LOCUS       NZ_FNDV01000001        21041 bp    DNA     linear   CON 11-JAN-2024
DEFINITION  Actinokineospora alba strain CPCC 201030, whole genome shotgun
            sequence.
ACCESSION   NZ_FNDV01000001
VERSION     NZ_FNDV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora alba
  ORGANISM  Actinokineospora alba
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/11/2024 04:12:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,588
            Genes (coding)                    :: 6,533
            CDSs (with protein)               :: 6,533
            Genes (RNA)                       :: 79
            rRNAs                             :: 4, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 14 of 55
            Pseudo Genes (incomplete)         :: 41 of 55
            Pseudo Genes (internal stop)      :: 4 of 55
            Pseudo Genes (multiple problems)  :: 4 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:41:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 320361
            Orig. end                         :: 341402
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FNDV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11041
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    502..516
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
     misc_feature    763..777
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    1068..1083
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    1615..1629
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    1944..1957
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(1945..1958)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.53"
                     /tool="antismash"
     misc_feature    complement(2222..2237)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            2464..4614
                     /locus_tag="BLR56_RS01475"
                     /old_locus_tag="SAMN05421871_101297"
     CDS             2464..4614
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="BLR56_RS01475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101297"
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_166657855.1"
                     /transl_table=11
                     /translation="MRHSEREQLINALATPARHADAAAMLRSLPKLGWLSARRAKRLRQ
                     AVLDALARDVPAWSIVAMLGGHDTEVVVAAMAPLVTDGPDPGMAAHLLLTALRTRPSDS
                     VSTQPRPDGGHWGQVDPPVRKRPRIPPREHIPPFVTERPNRDLTSGDPPSGGWGTGAWR
                     PPWLEQPSKHDPTRPVTPANPPDDVEPFEDFSPGPPSAREVWPTLECPASVDIDAQFDL
                     TVGIGPKQDMALLGTGPITLPNNMVRLEIVLMYDPTAFAPVGWSNPVVLTVDAENPYPV
                     ATLRMTALRGESLRSRRDIGASFYVDGGLRGYASRAIEVTGTPSGTVPLFGGAMLDIGP
                     LLKHEAPDLVVVVERGEDLRGQTLLWSTRSSVPGVASAPGPYRSEIGEDPAAFARRVRL
                     DVGAFGGDARGSTLKLIGVGRTIADHIPDEVCAALTAVSTARAPAPATVLLLSSEPHVP
                     WELAVLDPPPAEGSPFLGARMAIGRWVLARKRPRPTPPTEVRADRHIVVTARYEGVPGW
                     ARLPFAEAEAERLRLTYPPAVEVQPLHSAVLDCLEAGPDGGVLHFALHGKYDPENAQDG
                     LVLLAPSEANPDRLVPRFLQPDQVSAMAFSSAPFVFLNACQVGAAGEVLGDYSGLAKAF
                     LAAGAAGVVAPLWNVNDEAASALADAFYQDAYGPQALAPAEILRRARAEVSRDHYPTWP
                     ATTLAYQFFGHPRLRLRRDQGA"
     gene            4617..6089
                     /locus_tag="BLR56_RS01480"
                     /old_locus_tag="SAMN05421871_101298"
     CDS             4617..6089
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019436.4"
                     /locus_tag="BLR56_RS01480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101298"
                     /product="hypothetical protein"
                     /protein_id="WP_091370256.1"
                     /transl_table=11
                     /translation="MAEPLRPDGTEVRVGDVVVVSPGLTGQVEVLLPGTDGMRGAEDAR
                     LALLRALARCDFTEQLSVRVIDPVEVPELASGASRSTSLGEPAISVEVPGPGSGLGQVV
                     LAADEEGALSWHLPDDVPPDEVPSRGGDRRTYTFRRAVAPPAEPGGSRGLIGAVGSKLL
                     KVLVFPLIDPVLGKVGDHFAGRWEQKNRNVRLRDFVDHRVAEAGPVDWQALGAGPALLF
                     VHGTASQSHTGFHGVAPETLGTISARYGGRVFAFDHHTLSVDPVANARWLVEQIPAGAG
                     LTVDIVAHSRGGLVARALCELADEVGLTADRMTVRTLVMVATPNAGTPLCSPTNITAWL
                     DRMTNLLQWVPDNGLTDALDIVLTVAKQVAVGALRGLDGLMAMDPKGQFLVERLNKPAE
                     HTVTYRAVASNYDPVKGSGLLRSARNASTDVVFGLVPNDLVVPTEGVFAANGASAFPIA
                     EPQVFEAADGIDHSGFWPDARLVAALDRWLVG"
     gene            complement(6086..6826)
                     /locus_tag="BLR56_RS01485"
                     /old_locus_tag="SAMN05421871_101299"
     CDS             complement(6086..6826)
                     /NRPS_PKS="Domain: PKS_KR (4-165). E-value: 1.3e-17. Score:
                     56.2. Matches aSDomain:
                     nrpspksdomains_BLR56_RS01485_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005457318.1"
                     /locus_tag="BLR56_RS01485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101299"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_091370254.1"
                     /sec_met_domain="adh_short (E-value: 3.6e-30, bitscore:
                     101.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPLVILGGRSEIGVAVARRLVERGTRTVVLAARRSDDLDVEEST
                     LRAAGATTVERVEFDADDLASHEPLLAEITRAHGPIDTIVVAFGILGDQKVAERDSAHA
                     VRVVHTDYVAHVSVLTHIANLLRQQGNGIVVVFSSVAGVRVRRANYVYGSAKAGLDGFA
                     SGLADALHGSGVRLLLVRPGFVVGRMTDGMSPAPFSSTPDQVAAATVRALGGKRGEVWV
                     PAVLRPIFGIMRVLPRALWRKMPR"
     aSDomain        complement(6332..6814)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLR56_RS01485_PKS_KR.1"
                     /evalue="1.30E-17"
                     /label="BLR56_RS01485_PKS_KR.1"
                     /locus_tag="BLR56_RS01485"
                     /protein_end="165"
                     /protein_start="4"
