gatgactact ccgccgacgg ggaggttctc
     8881 ggcgggggtg tcggccgggt aggcggtgat ggtgggctgg gcggtgcggt cgctgtccca
     8941 gtggcggatg tgttcgcaca ggcgctcggc taggtgggct ccggctgggc cgtggccggt
     9001 ggcgccgagt tcgtagcggc gttcgccgtc ctggtctagg gggcggggct tggtgaggta
     9061 ggcgagggag tcgccctcga ccatggcggg agtgcggtgg gcgaacacgg ggcggcaaag
     9121 accagcgtcg atggcggcgg gttcggccgc gaggcggcag gcgccgggtt cggtggcggt
     9181 cagccagagc caaatgtggt cgaacgactc gttggcgacc actgaggcgc cggaccacac
     9241 cgtggtggcg ggctgggtga agacctcgtg caacgcggcc gggtcgatgt tctggtcgga
     9301 gtcccagtac agggcgacgt cgtcgacgat gtggccggtc tgttccccgg acgggacgat
     9361 gccgatcatg gggatgaatc cgcagagcct gctgtcggtg gcccgtagcc cgcggtcagt
     9421 gcgggtgaac gcgacgctgc gggcttggcc gcgccagtgc aggggcacga cgagcgtccc
     9481 tccgggggca agctggtcga accaggcggg tggcaggtcc catgggccga cggtgacgat
     9541 gatcttgtcg taaggagcgt ggtcagggtc gccgagtgcg ccgtcgccgg tcacgacgcg
     9601 gacctggtcg tggccggttt tgtcgagggc ttggcgggcg tgggcggtga cgtcggggtg
     9661 gatgtcgatg gtcgtcacgc tgccggtagg gccgacgagt tcagccagga gtgcggcgtt
     9721 gtagccggtt cccgcgccga tttcgaggac gtgatcgccc ggctgcgggt cgagctggtc
     9781 gagcatcatc gccacgacgg tcggaacgga gatgcaactg gcggggcggt cgggacctgg
     9841 cttgatggtg atggccttgt tcgcgtaggc gtcctcgacg gaagcggcgg gcacgaacaa
     9901 gtgccgaggg acggttcgca gagccagctc gatgcggtgg gagcgcaggt gcccgctgtc
     9961 cttgaggtgc tcgaccatgt ggtcgcgcag gtcctcgggc tcagtgctgg tcatgctggt
    10021 catccgattc ctttcgggtg cggtgattcg aggtgtctgc tggtgcgagg agcaggcagg
    10081 cgtcccaccg ggtggtgggt agcttgccca cgtcaggggt gtgccgggtc agcgcgatgc
    10141 ccgcggtgcc ctccaacatc ccattccggt ccgacactcc gagacggcgc tgttcccagc
    10201 gggcgcggag gccaggcagg agagcggcaa gttcgctgtc gggaccggcg gcggccatcc
    10261 gcgcggtcgt gtggacgaat cctgcccagc cgtggcagag ggagtcgtcg tggagcaggg
    10321 cgagctgggc ttcatcgctg acagaacgtg ccaacacagt ctctgcgcga tgctgccgct
    10381 gcggattgct taaggcgagg cctgccagtt gccgggctcg cgccaggcct ggagtgccgt
    10441 agcaccagga cggccgttgt ggaccgggtt gagcgacgtc accggttctc cattcggccg
    10501 gggtgatcgt gccaggccac cacgggcgcg tccgggtgcc gcagcgccag cgacccaagg
    10561 cggcgtcgaa gtggtcgatg gcctcggcgt ggtcggagac ggtgacgccg tggatcaccg
    10621 cagtggccag tagcgccagc ggaccggcga tgccgtgcgc gaggcccagg ttcgcgtggc
    10681 cgcctggcca ccgcgggtcg ggccggtcgg cgggagcgtt tccagtccac cagcccggca
    10741 acgtctggcc gtcgacgcgc agcggctcgg tcaggcgcac caggtaggcc agcacgtcac
