LOCUS       NZ_FNDV01000005        10375 bp    DNA     linear   CON 11-JAN-2024
DEFINITION  Actinokineospora alba strain CPCC 201030, whole genome shotgun
            sequence.
ACCESSION   NZ_FNDV01000005
VERSION     NZ_FNDV01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora alba
  ORGANISM  Actinokineospora alba
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/11/2024 04:12:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,588
            Genes (coding)                    :: 6,533
            CDSs (with protein)               :: 6,533
            Genes (RNA)                       :: 79
            rRNAs                             :: 4, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 14 of 55
            Pseudo Genes (incomplete)         :: 41 of 55
            Pseudo Genes (internal stop)      :: 4 of 55
            Pseudo Genes (multiple problems)  :: 4 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:41:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2342
            Orig. end                         :: 12717
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNDV01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10375
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10375
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10375
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:5375](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5375)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    397..417
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.11"
                     /tool="antismash"
     gene            complement(528..1253)
                     /locus_tag="BLR56_RS16470"
                     /old_locus_tag="SAMN05421871_1053"
     CDS             complement(528..1253)
                     /NRPS_PKS="Domain: Thioesterase (9-219). E-value: 4.1e-31.
                     Score: 101.1. Matches aSDomain:
                     nrpspksdomains_BLR56_RS16470_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="BLR56_RS16470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1053"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_091374117.1"
                     /sec_met_domain="Thioesterase (E-value: 1.2e-28, bitscore:
                     95.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSATDPPFRLVCLPPAGGSAATFKPWVAGLGPEFAVDAVDVRGR
                     AGSLVEVAADLAHSIAAPGRYALVGHSLGGLLAFEIAKRIADSGLPAPEFAVVAGSRPP
                     HRSSSRVFAPLLSLDDDRLIDALASMGAVNPLLRKSPLRGLFMPALRADLELIVGYSGP
                     AEAVSVPLVAWHGVDDPLASPALGLEWARYAAAGFTHAAVEGGHFFLYERVSVVRGLLR
                     QLVGLPVAGTSGGRFPIGA"
     aSDomain        complement(597..1226)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLR56_RS16470_Thioesterase.1"
                     /evalue="4.10E-31"
                     /label="BLR56_RS16470_Thioesterase.1"
                     /locus_tag="BLR56_RS16470"
                     /protein_end="219"
                     /protein_start="9"
                     /score="101.1"
                     /tool="antismash"
                     /translation="RLVCLPPAGGSAATFKPWVAGLGPEFAVDAVDVRGRAGSLVEVAA
                     DLAHSIAAPGRYALVGHSLGGLLAFEIAKRIADSGLPAPEFAVVAGSRPPHRSSSRVFA
                     PLLSLDDDRLIDALASMGAVNPLLRKSPLRGLFMPALRADLELIVGYSGPAEAVSVPLV
                     AWHGVDDPLASPALGLEWARYAAAGFTHAAVEGGHFFLYERVSVVRG"
     CDS_motif       complement(1002..1064)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLR56_RS16470_0001"
                     /evalue="7.60E-10"
                     /label="NRPS-te1"
                     /locus_tag="BLR56_RS16470"
                     /protein_end="84"
                     /protein_start="63"
