LOCUS       NZ_FMZZ01000002        21044 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinokineospora iranica strain IBRC-M 10403, whole genome shotgun
            sequence.
ACCESSION   NZ_FMZZ01000002
VERSION     NZ_FMZZ01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora iranica
  ORGANISM  Actinokineospora iranica
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101685.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 15:26:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,202
            CDSs (total)                      :: 6,139
            Genes (coding)                    :: 6,038
            CDSs (with protein)               :: 6,038
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 25 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 7 of 103
            Pseudo Genes (multiple problems)  :: 18 of 103
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:38:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 492444
            Orig. end                         :: 513488
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMZZ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            13..1035
                     /locus_tag="BLS56_RS07635"
                     /old_locus_tag="SAMN05216174_102473"
     CDS             13..1035
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025878.5"
                     /locus_tag="BLS56_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102473"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_091449203.1"
                     /transl_table=11
                     /translation="MIETVFRTEDVPAADRLAYWRELLSRTHAPMDLTSDNPEYFHACQ
                     RTLSFGAVSVWPVTFHAVTFHRTPKLIRQSDPDVYHLSLVLNGAATASWGDREISYGPY
                     DLHYNSSSQPCTIWTGGPANVIKSVGVEVPKSLVPLPRRSANDVIGRPLSGRTGIGALL
                     AGFLVRLTENTSGYQAGDEPRLGTVLADLVAALFAHTLEADRALPPETYRRTLLMRVQS
                     FIRQHLHDPDLSRDSIATAHHISTSYLHRLFQENGETVMGWIRRQRLEHARRDLADPTQ
                     RMVPVHRIAARWGFVHHADFTRSFRTAFHTTPSEYRRETLRPTGTRVIHRVDRMGNGGH
                     "
     gene            complement(1204..4071)
                     /locus_tag="BLS56_RS07640"
                     /old_locus_tag="SAMN05216174_102474"
     CDS             complement(1204..4071)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="BLS56_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102474"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_091449204.1"
                     /transl_table=11
                     /translation="MALIERHRELTTLTRLYADCVRARGRVALVSGGVASGKTALLAEF
                     AEHMVADGAILLTATGARAEHAVPFGVVTQLAQSPALPRAVADHISDLLSGDGSAAIEA
                     TTATADPVAIGRAGARVLDGVCAALLDLAKDRPVVIEVDDVQFADGPSQQALLYLHRRM
                     RFARVLVVLTEWALPRPTQAAFRAEVTRQPNTTHLRLAPLTRAGVADLLATRLDPAAAR
                     ALAPALHAVSGGNPLLVKALIDDQSAGTEHRARVAVGREFAQGVLACLHRWEPVLPAAA
                     RAVALLGDAGTPDLVGALLEITPDSAAQALDVLVTAGLLDDDKRFRHPVAATTVLDTLT
                     PAERGASHLRAAHLLYHQGAPADAVATHLTAADTAHGRAAGGEREDHAELADRGGFSDS
                     GDLGGPWAVAVLRHAAREDLVADRVELAVRRLELAARACADDAERADITTLLLRVEWRR
                     DPSAAARHLAPLRAARSAGRLADHNAVHLAKFLLWYGHTEELAGTLAGMAAAGELPAAG
                     QFSLVFHWLAFLYPPVVAGVPAPLPDQQAPVLADPWTRASAMLDRVRVGGARAEIVTAA
                     EHILQSCRLGEQTLGSQLSALAALVHADRNDRAAHWCAALLADATARGALTWQAVLGAL
                     RAEIALRQGDLPAAAEHARVAFDRLTGPGWGVAVGVPLSTRVAAATAMGKHDEAAALLR
                     APVPDAMFQTQFGLHYLHARGMHYLATDKPHAALGDFQRCGELMTGWDLDLPTLVPWRS
                     GAAQALLALGHRDDARALAAEQLTRPGNDGARTRGLSLRVLAAASPPDRRVGLLQEAVE
                     LLRAGGDRCELARALLDLSQAHNTTGDGEKARTLARRALQLAKACGAGPVNRDLVSRAA
                     LARAPLPEPSDHDAGLSTLSEAERRVAVLAALGHTNREIGGKLYITVSTVEQHLTRVYR
                     KLKVTRRTDLPAGLPGQLLAAADER"
     misc_feature    complement(1225..1227)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(1441..1443)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3826..3828)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4144..4158)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    complement(4258..4273)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            complement(4269..4673)
                     /locus_tag="BLS56_RS07645"
                     /old_locus_tag="SAMN05216174_102475"
     CDS             complement(4269..4673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685785.1"
                     /locus_tag="BLS56_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102475"
                     /product="hypothetical protein"
                     /protein_id="WP_091449205.1"
                     /transl_table=11
                     /translation="MADLRAATRGGPGRLLIAVYAVFALSACARSAVQIATRFDRAPLA
                     YLLSAIAAAVYVIATVGLAKGSRVSRRIAVVSCAVELAGVLAVGTASLVVPEAFPDATV
                     WSVFGRGYGFVPLALPVLGLAWLRHSARGQ"
     gene            complement(4666..5052)
                     /locus_tag="BLS56_RS07650"
                     /old_locus_tag="SAMN05216174_102476"
     CDS             complement(4666..5052)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685784.1"
                     /locus_tag="BLS56_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102476"
                     /product="hypothetical protein"
                     /protein_id="WP_091449206.1"
                     /transl_table=11
                     /translation="MIEPLSTALIWVAVGAALWALVLVLLNRPLPLDRRDGQLYLGLLG
                     LLELGLLGQAVAGFVKLAGAEHEVAGLSFAGYLLGALLILPVAVFWSLAERTRWGTAVL
                     VVGALVVPVMIVRLDQIWTAAGRG"
     gene            5150..5338
                     /locus_tag="BLS56_RS07655"
                     /old_locus_tag="SAMN05216174_102477"
     CDS             5150..5338
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS56_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216174_102477"
                     /product="hypothetical protein"
                     /protein_id="WP_091449207.1"
                     /transl_table=11
                     /translation="MGHHVDDVPVNGRGAGLDEVTMLPDEVRGHLLDCLTAPERLPDAL
                     PALREAAAALPAEEPVR"
     gene            complement(5775..6518)
                     /locus_tag="BLS56_RS07660"
                     /old_locus_tag="SAMN05216174_102478"
     CDS             complement(5775..6518)
                     /NRPS_PKS="Domain: PKS_KR (3-166). E-value: 4.9e-16. Score:
                     51.1. Matches aSDomain:
                     nrpspksdomains_BLS56_RS07660_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005457318.1"
                     /locus_tag="BLS56_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102478"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_091449208.1"
                     /transl_table=11
                     /translation="MIATVVVLGGRSEIGTAVARRLVAAGATTVVLAARRSDDLDTEEA
                     ALRQAGATKVSRVEFDADDLTTHEAVLTDIMSAHAPVDAVVLAFGILGDQPQAERDAAH
                     AVKIVHTDYVAHVSVLTHLANLLRRQGSGTLVVFSSVAGIRVRRANYVYGSAKAGLDGF
                     ASGLSDALHGSGVRLLLVRPGFVVGRMTSGMSPAPLSSTPTQVAKATVSALQRGRGEVW
                     VPWPLRPLFFCLRLLPRPLWRRMPR"
     aSDomain        complement(6021..6509)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS07660_PKS_KR.1"
                     /evalue="4.90E-16"
                     /label="BLS56_RS07660_PKS_KR.1"
                     /locus_tag="BLS56_RS07660"
                     /protein_end="166"
                     /protein_start="3"
                     /score="51.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVVVLGGRSEIGTAVARRLVAAGATTVVLAARRSDDLDTEEAALR