                     /score="56.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VILGGRSEIGVAVARRLVERGTRTVVLAARRSDDLDVEESTLRAA
                     GATTVERVEFDADDLASHEPLLAEITRAHGPIDTIVVAFGILGDQKVAERDSAHAVRVV
                     HTDYVAHVSVLTHIANLLRQQGNGIVVVFSSVAGVRVRRANYVYGSAKAGLDGFASG"
     CDS_motif       complement(6722..6814)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLR56_RS01485_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BLR56_RS01485"
                     /protein_end="35"
                     /protein_start="4"
                     /score="18.1"
                     /tool="antismash"
                     /translation="VILGGRSEIGVAVARRLVERGTRTVVLAARR"
     misc_feature    complement(6979..6994)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            7108..8508
                     /locus_tag="BLR56_RS01490"
                     /old_locus_tag="SAMN05421871_101300"
     CDS             7108..8508
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685788.1"
                     /locus_tag="BLR56_RS01490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101300"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_091370252.1"
                     /transl_table=11
                     /translation="MTETVHPLNPARPEAAQQSLSTAAARNLATTTKSAPQMQEITSRW
                     LLRKLPWVQVTGGTYRVNQRRSYTVGDGRIAVDRSGATARVVAGDLRELACLRDFEDED
                     VLGALAGLFTQEEYAAGDTIVEWGHAEDRFLVLAHGRAEQRAAGEYDDEAVVGVLADGE
                     YFDQWGLVDERIWDYSVRAVTTCTVLALRRSDFQALADRAPALRAHLDAFAADDAQGRD
                     GEVPINLAAGHTGEVELPGTYVDYQDAPREYDLSVAQTVLKVHTRVADLYNQPMDQVGE
                     QLRLTIEALRERQEHELINNSDFGLLHNADAKQRIHSRTGAPTPDDMDELLAKVWKDPE
                     FILAHPRAIAAFGRECSKRGIYPASVDMNGHQVPSWRGIPVLPCNKIPVSDTRTTSILL
                     MRTGEQNQGVVGLHQTGIPDEYEPSLSVRFMGIDEKAIISYLVSAYYSAAVLVPDALGV
                     LDNVQIGL"
     gene            8546..9940
                     /locus_tag="BLR56_RS01495"
                     /old_locus_tag="SAMN05421871_101301"
     CDS             8546..9940
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948855.1"
                     /locus_tag="BLR56_RS01495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101301"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_228769666.1"
                     /transl_table=11
                     /translation="MTGVLDPAATAQQSLSTNAARQLATTTKSVPQMQEITSRWLLRML
                     PWVNAAGAAYRVNRRLSYTVGDGRLTFTNVGATISVIPAELRELPLLRGLGDDATLDAL
                     AGRFVQREYAAGENIVTQGTPADAVHLIAHGKVTKSGTGHYGDRTVLAVMADGEHFGDD
                     ALLDSSAAWEFTVTTDTACTMLSLPRQEFLAMLERSEPLREHIDAVRASPTAAQNKYGE
                     AEIAMSSGHTGEPDLPGTFVDYDGAPREYELSVAQTVLRVHSRVADLYNDPMNQVEHQL
                     RLTIEALRERQEYELVNNRDFGLLHNADLRQRIHTRAGAPGPDDLDELLSRRRRSNFFL
                     AHPRAIAAFGRECTKLGLYPSTVEVQGRQLQAWRGVPLLPCDKIPISPTNTTSILVMRT
                     GESDQGVIGLHQTGIPDEYQPGLSVRFAGINEKAIISYLVSAYYSAAVLVPDALGVLEN
                     VQIGLG"
     gene            10001..11041
                     /locus_tag="BLR56_RS01500"
                     /old_locus_tag="SAMN05421871_101302"
     CDS             10001..11041
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034060.1"
                     /locus_tag="BLR56_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101302"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_091370250.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5e-63, bitscore:
                     208.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTEVITGFRSAREVLAQSRSLLDPALRAAVDTLPKSMRRIAGY
                     HFGWWDEHGWATTADAGKAVRPALVMTAAEAVGGSAATAVPAAVAVELVHNFTLLHDDV
                     MDGDRTRRHRPTAWSVFGLGPAILAGDALLTLAYDVLAASEHPRAQEGSRLMSAAVLAV
                     QEGQATDLAFEKRADVDLAECVHMAEGKTGALLGCSTALGALFGGGTPAQVDNLRIYGV
                     RLGLAFQLVDDLLGIWGDPAATGKPVYSDLENRKKSLPVVAALASGTQAARELAALYHR
                     RTPLSPTDLARAADLIDQSGARTWTQTHADDVLAEALDHVRSAGVTPRSTAELDAMAHL
                     IGRRDH"
     misc_feature    10070..10072
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12090..12533)
                     /locus_tag="BLR56_RS01505"
                     /old_locus_tag="SAMN05421871_101303"
     CDS             complement(12090..12533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685773.1"
                     /locus_tag="BLR56_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101303"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_091381983.1"
                     /transl_table=11
                     /translation="MRIQPTTLAPDLYRRLVELHMAVDKQAVEAGVERSLLELVRIRAS
                     QLNGCAFCVDMHTTAAVEAGETPRRLHALSVWAGTPFFSDRERAALALAESVTLLSERR
                     VSEEVYQRAEEEFDKDQLAHLIWAITVVNAFNRLAVTAELQPQ"
     gene            complement(12530..14110)
                     /locus_tag="BLR56_RS01510"
                     /old_locus_tag="SAMN05421871_101304"
     CDS             complement(12530..14110)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (32-429). E-value: 1.9e-59.
                     Score: 193.2. Matches aSDomain:
                     nrpspksdomains_BLR56_RS01510_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335620.1"
                     /locus_tag="BLR56_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101304"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_091381980.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-53, bitscore:
                     178.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTDLGTLFDDLVDRGVRTIVELSRPLDIAPNHGTQYTVAQLAA
                     LVRGAAGWLHAAGVRPGDRVAVVKENHWDYVLLACAAARIGAVPALLSDHVPPPALQLL
                     LKRLDPVLLVTTCAVLDRARDHETDLLGFARRTLTLDGPHPGALDLENLRGKEPPPPVL
                     RDIDEPLVVNHTSGTTGTPKLVIHSTRTLIHGLSATEATRLPVVSSRPTDTVCTSIAFC