                     /score="31.2"
                     /tool="antismash"
                     /translation="GRYALVGHSLGGLLAFEIAKR"
     gene            complement(1237..2445)
                     /gene="metK"
                     /locus_tag="BLR56_RS16475"
                     /old_locus_tag="SAMN05421871_1054"
     CDS             complement(1237..2445)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439983.1"
                     /locus_tag="BLR56_RS16475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1054"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_143025296.1"
                     /transl_table=11
                     /translation="MSAPASRLFTSESVTEGHPDKICDAISDAVLDAMLAKDPVSRVAV
                     ETMVTTGQVHVVGEVTTEAYADIPGIVRDRILDIGYDSSAKGFDGRSCGVNVAIGAQSP
                     DIARGVDTAHEVRADAADDDDEIGRQGAGDQGLMFGYACTDTPELMPLPIALAHRLALR
                     LTAVRKSGVMPYLRPDGKTQVTIDYEGDRPVRVDTVVVSSQHAEGVSLTGLLGPDVQEH
                     VVDPELAALGLDSAGMRLLVNPTGRFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNAVAAGLASRVEVQVAYAIGKAAPVGLFVETFGTETVDP
                     ARIQSAIREVFDLRPGAIIRDLDLLRPIYAQTAAYGHFGRPDLDLPWERTDRVTALRDV
                     LGH"
     gene            complement(2442..3152)
                     /locus_tag="BLR56_RS16480"
                     /old_locus_tag="SAMN05421871_1055"
     CDS             complement(2442..3152)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012444.4"
                     /locus_tag="BLR56_RS16480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1055"
                     /product="indole-3-glycerol phosphate synthase"
                     /protein_id="WP_091374114.1"
                     /transl_table=11
                     /translation="MSRFIDTLVTAARPLIMEVKRRDPHGADLMGGRSVAEVVAAYELA
                     DAACVSVVTGHWFGGTPDLLREVADLTDKPVLQKDFITRTEHLKRARAGGASAVLLTAG
                     LLSKSSLANLIDAALSLELTPFVEVTDESEVDTIVHPADCVIAVNNKDIKIAERDTADL
                     SRSERMLPALLGAGTLAPVSASGIDTPRTATGLLGIGYAGLLVGTALLRAPSVADWLDE
                     FDNARKLAMEGTSR"
     gene            complement(3149..3847)
                     /locus_tag="BLR56_RS16485"
                     /old_locus_tag="SAMN05421871_1056"
     CDS             complement(3149..3847)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012900.4"
                     /locus_tag="BLR56_RS16485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1056"
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="WP_091374111.1"
                     /transl_table=11
                     /translation="MNAGLLKICGATTTDEVDLLAAAGADLVGLWHGVPGGRAELSLDR
                     TAELAAAARSTGVSRPMLVTFLSDPERLAEVLERTGIEWVQLHAYQSPSVVRALRESVP
                     SGVTIVKVLHLADDGCVERRLIPAYERAGTDVFLFDRVGADGRVGSTGVRLPEAAVADL
                     VPRLNRQFLLAGGITAGNRVDYPWLTAQPGFLGIDVDTAARDERGQFDANAVAAIAVGW
                     GTKRAREVVG"
     gene            complement(3844..4983)
                     /locus_tag="BLR56_RS16490"
                     /old_locus_tag="SAMN05421871_1057"
     CDS             complement(3844..4983)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680898.1"
                     /locus_tag="BLR56_RS16490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1057"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_091374108.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.8e-20, bitscore:
                     66.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8e-27, bitscore:
                     88.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.7e-31, bitscore:
                     104.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEWNADQTALRAGLAQWCAALSADHVERDEAGEFSWDCWKLVRQ
