LOCUS       NZ_FNDP01000015        22385 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Pseudobutyrivibrio sp. 49, whole genome shotgun sequence.
ACCESSION   NZ_FNDP01000015
VERSION     NZ_FNDP01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudobutyrivibrio sp. 49
  ORGANISM  Pseudobutyrivibrio sp. 49
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Pseudobutyrivibrio.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 14:11:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,130
            CDSs (total)                      :: 3,071
            Genes (coding)                    :: 3,034
            CDSs (with protein)               :: 3,034
            Genes (RNA)                       :: 59
            rRNAs                             :: 4, 4 (16S, 23S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 6 of 37
            Pseudo Genes (incomplete)         :: 31 of 37
            Pseudo Genes (internal stop)      :: 2 of 37
            Pseudo Genes (multiple problems)  :: 2 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:08:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6970
            Orig. end                         :: 29355
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNDP01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="deazapurine"
                     /region_number="1"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /tool="antismash"
     cand_cluster    1..22385
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22385
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[10000:12385](-)"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12385)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     gene            complement(143..1957)
                     /locus_tag="BLP54_RS11700"
                     /old_locus_tag="SAMN05421493_1157"
     CDS             complement(143..1957)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1214:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009663688.1"
                     /locus_tag="BLP54_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_1157"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_090169868.1"
                     /transl_table=11
                     /translation="MTPNRKAIVTNKVKTWFSQPQNIILLLFGIVLTFSTVAPIVAIVQ
                     DTLKIHPGTIDQHLTGRVTGYTIVNYVDLFTSRLAKTNLWIPLLNTVILSVLTCIISIL
                     FGGLFAFLVTRTDMKFKKYLSSIFIFPYIMPQWTLAVVWQHMFYSNKVTGTSDGLLAAI
                     FHIYFPNWWCQGVFPSAMVLGLHYAPFAYILIGGIFKNMDANLEEAATILDTPKWKIMR
                     KVTLPMIKPAILSTILLVFGSAMGSYPVPHYLNLTTLSTKYISMNSMYTGEASILAIIM
                     MIFGVLILGMNQMSLKSRKNYTTVTGKSGQLTKLTIGKAGKYVVGIIFIVITFFTSIWP
                     ILLFALETFLPNPGDYSFLYTGNLAHLTTKWWVTNENITENGMYGQPGIIYNNTIWHAF
                     FGTLLLAVICALIAGTIGTLIGYAVAKNRRSKWANYVNNVAFLPYLMPSIAVGAAFFIL
                     FSNEKINLFNTYTLLILAGVVKYIPFASRSSLNSMLQISNELEEAALIQNASWVKRMVK
                     IIIPIQKSSIISGYLLPFMTCLRELSLFLLLCTQGFILSTTLDYFDEMGLYAFSSAINL
                     ILIVTILIFNTLVNKLTGASLDSGIGGK"
     gene            complement(2007..3389)
                     /locus_tag="BLP54_RS11705"
                     /old_locus_tag="SAMN05421493_1158"
     CDS             complement(2007..3389)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009427916.1"
                     /locus_tag="BLP54_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_1158"
                     /product="hypothetical protein"
                     /protein_id="WP_090169870.1"
                     /transl_table=11
                     /translation="MKRKVLSLIMVASMMMASLVGCGGASSGTATTDSGEATEQTADEP
                     AAELTGIDKIIAEAETMTLDELAQKAIEESNGKTFYGVGNSSRGKSALPLFIEYLQGID
                     SSYNMEFEWQQPKNNKIFEQLSSDSLKSEGTFAMTLIQDGNQIQTKMVDTDILKIFVPK
                     EWAEANGTTPDAFEGFLPLQTLNKVFMYNNTGSAEFNNCWDFVYEGSHPLFMGVDSEIV
                     GKNFLMMLTEDKYAAWMKESFNALDSTKQAYFQPTVKEMEKDASELGLGADAAYSLAWI
                     KLWINNYNEQTDDGPICNTLVDKSAKDQSGLLVYSKLRSVEESASISVNNINVAAYQDG
                     YTGIGGYGYCHYLFLTKNSPLPWTACAFIAFMTTTEQGFDAWGKDMGGYSANPEVAKAI
                     EETYHHSEGGGDEFPAKNDRGYDWWTTDGKLVLEDPAYCSEVSFTVGSWIDIQDHYSAG
                     EE"
     misc_feature    3502..3518
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.21"
                     /tool="antismash"
     gene            complement(3559..4317)
                     /locus_tag="BLP54_RS11710"
                     /old_locus_tag="SAMN05421493_1159"
     CDS             complement(3559..4317)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009428837.1"
                     /locus_tag="BLP54_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_1159"
                     /product="response regulator"
                     /protein_id="WP_090169872.1"
                     /transl_table=11
                     /translation="MTKVLIVDDEKYVRLGIKNDTDWSLIDCEVVGEAANGQEGLEKAK
                     ELKPDVVISDIKMPKMTGIEMSEILLEKYPDMKVIFLTAYDEFEYARAAIRIGASDYLL
                     KPFDDGALEGAIQRLLHLHPNSVNSSKAEEQLIPLTSKSDVENKYIKEAIDFIEKNYSD
                     TDFSVIAMAEAIGVSEGHLSRLFKAETGLSINNYLTRLRIRKAMDYLKDIKVKVYEVAD
                     KVGYQDIAYFSNTFKKLVGKSPSDYQSNGL"
     gene            complement(4310..6031)
                     /locus_tag="BLP54_RS11715"
                     /old_locus_tag="SAMN05421493_11510"
     CDS             complement(4310..6031)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="BLP54_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11510"
                     /product="sensor histidine kinase"
                     /protein_id="WP_090169874.1"
                     /transl_table=11
                     /translation="MNIIRQSFKRQIFVLTLVITLAMVIISGVLTVQGFQARLESDYAR
                     EDKAQELLIRNSLLDMMTKSDEAIDKITEDETLMGAFTLSRENNQVIYAALYEKTAAIR
                     DFASVDLYSNGNCVFSTQTGLTPVTLPKNYSVLKEAKEHHGKTVYGIDLSNSPENAGDL
                     LMAREVLNVLDRGIVVVRIHQDNLKEVVSDGMNSKDGFALVNSHFRAFCEFGTASDGVL
                     LSGIRNNLLRGSLYNDGIRSNIYINDLGNTGLITIYVTPKALDESAIKSGYQIIAIMAI
                     VSVLACLLAANRVSEYFSKPITALAKAMKQFRKGDFDTRIELNRQDEFEQLATGFNKMT