                     HGRAIPWTASVLWLAPRKVVIIPDASDAEHTLRAHPPTTLEALPSTFVRWQPLARRPDN
                     PFRNVRLYVSTFDAVHPPTIRTFLDATARRPLWVQVWGQTETGPLTFRFLTRRSVAHRE
                     ARHPGTRNLGRPAPGRVRLRVVDPRTFRPVPPGRPGLVLARTAVRCLGYVGEQERWQDK
                     VSDGWWNTGDIGVRTRTGAYLLLDREVDVIPGQSCVELEDVIEDRLPAVTECVVLGTPG
                     QLPVPVLVTNGINQGEWNHAVRDLPALADPVVLAWDDVPRTGTGKVRRMELRTLIRRGN
                     DTFGTGRWT"
     aSDomain        complement(12824..14014)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BLR56_RS01510_AMP-binding.1"
                     /evalue="1.90E-59"
                     /label="BLR56_RS01510_AMP-binding.1"
                     /locus_tag="BLR56_RS01510"
                     /protein_end="429"
                     /protein_start="32"
                     /score="193.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="NHGTQYTVAQLAALVRGAAGWLHAAGVRPGDRVAVVKENHWDYVL
                     LACAAARIGAVPALLSDHVPPPALQLLLKRLDPVLLVTTCAVLDRARDHETDLLGFARR
                     TLTLDGPHPGALDLENLRGKEPPPPVLRDIDEPLVVNHTSGTTGTPKLVIHSTRTLIHG
                     LSATEATRLPVVSSRPTDTVCTSIAFCHGRAIPWTASVLWLAPRKVVIIPDASDAEHTL
                     RAHPPTTLEALPSTFVRWQPLARRPDNPFRNVRLYVSTFDAVHPPTIRTFLDATARRPL
                     WVQVWGQTETGPLTFRFLTRRSVAHREARHPGTRNLGRPAPGRVRLRVVDPRTFRPVPP
                     GRPGLVLARTAVRCLGYVGEQERWQDKVSDGWWNTGDIGVRTRTGAYLLLDREVDVI"
     CDS_motif       complement(13550..13597)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BLR56_RS01510_0001"
                     /evalue="3.50E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="BLR56_RS01510"
                     /protein_end="187"
                     /protein_start="171"
                     /score="13.6"
                     /tool="antismash"
                     /translation="VNHTSGTTGTPKLVIH"
     gene            complement(14107..14895)
                     /locus_tag="BLR56_RS01515"
                     /old_locus_tag="SAMN05421871_101305"
     CDS             complement(14107..14895)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685771.1"
                     /locus_tag="BLR56_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101305"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_228770184.1"
                     /transl_table=11
                     /translation="MADAAAPTRYVFGTAFDREEERLAHGEALWDKGTIEKLSHLGVDE
                     TWHCLEVGAGRGSVAAWLAARGAEVTAVDLDISRLGRLGALGVALWELDISRDPLPEGA
                     YDLIHARLVMQHVGDRAAAVRGMCRALRPGGYLVLEDTDTTSLFSHVDGEFHALVKRAA
                     YEVMIDAGYHPRCGLLDVELVEAAGLSSVHADGRAEVVRGGSDGARWFALWLEHLRPAM
                     VARGTVSDVDIDFAVSDLADPRHRWLSQVMVTVTGRKDDR"
     gene            complement(14888..16204)
                     /locus_tag="BLR56_RS01520"
                     /old_locus_tag="SAMN05421871_101306"
     CDS             complement(14888..16204)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003091357.1"
                     /locus_tag="BLR56_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101306"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_228770183.1"
                     /sec_met_domain="DAO (E-value: 4.2e-08, bitscore: 29.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADLDVAIVGAGVAGLSLAFRLRQAGRSVHVFESTAHVGGRMRS
                     VRREGYLIDTGAEMIGTHGYPATWRLMRDLGMSEEDTPLIGGDLAMWREGQAHPYVGDP
                     RGMVSGAGLTAAGRVSLAKLMASAAVRKRSFDVDRPEHTPLGVTTVREFARRYHPDVHD
                     YLLQPLCGGFFGWDTDRAAAGPLLSHLLAVGPTKSFRTWRDGMDTLARTLASRVEVSTG
                     VAVQEVTQTPEGARVTVDGAALTARQVVLCVPAPVAVDLHSGAPDFVRACEFQPMVKVV
                     CLLDRPIGVGGASWAVEVPAVENPAFAGFILDDRKHPDRVPPGRGMVTLFAGADASRLL
                     DLSNDQVVDTLVRQAGRYLPDLAAACRVSVVVRFRHGLPMPTAASLAARAAFVRRPVSS
                     IDYAGDWCVQRPSSEGAVRSAELVARRIMADNPLAVLRG"
     gene            complement(16201..17139)
                     /locus_tag="BLR56_RS01525"
                     /old_locus_tag="SAMN05421871_101307"
     CDS             complement(16201..17139)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685769.1"
                     /locus_tag="BLR56_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101307"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_091381976.1"
                     /transl_table=11
                     /translation="MTAITDVMPGRAGVYARLAKLDVWDYYLALPLAWSIIGPAAWFQP
                     SVLGMLALFGIGTVFVVASAVTFDDVTGFVDGSDNANYGPDAPARKLARKPLLTGEITV
                     VEAVRFGWCAAALGAVFWALAALVAPFSLMWTVGLATLCLVTAVQYSWGLKISYRGWQE
                     VFLAAFGIGLVLCAVGFATGTVSVFGIVQAVLFGFGPLMFGVYSNTRDAAGDAAVGRPT
                     VAALATENGNRLFIAGLTVAETALIVAAAGLGAAPWWFSLVMLPAIILRVAQLHRGIGL
                     GDLLGARTLGLRVHRLTTALLIAVNLVGAWS"
     gene            complement(17136..18260)
                     /locus_tag="BLR56_RS01530"
                     /old_locus_tag="SAMN05421871_101308"
     CDS             complement(17136..18260)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685768.1"
                     /locus_tag="BLR56_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101308"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_091381974.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-99,
                     bitscore: 330.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPFFPPDLFDDDRELLLDTVRRVGLAEEQKFILGERTARFEEA
                     LREQIGAADVVACGSGTTALMLVLRSMDIGPGDEVVVPAFGCAPLAASVVNVGATPVFA
                     DVHPWTMVVEPYEVEQAITGRTAAIMPAHMFSVMADMPTMRSLAERHDVRLIEDSAVAQ
                     GGVLDGIPAGRWGEAGVFSFVQVKTFGSIGEGGAVVTDDEEIGQRVRMLRNHGQDGKQR
                     FVHHFVGFNSRFDEIMAEFQLHRLAGLAARLERRAQIADYYTERFSGLVERGIQPPPTG
                     REGRCFYVYSLLADRRDELKRHLTEHGVGTHVYYPSPLPAQPAFAEYAPPGRFWPHAEL