                     SGILGLPFDEQWGGLGQDLITTMGVLEALGEGNRDGGLSFCVTTSMASTGVPLEAFGTV
                     EQRSRYLPGICSGELIGAHAITESEGGSDALNMLTTARRDGDVFVLNGSKTFVSNGPIA
                     DVIVVYAKTRHNAGPLGITALLVDRDTPGLSVGRPMKKMGLRTSPISELFFDDCRIPAT
                     QVLGRVGGGFLVLDHVMKREILFSFIVNVGEMRHRLNRCLAYAKSRKQFGQAIGSNQAI
                     ANKLVDMRIRVATARKWLYDTAERLVAGHNVTTDLAIAKLLTSEGNLASSLTAVQIFGG
                     HGYMAETGLEKDVRNAVAGTIYSGTTEIQYNRVAAMMGL"
     gene            complement(5001..5375)
                     /locus_tag="BLR56_RS16495"
                     /old_locus_tag="SAMN05421871_1058"
     CDS             complement(5001..5375)
                     /GO_function="GO:0033990 - ectoine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559775.1"
                     /locus_tag="BLR56_RS16495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1058"
                     /product="ectoine synthase"
                     /protein_id="WP_091374096.1"
                     /sec_met_domain="ectoine_synt (E-value: 8.3e-33, bitscore:
                     108.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIRELADVRTVDWGNGLSRRFLVESDGMGYTLTDTIVRAGTKSR
                     LEYRNHLEACYCVEGSGEVVDMEGTSHPITPGVLYALDKHDAHFLIASPHEDLRLVCVF
                     SPALRGDEVHSLDGAGFSHY"
     gene            complement(5375..6262)
                     /gene="trpA"
                     /locus_tag="BLR56_RS16500"
                     /old_locus_tag="SAMN05421871_1059"
     CDS             complement(5375..6262)
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: protein motif:HMM:TIGR00262.1"
                     /locus_tag="BLR56_RS16500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_1059"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_091374090.1"
                     /transl_table=11
                     /translation="MGDARGSGPEVAVFAGGAGASASLVGPFFGQRPAGVPGLALFLNA
                     GDPPLDVLADLVVMLDESGVDCLELAVPFPGSVTDGPTVRASADRALAQGVDLDATLAF
                     IARVRPSLRRLRIALLVDWSHSLKRRPLSTVADEVAAAGVDGLLVHGLPPRLRAEYYQA
                     THALPIVTTCYHRVSSPEVLAEAAAKATAYVYLVAHYGRSGSAPAAGYAELAGTVARLR
                     ATASAPIAVGFGVRTRDDVEAIHRCGADAVIVGSAGVAVVESALARGRDVVADFGGFAR
                     SLRPSTITLSTGST"
     gene            complement(6439..7446)
                     /locus_tag="BLR56_RS16505"
                     /old_locus_tag="SAMN05421871_10510"
     CDS             complement(6439..7446)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012800.4"
                     /locus_tag="BLR56_RS16505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_10510"
                     /product="hypothetical protein"
                     /protein_id="WP_091374089.1"
                     /transl_table=11
                     /translation="MHEVITTLLRGRGSVDVPAWRGLWERLDAGELDRAEIAALLATLC
                     AELPDRDTLVALVVSLRRPAEPVLAGAVNIVGTGGGPGTFNISTAAAFTAAAMGVPVVK
                     TGSRAYTGAVGSIDLLERLGVRLTKSPAETVDALGRFGIAFTGPYVYPLALTRMARTLV
                     PLAMRPFGRFLNAIGPFLAAVPVTAQVTGVSAAAPLARLRELSAVLHDRRIWLCANDQG
                     ADELLGFAHNVIHPNDGTGPISLSPGVLAAGTGGLADLAPATEVTTHFLDVLAGKAGAA
                     ATEAVCLNAAALAVAGGRHPTWPEAYKAAETAIHDGAARSLADRLRTATAVLRG"
     misc_feature    7442..7455
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            complement(7449..7712)
                     /locus_tag="BLR56_RS16510"
                     /old_locus_tag="SAMN05421871_10511"
     CDS             complement(7449..7712)
                     /NRPS_PKS="Domain: PP-binding (18-71). E-value: 4.2e-07.
                     Score: 22.2. Matches aSDomain:
