LOCUS       NZ_FNDP01000023        21628 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Pseudobutyrivibrio sp. 49, whole genome shotgun sequence.
ACCESSION   NZ_FNDP01000023
VERSION     NZ_FNDP01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudobutyrivibrio sp. 49
  ORGANISM  Pseudobutyrivibrio sp. 49
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Pseudobutyrivibrio.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 14:11:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,130
            CDSs (total)                      :: 3,071
            Genes (coding)                    :: 3,034
            CDSs (with protein)               :: 3,034
            Genes (RNA)                       :: 59
            rRNAs                             :: 4, 4 (16S, 23S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 6 of 37
            Pseudo Genes (incomplete)         :: 31 of 37
            Pseudo Genes (internal stop)      :: 2 of 37
            Pseudo Genes (multiple problems)  :: 2 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:08:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10639
            Orig. end                         :: 32267
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNDP01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21628
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21628
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21628
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11628](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11628)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            431..691
                     /locus_tag="BLP54_RS13900"
                     /old_locus_tag="SAMN05421493_12312"
     CDS             431..691
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BLP54_RS13900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAMN05421493_12312"
                     /product="hypothetical protein"
                     /protein_id="WP_090170718.1"
                     /transl_table=11
                     /translation="MIDRGRLLSLGYYKKAPSFTGSDKNKCYKIERFREEDSEVDMFKA
                     TIWPGPFSSENTPEESKQSKLAPFTEDGLQELVDWMNSLDI"
     gene            complement(688..2289)
                     /locus_tag="BLP54_RS13905"
                     /old_locus_tag="SAMN05421493_12313"
     CDS             complement(688..2289)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="BLP54_RS13905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12313"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_090170720.1"
                     /transl_table=11
                     /translation="MKQGKNLFSFHRKLNNVMLVIAIVGLIICYMMTRDVKKDETSTSR
                     IEPYQVALLEDGSKEYFIDLSSYDSQYSGLVFFTAHQSVTVYNAGHEIYSFTKTGGFWG
                     STPGAKYNFVSINEKMQNVAVILTPAYDIVSEKVPEFYIGNTYQIYSEFLRDSIPRLIA
                     SIFIVIFSLTLFAYYIFMNKRLNLGKDLIYLGYFSLFIGVWSTNETIAWTLVSENRIFD
                     SIIPYICLMLSVPPFVLFFDSYLGINGKIIKKIILWASMVEFITVTSMHFLKIREFREN
                     LMFVQLMITVAVAYVVGAIILQLLHRDFSRQVIICTIGVSLFLIAMVVDVINYYRIIGD
                     ADRLGRYMVLIFVLLLAWDLIRGTNELIEKGRRARQLEIFALTDSMTGLYNRNAFESQA
                     ESDRKLDGIIAVVADANGLKACNDTYGHEAGDEYITLVAEIFNGVFGRYGTCYRTGGDE
                     FCCIIPSSKAVNMERLKKLFMTKIYTANLEGKYQYSIGVAIGAAMFDSELDKDFRALVK
                     RADESMYENKKASKTV"
     gene            complement(2404..3063)
                     /locus_tag="BLP54_RS13910"
                     /old_locus_tag="SAMN05421493_12314"
     CDS             complement(2404..3063)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-138). E-value: 6e-21.
                     Score: 67.1. Matches aSDomain:
                     nrpspksdomains_BLP54_RS13910_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548733.1"
                     /locus_tag="BLP54_RS13910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12314"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_090170723.1"
                     /sec_met_domain="PF00561 (E-value: 4.2e-18, bitscore: 57.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.2e-15, bitscore:
                     48.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYIQLNSQIICYERTGDQGTPVILIHGNREDHHIFDPLVERLSKY
                     NVVYAMDSRGHGESATPKEYHYSDMANDVINLIKGLDIEKPYLIGYSDGGIISLLVAMQ
                     ASELLSGIVCCGANLSPAGLHHRDLREMKKDYKKYNDPRTLMMLQEPDINPEDLKNITV
                     PAMIFAGEDDCVKQKETEKIAQSIPNSVLKILSGENHSSYIVEKDTLYPHIYNFIR"
     aSDomain        complement(2650..3003)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLP54_RS13910_Abhydrolase_1.1"
                     /evalue="6.00E-21"
                     /label="BLP54_RS13910_Abhydrolase_1.1"
                     /locus_tag="BLP54_RS13910"
                     /protein_end="138"
                     /protein_start="20"
                     /score="67.1"
                     /tool="antismash"
                     /translation="PVILIHGNREDHHIFDPLVERLSKYNVVYAMDSRGHGESATPKEY
                     HYSDMANDVINLIKGLDIEKPYLIGYSDGGIISLLVAMQASELLSGIVCCGANLSPAGL
                     HHRDLREMKKDYKK"
     gene            complement(3082..3843)
                     /gene="dapB"
                     /locus_tag="BLP54_RS13915"
                     /old_locus_tag="SAMN05421493_12315"
     CDS             complement(3082..3843)
                     /EC_number="1.17.1.8"
                     /GO_function="GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743356.1"
                     /locus_tag="BLP54_RS13915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12315"
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="WP_090170726.1"
                     /transl_table=11
                     /translation="MTKIVMHGCNGHMGRVITDLCMNDSAATIVAGVDKFKGIDNDYPV
                     FDSLEEVDVDYDVVIDFSTAAAVDGLLDVCEKTGKPVVLCTTGLDDNQLAHVDAASKKV
                     AILRSANMSLGINTLFDLCKKATQIFADAGFDIEIVEKHHNQKLDAPSGTALALADACN
                     DALDEKYEYCYARADRREKRPKNEIGISAVRGGNIVGEHEVIFAGLDEVITIKHTAYSK
                     SVFAKGAVEAAKFLAGKSAGLYDMKEVIAEK"
     gene            complement(3945..4424)