                     ASSRILALPIYPHLTDAQVEHVADAVCAFPGGRP"
     gene            complement(18257..19468)
                     /locus_tag="BLR56_RS01535"
                     /old_locus_tag="SAMN05421871_101309"
     CDS             complement(18257..19468)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685767.1"
                     /locus_tag="BLR56_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101309"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_091381972.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8e-113,
                     bitscore: 373.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.3e-06, bitscore:
                     22.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHAATFADPAAAQAPGAGGTVPFFTQAASFADLWPLTEANLNAV
                     IDRGKYSHGHLVAEFESVLAERIGAAHVIGVNSGTDALVLLLRAAGLGPGDEVVVPAFS
                     FVASASSVALAHGRPAFADIDPVTYGIDPASAADAITDRTRMIMPVHLFSQLADMAAIT
                     EVAEQYALTVVEDSAEAIGMRWDGVHAGLLGIGGVLSFFPTKTLGALGDAGAVITNDDR
                     IAETAAALRHHGRYGRTIDHFPGISNETVLPGLNSKMDDFQAAILLAKLTRLDADIARR
                     AELAAAYTERLTGCPGVRRLPTVVEREVKTDAVFYVYLIEVERRDELVAHLAANGVTTE
                     TYYPVPLHRQPCFAELGHRAGEFPNAEAACAHAVALPLYPDLAERQVDRVCELIRAFYS
                     GSRP"
     misc_feature    complement(19485..19501)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            19696..20673
                     /locus_tag="BLR56_RS01540"
                     /old_locus_tag="SAMN05421871_101310"
     CDS             19696..20673
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013567.4"
                     /locus_tag="BLR56_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAMN05421871_101310"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_091381969.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-08, bitscore:
                     31.3, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGTLVVGLGRAGTELHLPVLRRLRPDAPVVVFDPHRTARTDGVT
                     VADSLPHAARLIDPANTVVHLCTPPSARVAPLTALAELGFRRVLVEKPLAADDRDLREV
                     LALREAARLDLLPVGQWRASELTRRLASILRERRLGRPRSITIVQSKPRFARTALGDEH
                     PSAFDVEVPHSVLLALLLAGPAEVLGAHCSDMLLGDEVYPALGGAVLRLSHASGVRTEI
                     RTDLTSPIRERKVTIDLDGGTVVGHFAVSAADDHAQLRVSTQGQQLRSVFRDDSLGAFL
                     AHAYRHFAGEDRITDEPDTGAAVVELISAAKRLSGVAVPEGASR"
ORIGIN
        1 tcgcggcggc ggggaggtca ccttgacgca gcgcgatctc gccgcgcacg ccgttgagca
       61 cggcctgcca ggtgaccgac ctgcgcttgg tcgcctccgt cagcagggac gcgcaccagg
      121 tggcggcgcg gtcgacgcgg tcggcgtgga tcagggcggc cagggccgac acctgggcgc
      181 cgaaggcctg ctcgccgagc cggcagctgc gcaggatgtg ctccgcgtcg gtcgcggtgc
      241 gcgcgtcgga ctcccccgcc ctgatccggt cgagcagggc gcccgcgcgg ctccacgggt
      301 cgttgcggcc ggacggcttg gggagcacct tgatccgggc gctcgccacc gggttgacga
      361 acgacagcca gccgacgacg aggccgatgt ggccggactt gggcttctca cccgccgcca
      421 ccgacgcggc caggcccgcg agtgtgcccg ccagatcctc ggtgtggccg gaccagaaca
      481 ggtgcttggc caaatgcacg gcgttgtggt cggccagggt gccccgggcc cgggcgtcga
      541 gcagcggggt gaggtggcgc agcgcggcgg tcgggttgga ccgccactcg acgcgcagca
      601 gctgggtgac gatgtcggca tgctcggtct cgtcggcgca gcagcgggcg gcgaggtcga
      661 gccgggcgac ggccaggtcg agccggtcgg cggcgagggc ctcgcgggcc gcgtgccgca
      721 ggacgctgac ggcccaggtc ccgtcgggtt ggtcggcggc gacgaggtgg tcggccacct
      781 gggtctccga agcgccctcg cggtgcagca gtcgggccac ccgcaggtgc cgagcggcgc
      841 ggtcggcggg ggccagccca cgcaagaccg cggcgcgggc caccgggtgg cggaaccggc
      901 cgccgtcgag cagcccggcg gtctcgagca cctcgagtac ctgggcggcg gcgtccgcgc
      961 ccatgtccag cagcttgccg accatggcgg gcgtgcccgc gtcgccgagc agcgccagcc
     1021 cgcgcgcgac ttcgagcatc gccggttccc agcggtgcag gcaggcgatg acggcctggt
     1081 cgtaggcctg gccgacggcc atctccttct cccggcccgc cccggaccgc acctcggcgc
     1141 ggtagtcctc gatcagggcg tgcgcgagca gcgggttgcc gccgctcagc gcgtggtgca
     1201 cgggggccag cgcccgggcg gtgaccgggt cgagctcggc gcggatcagt tcctcgacac
     1261 cgcgcttcga cagcgccgcg agccgcaggt gcgtggtgtt gggctggcgg gtcacctcgg
     1321 cgcggaacac cgcgcgggcg ggccggggca gcgcccactc ggtcaggacg atcatgactc
     1381 gggcgaagcg catccggcgc agcacataaa gcagggcctg cagggacggc gcgtcggcga
     1441 actggacgtc gtcgacggcg acgacgacgg gctgccgcct gcccgcctcc gtcaacgccg
     1501 cgcaaaggcc ctccaggacc accgcgcgtg accggccgac cgacacctgg tcgggccgca
     1561 ccgcggaagg atcagccatg gccgccgcga ggtcgtcgcc cgcgagcagg caggcgatcg
     1621 tctcggccac ggcctcgggt aaagcggggc cgctgaacaa ctgcttcagg acgccgaacg
     1681 gcaggctgtg ctcggctcgg gaagcggtgg cggtcagcac ggtcgcgccc ttgcccctgg
     1741 cgtgttcggc gaaggtgtgc agaagttcgg tcttgccgct ggcgactccg ccgctgacca
     1801 gcgcgacctg cccccgatcg cgtgcgcact cggcgaacag ccgattcagc gttttcagtt
     1861 cctcattgcg ttcgaccagc gccatcccgt cgccctcccc tgcgagggac gcggccgggc
     1921 agcccgcgca agagcccagt cgcgtcactc atcgtgacca tattttgccg ttgccccacg
     1981 gtcgaccctg aatctaacgg catttccgcg cattgtggaa ggttcgccaa gtgaaggctg
     2041 gaacaatgcg aggtccagcg cccgcgccag ggccagggtg acccattcgg cccatcacac
     2101 tggccccgaa gcgggacaac accagtcagg tttgcgggtc cgcaagggct ttcgccgaca
     2161 gatcgacacc cgatgacgcg accagggacc ggttactcca catgggaacg accgttggcc
     2221 agtttccaac agcaaacctc aagaagagat caagtccggt gtggacaggg ttgctgcatc
     2281 cggctcaatg ggacaccgag tggcctatcg cgcaccatgg ttgcgccttt tagtggccgg
     2341 actttgctca ctgtgtgtaa gtggtgccgg atcgcgattc gtcactttgg ggggcacacc
     2401 cgagggccca cgaaggtcac gcgactgact acgttgacga ctaacggtgt ggaagggttc
     2461 gtgatgcggc attcggagcg ggagcagctg atcaacgcgc tggccacgcc tgcacggcac
     2521 gccgacgcgg ccgcgatgct ccgctcgctg cccaaactcg gctggctgtc cgcgcggcgg
     2581 gccaaacggc tgcgccaagc cgtcctcgac gcactggccc gcgacgtccc ggcttggtcg
     2641 atcgtggcga tgctcggcgg ccacgacacg gaggtggtcg tggccgcgat ggcgccgctg