                     nrpspksdomains_BLR56_RS16510_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680900.1"
                     /locus_tag="BLR56_RS16510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_10511"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_091374087.1"
                     /sec_met_domain="PP-binding (E-value: 2.7e-07, bitscore:
                     25.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.0031, bitscore:
                     12.5, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVAAIKAFIIEEFLPDVAAASLQVDYDLLAGGVIDSLGLLKLI
                     AWVEDRFSVPIGDEDLDPDNFRSVSAIDRFVDTARVGPAVGA"
     aSDomain        complement(7500..7658)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLR56_RS16510_PP-binding.1"
                     /evalue="4.20E-07"
                     /label="BLR56_RS16510_PP-binding.1"
                     /locus_tag="BLR56_RS16510"
                     /protein_end="71"
                     /protein_start="18"
                     /score="22.2"
                     /tool="antismash"
                     /translation="VAAASLQVDYDLLAGGVIDSLGLLKLIAWVEDRFSVPIGDEDLDP
                     DNFRSVSA"
     gene            complement(7709..9172)
                     /locus_tag="BLR56_RS16515"
                     /old_locus_tag="SAMN05421871_10512"
     CDS             complement(7709..9172)
                     /NRPS_PKS="Domain: AMP-binding (12-384). E-value: 1.8e-69.
                     Score: 226.2. Matches aSDomain:
                     nrpspksdomains_BLR56_RS16515_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646416.1"
                     /locus_tag="BLR56_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_10512"
                     /product="AMP-binding protein"
                     /protein_id="WP_091374351.1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-63, bitscore:
                     207.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPNIESLADGFARQARCRPDAPALVWHDTEITYGELSAMAAAE
                     RARLDGLGLAPGVPVGVLAEKSPEAVALVLAGLLARRPVLLPSPALADSVLTTLFTQAG
                     CATVVAPLGQVPRVSITASAHPDIPADTALLLTTSGSTGLPKIVPLGGQAMARFADWAA
                     PTFGIGPGRSVLSVAPLNFDLCLLDVWTTLAAGGRVVLVDPARAANGRHLAEVLRSNRP
                     HVVQAVPMFFALLMAAGAGGFDSVEHVMLTGDATPEHVLAGMPALFPKARLRNIYGCTE
                     TNDSLMSDVDSSPISIGDPLPGVSALLVDDGEVVRGSGTGELWVSTPFQTEGYLDRTRH
                     TGKFAGHPTGANDRRYFRTGDLVRRGVDGRLFLVGRADFQVKVRGVAVNTAEVEHALLE
                     HPDVLEAAVAAVPDPVAGLKLAAAVHRAPGSRLDSVVLREHCVRTLPRAAIPSTLRIAD
                     DPLPKTATGKVDRTAVGGRPQSTVERRVS"
     CDS_motif       complement(7991..8053)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLR56_RS16515_0002"
                     /evalue="3.60E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="BLR56_RS16515"
                     /protein_end="394"
                     /protein_start="373"
                     /score="22.6"
                     /tool="antismash"
                     /translation="VGRADFQVKVRGVAVNTAEVE"
     aSDomain        complement(8021..9136)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLR56_RS16515_AMP-binding.1"
                     /evalue="1.80E-69"
                     /label="BLR56_RS16515_AMP-binding.1"
                     /locus_tag="BLR56_RS16515"
                     /protein_end="384"
                     /protein_start="12"
                     /score="226.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FARQARCRPDAPALVWHDTEITYGELSAMAAAERARLDGLGLAPG
                     VPVGVLAEKSPEAVALVLAGLLARRPVLLPSPALADSVLTTLFTQAGCATVVAPLGQVP
                     RVSITASAHPDIPADTALLLTTSGSTGLPKIVPLGGQAMARFADWAAPTFGIGPGRSVL
                     SVAPLNFDLCLLDVWTTLAAGGRVVLVDPARAANGRHLAEVLRSNRPHVVQAVPMFFAL