                     /locus_tag="BLP54_RS13920"
                     /old_locus_tag="SAMN05421493_12316"
     CDS             complement(3945..4424)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548731.1"
                     /locus_tag="BLP54_RS13920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12316"
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="WP_090170729.1"
                     /transl_table=11
                     /translation="MEKGIVQVYYGTGQGKSAAALGLAVRNASQGRTTTIIQFLKSETN
                     TEYLSKLEPEIKLFRFERSKESFSDLTDEQKQEEILNIQNGLNYAKKVLGTGESDLVIL
                     DEILGVVDEGIVSEQDILCALEGRSYSTNVILTGLNITRGIFEIADSVLNLKPEK"
     gene            complement(4433..6265)
                     /gene="typA"
                     /locus_tag="BLP54_RS13925"
                     /old_locus_tag="SAMN05421493_12317"
     CDS             complement(4433..6265)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="typA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548730.1"
                     /locus_tag="BLP54_RS13925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12317"
                     /product="translational GTPase TypA"
                     /protein_id="WP_090170732.1"
                     /transl_table=11
                     /translation="MSIQSREDIRNIAIIAHVDHGKTTLVDELLKQSGVFRENQEVAER
                     VMDSNDIERERGITILSKNTAVYYKNTKINIIDTPGHADFGGEVERVLKMVNGVVLVVD
                     AFEGAMPQTKFVLMKALDLDLPVIVCINKIDRPEARPDEVIDEVLELFMDLDASDEQLD
                     CPFIYASAKEGFAIRDLNEEHKDMTALFETIVDYIPAPKGDPEAPTQVLISTIDYNEYV
                     GRIGIGKVENGSIKVNQDAIVVNAHDESKNNKVRISKLFEYDGLNKVDVTEAQIGSIVA
                     ISGISDIHIGDTICAPDAPNPIPFQKISEPTISMNFIVNDSPLAGQEGKFVTSRHIRER
                     LMKELNTDVSLRVEDTDSPDSLKVSGRGELHLSVLIENMRREGFEFAVSKAEVLYKEDE
                     KGHKLEPMERAYVDVPDEFTGAVIEKLSQRKGELQNMTPIAGGYTRIEFKIPSRGLIGY
                     RGEFMTDTKGNGIINTIFDGYELYKGDISYRKLGSLIAFETGESVTYGLFSAQDRGTLF
                     IGPGEKVYSGMVIGQCSRAEDVELNVCKKKHLTNTRSSSADEALTLVPPRVLSLEQALD
                     FIDVDELLEVTPESLRIRKRILDPTLRKRASFKK"
     gene            complement(6367..7656)
                     /gene="serS"
                     /locus_tag="BLP54_RS13930"
                     /old_locus_tag="SAMN05421493_12318"
     CDS             complement(6367..7656)
                     /EC_number="6.1.1.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006855678.1"
                     /locus_tag="BLP54_RS13930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12318"
                     /product="serine--tRNA ligase"
                     /protein_id="WP_090170735.1"
                     /transl_table=11
                     /translation="MIDIKFLRENPDAVKENIKKKFQEHKLGLVDEVIELDDKRRAAQQ
                     EADDLRAQMNKASKEIGALMGQGKKEEAEKAKAEVAELKQRIKDLEPVEKELADKVEEI
                     MMKIPNIIDPSVPIGPDDSCNVEIEKFGEPVVPDFEIPYHTDIMERFNGIDLDAAGKVA
                     GNGFYYLMGDIARLHSAVISYARDFMIDRGFTYCIPPFMIRSNVVTGVMSFEEMDAMMY
                     KIEGEDLYLIGTSEHSMIGKFIDTLNDEANLPYTLTSYSPCFRKEKGAHGIEERGVYRI
                     HQFEKQEMIVVCKPEESKKYYDILWNNTVDLFRSLDIPVRTLECCSGDLADLKVKSCDV
                     GAWSPRQKKYFEVGSCSNLGDAQARRLKIRVKDENGNKYFAHTLNNTVVAPPRMLIAFL
                     ENNLREDGSVAIPEALRPYMGGKSELTPTK"
     gene            complement(7679..9949)
                     /gene="secD"
                     /locus_tag="BLP54_RS13935"
                     /old_locus_tag="SAMN05421493_12319"
     CDS             complement(7679..9949)
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016279941.1"
                     /locus_tag="BLP54_RS13935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12319"
                     /product="protein translocase subunit SecD"
                     /protein_id="WP_090170738.1"
                     /transl_table=11
                     /translation="MKRLKKGQGIAWLVAFVVILGLLGYYAATVITGTIKENDDSLKLG
                     LDLDGGVSITYEAVGDKPTDEQMADTILKLQQRIENDLGEESATTEANVYRVGDDRITV
                     EIPGVSDANALLEELGTPGTLYFIAQKDSEGNENYSYGENGYELNYDIETLTENGSVIC
                     TGKEVTAAQGRAEQDKTTSATKYVVTLQFNDEGTKAFGDATTVAAVAGETIGIYYDGKF
                     VSVPKVNEAITTGNCEISGMSSMDEAEKLASYIRIGGLDIELQELESQVVGAQLGADAL
                     RTSLIAAGIGLGLVMIFLIVMYLVPGLVSSLALALYTAMLIGILKAFDITLTLPGIAGM
                     ILSIGMAVDANVIVFARVREEIKNGRPVVSSIEAGFSKALSAILDGNITTLIAAAVLGI
                     LGSGSVKGFAITLALGVVLSMFTALVITRILINSFYALGVRDAKFYGKAKEPSKFDFVG
                     KKAIFITISVAIIAAGFITMGAMKAKTGSGLNYSLEFLGGTSTTVDFNETYSLADLDAK
                     VVPQIASTIGVSEGSIQTTTVDGSNQAIFKTRNLTLEERESLNEMFESQFQVKDTSITQ
                     QTIGSTISGEMRSQSTIAVLVAVLCMLVYIWFRFKDIRFASSAIIALVHDVLVVLALYA
                     FARISVGAAFIACMLTVIGYSVNDTIVVFDRIRENHKAVRTENAETLKALCNESLAQTL
                     SRSISTSITTAIMVLMLLILGVSSIREFALPLLAGVIAGTYSSIFIATQLWYILKLKFA
                     SKN"
     gene            complement(10001..11386)
                     /gene="scfB"
                     /locus_tag="BLP54_RS13940"
                     /old_locus_tag="SAMN05421493_12320"
     CDS             complement(10001..11386)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012741874.1"
                     /locus_tag="BLP54_RS13940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12320"
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_090170740.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.1e-32,
                     bitscore: 103.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4e-73, bitscore:
                     237.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.1e-15, bitscore: 47.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.2e-14, bitscore: 44.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.2e-18, bitscore:
                     57.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQFKNNGYNIVIDINSGAIHVVDEVTYDFLGLWQEQGKDAALS
                     QMKISHPEVSEAELTEIQSEIEQLIADGALFTEDNYEPRIADFTARPAVVKALCLHITH
                     DCNLACKYCFAEEGEYHTGKRELMTYEVGKQALDFLVANSGSRRNLEVDFFGGEPLMNW