                     TQLKDTMEERVAAERKINETRIAMMQSQLNPHFLYNTLDTIKWVAKANQVPEVATLSSS
                     LAGILRMSISTRQFCTLETELRLVERYCEIQKIRFDDFFDLIINVPEELKDAVVPKLIL
                     QPLVENAIIHGLEDRDDGRLYISAESTEGSLEQGASQLLKIYIEDNGKGISDEMIEILE
                     ADDPSRLEGHLGLNNVNTIIKLYYGKDYGITANRLEVGGTIMTMILPLSKKEPEND"
     gene            complement(6034..7083)
                     /locus_tag="BLP54_RS11720"
                     /old_locus_tag="SAMN05421493_11511"
     CDS             complement(6034..7083)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024921.4"
                     /locus_tag="BLP54_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11511"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_090169876.1"
                     /transl_table=11
                     /translation="MGNGVKKKLLTMVMITEAVLLLFSGCGKISPKKTVREVSEKYSVA
                     DENQLIVYTSHKKEVYLPIIQEFENRTGIYVDIKAGGTQEMMQMADAAFAQGLCDIMFG
                     GGVESYEAWKDNFMSYESSEARELDRNFMSKDGTWTPFTELPIVFIYNKKLVNSSSAPH
                     TWEQLFDSKWKGKIAFADMDNSGTSYTIVSTISQITGDSPENVVSRLYNQLDGNILKSS
                     GDVIPDVSNGTTLVGITLEETALKAINKGYNIDMIYPQDGTSAVPDGCGIVVNAPHEEN
                     AKLFIDFITGYDTQSYAMDEFYRRPVREDVKLRKVFGDITIIDFDVQQSAEDEKIAFDT
                     WHQLTGQED"
     gene            complement(7102..9348)
                     /locus_tag="BLP54_RS11725"
                     /old_locus_tag="SAMN05421493_11512"
     CDS             complement(7102..9348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550078.1"
                     /locus_tag="BLP54_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11512"
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="WP_090169878.1"
                     /transl_table=11
                     /translation="MGFGKLLGYVTEDNQVTIKYENQEVIIQVITEEIIRVLVPYWIKY
                     YKSVAIEGNPQVPVDFEVSQAEDHISITTGSVILQLGDDFSFKFMDKFSDELLSSYDGT
                     RTIMGGLSEEALALLIAEGHLFNADQYKNHKVQQLFKLNPEDRFYGTGDKTGFLNKRGY
                     AYENWNSDIPQMHMENMPALYKSIPFIIGKRPGYTYGLFFDNTFHSYMDLGKESTDYFC
                     YGADDGNLDFYFMAGEKMTDIVEHYTYLTGRAPLPQLWTLGYHQCRWGYESAKDIREVA
                     TKMRENRIPCETVQYDIDYMDGFRVFTWDEENYEPEGQLIKELAEDGFKAVCIIDPGVK
                     ADKGYFMYDEGIKNDYFAKDKDGKVYVNEVWPGDSVFPDFGKEEVRNWWSKSHKKLVDM
                     GMQGIWNDMNEPASFKGPLPLDVQFHVNDRETDHSEMHNVYGHFMSKATFEGMKALTGK
                     RPLVITRACYSGSQKYTAVWTGDNQSVWPHLQMLIPQLCNLGISGFPIAGTDIGGFGGD
                     TKPELLMRWIEAAVFSTFFRNHCAKGHRMQEPWHFGEQTVNVYRKYVELHYRFLPYIYD
                     LLFECQLTGLPVMRPLVLHYEDDENTYNLNDEFLVGENMLVAPVVEQGAFKRMVYLPSG
                     TWIDYWTGQRHAGGNYIIVDAPIDVLPIFIKEGSIIPMYEPVQYVGEKPYDTLELLVAG
                     ESAWGSHYQDNGEDFRYLEGEYNLYSFTYENGKLETDMLHDNYEKYKEIKVINL"
     gene            complement(9468..9959)
                     /gene="queF"
                     /locus_tag="BLP54_RS11730"
                     /old_locus_tag="SAMN05421493_11513"
     CDS             complement(9468..9959)
                     /EC_number="1.7.1.13"
                     /GO_function="GO:0033739 - preQ1 synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550079.1"
                     /locus_tag="BLP54_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11513"
                     /product="preQ(1) synthase"
                     /protein_id="WP_090169880.1"
                     /transl_table=11
                     /translation="MADRAAEGTLTLLGNKNNTYPDNYAPEMLQTFLNKHPENDYFVKF
                     NCPEFTSLCPITGQPDFANIIISYVPGEKMVESKSLKLYLFSFRNHGDFHEDCVNIIMK
                     DLIKLMDPKYIEVWGKFTPRGGISIDPYCNYGKPGTKWEEVAFNRMANHDMYPERVDNR
                     "
     gene            complement(10001..10687)
                     /gene="queC"
                     /locus_tag="BLP54_RS11735"
                     /old_locus_tag="SAMN05421493_11514"
     CDS             complement(10001..10687)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550080.1"
                     /locus_tag="BLP54_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11514"
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_090169882.1"
                     /sec_met_domain="QueC (E-value: 9.4e-65, bitscore: 209.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.4e-08, bitscore:
                     24.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLVSGGVDSTTCLGMAVKEYGSENVVGLSIFYGQRHDKEIK
                     AADAVCEHYNVEHITLDLSTMFQFSDCTLLQHSDGEIPEESYAEQLAKTDGKPVSTYVP
                     FRNGLFLSSASAIALSKGCSKIYYGAHSDDAAGNAYPDCSEAFNNAMNTAIYEGSGKQL
                     EIVAPFISLTKSQVVKKGLEIGVPYELTWSCYEGHEKACGKCGTCIDRKAAFELNGVTD
                     PIAYEN"
     gene            complement(10706..11278)
                     /gene="folE"
                     /locus_tag="BLP54_RS11740"
                     /old_locus_tag="SAMN05421493_11515"
     CDS             complement(10706..11278)
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550081.1"
                     /locus_tag="BLP54_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11515"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_090169884.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 1.5e-67,
                     bitscore: 218.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAINKELIKESIRNIIIALGDDPDRAGLIETPDRVARMYEEVFEG
                     MNYSNQEIADMFNKTFDEDYYDENSQDLVFVKDIEVFSYCEHHLALMYDMKVSVAYIPN
                     GKVIGLSKIARIADMAAKRLQLQERIGNDIAEILQMVTGSEDVAVFIEASHSCMTARGI
                     KNAGARTQTQTLRGKFKTDRDLLARLF"
     gene            complement(11292..11960)
                     /gene="queE"
                     /locus_tag="BLP54_RS11745"
                     /old_locus_tag="SAMN05421493_11516"
     CDS             complement(11292..11960)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="queE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550082.1"
                     /locus_tag="BLP54_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11516"
                     /product="putative 7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_090169886.1"