                     LMAAGAGGFDSVEHVMLTGDATPEHVLAGMPALFPKARLRNIYGCTETNDSLMSDVDSS
                     PISIGDPLPGVSALLVDDGEVVRGSGTGELWVSTPFQTEGYLDRTRHTGKFAGHPTGAN
                     DRRYFRTGDLVRRGVDGRLFLVGRADFQVKVR"
     CDS_motif       complement(8726..8776)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLR56_RS16515_0001"
                     /evalue="6.10E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="BLR56_RS16515"
                     /protein_end="149"
                     /protein_start="132"
                     /score="12.8"
                     /tool="antismash"
                     /translation="ALLLTTSGSTGLPKIVP"
     misc_feature    complement(8771..8773)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9165..10010)
                     /locus_tag="BLR56_RS16520"
                     /old_locus_tag="SAMN05421871_10513"
     CDS             complement(9165..10010)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013722.4"
                     /locus_tag="BLR56_RS16520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_10513"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_091374085.1"
                     /transl_table=11
                     /translation="MTAAPTRFGASDLCAVTAAELAAYRDVLRSAIGSPLPAGVPQASP
                     VYPFVLAMPTFDQIIGQLTPAGEARAANVHLSQELRVRRLVQPGERVGIDVVVAAARRE
                     PRGVRLAIRGVVVGDGGAVVAELITGALLVGATGPEPFGDLPPATELAAGPGPSERTSV
                     TCVIPAETVRAYADVSGDHNPIHLDEAAATAAGFPGVIAHGMSVLALISEDVIDRYAGG
                     DASRIGGLGVRFSAPVLPEEPLEITYVTDGGPVVKFTCKSPRGLAFKAGWVEISGDRDG
                     "
ORIGIN
        1 ccgcgttcca ccctccgccg tgcacccaca ccactgcggg gcgaggcccc gacgccgagc
       61 cggcgggcac cttcacatcc agcttgagcg cctgcccatc gacctcgttg tagaccacgg
      121 tcaccgcgtc gaccggtttg ccggtgttct cgccgccttc gaagtagtcc ccgagggaca
      181 ggtccgcgcc gtagcggtcg gcggcccggt aggtggccac cagcgggacg cagatcgcca
      241 ccgtggccgc caaagccacc acacctgtga ccgcgccgac cttccgcgcg cccacccgga
      301 aagccaccca agccaacgcg acaccgatca tcccgagcgg cacgacgtga acgcccttgt
      361 tgctcacaat ctccgagacc cgcaccaacg actccggtat cgacgcggag acgatcacga
      421 acgccacgat cgccagcaac accgcgacga cgacggcgag cacggccgcc acgacccgac
      481 gggtcgtcac gggcttgctc cgggaatcct gggtcacgcc cgaagtctca cgcgccgatc
      541 ggaaaccgtc cacccgacgt cccggccacg gggagtccga ccagctgccg gagcaacccc
      601 cgaaccacgg aaacccgctc atacaagaag aagtgccctc cttcgacagc cgcgtgcgtg
      661 aagcccgccg ccgcgtatcg cgcccactca agccccaatg caggcgaggc caacgggtca
      721 tccaccccat gccaggcgac caggggcacc gacacggcct cagcaggccc cgaatagccc
      781 acgatcaact caaggtccgc ccgcaacgcg ggcatgaaca gcccacgcag cggcgacttc
      841 cgcagcagcg gattcaccgc gcccatcgac gccagcgcgt cgatcaggcg gtcgtcgtcc
      901 agtgacagca gcggcgcgaa cacccgcgac gacgaccggt gcggcggccg cgaccccgcc
      961 accacggcga actccggcgc gggcagcccc gagtcggcta tccgcttggc gatctcgaac
     1021 gccagcagcc caccaaggct gtgccccacc agcgcgtacc gccccggcgc ggcgatcgag
     1081 tgcgccaggt ccgccgccac ctccaccagc gagccggcgc ggccacggac gtcgaccgcg
     1141 tccaccgcga actccgggcc caggcccgcc acccacggct tgaaggtcgc cgccgacccg
     1201 cccgccgggg gcaggcagac gagtcggaac ggcgggtcag tggccgagga catcgcgcag
     1261 ggccgtgact cggtcggtgc gctcccacgg caggtcgagg tcgggtcggc cgaagtggcc
     1321 gtaggccgcg gtctgcgcgt agatcggccg cagcaggtcc aggtcgcgga tgatcgcacc
     1381 ggggcgcagg tcgaacacct cgcggatcgc ggactggatc ctcgccgggt cgacggtctc
     1441 ggtcccgaac gtctcgacga acagcccgac cggcgccgct ttgccgatgg cgtaggcgac
     1501 ctgcacctcg acccgcgaag ccaggcccgc ggccacggcg ttcttcgcga cccagcgcat
     1561 cgcgtacgcc gccgagcggt cgaccttcga cgggtccttg ccggagaacg cgccgccgcc