                     QVVKDLVAYGRSLEKEHNKNFRFTLTTNGVLLNDEIQEFANKEMANVVLSCDGRPEIHD
                     LMRPFKKGAGSYDIVMPKFKKLADSRNQDRYYIRGTFTRNNLDFSKDVIHLANEGFKQI
                     SVEPVVAQETDDYALREEDLPKLFEEYDSLCAEMMRRQGTDKDFNFFHFMIDLEGGPCV
                     YKRLSGCGSGTEYMAVTPTGELYPCHQFVGNTDFCLGDVWGGVKNKEVVNQFKHCNVYA
                     KEECKNCFARFYCSGGCAANAFNFTGSILGNYHVGCELQKKRVECAIALKVHNAEINET
                     KEA"
     aSDomain        complement(11084..11386)
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BLP54_RS13940_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="7.90E-33"
                     /identifier="RREFam024.1"
                     /label="BLP54_RS13940"
                     /locus_tag="BLP54_RS13940"
                     /protein_end="101"
                     /protein_start="0"
                     /score="103.6"
                     /tool="antismash"
                     /translation="MIHQFKNNGYNIVIDINSGAIHVVDEVTYDFLGLWQEQGKDAALS
                     QMKISHPEVSEAELTEIQSEIEQLIADGALFTEDNYEPRIADFTARPAVVKALCLH"
     gene            complement(11485..11628)
                     /gene="scfA"
                     /locus_tag="BLP54_RS13945"
                     /old_locus_tag="SAMN05421493_12321"
     CDS             complement(11485..11628)
                     /codon_start=1
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004064898.1"
                     /locus_tag="BLP54_RS13945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12321"
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_015548727.1"
                     /sec_met_domain="TIGR03973 (E-value: 2.6e-27, bitscore:
                     85.9, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2e-27, bitscore: 86.3,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTARLQNTVKEGGCGECQTSCQSACKTSCTVGNQSCEH
                     SK"
     gene            complement(11724..12896)
                     /locus_tag="BLP54_RS13950"
                     /old_locus_tag="SAMN05421493_12322"
     CDS             complement(11724..12896)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017509.4"
                     /locus_tag="BLP54_RS13950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12322"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_090170743.1"
                     /transl_table=11
                     /translation="MKNRFLALLLVGTLAFSFTACGSKEEDKAETKTEQSADTEKKSDA
                     KPIEYDVDELVTLGDYKGLDITLDGEYEYTDKGFDEYVSKTISEAAIYVEDSSAKEIKE
                     DSIVNVDYVGSQDGVAFDGGSAEDQLIDVGNNSSATGGGYIEGFTAGLVGHKVGEEVAY
                     EVKFPDDYGNADLAGQTVIFTFQVNYIAKAIDSKKALTDDIVSDKFGYDTVDAYIDSLK
                     DKYTASLENNLKSDKQTTVLNAVLNNSKVSKVPEDLLQARVDMYLNVYEKQYQSYGTTA
                     KEYFESMGQDYDAYVESMKTSIQESTETELILEAIAKAEGIEIDEDGYKEFIQGILSSS
                     GASDETSFYEVYDVDGYTGERYFRQAYLTQKALDFCIDNASYTGAPAVAE"
     gene            complement(12970..14484)
                     /gene="malQ"
                     /locus_tag="BLP54_RS13955"
                     /old_locus_tag="SAMN05421493_12323"
     CDS             complement(12970..14484)
                     /EC_number="2.4.1.25"
                     /GO_function="GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="malQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548714.1"
                     /locus_tag="BLP54_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12323"
                     /product="4-alpha-glucanotransferase"
                     /protein_id="WP_090170746.1"
                     /transl_table=11
                     /translation="MKRSSGILLPISSLPSPYGIGTFGKAAYDFADFLKAAGQKYWQVL
                     PLGPTSYGDSPYQSFSTFAGNPYFIDLEMLIEEGLLTKEEVEAENWGTNPRYVDYGQIY
                     ESRFKILEKAKERGYKDSLGEISHFRKKNAWVENYALFMAIKKHFGQLSWQEWPEEDIR
                     LHEAKAVEKYTKKLEEDIEFFVYIQYLFFKQWAKLKTYINSLGIEVIGDLPIYVALDSC
                     DVWAEPEFFSLDEDNYPVEVAGVPPDYFSEDGQFWGNPCYDWNALKKDGYKWWIRRIEG
                     AAKLYDVLRIDHFRGFDEYWAVPAKEKTAKNGKWKKGPGMDLVGLLTKTFPSIEFIAED
                     LGEPSPTVVKLLQDSGWPGMKVLEFAFDSGEPNNYQPHTYDKNCICYTGTHDNATIMGW
                     YEEADKKDKEYASKYLGISKAEGFNWGMIRGGMSSVSVLFVAQMQDFLGLGKYNRINVP
                     GTESGNWQWRLLAKEPTPELAKKIFDMSVMYDRTKKPPKAKKKARK"
     gene            complement(14504..15346)
                     /locus_tag="BLP54_RS13960"
                     /old_locus_tag="SAMN05421493_12324"
     CDS             complement(14504..15346)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548713.1"
                     /locus_tag="BLP54_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12324"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_090170748.1"
                     /transl_table=11
                     /translation="MKAKEQVARLIVFIVLCLLAVCWIYPVFMILINSLKGDAFISTNS
                     VFTLPDAKSFVGFSNYLDALSSKGFAAAFGYSLVITVSSAVLILICTSMCAWYITRVHG
                     ILSKVCYALFVFSMVVPFQMLMFTLASTADRMDLDTPYNICIIYLGFGAGLAVFMFTGF
                     MKSIPLEIEEAAMIDGCNPIQTFFQIVLPILKPTLISVAILETMWLWNDYLLPYLVLDR
                     KKYMTIPILIQYFRGSYGHVEMGPMMACIMMTVLPIIIMYICLQKYIIKGVIAGAVKG"
     gene            complement(15346..16197)
                     /locus_tag="BLP54_RS13965"
                     /old_locus_tag="SAMN05421493_12325"
     CDS             complement(15346..16197)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548712.1"
                     /locus_tag="BLP54_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12325"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_090170751.1"
                     /transl_table=11
                     /translation="MEKAIRKYWPVFVLPTLAAFSVGFIYPFVQGLYLSFCKFTTIKKS
                     TFIGFGNYAYAITDADFWHSFWFTALFTVVSTVLINVIAFAIALALTNKIKGSNFFRTV
                     FFMPNLIGGIVLGYIWQILINCVLSLLEKPLLALNATYGFIGLTILMCWQQIGYMMIIY
                     IAGLQSIPDDYIEAAKIDGATTGQILFKIKIPNVMPSITICSFLTITNGFKLFDQNLAL
                     TGGEPAHASEMLALNIYNTFYSRTGPQWKGYGQAKAVIFCIMVILISMIQLKITKSKEV
                     QQ"
     gene            complement(16387..17697)
                     /locus_tag="BLP54_RS13970"