    10801 gcaggagttc ggtgttgtcg gtctggagca ggtatgcgcc gatcccggtc agcccgttga
    10861 tcaggtcgaa ctcgcgcaac tccggaagca gacctcgctc gatccggtcg tgcgcctggt
    10921 ccaagcggtg ccgggtgagc ttcgcaatgt ggtcgtcaat cgcggccagc gccgcggcgt
    10981 aagagggttg gccagcagtg cgcagaacga aggcgaccgc gggggctccg tggaacaggc
    11041 aggcgtccgg atgggcggca acggggtcgc gggtcatggc ggtgacccag cggtgggcgg
    11101 tggcccagtc gccgacgccg gtctgggcgt aggtgatgtg gagcagggcg agcccggcgg
    11161 ccccatcgga cagggactgg tgccagccgg gtttgggctc gtgctcgggc ggagggctgc
    11221 acgggtcggt gtgagtcact ggccgctgcc ttcctgccga gcgcgccagg cgagggcggc
    11281 ttgtctactc aggcggcggc agatgcgttc ggtgtcgggg gcgatgccta cgacgcggtt
    11341 gtggtgcatg tgcagcagcg actccaccac gacgtcgatg tcgaactcgg gcgggagatg
    11401 ttcacggtat gcgaccaggg cgtcggtgcg gtcctgccag gcctggccga tctcgctgtc
    11461 ccagccggac acctgtgcca gtgctgctga atcaatggcc agccggatgg cctggtcagt
    11521 cactgcccgg tcgatggcgg gcgtgctcgg gacgggccgg gtgcccagcc agttcattgc
    11581 ctcgccgcgg tcgccaaaca ggccgtcaac gatgcccacc atgtttgcca cgacgaaggg
    11641 aatgagatcc cggtccgtac cggggcggtg cctcagcacg gccgccacgg tggccgagtc
    11701 ggcggcgaag acgtcctctg cggcatccat cgccgggccg gacccatagc ggccgatctc
    11761 cgggcggtag gtgtcgtaga ccagccgccc aaccagcccc ttctgccgca ttcgccttgt
    11821 ccactccccc accgcttttg tgcacgcagc gtagcggtcc gggctagttt ggacacggag
    11881 gcgaaggtgg tcggtctcgt gtcgatcgcg gtagcgaagc caccagcacg aggtggtgcc
    11941 cagcatggtc agcaggtcgg gcaggtactc ggtgacgatc tcggtgatcc gctcggggtg
    12001 ggtgaagacc ttcgccgaca gccaagtggc gtccggggcg cctggcaggt gcccgtgcgt
    12061 gttcgtcacc tcgggtagct gcccgcgcag cgggtcaggc gcggccgggc gggtggtgac
    12121 caggggcaag gcgatctcgt gggcgtggcc gccgatccag ccgaaatcgt ctgccggggt
    12181 ggcggtgtgg aggatggctt ggccatgtcg cgtgaggtgc gtgcgcagca gggaggcgtg
    12241 ggtgggctcg ttcaaggtga ggcgcagggt gcggtcggcg tcgcgaagtt cgaccacgtc
    12301 tgggcagctc cagcgctgcc tccagcggtc gagcaccggt cgccagtggt cgggactggc
    12361 gggaaggtca gcggtggtca gtcgccattg ggctggagac aggatggtgc ggcggtagcg
    12421 cacttgcggg aggaacggca gcctgaggtg cggcccccag tcgaactggt accaggcggc
    12481 ggagaacgcg cgcggaagat gcgccaggaa tcgcgcgatc agcggtggct gcttgttcag
    12541 cgcgagagcg tgaaacacct gcggttcgac cacccggcgg cgggagcggc tgaccaggtg
    12601 caggcggtcg cgcgtcgcgg tgatggccag gtcgtccact gtgattagcg cgtggtcgcc
    12661 tccgggtgcg cgatgttcgc ccagcgggag caggtggtcg agatacgccg ggacgcgaca