                     /sec_met_domain="QueE (E-value: 7.2e-39, bitscore: 125.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1e-14, bitscore: 46.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.1e-16, bitscore: 50.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFFVVEKFVSINGEGQHAGELAVFIRLRGCNLACSYCDTRWAC
                     SYEAPAEQMTETEIIDYVKSTGINRVTLTGGEPLKARDIKDLLRAFAAEPDLKVEIETN
                     GSVNIVPFAAIPNAPAFTLDYKLAGSGMEDKMDLSNFAFLQPKDTVKFVCSEVSELDKV
                     CELVDTYGLAMKCTVLISPVFGRIDPADMVNYLIEHKRNDIRLQLQLHKFIWDPNKCGV
                     "
     gene            complement(11963..12385)
                     /locus_tag="BLP54_RS11750"
                     /old_locus_tag="SAMN05421493_11517"
     CDS             complement(11963..12385)
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015550083.1"
                     /locus_tag="BLP54_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11517"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_090169888.1"
                     /sec_met_domain="PTPS (E-value: 1.9e-35, bitscore: 113.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYLTAEASFDGAHFLAGYEGKCSNLHGHRWRVILKIKTDKLQSE
                     GQQRGMVVDFGDVKNALKKETDFFDHSFIYEEGSLKEATVAALQAEDFEMHVVPFRPTA
                     ENFAKYFFDKFKDYGFTVAEVTVYETPNNCASYSED"
     gene            complement(12701..14230)
                     /locus_tag="BLP54_RS11755"
                     /old_locus_tag="SAMN05421493_11518"
     CDS             complement(12701..14230)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012377.4"
                     /locus_tag="BLP54_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11518"
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="WP_090169890.1"
                     /transl_table=11
                     /translation="MKRRIRIITSCALAAALAVSGPACIQNVNAASVTVQANAVSKSQT
                     PVGQHGTLSVKKTSGYAAPTIVDKYGKPVQLHGISTHGVQWFPQYISKDSFRSLRDDWG
                     IDTVRLAVYARENGYTQGNKDLMDKKIEEAVSAAKDLGMYVIIDWHVLSYNPNEDIDAA
                     KTFFTKYALKYKNVDNVIFEIANEPTGTNWYDGSGKDLYTYSKTIAGVIRGTGAKNIII
                     CGTNDWSQRVDQVADKPLKNDGFENIMYTVHFYAATHYDNIKDNVRKAVKAGTPVICTE
                     FGVCDASGNGGYDFSNADDWMKLFKENNISFALWSLCNKNESASVISSSCNKTSNWTES
                     DLTEAGKWLMKTCKELSGNSGIVNPTPTPTPTPTPTPKPTAKPTPTPTPKPTQTPTSKP
                     TPTPTPEAGTTTGGSVTFDIPSDWGTGFSANNTVSNTTNKTLNGWTVEFDSDVEITAIW
                     NAKISSHKGKHYVITNESYNGIVEAGQTVSFGFNGTKKDGSKATFTNVKVR"
     misc_feature    14294..14310
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    14335..14352
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.23"
                     /tool="antismash"
     gene            complement(14487..15770)
                     /gene="ltrA"
                     /locus_tag="BLP54_RS11760"
                     /old_locus_tag="SAMN05421493_11520"
     CDS             complement(14487..15770)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977695.1"
                     /locus_tag="BLP54_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11520"
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_176754547.1"
                     /transl_table=11
                     /translation="MDTSSLMEQILSSDNLNRAYLQVVRNKGAEGVDGMKYTELKEHLE
                     KNGDIIKEQLRTRKYKPQPVRRVEIPKPDGGVRNLGVPTVTDRFIQQAIAQVLTPIYEE
                     QFHDHSYGFRPNRCTQQAILTALDMMNDGNDWIVDIDLEKFFDTVNHDKLMTIIGRTIK
                     DGDVISIVRKYLVSGIMIDDEYEDSIVGTPQGGNLSPLLANIMLNELDKEMEKRGLNFV
                     RYADDCIIMVGSEMSANRVMRNISRFIEEKLGLKVNMTKSKVDKPQGLKYLGFGFYFDS
                     RAHQFKAKPHAKSVAKFKKRMKDLTCRSWGVSNSYKVEKLNQLIRGWINYFKIGSMKTL
                     CREMDKHIRYRLRMCIWKHWKTPQNREKNLVKLGIDRDTARRVAYTGQRIAYVCSKGAV
                     NIAINNKRLALFGLVSMLDYYTERCVTC"
     misc_feature    complement(16233..16247)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.23"
                     /tool="antismash"
     misc_feature    16234..16248
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.7"
                     /tool="antismash"
     gene            complement(16300..18750)
                     /locus_tag="BLP54_RS11765"
                     /old_locus_tag="SAMN05421493_11523"
     CDS             complement(16300..18750)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743577.1"
                     /locus_tag="BLP54_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11523"
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="WP_090169893.1"
                     /transl_table=11
                     /translation="MEKWARIKYTPNLPLGENRTYVTASQEHIDLSCEAACEGMVLLKN
                     DRNLLPIRKGTRIALFGKGTFDYVKGGGGSGDVTVPYIRNLYQGLSQFSSEISIYDKTV
                     EFYEDYVQSQYKAGVVPGMVKEPSLPEDILSDASAYTDTAIISISRFSGEGWDRKVAGV
                     DREIKCESKDLVELGNKIFEHGDFYLTNAEKKMVKQVKENFSNVIVVMNVGGVVDTSWF
                     KNDDSISSVLMAWQGGIEGGLAAAKILLGKVDPSGKLADTFAAKLEDYPSTAGFHESDT
                     FVDYTEDIYVGYRYFETIPKAAKKVNYPFGYGLSYTSFLIENCKAEAFAVLAEEENAVV
                     VSATVTNIGSIPGKEVVQLYYSAPQGKLGKPAKELGGYAKTRLLQPGESQRVSIALLLE
                     DMASYDDLGKVKKAAWVLEKGEYHFYLGTSVRDVCELDYVFELKQNEIVEQVKNRLVPT
                     SLKERMLSDGSFEPLPQLTPVDTYASIFPKEKNVEETGGIELLQTPDVRPQERQQLFFL
                     PEDGGTTKFIDVAECKVSLEDFMAGLTDEQLGTLLGGQPNTGMANTFGYGNLPEAGVPS
                     AQTCDGPAGVRINPEVGVPTTAFPCSTLLACTWNEDICYAVGEAGGAEAKECNFAAWLT
                     PAVCIHRSPLCGRNFEYYSEDPFLTGKQAAAMVRGIQSNNIIATPKHFALNNKESNRKG
                     SDSRASERAIREIYLKAFEIIVKEAEPWSIMSSYNIINGQRASESHDLLTGILRDEWGF
                     DGVVVSDWWGYGDHYKEVLAGNDIKMGCGYTEQLLEAIDKKAIKRKDLERSAERVLKML
                     LKLD"
     misc_feature    complement(18759..18772)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.5"
                     /tool="antismash"
     gene            complement(18793..19908)
                     /locus_tag="BLP54_RS11770"
                     /old_locus_tag="SAMN05421493_11524"
     CDS             complement(18793..19908)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857136.1"
                     /locus_tag="BLP54_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11524"
                     /product="SLC13 family permease"