     1621 gtgccgcgcc atgccgccgt aggtgtccac gatgatcttg cgtccggtga ggcccgcgtc
     1681 gcccatcggg ccgccgatga cgaaccggcc ggtggggttg accagcagcc gcatgcccgc
     1741 gctgtcgagc cccagggccg cgagttcggg gtcgaccacg tgctcctgga cgtcggggcc
     1801 gagcaggccc gtgaggctga ctccctcggc gtgctgggac gacacgacga cggtgtcgac
     1861 gcggaccggc cggtcgccct cgtagtcgat ggtgacctgg gtcttcccgt cgggccgcag
     1921 gtacggcatg acaccggact tgcgcaccgc ggtcagccgc agcgccagcc ggtgggccag
     1981 ggcgatcggc agcggcatca gctccggcgt gtcggtgcac gcgtagccga acatcaggcc
     2041 ctggtcgccc gcgccctgcc tgccgatctc gtcgtcatcg tcggccgcgt cggcgcggac
     2101 ctcgtgggcg gtgtcgacgc cgcgcgcgat gtccggggac tgggcgccga tggccacgtt
     2161 caccccgcac gaccggccgt cgaacccctt ggccgacgag tcgtagccga tgtccaggat
     2221 gcggtcgcgg acgatgcccg ggatgtcggc gtaggcctcc gtcgtgacct cgccgacgac
     2281 gtggacctgg ccggtcgtca ccatggtctc cacggccacc ctggacacgg ggtccttggc
     2341 gagcatggcg tcgaggaccg cgtcgctgat ggcgtcgcag atcttgtccg ggtggccctc
     2401 cgtcaccgat tcggaggtga acaaccggct ggctggcgcg ctcatcgtga ggtcccttcc
     2461 atggcgagtt tccgggcgtt gtcgaactcg tcgagccagt cggcgacgct gggggcgcgc
     2521 agcagggcgg tgccgacgag caggcccgcg tagccgatgc cgagcagccc ggtggcggtc
     2581 cgcggggtgt cgatgccgct ggcgctcacc ggcgccaagg tgccggcgcc gagcaacgcg
     2641 gggagcatcc gttcgctgcg gctgaggtcg gcggtgtcgc gttcggcgat cttgatgtcc
     2701 ttgttgttga cggcgatgac gcagtccgcc gggtggacga ttgtgtccac ttcggactcg
     2761 tcggtgacct cgacgaacgg ggtcagctcc agcgacagcg ccgcgtcgat caggttggcc
     2821 aggctggact tgctgagcag gcccgccgtg agcagcacgg ccgacgcgcc gcccgcgcgg
     2881 gcgcgcttga gatgttcggt gcgggtgatg aagtccttct gcagcaccgg tttgtccgtc
     2941 aggtcggcga cttcgcggag caggtcgggg gttccgccga accagtggcc ggtgacgacg
     3001 gagacgcagg ccgcgtccgc gagctcgtag gccgcgacga cctcggcgac cgagcggccg
     3061 cccatcaggt ccgcgccgtg cggatcgcgg cgtttgacct ccatgatcaa agggcgggcc
     3121 gccgtcacca gggtgtcgat gaaccggctc atccgaccac ctcccgagcc cgtttcgtac
     3181 cccacccgac cgcgatggcc gcgaccgcgt tcgcgtcgaa ctggccacgt tcgtcacgcg
     3241 cggccgtgtc cacgtcgatg ccgaggaagc cgggctgcgc ggtcagccac gggtagtcga
     3301 ctcggttgcc cgcggtgatg ccgcccgcga gcaggaactg ccggttcagc cgcgggacca
     3361 ggtcggccac ggcggcctcg ggcaaccgca ccccggtgct gccgacccga ccgtccgcgc
     3421 cgacccggtc gaacaggaac acgtcggtcc ccgcgcgttc gtaggccggg atcaggcgtc
     3481 gctcgacgca gccgtcgtcg gcgagatgga ggaccttcac gatcgtcact ccacttggca
     3541 cagactcccg aagcgcgcgg acgaccgacg gggattggta cgcgtgcagt tgcacccact
     3601 cgattcccgt gcgctccaac acttccgcca gacgttcggg atcgctcagg aacgtcacca
     3661 gcatcggccg tgacacaccg gtcgagcgtg cggcggcggc aagctcggcg gtccggtcga
     3721 gcgagagttc ggcgcgcccg cccggcacac cgtgccagag tccgacgagg tcggcgccag
     3781 cggctgcgag caggtcgacc tcgtcggtcg tggtcgcgcc gcagatcttg agcaggccgg
     3841 cgttcatagg cccatcatcg ccgcgactcg gttgtactgg atttccgttg tgccggaata
     3901 gatcgtgccc gcgaccgcgt tgcgcacgtc cttctccaac ccggtctcgg ccatgtagcc
     3961 gtggccgccg aagatctgca ccgcggtcag gctggaggcg aggtttccct cgctggtcag
     4021 cagtttggcg atcgccagat cggtggtgac gttgtggccc gcgaccagcc gctcggcggt
     4081 gtcgtagagc catttgcggg cggtggcgac ccggatgcgc atgtcgacga gcttgttcgc
     4141 gatggcctgg ttggacccga tggcctggcc gaactgcttg cgggacttgg cgtaggccag
     4201 gcagcggttg agccggtggc gcatctcccc cacgttgacg atgaaggaga acaggatctc
     4261 gcgcttcatc acgtggtcga gcaccaggaa cccgccaccc acccgaccga gcacctgggt
     4321 ggcggggatc cggcagtcgt cgaagaacag ctcgctgatc ggcgaggtgc gcaaacccat
     4381 cttcttcatg ggtctgccca cgctcagacc gggggtgtcc cggtccacga gcagcgcggt
     4441 gatgccgagc ggaccagcgt tgtggcgggt cttcgcgtag acgacgatga cgtcggcgat
     4501 cggtccgttg ctcacgaaag tcttgctgcc gttgagaacg aacacgtctc cgtcgcgtcg
