LOCUS       NZ_FMZK01000024        27276 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Streptomyces prasinopilosus strain CGMCC 4.3504, whole genome
            shotgun sequence.
ACCESSION   NZ_FMZK01000024
VERSION     NZ_FMZK01000024.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces prasinopilosus
  ORGANISM  Streptomyces prasinopilosus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900101585.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 02:19:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,269
            CDSs (total)                      :: 6,190
            Genes (coding)                    :: 5,988
            CDSs (with protein)               :: 5,988
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 202
            CDSs (without protein)            :: 202
            Pseudo Genes (ambiguous residues) :: 0 of 202
            Pseudo Genes (frameshifted)       :: 63 of 202
            Pseudo Genes (incomplete)         :: 175 of 202
            Pseudo Genes (internal stop)      :: 8 of 202
            Pseudo Genes (multiple problems)  :: 40 of 202
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:44:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6732
            Orig. end                         :: 34008
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMZK01000024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27276
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..27276
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27276
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21086](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    815..831
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     gene            1547..2560
                     /locus_tag="BLS36_RS31245"
                     /old_locus_tag="SAMN05216505_1249"
     CDS             1547..2560
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381063.1"
                     /locus_tag="BLS36_RS31245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_1249"
                     /product="AAA family ATPase"
                     /protein_id="WP_055571910.1"
                     /transl_table=11
                     /translation="MNWTPYYTGTGSIPEQPQRLPPPPPWRAPTKKTRGAADAAQSPSP
                     ASTYRADPGLIDAVNAALHLRRPLLLTGPAGSGKSSVIEQIAAELGLGSVLRWHITSRS
                     TLADALYRYDALGRIHAYNLRAVGRPAASRNGRVARLAARATRDDIGDFVQLGPLGTAL
                     LPGNSPRALLIDEIDKSDLDLPSDLLDVLERGRFEISELARHSRSRVTVRTADPGTRHD
                     IDNGLVECEEFPVIVLTSNGERDFPAPFLRRCVRFDTPALTVSTLTSIVEAHLERVEED
                     TTHTLVNAFVDRLNRGENLAVDQLLSAVHLLRGNRIQDDQQRTRLQELLLQGLGRG"
     gene            2553..6938
                     /locus_tag="BLS36_RS31250"
                     /old_locus_tag="SAMN05216505_12410"
     CDS             2553..6938
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041121.1"
                     /locus_tag="BLS36_RS31250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12410"
                     /product="SAV_2336 N-terminal domain-related protein"
                     /protein_id="WP_055571911.1"
                     /transl_table=11
                     /translation="MAENRAARLLAALAHADLGDLSGSAEGDIRETLDALLLAAARSGT
                     SQIGDIPTNPLPATEEAPADAPLQPEPGTDDSCDEPSAPESGSDANALGTASVWLKDDS
                     SSHSIPGRPLSIGRAPALPNALDIGRALRPLRRFRPSRVHRRLDLGATVDHYTRTGVLV
                     PQLAPAAEPWLEVVLVVDRGTSMAVWDETSLALTKVLRTLSAFRSVHVWHLEHPPEAPP
                     VLRNHHGRPLLMDPSDPRHVQPAHRLVLVVSDCAAPAWRRNDLWQTLHTWGRTAPVALI
                     NPLPKRLWQRSGLDLPRTTATASVPASPGRLLAYRRPRPFRDDAPGTRPWQALPVLQVD
                     AHQILTWARAMMRTDPSGCEAVLVPASGRVPSRNRSPRPSAAPPGAPATDTQVAAAAEA
                     FTDNLHSPAVRLAIAASSLDVFTLPLLDVLRERIVPEAALADTAEFLTAGLLTATRHED
                     ADIVYRFHPAAADHLRGLLSRDQAWDTHFALTDHLAAHPQAPHGIVAALHSLTSQENLP
                     AGLRPVAQAAAATARLLGLESTEPRSGPDEQARLAAECPDDEKDDAQQTPDPAVPDEPP
                     EPVPDMDAAPVDGAVRLHAHQRDMLDRLNAEREIHDRHRNLLIAPPGTGKTLMAAFDYK
                     HLCEQHQQDLRLLFIADSLATLEQARWTYQEILMTANFGERLHGGAGTPQLGSHVFDTW
                     QSLRRVMDELPSDHFDVIVIDEIHRIGSPTVVRILEHFTPKELLSLSSVTPERADSLSI
                     HDTFFDGRIAAEMRLPDALASGLLPSLHYFGIADGTDLRRLDWKQGTYDRASLNALLTA
                     DHARAQLVIRAIRDTVPDVKTMRAVGFCQSVAHAELMTQCFRDAGFRAVALTAADRPAT
                     RQETFSSLRDGNLQVIFCVDALSESVHIPEVDTLLLLRPTSSTLQFLRQLGVGLPRFPG
                     KPVLTVLDFIGHHRKEFRLDYQFRAMTNLAGRQLLHHLEHDFHQLPTGSMITFDQEAKS
                     IVLDSLWEQMRGGVTDTADGSRPVGEGQHERSAAPTADLVTDTEPASGPAATDRLRAFD
                     QSPRVVMMKGGNETGTNSAVGIMLTPRLVLTCASMLDPSARMWIVRADGTEIACRTVWK
                     RPGALEATLVLAEENILESEEWERLLPSRLRWGRMPNRVMSPVRITGFRRSGKRIELNG
                     QARPTAAQIAVEVTSSVTEGELAGLPGALVSCNGFFVGMVTRRHLQRPQLVAVPAALLL
                     QDQGFHRALATHMTTPYELEDVGIEPSSDSWDGPLAVCLAIEAHIVSGRRGSDAHHRES
                     ALAHEIRESLVAIMHRVGIVGVVVEEAVADARADLLMRLDGPAAIQDMGRVLAELQTAV
                     ATHHDVAFGVAASIGEVTDTRLGLAGGAVSEAVRLGSNSFFREQLHQAARFVDSPVYFA
                     VSNTLRARIAGMLGPAWEGRFVSLEPHSQPAPEAGWMYEGPTEQLGGALAAIRHGGLLP
                     "
     gene            6962..7897
                     /locus_tag="BLS36_RS31255"
                     /old_locus_tag="SAMN05216505_12411"
     CDS             6962..7897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984061.1"
                     /locus_tag="BLS36_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12411"
                     /product="hypothetical protein"
                     /protein_id="WP_055571912.1"
                     /transl_table=11
                     /translation="MDTKNKARADAEKKVGDFRRVDSERVALEIAPALAAVRTLDLEVF
                     RAGLRGADNQRYLALQRTDPQGQVVLGLVLARNADIHLPATLGLHVDRVVGDDDGYRVM
                     PSWLTYDRLPTVVRANKRSPGSRNGTSEASHDAYRDTVGGHLVIETLLDAFAFFGRCDP
                     TLARRAPGTDNLAHFPLPAMNTGDGYDYERRHPDQPNRADFGAEARRLTEDVPPSGSGR
                     EISYRLDSDGTAVYCRHTVERFGLRSAFTESAAQIVRDIRAGYTYVAVATDGVHHPVTV
                     DADGCPWADGVVLEDYPFPSPTGIRSPRHG"
     misc_feature    8278..8289
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            8822..10390
                     /locus_tag="BLS36_RS31265"
                     /old_locus_tag="SAMN05216505_12412"
     CDS             8822..10390
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLS36_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05216505_12412"
                     /product="hypothetical protein"
                     /protein_id="WP_218135284.1"
                     /transl_table=11
                     /translation="MAFQAACVCTRSSRKSITPIPALDRLLELRVTSDAPDSGLAAGVR
                     LAVVAPDHGAAMGVLAGDLPGENVAVDVGVDDGEAQAPWFERSGWTGFVSRVRDHVGMG
                     DNKRRQRNTYEVLGLQPLFNAFGTSVLATGVFDSITKRYGNSTGSLFMARSGVYGSVLK
                     QYGRGIGALSFLEPQRSISVGVLDSVKTGSLLGESFFGSHKTAALGLDAFRGSGSVGAW
                     GADPFGWGKGAVTTGVYGGVLKAAGPDQLSGSFFPTARGAAASVWLPGLLDSFTAPLAP
                     SLPRRAEELADLLLPPNLQGFSSSEWSQLIDITTDAGIGLMWAPGAGHLRALLAEDSRE
                     GRYAYLLQHQDELLDELSAGMQEVTEEPLQDLVRLGMRVIECARAGLWEGALALATNVL