     2701 gtcaccgacg gccccgatcc gggcatggcc gcgcatctgc tgctcacggc gctgcgaacg
     2761 cgaccatccg acagcgtctc cacccagccc cggcccgatg gcggccactg gggccaggtc
     2821 gatccgccgg tccggaagcg tccccggatt ccgccgcggg agcacatccc gccattcgtg
     2881 accgagcggc cgaaccgaga cctcacatcg ggcgacccgc catccggcgg gtggggaacg
     2941 ggcgcgtggc ggccaccgtg gctcgagcaa ccgtctaagc acgaccccac gcgcccggtc
     3001 acgcccgcca atccccccga cgacgtcgag cccttcgagg acttctcccc aggcccgccg
     3061 agcgcacgcg aggtgtggcc gactctggag tgtccggcgt cggtcgatat cgacgcgcag
     3121 ttcgatctca ccgtcggcat cggcccgaaa caggacatgg ccctgctcgg caccggcccg
     3181 atcacgctgc cgaacaacat ggtgcggctg gagatcgtgc tgatgtacga cccgaccgcg
     3241 ttcgccccgg tcgggtggtc gaacccggtc gtcctgaccg tcgacgccga gaacccgtat
     3301 ccggtggcga ccctgcggat gaccgcgctg cgcggggaga gcctgcgctc ccgccgcgac
     3361 atcggcgcgt cgttctacgt cgacggcggg ctgcgcggat acgcctcccg cgccatcgag
     3421 gtcacgggca cgccgtcggg caccgtgccg ctcttcggcg gcgcgatgct cgacatcgga
     3481 cccctgctca agcacgaggc gccggacctg gtcgtcgtgg tggagcgcgg cgaggacctg
     3541 cgcggccaga ccctgctgtg gagcaccaga agctcggttc ccggcgtcgc ctccgcgccg
     3601 ggtccgtacc gcagcgagat cggcgaggac ccggcggcct tcgcccgccg cgtgcggctc
     3661 gacgtcggcg cgttcggcgg cgacgcgcgc ggcagcaccc tcaagctgat cggcgtcggc
     3721 cggaccatcg ccgaccacat ccccgacgag gtctgcgccg cgctgaccgc ggtgagcacg
     3781 gcccgcgccc cggctcccgc caccgtgctg ctgctcagct ccgagccgca cgtgccctgg
     3841 gaactggcgg ttctcgaccc gccgcccgct gagggcagcc cgttcctcgg cgcgcgcatg
     3901 gcgatcgggc gctgggtgct ggcccggaaa cggccgcggc cgaccccgcc gaccgaggtc
     3961 cgcgccgacc ggcacatcgt ggtcaccgcc cggtacgaag gcgtgcccgg gtgggcgcgg
     4021 ctgccgttcg ccgaagccga ggccgagcgg ctgcgtctca cctacccgcc cgccgtggag
     4081 gtccagccgc tgcactcggc ggtgctcgac tgcctggagg cggggccgga cggcggtgtc
     4141 ctgcatttcg cgctgcacgg caagtacgac cccgagaacg cccaggacgg cctggtcctg
     4201 ctggcgccgt cggaggccaa cccggaccgg ctggtccccc ggttcctgca gccggaccag
     4261 gtgtccgcga tggcgttcag ctccgcgccc ttcgtcttcc tcaacgcctg ccaggtcggc
     4321 gccgcgggcg aggtgctcgg cgactattcg gggctggcga aggctttcct cgcggccggc
     4381 gcggcgggcg tcgtcgctcc actgtggaat gtcaacgacg aggcggccag cgcgctcgcc
     4441 gacgccttct accaggacgc ctatgggccg caggcgttgg cgcccgcgga gatcctgcgc
     4501 cgggcccgcg ccgaggtctc ccgtgaccac tacccgacct ggcccgcgac cacgctggcc
     4561 taccagttct tcggacaccc gcggctgcgg ctgcggcgcg atcaaggggc atgaccatgg
     4621 ctgaaccgct gcggccggac ggaaccgagg tgcgggtggg cgacgtcgtc gtcgtctcgc
     4681 cagggctcac ggggcaggtc gaggtgctgc tgccgggcac cgacggcatg cgcggcgcgg
     4741 aggacgcgcg gctggcgctg ctgcgcgcgt tggcgcgctg cgacttcacc gagcagctct
     4801 cggtgcgggt gatcgacccg gtggaggtcc cggaactcgc ctccggcgcg agccggtcga
     4861 ccagcctcgg cgagcccgcg atcagcgtcg aggtccccgg gcccgggtcc ggcctcgggc
     4921 aggtcgtgct cgccgcggac gaggaaggcg cgctgagctg gcacctgccc gacgacgtgc
     4981 cgcccgacga ggtgcccagc cgcggcggcg accggcgcac gtacaccttc cgccgggccg
     5041 tcgcaccgcc cgcggagccc ggtggctccc gcgggctgat cggggcggtc gggtcgaagt
     5101 tgttgaaggt cctggtgttc ccgctcatcg acccggtgct gggcaaggtc ggcgatcact
     5161 tcgccgggcg gtgggagcag aagaaccgga atgtgcggct gcgtgacttc gtcgaccacc
     5221 gggtcgcgga agcgggtccg gtcgactggc aggccctcgg cgccggtccc gcgctgctgt
     5281 tcgtgcacgg gaccgccagc cagagccaca ccggattcca cggcgtggca ccggagacgc
     5341 tgggcacgat ctcggcccgg tacggcgggc gggtgttcgc cttcgaccac cacacgctct
     5401 cggtcgaccc ggtggcgaac gcgcgctggc tggtcgagca gataccggcg ggggccgggc
     5461 tgaccgtcga catcgtggcg cactcccgcg gtgggctggt cgcgcgtgcg ctgtgcgaat
     5521 tggccgacga ggtcggcctg accgcggacc ggatgaccgt gcgcacgctg gtcatggtcg
     5581 ccacgcccaa cgcgggcacg ccgctgtgct cgccgacgaa catcactgcc tggctcgacc
     5641 ggatgaccaa cctgctgcaa tgggtgccgg acaacggtct caccgacgct ctggacattg
     5701 tcctgacggt cgccaagcag gtcgctgtcg gcgcgttgcg tggtctggac gggctgatgg
     5761 cgatggaccc gaaggggcag ttcctggtgg aacgcctcaa caagcccgct gagcacacgg
     5821 tgacctaccg ggcggtggcg tcgaactacg acccggtcaa gggctccggg ctgctgcgca
     5881 gcgcgcgcaa cgcctcgacc gacgtggtgt tcgggctggt gcccaacgac ctggtggtgc
     5941 ccaccgaggg cgtgttcgcg gccaacggcg cgagcgcgtt cccaatcgcg gagccacagg
     6001 tgttcgaggc ggccgacggc atcgaccaca gcggcttctg gccggacgca cgactcgtcg
     6061 ccgcactcga ccgctggctg gtgggctaac gcggcatctt gcgccacagt gcgcgcggca
     6121 gcactcgcat gatcccgaag atcggccgta ggacggcggg aacccacacc tcaccgcgct
     6181 tgccgccgag cgcgcgcacg gtggcggcgg cgacctggtc gggagtgctg gagaacggcg
     6241 cgggcgacat gccgtcggtc atccggccca cgacgaaacc ggggcggacc agcagcagcc
     6301 gcacgccact gccatgcagc gcgtcggcca gcccggaggc gaatccgtcc aggcccgctt
     6361 tcgcggagcc gtagacataa ttggcccgcc ggacccgcac acccgccacc gacgagaaca
     6421 ccacgacaat gccattcccc tgttgtcgca aaaggtttgc gatatgggtc agcacgctga
     6481 cgtgcgccac atagtcggta tgcaccacgc ggaccgcgtg cgcggaatcc cgctcggcga
     6541 ctttctggtc gccgaggatg ccgaaagcca ccacgatcgt gtcgatcggg ccgtgcgcgc
     6601 gggtgatctc cgcgagcagc ggttcgtgcg aggcgagatc gtcagcgtcg aactccaccc
     6661 gctcgactgt cgtcgcgccg gccgcacgca gggtcgactc ctcgacgtcg agatcgtcgc
     6721 tgcggcgggc ggccagcacg accgtgcgcg tgccgcgctc gaccagccgc cgggcgacgg
     6781 cgacgcctat ctcactgcgg ccacccaaga tcaccaacgg tcccattccg ccagtctgcc
     6841 tgggtgcccg cgggcgcgac acgccgggcg gaccggacgc gccgacatga tcgagtgaaa
     6901 gatcgacttt cgactactcc aagtcgatga tgaataccgc atcgagtgga cttcatcggg
     6961 ttatcaccat cccattcggg gactgtcggg tgactacgcc ccggtgctaa cttcgaaaac
     7021 gtcggcagcc caacaattcg gaccgacgtc cccccgcaca cctcattcca tttcccatgc
     7081 cctgaacaag gattggcggt accagtcgtg accgagacag tgcatcccct caaccctgcc
     7141 cggccggagg ccgcacagca gagcttgagc actgcggcgg cgcgcaacct cgcgaccaca
     7201 acgaaatccg cgccgcagat gcaggagatc acctcgcggt ggctgctgcg caaactgccg
     7261 tgggtgcagg tcaccggtgg tacgtaccgc gtcaaccagc ggcgcagcta caccgtgggc