                     /old_locus_tag="SAMN05421493_12326"
     CDS             complement(16387..17697)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015548711.1"
                     /locus_tag="BLP54_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12326"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_090170755.1"
                     /transl_table=11
                     /translation="MKRKRVLALGLIAMMAAATFAGCGSSASGDSAGDSASADGASGKV
                     YYLNFKPEADEAWQEIAKQYTEETGVPVTVITAASGTYEETLSSEIVKDEAPTLFQVNG
                     PVGLANWADYCYDLKGSSLYNELTSDSFALYNDDAVAGIAYVIESYGIITNTKLLEQAG
                     YTLEDIQSFDDLKKVAEDITARKDELGFAAFTSSGMDGSSDWRFKTHLANLPIYFEYQE
                     KGIDSTDAIEGKYLDNYKAIWDLYINNATCKPGDLAGKTGDDAENEFADRQAVFYQNGS
                     WEYANLTKKGMTDDELAMIPIYVGAGDEKNQGLCTGTENYWCVNSEASEEDIQATIDFL
                     TWMVTSDAGTKMLSEQIGVIPFKKAADTTNLFVLNDRAYTEAGKTPVSWNFTTMPSEEW
                     KNGVGSALTAYAAGTGSWDDVVSAFVDGWASEYAASH"
     gene            complement(17776..18786)
                     /locus_tag="BLP54_RS13975"
                     /old_locus_tag="SAMN05421493_12327"
     CDS             complement(17776..18786)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="BLP54_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12327"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_176754578.1"
                     /transl_table=11
                     /translation="MTIKDIAKLAGVSVSTVSRVLNDHPDVSESAKEKVLAVVNEYNYI
                     PNTSARDLGKSSSDNIGLVVRGISNPFYTKIITEISDKIEKAGYTMVMQQIGTSDDEIL
                     AAARMERDKRLLGLIFLGGRLNYTKEQVSAINVPFVCCTFNNQYGTLDKSDYSSVCIDD
                     NQAAYEAVEYLYKEGHRRIAVLLSGPDDGSVSQVRFAGYERALNDFGIELDENLIIPIN
                     SYNIADAYEGMKAWLKKNNDFSAVFAISDNMAMGAMKALREAGKSIPKDVAVIGIDGIE
                     ASEYMNPVLSTLCQPMEEMGDEAVKLVVDIIKGKKNHKHILLSTTLREGESFREV"
     misc_feature    18965..18979
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(18983..20572)
                     /locus_tag="BLP54_RS13980"
                     /old_locus_tag="SAMN05421493_12328"
     CDS             complement(18983..20572)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040163.3"
                     /locus_tag="BLP54_RS13980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_12328"
                     /product="DUF5722 domain-containing protein"
                     /protein_id="WP_090170761.1"
                     /transl_table=11
                     /translation="MKVFKKIASGVIALALIVTMFAGAPSLTAEAKGTSGVAIGGAVIE
                     GGNVVVAASGQTASEDGIYHLIASDPNQAGNTGKEVAQAPVAAAANFTFPLNKNSAESV
                     LFKKFTVCVMKGGALTAASNSMYITNPEACGSRAIARMDNGKKGILTDASTDNLGMRTL
                     ADLGVKQATVSLPLSKISGGSGVPYVYNGKTYNFDTRYIAAFDNYLGRLNAQGVQVTMI
                     LLVDQASQGEFISPYALNGLGKHNYYGLNATTTEGIELLAAAGSFIASRWMSHSYFGMN
                     ARVDNFIIGNEVNAWNEWNYMSCGGNLSLYAQEYANAFRVLFNAIKSENANANVYICTD
                     HQWAVNTKNTHGAKAFITQFNNYIRAQGNIDWRLAFHAYDYPLKSATPWVPTANVQRNQ
                     NTKFVSIYNIDVVTDFLSQPELLSPSGAVRTVKLSEQGYTSSQGEEIQCAAITFAMLVV
                     NNNSHIDGFILSREKDDPYIEVPQGLAFGLMRDNNTHKLSYDYYKHAGEPEYTAKASEM
                     IGLDLNSLIAPR"
ORIGIN
        1 aaatccaaat atcgataacc atcttcaagc tgctgtgcaa ttgatgtctc ctgacatctc
       61 ataacatagc ccaacgcaac attctgagcg cctgagttgt gagctcctgg tatggtaatc
      121 tgtgaaatat aggtatcatc ggatatgttc tccatccagc tggcagtgtc cgaatattcc
      181 ttcgtcatat ccacactgaa ctccgaggca gtatcatcat cgctgacaaa cagaataaca
      241 agaataccca cgatgattgc aatcattact ccacaaataa ttctaaaaag ccgtccctta
      301 tccataagca cgtcccccgt atttaggctt taacattatt ctatataaat atattaccat
      361 tctttagtga caaagtcttt caaaatcggt actattgaat agaaatatat ctgatttatg
      421 gaggataact atgatagata gaggcagact cttatcttta ggatattata aaaaagctcc
      481 ctcttttaca gggagcgata aaaataaatg ttataaaatt gagcgcttcc gcgaggaaga
      541 ttctgaggta gatatgttca aagccacaat ctggcctggc ccattcagct cagaaaacac
      601 tcctgaggaa tccaagcaat ccaagcttgc tccttttacc gaagacggct tacaggagct
      661 ggtagattgg atgaacagtc tggatatcta aactgtcttg gatgctttct tattttcgta
      721 cattgattcg tctgcgcgct tcacaagtgc gcggaagtct ttgtcgagct cagagtcaaa
      781 catcgcagct ccgatggcaa ctccaattga gtactggtac tttccttcaa gattcgcagt
      841 ataaatcttt gtcataaaga gcttctttaa tcgctccata ttaactgctt tgcttgaagg
      901 gatgatacaa cagaactcat ctccacctgt acggtagcaa gttccatatc ttccaaatac
      961 gccgttgaaa atttctgcca caagggtaat atactcatca ccagcctcgt gaccataagt
     1021 atcattacat gctttaagac cattggcatc tgcaacaaca gcgattatgc catcaagctt
     1081 tctatccgac tcagcctgac tttcaaatgc atttctatta taaaggcctg tcatactatc
     1141 tgtaagagca aatatctcaa gctgtctagc acgacgtccc ttttcaataa gttcgttagt
     1201 tcctcgaatc aaatcccatg caaggagtaa tacgaatata agaaccatgt aacgaccgag
     1261 tctgtcagca tcaccaatta ttctgtaata attgataaca tctacaacca ttgcaataag
     1321 gaataaagat acaccgatag tacaaattat tacctgacgt gaaaaatcac ggtgtaaaag
     1381 ctgtaggata atagcaccta caacatatgc cacggcaacg gttatcataa gctgtacaaa
     1441 catcagattt tctctaaatt ctcgtatctt aaggaaatgc atagatgtaa cagtaataaa
     1501 ttccaccatt gatgcccaaa gaattatttt ctttataatc tttccgttaa ttcctaagta
     1561 agaatcaaag aaaagaacaa atggcggaac tgaaagcatt aagcatatat aaggaattat
     1621 cgaatcaaat atcctatttt cggataccaa agtccatgca atagtttcat ttgttgacca
     1681 cacgccaata aacaacgaga aataaccaag ataaataagg tcttttccta aattaagtcg
     1741 cttattcatg aaaatatagt atgcaaatag tgtcaaacta aaaataacta taaagatact
     1801 ggctataagc ctaggaatag agtcacgaag aaactcagaa tatatctgat acgtatttcc
     1861 tatgtaaaac tcaggtacct tttcgctaac aatatcataa gctggagtta atataactgc
     1921 cacattttgc attttctcat ttatagaaac aaaattgtat ttagctcctg gtgtagaacc
     1981 ccaaaaaccg ccagtttttg taaatgagta aatctcatgc ccggcattat atacggtaac
     2041 tgactgatgc gcggtaaaaa acaccaagcc agagtactga ctatcatagc tagataaatc
     2101 gataaagtat tccttagagc catcttctaa aagcgcaact tgatatggct caattctaga
     2161 ggtagacgtc tcatcttttt ttacatctct tgtcatcatg taacaaatga taagacccac
     2221 tatcgctata acaagcatca cattattcaa ttttctatga aaactaaata aattctttcc