                     YSAMEEHGIEWYRREFRSVRDHNNQPIRGINGPGPTVEFVLSNVPMPERRVGIFDLRTH
                     LVTRPMSHVFKNSALVQGQHNRHAVCHEASYTSLREVYVLPAMLNMHALLRVLDEKMSD
                     DSPSP"
     misc_feature    8888..8890
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8906..8908
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<11109..>11672)
                     /locus_tag="BLS36_RS31270"
                     /pseudo=""
     CDS             complement(<11109..11672)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385677.1"
                     /locus_tag="BLS36_RS31270"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWSYDAIGNETAGASTDDYARTAEKWTGHSQMSSITVAGKTYAGQ
                     YGSTDQSERIKLGDTFFHNGPLGLSAKTTAGVDMGFNREPGGTLNSMTTGGKTYYYLTD
                     AIGSVVALADGDGNKVNTYAYSPRGVRILARSSEPVAQPYRFAGGYQDPTGLYHFQARY
                     YDANIGRFTQPDPSGQEKNPYLYAE"
     gene            complement(11837..12760)
                     /locus_tag="BLS36_RS31275"
                     /old_locus_tag="SAMN05216505_12414"
     CDS             complement(11837..12760)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006136279.1"
                     /locus_tag="BLS36_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12414"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_079039721.1"
                     /transl_table=11
                     /translation="MLALLVALPLVAGGRLPDRLATHWDAGSGKPDSSMPLWAASLFPA
                     LIWGVAAALVALVWWRARVTSSGGVGGWVGATLGSGGVMLVGGQASIVRANLDHADWRE
                     ADSVTVSVVVTLVAAVGVGAAALLASRRTPAAVPTGGGPTMEIPAGERFVWLSRTSNPW
                     LHATAAVTGVVAVAAVVAGLGGLMGAEAALLAGPFALASVLVLGFASVQARVSERGLEV
                     AFGPLGWPARRWAADDIASARVETRTPSQVGGWGYRLSGLGTTVMLRSGECLVTHTHNG
                     KNFAVSVDDAERGAALLNSLNAQRSS"
     gene            complement(12820..13167)
                     /locus_tag="BLS36_RS31280"
     CDS             complement(12820..13167)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673841.1"
                     /locus_tag="BLS36_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_055571916.1"
                     /transl_table=11
                     /translation="MLLRLNTADNRPLHEQVAGAIRRAIAEGECEPGDRLPPARDLSQV
                     LGINVNTVLRGLRALRDEGVLEFRRGRGVTVAHGAAERSALLDRVRDVVADAARLGYSR
                     NDLIDMIRGIS"
     gene            13440..14222
                     /locus_tag="BLS36_RS31285"
                     /old_locus_tag="SAMN05216505_12415"
     CDS             13440..14222
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (11-245). E-value:
                     4.5e-28. Score: 90.4. Matches aSDomain:
                     nrpspksdomains_BLS36_RS31285_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449132.1"
                     /locus_tag="BLS36_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12415"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_055571927.1"
                     /sec_met_domain="PF00561 (E-value: 4.8e-18, bitscore: 56.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.8e-19, bitscore:
                     59.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRWRMLGSGDPVVLVHGTPYSSFLWRDIAPALARTRTVFVFDHL
                     GFGRSDQGEAQDLSLAAHARNFARLLDHWGLSRPSVVAHDIGGAVALRTLLLEERSYRD
                     LTLFDAVSGGQWERGLFRLILEHPGVFQQLPDYAHEALVASHLRHATHVGLRPGVLEAF
                     LAPWRGAAGQAAFYRQYSQIKQADTAAYEHLLGGMSLPVRIIWGREDRILPAEYAEWLH
                     EHIPHAELHWIEDAGHLLQEDAPGQLTTYLTAPFPSDK"
     aSDomain        13473..14174
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS36_RS31285_Abhydrolase_1.1"
                     /evalue="4.50E-28"
                     /label="BLS36_RS31285_Abhydrolase_1.1"
                     /locus_tag="BLS36_RS31285"
                     /protein_end="245"
                     /protein_start="11"
                     /score="90.4"
                     /tool="antismash"
                     /translation="PVVLVHGTPYSSFLWRDIAPALARTRTVFVFDHLGFGRSDQGEAQ
                     DLSLAAHARNFARLLDHWGLSRPSVVAHDIGGAVALRTLLLEERSYRDLTLFDAVSGGQ
                     WERGLFRLILEHPGVFQQLPDYAHEALVASHLRHATHVGLRPGVLEAFLAPWRGAAGQA
                     AFYRQYSQIKQADTAAYEHLLGGMSLPVRIIWGREDRILPAEYAEWLHEHIPHAELHWI
                     EDAGHLLQEDAP"
     gene            <14227..>15348
                     /locus_tag="BLS36_RS31290"
                     /old_locus_tag="SAMN05216505_12416"
                     /pseudo=""
     CDS             14227..>15348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677576.1"
                     /locus_tag="BLS36_RS31290"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SAMN05216505_12416"
                     /product="helicase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQPPDRVWSAWLCGDHLVSERREVLRQFANGVDAAGRRVHRAFLA
                     GCRVLGEGVDITGERGVEAVCFADTRGSQVEIVQNIGRALRLNEDGSTKVARIIVPVFL
                     EPGEDPADMVASASFRPLAAVLQGLRSHGERLVEQLASRALTGGKRKVRVRRGAEGRIV
                     RVGGEGDGEGQEDDVQAVEAALLHFSSPRDAATIAAFLRARVYRPESLVWPEGYRALLR
                     WRGENKITGLYAVPYDTEVEVGVTQDFPLGRGVRHQRKALRAGEPEDRRKTLLDVPEAG
                     MVWEPGEEAWEAKLAAPRSCRRAMGHLAPRQDAVWGEGGTMVPIGRHMANLRRKGGLGK
                     DPKRAKARAQQLAAIDPDWNCAWLLDWQRHYRVL"
     gene            complement(15533..16702)
                     /locus_tag="BLS36_RS31295"
                     /old_locus_tag="SAMN05216505_12417"
     CDS             complement(15533..16702)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019474.4"
                     /locus_tag="BLS36_RS31295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12417"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_244904986.1"
                     /transl_table=11
                     /translation="MPLDPQIETLLQRVAAEGGPAPETLTVAQNRAFGRAFGALAGAPV
                     PVADVRDTAAAADGRTVPVRLYRPVTEPNAGPLPVTLFLHGGGWVFGDLDTQDNIARTV
                     AVRSRTIVVSVDYRLAPEHRFPAAVDDAYAALTWVADSAAGFGGDGKRIAVFGESAGGN
                     LAAVLAQESLRRGGPRITLQVLAYPAVDRFDDSPSMYENMAGPVLSRSYLEWFWGAYLS
                     TPDQGADPRVSPARSDELAGLAPAVIATAENDPLRDQGDHYARKLAGAGVPVQHLPIEG
                     AVHGFLSFTGSVQLSRDVLNRLADAVATAFHRPGPRDAVSRRTPAARGQDSDHHRAEKP
                     YLNRPRNIQAEQVPHPGDLPATGTRRQDPPAARRCEPNRAAPEDPALSD"
     misc_feature    complement(16777..16791)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.64"
                     /tool="antismash"
     misc_feature    16778..16792
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     gene            16812..17447
                     /locus_tag="BLS36_RS31300"
                     /old_locus_tag="SAMN05216505_12418"
     CDS             16812..17447
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004993651.1"
                     /locus_tag="BLS36_RS31300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12418"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055571917.1"
                     /transl_table=11
                     /translation="MSAPGKAGEPKEQRLTEGGRRTRERIIETAAELMFHRGAGGTSIP
                     DIQAAAGVSASQIYHYFGDKQGLVLAVIDHQTDAQLARQRPLLDSLDSIEALRAWCDTA