    12721 gacgttctcc gcgtgcgggt agagcggtcc gaaggacatc tgggcacgca acgccccgac
    12781 ggtcgcggcg ggcagcgccc ggtaggcgtc ggccaggccg gtgcccgtcg ccattggggt
    12841 gaagcggctg gtcagcgttc cagcggagcg ggctggggcg acggtgagca ggaagtcgcc
    12901 agcgtcgagg gcggcggcgc tggtggcgtg gacgcgggcg gaaagctcca cgtgcggcgg
    12961 gatgaagtgc tcatcgaaag ttgtgccggt cagctcaccg atctggtcgt cggtgaggat
    13021 gatctcgcgg gtgccggtgg ccaacgcctg ccaggccagc gccaacagcc gctcgtcgcg
    13081 ctcagagaca ttcgaggacg acgcgggcag cacgctgccc tggtatccgg ctgggaagcc
    13141 gagtccggtg tccgggtcta tgacgtcagc caagggaacc aacgttccgg cgccgtatcg
    13201 gtctatgaac gccgagtggt agttccgcca agccgcttcc ccggttggct gtctggtcag
    13261 gcgcagcaac gcgcccgcgg cacgttccat ctcgtgcgcg acgtggtggg gcagccggat
    13321 ttcacagtcc agcatcaggt ccacggccag cggggtgcgc ccgaccggag agagttgcct
    13381 catgctcgcg gtgatcgtgg cgcgtgcgcg gcgctgatcg tcccgggtgg tcgtggcgtg
    13441 gttgtgatgg tgcaactcga catggatcgc gttcaggtcg cgcacgaagg cggcggtgtc
    13501 gggaagcgtg tcggcttcgg tttcatggag ttggtccatg aggtgggtga acggatcggt
    13561 gacggtaaag ggggcgcgca ggttggtcag caggtagccg cttcgcacga gttcggtgag
    13621 catggcctgg accttggacc gatcggcggc gaaatccacg gccagcgtgt cgatcaggac
    13681 gccgaagcgg accgggacgg ccgccttgtc ctggacggcg gcaattgctg gggtgtggcg
    13741 gacagtcacg cggttcggcc cctgtgggac ttcgaaacgg ccaccgcgcc tgaccgcgag
    13801 gtcggtgacc acaacccgga gccgtcgcag cagctccgga catccctcgg cgcgggtgat
    13861 gatgtcggcc agccactcgg tgttgacgcg ggcgaccgcc cggtgttcct caccccagcg
    13921 cgcttgggcg cccgctccga gttcgaccgg agccacgccc gcgaacaacc cgaacggcgt
    13981 gggacggccg atgctgcgca acaggtagcg agcggtggac agggtggcgc tgcggatctg
    14041 cttgtcctcg acaaggtgac cggagcgaat ggtgtcgacg gccgcaccca gcgacgggct
    14101 ggcctggcga accgcgtcag cgagacgggg actggaccac acggtatcca gccaagtgcg
    14161 gcacgaccgg gggtcggtga ggtcgggcca gtggtcgggc gcgttggtca gcggcgcggc
    14221 ggcggctcgt agcaacgcga caccggtgtg ccggtagagc ggtttcttgt cggtggctcg
    14281 catcgcggtt cctcgggcag gcggagcagg ggccggaggc gttccggccc ctgctcacgg
    14341 ggtgaacgac ggttctcaga cgccgtcgct gatgcaggct gacgcgcagg tggggtcgca
    14401 gccgtcgtct gtgccgttgc cgcacgccga aagcgggtgg ccgggcggaa catcggtgat
    14461 gatccgcacg tcaagggcga aggggtcctc gactggtggg gcgtctgcgc tgatcgttgc
    14521 ggacattagg tgcctttcgt cgtatcgggc agatcctcat caacctgacc agaaacacct
    14581 tgcgagacaa ggattcgagc caggagcctg tcgtgccgtc ccatggccgt ccggctgaac