     2281 ttgcttcata aaaaaaccaa tccagacatt tttcaaacat cattacaaaa ataaatattt
     2341 tcataaaaac ttcacgtttt ataacgatta tacaatctaa atgttggatt ggcaactaaa
     2401 atattatcta ataaagttat agatatgtgg atataatgta tctttttcca caatataact
     2461 gctatgattt tccccagaaa ggatttttaa tactgaattg gggatacttt gagctatctt
     2521 ttctgtttct ttttgcttca cgcagtcatc ttctccagca aatatcattg ctggaacagt
     2581 tatattcttc aaatcctctg gatttatatc aggttcctga agcatcatca aagttctagg
     2641 atcattatac tttttataat ccttcttcat ttcccttaaa tctctgtgat gaagccctgc
     2701 cggactaaga tttgcaccgc agcacactat tccggataac aactcacttg cctgcatggc
     2761 aaccaataaa gaaataatac cgccatctga atatccaatg agatatggct tttcaatatc
     2821 taatccttta attaagttaa ttacatcatt cgccatatca ctataatgat attccttcgg
     2881 cgtggcactc tcaccatgac ctcttgaatc catagcataa acgacattgt atttgctgag
     2941 acgctctacc aatggatcga agatatgatg atcttctcta tttccatgta tgagaataac
     3001 cggggtgccc tgatccccgg tcctttcata gcatatgatt tgtgagttaa gttgaatata
     3061 catatacgcc ctcggctata attatttttc tgcgattact tctttcatat cgtaaaggcc
     3121 agctgactta ccagcaagga acttagcagc ttctactgct ccctttgcaa atacactctt
     3181 tgaatatgct gtatgcttga ttgtaataac ctcatcaagt cctgcaaaga ttacctcgtg
     3241 ctcgcctaca atatttccac cacgaactgc agaaatacca atttcattct ttggtctctt
     3301 ctctcttctg tcagctctgg catagcaata ctcatacttt tcatctaaag catcgttgca
     3361 ggcatctgca agagcgagtg ctgttccact aggtgcatca agcttttgat tgtgatgctt
     3421 ctcaacaatt tcaatatcaa aaccagcatc agcaaaaatc tgagtagcct tcttacataa
     3481 atcaaataat gtatttattc ctaatgacat gttagcagag cgaaggatag caaccttttt
     3541 gctagctgca tctacatgtg caagctgatt atcatcaagt cctgtagtgc aaagaacaac
     3601 tggctttcca gtcttctcac aaacatcaag caaaccatct actgcagctg ctgtagagaa
     3661 atcaattaca acatcgtaat ctacatcaac ctcttcaaga gaatcgaata caggataatc
     3721 attatctatg cctttgaact tatctactcc tgcaacaata gtagccgctg aatcattcat
     3781 gcataaatct gtgataactc ttcccatgtg tccgttgcaa ccgtgcataa caatttttgt
     3841 cattattctt acctcttttt cgtacatgcc aataatatgt tttattttat tatataaaag
     3901 aactgccata gagaccataa aaagtccatg gcagtcctat gaaattactt ttcaggttta
     3961 agatttaaaa cactgtcagc aatttcaaat attcctcttg ttatatttaa tcctgtcaaa
     4021 ataacattag tcgaatatga acgaccttcc aaagcgcata aaatatcctg ctctgaaacg
     4081 attccttcat caactacacc aagaatctca tcaagaataa ctaaatcact ttcgcctgtg
     4141 ccgagaacct ttttagcata attaaggcca ttttgaatat tcaaaatctc ctcctgcttc
     4201 tgctcatctg taagatcaga aaagctttcc tttgagcgct caaatctaaa aagcttaatc
     4261 tctggctcaa gcttacttaa atactcagta tttgtctcag atttaaggaa ctggataatt
     4321 gtcgtggtgc gcccctgaga tgcattacgc acagcaaggc ctagtgctgc tgccgacttt
     4381 ccctgtcctg ttccataata tacttgaaca attccctttt ccataagtct ccttatttct
     4441 taaagctagc tctctttcta agtgttggat caagaattct ctttctaatt ctaagagatt
     4501 ctggagtaac ctccaaaagc tcatctacat caatgaaatc aagtgcctgc tcaaggctaa
     4561 gaactcttgg tggaacaagt gtaagcgcct catctgctga agatgaacga gtatttgtaa
     4621 gatgtttttt cttacataca ttaagctcaa catcctctgc acgagagcac tggccaataa
     4681 ccataccaga ataaaccttc tcacctggtc cgatgaaaag tgtaccacgg tcctgtgctg
     4741 agaaaagtcc gtatgtaact gactcacctg tctcgaaggc aataagactt ccaagcttac
     4801 gataagaaat atcgcccttg taaagctcat aaccatcaaa aattgtattg attataccat
     4861 ttccctttgt atctgtcatg aattctccac gatatccgat aagaccacgt gaaggaatct
     4921 taaattcgat acgagtatat ccacctgcga taggtgtcat gttctgaagc tcaccctttc
     4981 tctgagaaag cttctcgata actgctcctg taaactcgtc tggaacatct acgtaagcac
     5041 gctccattgg ttcgagcttg tgtccctttt catcttcctt ataaagaacc tcagcctttg
     5101 atacagcaaa ctcaaaacct tcgcgacgca tgttctcgat aagaactgaa aggtgaagct
     5161 caccacgacc agaaacttta agtgaatctg gtgaatctgt atcctctaca cgaagtgaaa
     5221 cgtcggtgtt aagctccttc ataagacgct cacgaatgtg acgtgaagta acgaacttac
     5281 cttcctgacc agcaagtggg ctatcattta caatgaagtt cattgaaata gtaggctcag
     5341 aaatcttctg gaatggaatt ggatttggag cgtctggtgc acaaattgta tctccaatgt
     5401 gaatatctga aataccagaa atagcaacaa ttgaaccaat ctgagcctca gtaacgtcta
     5461 ctttattaag tccatcatac tcaaaaagct ttgagatacg aaccttatta ttcttgctct
     5521 catcgtgagc attaactacg atagcatcct ggttaacctt gatcgaacca ttctctacct
     5581 taccgatacc gatacgtcca acgtactcgt tgtaatcgat tgtagagata agtacctgtg
     5641 taggagcctc tgggtcaccc tttggagctg gaatgtaatc tacgatagtc tcaaagaggg
     5701 ctgtcatatc cttatgctct tcgttaagat ctctgatagc gaaaccttcc ttagcagaag
     5761 cataaataaa tggacaatca agctgctcat ctgaagcatc aagatccatg aaaagctcta
     5821 atacttcatc gataacctcg tctggacgag cctctggtct atcaatctta ttgatacata
     5881 cgataactgg taaatcaaga tcaagtgcct tcataagaac gaacttagtc tgtggcattg
     5941 caccctcaaa tgcatctact acaagtacaa caccgtttac catcttaagt acacgctcta
     6001 cctcaccacc gaaatcagca tgccctggtg tatcgatgat gttaatcttt gtgttcttat
     6061 aatatactgc tgtgttcttt gaaagaatag tgataccacg ctcacgctca atatcatttg
     6121 agtccatgac acgctcagca acttcctgat tctctctaaa tacacctgac tgctttaaaa
     6181 gctcatctac aagtgtagtc ttaccatgat caacgtgtgc gatgatggca atatttctaa
     6241 tatcttctct actctgaatt gacataaatt tctcttttct taattcttac aataaactac
     6301 attgtaaaaa cctaccccta aatatcaagc agttcccaaa aatgagaact gcttgatttt
     6361 acattgttat ttcgttggtg tcaactcact ctttccaccc atgtatggac ggagtgcttc
     6421 tgggatagca actgagccat cttcacgtaa gttattctca aggaatgcga taagcatacg
     6481 tggtggagca actactgtat tgttaagtgt atgagcgaag tacttattac cgttctcatc
     6541 cttaacacga atcttaagac gtctagcctg agcatcacca aggttagagc aagaacctac
     6601 ctcaaaatac ttcttctgac gtggtgacca tgcccctacg tcacaagact taaccttaag
     6661 atctgccaaa tctcctgaac agcactcaag tgtacgaaca ggaatatcta agctgcggaa
     6721 taaatcaact gtgttgttcc aaaggatatc atagtacttc tttgactcct ctggcttaca
     6781 aactacgatc atctcctgct tctcgaactg gtggatacgg taaacaccac gctcttcaat
     6841 accgtgtgca cccttctcct tacggaagca tgggctatag cttgtaagtg tatatggaag
     6901 attagcttcg tcattgagtg tatcaatgaa cttaccaatc atagagtgct ctgatgtacc
     6961 gatgaggtaa agatcctcgc cctcgatttt gtacatcatg gcatccatct cttcgaatga
     7021 cataacacca gttactacgt ttgaacgaat catgaaaggt gggatgcaat atgtaaatcc
     7081 tctatcgatc atgaaatcac gagcatatga gataactgct gagtgaagac gagcaatgtc