                     /protein_id="WP_090169896.1"
                     /transl_table=11
                     /translation="MEAVKNFIRNEIVLVVAFVLAVASSFVVHPDSQYIGYIDFRTLSI
                     LLALMITMAGLQRLQVFRQIGELLVSKMSSIRGVVLVLIWLCFFSAMFITNDVALLTFV
                     PFSIVTLSISNRKDLFIIVIVLETIAANLGSMLTPLGNPQNLYLYSIAGMSLGAFVKLM
                     LPYSVVALVMLVLSGFVFVKAAPVTLAEKHIYERTNRDKKMIGMYVFTFLVSILVVARV
                     LDYRIGLVIVVGLTLICDRRVLRKPDYSLLFTFIFLFIFIENIKRIPELSAAINSLVKV
                     NEVGVSIFLSQFISNVPAAILCSGFTDQIDKLIIGTNLGGLGTLIASMASLISFKQYGY
                     IDGADKKKYIGIFTVANIIFLIVMCLIYLLM"
     gene            complement(19960..20754)
                     /gene="proC"
                     /locus_tag="BLP54_RS11775"
                     /old_locus_tag="SAMN05421493_11525"
     CDS             complement(19960..20754)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009462357.1"
                     /locus_tag="BLP54_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11525"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_090169898.1"
                     /transl_table=11
                     /translation="MKIGFIGAGNMGSSMIGGVISSGTVEPQDVMASDIFQATLDELSE
                     EFGVNTSISNRDVVDFADIVILAVKPQYLPDAIEGIKDMDFSDKVVVSIAAGQSLDRLR
                     SLFGTDLKLIRVMPNTPALVGEAMSALSPNEHVTEEECEIVVELFESFGKAEVVPEKLQ
                     DAVVGISGSSPAYVYMFIEALADGAVAEGMPRAQAYKFAAQAVLGSAKMVLETGEHPGV
                     LKDNVCSPGGTTIEAVTALESLGFRSAVIEAERICIERSREL"
     gene            21083..22315
                     /locus_tag="BLP54_RS11780"
                     /old_locus_tag="SAMN05421493_11526"
     CDS             21083..22315
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="BLP54_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421493_11526"
                     /product="MFS transporter"
                     /protein_id="WP_090169900.1"
                     /transl_table=11
                     /translation="MKLFSQYKGLRRANYILFIGRIVTNMGAMIWPMLTLILNKKIGFN
                     ATETALFTICSGILFLPANLLGGHVADRFNKKHVIIYCDIVSIVLFVISGFLPLSIFSI
                     CVLLVGAFFQTLEGPAYQALVADITPAEKREKAFSLLYLGANIGLILSPTLAGLLFNNY
                     LWLCFVISGLSISVSTVLIGLFVKDEKLEEAPTEDVEESADDGLNIWSIIRNSGALIAF
                     IISLAFYQGAYSQFGYLMPLDIAKAFPEKGSIIYGTITSVNCFLVVLFTPIITMIFEKV
                     DLTKKFALGVILQAISFAAFLMSFGIIGGYYISIALFTFGEILTTIMMGAFLAERVPES
                     HRGRIFGVTNFAGAFMQGITQFGSGRMFDAFGPSYAWAFSIAMTMVAVIAALMLVYLDK
                     KEFSQLYVQAD"
ORIGIN
        1 tctaagaatt gtagtctttc cacaacctga tggtccaagc aatgttataa atgaattgtc
       61 agggatatca aggctaacat tatctacacc gaaaaacttt ccccaacgct ttgttatatt
      121 ctccaatttg atttctggca ttttactttc ctccaattcc gctgtcgagg ctagctccag
      181 tcagcttgtt taccaatgta ttaaaaataa gaattgtaac aatcaaaatc aggttgattg
      241 cacttgagaa tgcatataat cccatctcat caaagtaatc aagcgttgtt gataaaataa
      301 atccctgagt acaaagaaga aggaataatg ataattctct taagcaggtc ataaacggaa
      361 gaagatatcc acttatgatt gatgatttct ggataggaat gataatcttt accattctct
      421 ttacccatga tgcattctgt ataagagctg cttcctcaag ctcattacta atctgaagca
      481 ttgagttaag tgagcttctt gatgcaaatg gaatgtactt tacaacacct gcaagaataa
      541 gaagtgtgta agtattgaaa aggttaatct tctcatttga aaaaagaatg aagaaggcgg
      601 cacctacggc aattgaaggc attaggtatg gaaggaacgc tacattattg acataatttg
      661 cccacttgct tcttctattc tttgctaccg catatccgat aagtgttccg attgttcctg
      721 caatcaaagc acagattaca gcaagtaaaa gtgttccaaa gaacgcatgc caaattgtgt
      781 tgttgtatat aatacctggc tggccgtaca taccattttc tgtgatattc tcgtttgtaa
      841 cccaccactt agttgtcagg tgtgctaagt ttcctgtgta caggaaactg tagtcacctg
      901 ggttaggaag gaaggtttca agtgcaaaca aaagaattgg ccaaatactt gtaaaaaacg
      961 taattacgat aaagataatt cctactacgt atttaccagc cttaccgatt gtaagctttg
     1021 taagctgtcc tgatttacca gtaactgttg tgtagttctt tctacttttt aaactcatct
     1081 ggttcattcc aagaatcagc acaccaaaaa tcatcatgat gattgcaaga attgatgcct
     1141 cgccagtgta catactgttc atggaaatgt actttgtaga aagagttgta agattcaaat
     1201 aatgtggaac tggatagctt cccattgcac taccaaatac caaaagtatt gtagaaagga
     1261 tagctggctt aatcattgga agggtaacct ttctcataat tttccacttt ggagtatcaa
     1321 gaatggttgc tgcctcctcg agattagcat ccatgttttt gaaaattcca ccgattaaaa
     1381 tataagcaaa tggtgcatag tgaagaccta aaaccattgc acttgggaat actccctggc
     1441 accaccagtt cggaaaatat atatgaaaaa ttgctgctaa taatccatct gaagttcctg
     1501 taaccttgtt actatagaac atgtgctgcc atacaacagc cagtgtccac tgaggcatga
     1561 tgtatggaaa aatgaaaatt gagcttaaat atttcttgaa tttcatgtct gtacgggtta
     1621 caaggaacgc aaacagacca ccaaacaata tcgaaataat acaagttaaa actgaaagaa
     1681 ttactgtatt taaaagtgga atccaaagat ttgtttttgc cagacggctt gtaaacaaat
     1741 caacgtaatt aacaattgta tatccagtca cacgacctgt aagatgctgg tcgatagtac
     1801 ctggatgaat ctttaatgta tcctgaacaa tggcaacgat tggtgccaca gtagaaaaag
     1861 tcaaaactat tccaaacaac aaaagaatta tattttgagg ttgggagaac catgttttga
     1921 ccttatttgt gacaatagct tttctattag gtgtcatact ttattctcct taaaaggggg
     1981 cgccgcaggc gacgccccac caatttttac tcttctcctg ctgagtaatg atcctgaata
     2041 tcaatccaag aacctacagt aaaggatacc tctgagcaat atgctggatc ctcaagaaca
     2101 agctttccat cggttgtcca ccagtcatat cctctatcgt tctttgctgg gaactcatct
     2161 ccgccacctt cgctgtggtg atatgtttcc tcgatagcct ttgctacttc tgggttagct
     2221 gagtaaccac ccatatcctt gccccatgca tcaaagccct gctctgttgt tgtcatgaaa
     2281 gcaatgaatg cacatgctgt ccatggaagt gggctgttct ttgtaaggaa gagataatgg
     2341 caatatccat atccaccgat tcctgtgtaa ccatcctgat atgcagctac attaatgttg
     2401 tttacagaaa tagaagctga ctcctcaact gaacgaagct tagaatatac taacaatcct
     2461 gactgatcct ttgctgactt atcaacaagt gtgttacaga taggaccatc atctgtctgc
     2521 tcgttgtagt tgttaatcca aagcttaatc caagcaagtg aataagctgc atctgcgcca
     2581 agtccaagct cagaagcatc cttctccatt tccttaactg ttggctggaa gtatgcctgc
     2641 tttgtagaat caagtgcatt gaatgactcc ttcatccatg ctgcatactt gtcttctgta
     2701 agcatcataa ggaagttctt acctacgatt tctgaatcaa cgcccatgaa taatggatgt
     2761 gaaccttcat atacgaaatc ccagcagtta ttaaattcag ctgaacctgt gttgttgtac
     2821 atgaaaacct tattaagtgt ctgaagtgga aggaatccct caaatgcatc tggagtagtt