                     QAGATKVSRVEFDADDLTTHEAVLTDIMSAHAPVDAVVLAFGILGDQPQAERDAAHAVK
                     IVHTDYVAHVSVLTHLANLLRRQGSGTLVVFSSVAGIRVRRANYVYGSAKAGLDGFASG
                     "
     CDS_motif       complement(6102..6155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS07660_0002"
                     /evalue="3.80E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="BLS56_RS07660"
                     /protein_end="139"
                     /protein_start="121"
                     /score="0.3"
                     /tool="antismash"
                     /translation="HLANLLRRQGSGTLVVFS"
     CDS_motif       complement(6411..6509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS07660_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BLS56_RS07660"
                     /protein_end="36"
                     /protein_start="3"
                     /score="17.4"
                     /tool="antismash"
                     /translation="TVVVLGGRSEIGTAVARRLVAAGATTVVLAARR"
     misc_feature    6654..6669
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.9"
                     /tool="antismash"
     misc_feature    6656..6670
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            7029..8429
                     /locus_tag="BLS56_RS07665"
                     /old_locus_tag="SAMN05216174_102479"
     CDS             7029..8429
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685788.1"
                     /locus_tag="BLS56_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102479"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_091449209.1"
                     /transl_table=11
                     /translation="MTDTLPPIDRDGAAPQQSLGTAAARNLATTTKSVPQMQEITSRWL
                     LRVLPWTHVGGGTYRVNQRRTYLVGDGRITVDRTNAHARVVPGDLRELTFLRDFDDDED
                     TFATIAGLFTQEEYAPGDTLVEWGHAEDRFLIIAHGKVEKHAAGEYDDEPVVDVLADGE
                     YFDQWGLVEERIWDFTARAATRTTVLALRRADFQNLLERNDALRAHVEAVIAAGVDDSG
                     GEVPIDLAAGHEGEVELPGTFVDYEEFPREYELSVAQTVLRVHTRVADLYNQPMDQVEQ
                     QLRLTIEALRERQEHELVNNPEFGLLHNADVRQRIRTRTGPPTPDDMDELLAKVWKDPS
                     VILAHPRAIAAFGRECSKRGIYPSNVDIGGHKVPAWRGIPVLPCSKIPISDTRTTSIML
                     MRTGEAAQGVIGLHQVGLPDEYEPGLSVRFMGINDKAVTSYLVSAYYSAAVLVPDALGI
                     LEDVQIGL"
     gene            8476..9873
                     /locus_tag="BLS56_RS07670"
                     /old_locus_tag="SAMN05216174_102480"
     CDS             8476..9873
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685788.1"
                     /locus_tag="BLS56_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102480"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_228771449.1"
                     /transl_table=11
                     /translation="MTGLLDPDVTQHQQQSLSTSAARNLATTTKSVPQMQEITSRWLLR
                     MLPWVEARGAAYRVNRRLTYTLGDGRVSFTNVGAEISIVPPELRELSLLRGFDDDEALA
                     ELAGRFTQREFGPGEVIVRGGEPADTLHLIAHGKVTKFAPGHYDDEAAVAILADGEYFG
                     ERALIDQDTTWEHTVRTNTSCTVMTLSRQEFLALQERSPELREHVELIRAMPQPPRNKH
                     GEAEIALAAGHRGEVELPGTFVDYEMSPREYELSVAQTVLRVHTRVADLYNDPMNQVEQ
                     QLRLTIEALRERQEHELVNNRDFGLLHNADLRQRIHTREGAPGPDDLDELLSRRRRSDF
                     FLAHPRAIAAFSRECNRRGLYPATTEVQGRPVMAWRGVPLLPCDKIPISDTNTTSIIVM
                     RTGESDQGVIGLHQTGIPDEYQPGLSVRFMGISDKAVMSYLVSAYHSVAVLVPDALGVL
                     ESVQIGR"
     gene            10001..11044
                     /locus_tag="BLS56_RS07675"
                     /old_locus_tag="SAMN05216174_102481"
     CDS             10001..11044
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948854.1"
                     /locus_tag="BLS56_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102481"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_228771468.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-65, bitscore:
                     216.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTVEVQPPGHGSAREVLAHSRTLLDPALRAAVDTLPESMRHVAG
                     YHFGWWDEQGRAATADSGKAVRPAVVLTAAKAVGGTQAEALPAAVAVELVHNFTLLHDD
                     VMDGDRTRRHRPTAWSVFGLGSAILAGDALLTLAFDVLARSDHPNAQEGARILSAAVLA
                     VQDGQAADLAFEKRADVGLAECVRMAEGKTGALLGCSAALGALFGRAAPDQVDHLRGYG
                     ECLGLAFQLVDDLLGVWGDPSATGKPVYSDLENRKKSVPVVAALASETTAARELGSLYH
                     RKASLSAAELVRAAELIERAGGRSWTQTRANTLLSDAIDHLRAARPTPDAEAELTALAE
                     LACHRDH"
     gene            11161..12450
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="BLS56_RS07680"
                     /old_locus_tag="SAMN05216174_102482"
     CDS             11161..12450
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420544.1"
                     /locus_tag="BLS56_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102482"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_091449210.1"
                     /transl_table=11
                     /translation="MTATPALGPSDPLPAGAVLVARELQGITGAAEADAAVLRCPAAVL
                     VEGELRRQGVRSVGGVVDITAVRQNMDTTWVTLGDGGTGLGVVVRGGDRRARLAARSAM
                     GAWLAASGPRKVVLAAPRSFCAGIERAVDVVENVLEQREGPVYVRKQIVHNTHVVSDLE
                     SRGAIFVDDLDDVPDHATVIFSAHGVSPAVRAEAAERGMEVIDATCPLVTKVHAEARRF
                     AGRGDTVVLIGHAGHEEVEGTLGEAPERTVLVESVDDVLALDVPDPLRVSYLTQTTLAV
                     DETADIIAALRARFPALRAPGSDDICYASTNRQEALRDIASAADLVLVVGSANSSNSLR
                     LVELARRQGTPAYLVEDARDIRPDWLINNRIVGITAGASAPPRLVDEIVEALRGLGPTE
                     VTEHETSRETLQFTLPAGARNAGRCPDTPR"
     gene            complement(12413..13282)
                     /locus_tag="BLS56_RS07685"
                     /old_locus_tag="SAMN05216174_102483"
     CDS             complement(12413..13282)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016699943.1"
                     /locus_tag="BLS56_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102483"
                     /product="serine aminopeptidase domain-containing protein"
                     /protein_id="WP_091449211.1"
                     /transl_table=11
                     /translation="MSLSAQLGKRALGVATAVLLTAGTLVGTEAFADENPYQRGPEPTA
                     DALAADAGPFAVTRAAVPAGHGFGGGTVYYPSDDSQGTFAGIAVAPGYVESQSAVAWLG
                     PRLASHGFVVITIDTNTRFDQPESRGTQLLAALDYLTGSSAAKARVDPARLAVMGHSMG
                     GGGALSAAAKRPGLRAAVPLAPWSTSKDWSRVRVPTLVVGAERDAIASVGAHAEPFYQS
                     LGGEKAYLEMNEADHFVVNSATPTVGTFTVSWLKRFVDDDTRYEKFLCPAPSPSQLISE
                     YRDTCPHS"
     misc_feature    complement(13276..13286)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    13314..13331
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.08"
                     /tool="antismash"
     gene            complement(13422..13901)
                     /locus_tag="BLS56_RS07690"
                     /old_locus_tag="SAMN05216174_102484"
     CDS             complement(13422..13901)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013677879.1"
                     /locus_tag="BLS56_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102484"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_091449310.1"
                     /transl_table=11
                     /translation="MSGPGTDLARPRVAVTSAAPELYQKLIDLHVTAERQAVEAGLAAG
                     LVALVRVRASQLNGCAFCVDLHTSEAAGHGEDTRRLHALPVWRESGLFTARERAALALT
                     EAITLLAETRVPDAVYATAAAEFSEPELAQLVWAVTVINAFNRLAVTSRIGPRPR"
     gene            complement(13898..15544)
                     /locus_tag="BLS56_RS07695"
                     /old_locus_tag="SAMN05216174_102485"
     CDS             complement(13898..15544)
                     /NRPS_PKS="Domain: AMP-binding (51-448). E-value: 1.4e-55.