                     GSRQDARGCEGGCEIGSLAGELADSDQSARARLVSAFDRWEEPIRSGLARMQARGELSE
                     HADTAALATALLAAVQGGMLLSQVRRSSTAYRQAVSAVIDHIESHLVR"
     gene            17636..18103
                     /locus_tag="BLS36_RS31305"
                     /old_locus_tag="SAMN05216505_12419"
     CDS             17636..18103
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823149.1"
                     /locus_tag="BLS36_RS31305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12419"
                     /product="VOC family protein"
                     /protein_id="WP_055571918.1"
                     /transl_table=11
                     /translation="MTHDASRIRLVQTVLDSTDARELAEFYRSLLGLDYAEGDEPPPAG
                     QPDEHGGDWLVLRNPDGGPQLAFQQVERLREPDWPDGPVPQQMHLDLSVASLEELRNQH
                     ERVLALGGSLLSDRDRPDPDDEERFRVYRDPEGHPFCIFVAERDEQPAGAP"
     gene            complement(18446..19474)
                     /locus_tag="BLS36_RS31310"
                     /old_locus_tag="SAMN05216505_12420"
     CDS             complement(18446..19474)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823103.1"
                     /locus_tag="BLS36_RS31310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12420"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_055571919.1"
                     /transl_table=11
                     /translation="MDLLVVGGGPAGLATALHAARAGLEAVVWEQRAGTLDKACGEGLM
                     PGAVAELTALGVHPPGYDLRGIRYVAGAHRADAAFRAGPGRGVRRTVLHAALREAVLAA
                     GVRVEQRTVRRVEQDEDGVVADGTRARHLVAADGLHSPIRRALGLHRPRRAPRRHGLRR
                     HYVLAPWSDHVEVHWARDAEAYVTPVSDNLVGVAVLTAGRGPYDGHLAAFPELRERLAG
                     AESATPVRGAGPLRQDASARTAGRVLLVGDAAGYVDALTGEGIALALAQAPAAVRAVVD
                     GDPAAYEREWRRLTRRYRRLTRALLGATRVPPLRAALVPAAQRLPRLFSAAVDALARPP
                     GT"
     gene            complement(19486..20004)
                     /locus_tag="BLS36_RS31315"
                     /old_locus_tag="SAMN05216505_12421"
     CDS             complement(19486..20004)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004671 - protein C-terminal
                     S-isoprenylcysteine carboxyl O-methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006481 - C-terminal protein methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000155: Methylation (73% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150: isoprenylcysteine carboxyl methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823104.1"
                     /locus_tag="BLS36_RS31315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12421"
                     /product="isoprenylcysteine carboxylmethyltransferase
                     family protein"
                     /protein_id="WP_055571920.1"
                     /transl_table=11
                     /translation="MIGQVLFTVLVSAVALERVAELAVSRRNTHWSLARGGVESGRGHY
                     PFMVVLHTGLLVGALVEVWVRRPDAVWVLAWTMLALVAAAQALRWWCIATLGRQWNTRV
                     IIVPGAPRVTGGPYRRLSHPNYVAVAVEGLALPLVHSAWVTALVFTVLNGFLLATRIRT
                     EDTALARPA"
     gene            complement(20001..21086)
                     /locus_tag="BLS36_RS31320"
                     /old_locus_tag="SAMN05216505_12422"
     CDS             complement(20001..21086)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010044909.1"
                     /locus_tag="BLS36_RS31320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12422"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_055571921.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2.8e-22,
                     bitscore: 70.0, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 2.4e-17,
                     bitscore: 54.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMRVLSVRGVLPEHRHRQEEITESFATTLVEGTLERGVVERFHR
                     NVCVETRHSVLPLESYARLGDFGRANDVFIRAGVELGGRAVVDALKDAGLTPSDVDYIV
                     SCTVTGLAVPTLEARVAAQIGLRPDVVRLPLVGLGCVAGAAGIARLHDLLRGRPDGVAV
                     LMSVELCSLTLQREDTSLANLVASGLFGDGAAAVVAVGAEHPLARFEHPARPEVLASRS
                     RLYPDTERTMGWDVGPGGFRIVLDSSIPDLVRRYVGDDVRGFLADHHLSDDDLGWYVAH
                     PGGPKVLEALQEALEVERDALAVTWDSLRRIGNLSSASVLHVLADTLADRPPPPGSHGL
                     MLAMGPGFCCELVLLRAPGER"
     gene            complement(21083..22264)
                     /locus_tag="BLS36_RS31325"
                     /old_locus_tag="SAMN05216505_12423"
     CDS             complement(21083..22264)
                     /GO_function="GO:0045550 - geranylgeranyl reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015995 - chlorophyll biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0030494 - bacteriochlorophyll biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474029.1"
                     /locus_tag="BLS36_RS31325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12423"
                     /product="geranylgeranyl reductase family protein"
                     /protein_id="WP_055571922.1"
                     /transl_table=11
                     /translation="MAPAPAHWDLAVVGAGPAGAATALGALRAAPELRVALLDRAVFPR
                     DKACGDGVAPHVLDLLAGVGVTGLLDDRVPVGRLRLGRGGLAAERPMARPVWVVPRRVL
                     DARLVDAAVAAGAHLLCHRVRDLRQRAGAVVLDGELSAAVVVGADGAHSVVRRALGRPR
                     GPMALALRGYAPVGSGRRGVQVIEFGTRHQPSYAWSFDRGDGLANVGYGEFLHQDRPTP
                     TRAHLLERLEALLPGATEGGRHWAGHHLPLSTARRRLPTGRVLLVGDAACLVNPLTGEG
                     IHYAVATGIAAGRAAAAALRDGRPEQAGQRYARATRPILLPHLRHTALAARLARSAHVL
                     EAGLRASAADQRVFDDFVELGLARGRLTPAVALGLGRAFVACLRPSGRPQEPA"
     gene            complement(22264..23100)
                     /locus_tag="BLS36_RS31330"
                     /old_locus_tag="SAMN05216505_12424"
     CDS             complement(22264..23100)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978795.1"
                     /locus_tag="BLS36_RS31330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12424"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_055571923.1"
                     /sec_met_domain="ubiA (E-value: 9.2e-37, bitscore: 117.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGAAPARSGPRPVLALLAAAHGGPALAVGVIAGLLALRSGLRP
                     LDAAVLTGAVLAGQLTIGWGNDLRDLSRDRAAGRTDKPLATGALPVAWAVRALGAAALA
                     CLVLSALTGWRSALVNVLLGAGAGHAYNLGLKATWWSWLPYASAFGTLPSLVTLAGPAP
                     AWAPLWTTGAGAALGVGAHLLDTLPDLADDERTGVRGLPHRIGERSSRVLAVALLSAAS
                     LLAVFAPAGPPSAGGRAALVLVAVLAVFALTGRGRVPFRAALAIALLDVVLLVAAG"
     gene            complement(23097..24161)
                     /locus_tag="BLS36_RS31335"
                     /old_locus_tag="SAMN05216505_12425"
     CDS             complement(23097..24161)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (63-221). E-value:
                     3.3e-10. Score: 31.4. Matches aSDomain:
                     nrpspksdomains_BLS36_RS31335_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978798.1"
                     /locus_tag="BLS36_RS31335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05216505_12425"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_055571924.1"
                     /transl_table=11