     2881 ccatttgcct ctgcccactc ctttggtaca aatattttaa ggatatctgt atccaccatc
     2941 tttgtctgga tctgatttcc atcctgaata agagtcattg caaatgtacc ttcactctta
     3001 agtgagtcag atgaaagctg ctcaaaaatc ttgttgttct ttggctgctg ccactcaaac
     3061 tccatgttgt atgagctgtc gattccctga agatattcga taaataatgg aagtgctgat
     3121 ttaccacggc ttgagttacc aacaccatag aaagtcttgc cgttagactc ctcgatagcc
     3181 ttctgagcca actcatcaag agtcattgtc tctgcttcag ctataatctt gtcgattcct
     3241 gtgagctctg ctgcaggttc atccgctgtc tgctctgtag cttcacctga atctgtagtt
     3301 gctgtgcctg agcttgcgcc accgcaacct accaggctgg ccatcatcat agatgcgacc
     3361 ataattaatg ataatacctt tcttttcatt cttaccctcc taatcattat agattatttt
     3421 taccctgcat ttagggcttc tctctatcta atagtctata tatagtggat tagaatgtgt
     3481 atgagacaaa actgatatta tttgtaattt ttgaacatac taaaaaaaga gctggaatct
     3541 catccagctc tcactcactt atagtccatt actttgataa tctgatggag attttcccac
     3601 cagcttttta aaggtgttag aaaaatatgc tatatcctga tagcccactt tatctgctac
     3661 ttcgtatact ttaactttta tatccttcag ataatccatg gcttttctta tacgtagtcg
     3721 ggtaagataa ttgttgatgc taagacctgt ttcagcttta aacagcctgc tcaaatgccc
     3781 ctcactaacc cctatagctt cagccattgc aatgacacta aaatctgtat cactataatt
     3841 tttttctatg aagtcaattg cttccttgat atatttattt tccacatcag acttactcgt
     3901 tagcggaata agctgttcct cagccttgct gctgttaaca gaatttgggt gaagatgcaa
     3961 tagtctctga atagctccct ccaatgcccc atcatcaaaa ggttttaaaa gatagtctga
     4021 tgctcctatt ctaatcgctg ctcttgcgta ctcaaactca tcataggctg tcagaaagat
     4081 taccttcata tcaggatact tttctagtag tatttccgac atttctatac ctgtcatctt
     4141 tggcatttta atgtcggaga taaccacatc tggctttagt tccttcgcct tttccaagcc
     4201 ttcctgacca ttggctgctt cacctactac ctcgcagtca atcaacgacc agtctgtatc
     4261 attttttatt ccgagacgta catatttctc atcgtctaca attaaaacct tagtcatttt
     4321 ctggctcctt ttttgatagg ggcagaatca tagtcataat ggttccacca acctccagcc
     4381 tattagctgt tattccataa tcttttccgt agtacaattt aattatcgta tttacgttat
     4441 ttaatccaag atgaccttcc aatctgcttg gatcatctgc ctccaaaatc tctatcatct
     4501 catcgctaat acccttaccg ttatcttcga tgtagatttt taaaagctga cttgctccct
     4561 gctctaacga gccttctgtg gactcagcag aaatatacag tctgccatca tctctatctt
     4621 ccaagccgtg aataattgca ttttccacta gtggctgaag aatcagcttt ggcacaactg
     4681 catccttaag ctcctctggc acattaataa tcaaatcaaa gaaatcatca aaacgaatct
     4741 tttgaatttc gcagtatctc tccacaagcc ttaattcagt ctccaacgta caaaactgcc
     4801 tggtggaaat agacattctg agaattcctg caagacttga tgacaacgta gctacttctg
     4861 gcacttgatt cgcctttgcc acccatttaa tggtatcaag tgtgttgtac aaaaaatgtg
     4921 gattaagctg cgattgcatc atggcaattc gggtttcatt tatctttcgc tctgctgcaa
     4981 ctcgctcctc cattgtatct ttcaactggg tagtcatttt attaaagccc gttgccagct
     5041 gttcaaattc atcctgtcga ttcagctcta tcctggtgtc aaaatctccc tttctgaatt
     5101 gcttcatagc cttggctaaa gctgtaattg gctttgaaaa atattcactt actctgtttg
     5161 cagccagtaa acatgcaagc actgaaacta tcgccataat agcaataatt tgataaccac
     5221 ttttaatggc tgattcgtca agtgcctttg gagttacata aattgtaatc agccccgtgt
     5281 tgcccaaatc attgatataa atatttgatc ttattccatc attatatagg gagcctcgca
     5341 acagattgtt tcgtatccca ctgagtagca ctccatcaga agctgttcca aattcacaaa
     5401 aagctctaaa gtggctgttt acaagggcga atccatcctt tgaattcatt ccatcactta
     5461 caacttcctt aagattatcc tgatgaattc ttacaacaac tattccccta tcaagaacat
     5521 ttagcacttc cctggccatc agtaaatctc cagcattttc agggctattg cttaaatcaa
     5581 tgccgtaaac tgtctttcca tgatgctcct tcgcttcctt caaaacagaa taattcttag
     5641 gtaatgttac tggagtcaac cctgtttgcg tactgaaaac acaatttcca ttagaatata
     5701 agtcaactga cgcaaagtct cttattgctg cagttttctc atataaagca gcatatatca
     5761 cctgattgtt ttctctgctt aatgtaaaag cacccatcag ggtttcatct tcggtaatct
     5821 tatctatggc ctcatctgat ttggtcatca tatcaagaag actatttctg attaaaagct
     5881 cctgtgcctt atcttctctg gcatagtctg actctagtct tgcctgaaac ccctgcactg
     5941 ttaagacacc gctgataata accatagcca gcgtaatcac aagggttaaa acaaaaattt
     6001 gtcttttgaa ggattgtctg ataatgttca taatcaatcc tcctgacctg tgagctgatg
     6061 ccaggtgtca aaagctattt tttcatcctc tgctgactgc tgcacatcaa agtctataat
     6121 agtaatatca ccaaaaactt tacgaagctt cacatcttcc cttacaggcc tgcggtaaaa
     6181 ctcatccatt gcatagcttt gagtatcata ccctgtaata aaatctataa acagctttgc
     6241 attttcttcg tgaggagcgt tcaccactat tccacaacca tcagggacag cactagtacc
     6301 atcctgtgga taaatcatat ctatgttgta tcccttgttg atagccttga gggcagtctc
     6361 ctccaatgtg attcccacaa gggttgttcc atttgaaaca tcaggaatta catctccaga
     6421 agactttagg atattaccat ctagctgatt ataaagcctg ctcaccacat tctctggcga
     6481 atctcccgtt atttgggaaa tggtagaaac tatagtatag cttgtacctg aattatccat
     6541 atccgcaaat gcgattttac ctttccactt ggaatcaaat aactgctccc aagtgtgtgg
     6601 cgcactgctt gaattaacaa gtttcttatt gtaaataaaa acaattggaa gttctgtaaa
     6661 aggagtccag gtgccatctt ttgacatgaa atttctatct aattctctag cttcactgga
     6721 ttcgtatgac atgaaattat ccttccatgc ctcataactt tccactccgc ctccaaacat
     6781 gatgtcgcat agtccctgtg caaacgctgc atctgccatc tgcatcattt cctgagttcc
     6841 acctgcttta atatcaacat aaattcccgt gcgattttca aactcctgaa taattggaag
     6901 atatacctcc ttcttgtgag aggtatagac gataagctga ttttcatcag ccacagaata
     6961 tttttcagaa acttccctta cagttttctt aggggatatt tttccacagc cagaaaacag
     7021 aagcaaaact gcttctgtaa tcatgaccat agttaacaat ttctttttaa ccccattccc
     7081 cataacatta ctcacaatct tttagagatt aatcacctta atctctttat atttctcata
     7141 attgtcatgc agcatatctg tctctagttt accattttca tatgtaaagc tgtagagatt
     7201 atattctccc tcaagatatc taaagtcttc cccattatcc tgataatgag agccccaggc
     7261 gctttctcca gctactaaaa gctctaacgt atcatatggc ttctctccca catactgaac
     7321 tggctcatac ataggaatta tgctgccctc tttaatgaat attggaagca catcaattgg
     7381 tgcatcaaca ataatgtaat ttccacctgc gtgacgctgg cctgtccaat aatcaatcca
     7441 tgttcctgat ggaagataaa ccattctctt aaaggctccc tgctctacta caggtgccac
     7501 aagcatattc tcaccaacaa ggaactcatc attaagatta taggtgttct cgtcatcctc
     7561 gtaatgaagc accaatgggc gcattactgg aagacctgta agctgacatt caaataataa
     7621 atcataaatg tatggtaaga agcgatagtg cagctctacg tatttacgat atacatttac
     7681 agtctgctct ccaaaatgcc aaggttcctg cattctgtga cccttagcac aatgatttct