                     Score: 180.5. Matches aSDomain:
                     nrpspksdomains_BLS56_RS07695_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685772.1"
                     /locus_tag="BLS56_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102485"
                     /product="AMP-binding protein"
                     /protein_id="WP_228771451.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-51, bitscore:
                     168.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRKQAVWKTAAADRRRSKPGDLGTLFDDLLARGTKTVVHLSRP
                     LDLAPGHGTRYDIPALAALVRATAGWLHAAGVRPGDRVAVVKENHWDYVLLACAAARIG
                     AVPALLSDHLTPETAQILLKRLDPALLVTTCTVLDHARDNETDLTAFARRTVTLDGPHP
                     GTLPLADLRGHEPPPPVFRDADDPLVVNHTSGTTGMPKLVVHSTRTLIQGIAAAEATRL
                     PIVSSRKRDTVCSAIAYCHGRAIPWTASVLWLAPRKVVVIAEPEPHEAEPTLRAHPPTT
                     LEALPSTFVRWQPLAEGADNPFHDVRLYVSTFDAMHPPTVRAFLAATRRRPVWVQVWGQ
                     TETGPLTIRLLTRRSVAERDRRHPTTRNLGRPVPGRVRLRVVDPRTFQDVPTGRPGLVL
                     TRTRVRCLDYLGERDRWQAKASGPWWNTGDVGVRTRGGSYLLLDREVDVLPGQSCVELE
                     DVLEDRVPDAVECVVLGTPGRLPVPVVVTKNGVLDQDAWHDALRDLPALADPVVLTWDQ
                     VPRTGTGKVRRMELRSLIRSGQDTFGTGQWT"
     aSDomain        complement(14201..15391)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS56_RS07695_AMP-binding.1"
                     /evalue="1.40E-55"
                     /label="BLS56_RS07695_AMP-binding.1"
                     /locus_tag="BLS56_RS07695"
                     /protein_end="448"
                     /protein_start="51"
                     /score="180.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HGTRYDIPALAALVRATAGWLHAAGVRPGDRVAVVKENHWDYVLL
                     ACAAARIGAVPALLSDHLTPETAQILLKRLDPALLVTTCTVLDHARDNETDLTAFARRT
                     VTLDGPHPGTLPLADLRGHEPPPPVFRDADDPLVVNHTSGTTGMPKLVVHSTRTLIQGI
                     AAAEATRLPIVSSRKRDTVCSAIAYCHGRAIPWTASVLWLAPRKVVVIAEPEPHEAEPT
                     LRAHPPTTLEALPSTFVRWQPLAEGADNPFHDVRLYVSTFDAMHPPTVRAFLAATRRRP
                     VWVQVWGQTETGPLTIRLLTRRSVAERDRRHPTTRNLGRPVPGRVRLRVVDPRTFQDVP
                     TGRPGLVLTRTRVRCLDYLGERDRWQAKASGPWWNTGDVGVRTRGGSYLLLDREVDV"
     CDS_motif       complement(14927..14977)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLS56_RS07695_0001"
                     /evalue="4.10E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="BLS56_RS07695"
                     /protein_end="206"
                     /protein_start="189"
                     /score="13.4"
                     /tool="antismash"
                     /translation="VNHTSGTTGMPKLVVHS"
     misc_feature    15540..15555
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.15"
                     /tool="antismash"
     gene            complement(15547..16386)
                     /locus_tag="BLS56_RS07700"
                     /old_locus_tag="SAMN05216174_102486"
     CDS             complement(15547..16386)
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685771.1"
                     /locus_tag="BLS56_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102486"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_091449212.1"
                     /transl_table=11
                     /translation="MADAATGIAATVETNGSAGNTAQYVFGTAFQREDERLSLGERLWD
                     PGTISRLSTLGIGPGSRCLEVGAGRGSIAAWMAERGAAVTAVDIDTSRLDRLRGLGVAV
                     CQVDVRTGALPVAAYDVVHARLVVQHLGDRAAAVRALCAALRPGGHLVLEDTDTASLFS
                     HAAGPFHPEVKRAAYAVMVESGYHPRCGLLDVDLVTAAGLSDVRADGRAEVVRGGTPES
                     RWFALWLEHLRPAMLAAVKESSVSEMDIDRAVADLADPRHTWLSQVMVTVIGRKDVQ"
     gene            complement(16379..17704)
                     /locus_tag="BLS56_RS07705"
                     /old_locus_tag="SAMN05216174_102487"
     CDS             complement(16379..17704)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003091357.1"
                     /locus_tag="BLS56_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102487"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_091449213.1"
                     /sec_met_domain="DAO (E-value: 6.2e-08, bitscore: 27.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDLDVAVVGAGVAGLALAHRLRAAGRAVHVFESAEHVGGRMAS
                     LRRDGYLIDTGAEMIGSCGYPAMWRLIREFGMSEVEVPAIGADLAMWREGRAHPHVGDP
                     RGLLAGAALSRVSRLALVRLLGLAALRRKEYDTDAPEATPLGHRAIADVTRGDLHDYLF
                     QPLTGGFFGWDTERACAGPLLSHLLAVGPTSTFRTFRDGMDVLARKLAEGVEISTGVTV
                     DEVVATGSGARVFAGGAVVNARTVVLAVPAPVAAAVHAQAPDYVRACEFRPMIKVICLL
                     GRPVAPAGGGQSFALAVPTVENPELAGIVLDDRKHPGRVPPERGLVTLVAGPSVSAELL
                     SATDGEIAATLTEQAERYVPGLADALRATVVTRFRHGLPMPTPAAMAARPDFVRRPPST
                     VEYAGDWWLLRPSSEAAVRSAELVAERLAVPRTAGVSAVARG"
     gene            complement(17701..18654)
                     /locus_tag="BLS56_RS07710"
                     /old_locus_tag="SAMN05216174_102488"
     CDS             complement(17701..18654)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685769.1"
                     /locus_tag="BLS56_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102488"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_139190555.1"
                     /transl_table=11
                     /translation="MTATLSLTAAPGRVGAYARLAKLDVWDYYLALPLAWSLAGAAAWF
                     TPAVLGTLAAFGVGTVCVVSAAVAFDDVTGHRDGSDAANYGPDAPARKLARKPLLTGEL
                     AEADAIRFGWAAASAGALLWALAAVLAPFSALWTVGLLALCLVTAVQYSWGVKLSYHGW
                     QEVFLAGFGVGLVLVGVGLTAGAPSEFAVVQSVLFGLGPLLFGVYSNTRDADGDAAVGR
                     KTAAVLLSRQGNKAFIVALTLAEIALIVTAAGLGAAPWWFAIAMAPAVFLRVAQLRRGV
                     GLGDLLRARLLGLWAHRATVATLIAINLTIALGARP"
     gene            complement(18654..19778)