                     /translation="MRIVVTGATGNIGSVVVRRLRAEGTHDLVGLARRLPEGPGSRGVD
                     WRSADLSTEACHDTLVEAFTGADAIVHLAWGFQPSHDPAYLARLGIGGTRRVLRAVTQT
                     GVPHLVHMSSIGAYSPKKDDRPVDESWPTGGVRSSRYSRHKAAAERLLDRHETSGAGTL
                     VTRLRPGIVGQRAAGSALLRYGVPAPVPPRVLDLLPILPMDRRLTFEMVHTDDVAEAIV
                     AALHRRAGGPFNLAADTPVTAAVVADALDARLVHVPFAVVRAAVSAAWHAHLQQVDTGW
                     LDMGFALPTLDTTRARTELGWAPTRDGPQVLAEVIEGMRQAASGRTPVLRPRTVLGALG
                     DAVRHGPVAVRRRP"
     aSDomain        complement(23499..23972)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLS36_RS31335_NAD_binding_4.1"
                     /evalue="3.30E-10"
                     /label="BLS36_RS31335_NAD_binding_4.1"
                     /locus_tag="BLS36_RS31335"
                     /protein_end="221"
                     /protein_start="63"
                     /score="31.4"
                     /tool="antismash"
                     /translation="FTGADAIVHLAWGFQPSHDPAYLARLGIGGTRRVLRAVTQTGVPH
                     LVHMSSIGAYSPKKDDRPVDESWPTGGVRSSRYSRHKAAAERLLDRHETSGAGTLVTRL
                     RPGIVGQRAAGSALLRYGVPAPVPPRVLDLLPILPMDRRLTFEMVHTDDVAEAI"
     misc_feature    24962..24977
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    26527..26541
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
ORIGIN
        1 acatgaacct gagtgtccaa cttgccgagc tgctggagga cggggtggcg aatgcagggg
       61 agttcttggc cgtcgacgaa cagttgatca aggagctgcg cagtcgtatc cacactcagg
      121 agccaggcag ttccgtgttc aacggcgttc ctgtgcccgg tgaatcgctg tggctggcct
      181 acaacgtccg ggccgccgtg caacgctcca cgggttctct cggttccgtg gcctgcgaga
      241 ggttacacaa gctgctgggt ccgctggagg gcacggaagg tatcaacagc aggaaacggc
      301 tcgcagactg gctcggcggg ctgggtgagg agcgtcttgg ccaccctgcc gtgcggcgtg
      361 tcctggagtt cgagcgcgat ctgggcatct gcgcttccgc cgtcgccgtc cttgaggaga
      421 ccttcggggg cgctctgacc gacgatttgc tccgcaaggc ggcggcacgc gccggattcc
      481 cgctggaggt ggtggtccgg gttccctgcc tttctctgcg tgacctggtg gagtatgcgg
      541 tccttcacca atcggccgtc gccaccgcgg gacagcaccg gacgttggtg catttcgtcg
      601 ccgcccttgc ccacctgatc agtccaccag atgttcttcc gcggcaactg acagcctggg
      661 cggccacatc gggtgccacc accgctctga acagtcggtt gaaagaactg agcggggcga
      721 caccccgcct ggtcctggtg gccgccgacg acggcggtga gaacgtcgtc cgtgtggagg
      781 catcgcttct cttcggttcg gccgtggtgc acaccgcaca gttcccctgc gagcccgggt
      841 tgagtgccct ggcggcggca ctggatggtg cccgcgagtg ggcgctgtcc tggctgacgg
      901 cagcgggtga gcgactggtg tcggtcgatg tgtcggtccc gacctttctg cttctggatt
      961 ctccgccaga tgaatggcga gtggtccgcg gccgacgcat gctgggcgtc gactatgacg
     1021 tcacgacccg ctggtcgggt ctgctgacgc ccccgcccgg tgtcagcctc gacgacatgc
     1081 tgcacgtcgg cagccagttg ctgtcctcct tgcggaccaa ggatcaagcc ggcccgtcat
     1141 ggctcgactc cgatgatctc agcagcgttg aggcgctttt ggatgtgctc ggccgtcgtc
     1201 gtatgggcgg ctgcgtgtgg ggagtgagcg ccctgccgga gaaggacttc gccctcatgc
     1261 tggaggaact cctcatccac accccggcct tgatctggcc tcggcgtggg agtgtccccg
     1321 acacgcgggc gctccatgat gcggtcgcgg agcactggga gtcgctgccg gagaaactcg
     1381 tccgcgcctt ccagcagcgg ctggagagca gcctgggcga agacgttccc ggtcatctgg
     1441 ctgatatccg tacgacatgg cacgacgcgc actggcagga cttctgtcaa cggcgcgccg
     1501 gccgggcggt catcgcccca caagacgtga cgccgaagga gcaagcatga actggacccc
     1561 gtactacacg ggcacgggaa gcatccccga gcagcctcag aggcttcctc ctccacctcc
     1621 gtggcgcgcg ccgacgaaga agacccgcgg tgcggccgac gcagcgcagt cgccttcccc
     1681 ggcgagcacc taccgggcgg accccggatt gatcgacgcg gttaacgccg cactgcatct
     1741 gcgtcggccc ctgctgctga ccgggccggc tggctccggg aagtcctccg tcatcgagca
     1801 gatcgccgcc gaactcggac tcgggagtgt gctgcgctgg cacatcacct cccgcagcac
     1861 cctcgccgac gcgctctacc gctacgacgc cctgggccgc atccacgcct acaacctccg
     1921 cgccgtcggc cgtcccgccg cctccaggaa tgggcgggtc gcgcgcctcg ccgcccgtgc
     1981 cacacgcgac gacatcgggg acttcgtcca actcggtcct ctcggaactg ccttgctgcc
     2041 cggcaactcc ccccgcgccc tgctgatcga cgagatcgac aagagcgatc tcgacctgcc
     2101 gagcgacctc ctcgacgttc tggaacgtgg tcgcttcgag atttccgaac ttgcccggca
     2161 ttcgaggagc cgggtcaccg tccgcaccgc cgatcccggc acccggcatg acatcgacaa
     2221 cgggctggtg gagtgcgagg agtttccggt catcgtcctc accagcaacg gcgaacgcga
     2281 cttccccgcc ccctttctcc ggcgctgtgt gcggttcgac acgcccgcac tcacggtctc
     2341 gaccctcact agcatcgtcg aggctcactt ggagagggtc gaggaagaca ccacccatac
     2401 cctggtgaac gctttcgtgg accggctgaa ccgcggtgag aacctcgctg tagaccagtt
     2461 gctgagcgcc gtacatctcc tgcggggcaa ccgcatccag gacgaccagc agcggacgcg
     2521 gttgcaggag ctgctgctcc aagggctcgg gcgtggctga gaaccgggcc gcacggttgc
     2581 tggccgccct ggcccatgcc gacctgggcg acctcagcgg cagcgcggag ggggacatcc
     2641 gggagaccct cgacgctctt cttctcgccg ctgccagatc cggcaccagc caaattggtg
     2701 acatccccac caatccgctt ccggccaccg aagaggcacc cgccgacgcg ccccttcagc
     2761 ccgaacctgg aaccgacgac tcctgcgatg agccgtcggc gcctgaatca ggttcggatg
     2821 caaacgctct cgggaccgcc tcggtctggc tgaaggacga cagcagcagc cactcgatcc
     2881 ccggcaggcc tctgagcatc ggccgcgccc cggccctgcc gaacgctctg gacatcggcc
     2941 gtgccctgcg cccgctgcgc cgctttcggc cgtcccgggt tcaccggcgt ctcgacctgg
     3001 gcgccaccgt cgatcactac acccgcaccg gtgtgctcgt cccccagctc gcgcctgccg
     3061 cggagccctg gctggaggtc gtcctggtcg tggaccgcgg cacctccatg gccgtctggg
     3121 acgagacctc actcgccctc accaaggtgc tgcgcaccct gtccgccttc cgcagcgtcc
     3181 acgtatggca tctcgagcat ccgccggagg ccccaccggt actccgcaac caccacggcc
     3241 ggcccctcct catggacccg tccgaccccc gacatgtcca gccggcccac cggctcgtgc
     3301 tcgtcgtttc cgactgcgcg gcccccgcct ggcgccgaaa cgacctgtgg cagacgctcc
     3361 acacgtgggg acggacggct cccgtggcct tgatcaaccc gcttcccaaa cgcctctggc
     3421 aacgctccgg cctcgacctg ccccggacca ccgcaaccgc ctccgtcccg gcatcccccg
     3481 gacggctcct cgcctaccgc cgtccccgcc ccttccgcga cgacgcccca gggacgcggc
     3541 cctggcaggc attgcccgtg ctgcaagtgg atgctcacca gatcctcacc tgggcgcgcg
     3601 ccatgatgcg caccgacccg agcggctgcg aggccgtcct cgtcccggct tcagggcgcg
     3661 taccctccag aaaccgcagt ccgcgaccga gtgccgcccc acccggtgcg ccggcgaccg
     3721 acacacaggt cgcagccgcg gcagaagcct tcacggacaa cctgcactcc cccgccgtcc
     3781 gactggcgat cgccgcctcg tcgctcgacg tgttcaccct ccccctgctc gacgtgctcc
     3841 gtgagcgcat cgtccccgaa gccgccctgg ccgacaccgc ggagttcctc accgccgggc
     3901 tgctcacagc gacccggcac gaggacgcag acatcgtgta ccgattccac ccggctgcgg
     3961 cggaccatct gcgcgggctg ctgagccgcg accaggcgtg ggacacccac tttgccctca
     4021 ccgaccatct cgcagcccat cctcaggccc cgcacggaat cgtcgccgca ctgcactcgc
     4081 tcaccagcca ggagaacctg cccgccgggc tccggcccgt cgcccaagcg gctgcggcaa
     4141 cggcgcgtct tctcgggctt gagtccaccg agcctcgctc cggccccgac gagcaggccc
     4201 gcctcgcggc tgagtgcccc gacgacgaga aggacgatgc tcagcagact cctgacccag
     4261 ctgtgccaga cgagccccca gagccggtgc cggacatgga cgccgccccg gtcgacgggg
     4321 cggtcaggtt gcatgctcac cagcgcgaca tgctcgatcg tctgaacgcc gagcgcgaga
     4381 tccacgaccg gcaccgtaac ctcctcattg ctccccccgg caccggcaaa actctcatgg
     4441 ccgccttcga ctacaaacac ctgtgcgagc agcaccagca agacctgcgc cttctcttca
     4501 tcgcggacag cctggcaacg ctggagcagg cacgctggac ctaccaggaa atcctcatga
     4561 ccgcaaactt cggagagcgc ctgcatggcg gcgcagggac tccgcagctt gggagccacg