     4561 cgccgtggtg agcatgttca gcgcgtccga cccgccttcg gattcggtga tcgcgtgggc
     4621 gccgatcagc tcaccggaac agatacccgg caggtagcgg ctccgctgct ccacggtgcc
     4681 gaaggcctcc aggggcacac cggtgctggc catgctggtg gtcacgcaga aactcaggcc
     4741 gccgtcgcgg ttgccctcgc ccagcgcctc cagcacgccc atggtggtga tcaggtcctg
     4801 gccgagcccg ccccactgtt catcgaacgg caggccgagg atgcccgact ggcgtaccag
     4861 tttccaacag tcccaggaga actcgcctgc ctcgtctcgt tccacgtggt cggcgctgag
     4921 cgccgcacac cactgcgcca gtcccgcgcg cagtgcggtc tgatcggcgt tccactcgat
     4981 caccgcgaca ccgccttcgg tcagtagtgg gagaaaccgg ccccgtcgag gctgtgcacc
     5041 tcgtcgccgc gcagggcggg cgagaacacg cacaccagtc gcaggtcctc atgcggactg
     5101 gcgatcagga aatgcgcgtc gtgcttgtcg agcgcgtaga ggacacccgg ggtgatcggg
     5161 tgcgaagtgc cttccatgtc gacgacctcg cccgacccct cgacgcagta gcacgcctcg
     5221 aggtggttgc ggtactccag ccgggacttg gtgcccgcgc ggacgatggt gtcggtcagg
     5281 gtgtagccca tgccgtcgga ctcgacgagg aagcgcctgc tcaggccgtt gccccagtcg
     5341 acggtgcgga cgtcagcgag ctcacggatg atcatcatgt actccctgtg ctgagggtga
     5401 tggtggatgg gcggagggac cgggcgaacc cgccgaagtc ggcgaccacg tcccggccgc
     5461 gcgccaaggc gctctccacc acggcgaccc cggcggaccc gacgatgacc gcgtcggccc
     5521 cgcaccggtg gatcgcctcg acgtcgtcgc gggtgcgaac gccgaagccg accgcgatcg
     5581 gcgccgaggc cgtcgcgcgc aggcgggcga cggtgcctgc cagctcggcg tagcccgccg
     5641 cgggcgcgga accgctgcgc ccgtagtggg ccaccaggta cacgtaggcc gtcgccttcg
     5701 ccgcggcctc ggccagcacc tccggggagg agacccggtg gtagcaggtg gtcacgatgg
     5761 gcagcgcatg ggtggcttgg tagtactcgg ccctgagcct cggtgggagg ccgtgcacca
     5821 acaggccgtc gacaccggcg gcggcgacct catcggccac tgtggacagt ggacggcgct
     5881 tgagggagtg gctccagtcg accagcagcg caatccgcag cctgcgcaga ctcgggcgga
     5941 ccctagcgat gaaggcgagg gtggcgtcga ggtcgacacc ttgggccagg gcgcggtcgg
     6001 cggaggcgcg aacggtgggg ccatcggtga cggaaccggg aaaggggacc gccagctcca
     6061 gacagtccac accggactcg tcaagcatga cgacgagatc ggcgaggacg tcgagcggcg
     6121 gatcaccggc gttgaggaag agcgcgagac cggggacacc tgcgggccgc tgaccgaaga
     6181 acggcccgac aagacttgcc gaagcaccgg caccacctgc gaaaacagct acttcaggcc
     6241 cagaacctcg ggcatcgccc acccacgcgc agcccccacc ctgtcccggg gggacggccc
     6301 ttggccagtc tatcgggggt ggaggggtgg tggaagggtg tgcggaatgc tgtggatgcc
     6361 ttggtggggt tggggataac tcaggcactg ggcaccgccg cggtggtagt gcgagcagga
     6421 agccggggac aggtcatttc agccacggag caccgccgtg gcggtgcgga ggcggtcggc
     6481 cagggagcgg gcggcgccgt cgtggatggc ggtttccgcg gccttgtacg cctccggcca
     6541 ggtgggatgc ctgccgcctg cgacggccaa ggcggcggcg ttcagacaga ccgcctccgt
     6601 ggcggcggcg cctgccttgc ccgccaggac gtcgaggaag tgggtggtca cctcggtcgc
     6661 cggtgccagg tcggccaagc caccggttcc ggccgccagc accccgggcg acaggctgat
     6721 gggacccgtg ccgtcgttgg ggtggatgac gttgtgggcg aagccgagca gttcgtcggc
     6781 gccctggtcg ttggcgcaga gccagattcg gcggtcgtgc aggacggccg acagctctcg
     6841 gaggcgggcc agtggggcgg ccgcggacac acccgtcacc tgggcggtca ccgggaccgc
     6901 ggccaggaac ggcccgatgg cgttgaggaa gcggccgaag gggcgcatcg ccaggggcac
     6961 cagggttcgg gccatccggg tgagcgcgag cgggtagacg tacgggccgg tgaaggcgat
     7021 gccgaaccgg cccaaggcgt cgactgtttc cgccggggac ttggtcagcc gcacccccag
     7081 ccgttccagc aggtcgatcg acccgaccgc gcccgtgtag gcccgcgaac cggtcttcac
     7141 caccggcacc cccatcgccg cggcggtgaa cgccgcggcg gtggagatgt tgaaggtgcc
     7201 ggggccgccg ccggtgccga cgatgttgac cgcgcccgcc aggaccggct cggcgggccg
     7261 gcgcagcgag accaccaagg cgacgagtgt gtcccggtcg ggcagctccg cgcacagggt
     7321 ggcgagcagg gcggcgatct cggcccggtc gagctcgccc gcgtccaggc gctcccacag
     7381 cccgcgccag gcggggacgt cgaccgagcc ccgcccgcgc agcagggtcg tgatcacctc