     7141 tcccatgagg taatagaagc cgttaccagc aaccttacca gcagcatcca aatcgatacc
     7201 attgaatctc tccatgatat ctgtgtgata aggaatctca aaatcaggta caactggctc
     7261 accaaacttt tcgatttcta cgttgcagga atcatctgga ccaattggaa ctgaagggtc
     7321 gataatgtta ggaatcttca tcatgatttc ctcaacctta tcagcaagct ccttctcaac
     7381 tggctctaag tccttaatgc gctgcttgag ctcagctacc tcagccttag ccttctcagc
     7441 ctcttccttc ttgccctgac ccataagagc accaatttcc tttgatgcct tattcatctg
     7501 agcacggagg tcgtcagctt cctgctgagc agcacgtctc ttgtcatcaa gctcgatgac
     7561 ctcgtctacg aggccaagct tgtgctcctg aaacttcttt ttaatatttt ccttaactgc
     7621 gtctggattc tcacgtaaaa acttaatgtc tatcatgttt tttctcctag ttctaatctt
     7681 aattctttga agcaaactta agcttaagga tgtaccaaag ctgtgttgcg ataaagattg
     7741 atgaatatgt accagcaatt acaccagcaa gaagtggtaa tgcgaactct ctgattgatg
     7801 aaacaccaag gataagaagc ataagtacca tgatagctgt tgtgattgat gttgaaatag
     7861 aacgtgaaag tgtctgagca agtgactcgt tacaaagtgc cttaagtgtc tcagcatttt
     7921 ctgttctaac tgccttgtgg ttctcacgga tacggtcgaa tacgacgatt gtatcgttga
     7981 ctgagtaacc gataactgta agcatacatg cgatgaatgc agcgcctact gaaattcttg
     8041 cgaatgcata aagtgcaagt actacaagaa cgtcatgtac aagggcgatg attgctgaag
     8101 aagcaaatct gatgtccttg aatctgaacc aaatatatac gagcatgcag agaactgcaa
     8161 caagtactgc gattgtagac tggctacgca tctctcctga gattgtagaa ccaattgtct
     8221 gctgagttat tgaagtgtcc ttaacctgga actggctttc aaacatctca tttaatgact
     8281 ctctctcttc aagagtaaga tttcttgtct tgaagattgc ctggttgctt ccatctactg
     8341 ttgtagtctg gatgcttccc tcgctaacac cgattgtgct tgcaatctga ggaactacct
     8401 ttgcatccaa atctgcaagt gaatatgtct cgttgaaatc aactgttgtt gatgtaccac
     8461 caaggaactc aagtgagtag ttaagacctg aaccagtctt agccttcata gctcccattg
     8521 tgataaaacc agctgcaata attgcaactg aaattgtaat gaagattgcc ttcttgccaa
     8581 cgaagtcgaa ctttgaaggc tccttagcct ttccatagaa cttagcatca cgaacgccaa
     8641 gtgcatagaa agaattaata agaattcttg taataacaag agctgtaaac attgataaaa
     8701 caacaccgag tgcaagagta attgcgaatc cctttacaga acctgaacca aggataccaa
     8761 gtactgctgc tgcgataagt gttgtgatgt taccatcaag gattgctgaa agtgccttag
     8821 agaaaccagc ctcaatagat gaaactactg gacgaccatt cttgatttcc tcacgtacac
     8881 gagcgaatac gataacgtta gcatcaaccg ccataccgat tgaaagaatc atacctgcga
     8941 taccaggaag tgtaagtgta atatcaaatg ccttaagaat gccgataagc attgctgtgt
     9001 aaagagcaag tgcaagtgat gaaacaagac caggtacaag gtacataaca ataaggaata
     9061 tcattacgag accaagacca atacctgctg cgataagtga tgttctaaga gcatcagcac
     9121 caagctgagc acctacaacc tgtgactcta actcctgaag ctcgatatca agaccaccga
     9181 tacggatgta agaagcaagc ttttctgctt catccataga agacatacca gaaatctcac
     9241 agttacctgt tgtgattgct tcgtttacct ttggaactga aacgaactta ccatcatagt
     9301 agataccaat tgtctcgcct gcaactgctg ctactgttgt agcatcaccg aaagcctttg
     9361 ttccttcgtc gttgaactga agtgttacaa cgtactttgt agcgctagta gtcttatcct
     9421 gctcggctct tccctgagct gctgtaactt ctttacctgt acaaataact gaaccatttt
     9481 ctgtgagtgt ctcgatatcg tagttgagct cgtatccgtt ctcaccgtag ctgtagttct
     9541 catttccttc gctatccttc tgagcgatga agtaaagtgt accaggagta cctaactcct
     9601 ccaataatgc atttgcatct gaaactccag gaatctcaac tgtgattctg tcatcgccta
     9661 cgcgataaac atttgcttct gtagttgcgc tttcctcgcc aaggtcattt tcaatacgct
     9721 gctggagctt aaggattgtg tctgccatct gctcatctgt aggcttgtct ccaactgctt
     9781 catatgtaat gctgacacct ccatcaaggt cgagaccaag ctttaagctg tcatcattct
     9841 ctttaattgt gcctgtgata actgttgctg cgtagtatcc aagtaaacca agaataacta
     9901 caaatgcaac gagccaggca atcccctgtc ctttttttaa acgtttcatt atttattctc
     9961 ctatcttgta atttataact gctgtgcagt ctaaagagga ctatgcctct tttgtttcgt
    10021 taatctctgc attgtgcacc tttaatgcaa ttgcacattc aacacgcttc ttctgaagct
    10081 cacatcctac atggtaatta ccaagaatgc ttcctgtgaa gttaaatgca tttgctgcac
    10141 atccgccgct gcagtagaat cttgcaaaac aattcttgca ttcttctttt gcgtaaacat
    10201 tgcaatgctt gaactgattt acaacttctt tgttcttcac cccgccccat acgtcaccga
    10261 gacagaaatc tgtgtttcca acgaactgat gacatggata aagctcacct gtaggtgtaa
    10321 ctgccatgta ctctgttcct gaaccacagc ctgaaagacg cttgtaaacg caagggcctc
    10381 cctccaaatc aatcatgaag tggaagaaat tgaaatcctt gtctgtaccc tggcgacgca
    10441 tcatctcagc acaaagtgaa tcatactctt caaagagctt tggtaaatcc tcctcacgaa
    10501 gagcataatc atctgtttcc tgtgcaacta ctggctcaac ggaaatctgc ttgaagcctt
    10561 cattagcaag atgaataaca tccttagaaa aatcaagatt gttacgtgtg aatgtaccac
    10621 ggatataata tctgtcctga ttacgtgaat cagcaagctt tttgaatttt ggcattacga
    10681 tatcgtagct gcctgctccc ttcttgaatg ggcgcataag atcatgaatc tctggacgac
    10741 catcgcagct aagtactacg ttagccatct ccttatttgc aaattcctga atctcgtcat
    10801 ttaacaatac accgttagtg gtgagtgtaa atctaaagtt tttattgtgt tccttctcaa
    10861 gagaacgacc gtaggcaact aaatccttaa ctacctgcca gttcataagt ggctcgccac
    10921 cgaagaaatc aacctcaagg tttcttctgc tgcctgaatt agcaacgagg aaatcaagag
    10981 cctgcttacc aacctcgtag gtcataagct cgcgctttcc tgtgtgatat tctccctctt
    11041 ctgcgaagca gtacttgcag gcaaggttgc aatcgtgggt tatatgtaag caaagagcct
    11101 ttacaactgc aggacgtgct gtaaaatcag caatccttgg ctcgtaattg tcttctgtaa
    11161 ataatgcgcc atcagcaata agctgctcaa tttctgactg aatctctgta agctctgcct
    11221 cagaaacctc aggatggctt atcttcatct gtgaaagcgc tgcatccttt ccctgctcct
    11281 gccaaagacc aagaaaatcg tatgtgactt catctactac gtggatggca ccgctattga
    11341 tatcaataac aatgttgtaa ccgttgtttt taaactggtg aatcactaaa aaaatgtcct
    11401 ttcataaacg cacaatagac cgttccccac caaaactggt gaggtccggt ctgcgttaaa
    11461 tattacttct ttaaaaatga gctattactt agagtgctca cagctctggt ttccaactgt
    11521 gcaagaagtc ttgcaagctg actggcatga tgtctggcac tcgccacatc cgccttcctt
    11581 tacagtgttc tgtaatcttg cagtatttaa tgttttgatg tgttccataa tgaatatctc
    11641 cttttcttta aacagctact actcatagta accctaagat taattgatta tactataaat
    11701 cggctaaaat ataaagcttt ttcctattct gctaccgcag gtgctcctgt gtaacttgca
    11761 ttatcaatac agaaatcaag cgccttctgt gtgagatatg cctgacggaa atatctctca
    11821 cctgtatagc cgtctacgtc atatacttca tagaagcttg tctcgtctga tgctcctgaa
    11881 gatgaaagga tgccctggat gaactcctta tatccatcct catcgatttc gatgccctca