     4621 tgttcgacac gtggcagtcc ctcagacggg tcatggacga gctgccctcc gatcacttcg
     4681 atgtgatcgt catcgacgaa atccacagaa taggatcgcc gacggtcgta aggatcttgg
     4741 agcacttcac gccgaaggag ttgctcagcc tctcgtcggt gactccggag cgcgcggaca
     4801 gcctgagcat ccacgatacg ttcttcgacg gtcgtatcgc agcggagatg cgtctcccgg
     4861 acgctctggc aagcggcctc ctgccttccc tccactactt cggtattgcg gacggtaccg
     4921 acctgcgaag gctggactgg aagcagggaa cgtacgaccg ggcttcgctg aacgctctgc
     4981 tgactgccga tcacgcacgg gctcagctgg tcatccgcgc catccgggac acggtccccg
     5041 acgtgaagac catgcgggcc gtgggcttct gccagtccgt ggcacacgcc gaactcatga
     5101 cccagtgctt ccgtgacgcc ggcttccgcg ctgtagccct cacggcggcg gatcgcccag
     5161 caacgcgtca ggagacattt tcctctctca gggacggcaa cttgcaggtc atcttctgcg
     5221 tcgacgcgct cagcgagagc gtccacattc ccgaggtgga cacactgctc ctgctgcgcc
     5281 cgacgtcgag caccctacag ttcctgcggc agttgggtgt cggtctccca cgcttcccgg
     5341 gcaagcctgt actcactgtg ctcgacttca tcggacacca ccgtaaggag ttccgcctcg
     5401 actatcagtt ccgggccatg acgaatctgg cgggcaggca gcttctccac cacctcgagc
     5461 acgacttcca ccagctcccc accggctcca tgatcacctt tgaccaggag gccaagagca
     5521 tcgtcctcga cagcctctgg gagcagatgc ggggcggcgt caccgacacg gcagatggca
     5581 gccgcccggt gggcgaaggt caacatgagc ggtcggcggc gccgactgcg gatctggtga
     5641 cggacaccga gccggcttcc ggacccgcgg caacggaccg attgagggct ttcgatcagt
     5701 ccccgcgtgt cgtcatgatg aaagggggga acgaaacggg cacaaacagc gcagtcggca
     5761 tcatgctgac cccccgtctc gtgctgacct gtgcctccat gttggatccc agcgcaagga
     5821 tgtggatcgt gcgcgcggac ggcacggaga tcgcctgcag aaccgtgtgg aagaggccgg
     5881 gggccctgga agccaccctg gtgcttgcgg aagagaacat cctcgagagc gaggaatggg
     5941 agcgactcct gccgtcccgg ctgaggtggg ggcgcatgcc caacagggtc atgtcacccg
     6001 tgcgcatcac cggcttccga cggtcgggca aacggatcga gctgaatggg caggcacggc
     6061 ccacagcagc gcaaatcgcc gtcgaagtca ccagctcagt cacagaaggc gagttggcag
     6121 ggttgccagg cgcgctggtg tcctgcaacg gcttctttgt gggaatggtc acccggcggc
     6181 acctacagcg tccccagctc gtggccgtgc ccgcggccct cctcctccaa gaccagggct
     6241 tccaccgtgc actggcgacg cacatgacga cgccgtacga gctggaggac gtagggatcg
     6301 agccgtcctc cgattcttgg gatggtcccc ttgccgtgtg ccttgccatc gaagcgcaca
     6361 ttgtcagcgg ccggaggggc tcagacgctc atcaccggga atcagcgctg gcacatgaga
     6421 tcagggaatc cctagttgcg atcatgcacc gagtcggcat cgttggtgta gtcgtcgagg
     6481 aagcggtagc tgatgcgaga gcagatctat tgatgagact ggacggcccg gcggccatcc
     6541 aagacatggg ccgagtgctg gccgaactgc agaccgctgt cgctacgcac catgatgtgg
     6601 cattcggggt cgcggcctcc atcggcgagg tgacggacac tcgcttgggt cttgccggtg
     6661 gagccgtgtc ggaagccgtc cggctgggca gcaactcgtt cttcagggag cagttgcacc
     6721 aggcggcgcg cttcgtcgac tcacccgtgt atttcgccgt gtccaacacc ctccgcgccc
     6781 ggatcgcagg gatgctgggc ccggcctggg agggccggtt cgtgtcgctc gaaccacatt
     6841 cgcaaccggc tcccgaagcg ggctggatgt acgaggggcc caccgaacag ctgggagggg
     6901 cgctcgccgc gattcgacac ggaggtctac tcccgtaacg gtcagttact gtcgaagcca
     6961 gttggacacc aagaacaagg ctcgcgccga cgcggagaag aaggtcggcg atttccgaag
     7021 agtggactcc gaacgcgtcg ccctggagat cgcccccgct ctcgcggccg tgcgcaccct
     7081 cgacctcgag gtgttccggg ccggcctccg cggggcggat aatcagcgct atctggccct
     7141 gcagaggacc gacccccagg gacaggtcgt gttgggcctc gtgctggcgc gcaacgccga
     7201 tatccacctt ccggccaccc tcggcctaca cgttgaccgt gtcgtcggcg acgacgacgg
     7261 gtaccgggtg atgccctcct ggctcacgta cgacaggctg cccaccgtcg tacgcgccaa
     7321 caaaaggagc ccgggcagca ggaacggcac gagcgaggcc tcccatgacg cctaccggga
     7381 cacggtcggc ggacaccttg tcatcgagac gcttctcgac gcattcgcgt tcttcgggcg
     7441 ctgcgacccc accctggcac ggcgcgcacc gggaacggat aacctggcgc acttcccgtt
     7501 gcccgccatg aacaccggtg acggctacga ctacgagcgc cgccaccccg accagcccaa
     7561 ccgggctgac ttcggcgcgg aggcccgccg gctcaccgag gacgtcccgc cctcggggtc
     7621 cggccgggag atctcctacc gcctcgacag cgacggcacg gccgtgtact gccggcacac
     7681 cgtcgaacgc ttcggtctgc gctcggcgtt caccgaatcc gcggctcaga tcgtgcgtga
     7741 catccgcgcc gggtacacat acgtcgccgt ggccaccgac ggcgtccacc accccgtcac
     7801 cgtggacgcc gacggatgcc cgtgggcgga cggcgtagtg ctcgaggact accccttccc
     7861 cagccccacc ggcatccgct cccccagaca tggctgacgt ggtggcagtt cgtgctcgac
     7921 gacccgttct ggcaccgaag gcagcgactg ggacactgag gaagcctggc tctacgaaac
     7981 gagagcgatc gatgagacaa gaggtcacgg gccgcaagcg ctacctcgaa tcaccccctg
     8041 tggctattgc tggccgcctc ggtgaccatg gccggtacct ccggcaacgc tggcgtccgg
     8101 ctgaggccag tggcctccaa cgaatatgcc ggggctgtct tcaggccgcc ggccaccaca
     8161 cagcccgctg cctcgaccgc cactaccggc ggctctccca cactgagcag tcaacgctca
     8221 tggggagcaa gccgattagg gcactcacga acacgcagct cacagtgctc aggtaccgaa
     8281 aacgccaaca ctgactatca gtcaactccg atgcattccg ctctccgaat tgagcaacac
     8341 gcagatcggc agcgaaggac tgctcacctt cagtcaggcc gcaacagcgg cgcggccgcc
     8401 cctgcgaggc acaaccggct aagcgcgccc cgatccccgg ccgcgccgcc cattccgccc
     8461 gtcccttcct ccttcacacc agccaaggga catagacaga gcagccacaa cggggatgtc
     8521 agcgatccga ccacggcaga acagcgtggc gacctgcacg gacacgggga ctgtcctgcg
     8581 ggccgcgcaa cacctagcgc aacccttggc gcaacctcgt gctcctgggc gaccggggtg
     8641 accggtcacg cggcccggac ggctccgtgg gcgcgggcga ggtggcgcag ctcggagcgt
     8701 gccgtcggcg ccgaggggac ggtctcccag tagggtgcca ccacagccgt acggataggc
     8761 gcagcaggcg gcggcgcaga gcggtggtgt cgcggggcag ggtgcggcga gcgcttggta
     8821 ggtggcgttc caggcggctt gcgtctgcac caggtcgtcg aggaagtcga tcacgcccat
     8881 accggcatta gatcgcttgc tcgaattacg tgtcacttcg gacgcgccgg actcgggcct
     8941 cgcggccgga gtgcggctcg ccgtggtcgc ccccgaccac ggcgcggcga tgggcgtcct
     9001 ggcgggcgat ctgccgggcg agaacgtcgc ggtcgacgta ggggtcgacg acggtgaggc
     9061 ccaggcgccg tggttcgagc gaagcggctg gacagggttt gtcagtcggg tccgggatca
     9121 tgtcggcatg ggtgacaaca agcggagaca gcggaacacg tatgaggtgc tgggactaca
     9181 gccgctgttc aatgccttcg gaacctctgt cctggcaacg ggtgtcttcg acagcatcac
     9241 gaagcggtac gggaacagca ccggcagttt gttcatggcg aggtccggtg tctacggcag
     9301 cgtcctgaag cagtatgggc gcggcatcgg cgctctttct ttcctggagc cgcagaggtc
     9361 gatatctgtc ggtgtcctcg actcggtgaa gacggggtct cttcttggtg agtccttctt
     9421 cggcagtcac aagacggccg cgctgggtct ggatgccttc cggggcagtg gcagcgtcgg
     9481 tgcttgggga gctgacccgt tcggctgggg gaagggcgcg gtgacgaccg gggtctacgg
     9541 cggcgtattg aaggcggccg gacctgacca gctcagtggc agcttcttcc cgacggcacg
     9601 tggcgccgct gcttcggtct ggctacccgg tctgctggac agtttcaccg cgcccttggc
     9661 gccgagcctt ccgcgccggg cggaggagct ggcagatctc ctgctgccgc ccaatctgca
     9721 gggcttctcc agtagcgagt ggtctcagct aatcgacatc acgaccgatg ctgggatcgg
     9781 cctcatgtgg gctcccggcg ccgggcacct gcgcgcgctt ctcgcggaag acagccggga
     9841 ggggcgctac gcctacctcc tgcagcatca ggacgaactg ctcgatgagc tgagcgcagg
     9901 gatgcaggag gtcaccgagg agcccttgca ggacctcgtg cggcttggca tgcgggtcat
     9961 cgagtgcgcg agagccggtc tgtgggaggg ggctctcgcc ctggctacga acgttttgta
    10021 ctccgcgatg gaagagcacg ggatcgagtg gtaccgccgg gaattccgca gtgtccgcga
    10081 ccacaataac cagccgatcc gaggaatcaa cggccccgga ccgaccgtgg aattcgtact
    10141 cagcaacgtc ccgatgcccg aacgccgggt cggaattttc gacctgcgca cgcacctggt
    10201 aacccggccc atgtcccatg tgttcaaaaa cagtgcgctc gtgcagggtc agcacaaccg