     7741 aaagaaggta gagaaaacag ctgcctcaat ccatctcata agaagctctg gctttgtatc
     7801 tcctccaaat ccacctatgt cagttcctgc aataggaaaa ccgctgatac caagattaca
     7861 aagctgtgga atcagcatct gaagatgtgg ccatacactc tgattatctc cagtccaaac
     7921 agcagtatat ttctgagaac cactgtagca agctcttgtg ataacaagtg gtcgctttcc
     7981 tgtaagcgcc ttcattccct caaaggtagc cttactcatg aaatgaccgt atacattgtg
     8041 catctcactg tggtctgtct ctctgtcatt tacatggaac tggacatcca aaggaagtgg
     8101 ccccttaaag ctggctggct cattcatatc attccagatt ccctgcatgc ccatgtccac
     8161 aagcttctta tgactcttgc tccaccagtt tctaacttct tctttaccaa aatcagggaa
     8221 tacagaatct cctggccaaa cctcatttac atataccttg ccatccttat cctttgcaaa
     8281 gtaatcattc tttatgccct cgtcgtacat gaaatagccc ttgtccgctt ttacgccggg
     8341 gtcaatgatg cagacagcct taaagccatc ctcagcaagc tcctttataa gctgtccctc
     8401 tggctcgtag ttttcctcat cccatgtgaa gactctgaag ccatccatgt aatcaatatc
     8461 gtactgaacc gtctcgcaag ggattctgtt ctcacgcatc tttgtggcaa cttcacggat
     8521 atcctttgca ctttcatagc cccagcggca ctgatgatag cccagtgtcc aaagctgtgg
     8581 cagtggtgca cgtcctgtaa gatatgtata gtgctccaca atatctgtca tcttttcgcc
     8641 agccatgaag tagaaatcca agtttccatc atctgcacca tagcagaaat aatctgtgct
     8701 ctccttgcca agatccatat agctgtggaa ggtattatca aagaaaagac cataagtgta
     8761 tcctggtcgc tttccaataa taaatggaat tgatttatag agagctggca tgttttccat
     8821 gtgcatctga ggaatatctg aattccagtt ctcataagca tagcctcgct tatttaagaa
     8881 gccagtctta tcacctgtgc cgtagaatct gtcctctgga ttaagtttga aaagctgctg
     8941 aaccttatga tttttgtact ggtcagcatt aaaaagatgt ccttccgcaa taagaagtgc
     9001 taacgcttcc tcagataatc ctcccatgat agtacgggtg ccatcatagc ttgaaagcag
     9061 ttcatctgag aatttatcca tgaatttaaa gctgaaatca tcccccagct gaagaataac
     9121 ggagcctgtt gtaatggaaa tatgatcctc agcctgtgat acctcaaaat ctacaggcac
     9181 ctgtggatta ccctcgatgg caactgactt gtaatatttt atccaataag gaactaatac
     9241 cctgataatt tcctctgtaa ttacctgaat aattacttcc tgattttcat atttgatagt
     9301 aacctgattg tcctcggtta catatcccaa taacttaccg aatcccataa aatcgtcctc
     9361 ctagctaaaa actaaatgta gaatatcata ttgctggaaa cgtttccagt aatatttcaa
     9421 aaaatggact gacaatgtaa ttttacctta tcagtcccat aaaaatttta tctattatca
     9481 actctctcag gatacatatc gtggtttgcc atacgattga aagctacctc ttcccacttt
     9541 gtacctggct tgccatagtt acaatatggg tcgatggaaa tgcctcctct tggagtaaac
     9601 ttgccccaaa cctcgatgta cttaggatcc ataagcttga taagatcctt catgatgatg
     9661 tttacacaat cctcatggaa gtcaccatga tttctaaaac tgaaaagata aagctttaat
     9721 gacttgctct ctaccatctt ttcacctgga acataagaaa tgataatatt tgcaaaatca
     9781 ggctgaccag taataggaca aagtgatgtg aactctggac agttaaactt tacaaagtaa
     9841 tcattctcag gatgcttgtt taagaatgtc tgaagcatct ctggtgcgta gttatctgga
     9901 tatgtgttgt tcttgtttcc aagaagggta agtgtaccct cggctgctct atctgccata
     9961 attatttacc tccgtacttc cgatatcgta tatacgataa ttagttctca tatgctattg
    10021 ggtctgtcac cccattaagt tcaaatgctg cttttctatc aatgcatgtg ccgcattttc
    10081 cacaagcctt ctcatgtcct tcatagcagc tccaagtaag ctcataagga actccgattt
    10141 caagtccctt ctttacaacc tgagactttg taaggcttat aaatggtgca acaatttcaa
    10201 gctgctttcc actaccttca tagatagctg tgttcatagc attgttaaat gcctctgaac
    10261 aatctgggta agcattgcct gcagcgtcat cactgtgtgc tccataataa atctttgagc
    10321 atcccttaga aagtgcaata gcactggcgc ttgaaaggaa aagaccattt ctaaatggca
    10381 cgtatgtgct tacgggcttt ccgtctgtct tagcaagctg ctcagcataa gactcctctg
    10441 gaatctctcc atcagagtgc tgtaaaagtg tgcagtcact aaactggaac attgtagata
    10501 aatcaagtgt gatgtgctct acattataat gctcgcaaac agcatctgct gccttaatct
    10561 ccttatcatg acgctggccg tagaagatcg aaagacctac tacgttctcg cttccatatt
    10621 cttttactgc cataccaagg caagtggtag aatccacacc accactgact aaaactaatg
    10681 ctttcatata cacctcatcc gctttttaaa ataatcttgc caacaaatct ctgtcggttt
    10741 tgaactttcc acgtaaagtc tgtgtctgag tgcgagcacc tgcattctta attccacgtg
    10801 ctgtcatgca agagtggcta gcctcgataa atacagccac atcctcagag cctgtaacca
    10861 tctgaagaat ctcagcgata tcatttccga ttctctcctg aagctggaga cgcttagccg
    10921 ccatatcagc gattcgtgca atcttgctga gaccgattac ctttccattt ggaatatagg
    10981 ctacactgac cttcatatca tacataagtg caagatgatg ctcacagtag ctgaacacct
    11041 cgatgtcctt tacgaataca aggtcctgac tattctcatc atagtagtcc tcgtcaaagg
    11101 tcttgttgaa catatcagca atctcctgat tgctgtaatt cattccctcg aaaacctcct
    11161 catacatgcg ggcaactctg tcaggagtct cgataagacc tgctctgtca ggatcatccc
    11221 caagggcaat gataatattt ctaatgcttt ccttaattaa ttccttatta attgccatac
    11281 tatcctcttt cttacactcc acacttattt ggatcccaaa taaatttatg aagctggagc
    11341 tgtaatcgaa tatcattacg cttgtgctct atcagataat taaccatatc tgctggatcg
    11401 attcgtccaa atacagggct gattaaaact gtacatttca tagccaagcc gtatgtatca
    11461 acaagctcac agaccttatc cagctcgctt acctctgagc atacaaactt aacagtgtcc
    11521 tttggctgaa gaaaggcaaa attagataaa tccatcttat cttccatacc agagcctgca
    11581 agcttgtaat ccaaggtaaa tgcaggtgca tttggaatag ctgcaaatgg gacaatatta
    11641 acacttccat ttgtttctat ctccacctta aggtctggtt ctgctgcaaa agctcttaac
    11701 aggtccttta tatcccttgc cttaagtggc tcgccaccag taagggtgac acggttaatt
    11761 ccagttgact ttacataatc tataatttca gtttctgtca tctgctcggc tggtgcctca
    11821 tagctgcatg cccatcttgt atcacaatag ctacaagcaa ggttacatcc acgaagtctg
    11881 ataaatacag ctaactcacc agcgtgctga ccttcgccat taatgctgac gaacttctct
    11941 actacaaaaa atactgacat tattaatcct ccgaatagct tgcacagtta tttggagtct
    12001 catacactgt cacttctgca actgtaaaac cataatcctt aaacttgtca aaaaagtact
    12061 ttgcgaaatt ctctgctgta ggtctgaaag gcactacatg catctcgaag tcctctgcct
    12121 ggagagctgc tactgtagcc tccttaagag aaccttcttc atatataaag ctgtgatcaa
    12181 agaaatctgt ttccttttta agagcatttt tcacatcgcc aaaatctact accattccac
    12241 gctgctgtcc ttcgctctgc agcttatcag tcttaatttt taaaataact ctccagcgat
    12301 gaccatgtaa attagaacac tttccctcat agccagctaa aaagtgagct ccatcaaatg
    12361 aagcctctgc agttaaataa tacattgaaa atctcctatg aaaccggacc tagaatatct
    12421 cagaaataaa aaagactgcg caccggcagc ctcgaaaatc acatagataa ataacgcaag
    12481 tccgagtttt gtttatagac aggatggtac aaacgaactg tctctcactc ttacgagtga
    12541 atttctattt tttaattgcc tgactataat acaacctgaa ataaaaaaaa gcaagcaaaa