                     /locus_tag="BLS56_RS07715"
                     /old_locus_tag="SAMN05216174_102489"
     CDS             complement(18654..19778)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035202.1"
                     /locus_tag="BLS56_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102489"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_091449312.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.4e-98,
                     bitscore: 324.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRLPFFPPDLFDGERDVVLETVRRVGLADDQRFILGERTAAFEE
                     ALRVNTGAADVVACGSGTAALMLVLRAMDIGPGDEVVVPAFGCAPLAASVVNVGAVPVF
                     VDVHPWTMVVEPYEVEAAITARTAAIMPAHMFSVMADMPTMRELARRHDVRLIEDSAVA
                     QGGVLRGLQAGRWGEAGVFSFVQVKTFGSIGEGGAVVTDDPEIGRLARMLRNHGQDGKN
                     RFVHHLVGYNSRFDEIMADFQLHRLPGLAARLARRAEIADYYTERFAALGDRGVQAPPP
                     GREGRCFYVYSLLADRRDELKRHLASRGVGSHVYYPAPLPAQPAFAPYARPGQYWPHAE
                     LACARTLALPLYPHLTDAQVEHIADAVCDFPGGP"
     gene            complement(19787..20992)
                     /locus_tag="BLS56_RS07720"
                     /old_locus_tag="SAMN05216174_102490"
     CDS             complement(19787..20992)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685767.1"
                     /locus_tag="BLS56_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216174_102490"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_091449214.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.3e-111,
                     bitscore: 366.1, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHAATLAEPGTATPSGARVPFFTQAATFAALWPEIEANVAAVVE
                     RGKYSHGHAVGEFEAALGRVVDAAHVVGVNSGTDALVLLLRAAGLEAGDEVVVPAFSFV
                     ASASSVVLAGGRPVFADIDPVTYALDPAAAAAAVTARTRMLMPVHLFCQLADLGAVTRL
                     AERHALTVVEDSAEAIGMRWDGTHAGLHGAGGVLSFFPTKTLGALGDAGAVITNDDRIA
                     ETAAALRHHGRFGHTLDHFPGIGNETVLPGLNSKMDDVQAAVLLAKLGRLDADIARRAA
                     LAGAYTERLRGCPGVRRLPTVVEREAETNPVFYVYAVEVEHRDSLVAYLAAHHVGTETY
                     YPVPLHRQPCFADLGHRPGEFPHAEAACARTVALPLYPDLTEAQVDRVCELIRAFYGGS
                     RS"
     misc_feature    complement(20015..20017)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tatcctggac cgatgatcga gacggtcttc cggaccgagg acgtgcccgc cgccgatcgg
       61 ctggcctact ggcgcgagct gctcagccgc acgcacgccc cgatggacct gaccagcgac
      121 aacccggaat acttccacgc ctgccagcgc acgctgagct tcggcgcggt gtcggtgtgg
      181 ccggtcacgt tccacgcggt gaccttccac cggacgccga agctgatccg ccagtccgac
      241 cccgacgtct accacctctc cctggtcctc aacggcgcgg ccacggcgtc ctggggcgac
      301 cgggagatca gctacggccc ctacgacctg cactacaaca gctcgtcgca gccgtgcacc
      361 atctggaccg gcggccctgc gaacgtgatc aaatcggtgg gcgtcgaagt ccccaagtcc
      421 ctggtccccc tgccccggcg cagcgccaac gacgtcatcg gccgcccgct gtccggccgc
      481 accgggatcg gcgccctgct cgcgggcttc ctcgtccgcc tgaccgagaa cacctccggc
      541 taccaggcag gcgacgaacc ccgcctgggc acggtgctgg cggacctggt cgcggcgctg
      601 ttcgcgcaca ccctcgaagc cgaccgcgcc ctgccacccg agacctaccg gcgcaccctg
      661 ctgatgcgcg tccagtcctt catccggcag cacctgcacg accccgacct gtcccgggac
      721 tcgatcgcca ccgcccacca catctcgacc agctacctgc accgcctgtt ccaggaaaac
      781 ggcgagaccg tcatgggctg gatccgccgc caacgcctcg aacacgcccg ccgcgacctg
      841 gcagacccca ctcagcggat ggtcccggtc caccggatcg ccgcccgctg gggcttcgtc
      901 caccacgccg acttcacccg ttccttccgc accgcattcc acaccacccc cagtgagtac
      961 cgccgtgaaa ccctgcgccc caccggcacc cgggtcatcc accgagtcga tcggatgggg
     1021 aacgggggcc actgacatca ctcccgacgc aggcatcgac cgaccggccc acaggctcaa
     1081 gctcgactga aagtacgttc aagacaccgt tccgattcgt aaacccgcag gtcaacaagt
     1141 gccttccccg cgcacgcggg gctgttccgc ctcggccgcg agggtgcctg ccgagtcact
     1201 agatcagcgt tcgtccgcag cggctaagag ctggccgggt aggcctgccg ggagatccgt
     1261 gcggcgggtg actttcaact tccggtacac gcgggtcaag tgctgttcga cagtgctgac
     1321 cgtgatgtag agcttgccgc cgatttcgcg gttggtgtgg cccagggccg ccaggaccgc
     1381 gacccggcgt tcggcttcgc tgagggtgga caggcccgcg tcgtggtcgg agggttcggg
     1441 taagggagcg cgagccaggg ccgcgcggga gaccaggtcg cggttgacgg ggcctgctcc
     1501 gcaggccttg gcgagttgca gggcgcggcg ggccagggtg cgggccttct cgccgtcgcc
     1561 ggtggtgttg tgggcttggc tcaggtccag gagggctcgg gccagttcgc agcggtcgcc
     1621 gcccgcgcgg agcagttcca ccgcctcttg cagcaagccc acccggcggt ccggcggcga
     1681 cgctgcggcc aggacgcgca gggacaggcc gcgggtgcgg gcgccgtcgt tgccggggcg
     1741 ggtgagctgc tcggccgcca gcgcccgcgc gtcgtcgcgg tggcccagcg ccagcagcgc
     1801 ctgcgccgcg cccgaccgcc acgggaccag ggtgggcagg tcgaggtccc agcccgtcat
     1861 cagctcgccg cagcgttgga agtcgccgag agcggcgtgc ggtttatccg tggccaggta
     1921 gtgcatcccg cgtgcgtgca ggtagtgcag accgaactgg gtttggaaca tcgcgtccgg
     1981 aacaggggca cgcagtagcg cggcggcttc gtcgtgcttg cccatggcgg tggcggcggc
     2041 gacccgggtc gacagcggca ccccgaccgc cacgccccag cccggcccgg tcagccggtc
     2101 gaacgcgacc cgggcgtgct cggccgccgc gggcaggtcg ccttggcgca gcgcgatctc
     2161 cgcgcgcagg gcgccgagca cggcctgcca ggtcagcgcg ccgcgcgcgg tcgcgtcggc
     2221 cagcagcgcg gcgcaccagt gcgcggcgcg gtcgttgcgg tcggcgtgga ccagcgcggc
     2281 cagcgcggaa agctgcgagc ccagcgtctg ctcgccgagc ctgcaactct gcaggatgtg
     2341 ctcggccgcg gtgacgatct ccgcgcgcgc gccgccgacc cggacgcggt cgagcatcgc
     2401 cgacgcccgg gtccacgggt cggcaaggac cggggcctgc tggtcgggca gcggcgcggg
     2461 cacaccggcc acgaccggcg ggtacaggaa cgcgagccag tggaagacca ggctgaactg
     2521 tcccgccgcg ggcagttcgc ccgcggccgc catgcccgcg agggtgcccg ccagctcttc
     2581 ggtgtggccg taccagagca ggaacttggc caggtgcacg gcgttgtggt ccgccagcct
     2641 gcccgccgac cgggcggcgc gcagcggagc caggtgccgg gcggcggcgg acgggtcgcg
     2701 ccgccactcc acgcgcagca gcagggtggt gatgtcggcg cgctcggcgt cgtcggcgca