    10261 tcacgcggtg tgccacgagg cttcctacac ctcgttgcga gaggtgtacg tcctgcctgc
    10321 catgctcaac atgcacgccc tactgcgggt actggacgag aaaatgtcag acgacagccc
    10381 aagcccttga tccgaccgtg acagccggaa ggtcgcctcc cgcagtgtct cgtgagcgaa
    10441 gctcaccctt cgtcggtcag ggccttggtg aacaactctt cggagtccag cgaacggagc
    10501 agggggccga gaagcctgcg ggtcgccgtg cccggtgcgt cacgcagctc cgccagcgtg
    10561 gtaccggtgc tttcctcgta ggtgtcggcg ctgtacctgt gattgctggg ccagtgtgac
    10621 tgtccggagt acctgcggcg gccgcggagc ctgttggccc cgaccgcaac ggcccagttt
    10681 ccgtggtagc ccacgtcgtc ggagatcagg cgcgtcagct ccagcatgtg ccgggtgagg
    10741 atgacggcgc cggcgtcgaa gaggacctgt tcctcttcgt cctccgaagc atgactcttg
    10801 aggccgtcgg aaagacgggt catgaacagg cgcagtccgc cgccctcgaa gagctggact
    10861 tcgatcacgt cttcgtcgcg ccagccgccg tctgcgacat gtgtgcggtc ggagcggagg
    10921 ccggaggagc tgagagctac gcccctggcg cgcctgtgcc cttggtgagc atggctcagg
    10981 tcgggtttga agccctgacc ttcgagcgct gcccgtaggc actggttgtc ctggacgcga
    11041 cggatcaggg tgtgcaggcg catgttccag tccggggcgc cggtgatcgg gaggcacatg
    11101 tcccgtcttt cggcatagag gtaggggttc ttctcctggc ccgaggggtc gggctgggtg
    11161 aagcggccga tgttggcgtc gtagtagcgg gcctggaagt gatacagccc ggtggggtcc
    11221 tggtagccgc ccgcgaagcg gtagggctgg gcgaccggtt cggaggaccg ggccaggatg
    11281 cgcacgccgc gggggctgta ggcgtatgtg ttgaccttgt tgccgtcacc gtccgccagg
    11341 gcgaccacgc tgccgatggc gtccgtgagg tagtagtacg tcttaccccc ggtcgtcatg
    11401 gagttcaacg tgcccccggg ctcgcggttg aagcccatgt cgaccccggc ggtcgtcttt
    11461 gccgacagac ccagcgggcc gttgtggaag aaggtgtcac cgagcttgat gcgctcgctc
    11521 tggtcggtcg agccgtactg gccggcgtag gtcttgccgg cgaccgtgat cgacgacatc
    11581 tgagagtggc cagtccactt ctcggcggtg cgggcgtagt cgtccgtgga ggcgccggcc
    11641 gtctcgttgc cgatcgcgtc gtaggaccag gtgcagcctg accgaatacc gccctcaaga
    11701 tctcccgcgt cagtggccga atagcggtcg cggaattgga atttcgcttg actcgtcgct
    11761 agagagcggg gtaggggcga ttcgttcaga aagggtcctg gccgggtgcg ggggatcacc
    11821 tggccaggac cggctgtcaa cttgaacgtt gagcgttcaa ggagttgagg agggcagctc
    11881 cgcgctcggc atcatcgaca ctgaccgcaa agtttttgcc attgtgggtg tgggttacca
    11941 gacactcacc gctgcgcagc atcacagttg tgcccagccc gctcagccgg tatccccagc
    12001 caccgacctg ggaaggcgta cgcgtctcga cgcgggcaga ggcaatgtca tcggccgccc
    12061 aacgtcgcgc cggccagccc agcggcccga aggccacctc cagacctcgc tcactgaccc
    12121 gtgcctgcac cgaggcgaag ccgagcacca ggacagaggc cagagcgaac ggcccggcca
    12181 gcagtgcagc ctcagccccc atcaaacccc ccagtcccgc cacgacggcg gccactgcta
    12241 cgacacctgt cacggcggct gtcgcatgga gccaggggtt ggacgtgcgg gagagccaca
    12301 cgaagcgctc tcctgcggga atctccatgg tcggtccgcc tcctgtcggc accgcggccg
    12361 gagtgcggcg actggccagc aaggcggccg cgcccacgcc gacagccgct acgagcgtca
    12421 cgacgacaga gaccgtcacc gagtccgcct cgcgccagtc cgcgtggtct agattcgccc
    12481 gcacgatgga cgcctggccg cccacgagca tcacaccccc ggacccgagc gtcgcgccga
    12541 cccacccccc tactccgccg cttgaagtga cacgggcccg ccaccacacc agtgccacaa
    12601 gcgccgctgc caccccccag atcagcgccg ggaagagcga cgcggcccac aaaggcatgg
    12661 aactgtcggg cttgcccgag ccggcgtccc agtgcgtcgc cagccggtca ggaagccggc
    12721 caccggcgac aagcggcagc gccaccagca gcgccaggat gcctaacacc cagccggtga
    12781 caccccacgc cgcagcgctc ctgcgtcccg cacggccggt cacgaaatcc ccctgatcat
    12841 gtcgatcaga tcgttcctgc tgtatccgag gcgcgccgcg tcggccacga catcacggac
    12901 gcgatccagc aacgccgagc gttcagccgc cccatgggcc accgtcacgc ctctgccgcg
    12961 ccggaactcc agcactccct cgtcacgtag cgctcgaaga ccacgcagca ccgtattcac
    13021 gttgattccc agcacctggg agaggtcccg tgctggggga agccggtcac ccggctcaca
    13081 ctccccctca gcaatggcac gtcggatcgc acccgccacc tgctcatgca gggggcgatt
    13141 gtccgcagtg ttcagcctca gcaacatggt actaaagaag atagcaccat acgctcgaag
    13201 agccgaggtg gcgatgactt cggcacagcg cccggcgtct gcggtggaag accagtccca
    13261 gcggcgaacg cttcgctcca gagcaggcgt ttcccaccca aagttgatgg gttcgggaga
    13321 cactggacct cctgccaggg cagcatcgga atggtcttgg tgaaggtgct ggtcatgccg
    13381 taagaaagag gagaccggtg gactggacac tgggcgaaaa attcgagacg cctgacggaa
    13441 tgctgcggtg gaggatgttg ggcagcgggg atccggtcgt gctggtgcac ggcaccccat
    13501 attcctcctt cctctggcgg gacatcgctc cagcgctcgc ccgtacccgc acggtcttcg
    13561 tcttcgacca tctcggcttc ggccggtcgg atcagggcga ggcccaggac ctcagcctgg
    13621 cggctcacgc gaggaacttc gcccggctcc tcgaccactg gggactgtcc cgccccagcg
    13681 tcgtcgccca cgacatcggt ggggccgtgg cactgcggac actgctgctg gaggagagga
    13741 gctaccggga cctgaccctc ttcgacgcgg tgagcggcgg acagtgggaa cgggggcttt
    13801 tccggctcat cctggagcac ccgggagtct tccagcagct tccggactac gcgcacgaag
    13861 cgctggtcgc cagccacctg cggcacgcga cgcatgtcgg cttgcggccg ggggtccttg
    13921 aagcgttcct cgcgccttgg cggggagccg cggggcaggc cgcgttctac cgccagtaca
    13981 gccagatcaa gcaggcggac accgccgcgt acgaacacct gctgggcggc atgtcgcttc
    14041 cggtccgcat catctggggt cgagaggacc gcatcctccc cgcggagtac gccgaatggc
    14101 tgcacgagca catcccgcac gccgagctgc actggatcga ggatgccggc cacctcctcc
    14161 aggaagacgc accaggacag ctgaccacct acctcaccgc cccgttcccc tcagacaagt
    14221 gagccgggcc agcctccgga ccgggtgtgg tcggcgtggt tgtgcggcga tcatctggta
    14281 tccgagcggc gtgaggtgtt gcgtcagttc gccaacgggg tcgatgccgc gggccggcgg
    14341 gtgcaccggg cgttcctggc aggttgtcgc gtgctcgggg agggcgtgga catcaccggt
    14401 gagcgaggcg tggaggccgt ctgcttcgcc gacacccgcg gctcccaagt agagatcgtg
    14461 cagaacatcg gccgcgcgct ccggctcaac gaggacggca gtaccaaggt ggccaggatc
    14521 atcgtgccgg tgttcctgga gcccggcgag gatccggccg acatggtcgc cagtgcctcg
    14581 ttccgccctc ttgcagcggt cctccagggc ctgcgctcgc atggcgaacg tctggtcgag
    14641 cagcttgcct cccgggcact cacgggcggg aagcgcaagg tgcgtgtccg gcgcggcgca
    14701 gaggggcgga tcgtcagggt tggcggtgag ggcgatggtg aggggcagga ggacgacgtg
    14761 caggccgtcg aagcggccct gctgcacttc tccagcccgc gcgacgcggc gaccatcgcg
    14821 gccttcctgc gcgcccgggt ctaccggccc gagtccctgg tttggcccga gggctaccgg
    14881 gctctgctcc ggtggcgcgg ggagaacaag atcaccggtc tctacgcagt tccctacgac
    14941 accgaggtag aggtcggcgt cacccaggac ttccccctcg ggcgaggggt gcgccatcag
    15001 cggaaggcgc tacgggccgg agagccggag gaccggcgca agaccctgct ggatgtgccg
    15061 gaggccggga tggtctggga gcccggcgag gaagcgtggg aggccaagct cgccgcgccg
    15121 cggtcctgcc ggcgggctat ggggcacctc gcgccgcgtc aggacgcggt gtggggcgag
    15181 ggcgggacga tggtgcctat cgggcggcac atggccaacc tccgacggaa gggcggcctg
    15241 ggcaaggacc cgaagcgtgc gaaggcgcgc gcgcagcagc tggcggcgat cgacccggac
    15301 tggaactgcg cgtggctgct cgactggcag cggcactacc gcgtcctgtc cgccttcctt
    15361 cgcgacaccg cccgcgagca tccccgcgag gccgttcgtg ccctggccga cgcggtcagc
    15421 gaagcttgcg gaggccatgt gggggacgac gccgtcgtcc tgtgcctgga ctggcacggc
    15481 cctcgccccg agggtgcgtc gtgaacgcgg aggcttgggc tgaccgtgcg gctcagtcgc
    15541 tcagtgcggg gtcttcgggt gctgctcggt tcggttcgca cctccgagct gccggggggt
    15601 cctgccttcg tgtgccggtc gccggaaggt caccggggtg gggcacctgt tcggcttgga
    15661 tgttccgtgg gcggttgagg tacggcttct cggcacggtg gtggtcgctg tcctgcccgc
    15721 gtgcggcagg ggttcggcga ctgacggcgt cgcgcgggcc gggtcggtgg aaggccgtgg
    15781 ccacggcgtc cgcgagccgg ttcagtacgt cccgcgagag ctgcaccgag ccggtgaacg
    15841 agaggaagcc gtgaacggct ccctcgatcg ggaggtgctg gacgggcacg ccggcgccgg
    15901 ccagcttgcg ggcgtagtgg tcgccctggt cgcgcagggg gtcgttctcc gcggtggcga