    12601 aagcgaaagg tcgcaacagc atacactatt gcgaccacat atatatatta gggagtataa
    12661 aaatatgaaa aaggttgggt tttacgaagt catacaaaca ttaacgtact ttaacgtttg
    12721 taaatgtggc tttagaacca tctttcttag ttccgttaaa gccgaatgaa acagtctgtc
    12781 cagcctctac tataccgtta taagattcgt tggtaattac gtagtgctta cccttgtgag
    12841 atgaaatctt agcattccag attgctgtaa tttcaacatc actatcgaat tcaactgtcc
    12901 atccattaag ggttttgttt gttgtgttac taactgtgtt atttgctgaa aagcctgtgc
    12961 cccaatcaga tggaatgtca aaagtaacac ttccacctgt tgttgtgcct gcctcaggag
    13021 taggagtagg ggtaggtttt gaggtaggtg tttgggtagg ctttggagtt ggcgttggtg
    13081 ttggcttagc tgtaggctta ggtgttggtg taggagttgg tgtaggggta ggagtagggt
    13141 ttacaatacc actattacct gaaagctcct tacaagtctt cataagccac ttgccagcct
    13201 ctgtaagatc tgattctgtc cagttgctag tcttattaca tgatgaagaa attactgaag
    13261 cagactcatt cttattacat aagctccata atgcaaaact gatgttgttc tccttgaaga
    13321 gcttcatcca atcatcagca ttgctgaaat cgtatccgcc gttaccagaa gcatcacaaa
    13381 caccaaactc tgtacagata actggtgtgc ccgccttaac ggcctttctt acgttgtctt
    13441 taatattgtc ataatgtgtt gccgcgtaga agtgaactgt gtacatgatg ttttcgaagc
    13501 catcattctt aagtggcttg tcagcaacct gatctactct ctgtgaccag tcgtttgtgc
    13561 cgcagatgat gatgttcttt gcacctgtac ctctgattac accagcaatt gtcttgctgt
    13621 aggtgtataa atccttgccg cttccgtcat accagtttgt accagtaggt tcgttagcaa
    13681 tttcaaaaat tacattatca acattcttat attttaatgc atactttgta aagaatgtct
    13741 ttgccgcgtc gatgtcttca tttgggttgt agctaagtac atgccaatcg atgattacat
    13801 acatgccaag atccttagct gctgaaacag cttcctcgat cttcttatcc attaaatcct
    13861 tattgccctg agtgtatcca ttctctctgg catatactgc aagtcttaca gtatcgattc
    13921 cccaatcatc cctcagactc ctaaaactat ccttgctaat gtactgtggg aaccactgta
    13981 caccatgtgt actaattccg tgcaactgta ctggcttgcc atatttgtct acgatagttg
    14041 gcgcagcgta acctgatgtc ttttttactg atagagtacc atgctgtcca acaggagtct
    14101 gagatttaga cacagcgttc gcctgtactg taacgcttgc tgcattaaca ttttgaatgc
    14161 atgcgggtcc gctaaccgcc aatgctgctg ctaatgcgca tgaagtaata attcttattc
    14221 ttcttttcat tacatattct gccctttctg tttattaata aacaatttac aagaaactgt
    14281 ttatttttgt ttaccggtac aatataacat aacactttta gtttgtaaac aattttgtaa
    14341 tatttatgtt acaaatatac atttttctgt aataaataat tcagagtttt tcccatgttt
    14401 acaatcgagt aggagggaga tttaatcaat ctcccgacct ctcacaccac cgtacgtacg
    14461 gttccgtata cggcggttca atcaacttaa caagtaacac atctttcggt gtagtaatct
    14521 aacattgaga ctaatccaaa taaggctagt ctcttgttgt ttattgctat attcaccgct
    14581 cccttgctgc aaacataggc tattctttga cctgtgtatg caactcgtct tgcagtatct
    14641 ctgtcaattc caagttttac aagattcttt tcacgattct gtggagtttt ccagtgtttc
    14701 caaatgcaca tgcggagtct gtatcggatg tgtttatcca tctccctaca taaagttttc
    14761 atactaccta tcttgaagta gtttatccaa cctcgaataa gctgattaag tttctcaact
    14821 ttgtagctgt tgctaacgcc ccaactacgg caagtaaggt ctttcattct tttcttaaac
    14881 tttgctactg attttgcatg tggttttgcc ttaaactggt gtgctcttga atcaaagtag
    14941 aatccgaatc caaggtattt aagtccttgc ggcttgtcaa ctttactctt ggtcatgttg
    15001 accttgagac ctagtttctc ctcaatgaat cgagagatgt ttctcataac tctattagca
    15061 gacatttcac taccaaccat gatgatacaa tcatcagcgt atcttacaaa gttaagccca
    15121 cgcttttcca tctccttatc aagttcattc aacatgatat tcgccaataa cggcgagaga
    15181 tttcctcctt gtggtgttcc cacaatagag tcctcgtact catcatcaat catgattcca
    15241 ctgactaggt attttctaac gatagaaata acatctccat ccttaatagt tctacctatg
    15301 atagtcataa gtttgtcgtg atttactgtg tcaaagaact tttccaagtc aatatctaca
    15361 atccaatcat taccgtcatt catcatgtcg agcgctgtta ggattgcttg ctgtgtacat
    15421 ctattaggtc tgaatccata actgtggtca tgaaattgtt cctcatagat tggtgttaat
    15481 acctgtgcta tagcttgttg gataaatctg tctgttactg ttggtactcc taggtttctg
    15541 acaccaccat caggctttgg tatctccact cttcgtactg gctgaggttt atactttctt
    15601 gtcctcaact gttccttgat tatatcgccg ttcttttcaa ggtgttcttt gagttctgtg
    15661 tacttcattc cgtccactcc ctctgcacct ttgtttcgta cgacttgcag atatgctcta
    15721 ttgagattat cactagatag tatctgctcc attagactac ttgtgtccat gcgttctttc
    15781 ctttccgtct cgctagattt gaccatcctt cacccgattg gttacggcag atgttgtcat
    15841 ttctgcaata cgagacatac tcaaacttat tgattgttca ccccttcgct ccatctccat
    15901 tacagaaatt tcttcactac tatgggctcg gctgacttct cacagttcgt tgttactagg
    15961 ctaatggaac ctctgtgaga cctccacgct taaggtgcac gctctttctc tccatatatc
    16021 cgccacattt actctgctac tacaaatgtg atagttattg gacttcgttg ctttacgcca
    16081 acttatccct cgtagcctag ccttatatgt gatttctgtc cgtcggacca gagatttgct
    16141 tacagcttcc ttcagattcc gcctcacgat ggacaccctt gctgttcagc tatacacttc
    16201 ccactatctg ggcgtgttcg ggacttgcac ccgttagagc gcgcccatgg cgcgcaaacg
    16261 taaaaaaggg acttccgaag aagtcccaaa aaatttctat taatctaatt tcaacagcat
    16321 ttttagaaca cgctcagcgc tacgttccaa atctttacgt ttaattgctt ttttatcaat
    16381 tgcttccagt agctgctctg tataaccgca gcccatctta atatcatttc ctgcaagcac
    16441 ttccttatag tggtctccat atccccacca gtcgctgaca acaactccgt caaaccccca
    16501 ttcatcacga aggattcctg tgagaagatc atgggattct gatgcacgct gaccattaat
    16561 gatattgtaa gaagacataa tgctccaagg ctctgcctct tttacaataa tctcaaatgc
    16621 cttcagatag atttctctta ttgcacgctc tgaagctctg gaatcactgc cctttctgtt
    16681 tgactcttta ttgttaagag caaaatgctt aggtgtagcg ataatattgt tgctctgaat
    16741 tccgcgaacc atagctgctg cctgctttcc tgtgaggaaa ggatcctcag aataatattc
    16801 aaagtttcta ccgcaaaggg gacttctgtg aatacataca gctggtgtaa gccatgctgc
    16861 aaagttacat tcctttgcct ctgctccacc tgcttcgccc actgcgtagc aaatatcttc
    16921 attccatgtg caagctaaaa gtgtagaaca tgggaatgct gtagtaggaa ctcccacctc
    16981 aggattgatt cttacacctg caggaccgtc acaggtctgt gccgatggaa cacctgcctc
    17041 tggaagattt ccatagccaa atgtatttgc catgcctgta tttggctgac cgccaagtaa
    17101 tgttccgagc tgctcatctg taagtcctgc cataaaatcc tcaagactaa ctttacactc
    17161 ggccacatcg ataaactttg ttgttccacc atcctccgga aggaagaaaa gctgctgtct
    17221 ttcctgtgga cgtacatctg gagtctgtaa taattcgatg ccacctgtct cctccacatt
    17281 tttctcctta gggaaaatgg atgcgtatgt atctactggt gtaagctgtg gtaacggctc
    17341 aaagctgcca tctgaaagca ttctttcttt aagggatgta ggaacaagtc tgttctttac
    17401 ctgttccact atctcattct gctttaactc aaaaacataa tccaactcac atacgtctct
    17461 tacagaggta ccaaggtaga aatgatactc acccttttca aggacccaag cagccttttt