     2761 cgcgcgcgcg gccagttcca gcctgcgcac cgcgagttcc acccggtccg cgacgaggtc
     2821 ttcccgggcg gcgtgccgca gcaccgccac cgcccagggc ccgccgaggt caccggagtc
     2881 ggagaagccg ccccggtcgg caagttcggc gtggtcctcg cgctcgccgc ccgcggcgcg
     2941 gccgtgggcg gtgtcagcgg cggtgaggtg ggtcgcgacc gcgtccgccg gagcgccctg
     3001 gtggtagagc aggtgggcgg cgcgcaggtg cgacgctccg cgctcggccg gggtcagggt
     3061 gtccaggacg gtggttgccg ccaccgggtg gcggaagcgt ttgtcgtcgt ccagcagccc
     3121 cgcggtgacc agcacgtcca gcgcctgcgc ggccgagtcg ggggtgatct ccagcagcgc
     3181 gcccaccagg tcgggggttc ccgcgtcgcc gagcagggcc acggcgcggg cggcggcggg
     3241 cagcacgggt tcccagcggt gcaggcaggc gaggacgccc tgggcgaact cccggccgac
     3301 ggcgacccgc gcgcggtgtt ctgtgccagc cgactggtcg tcgatgagtg ccttgaccag
     3361 caacgggttt ccgccgctca ccgcgtgcag cgccggggcc agggcacgcg cggcggccgg
     3421 gtcgagccgg gtggcgagca ggtcggcgac gcccgcccgg gtgagtgggg cgagccgcag
     3481 gtgggtggtg ttgggctggc gggtcacttc ggcgcggaag gccgcctggg tgggccgggg
     3541 cagggcccat tcggtgagga ccaccaggac gcgggcgaag cgcattcgcc ggtgcaggta
     3601 gagcagggcc tgctgggacg gcccgtcggc gaactggacg tcgtcgacct cgatgaccac
     3661 cgggcggtcc ttggccaggt cgagcagggc ggcgcacacg ccgtcgagca cgcgggcgcc
     3721 cgcgcggccg atcgcgaccg ggtcggccgt ggccgtggtg gcctcgatgg ccgcgctgcc
     3781 gtcgccgctc agcagatcgc tgatgtggtc ggcgacggcc ctgggtaacg cggggctctg
     3841 ggccagttgc gtcaccacgc cgaagggcac ggcgtgctcc gcgcgggcgc cggtcgcggt
     3901 gagcaggatc gccccgtcgg cgaccatgtg ctcggcgaac tcggcgagca gcgcggtctt
     3961 tccgctggcc acgccgccgc tgacgagcgc gacccggccc ctggcgcgca cgcagtcggc
     4021 gtagagccga gtcagagttg tcaattcccg gtgtctttcg atcagcgcca tgcgtcgccc
     4081 tcgtcgtgtg ctcacaattc cccgttacca gaatctatcg gcagcgtccg cacgtgtgga
     4141 agttttgcca attgacagag tgaacagtgt ggaacaatca ggtgagcaag cgcccgaatg
     4201 gagcaaggaa aatggcacga atgccgcacc aattccccgg ccgtcgaatc agcggcggaa
     4261 aataggcttc attgcccgcg ggcgctgtgc cggagccagg ccagtcccag gaccggcagc
     4321 gccagcggca cgaacccgta cccacggccg aacaccgacc agacggtggc gtccgggaac
     4381 gcctccggca cgaccaggct cgccgtgccc acggccagca cgcccgccaa ttccaccgcg
     4441 cacgacacga ccgcgatccg ccgcgacacc cggctgccct tggccaggcc gacggtggcg
     4501 atcacataga ccgcggcggc gatagcggaa agcaggtagg ccagcggcgc gcggtcgaat
     4561 cgggtcgcga tctgcaccgc cgaccgggcg caggcggaaa gcgcgaagac cgcgtacacc
     4621 gcgatcagga gcctgccggg gccgcctctg gtcgcggcgc gcaggtcagc cacggcccgc
     4681 cgccgtccat atctggtcga gccgcacgat catgaccggc accacgagcg ccccgacgac
     4741 cagcaccgcc gtgccccacc gggtgcgctc ggccagcgac cagaacaccg cgacgggcag
     4801 gatcagcagc gcgcccagca ggtagcccgc gaacgacagc cccgccacct cgtgctcggc
     4861 gcctgccagc ttgacgaacc cggcgaccgc ctgcccgagc agcccgagtt ccagcaggcc
     4921 gagcagcccc agatagagct gcccgtcgcg gcggtccagc gggagcgggc ggttgagcag
     4981 caccaggacc agcgcccaga gcgcggcgcc cacggccacc cagatcaggg cggtggacag
     5041 cggttcgatc atcgcggtgg acctcgtgcg ggtgtggcgg ccagcgggct gcccgaaagc
     5101 gtcgcacgcc gcaccgcacg ccacccgatc ggggccacgc cgccgtcacg tgggccacca
     5161 cgttgacgac gtaccggtca acggacgcgg cgccggactg gatgaggtga cgatgctgcc
     5221 cgacgaggtg cgcggccatc tgctcgactg cctgacggct cccgagcgcc tgcccgacgc
     5281 cctgcccgcg ctgcgcgagg ccgcagccgc gctgcccgcc gaggaacctg tgcggtaggc
     5341 gggtgcgctc cttctttccc actggcagca ggcaaagcga gggtgagtgc caggcaggtc
     5401 gcggggcggc ctggcggatg cgcggggtgc tgggtgggca aaccgccggg tgggtgaatc
     5461 cgcgcgcggc cagacaggtg gggatcggcc agacagatgg gagaccatgc ctgcgggctt
     5521 ggcagcggag aagacctgtc ggatggccca atagcggcag gtgggggcaa gcggcatcgc
     5581 gtcgaaccgt gccctgcgaa ggagcctttg ttcgcccgtt tcgccgcccc acggccccac
     5641 accaaagccc acccgccctg ggggaccgtc cctgatccat cctatcgtcg caggtcagcg
     5701 ggggggaaag agggggcggc tggccggtgg ataactcgcc gtcgtagggg acgtggcggg
     5761 ttccttggtg gaggtcagcg gggcattcga cgccagaggg ggcggggtag caggcgtagg
     5821 cagaagaaca gggggcgcag gggccagggg acccacacct ctcccctgcc ccgctgtagt
     5881 gcgctcaccg tcgccttggc cacctgggtc ggggtgcttg acaggggggc gggggacatt
     5941 ccgctggtca tccggcccac tacgaagccg ggacggacca ggagcaggcg aacaccgctg
     6001 ccgtgcagtg cgtcggatag gccgctggcg aagccgtcca ggcccgcctt ggccgaaccg
     6061 tagacgtagt tggcccgtcg gacgcggatg cccgctaccg aggagaagac caccagggtg
     6121 ccgcttccct gccgccgcag gaggtttgcc aggtgggtga ggacgctgac gtgggctacg
     6181 taatcagtgt gcacgatctt gacagcatgt gctgcgtcgc gttcggcttg gggttggtcg
     6241 cctaggatgc cgaaggcgag caccaccgcg tcgacggggg cgtgggcgga catgatgtcc
     6301 gtcaacaccg cctcgtgggt ggtgaggtcg tcggcgtcga actcgactcg gctcaccttg
     6361 gtcgcgcccg cctggcgtag ggcggcctct tcggtgtcca ggtcgtcgga tcgccgggcg
     6421 gccaggacga ccgtggtggc gcctgccgcc accaggcgtc gggcgacggc tgttccgatc
     6481 tcgctgcggc cgccgaggac caccaccgtt gcgatcattc cgcccagtgt gccgtccccg
     6541 cggatgccac gatcaggcgg gccgttcacc acttcgtcgc agtgcagtac aagatcgagt
     6601 gatagatcca ctcaatgact actgcaggtc tgcaccgggg ccgaatcggg tggtttgaca
     6661 gtggttatca ccagcccatt cggggactgt acggccacaa aattccggtg ctagcttcga
     6721 cccgttcgac aaccgaaggc ggcgaaacga catctcgagc actcaacggc gatctcgaga
     6781 cgacggcgat ccagaggcag atccataaac gacactgggg cagggacact gggggcaggg
     6841 ccaaaccggc agcctgcggc atcccggttc cgcatcctac ccgaaatccc ccattcccct
     6901 tcccccggac atggccgcct gcctggccac gcccacaacc ggcacgccca cccacccggt
     6961 caccggacgg acccgctctc aaacagatct tcggcaagca caagcacaac aggattggcg
     7021 gtagcacagt gaccgatacc ctgcccccca tcgaccgcga cggggccgcg ccacagcaga
     7081 gcctggggac cgcggcggca cggaatctgg ccaccacgac caaatccgtc ccgcagatgc
     7141 aggagatcac ctcccgctgg ctgctgcgcg tcctgccctg gacccacgtc ggcggcggca
     7201 cgtaccgggt caaccagcgc cgcacctacc tcgtcggcga cggccgcatc accgtggacc
     7261 gcacgaacgc acacgcccgc gttgttcccg gcgacctgcg ggaactgacg ttcctgcgcg
     7321 acttcgacga tgacgaggac actttcgcca cgatcgccgg gctgttcacc caggaggagt