     7321 gacggccgca tcgccgtcga ccggtccggc gccacggccc gcgtcgtcgc gggcgacctt
     7381 cgcgagctgg cctgcctgcg cgacttcgag gacgaggacg tgctcggcgc gctcgcgggc
     7441 ctgttcacgc aggaggagta cgccgcgggc gacaccatcg tggagtgggg ccacgccgag
     7501 gaccgcttcc tcgtcctcgc gcacgggcgg gccgagcagc gggccgcggg cgagtacgac
     7561 gacgaggccg tggtgggcgt cctcgccgac ggcgagtact tcgaccagtg gggcctggtc
     7621 gacgagcgaa tctgggacta cagcgtccgt gcggtcacca cgtgcaccgt gctggccctg
     7681 cgccggtcgg acttccaggc gctggccgac cgcgcacccg ccctgcgggc gcacctcgac
     7741 gcgttcgcgg ccgacgacgc gcagggccgc gacggcgagg tgccgatcaa cctcgcggcg
     7801 ggccacaccg gcgaggtcga actgcccggc acctacgtcg actaccagga cgccccgcgc
     7861 gaatacgacc tcagcgtcgc ccagaccgtg ctcaaggtcc acacccgcgt cgccgatctc
     7921 tacaaccagc cgatggacca ggtcggcgaa cagctccgcc tgaccatcga ggcgctgcgc
     7981 gagcgtcagg aacacgagct gatcaacaac tccgacttcg gcctgctgca caacgccgac
     8041 gccaagcagc gcatccactc ccgcaccggg gcgccgactc ccgacgacat ggacgagctg
     8101 ctcgccaagg tgtggaagga cccggagttc atcctcgccc acccgcgcgc gatcgccgcg
     8161 ttcggccgcg agtgcagcaa gcgcgggatc tacccggcca gtgtcgacat gaacggccac
     8221 caggtgccgt cctggcgcgg catccccgtg ttgccctgca acaagatccc ggtcagcgac
     8281 acccgcacca cgtcgatcct gttgatgcgc acgggcgagc agaaccaggg cgtcgtcggc
     8341 ctgcaccaga ccggcatccc cgacgagtac gagccgagcc tgtcggtccg cttcatgggc
     8401 atcgacgaga aggcgatcat ctcctacctc gtcagcgcct actactccgc cgccgtcctc
     8461 gtccccgacg cgctcggcgt actcgacaac gtccaaatcg gcctctgacg actctcgacc
     8521 cgaaccacga ttggcggatc accacgtgac cggcgtactc gaccctgcgg ctacagcaca
     8581 gcagagcctg agcaccaacg cggccaggca actggccacg accaccaagt ccgtcccgca
     8641 gatgcaggag atcacctcgc ggtggctgct gcgaatgctc ccgtgggtga acgccgcggg
     8701 cgccgcctac cgggtcaacc ggcgcctgag ctacaccgtg ggcgacgggc ggctcacctt
     8761 caccaacgtc ggcgccacga tcagcgtcat ccccgccgaa ctgcgcgaac tgccgctgct
     8821 gcgcggcctc ggcgacgacg ccaccctcga cgccctcgcg ggccggttcg tccagcggga
     8881 gtacgccgcg ggcgagaaca tcgtcaccca gggcaccccg gccgacgcgg tccacctgat
     8941 cgcgcacggc aaggtcacca agagcggcac cggccactac ggcgaccgga ccgtgctggc
     9001 cgtgatggcc gacggcgagc acttcggcga cgacgccctg ctcgattcga gcgcggcgtg
     9061 ggagttcacc gtcacgacgg acaccgcgtg cacgatgctt tccctgcccc gccaggagtt
     9121 cctggcgatg ctcgaacgct ccgagccgct gcgcgaacac atcgacgcgg tccgcgccag
     9181 cccgacggcc gcgcagaaca agtacggcga agccgagatc gcgatgtcct cgggccacac
     9241 cggtgagccg gaccttcccg gcacgttcgt cgactacgac ggcgcgccgc gcgagtacga
     9301 actcagcgtc gcccagaccg tcctgcgcgt gcactcgcgc gtcgcggatc tctacaacga
     9361 cccgatgaac caggtcgagc accagctccg gctgaccatc gaggcgctgc gcgaacgcca
     9421 ggaatacgag ctcgtcaaca accgcgactt cggcctgctg cacaacgccg acctgcgtca
     9481 gcgcatccac acccgcgcgg gcgccccggg tcccgacgac ctcgacgagc tgctgtcgcg
     9541 caggcggcgg tccaacttct tcctcgccca cccgcgcgcg atcgccgcgt tcgggcggga
     9601 atgcaccaag ctcgggctct acccgtccac agtggaggtc cagggcaggc agctgcaggc
     9661 ctggcgcggc gtcccgctgc tgccgtgcga caagatcccg atcagcccca ccaacacgac
     9721 gtcgatcctg gtcatgcgca ccggcgagtc cgaccagggc gtcatcggcc tgcaccagac
     9781 cggcatcccc gatgaatacc agcccggcct gtcggtccgg ttcgcgggca tcaacgagaa
     9841 ggcgatcatc tcctacctcg tcagcgccta ctactccgcc gccgtcctcg tccccgacgc
     9901 gctcggcgta ctcgagaacg tccagatcgg cctgggctga ccgggcacga cccaacatag
     9961 cgtccacagt ggaccattaa cgaggagatc cgccaccaca atgtccacca ccgaggtgat
    10021 caccggcttc cgctccgcac gcgaggtgct cgcccaaagc cgaagcctgt tagaccccgc
    10081 tctgcgcgcc gccgtggaca cgctccccaa gtccatgcgg cggatcgccg gctatcactt
    10141 cgggtggtgg gacgagcacg gctgggcgac gaccgcggac gcgggcaaag cggtccgccc
    10201 ggcactggtg atgaccgcgg cggaggcggt cggcgggtcg gcggccacgg ccgtccccgc
    10261 cgccgtcgcg gtcgaactgg tgcacaactt caccctgctg cacgacgacg tcatggacgg
    10321 cgaccggacc cgccgccacc gccccaccgc gtggagcgtc ttcggcttgg gcccggccat
    10381 cctggcgggc gacgccctgc tgacgttggc ctacgacgtc ttggcggcca gtgagcaccc
    10441 ccgggcccag gagggttccc gcctgatgtc ggcggccgtc ctcgccgtcc aggagggcca
    10501 ggccaccgac ctggccttcg agaagcgcgc cgacgtcgac ctggcggagt gcgtccacat
    10561 ggccgaaggc aagaccggcg ccctcctcgg ctgctccacg gcgttgggcg ccttgttcgg
    10621 cggcggcacc cccgcccagg tcgacaacct ccgcatctac ggcgtacgcc tgggcctggc
    10681 tttccagttg gtggacgacc tgctaggtat ctggggtgac ccagcggcca ccggaaagcc
    10741 ggtctactcg gacctcgaga accgcaagaa gtccctcccc gtggtcgccg ccctggcctc
    10801 aggcacccag gccgcccgcg aactggcagc cctctaccac cgccgaaccc ccttgtcccc
    10861 caccgacttg gcacgcgccg cggacctcat cgaccagtca ggcgcccgaa cctggaccca
    10921 aacccacgcc gacgacgtcc tcgccgaagc cttggaccac gtccgcagcg caggtgtcac
    10981 cccccgctcc accgccgaac tagatgcgat ggcccacctc atcggtcgcc gagaccactg
    11041 aaccgtggag aggttggagc ggttggagcg ggaagatccg gcaagagcgc accggcgaga
    11101 acttgactga ctttgggacg gcaaacgttg gcacccaaag gtgatcgagg tcgaccgacg
    11161 gtgggaccag ccaattccgg cgcagaacca actgccccac ccacagcatc actcgcaggt
    11221 cacccacagc cccacccgca agtcacccgc aaccccaccc gcagatcacc cacatcccca
    11281 cccgcaagtc acccacagcc ccacccgcaa gtcacccaca accccacccg caagtcaccc
    11341 acagccccac tcactgcacc accgacagcc cccaccccgg acggggttgc ctatgcggtc
    11401 tttggctttt aatccctgct ctatcccctg ccccctcgtc ctggccatct ttaactctcg
    11461 atcatcggtg tcaagggtcg cgcagcgatc gcgcagcgac ggccgtttac ggccgccctt
    11521 gacgccgatg atcgagagtt aaacaattgt ggccgaggga gactgatttc ccttgggagc
    11581 caacaagaac tcggggatca acgcggtggg cccctctggc tcgattgttt aattctcgat
    11641 catcggcgtc aagggcggcg caagcgccgt cgctgcgcga tcggcaagcc gacccttgac
    11701 agcgatgatc gagaattaaa agcggccagg acgaggggca agggggaagt gcaggggcga
    11761 agagccgtcc ccgacggtga ccacgtccgg aggtcaaggg cgagggcggc ccctggggca
    11821 gggcaaagag ctgtccccga gggataatcg ttcgggacta cacggcaagg gctgtccctg