    17521 caccttgcct aaatcatcgt aagacgccat atcctccaag agaagtgcga tggaaacccg
    17581 ctgactctct cccggctgaa gcaatctggt cttcgcatat ccaccaagct ccttagctgg
    17641 ctttccaagc ttaccctgtg gggcgctgta ataaagctgt actacttcct tgcccgggat
    17701 acttcctata tttgttactg tggcagaaac taccactgca ttttcctctt ctgctaaaac
    17761 tgcaaatgct tctgccttac agttttcaat gagaaatgat gtgtatgaca agccatatcc
    17821 aaatggataa ttaacctttt tcgcagcctt tggaatagtt tcaaaataac ggtagcctac
    17881 gtaaatatcc tctgtgtaat ccacgaaagt gtcgctctcg tggaagcctg ctgtggaagg
    17941 ataatcctct aattttgctg caaatgtatc tgccagcttt cctgatggat ctacctttcc
    18001 aagaagtatt ttggctgctg caagaccgcc ttctattcca ccctgccatg ccataagcac
    18061 agaagaaatg ctgtcatcat ttttgaacca gctggtgtca actacaccac ccacattcat
    18121 aacaacaata acattggaga agttttcctt aacctgcttt accattttct tttcagcatt
    18181 tgtaagataa aaatctccgt gctcaaaaat cttatttcca agctctacca aatccttgga
    18241 ttcgcatttg atttcacggt ctactccagc tacctttcta tcccagcctt cccctgaaaa
    18301 acggctgata gaaataatag ctgtatctgt atatgcagag gcgtcagaaa gtatatcctc
    18361 aggaagtgat ggttccttta ccatgcctgg aactactcca gctttgtact ggctctgaac
    18421 ataatcctca taaaactcta cagtcttatc ataaatagaa atctccgaag agaactgtga
    18481 aagtccctga tagagatttc gtatatacgg tacagtgaca tcaccgctgc caccgccacc
    18541 cttaacataa tcaaaggtgc cctttccgaa aagagcaatt ctggttcctt tcctgatagg
    18601 aagaaggttc ctgtcatttt tcagtaatac cataccttca catgcagcct cacaggacag
    18661 gtcgatgtgt tcctgactag ctgtaacata ggtcctgttc tctcctaaag gaaggtttgg
    18721 tgtatacttg attcttgccc atttctccat agcgcacctc acaataatta taaattttta
    18781 ctatattcta ttttacatca acaggtagat taaacacata acaattaaaa aaataatatt
    18841 tgctactgtg aaaataccta tatatttttt cttgtccgct ccatctatat agccatactg
    18901 tttaaaggaa atcaggctgg ccattgatgc aataagtgtt ccaagtccac caaggtttgt
    18961 tccaataata agcttgtcta tctgatctgt aaaacctgag caaagaatag ctgcaggaac
    19021 attacttata aactggctaa ggaatataga aactcccacc tcatttacct ttacaaggct
    19081 gttgattgca gcactgagct ctggaattct cttgatattt tcaataaaaa taaacaggaa
    19141 aatgaatgta aataaaagtg aataatctgg ctttctaagc actcgtctgt cacagataag
    19201 tgtcagtccc actacgatta caagaccgat tctataatct aaaacccttg ccaccacaag
    19261 gatagaaact aaaaacgtaa atacgtacat tcctatcatc ttcttgtctc tgtttgtgcg
    19321 ctcatatata tgcttttctg ccaaagttac tggagctgct ttcacgaata caaatccgct
    19381 aagcacaagc attacaagtg ctactacact gtatggcaac ataagcttta cgaatgctcc
    19441 aagactcata cccgcaatgg aatacagata aagattctgt ggattaccaa gtggtgtaag
    19501 catacttcca agatttgctg ctattgtctc aagcacaatt actatgatga acaaatcctt
    19561 gcgatttgaa atagacaaag taactataga aaatggcaca aaggtaagaa gggccacatc
    19621 atttgtgata aacatagctg agaaaaagca aagccaaatg agcaccagaa caactcctct
    19681 gatggagctc atctttgaaa ctaaaagctc tcctatctgt ctgaatacct gcaaacgctg
    19741 aaggccagcc atagtaatca tcaaggcaag taaaatgctc aatgtcctaa aatctatgta
    19801 accaatatac tgactatctg ggtgaacaac aaagctggat gccactgcca aaacgaaggc
    19861 taccactaat actatttcat ttcttataaa gttttttact gcttccatta atttatactc
    19921 cataatttaa ggcttggcac ttggccaagc cctataatac tataattctc tagatctttc
    19981 tatgcagata cgctcagctt caataactgc gcttctaaaa ccaagtgatt caagagctgt
    20041 aaccgcctct atagtagtgc ctcctggtga gcaaacatta tcctttagca ctcctgggtg
    20101 ctctcctgtt tcaaggacca tctttgctga accaagaact gcctgtgccg caaacttgta
    20161 agcctgtgct cttggcatgc cctctgcaac tgcaccatct gcaagtgcct caataaacat
    20221 atatacataa gctggagatg agccgctgat accaacaacc gcatcctgta atttttcagg
    20281 aaccacctct gcctttccga aggattcaaa gagctcaact actatctcgc actcttcttc
    20341 tgttacatgc tcatttggac taagagcact cattgcctcg ccaacaagag ctggtgtgtt
    20401 aggcataaca cgaataagct taagatctgt tccaaaaaga cttctcaatc tatctaagga
    20461 ctggcctgct gcaatactta caacaacctt gtcactaaaa tccatatcct ttattccttc
    20521 gatagcatca ggaagatact gaggctttac cgcaagaata actatatctg cgaaatcaac
    20581 tacatccctg ttgctaatac tggtgttaac accaaactct tcactaagct cgtctaaagt
    20641 agcctgaaaa atatcgctag ccattacatc ctggggctct actgtaccgg atgaaattac
    20701 tccaccaatc atagaactac ccatgttacc tgcgccgata aaaccaatct tcatgttttc
    20761 ctccttgcaa tcaaaaaagc cctataacaa cacactaagt gtatcatttt agaattattc
    20821 tgtacattca tttttccttg tttttgtagg tagtagagca aatcaagtag caaaatatat
    20881 aaaatttccc tccaaaaatt ggaatgcaat cattggtgct aatagtaaca ccacatttgg
    20941 attccaggga tcaggtgaaa ttggtgatgt tattgaatat gttttatatt cttgctcccc
    21001 cgctggcact acttgtaatc aagtttttta tcagatataa tccaataaat atcgtaaata
    21061 cgaagcacaa ataggagaca agatgaaatt attcagccaa tataagggtt tacgtagagc
    21121 taattacata ctgtttatag gtcgaattgt caccaatatg ggtgccatga tttggcctat
    21181 gctaacactt attcttaata agaaaattgg gttcaatgcc actgaaactg cgctttttac
    21241 tatttgctct ggcattttat ttttacctgc aaatcttttg ggtggacatg tggctgacag
    21301 gttcaataag aagcatgtca ttatttactg tgacattgtg tctattgttt tatttgtcat
    21361 cagtggtttc ctgcctcttt caatattctc catctgcgta ctgttggtag gcgctttttt
    21421 ccagactttg gaaggccctg catatcaggc tctggttgct gatattacac ctgcagaaaa
    21481 aagagaaaaa gcattttctt tattatattt aggagccaat atcggactta tcctctcgcc
    21541 tacattagct ggattgcttt ttaataatta tctctggctg tgttttgtaa tcagtggtct
    21601 gtctatcagt gtatcaacag tattaattgg actgttcgta aaagatgaaa agctggagga
    21661 agctcctaca gaggatgtag aagaatccgc tgacgatggc ctaaacatct ggagcattat
    21721 cagaaatagc ggtgcgctaa ttgcctttat catctctttg gcattttatc agggcgcgta
    21781 ctctcaattt ggatacctta tgcctttaga catagcaaaa gcctttccgg agaaaggctc
    21841 tataatatat ggaactatca ctagtgtaaa ctgtttctta gtagttttgt ttacacctat
    21901 tatcacaatg atttttgaaa aggttgatct aaccaaaaaa ttcgccttag gtgtaatcct
    21961 tcaggctatc agctttgcag catttttaat gtccttcggt atcatcggag gatactatat
    22021 ttctatcgcc ctcttcacct tcggcgaaat cctcaccact atcatgatgg gagctttcct
    22081 agccgaacgt gtaccagaga gccaccgcgg acgtatcttt ggagtaacaa acttcgccgg
    22141 tgcttttatg cagggcatca cacagttcgg cagcggaaga atgtttgacg ccttcggccc
    22201 ttcatacgcc tgggcattct ccattgctat gactatggtt gctgttattg cggcactgat
    22261 gcttgtatac ttagacaaaa aagagtttag ccagctgtat gtacaggctg actaaactca
    22321 tcatcttacg tatttgatta ctgcactttt ctatttcctg caaggacctc tttatagtcc
    22381 tccag
//