    14641 gggacagcaa aatcacggtg gcggaagagc cgtctggtgc gcttgcgggc tgggttgggg
    14701 tggttgcagg tgccgatgca agtcccgagg cacgagttca cctatgtcga tcccagcggc
    14761 gcgcacgtgg tgcgcggcgt cccggaaccg gacacacggc cagcgttccg tggagcacag
    14821 cgggcacatc ctgggcgcgt gctggggcgg caaatgcgcg gccaggtcgt cgatgctctg
    14881 ggcgaccagt ccgaccgtgc tgtccgcggc gacgatgacg gcccggatgc cgcgcagccc
    14941 gcccgcgttc acgcggtgac cgccgggccg gttggggtct ggtagcgcgg aagccgccta
    15001 cgaccggacc atacgtcgat ccagtcgatc agcacggcac gcgcggcgtc gaccgatcgg
    15061 gccgcggccg ccaccacgtg atcgtcggcg tgtgggtcgc agaccagtcg gtgggattgg
    15121 gcgcgcagcc ggtgctgggt ggccagtctt gcggcggcgg tgagcaccgg gtgcccgacc
    15181 ggggtggcgg cgaaggcgcc caccacaacc gacgcccgtg gcggtgtggt gttcctgccc
    15241 gatggaaccg gaatggcctt gtcgctgatc gcggtgctca cgttgccgac ctccttgatc
    15301 cgtacgtggc ggggagtgct gtcgtcggta ctcagcgtgg cctacccgaa gggtggttca
    15361 cctcctgctc gggcgggaac atttcctcgc ttactccagc cgtcctgatc agcgcgaaca
    15421 cggaatagac gggtgaaaag ttccgcccct cggagctggc gcgctcccgg cggcccactt
    15481 ctcggcgcta ccgttcgcag tagctgcggc acacaacggg tgcaccggga gggtggtcga
    15541 tgcctaggaa ggccggggcc tccggaaagg ctgagcgcga tcagctccgc gaccggatgc
    15601 gcgctcttgg atgctcggtt gcccagatcg ccgccgagat gtcccgcagg ttcaacctgc
    15661 ggccccgcgc ggcgtggcgg cacgcgttgg gctggccgca gtggaagctg gcgcaggagt
    15721 acaacaccgc ccatcccggc gccaagctgg cagacaatcg gatcagcgag tacgagagct
    15781 ggccgcacgg gggtaccgcg ccaagcgtgc gctacctgtc caatctcgcc gcgaccttcg
    15841 gccacggctg cacacccgcc cacctcgtcg acgtcgacga catggaacat ctcagtccca
    15901 cagaccgcag gctcttggcc ccggccgggg acgcgctcat ggtgtccagc gcgaacatcg
    15961 cgccgttccc cgagacccac cctgatctcc ggcttgcgag ccggaacatc aacactgtcg
    16021 gcagccgggg aaaccgtcgc gtggtacgcc gcgacgctcg ggggctgcca atccgcgagg
    16081 aggtagtcat ggccgccgag gaatccgccc agttccgacg ctggagcgcc accaccaacg
    16141 tcgatgacga agtgctggag cagatggcgg ccgacatcgc agaggtcgcg tcgagctatc
    16201 tcaccgatcc gcccgcgacc gtgttctccc gactgatcgg cgcccgcgac gacgtgttcg
    16261 ccttgatcgc cggacgccag cacccgcgcc acagcatgga gctgtacaag atcggcggac
    16321 agatgtgcgc gctgctcgcg cacgcctccg ccgatctggg ccacccgcac gccgcgaaca
    16381 cccacgcccg caccgcgctg cattgcgccg aagtcgccag ctacaccccg ctgcgggtct
    16441 acacccgatg ggtgcagagc aacgtcgcct actgggacgg ccgctatgac gacgcggccg
    16501 gactggtcga ggccgcgttg cccgacgcca ccagcgggac ggcactgcta cgactgacca