    11881 acggcctact cggtcggggg tgcagcgcaa tgagccgtcc ctgatcggct acgcaccaag
    11941 ggtgcaggcc cggttcgctc gctcgaggct gggccgagga atgcggtcgt atgggtgccg
    12001 ggagtcgttc gggtgactgg ggtggccggg tcttagggaa tgttgcggaa cacaagtgat
    12061 gcagcagggc ggtgaccttc gccgttgtgt tactgcggtt gcagttccgc agtcaccgcg
    12121 agccggttga aagcgttcac caccgtgatc gcccagatca ggtgtgccag ctggtccttg
    12181 tcgaactcct cctcagcccg ctggtacacc tcctccgaca cccgcctctc cgacagcagt
    12241 gtcaccgact ccgccaaggc cagtgcggct cgttcccggt cggagaagaa gggcgttccg
    12301 gcccagacgc tcaacgcgtg cagccgtcga ggggtttccc cggcctccac tgcggccgtg
    12361 gtgtgcatgt ccacacagaa ggcgcagccg ttcagttggg aggcgcggat tctgaccagt
    12421 tccagcagtg accgctccac cccggcctcg accgcctgct tgtcgaccgc catatgcagc
    12481 tccaccagcc tgcggtacag gtccggggcg agtgtcgtcg gttggattct catgtccagc
    12541 ggcccgttcc gaaggtgtcg ttgcctcgtc tgatcagcgt gcgcagttcc atccggcgaa
    12601 cctttcccgt gccggtgcga ggaacgtcgt cccacgccag gaccacgggg tcggccaggg
    12661 ccgggaggtc ccgtaccgcg tggttccact cgccctggtt gattccgttg gtgaccaaca
    12721 ccggcaccgg cagctgcccg ggcgtgccga ggaccacgca ttcggtcaca gcgggcaggc
    12781 ggtcctcgat gacgtcttcc aattccacgc agctctggcc ggggatgacg tcgacttccc
    12841 tgtccagcaa caggtacgcc ccggtccggg tgcgcacacc gatgtcgccg gtgttccacc
    12901 aaccgtcgct taccttgtcc tgccagcgtt cctgttcgcc cacataccca aggcaccgca
    12961 ccgccgtgcg tgccaggacc aagccggggc ggccgggggg caccggtcgg aacgtccgcg
    13021 gatcgaccac gcgcaaacgg acgcggcccg gcgcgggcct gccgaggttg cgggtgccgg
    13081 ggtggcgggc ttcgcggtgg gcgactgatc gtcgggtgag gaagcggaag gtgagcgggc
    13141 ctgtctccgt ctgaccccag acctgcaccc acagcggcct gcgggcggtc gcgtcgagga
    13201 aggtgcggat cgtgggcggg tgcaccgcgt cgaaggtgct gacgtagaga cgcacgttcc
    13261 tgaacgggtt gtccgggcgt cgggcgaggg gctgccagcg gacgaaggtc gacggcagcg
    13321 cttcaagggt ggtcggtggg tgcgcgcgca aggtgtgttc ggcgtcggaa gcgtcgggga
    13381 tgatgacgac tttgcgcggg gccaaccaca acacgctcgc ggtccagggg atggcccggc
    13441 cgtggcagaa ggcgatcgac gtgcacaccg tgtcagtcgg gcggctcgac accaccggca
    13501 gtcgggtcgc ctcggtggcg gacaggccgt ggatgagggt gcgcgtgctg tggatgacca
    13561 gcttcggcgt gccggtcgtg ccggacgtgt ggttgaccac cagcggttcg tcgatgtccc
    13621 gcagcaccgg cggcgggggc tccttgccgc gcaggttctc caggtccagg gcgccggggt
    13681 gcggtccgtc gagggtgagg gtgcgccggg cgaagcccag caggtcggtc tcgtggtcgc
    13741 gggcgcggtc gagcacggcg cacgtcgtga ccagcagcac cgggtcgagc cgcttcagca
    13801 gcaactgcaa cgccggcggc ggcacgtggt cggacagcag ggcgggcacc gcgccgatcc
    13861 gcgcggcggc gcaggcgagc agtacgtagt cccagtggtt ctccttgacc accgccaccc
    13921 ggtcgcccgg acgcaccccc gccgcgtgca gccagcccgc cgcgccccgc accaaagcgg
    13981 ccagttgcgc gacggtgtac tgggttccgt ggttgggcgc gatgtccagc ggcctgctca
    14041 gctcgacgat cgtgcggacg ccgcggtcga ccaggtcgtc gaacagggtg ccgaggtccg
    14101 tgggcttcat cggtcgtcct tcctgccggt gaccgtgacc atgacctggg acagccagcg
    14161 atgcctcggg tcggcgaggt cggacaccgc gaagtcgatg tccacatcgg acaccgtgcc
    14221 gcgcgcgacc atcgcgggcc gcaaatgctc cagccacaac gcgaaccacc gggcgccgtc
    14281 gctgccgccg cgcaccacct ccgcgcgccc gtctgcgtgc acgctcgaca gtcccgccgc
    14341 ctccacgagt tcgacgtcga gcagcccgca ccgagggtgg taaccggcgt cgatcatgac
    14401 ctcgtacgcc gcacgcttca ccagtgcgtg gaactcgccg tcgacgtgac tgaacagcga
    14461 cgtcgtgtcc gtgtcctcca ggaccaggta gccgccgggc cgcaacgccc ggcacatccc
    14521 gcgcacggcc gccgcgcggt cgccgacgtg ctgcatgacc agccgcgcgt ggatgaggtc
    14581 gtaggcgccc tcgggcagcg ggtcgcggct gatgtcgagt tcccaaaggg cgacgcccag
    14641 cgcaccgagc ctgcccagcc gggagatgtc gaggtcgacc gcggtgacct cggccccgcg
    14701 cgcggccagc caggccgcga cggacccgcg gcccgcgccg acctccaggc agtgccaggt
    14761 ctcgtcgacg cccaggtggc tgagcttctc gatcgttccc ttgtcccaca acgcctcgcc
    14821 gtgggcgagc cgctcctcct cacggtcgaa cgccgtgccg aagacgtacc gggtgggagc
    14881 cgccgcgtca gccacggagc accgccaacg ggttgtcggc catgatccgg cgcgccacca
    14941 gttcggcgga ccgcaccgca ccctcactgc tgggccgctg aacacaccag tcgcccgcgt
    15001 agtcgatgga cgacaccggc ctgcggacga aggccgcgcg cgcggccagc gaggcggcgg
    15061 tcggcatcgg cagcccgtgc cggaagcgca cgacgaccga cacccggcac gcggcggcga
    15121 ggtcgggcag gtagcgcccc gcctgccgga ccagcgtgtc gacgacctgg tcgttggaca
    15181 ggtcgagcag cctgctcgcg tccgccccgg cgaagagcgt caccatgccg cgcccgggcg
    15241 gcacgcggtc cgggtgcttg cggtcgtcga ggatgaaccc cgcgaacgcc gggttctcga
    15301 ccgcgggcac ctccaccgcc cacgacgcgc cgcccacgcc gatgggccgg tcgagcaggc
    15361 acaccacctt gaccatcggc tggaactcgc acgcgcgcac gaagtccggc gcccccgagt
    15421 gcaggtcgac cgcgaccggc gcgggcacac acagcacgac ctgccgcgcg gtcagggccg
    15481 ctccgtcgac ggtgacccgt gccccttcgg gtgtctgcgt gacctcctga accgcgacac
    15541 ccgtgctcac ctcgacccgc gaggcgagcg tccgggcgag ggtgtccatg ccgtcgcgcc
    15601 acgtgcggaa cgacttggtc gggccgacgg cgagcaggtg gctcagcagc ggcccggcgg
    15661 cggcgcgatc ggtgtcccag ccgaagaatc cgccgcacag cggctgcaac aggtagtcgt
    15721 ggacatcggg atggtaccgc cgcgcgaact cccgaaccgt cgtcacgccc agcggtgtgt
    15781 gctccggccg gtcgacgtcg aaagagcgct tgcgcaccgc cgccgacgcc atcagcttgg
    15841 ccagactcac ccggcccgcc gcggtcagcc cggcgccact gaccatgccg cgcgggtcgc
    15901 cgacataagg atgcgcctga ccttcccgcc acatcgcgag gtcgccgccg atcagcggtg
    15961 tgtcctcttc ggacatcccg aggtcgcgca tcagccgcca ggtggccggg tagccgtggg
    16021 tgccgatcat ctcggcgccg gtgtcgatga ggtagccctc gcggcgcacg ctgcgcatcc
    16081 ggccgccgac atgcgcggtg gactcgaaca cgtgcaccga ccggccagct tgccgcagcc
    16141 ggaacgccag ggacagcccg gcgacgccgg cgccgacgat ggcgacgtcg aggtcggcgg
    16201 tcacgaccag gctccgacca ggttgaccgc gatgagcaga gccgtcgtca gccggtgcac
    16261 gcgcaggccg agcgtgcgcg ccccgagcag gtcgcccaac ccgatgccgc ggtgcagctg
    16321 ggccacccgc aggatgatcg cgggcagcat caccagggag aaccaccatg gggccgcgcc
    16381 gagcccggcc gcggccacga tcagcgcggt ctcggcgacc gtgaggcccg cgatgaacag