     7381 acgccccggg cgacacgctg gtcgagtggg gccacgccga ggaccggttc ctgatcatcg
     7441 cgcacggcaa ggtcgagaag cacgccgcgg gcgagtacga cgacgagccc gtggtggacg
     7501 tcctcgccga cggcgagtac ttcgaccagt ggggcctggt cgaagagcgc atctgggact
     7561 tcaccgcccg cgcggccacc aggaccaccg tgctcgcgct gcgccgcgcc gacttccaga
     7621 acctgctgga gcgcaacgac gccctgcgcg cgcacgtcga ggccgtcatc gcggcgggcg
     7681 tcgacgacag cggcggcgag gtcccgatcg atctcgccgc gggccacgag ggcgaggtgg
     7741 agctgcccgg cacgttcgtg gactacgagg agttcccccg cgagtacgag ctgagcgtcg
     7801 cgcagaccgt cctgcgcgtc cacacccgcg tcgccgatct ctacaaccag ccgatggacc
     7861 aggtcgagca gcagctgcgg ctgaccatcg aggcgctgcg cgagcgccaa gagcacgaac
     7921 tggtcaacaa ccccgagttc ggcttgctgc acaacgccga cgtccggcag cgcatccgca
     7981 cccgcaccgg cccgcccact ccggacgaca tggacgagct gctcgccaag gtgtggaagg
     8041 acccgtcggt catcctggcc cacccgcgcg cgatcgccgc gttcggccgc gagtgcagca
     8101 agcgcggcat ctatccatcc aatgtggaca tcggcgggca caaggtcccg gcctggcgcg
     8161 gcattccggt gctgccgtgc agcaagatcc cgatcagcga cacccgcacg acctcgatca
     8221 tgctcatgcg caccggcgag gcggcccagg gcgtgatcgg cctgcaccag gtcggcctcc
     8281 ccgacgagta cgagcccggc ctgtcggtgc ggttcatggg gatcaacgac aaggccgtca
     8341 cctcgtacct ggtgagcgcc tactactcgg cggcggtgct ggtccccgac gccctgggaa
     8401 tcctcgaaga cgtccagatc ggcctctgac ccagcgccgc accgatttcc gacttaccga
     8461 ttggcggtat cacgcgtgac cggtctcctc gaccccgatg tcacccagca ccaacagcaa
     8521 agcctgagca cctcggccgc gcgcaatctg gccaccacca ccaagtccgt cccgcagatg
     8581 caggagataa cctcccgctg gctgctgcgg atgctgccct gggtcgaggc caggggcgcc
     8641 gcgtaccggg tgaaccggcg gctgacctac accctcggcg acggccgggt cagcttcacc
     8701 aacgtcgggg ccgagatctc gatcgtcccg ccggagctgc gggaactgtc gctgctgcgc
     8761 ggtttcgacg acgacgaggc gctggcggag ctggcgggcc gcttcaccca gcgcgagttc
     8821 ggccccggcg aggtgatcgt gcgcggcggc gagcctgccg acacgctgca cctcatcgcg
     8881 cacggcaagg tgaccaagtt cgccccgggc cactacgacg acgaggccgc ggtcgccatc
     8941 ctcgccgacg gcgagtactt cggcgagcgc gccctgatcg accaggacac cacctgggag
     9001 cacactgtcc ggacgaacac gtcctgcacg gtgatgaccc tgtcccggca ggagttcctg
     9061 gcgctgcagg agcggtcccc cgagctgcgc gagcacgtgg agctgatccg cgcgatgccg
     9121 cagccgccgc ggaacaagca cggcgaggcc gagatcgcgc tggcggcagg ccaccgcggc
     9181 gaggtcgagc tgccgggcac gttcgtggac tacgagatga gcccgcgcga gtacgagctg
     9241 agcgtcgcgc agaccgtgct gcgggtccac acccgcgtcg ccgacctcta caacgacccg
     9301 atgaaccagg tcgagcagca attgcggctg accatcgagg cgctgcgcga gcgccaagag
     9361 cacgaactgg tcaacaaccg cgacttcggc ctgctgcaca acgccgacct gcgccagcgc
     9421 atccacaccc gcgagggcgc gcccggcccg gacgacctcg acgagctgct ctcccgcagg
     9481 cgccggtcgg acttcttcct cgcccacccg cgggccatcg ccgcattcag ccgcgagtgc
     9541 aaccggcgcg gcctctaccc ggccaccacc gaggtgcagg gcaggccggt gatggcctgg
     9601 cgcggggtgc cgctgctgcc ctgcgacaag atcccgatca gcgacaccaa cacgacctcg
     9661 atcatcgtca tgcggaccgg cgagtccgac caaggggtga tcggcctgca ccagaccggc
     9721 atcccggacg agtaccagcc gggcctgtcg gtgcggttca tgggcatcag cgacaaggcg
     9781 gtcatgtcgt acctggtcag cgcctaccac agcgtggcgg ttctggtccc cgacgcgctc
     9841 ggcgttctgg aaagcgtcca aatcggacgg tagatgtgat gaccggactg tggtgatcgg
     9901 gtactgatcc cgtcgttcac ccgccaggcc caccttgacg ttcccggccg gttcccggcc
     9961 gggaacgtcc acaagagacc gcagaaggga ccgaatcgtg ctgcccaccg tcgaggtgca
    10021 accaccaggg catggctccg cgcgggaagt gctcgcgcac agccggaccc tgttggaccc
    10081 ggccctgcgc gcggccgtcg acacgctgcc cgagtcgatg cgccacgtcg ccggatacca
    10141 cttcggctgg tgggacgagc agggccgcgc cgcgaccgcg gacagcggca aggcggtgcg
    10201 gcccgcggtc gtgctcaccg cggcgaaggc cgtcggcggc acgcaggccg aggcgctccc
    10261 cgccgccgtc gcggtggaat tggtgcacaa cttcactctg ctgcacgacg acgtgatgga
    10321 cggcgaccgc acccgcaggc accggcccac ggcgtggagc gtcttcggcc tcggcagcgc
    10381 catcctcgcc ggtgacgcgc tgctcaccct cgccttcgac gtcctggccc gcagcgacca
    10441 cccgaacgcc caggaggggg cccgcatcct gtccgctgcg gtcctggccg tccaggacgg
    10501 ccaggccgcc gacctggcct tcgagaagcg cgccgacgtc ggcctggccg agtgcgtgcg
    10561 gatggccgag ggcaagaccg gagccctgct gggctgctcg gccgctctcg gcgccctgtt
    10621 cggccgggcc gcgcccgacc aggtcgacca cctgcgcggc tacggcgaat gcctcggcct
    10681 cgcgttccag ctcgtggacg acctgctcgg cgtctggggc gacccgtcgg ccaccggcaa
    10741 accggtgtac tcggacttgg agaaccgcaa gaagtccgtg cccgtggtgg ccgccctggc
    10801 ctcggagacc accgcggccc gcgaactcgg ctcgctctac caccgcaagg cgtcgctctc
    10861 ggcggccgaa ctggtgcgcg cagcggagct catcgagcgc gcgggcgggc ggagctggac
    10921 ccagacccgg gcgaacaccc tgctctccga cgccatcgac cacctccggg cggcccgccc
    10981 gaccccggac gccgaggccg agctcaccgc cctggccgag ctggcctgcc accgagacca
    11041 ctgatccccc cttgtccccc ttgcgccctg gtcccccctt gcccgacccg gcaggccgtc
    11101 gcgccgccgt cactggtgac tgtcacatcc gaactgtgct atccgaggag atccgagtcg
    11161 atgaccgcaa ctccagcgct gggcccgtcc gacccgctgc ccgcgggtgc cgtccttgtc
    11221 gcccgggagt tgcaaggcat cactggcgcc gctgaggccg atgccgccgt gctcaggtgt
    11281 ccggccgcgg tgctggtgga gggcgagttg cgcagacagg gcgtgcgcag cgtcggcggc
    11341 gtcgtggaca tcaccgcggt ccggcagaac atggacacca cctgggtgac cctcggcgac
    11401 ggcggaaccg gcctgggcgt ggtcgtgcgc ggcggcgacc ggcgggcccg gctcgcggcc
    11461 cgctcggcga tgggcgcgtg gctggcggcc agcggcccgc gcaaggtggt cctggccgcg
    11521 ccgcgctcgt tctgcgccgg gatcgagcgg gccgtggacg tggtcgagaa cgtgctggag
    11581 cagcgcgagg ggccggtgta cgtgcgcaag cagatcgtgc acaacacgca cgtggtgtcc
    11641 gacctggagt cccgcggcgc gatcttcgtc gacgacctgg acgacgtccc ggaccacgcg
    11701 accgtgatct tctccgcgca cggcgtgtcc cccgccgtgc gggcggaagc cgccgagcgc
    11761 ggcatggagg tcatcgacgc gacctgcccg ctggtcacca aggtgcacgc ggaggcccgc
    11821 cggttcgccg gtcgcggcga cacggtcgtc ctcatcggcc acgccgggca cgaggaggtc
    11881 gagggcaccc tgggcgaggc gccggagcgc acggtcctgg tggagtccgt ggacgacgtg