    16561 gccagcaggc caggatcaac gccgcccgcc aagattccgc aggtgtcgtt cgggcgctgg
    16621 ccgccgcgtc cgccgccccg accgacccca ccgcagacga accgggcgtg ttcgccttcg
    16681 ccaccggcaa agcggcctac tacgccagcg aagctcaccg ggaactcggc ggtgacaaac
    16741 acctcgatgc cgccattgac tgggcactta ccgccgtcaa cgagttcgcc gcggaacgcc
    16801 accccaatgc ccagttcgtc gccgccgccc gcatcgacct cacccgcgcc cacctggccc
    16861 gcggcgacct cgacgcggtg ggcgagcact tggctccggt cttgtccact gtggccgagc
    16921 agcgcaccgt cccggtgatc agccgcgtca ggtcgttgac caccctgctg agcggccacc
    16981 cgggcatcga gtcctccact gtggcctctt tgcgcgatga tctcgccgag ttctgttcca
    17041 ctccggcggc cagtccgtcg gagctgaact cggccgactg acccgctcac aaccgggagg
    17101 tgtgaacgtg cccgtgcaag tcgctgtctg cggaccacgc cactgcactg agcaggacca
    17161 ggccgacgcc cagcaggtgg gcaaactgct ggcccaggcc ggtgcgacgg tgatctgcgg
    17221 cggcggcacc ggagtgatgg ccgctgtcgc cgcgggcgcc cgcgccgaga acggcctggt
    17281 catcggcatc cgccccaacg actccaccga aggggccaac cccgacctgt cggcggtgat
    17341 cgtcaccaac atgggcgaag cccgcaacgc cgccatcgtc tggtccgccg acgccgtcat
    17401 cgcgatcggc ggctcgtggg gcaccctgtc cgagatcgcc ctggccaaac gacgcggcgg
    17461 cattccggtc atcactctga acggttggac cgtcctcgac cacgacggca acccgttgcc
    17521 agacaccaca cttacggccg acagccccca agacgccgtc gatcttgccc tcaacggcag
    17581 ccgctagagc acgtcgcgat cgtctgacaa tgtcgtgatg atcgaggccg tgaccactcg
    17641 gtagcggctg ccgacccgca gcacccttgc cggaaactcg ccccgcgcta tcaactcgta
    17701 ggcatggctg cggctcagac cgaacgcggc tgctgcttcc ggcaccccca ccgcagcggg
    17761 ccaagtctcg cggatctcgc tcagcgtcgg cgttctactg agcttgttca cctcatctga
    17821 catgttcccc ccatcgacga tgtccgggca tgatacaact aagtcattgc catgtcatcg
    17881 tagtctgggg aggatcgtgg cgcgtcaacc gaaggacttc cggatcgcgt gggcttccgc
    17941 cgagccctcg gcgccactcg gctatctctt gactggcccg gaaaccgcca ttcccatgcg
    18001 gtttcgcgcg tcgatcacgc tggagacacc tcccgcgacc gtgacgatcg aggtgttcgt
    18061 cggagccgac ctgcggccaa gagtccacga gttggccatt cggtcgaaca cccagttcca
    18121 gatcaccacc acggtgctgc gccaagtgct ggtcgagcaa ctgctccggg aagcggtggc
    18181 gaaggccgag gtcccggtaa gcgccctccc gccaggcgcg atcttgggcg cgcccccgca
    18241 acccgaagtg gcacatggga aagccgagac agacgcgcag accgcggccc gggtctactc
    18301 ccaggcagtc acatccggca gccccgcgcc cgcgatggcc gtggcccggg agatggggcg
    18361 gtcacgggcg caagtcgccc gctacctgcg caaggcccga cagatggggc tcctgcccga
    18421 actcgcacca ccaggtgtgg agaacgatcg agaggaagga cagacgcacc agtgagtgat