    11941 gcctttgcaa tagcttcaag gatgagctct gtctctgtag actcctgaat gcttgtcttc
    12001 atgctttcaa cataagcatc gtaatcctgt cccatagact caaaatattc ttttgcagta
    12061 gtgccatatg actgatactg cttttcatat acattaaggt acatgtctac tcttgcctga
    12121 agaagatcct caggaacctt tgatacctta ctgttgttta aaactgcgtt taatactgtt
    12181 gtctgcttgt cgctcttaag attgttctca aggcttgctg tgtatttatc cttaagtgaa
    12241 tcaatgtaag catcaactgt atcatagcca aacttatcag atacaatatc atctgtaagt
    12301 gccttcttag aatcgatagc ctttgcaatg taattaacct ggaaagtgaa gataactgtc
    12361 tgtccagcta aatctgcgtt gccataatca tctgggaact taacctcgta agcaacttcc
    12421 tcacctacct tatgacctac aagaccagca gtaaatccct cgatatatcc gccgcctgta
    12481 gcagagctgt tgtttcctac atcgataagc tgatcctctg cagaaccgcc atcaaaagct
    12541 accccatcct gagaacctac gtaatcaaca tttacgatag aatcctcttt gatctccttt
    12601 gcgctgctat cctcaacata gatagctgcc tcagaaatag tctttgaaac gtactcatca
    12661 aagcccttgt ctgtgtactc atattcacca tcaagagtga tgtctaagcc cttataatca
    12721 cccaatgtaa caagctcatc cacatcatat tctataggct ttgcgtcaga tttcttctcc
    12781 gtatctgctg actgctcagt ctttgtttct gctttatcct cttctttgct gccacaggct
    12841 gtaaaagaaa aagccaatgt gccaactaaa agcaatgcta aaaatctatt tttcatttgt
    12901 gtaatccctc ctagaaaagt ctgaattagt ttaccacaaa ttcaattttt aggcaaagaa
    12961 aaagctcgct tacttgcgag cctttttctt agctttaggg ggttttttag ttctgtcgta
    13021 cataaccgac atatcaaaaa tcttctttgc caattcagga gtaggttctt tggcaaggag
    13081 acgccactgc cagttaccgc tttctgttcc tggcacgttg attctgttgt attttccaag
    13141 tccaaggaag tcctgcatct gagccacaaa taaaacagaa actgagctca ttccgccacg
    13201 aatcattccc cagttaaagc cctcagcctt tgagatacca aggtacttgc tggcatattc
    13261 cttgtccttt ttatctgctt cttcatacca gcccatgata gtagcattgt catgggttcc
    13321 agtgtagcag atacagtttt tatcgtaggt gtgaggctga taattgttag gctcacctga
    13381 atcaaaagca aattcaagta ccttcatgcc tggccagcca ctatcctgaa gaagcttaac
    13441 aacagtaggt gaaggttctc ccaaatcctc agcaataaat tctatgcttg ggaaagtctt
    13501 tgtaagaagg ccaacaagat ccattcctgg tccttttttc cacttaccat tctttgctgt
    13561 cttctccttt gcaggaacag cccagtactc atcaaagcct ctgaaatgat caattctaag
    13621 aacatcatag agctttgcag caccttcaat tcttcgaatc caccacttat aaccatcctt
    13681 tttcaaggca ttccagtcat agcatgggtt gccccagaac tgtccgtcct cgctgaaata
    13741 atctggtggc acaccagcca cctctactgg ataattatcc tcatcaaggc tgaaaaactc
    13801 tggttcagcc caaacatcgc aggaatccag tgcaacatat ataggaagat ctccaatcac
    13861 ctcaatgcca agactattga tataagtctt aagctttgcc cactgcttaa agaataaata
    13921 ctgaatgtaa acaaaaaatt caatatcctc ttccagcttc ttggtgtact tctcaacagc
    13981 ctttgcctcg tgaagacgaa tgtcttcctc tggccactcc tgccagctaa gctgaccaaa
    14041 atgcttcttt attgccatga aaagcgcata attttccacc caggcatttt tctttctgaa
    14101 atgagaaatc tcaccgagag aatctttgta tcctctctcc tttgcctttt caagaatctt
    14161 gaaacgactt tcgtaaatct ggccataatc cacataacgt gggttagttc cccagttttc
    14221 agcctccact tcttcctttg taagaaggcc ttcctctata agcatttcaa gatcaatgaa
    14281 ataggggttt ccggcaaagg tagaaaagct ctgatatggg ctgtctccgt aactagttgg
    14341 acctaatggt aatacctgcc agtacttttg accggcagcc ttcagaaaat ccgcaaagtc
    14401 atatgcggct tttccaaagg tacctattcc ataaggtgaa ggtaatgaag atatagggag
    14461 caaaattcca ctacttcttt tcataatttt tagtctcctt aaattagcct tttacagctc
    14521 ctgcaataac gcctttaata atgtatttct gtaagcaaat atacataatt atgattggca
    14581 atacagtcat cataatacat gccatcattg gtcccatctc aacgtgtccg tagcttccac
    14641 ggaagtactg aatgagaata ggaattgtca tatatttctt tctgtcgaga acaaggtatg
    14701 gcaaaaggta atcattccaa agccacattg tttcgagaat agcaactgat ataagtgttg
    14761 gcttcaaaat tggaagcaca atctggaaaa atgtctggat tgggttgcaa ccatcaatca
    14821 tggctgcctc ttcaatctca agtggaattg acttcataaa tcctgtgaac ataaataccg
    14881 caagaccagc gccaaaacca aggtaaataa tgcaaatatt atatggtgta tccaggtcca
    14941 ttctgtcagc tgttgatgca agtgtgaaca tcagcatctg gaaaggtact accatcgaaa
    15001 atacaaataa agcatagcat acctttgaga gaattccgtg aactctggtg atgtaccagg
    15061 cacacattga tgtacaaatc aaaatcaaaa ctgcagatga tactgtaatt accaaactgt
    15121 atccaaaggc tgctgcaaat cccttagatg aaagtgcatc aagataattg ctgaagccta
    15181 caaagctctt tgcatctgga agggtaaata cgctgttagt gctgatgaaa gcatcaccct
    15241 taagtgagtt aatcaaaatc ataaacactg gataaatcca gcaaactgcc agaaggcaca
    15301 atacgatgaa cacgataaga cgtgcaacct gttcttttgc tttcattact gctgtacctc
    15361 ctttgattta gtaatcttaa gctgaatcat ggagataaga ataaccataa tacagaaaat
    15421 aactgccttt gcctgaccat aacccttcca ctgtgggcct gtacggctgt agaaggtatt
    15481 gtagatgtta agggcaagca tctctgatgc gtgagcaggc tcaccacctg ttaaagcaag
    15541 gttctgatca aagagcttga agccgtttgt aattgtcagg aacgaacaga ttgtaataga
    15601 tggcattaca tttggaatct ttatcttgaa aagaatctgt cctgttgttg caccatcaat
    15661 ctttgcagcc tcgatgtaat cgtctgggat agactgaaga ccagcgatat aaatgatcat
    15721 catgtatcca atctgctgcc agcacataag gattgttaaa cctataaatc catatgtagc
    15781 attaagtgca agaagtggct tttccaaaag cgaaagcaca cagttgataa gaatctgcca
    15841 aatgtatcca agaacgattc cgccgataag gtttggcatg aagaatactg ttctgaagaa
    15901 atttgaacct ttaatcttat ttgtaagtgc aagggcaata gcaaaagcta ttacatttat
    15961 aagtactgtt gataccacag taaaaagcgc tgtgaaccag aacgaatgcc agaaatcagc
    16021 atctgtaatg gcatacgcat aatttccgaa tccaatgaat gtagatttct ttatagtagt
    16081 aaatttacaa aatgataaat ataagccctg aacaaaggga taaataaatc caaccgagaa
    16141 tgcagccaat gttggcaata caaaaactgg ccagtatttt cttattgctt tttccataat
    16201 tattcctttt tgagtattat ttacagtgaa actttccaaa attatggagg gcgttaggcc
    16261 tcgccctcca atgttagtta tccgcgtttt atgccgtagc aagaaccacg aattgggaag
    16321 aaaaactctt ctatgtgaac tgccctaaga gaatggttga ttcggacagt ttacatcaat
    16381 ataaaattag tgacttgcag cgtactctga agcccatcca tcaacgaatg ctgaaacaac
    16441 atcgtcccat gaacctgtac cagctgcata agctgtaaga gctgaaccta caccgttctt
    16501 ccactcctca gatggcattg ttgtgaagtt ccaagaaact ggagtcttgc ctgcctctgt
    16561 gtaagctcta tcgttaagaa cgaaaaggtt tgttgtatct gctgccttct tgaaaggaat
    16621 aacaccaatc tgctctgaaa gcatctttgt acctgcatca gatgttacca tccatgtaag
    16681 gaaatcaatt gttgcctgaa tatcctcctc agaagcctct gaatttacac accagtagtt
    16741 ttctgtacct gtgcaaagtc cctgattctt ttcgtcgcca gcaccaacat aaattggaat