    16441 ccggttcccg ttctccgtgg ccaaagcggc cactgtgggc cgacccaccg ccgcgtcacc
    16501 ggccgcgtcg cgggtgttgg agtagacacc gaacatgagc ggcccgaatc cgaagaggac
    16561 cgcctgcacg atgccgaaga cgctgaccgt cccggtggcg aacccgaccg cgcagagcac
    16621 caggccgatg ccgaacgcgg cgaggaacac ctcctgccag ccgcggtagc tgatcttcag
    16681 cccccacgag tactgcaccg cggtcaccag gcacagcgtg gccagtccga ccgtccacat
    16741 tagactgaat ggtgcgacaa gcgccgccaa cgcccagaac accgcgccca aagccgccgc
    16801 gcaccacccg aagcgcaccg cttcgaccac ggtgatctcg ccggtcagca gcggcttgcg
    16861 cgcgagcttg cgagcgggcg cgtccggccc gtagttggcg ttgtcgctgc cgtcgacgaa
    16921 cccggtcacg tcgtcgaacg tgaccgccga ggccaccacg aacaccgtgc cgatgccgaa
    16981 cagcgcgagc atcccgagca cgctcggctg aaaccacgcc gcgggcccga tgatcgacca
    17041 ggcgagcggc agagcgaggt agtagtccca gacgtcgagc ttggccagcc gggcgtagac
    17101 cccggcccga cccggcatga cgtcggtgat cgccgtcatg gtcgtcctcc cgggaaggcg
    17161 cagaccgcgt cggcgacgtg ttccacctgg gcgtcggtca ggtgcgggta gatgggcagc
    17221 gccaggatcc gggagctggc cagctcggcg tgcggccaga accgcccggg cggcgcgtac
    17281 tcggcgaacg cgggctgcgc gggcagcggc gacgggtagt agacgtgcgt gccgacgccg
    17341 tgctcggtga ggtggcgctt gagttcgtcg cggcggtcgg cgagcagcga gtagacgtag
    17401 aagcagcggc cctcgcggcc ggtgggcggc ggctggatcc cgcgctcgac cagtccgctg
    17461 aaccgctcgg tgtagtagtc ggcgatctgc gcgcggcgtt cgagcctggc cgccagaccg
    17521 gccagccggt gcagctggaa ctcggccatg atctcgtcga accggctgtt gaagccgacg
    17581 aagtggtgca cgaaccgctg tttgccgtcc tggccgtggt tgcgcagcat ccgcacccgc
    17641 tgcccgatct cctcgtcgtc ggtgacgacc gcgccgccct cgccgatcga gccgaaggtc
    17701 ttgacctgca cgaacgagaa cacgcccgcc tcgccccagc ggcctgcggg gattccgtcc
    17761 aggacaccgc cctgggcgac cgccgagtcc tcgatcagcc gcacgtcgtg tcgctcggcc
    17821 agcgagcgca tggtcggcat gtcggccatc accgagaaca tgtgcgcggg catgatcgcc
    17881 gcggtccggc cggtgatcgc ctgctcgacc tcgtagggct cgaccaccat cgtccacggg
    17941 tgcacgtcgg cgaacaccgg tgtcgcgccg acgttgacca ccgacgcggc cagcggcgcg
    18001 cagccgaacg cgggcacgac gacctcgtcg cccggcccga tgtccatcga gcgcagcacc
    18061 agcatcagcg cggtcgtgcc gctgccgcag gccaccacgt cggccgcgcc gatctgctcg
    18121 cgcagcgcct cctcgaaccg ggcggtgcgc tcgccgagga tgaacttctg ctcctcagcc
    18181 agcccgaccc ggcgcacggt gtcgagcagc agctcgcggt cgtcgtcgaa caggtcgggc
    18241 gggaagaagg gaagggtcac ggcctgctcc cgctgtagaa ggcccggatc agctcgcaca
    18301 cccggtcgac ctggcgctcg gccaggtccg ggtagagcgg cagcgcgacg gcgtgggcgc
    18361 aggcggcttc ggcgttgggg aactcgcccg cccggtggcc caactcggcg aagcacggct
    18421 ggcggtgcag cgggacgggg tagtacgtct cggtggtgac accgttcgcg gcgaggtgcg
    18481 cgaccagctc gtcgcgccgc tcgacctcga tcaggtagac gtagaacacc gcgtcggtct
    18541 tgacctcgcg ctcgaccacg gtcggcagcc tgcgcacgcc ggggcagccg gtgagccgct
    18601 cggtgtaggc cgcggcgagt tcggcgcggc gggcgatgtc ggcgtcgagc cgggtcagct
    18661 tggcgagcag gatggcggcc tggaagtcgt ccatcttgct gttgaggccg ggcagcacgg
    18721 tctcgttgct gatgccgggg aagtgatcga tcgtgcggcc gtaccgcccg tggtggcgca
    18781 gcgcggcggc ggtctcggcg atccggtcgt cgttggtgat gaccgcgccc gcgtcgccca
    18841 gcgcgccgag ggtcttggtc gggaagaagg acagcacacc gccgatgccg agcagccccg
    18901 cgtgcacgcc gtcccagcgc atgccgatcg cctcggcgct gtcctcgacg acggtcagcg
    18961 cgtactgctc ggcgacctcc gtgatcgcgg ccatgtcggc gagctggctg aacaggtgca
    19021 ccggcatgat catccgggtg cggtcggtga tggcgtcggc cgccgaggcc ggatcgatgc
    19081 cgtaggtcac cgggtcgatg tcggcgaagg cgggccgccc gtgggcgagt gccaccgagg
    19141 acgccgacgc gacgaagctg aacgcgggga cgacgacctc gtcgcccggg ccgaggcccg
    19201 cggcgcgcag gagcaggacg agggcgtcgg tgccggagtt gactccgatg acgtgcgcgg
    19261 cgccgatgcg ctcggcgagc accgactcga actcggcgac gaggtggccg tgggagtact
    19321 tgccccggtc gatgaccgcg ttgaggttgg cctcggtgag cggccacagg tccgcgaacg
    19381 acgcggcctg ggtgaagaac gggacggtgc cgcctgcgcc gggggcctgc gcggcggcgg
    19441 gatccgcgaa ggtcgcggcg tgctccatgc gtgtcctttc cggactgcgt gttcttcgca
    19501 gacgcggctc agtggtgaaa cttcctcggc tgcggcgcga ccccattcca acctagccag
    19561 acggcattcg ttgaaccgca acggaatcca aagatcacac ggacgtgtgg cgcggtcggg
    19621 tccgcgttga caccgccggt ggccgccacc agtgttgacg ggcgtcaccc gatcccgcgc
    19681 aggaggcagc aaccgatgct gggcacgctc gtcgtgggac tcggtcgagc ggggacggag
    19741 ctgcacctgc cggtgctgcg ccggctgcgc cccgacgctc ccgtggtcgt cttcgacccc
    19801 caccggacgg cacggaccga cggtgtcacc gtcgccgact cgctgccgca cgccgcccgg
    19861 ctcatcgacc ccgcgaacac ggtcgtgcac ctgtgcaccc cgccgtcggc ccgggtcgcc
    19921 ccgctgaccg cgctcgccga gttgggcttc cgccgggtgc tggtcgagaa gccgctcgcc
    19981 gccgacgacc gcgacctgcg tgaggtgctg gcgctgcgcg aggccgcgcg cctggacctg
    20041 ctgccggtcg gccagtggcg ggccagcgaa ctgaccaggc ggctggcctc gatcctgcgc
    20101 gagcgcaggc tgggcaggcc tcggtcgatc accatcgtgc agagcaagcc ccggttcgcc
    20161 cgcaccgcgc tgggcgacga gcaccccagc gcgttcgacg tcgaagtgcc gcactcggtg
    20221 ctgctggcgc tgctgctcgc cggtccggcc gaggtcctcg gcgcgcactg ctcggacatg
    20281 ctcctcgggg atgaggtgta ccccgcgctc ggcggggccg tgctgcggct gagccacgcc
    20341 agtggcgtgc gcaccgagat ccgcaccgac ctcacgtccc cgatccgcga gcggaaggtc
    20401 accatcgacc tcgacggcgg cacggtggtc ggccacttcg cggtgagcgc cgccgacgac
    20461 cacgcgcagc tgcgggtcag cacccagggc cagcagctgc gctcggtgtt ccgcgacgac
    20521 tcactcggcg cgttcctcgc ccacgcctac cggcacttcg ccggcgagga ccgcatcacc
    20581 gacgaacccg acaccggcgc cgcggtcgtg gagctgatca gcgccgcgaa acggctctcc
    20641 ggagtggccg tgccggaagg ggcgagccgg tgatgtcgct gccggtcctc gcggggatcg
    20701 gcgacgaagc cggacccgaa ctcgccgacc aggtggccgc catcgccgca ctggagtggg
    20761 acgccatcga actgcgcacg gtcggcggca ccgcgatcgc cgacctcgac gaccgcgcgt
    20821 tcgacctggt ggcggccacg ctcgccgagc gcggcctgca caccgtgtgc gtcgactccc
    20881 gcatcggcga ctggtcgagc acgatcaccg gcgacttcgg ccgcgacctg gaggaactgc
    20941 gcaccctcgg cccccgctgc gccgcgctag gcacccggta cgtgcggatc atgtcgtacc
    21001 cgaacggcgg actggccgac gcggagtggg agcgccgggt g
//