    18481 ccgatcaaga agatcacgtt gaagagcgga gcggtgagat accgcttcgt catcgatgtc
    18541 gggcgtgacc cggagaccag ccggaggctg cagaagacct tcaccttcga caccaagcgg
    18601 gaagcccgcg ccgagtacga caagatccgg caccaaacca acgagggcag ctacatccgg
    18661 cctgccaagg tcaccgtggc cgagtacctg accggctggc tggaaggcgc cacccgggat
    18721 ctccgggact ccagcaagag gagctaccgg gatgcgctcc gaccggcctt cgagcggctg
    18781 ggtccgacag cgatgcagaa ggtcaccaag gccgacatcg agcggatggt cacctggatg
    18841 gcgaccgagg gcaggcgacg cggcggaaag ccaggcaccg gcctcggccc gcgcagcatc
    18901 cagctcacgc tcggacggct caccgccgcg ttcgagatgg cgacgctgga gggcctgatc
    18961 cccaggaacg tggccaagct ggtgaaaccg cccaagtacg agcctgctga gccggagacc
    19021 tggtcgaagg ccgaggtgca caggttcctg accaaggcca agaaggatcg cctccatgcc
    19081 gcctggcggc tctcgctcta tggccttcgg cgcggcgagg tcttgggcct gcgatggaag
    19141 gacgtggact tcggaccgtt cagcgctgtg tgcgggaagc acagcgaacg ttggtgtgcc
    19201 gagtgctacg gcgccaagca cgccaccgtc catgtgcggc agtcgcgagt gctggtcgag
    19261 ggcaagatcc tgatcgagcc gcccaagtcc aggaacgggt tccggaagct gccgctcgac
    19321 gcccgcttgg ccgtcgcact gcgggcgctc aaggtcgcgc aagcggccga gaagctggcc
    19381 gcgggcgaag gctatgtcga cagcggctac gtggtcgtca acgaacttgg ccagcccgtt
    19441 caccccgagt ggtactccga cgagttccag cggctgtcga agcgcgccgg agtcaagcgg
    19501 atcgtcctcc acgaggggcg gcacaccacg ctgagcctga tggagaaggc cggggtgccg
    19561 atctccatca tcagcaagtg ggccgggcac tacgacacgg cgttcaccta ctcaacctac
    19621 gtgcacgccg acgacgaaga cctcaaaacc ggcaccgacg ccctcggcag gatctacaag
    19681 taagcagtac aagcgttcgt gtgacactgt gagacaacga ggccggaaac agaacaagac
    19741 ctcgtcccca taactgagaa caaggccctg acctggactt acttggtgcg cccgaaggga
    19801 ttcgaacccc taaccttctg atccgtagga cttcggtcca ccgttccaca gagtcccgct
    19861 tgcgtgtttt tcctggtcac ctgcggtatg tgcagcagta gcttttaccc gaacgggcga
    19921 ggactgagac ggcgattgag acggctcagg aagccccctg cctggagcgt gccagccgct
    19981 ggcgtggcgg cgcgaaggct gtcaccgtag gtggatgagg atggtgacgt gcccggactg
    20041 ccatgggtca ggcttgcaag acccgcccgc gaacgagagc gacgacgacg gcagtccccg
    20101 cggtaagtgc tcgggttgcg gcggtctcgg gcaggtgccc ggatgaacac ggtcgaacgc
    20161 accacgccac cggaagatgg cccagactgc cgaatctgcc gcgacacagg cgtcatgacc
    20221 tggcaacaac cagtgcaacg gcccgacagc ggctgggaaa tgcgcgaagt ctcccaccca
    20281 tgcacctgcg ccgcagcacg cgcggcaggg acttggcggc acccagcggc ggaacagaac
    20341 ctggtagtcg acgtccccga ccaccaggcc gccacgaatg cggcgccacc gcccacccgc