    15961 tgacggcggg ggcgagtccg gccagttcgt cggagcgcgc cggtgagacc cgcgggtcgg
    16021 cgccctggtc cggggtgctg aggtaggcgc cccagaacca ctcgaggtag gaacgggaga
    16081 ggaccggtcc cgccatgttc tcgtacatcg aggggctgtc gtcgaaccgg tcgaccgccg
    16141 ggtaggcgag cacctggagc gtgatgcgcg gtcccccgcg gcgcagggac tcctgtgcga
    16201 gaaccgcggc gaggttgccg cctgcgctct cgccgaacac ggcgatgcgt ttcccgtcgc
    16261 ccccgaagcc ggcggcgctg tccgcgaccc aggtcagtgc ggcataggcg tcgtcgaccg
    16321 cggccgggaa gcggtgttcg ggtgccagcc ggtagtcgac ggagaccacg atcgttcggg
    16381 agcggacggc cacggtgcgg gcgatgttgt cctgggtgtc caggtcgccg aagacccatc
    16441 ccccgccgtg gaggaagagc gtcacgggca gcggtccggc gttcggctcg gtgacgggcc
    16501 ggtagaggcg cacgggtacg gtgcggccgt cggccgcggc cgcggtgtcc cggacgtcgg
    16561 cgaccggtac gggagcgccg gccagggcgc cgaaggcgcg cccgaacgcg cggttctgcg
    16621 ccaccgtcag ggtctcgggc gccggtccgc cttctgcggc cacgcgctgg agcagggtct
    16681 cgatctgcgg gtcgaggggc atggcactct catctgtcct gggaaacggc cgtccggtgt
    16741 ggaatgacct ttccaggatc atcgggggca cgtgattgga atgtcaattc caacttgggt
    16801 agcgtgggcg catgagcgca ccaggaaagg ccggagagcc gaaggagcag cggctcaccg
    16861 agggcggccg caggacccgc gaacgcatca tcgagaccgc tgcggaactg atgttccacc
    16921 gcggcgcggg aggcacgagc atcccggaca tccaggcggc cgccggggtc agcgcgtcgc
    16981 agatctacca ctacttcggc gacaagcagg gcttggtcct ggcggtcatc gaccatcaga
    17041 cggacgccca gctcgcccgg cagcgtccgc tgctggacag cctggacagc atcgaggccc
    17101 tgcgcgcgtg gtgcgacacg gcagggagcc ggcaggacgc caggggatgc gaaggcggct
    17161 gcgagatcgg ctcgctcgcc ggcgaactcg ccgacagcga ccagtcggca cgggccagac
    17221 tcgtctccgc cttcgaccgg tgggaagagc ccatcaggtc gggactggca cgcatgcagg
    17281 cacgcggcga gctgagcgag cacgctgaca ccgccgcgct cgccaccgct ttgctggccg
    17341 ccgtccaggg gggcatgctg ttgtcccagg tccgccgctc gagcaccgcc taccggcagg
    17401 ccgtgtcagc ggtgatcgac cacatcgaga gccacctcgt ccggtagcgg cccaggcgtg
    17461 ccggcccacc ggcgacaccc tttcgacccg ccggcacaga ggtcgggaac aggcgctcgg
    17521 agcggaccga gctcgtcgac gccggggccg gggtcgagtg acttgtgcgt tgtccgccgg
    17581 cggtgctttc ccgagcgggc cgttcgggcg gagccggacc gggcacctgg agcccatgac
    17641 ccatgacgca agccgcatcc ggctggtgca gaccgtgctc gacagcaccg acgcccgtga
    17701 actcgccgag ttctaccggt ccctgctggg gctcgactac gcagaggggg acgagccgcc
    17761 cccggccggt cagccggacg agcacggtgg ggactggctc gtcctgcgca atcccgacgg
    17821 cggaccgcag ctcgccttcc agcaggtgga gcgcctgcgt gaacccgact ggcccgacgg
    17881 cccggtgccc cagcagatgc acctcgacct gagcgtcgcc tcgttggagg aactgcggaa
    17941 ccagcacgag cgcgtgctcg ccctcggcgg cagcctgctc agcgaccggg accggccgga
    18001 tcccgacgac gaggaacgct tccgcgtcta ccgggacccc gagggccacc cgttctgcat
    18061 cttcgtcgcg gagcgggacg agcagcccgc gggagcaccg tgaacgacgg cggacgcccc
    18121 cctgcgccgt gctcgacgcg gagatcatcc cagccggtcg gccgacgcga cggtgcctct
    18181 cgcggcggaa gcggaaacgg tcacgatgtg cccccccctg ccctccgggg ccccggaggt
    18241 tttctttggc ggagaagccg acgcacgcgg cctcccgccg cccgcgggga cgtgtcccgc
    18301 gccccggccc ggcgcgcagg caccgtgccg gtggggggtg cccgtccgct gtgcccgcac
    18361 gcggtgctgc gggggcgggg gcggcctcga gggccgcgga ccggagcgag gccgccgtgc
    18421 ccggcagtgc ccggggcccg ccgggtcacg tccccggcgg gcgcgccagc gcgtcgacgg
    18481 cggcggagaa caaccgcggc agccgctgcg ccgcgggcac cagcgccgcg cgcagcgggg
    18541 gcaccctcgt cgcgccgagc agcgcgcgag tcagccggcg gtagcgccgg gtgaggcggc
    18601 gccactcccg ttcgtaggcc gccgggtcgc cgtcgacgac ggcccgcacc gccgccggcg
    18661 cctgcgcgag cgccagcgcg atgccctcgc cggtcagcgc gtcgacgtag ccggccgcat
    18721 cacccaccag cagcacccgg ccggcggtgc gcgcgctcgc gtcctggcgc agcgggcccg
    18781 ccccgcgcac cggtgtggcg ctttcggctc cggccagccg ctcccgcaac tcggggaagg
    18841 cggcgaggtg gccgtcgtag ggtccccggc cggcggtgag caccgcgacg cccacgaggt
    18901 tgtcggacac cggggtcacg taggcctccg cgtcacgggc ccagtgcacc tcgacgtggt
    18961 cgctccaggg ggcgagcacg tagtggcgcc gcagcccgtg tcgccggggg gcccggcgcg
    19021 gccggtgcag ccccagggcc cggcggatcg gcgagtgcag gccgtcggcc gcgacgaggt
    19081 ggcgggcacg ggtgccgtcg gccaccacac cgtcctcgtc ctgctcgaca cggcgcacgg
    19141 tgcgctgctc gacccgcacc cccgcggcca gcaccgcctc gcgcagcgcc gcgtgcagca
    19201 cggtgcgccg caccccgcgc cccgggcccg cccggaaggc ggcgtcggcc cggtgcgccc
    19261 cggctacgta ccggataccg cgcaggtcgt agcccggcgg gtggacgccc agtgctgtca
    19321 gctcggcgac ggcgcccggc atcagccctt cgccgcacgc cttgtcgagg gtgccggcgc
    19381 gctgttccca gacgaccgct tcgagccccg cccgggccgc gtgcagagcc gtggcgagac
    19441 ctgcgggtcc cccgcccacg acgagcaggt ccatgcgtgc ccctctcagg ccggccgcgc
    19501 cagggcggtg tcctcggtgc ggatgcgggt ggcgagcagg aacccgttca gcacggtgaa
    19561 cacgagcgcc gtgacccagg ccgagtgcac cagcgggagc gcgagccctt cgacggcgac
    19621 ggcgacgtag ttcgggtgcg acagccggcg gtaggggccg ccggtcacgc gcggagcacc
    19681 gggcacgatg atcacccggg tgttccactg ccggcccaga gtggcgatgc accaccagcg
    19741 cagcgcctgc gcggccgcga ccagggcgag catggtccag gcgaggaccc atacggcgtc
    19801 cggccggcgc acccacacct ccacgagcgc gccgacgagc aggcccgtgt gcagcaccac
    19861 catgaacggg tagtggcccc gcccggactc cacgccgccc cgtgcaaggc tccagtgggt
    19921 gttgcggcgg gagacggcca gctcggcgac ccgctccaga gcgacggccg agaccaggac
    19981 ggtgaacagg acctggccga tcatctctcc cccggggcgc gcaggaggac gagttcgcag
    20041 caaaagcccg ggcccatggc gagcatgagc ccgtgggagc cgggcggcgg tgggcggtcg
    20101 gcgagggtgt ccgccaaaac gtgcagcacc gaggcggagg acaggttgcc gatgcggcgc
    20161 agcgagtccc aggtcacggc cagggcgtcc cgctcgacct cgagggcttc ctgcagggcc
    20221 tcgaggacct tggggccgcc ggggtgcgcg acgtaccagc cgaggtcgtc gtcgctcagg
    20281 tggtggtcgg cgaggaagcc gcgcacgtcg tcgccgacgt accggcgcac caggtcggga
    20341 atcgaggagt cgaggacgat cctgaacccg ccgggcccca cgtcccagcc catcgtgcgc
    20401 tccgtgtcgg ggtagaggcg gctgcgcgag gcgagcacct cggggcgggc ggggtgctcg
    20461 aagcgtgcga gcggatgctc ggcaccgacg gcgaccaccg ctgcggcgcc gtccccgaac
    20521 aggccgctcg ccacgaggtt ggccagcgag gtgtcctcgc gctgcagcgt gagcgagcac
    20581 agctcgaccg acatcagcac cgcgaccccg tccggccggc cgcgcagcag gtcgtgcagg
    20641 cgtgcgatgc cggccgcgcc ggcgacgcag ccgaggccga ccagaggcag gcgcaccacg
    20701 tcggggcgga gcccgatctg cgccgcgacg cgggcctcga gcgtggggac ggccagaccg
    20761 gtcaccgtgc acgacacgat gtagtcgacg tcgctcggcg tgaggccggc gtccttgagc
    20821 gcgtcgacga ccgcgcgccc gccgagctcg acgccggccc ggatgaagac gtcgttcgcc
    20881 cggccgaagt ccccgagccg ggcgtagctc tccagcggga gcacgctgtg ccgggtctcg
    20941 acgcacacgt tgcggtggaa ccgctcgacg acgccgcgct cgagcgtgcc ctcgaccagc
    21001 gtggtggcga aggactcggt gatctcctcc tgccggtggc ggtgctcggg caggacgccg
    21061 cggacgctga ggacgcgcat gctcatgctg gctcctgagg ccggccggac ggacggaggc
    21121 aggcgacgaa cgcccggccg aggccgagcg cgacggcggg ggtgagccgg ccccgggcga
    21181 gaccgagttc cacgaagtcg tcgaagacgc gctggtcggc ggccgaggcc cgcagcccgg
    21241 cctcgaggac gtgcgcgctg cgggcgagcc gggcggccag ggcggtgtgc cgcaggtggg
    21301 gcagcaggat cgggcgggtg gcgcgggcgt agcgctgccc cgcctgctcg ggccgcccgt
    21361 cacgcagggc cgcggcggcg gcgcgaccgg ccgcgatgcc ggtggccacg gcgtagtgga
    21421 tgccctcccc ggtcagcggg ttcaccaggc aggcggcgtc gcccacgagc agtacgcggc
    21481 cggtcggaag gcgccggcgc gccgtcgaga gcggcaggtg gtgcccggcc cagtgccgtc
    21541 cgccctcggt ggcgccgggc aggagcgcct cgaggcgctc gagcaggtgg gcacgcgtcg