    11941 ctggccctcg acgtgcccga cccgctgcgg gtgtcatacc tgacgcagac gaccctcgcg
    12001 gtggacgaga ccgccgacat catcgcggcc ctgcgcgccc ggttccccgc cctgcgcgcc
    12061 cccggctcag acgacatctg ctacgcctcg accaaccggc aggaggcgct gcgcgatatc
    12121 gccagcgccg ccgatttggt tctggtggtc gggtcggcca attcgtccaa ctcgctgcgg
    12181 ctggtcgaac tggcccgccg ccagggcacc ccggcctacc ttgtcgagga cgcccgggac
    12241 atccggccgg actggctgat caacaaccgg atcgtcggca tcaccgctgg cgcgtccgcg
    12301 ccgccccgcc tggtggacga gatcgtcgag gcgctgcgcg gcctgggtcc caccgaggtc
    12361 accgaacacg agacgagccg ggagaccctc cagttcacgc tgcccgcggg cgctaggaat
    12421 gcgggcaggt gtcccgatac tccgagatga gctggctcgg gctcggcgcc gggcacagga
    12481 acttctcata acgcgtgtcg tcgtccacga aacgcttcaa ccaggacacc gtgaaagtgc
    12541 cgaccgtcgg tgtggcggaa ttgacgacga aatggtccgc ctcgttcatt tccagataag
    12601 ctttctcgcc gccgaggctc tggtaaaacg gctcggcgtg cgcgcccacc gaggcgatcg
    12661 cgtcccgctc ggcgccgacc accagcgtcg gcacccgcac ccgcgaccag tccttgctgg
    12721 tgctccacgg cgccagcggc accgccgccc gcaggccggg ccgcttcgcc gcggcggaca
    12781 gcgccccgcc gccgcccatc gagtgcccca tcaccgcgag ccgcgccggg tccaccctgg
    12841 ccttggcggc actggacccg gtcaggtagt ccagcgccgc gagcagctgc gttccccgcg
    12901 actccggctg gtcgaaccgg gtgttcgtgt cgatggtgat caccacgaac ccgtgcgagg
    12961 cgagccgggg ccccagccag gcgacggcgc tctgcgactc cacgtagccg ggggccacgg
    13021 cgatccccgc gaacgtcccc tggctgtcgt ccgacgggta gtagaccgtg ccgccgccga
    13081 acccgtggcc cgcgggcacc gcggcccggg tgacggcgaa cggcccggcg tcggcggcca
    13141 gcgcgtcggc ggtcggctct ggtccccgct ggtacgggtt ctcgtcggcg aacgcctcgg
    13201 tgccgaccag cgttcccgcc gtgagcaaca cagcggtagc cacacctagc gcgcgctttc
    13261 cgagttgagc ggaaagagac atggcagggc tccccgacgt tgagcgtctc gtgatgttcg
    13321 cccaccgtaa aacactcgga catgccgggg aaatggcgcg gccacaagag ctcacaaagc
    13381 gacaaaccgc agggcagggc ttgtcacgta ggccaaacgg cctagcgtgg tcgcgggccg
    13441 atccggctgg tcaccgccag ccggttgaac gcgttgatca ccgtcaccgc ccagaccagc
    13501 tgcgcgagct ccggctcgga gaactcggcg gcggctgtgg cgtagaccgc gtcgggcacc
    13561 cgggtctcgg ccagcagcgt gatcgcctcg gtcagcgcca gggcggcccg ctcacgtgcg
    13621 gtgaacaggc cgctctcccg ccacacgggc agcgcgtgca gccgccgggt gtcctcgccg
    13681 tgcccggcgg cctcgctggt gtgcaggtcg acgcagaacg cgcagccgtt gagctgcgag
    13741 gcccgcaccc gcaccagcgc gacgagccca gcggccagcc cagcctcgac ggcctggcgc
    13801 tcggcggtga cgtgcaggtc gatcagcttc tggtacagct ccggtgcggc cgacgtcaca
    13861 gccacccgag ggcgggccag gtcggttccc gggccactca tgtccactgc ccggtgccga
    13921 aggtgtcctg gccgctgcgg atcagcgagc gaagctccat ccgccggacc ttgccggtgc
    13981 cggtgcgcgg cacctggtcc caggtcagca cgaccgggtc ggccagggcg ggcaggtcgc
    14041 gcagggcgtc gtgccaggcg tcctggtcga gcaccccgtt cttggtgacc acgaccggga
    14101 ccggcagcct gcccggggtg ccgagcacga cgcactcgac cgcgtcgggc acccggtcct
    14161 ccaagacgtc ctccagttcg acgcagcttt ggccgggcag gacgtcgacc tcccggtcca
    14221 gcagcaggta cgagccgccg cgggtgcgca cgccgacgtc gccggtgttc caccacgggc
    14281 cggacgcctt ggcctgccag cggtcgcgtt cgcccaggta gtccaggcag cggaccctgg
    14341 tgcgggtgag gacgaggccg gggcggccgg tgggcacgtc ctggaacgtg cgcgggtcga
    14401 ccacgcggag ccggacgcgg ccggggacgg gcctgccgag gttgcgggtg gtggggtgcc
    14461 gacggtcgcg ttcggccacc gagcggcggg tgagcagccg gatggtgagc ggcccggtct
    14521 cggtctgccc ccacacctgc acccacaccg gccgccgccg ggtggcggcg aggaacgcgc
    14581 ggaccgtggg cgggtgcatg gcgtcgaacg tgctgacgta gagccggacg tcgtggaacg
    14641 ggttgtcggc gccctcggcc agcggctgcc agcgcacgaa cgtcgagggc agcgcctcca
    14701 gggtggtcgg cgggtgcgcg cgcagggtcg gctcggcctc gtgcggctcc ggctccgcga
    14761 tgaccacgac cttgcgcggc gcgagccaca gcacgctcgc cgtccacggg atcgcccggc
    14821 cgtggcagta cgcgatggcg gagcagaccg tgtcgcgctt gcggctggac acgatcggca
    14881 gccgggtcgc ctcggcggcg gcgataccct ggatcagcgt gcgggtgctg tgcacgacca
    14941 gtttgggcat cccggtggtg ccggaggtgt ggttgacgac cagcggatcg tcggcgtcgc
    15001 ggaaaaccgg cggcggcggc tcgtggccgc gcaggtcggc cagcgggagg gtgcccgggt
    15061 gcggcccgtc gagggtgacg gtgcgccggg cgaacgcggt caggtcggtc tcgttgtcgc
    15121 gggcgtggtc gagcacggtg caggtggtca ccagcagcgc cgggtcgagc cgcttgagca
    15181 ggatttgcgc ggtctccggg gtgaggtggt ccgacagcag cgccgggacc gcgccgatgc
    15241 gggccgcggc gcaggcgagc agcacgtagt cccagtggtt ctccttcacc accgcgaccc
    15301 ggtcgccggg ccgcacgccc gcggcgtgca gccagcccgc ggtggcgcgg accagggcgg
    15361 ccagcgcggg gatgtcgtag cgggtgccgt ggccgggggc gaggtcgagc ggcctgctca
    15421 ggtgcaccac ggtcttggtt ccgcgggcga gcaggtcgtc gaagagcgtg cccaggtcgc
    15481 cgggcttgct tctgcgacgg tccgcggcgg cggtcttcca cactgcttgt tttctgctct
    15541 tcacggctat tggacgtcct tccggccgat gacggtgacc atgacctgcg aaagccaggt
    15601 gtgccggggg tcggccaggt cggcgaccgc cctgtctatg tccatttcgg acacagagga
    15661 ctccttaacc gcggcgagca tcgcgggccg caggtgttcg agccacaggg cgaaccagcg
    15721 gctttccggg gtgccgccgc gcacgacctc ggcgcggccg tcggcgcgca cgtcggacag
    15781 tccggccgcg gtgaccaggt cgacgtcgag caggccgcag cgcgggtggt agccggactc
    15841 gaccatgacc gcgtaggcgg cgcgcttgac ctccgggtgg aacggcccgg cggcgtggct
    15901 gaacagcgac gcggtgtcgg tgtcctccag caccaggtgc ccgcccgggc gcagcgcggc
    15961 gcacagcgcg cgcacggccg ccgcccggtc gccgaggtgc tgcacgacca ggcgggcgtg
    16021 cacgacgtcg taggcggcca ccgggagggc gccggtgcgg acgtccacct ggcacaccgc
    16081 gaccccgagg ccgcgcagcc ggtcgagccg ggaggtgtcg atgtcgaccg cggtcacggc
    16141 cgcgccgcgc tcggccatcc aggcggcgat cgagccgcgg ccggcgccga cctccaggca
    16201 ccgcgagccg gggccgatgc cgagcgtgga cagccgggag atcgttcccg ggtcccacag
    16261 ccgctcgccg aggctgagcc gttcgtcctc gcgctggaac gcggtgccga acacgtactg
    16321 cgcggtgttt cccgcgcttc cgttcgtttc cacggtcgcc gcgattccgg tggccgcgtc
    16381 agccacgggc caccgccgag acgcccgcgg tcctcgggac ggccaggcgt tcggcgacca
    16441 gttccgccga gcggaccgcg gcctcgctgc tcggccgcag cagccaccag tcgccagcgt