    20401 gcacacgggc acgccgacgc ggcccaggaa ctccccgacg cactcgccgc cctaatccag
    20461 gccgccatac gccgcgccga aggacacatc gactagctac tacgcgtctc cgccattacc
    20521 cacgctaggt aatccgggtt ccccagctca atcggccacg ccaccacaca tggaacgtca
    20581 tacggatgac gcgcatttgc gagcgagata atcgcgtcta cgtgcaccga acgagtgtgc
    20641 agcgcaatac gcgcctcagc cttatcgtgg atatcacctt gccatcgata tagggatcga
    20701 acccgttcga tcgaatgacc acccgcgcat agccgctcat cgaggagcat cctcgcaaac
    20761 tcagccaacc aatcagcgtc gggcgcggtg atgacgactt ccacaacgtc agacactgtc
    20821 cgcattccct tcgagttcgg agatgatgcc gcgcgcacca tcttcactct tggccacccc
    20881 gccccaccca gtgatgatct ttccgtcgta gctcaaaccg acccagcggc cgcgcatggt
    20941 gagtccatgc ggatgcaaca cgaaatagaa agtacctttg gagcgaacgg agccgtcagc
    21001 agcggcatac caccccatga ggatctcatt atcccatagg cgcaattcac cctgccaatg
    21061 gtagccgccg tcctcgacct caattcccct cgttgtcgtg cgaacgctca gcaaatcacc
    21121 ctgttgccca atgcgtactt cctgggccgt gatgacctca acgccgtctt tccacgtttg
    21181 ccaagacgcc caccactccc ccgacagact cagccgctga gaagtcattc cggccagttc
    21241 gttgacggtg atcttgagcg cgtccgcgat cgctacagcc acaggcaaca cggggtgctg
    21301 ctcccctgct tcgtaccgcc tgatctgccg cgtctggacg cccacagccg ccgctagctc
    21361 agcctgggac atgcccaggt cagcgcgacg ttccttcatc acttctgcca tctcgctcat
    21421 gcgtcccatc atgaggggtc tagttggtcc ttgacaacag gaccgaccgg accccaccat
    21481 aggggacgta agagacccca gagaggtctg aaaagccctg aacggtgtgg caacaccgtt
    21541 cagggcgcac atcgagcttg ggagagccgc gatgcaggtc gagagtactc ggatgttccg
    21601 ggtgaaagca gtggccgaca tgttggacgt ctcggtcaac acgatctacc gggccgtgga
    21661 gaccggcgag ctgaacgcgt tgaagatcgg caaggcgctg cgtatcccgg gggctgcgct
    21721 gaacgcctac ttgagccagt gcgcggagcc ggtcgacgcc caggtgctca gcgaccaggt
    21781 ggcttccgtc gccgacgcgg gcacggccca ggacgcggcg atcacgagcg aggtgtcccg
    21841 atgaccacga ccacgaccac gaacgtcgag caggaagacg cgtcggtggg cgcccgcctt
    21901 ctgcgggagt tgcgggtggg tgaggtcgcg ttggcgattc accacagcgg cgcgaagttg
    21961 caccgtgagt tgagcgacga cgagatcacg gtgttggtgg gccagggcgc ggcctgggtg
    22021 ggtgtggagc ggttgcgtct ggacgccgag tacgcccgtg aggtcacccg gcgcggtgac
    22081 ctcacccggc acaggcggtt gtgggggtcc cgcgcccgtt accagttgtg cgtggatctg
    22141 gcgtggcagg tgtcggcgga tcgcgcgtcc taccgggcgg cggctgccgc gttccgggcg
    22201 agccgcaagg gtgcgggccg ggggcatgcg gcatgagcga ccagtacccc accctgaccc
    22261 cggtggttga tgcggtggtg acggcgttgt acctgtcgcc gttcgagccc gaccaggtgc
    22321 ccgcgctcgg tgccgaccgg gtggcccggt acgtggcccg gatggcgctg ctgccggagt