    16801 catagcaagc tcatcatcag tcataccctt ctttgtaagg tttgcatatt cccaagaacc
    16861 attctgatag aatactgcct gtctgtcagc aaactcgttc tcagcatcat cacctgtctt
    16921 gccagctaaa tcgccaggct tgcatgtagc gttgttgatg tagagatccc aaattgcctt
    16981 atagttgtct aggtacttgc cctcgatagc atctgtagaa tcgataccct tctcctgata
    17041 ctcgaagtag attggaaggt ttgcaaggtg tgtcttgaat ctccagtcag aagaaccatc
    17101 catacctgat gatgtaaatg ctgcaaatcc aagctcatcc ttgcgagctg taatgtcctc
    17161 agcaactttc tttaaatcat caaagctctg aatatcctca agtgtgtaac cagcctgctc
    17221 aagaagcttt gtgtttgtga tgataccgta tgactcgata acgtatgcga tacctgcaac
    17281 tgcatcatca ttgtaaagag cgaatgaatc gcttgttaac tcgttgtaaa gtgaagaacc
    17341 cttaaggtcg tagcagtaat ctgcccagtt tgcaagacct acaggaccat ttacctggaa
    17401 taatgtagga gcctcatcct taacgatttc agatgaaagt gtctcctcgt atgtaccaga
    17461 agctgctgtg ataacagtta caggaacacc tgtctcttct gtgtactgct tagcaatctc
    17521 ctgccaagcc tcatctgcct ctggcttgaa gttaaggtaa taaacctttc cacttgctcc
    17581 atcagctgat gctgaatccc ctgctgaatc tcctgaagcg cttgaaccac aacctgcaaa
    17641 tgttgcagct gccatcattg cgattaaccc cagtgccaat actctctttc tcttcatttc
    17701 ttacactctc ctttttgaag tttaaaattt tatgtttctc atccctatat tcgataggaa
    17761 tgttaaaacc aattcttaaa cttctcggaa ggactcacct tctcgtaatg tggtggacag
    17821 tagtatgtgc ttatgattct tctttccttt aatgatatca accacaagct ttactgcctc
    17881 atcacccatt tcttccatag gctgacagag agtgctcaaa accggattca tgtactcaga
    17941 agcctcaata ccatcgatgc caattactgc tacatccttt ggtattgatt ttccagcctc
    18001 tctcagggct ttcatagcgc ccatagccat attatccgag atggcaaata ctgccgaaaa
    18061 gtcgttattc ttttttaacc atgctttcat gccttcatag gcatcagcaa tgttgtaact
    18121 atttatagga atgatgagat tctcatcaag ttctatacca aaatcattga gagctctttc
    18181 ataaccggcg aatctcacct gactgactga gccatcatct ggaccagaaa gaagaactgc
    18241 aattcttctg tgcccctctt tataaagata ctcaactgct tcataggcag cctgattatc
    18301 atctatgcaa acacttgaat aatctgattt atccagtgtt ccgtactggt tattaaaagt
    18361 acagcaaaca aatggcacat ttatagctga aacctgctcc tttgtataat taagtcttcc
    18421 tccaaggaag ataagaccaa gaagcctctt atctctttcc attctggctg ctgctaagat
    18481 ttcatcatct gatgtgccaa tctgctgcat caccattgtg tatccagctt tttcgatctt
    18541 gtcagaaatc tcagtaataa tctttgtata gaatgggttc gagatacctc ttaccaccag
    18601 tccaatgtta tctgaagatg atttccccaa atctcttgca ctggtatttg gtatgtaatt
    18661 gtattcgttt actacagcaa ggaccttttc ctttgctgat tcactaacat ccgggtgatc
    18721 attaagcaca cgcgaaaccg tgctaacgct gacccctgcc agcttagcta tgtctttgat
    18781 tgtcatttgt tttccttcca ttgcatataa atgctttttt acatggggcc taatccatgt
    18841 tatttggaaa cgtttctggt aacgtttcca gttcatgatt aaatcatagc ctatcgacta
    18901 atctcagtca ataggctaca agtttttcgc tttttacgac aaaaatgcac gacacgtgtc
    18961 gtgcattttt tacaaaatta atttatctag gtgcgataag agaatttaaa tctaatccaa
    19021 tcatttcgct ggcctttgct gtgtattcag gctctccagc atgcttgtag taatcataag
    19081 atagcttatg tgtgttgtta tctctcataa gtccaaaggc aagtccctgt ggaacctcga
    19141 tatatggatc atccttctca cgtgaaagaa taaatccatc gatgtggctg ttgttgttta
    19201 caaccagcat tgcaaatgtg atagctgcgc actggatttc ttcaccctgt gaggaagtgt
    19261 agccctgctc agaaagctta actgtacgaa ctgcacctga tggtgaaagt aattctggct
    19321 ggctaaggaa atcagttaca acatcaatat tataaattga aacgaacttt gtattctggt
    19381 tacgctgaac atttgctgta ggtacccaag gtgtagctga ctttaatgga tagtcataag
    19441 cgtggaaagc aagtctccag tcaatattcc cctgtgctct gatgtaattg ttgaactgag
    19501 taatgaatgc ctttgcacca tgtgtattct ttgtattaac tgcccactgg tgatctgtac
    19561 aaatgtaaac atttgcgttt gcattctcag atttgattgc attaaagaga acgcggaagg
    19621 cattagcata ctcctgagca tataatgaaa gatttccacc acagctcatg tagttccact
    19681 cattccatgc atttacctca ttaccaataa tgaagttatc aacacgtgca ttcattccaa
    19741 aatatgaatg agacatccat cttgaagcta tgaaagagcc tgctgctgca agtaattcga
    19801 taccttcagt agttgttgca ttaagtccgt agtaattgtg ctttccaagg ccattaagtg
    19861 cgtatgggct gataaattca ccctgtgaag cctggtctac taaaagaatc atagtaacct
    19921 gaacaccctg tgcattaaga cgtccaagat aattatcaaa agcagctatg tatcttgtat
    19981 caaagttata agtctttcca ttgtaaacat atggaacacc actaccacct gaaatctttg
    20041 aaagtggaag tgaaactgta gcctgcttta caccaaggtc agcaagtgta cgcataccaa
    20101 ggttatctgt gctggcatct gtaagaatac ccttcttacc gttgtccatt cttgcaatgg
    20161 cacgtgaacc gcatgcctct ggatttgtaa tgtacatgct gtttgaagct gctgtaagag
    20221 ctccgccttt cattacacat acagtaaact tcttaaaaag aactgactca gctgagttct
    20281 tatttaatgg gaaagtgaag tttgcagctg ctgcaactgg tgcctgtgca acctccttac
    20341 ctgtgttacc tgcctgattt gggtcagatg caataagatg ataaatacca tcctctgaag
    20401 ctgtctgtcc tgaagcagca actactacat tgccaccttc aataactgcg cctccaattg
    20461 ctacgccact agtgcccttt gcctctgctg tgaggcttgg cgccccagca aacattgtta
    20521 caataagtgc caaagcaatt acaccgctgg caatcttctt gaaaactttc ataaatccta
    20581 taaatccttc ctatatttat ctatcactca tcataaagct actcatggat tttgttccat
    20641 gagtagccta taaactattt aattatctag ctgtgattaa tgatgtaaga tcaacacctg
    20701 ctattgcgct agcctgtgcg ataatatctg cgcttgatgc attctgatag aagctaaatc
    20761 ccatcttctg cgaaccatcc atattgcaca ttccataaga aagtccctgt gcaagctctt
    20821 ctggatgatc aacctctctg gtaactatca aaccatcaat atatctattg ttctcagcca
    20881 caaggtaagc gtaaacaagt gatgctgcct gaagttcttc accgtcatga cttacataac
    20941 caacctctga catctttaca gatctaactg ctcctgttga tgaaagcatc tctgatgagc
    21001 ataagaaatc tgttaaaaca tctatattag caactgtaac gtaaggagtg ctctggctgt
    21061 gtgaaacgtt ctttgaagtc tcccatgctc ttggagcata aagtggagca ttgtatggat
    21121 gaactgctac tctccaatca acatttcctt cgctcttaat aatgctgttg agctttgtaa
    21181 ggaattcctt acctgaaata tagtaagaag cctctgctct tgaccactgg tgatcaatac
    21241 atgtatatac gtttgcgttt gcattctcag acttgattcc gttgtacata atacggaaag
    21301 cctttgcata ttcctgcata aaagcatcgt ttgaaccaca gttcatgtag ttccaaagcc
    21361 accaagcgtt aacctcatta ccaatgataa agttatctac ctgaccatga cctgtacctg
    21421 cataatgctt tgcaaggtaa gatgcagcgt tctgaagtgc agcaataccc tctgctgtgt
    21481 tagcgttcat tccataataa ttgtgagcgc ctaaaccatc atatgcatat ggattaaaga
    21541 attcctgtga agcattacca tcaacaagga taattacgtt aacctgcatt ccaagcttgt
    21601 tgtacttcat aactgaataa tcgtatcc
//