    16501 actccacagt ggacggtggg cggcggacga agtcggggcg cgcggccatg gcagcgggcg
    16561 tcggcatcgg caggccgtgc cggaaccggg tgaccacggt cgcgcgcagc gcgtcggcca
    16621 gtccgggaac gtagcgctcg gcctgctcgg tgagggtggc ggcgatctcg ccgtcggtgg
    16681 cggacagcaa ctccgccgac accgagggac cggcgaccag ggtgaccagg ccgcgctctg
    16741 gcggcacccg gccggggtgc ttgcggtcgt cgagcacgat gcccgccagt tccgggttct
    16801 ccaccgtcgg gaccgccagc gcgaacgact gtccgccgcc cgcaggcgcg accggcctgc
    16861 ccagcaggca gatcaccttg atcatcggcc ggaactcgca ggcgcgcacg taatcggggg
    16921 cctgcgcgtg caccgccgct gcgaccgggg caggcacggc gagcaccacc gtgcgggcgt
    16981 tcaccaccgc gccgcctgcg aagacgcggg cgccggaccc ggtggcgacg acctcgtcga
    17041 cggtgacccc ggtgctgatc tcgacgccct cggcgagttt gcgcgccagc acgtccatgc
    17101 cgtcgcggaa ggtgcggaac gtgctggtgg gcccgaccgc gagcaggtgg ctgagcagcg
    17161 ggcccgcgca ggcccgttcg gtgtcccagc cgaagaaccc gccggtcagc ggctggaaca
    17221 ggtagtcgtg caggtcgccg cgggtgacgt cggcgatggc gcggtggccc agcggcgtcg
    17281 cttcgggcgc gtcggtgtcg tattccttgc gccgcagggc cgccaggccc aggagccgga
    17341 ccagggcgag ccgggacacg cgcgacagcg cggcgcccgc cagcaggccg cgcgggtcgc
    17401 cgacgtgcgg gtgggcccgg ccctcccgcc acatcgccag gtccgcgccg atcgccggta
    17461 cctccacttc ggacattccg aactcgcgga tcagccgcca catggccgga tagccgcagg
    17521 agccgatcat ctccgcgccg gtgtcgatca ggtagccgtc gcggcgcagg ctcgccatcc
    17581 ggccgccgac gtgctcggcg gactcgaaga cgtgcaccgc gcggcccgcc gcgcgcagcc
    17641 ggtgggccag ggcgagcccg gccaccccgg cgccgacgac ggcgacatcc aggtcagaac
    17701 tcacggacgt gcccccaggg cgatggtcag gttgatggcg atcagggtgg cgacggtggc
    17761 ccggtgcgcc cacaggccga gcagccgggc gcgcagcagg tcgccgaggc cgacgccgcg
    17821 ccgaagctgc gcgacgcgca ggaagaccgc gggcgccatg gcgatggcga accaccacgg
    17881 cgccgcgccg agtccggccg ccgtgacgat cagggcgatc tcggccaggg tgagcgcgac
    17941 gatgaacgcc ttgttcccct gccgggaaag caggacggcc gcggtcttgc ggccgacggc
    18001 ggcgtcgccg tcggcatcgc gggtgttgga gtagacaccg aacagcagcg gcccgagtcc
    18061 gaaaaggacg gactggacga cggcgaactc cgacggcgcg cccgcggtca gcccgacccc
    18121 gacgagcacc agcccgacgc cgaacccggc gaggaagacc tcctgccagc cgtggtagct
    18181 cagcttcacg ccccaggagt actgcaccgc cgtcaccagg cacagcgcca gcagcccgac
    18241 cgtccacagc gcgctgaacg gcgcgagcac ggccgccagc gcccacagca gcgcgcccgc
    18301 gctcgccgcg gcccagccga agcggatcgc gtccgcctcg gccagttccc cggtgagcag
    18361 cggtttgcgg gcgagtttgc gggccggggc gtccgggccg tagttggccg cgtcgctgcc
    18421 gtcgcggtgc ccggtcacgt cgtcgaaggc gaccgccgcg ctcaccacgc acaccgtgcc
    18481 gacaccgaac gcggcgagcg tgcccagcac cgccggggtg aaccaggccg cggccccggc
    18541 cagcgaccag gccagcggga gcgccaggta gtagtcccac acgtcgagct tggccaggcg
    18601 cgcgtaggcg ccgactctgc cgggcgcggc ggtcagcgac agggtcgcgg tcatcagggt
    18661 cctccgggga aatcgcagac cgcgtcggcg atgtgctcga cctgggcgtc ggtcaggtgc
    18721 ggatacaggg gcagggcgag cgtgcgggcg caggcaagct ccgcgtgcgg ccagtactgc
    18781 ccgggtctgg cgtagggggc gaacgcgggc tgcgctggca gcggcgcggg gtagtagacg
    18841 tggctgccga cgccgcggga agcgaggtgg cgcttgagtt cgtcgcgccg gtcggcgagc
    18901 agggagtaca cgtagaagca gcggccctcg cggccgggcg gcggggcctg cacgccgcgg
    18961 tcgcccagcg cggcgaaccg ctcggtgtag tagtcggcga tctccgcgcg ccgcgccagc
    19021 cgggcggcga ggccgggcag ccggtgcagc tggaagtcgg ccatgatctc gtcgaaccgg
    19081 ctgttgtagc cgaccaggtg gtgcacgaac cggttcttgc cgtcctggcc gtggttgcgc
    19141 agcatccgcg ccaggcggcc gatttccggg tcgtcggtga cgaccgcgcc gccctcgccg
    19201 atcgagccga acgtcttgac ctgcacgaag gagaacaccc ctgcctcgcc ccagcggcct
    19261 gcctgcaatc cgcgcagcac cccgccctgg gccacggccg agtcctcgat cagccgcaca
    19321 tcgtggcggc gggcgagttc gcgcatggtg ggcatgtcgg ccatcaccga gaacatgtgc
    19381 gcgggcatga tcgccgccgt gcgcgcggtg atcgccgcct cgacctcgta gggctcgacc
    19441 accatcgtcc acgggtgcac gtcgacgaaa accgggacgg cgccgacgtt gaccaccgac
    19501 gcggccagcg gcgcgcagcc gaaggcgggc accacgacct cgtcgcccgg cccgatgtcc
    19561 atcgcgcgca gcaccagcat cagcgcggcg gtgccgctgc cgcaggccac cacgtccgcg
    19621 gccccggtgt tcacccgcag cgcctcctcg aacgccgcgg tgcgctcgcc gaggatgaac
    19681 cgctggtcgt cggcgaggcc gaccctgcgg acggtctcca gcaccacgtc gcgctcgccg
    19741 tcgaacaggt cgggcgggaa gaacggcagc cggggcatgg acgcggtcac gaccggctcc
    19801 cgccgtagaa cgctctgatc aactcgcaca cccggtcgac ctgcgcttcg gtgaggtccg
    19861 ggtagagcgg cagggcgacg gtgcgcgcgc aggccgcctc ggcgtgcggg aactccccgg
    19921 gccggtggcc cagatcggcg aagcacggct gccggtgcag cgggaccggg tagtaggtct
    19981 cggtgcccac gtggtgggcg gcgagatagg cgactaacga gtcgcggtgc tccacttcga
    20041 cggcgtagac gtagaacacc gggttcgtct cggcctcgcg ctcgaccacg gtcggcagcc
    20101 tgcgcacccc tggacagccg cgcaggcgct cggtgtaggc gccagccagc gccgcacggc
    20161 gggcgatgtc ggcgtcgagc ctgcccagct tggccagcag cacggcggcc tggacgtcgt
    20221 ccatcttgct gttcaggccc gggagcacgg tctcgttgcc gatgccgggg aagtggtcga
    20281 gggtgtgccc gaaccggccg tggtggcgca gcgcggccgc ggtctcggcg atccggtcgt
    20341 cgttggtgat gaccgcgccc gcgtcgccga gcgcgccgag ggtcttggtc gggaagaacg
    20401 acagcacccc gcccgcgccg tgcaggcccg cgtgcgtgcc gtcccagcgc atcccgatgg
    20461 cctccgcgct gtcctcgacc acggtcagcg cgtgccgctc ggcgagcctg gtgacggccc
    20521 cgaggtcggc gagctggcag aacaggtgca ccggcatgag catccgggtg cgcgcggtga
    20581 ccgcggccgc ggcggcggca gggtcgagcg cgtaggtgac cgggtcgatg tcggcgaaca
    20641 ccggccgccc gcccgcgagc accaccgagg acgccgaggc cacgaagctg aacgcgggca
    20701 cgaccacctc gtcgcccgcc tccaggcccg ccgcgcgcag cagcagcacc agcgcgtcgg
    20761 tgccggagtt gaccccgacg acgtgcgcgg cgtcgacgac ccggccaagc gcggcctcga
    20821 actcgccgac cgcgtggccg tgggagtact tgccgcgttc gacgacggcg gcgacattcg
    20881 cctcgatctc gggccacagc gcggcgaagg tggccgcctg ggtgaaaaac ggcacccgcg
    20941 caccggatgg ggtggccgtg ccgggctccg cgagcgtcgc ggcgtgctcc atgcctgtcc
    21001 tttcaccgac ggtgaccgtg cgccgacggc cgccatctgc ggcc
//