     7441 gtgcatggtc aggcacccac cgcgggcccg acgcgcgcgg tgtcgacgaa gcggtcgatg
     7501 gcgctgacgc tgcggaagtt gtcggggtcg aggtcctcgt cgccgatcgg gacgctgaac
     7561 cggtcctcga cccaggcgat gagcttgagc aggcccaggc tgtcgatcac acccccggcg
     7621 agcaggtcgt agtccacctg cagggacgcg gcggcgacgt cgggcaggaa ctcctcgatg
     7681 atgaacgcct tgatcgcggc gacgttgctc atgacaccct tctttccact gtggactggg
     7741 gacggccgcc gaccgcggtg cggtcgacct ttccggtggc ggtcttgggg agcgggtcgt
     7801 cggcgatgcg cagggtcgac gggatcgccg cccgcggcag ggtgcgcacg cagtgctcgc
     7861 gcagcacaac gctgtccagg cggctgccgg gcgcgcggtg gacggcggcg gcgagcttga
     7921 ggcccgccac cgggtcgggc accgcggcga cggccgcctc cagcacgtct gggtgttcga
     7981 gcagggcgtg ttcgacctcg gcggtgttga ccgcgacccc gcgcaccttc acctggaagt
     8041 ccgcgcgccc caccaggaac agcctgccgt cgaccccgcg gcgcaccagg tcgccggtgc
     8101 ggaagtaccg gcggtcgttg gcgcccgtgg gatgtccggc gaacttgccg gtgtgccggg
     8161 tccgatccag gtacccctcg gtctggaacg gtgtggagac ccacaactcg cccgttccgg
     8221 acccccgtac cacttcgccg tcgtcgacca gcagtgcgct tacgccgggc agcgggtcgc
     8281 cgatcgagat cggcgacgag tccacatcgg acatgaggct gtcattggtc tctgtgcagc
     8341 cgtagatgtt gcgcagccgg gccttgggga acagcgcggg catcccggcc agcacgtgtt
     8401 ccggggtcgc gtcgccggtg agcatcacgt gctcgacact gtcgaagcca cccgcgcccg
     8461 cggccatcag cagcgcgaag aacatcggga cggcctggac gacgtgcggc cggttcgagc
     8521 gcagcacctc ggcgaggtgg cggccgttgg cggcgcgcgc cgggtcgacg aggaccaccc
     8581 ggccgcccgc ggccagcgtc gtccacacgt cgagcaggca caggtcgaag ttcagcggcg
     8641 cgacactcag caccgaccga cccggcccga tgccgaaggt cggcgccgcc cagtcggcga
     8701 accgagccat ggcctggccg cccagcggga cgatcttcgg caggccagtc gaccccgacg
     8761 tcgtcaagag taaggccgtg tcggcgggaa tatccgggtg agccgaggcc gtgatggaca
     8821 cccgcggcac ctgccccagc ggggccacca cggtcgcgca cccggcctgg gtgaacagcg
     8881 tggtgagcac cgagtcggcg agcgccggcg agggcagcag gaccggtcgc cgcgcgagca
     8941 aacccgccag caccagcgcc accgcctcgg gcgacttctc cgcgagcacc ccgaccggca
     9001 cgcccggcgc gaggccgaga ccgtcgagcc gcgcgcgttc ggcggcggcc atcgcggaga
     9061 gctcgccgta ggtgatctcg gtgtcgtgcc acaccagggc gggcgcgtca ggtcggcagc
     9121 gagcctgccg ggcgaacccg tcggcgaggc tctcgatgtt cggctcagcc atcgcggtca
     9181 ccggagatct ccacccagcc cgccttgaac gccaggccgc gcggggactt gcaggtgaac
     9241 ttcacgaccg ggccgccgtc ggtcacgtag gtgatctcca gcggttcctc gggcaggacc
     9301 ggcgcggaga accggacacc caggccgccg atccgggacg cgtcgccgcc cgcgtaccgg
     9361 tcgatcacgt cctcggagat cagcgcgagc acgctcatgc cgtgcgcgat caccccgggg
     9421 aacccggcgg cggtcgcggc cgcttcgtcg aggtggatcg ggttgtggtc gccggagacg
     9481 tcggcgtagg cgcgcacggt ctccgccggg atcacacagg tgaccgacgt ccgctcactc
     9541 ggccccggcc ccgcggccaa ctcggtcgcg ggcggcagat cgccgaacgg ctcaggaccg
     9601 gtcgcgccca ccaacagcgc gcccgtgatc agctcggcca ccaccgcgcc gccgtcgccg
     9661 acgacgacac cgcggatcgc cagccggacc ccgcgcggct cccggcgcgc ggccgccacg
     9721 acgacgtcga tgccgacccg ctcccccggc tgcaccagcc tgcgcacccg cagttcctgg
     9781 ctcaggtgca cgttcgccgc gcgggcctcg cccgccgggg tgagctgccc gatgatctgg
     9841 tcgaacgtgg gcatcgcgag cacgaacggg tacaccggcg acgcctgcgg aacccccgcg
     9901 ggcaacgggg acccgatcgc cgagcgcagc acgtcgcggt acgcggcgag ttcggcggcg
     9961 gtgacggcac acaggtcgct ggcgccgaac cgggtcggcg cggcggtcac ggggtcacca
    10021 ccagacaggc gttgtggccg ccgaagccga aggagttcga cagcgcggga ccactggcca
    10081 ccgcgcgtgg ctttccgtgc accaggtcga tgtccatgcc gggctcgatt cgttcgtggt
    10141 tggcggtcgg ggggacggtc cgggcggcca tggcgaggat cgtggcgatc aactcgaccg
    10201 tcccggcggc gccgatgagg tggccggtga cgcccttggt cgccgtcacc gggggcacgc
    10261 gggacccgaa gaccttggcc agggcgttcg cctcggcccg gtcgttgtgc ggggtcgacg
    10321 tgccgtgcgc gttgacatgc acgatgtcgg cgggcgtgag gcccgcgtcg gcgat
//