    22381 tcgacgccct gatcggcgtg ctccgcaagc acgggcaccc gggcagccgg tacgtcgacc
    22441 acgcgcgtct ggtcgcgtgt caccgggccg cgcgcctggt gcgtcggtcc tcccgccgtc
    22501 gcgggcaccg gcagcgctga cccacccccg caccgccccc ttgtaccgcc cccggtcctg
    22561 tctgccgggt gatccgccgc gcctgtcgtc gcgcactgag gagtcttgtc gtgtccatgc
    22621 ctgtaccgcc gtcccatgac cccgccgacc cgtggctgta cccggtgacc gcaccggggg
    22681 cggacccgtg gacggaaccg gtgggggatc tcgcccccgt ctacgccctg ccctcggtgc
    22741 tgaccagcac cggcaccggc accggtacgg gtaccggtgc tggtgcgctc gacgacgcgg
    22801 ccatgggtga gcgtgtcgcg cggattcggg ggtggctgcc cccggtcgac ccggccgtgt
    22861 tcgggtgctt tttggggcag ttggccaccc acctggaccc gttcaccgaa gccgacccgg
    22921 tgggggtact ggtcaccctg ctcgccgccg ccggggtcca catgggtccg ggtccgcatg
    22981 tggtcgtcgg ggggttcgag cggcacccgt tgctcacgtg gccgatcgtg gtcggcccga
    23041 ccggtaccgg tcgcaaaggg accgggtaca acgtggccaa agccctgctc tcccacgcca
    23101 tccccgagtt cgtcgcggac aacgtccact ccggtctgtc cagcggcgaa gggctggcct
    23161 cggtgttcgc caccgacgac acccccggca agggcaagcc gcgactgctg cccgagcacg
    23221 acgtccggct actggcctac gaacccgagt gggcatcggt catggcccgc atgaaacgcg
    23281 agggcaacac cctctccgcg accctgcgcg cggcgtggga gggcgggaac ctgtccactc
    23341 tcaacgtcga tgcccgcacc gcccgacagt cccacgtcgg gatcgtcgcc cacatcaccc
    23401 ccaccgagtt ccgcgaccgc gtcagctcca ccgacatggc cggaggcacc tacaaccggt
    23461 tcctgcccat cgcggtcgcg cagtcgaagt tcctgcccgc ccccgacccc atcgacccca
    23521 cgaccctgct ccagttcggc gcggccctgt ccgaccgcct ggccgccgcg tcccgactcg
    23581 acgcgctcac cctcgacccc gacgccgcgc agctgtggcg tcgcctctac gtcgacttct
    23641 cggccgcagc cgacggcgac ggtgacggcg tcctggccca attcaccagc cgcgccgtgc
    23701 ccaactgcct tcgcatcgcc gccacctacg ccgccctcga ccgaaccgac cacatcacca
    23761 ccacccacct caccgccgcc gccgcactcg tccgctactc catcgactca gcccgcgtcg
    23821 tcctacggcc caacgacgac ctggtgaagc tgctgaccca catccgcgag cacggtccgc
    23881 agggatgcac ccgcgagcag gcccgcgatg ccttccagcg caacaagtcc gccgccgacg
    23941 tcggtcgcct gctggaccac ttggtcaccg caggacaggt cacggccacc agccgaccac
    24001 cagccggggg gaggggacgc cccgccacgg tcttcaccgc gaccacccca cgcggttgac
    24061 gcggttacgc gggaactgcc ctgaccagcg cgaacgccaa ccactaaccg cgtacccgac
    24121 gcggttagtc cagaacaaaa ccccagctca ggccacttac cgcgtaaccg cgtcaaccgc
    24181 gtgccacccc agaccaccat ccgccaggcg cggcccggac agccacagca ccccaccgag
    24241 ccgaccagac caatcaccga cgaaacccag gaggacagcc acc
//