    21601 gggtgggacg gtcctggtgg aggaactcgc cgtatccgac gttcgccagg ccgtcgccgc
    21661 ggtcgaagga ccaggcgtac gacggctggt gccgggtgcc gaactcgatg acctgcacgc
    21721 cgcgccgccc ggatccgacc ggggcgtagc cgcgcagcgc cagggccatc gggccgcggg
    21781 gccggccgag cgcgcgtcgg acgaccgagt gggcgccgtc ggcgccgacc acgaccgcgg
    21841 cggagagctc cccgtccagg accaccgcgc cggcgcgctg tcgcagatcg cggacgcggt
    21901 ggcaaaggag gtgggccccg gcggcgacgg ccgcgtcgac cagccgggca tcgaggaccc
    21961 ggcgcggcac cacccacacc gggcgggcca tcggccgctc ggcggccagg ccgccccggc
    22021 ccaggcgcag gcggccgacc ggcacccggt cgtcgaggag gccggtgacg ccgaccccgg
    22081 cgaggaggtc gaggacgtgc ggggccaccc cgtcgccgca ggccttgtcc cgcgggaaga
    22141 ccgcccggtc caagagggcg acgcgcagct ccggggcggc gcgcaacgcg cccagggcgg
    22201 tggcggcacc ggccggtccg gcgccgacca ccgcaaggtc ccagtgggcg ggtgcgggcg
    22261 ccatcaaccg gccgccacga gcagcacgac gtcgagcagg gcgatggcca gcgcggcccg
    22321 gaaggggacg cggccccggc cggtcagcgc gaacaccgca aggaccgcca ccagcacgag
    22381 ggccgcccgc ccccctgccg aaggaggccc ggcgggggcg aacacggcca gcagtgaggc
    22441 cgcggacagc agcgcgacgg ccaggacgcg cgaggagcgt tcgccgatcc ggtgcggcag
    22501 gccgcgcacc ccggtgcgtt cgtcgtcggc gaggtcgggc agcgtgtcga gcaggtgcgc
    22561 cccgaccccg agcgcggcgc cggcgccggt cgtccacagc ggcgcccagg ccggggcggg
    22621 gccggcgagg gtgacgagcg agggcagcgt cccgaaggca ctggcgtacg gcagccacga
    22681 ccaccaggtc gccttgagcc cgagattgta ggcgtggccc gcgccggcgc ccaggaggac
    22741 gttgaccagc gcgctgcgcc agccggtgag cgcggacagc acgaggcagg cgagggcggc
    22801 cgcccccagg gcgcgcaccg cccaggcgac cgggagggcg ccggtggcca acggcttgtc
    22861 ggtgcggccg gcggcgcggt cgcgggagag gtcgcgcagg tcgttgcccc agccgatcgt
    22921 gagctggccg gcgaggaccg ccccggtgag gacggcggcg tcgagcgggc gcaggccgct
    22981 gcggagcgcg agcaggcccg cgatgacgcc gaccgccaga gccggcccgc cgtgggcggc
    23041 ggcgagcagc gcgagcacgg gccgcggccc ggagcgggcc ggggccgcgc cggcggtcac
    23101 gggcgccgcc gcacggcgac cggcccgtga cggaccgcgt cgccgagcgc gcccaggacg
    23161 gtgcgcgggc gcagcacggg ggtgcggccg gacgcggcct gccgcatgcc ctcgatcacc
    23221 tcggcgagca cctgcgggcc gtccctggtc ggggcccagc ccagttccgt gcgcgcgcgg
    23281 gtggtgtcca gggtcgggag cgcgaagccc atgtcgagcc acccggtgtc gacctgttgc
    23341 aggtgcgcgt gccaggcggc cgacacggcg gcgcggacca cggcaaaggg cacgtgcacc
    23401 agcctggcgt cgagcgcgtc cgcgacgacc gccgcggtca cgggcgtgtc ggcggcgagg
    23461 ttgaacggac cgcccgcgcg ccggtgcagc gccgcgacga tcgcctcggc gacgtcgtcg
    23521 gtgtggacca tctcaaaagt cagcctccgg tccatcggca ggatcggcag caggtcgagc
    23581 accctggggg gcaccggggc gggcacgccg tagcgcagga gggcgctgcc ggcggcgcgc
    23641 tgtccgacga tccccggccg caggcgggtg acgagcgtgc cggcgccgga ggtctcgtgc
    23701 cggtcgagga ggcgttcggc cgccgccttg tgccggctgt agcgcgagct gcgcacgccc
    23761 ccggtgggcc aggactcgtc gaccgggcgg tcgtccttct tcggtgagta ggcgccgatc
    23821 gaggacatgt ggaccaggtg cgggacaccg gtctgggtga cggctctcag cacgcggcgg
    23881 gtgccgccga tgccgagccg ggcgaggtag gcgggatcgt gggagggctg gaagccccac
    23941 gccaggtgga cgatcgcgtc cgcaccggtg aacgcctcca cgagcgtgtc gtggcaggcc
    24001 tcggtgctga ggtccgccga gcgccagtcg acaccacggc tgccggggcc ctcgggcagc
    24061 cgccgggcca gacccacgag gtcgtgcgtg ccctcggcac gcaggcgtcg cacgacgacg
    24121 gaaccgatgt tgccggtcgc cccggtgacc acgatgcgca tgcaggagga tgccccgtcg
    24181 ctcccccgct cacacggggc gctccggcat ccgggggacc cccgggtcat ccgggtcacc
    24241 cggccggtgt cctgcgtgtc acgtgcgtgg cttcgttcgt cttcggcggc ggtgttcgtc
    24301 gaagggtttc gtgccggtgc gtcccgtgcg acgtgtgatc gcgtgttgac taccggtcag
    24361 accccgaagg gggcttcccg ctggggcggg atcggggggt tcaggacatc gcgggggcgg
    24421 gtgatgcctc ggcgccgtct cggaccgtcc ggtgcatcgc cttacagttc ggcgtgttcg
    24481 ggcggttcga ggacggtccg gtccggcgcg tcgactgcgg gcgtgcgaag gcccccctcg
    24541 gggggtgctg gtgtcggttt tgaggggcca cgggtcgggc acggcggttc gccgtcagga
    24601 gggctgtgcg agagccgggg acgctgcggg cacagctcgc tcggcttccg gggtgtccgg
    24661 ttcgtcggcg gggcgggcag cgcgttccgg cacgccgcgg agcacggccc ctcgttcttc
    24721 cacggctgcg tcgtcccgcg cactcgtgca cggtgggcgg tgggcggtgg gacggcgcgg
    24781 acctcggtgg ggcccggatt cacgtctgcc ggggcggcgg gccggccggc caggcccggc
    24841 cggccccacc tggcgggctc gggtgggggc cgcgcagcgt gcgggccgtg ccgggctgca
    24901 ccgcggcgcg cggccttcgc cgtccgtgac ggccgtggac gtgccggcgt cccgcttgtt
    24961 ctcgccggag gcgaacacgg cgcggtcctt gcggccggcg gccgggcggc ggacccggat
    25021 cccggtggcg ccgccgatgc cggtcgttgc gctcgagccg ggagggtcga cgccctcggc
    25081 cgaagaccgc agccgcacgc cggggctgac ggcgcggcct cgctcggcgg gcggggccgc
    25141 accgcaccga cggcccccgg gggatggtgg agcggtccac tgcgaaccag cgggccggca
    25201 cgtcgtggcc ggcaccgtga cggagctgga cgggcgtggc cggaaaccgc tcggcgaaca
    25261 ccggccggtg cttcgcaccg gcgcccacgg cccgcttccg cggccgagcg gcacgcccgg
    25321 ctcggtggcg ccccctgcca caacgggccg ctctcctcga cgggttcggc agtcacgccg
    25381 gcctcaggcc cgtgatccgc cgattgccga tgatcaccgc acgcgtcgag tcccccgcca
    25441 cccgaccgtg atcgaccatt caggcccgac gtcccaccgc ccaccgtgca cgagcgcgtc
    25501 agcgccgtcc cgtccctcca cgaggctgag gggcatgctg cgtcagggtc ggcgtccagg
    25561 gcgccgggcg agcgaagcga acgcccgcgg tctccggtga ggaggcgcgg gggtcgccgc
    25621 caccccaggt cggggccggg cagccggtgg aaccgctcga gcgcccggcc gtcgtcggcg
    25681 gcggtcgccg cctcgtaccg gccgtccaga gctttggtcc gcggggtgca gagccgcccg
    25741 gtgcactcgt ccagcaggaa ccgggcctcg tgcagcccgt ttcggcagcg gaggtcgtcg
    25801 gtgcactcgt ggatgtcgtc gccacggccg cgcccgatga cgcctgccgg ggcggcccac
    25861 gcgtccaccc ttttctgcgg ccgtgaatgc cgtccgccgg ccgcgccggt gccacggctc
    25921 ccccgccccg gccccggcag ccccgggcga aaggacctca cgcacaaccc gtccgggcgg
    25981 ccgggacatg ccccgccgga ggccgcggcc cggaacatga tcaaggtgag acggtctcac
    26041 cgtggccggt gtgatcacgg cggtccacgc gttgcccgtc gcccggtcgg ggatgcgggc
    26101 gccgcctgcg tgagtcgcgg tgcccggcac ctggcggaac aatggggcac ggccccgtcc
    26161 gccgttggac tcaagggaga cgcgcatgtc ctcgaagagg cgccggaaga agaaggcacg
    26221 ccgcaagcac gcggcgaacc acgggaaacg accccagtcc tgagacaggg cgcgcacggc
    26281 gcccgctgcc cgcactcctc gaagcaggcg gatcgggagg gccgagggag ctcttcgtcc
    26341 cggtggccgt cgcgctgcgc tgtccaccgg acaggacgca ccttgccccc ggcccccgcc
    26401 cttggggtcc gcggcacgct cgccgagcgg ctcctcggcc cggcacgaaa gacgccggcg
    26461 gccgggtcgg ccgagaccga ccgccgtgac ggtgccggca agccgggcgt gaccgggcgc
    26521 ggccgcttcc ttccgaaaac tggatcctcc gggccgcttg ccacgggcaa ggccctgcgg
    26581 cacatcgccc tcggcctcgc cgtgcaccgg ccggggcggg acgatccgct tgcggcacga
    26641 cggcgcggag accatccccg ggggggcgta tcgctgagcc gaaacgtctc cggcgtgccg
    26701 cccggcgcgc ccttcaccga cggccgggac gtcgagccgt ccgtcgagcc gtgcgatcgc
    26761 ctcatcgagc gggacctgtt cgggagtgcg atcgcctcac cgagcgggac ctgttcgggc
    26821 cggacggcga ccctcccgca gtgagcggtc gcacgctcct gccgttgccc gtccgccggg
    26881 tctccgctca cggcttcgac gagccggccc gggcgctctc ccggcgggcc gccgcgcagg
    26941 catcgtcgca cccggcctcc ctctggggct ggaccggcag ccggccaacg gatgcgcgag
    27001 ctcaatggcc gcaaggcgac cagaggccgg ccgggaaggg ccctgccccc ggatcctgaa
    27061 cacggctcac gcggctggtg ccggcgcagc gggtgtgagg tggagggcgt ccccgaaaac
    27121 aaccggcgac cgcccaccgg ggcgggcgtg tcggcggcgg acggggcggc ggcggggccg
    27181 tccgacggcg gcgagtcgga cctcgcgttc gccgggccgg ccccacgggc cggttcgccg
    27241 ggccggttcg ccgggccggt tcgccgggcc ggttcg
//
