LOCUS       NZ_LT607411            26047 bp    DNA     circular CON 11-DEC-2024
DEFINITION  Micromonospora viridifaciens strain DSM 43909 chromosome I.
ACCESSION   NZ_LT607411
VERSION     NZ_LT607411.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora viridifaciens
  ORGANISM  Micromonospora viridifaciens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091545.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:27:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,508
            CDSs (total)                      :: 6,445
            Genes (coding)                    :: 6,270
            CDSs (with protein)               :: 6,270
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 175
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 83 of 175
            Pseudo Genes (incomplete)         :: 110 of 175
            Pseudo Genes (internal stop)      :: 8 of 175
            Pseudo Genes (multiple problems)  :: 25 of 175
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:55:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3612001
            Orig. end                         :: 3638048
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607411.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26047
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="14"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26047
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26047
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16047](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16047
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(622..1179)
                     /locus_tag="GA0074695_RS16215"
                     /old_locus_tag="GA0074695_3299"
     CDS             complement(622..1179)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287393.1"
                     /locus_tag="GA0074695_RS16215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3299"
                     /product="N-acetyltransferase"
                     /protein_id="WP_231934585.1"
                     /transl_table=11
                     /translation="MILAEAFMRDPVSEWIFPDEEHRAKSHPAFFGEFVNLVLEAGEIY
                     LAGEGAGVTLWLPVDGSDEPDEGQELLQTLEAAVGAEATKRFAVLDGLMAANHPSEPHW
                     YLPFIAVHPDQHSKGVGSALLRHKLTQLDEAGSAAYLEASSPRNATLYERHGFGFGPSI
                     LDLPDGPSLYPMWRNPARPVRG"
     misc_feature    1300..1315
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(1346..2317)
                     /locus_tag="GA0074695_RS16220"
                     /old_locus_tag="GA0074695_3300"
     CDS             complement(1346..2317)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0074695_RS16220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0074695_3300"
                     /product="hypothetical protein"
                     /protein_id="WP_157744489.1"
                     /transl_table=11
                     /translation="MPTAVAANAAVLPINDLGSGTYLGFQGGLYPAGRNTMPDAHRSAG
                     VNRALRVRPLDTTGTPSANGKYVLLSIGMSNTTQEFCSSETGGQCAPYSFIGQAAADPR
                     VNHDKLAIVDGAAGGQTADTWDSPTDANYDRVRDTRLAPLGLTERQVQVAWVKVANAGP
                     SASLPATNADAYRLVTQQGNILRALKKRYPNLQQVFFSSRIYAGYATTGLNPEPYAYET
                     GFGVKWVIQAQITQMSGGGTDPRAGNLAYDSAAPWAAWGPYLWANGLQPRSDGLTWERS
                     DFGSDGTHPSASGRQKVASMLLRFFATSPHTACWFTVGGTCG"
     misc_feature    complement(2406..2419)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(2423..3403)
                     /locus_tag="GA0074695_RS16225"
                     /old_locus_tag="GA0074695_3301"
     CDS             complement(2423..3403)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014068.5"
                     /locus_tag="GA0074695_RS16225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3301"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_089007051.1"
                     /transl_table=11
                     /translation="MPLDGPDVAMLAYAGAGSFDYVTVNEIFGVDYSPRFGSWYRTRTC
                     GVAPGPVDLDGGVTVRAAYGLDAAERADLLIVPGWTKEQEAPPQALLTTLRRAYRRGAR
                     IMSICTGAFVLGHAGLLDHRRVTTHWAKAPLLAALFPAATVDPRALFVDDHRVLTAAGM
                     SAGMDLALHVVRGDFGADAAATIARRLVLAGYRSGGQAQFVDSPLGADPADPLPDLLDW
                     MRRHLAQRRSLGSLAARVHMSPRTLARRFQRLTGMSPHQWLMRERILAAQRLLETGDES
                     VEQIAARTGIGSASNLRHSFRRELGVSPQAYRTTFRSRRNADQPG"
     gene            3634..4608
                     /locus_tag="GA0074695_RS16230"
                     /old_locus_tag="GA0074695_3302"
     CDS             3634..4608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473618.1"
                     /locus_tag="GA0074695_RS16230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3302"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_089007052.1"
                     /transl_table=11
                     /translation="MNETSPAFGRRTFLLAATAVTVTGAVGVADPASATARSGTGGPLV
                     ASRSVGAFEVTPLLDATGSFFLDRQAAFPAATPHDWDRARVVDPGAFGPGETWQLDFRC
                     YAVRGPRDRLMLVDAGVGPDGSPAGGWAPTPGRLPSELERAGIDPADVDTVVLTHLHED
                     HFGWSVGLDGTPLFPNARYVVQRREVEALPDGDAARAYVVDPLRTTGQLDEVDGVARLA
                     TGRGGAGGSVRVIPTPGHTPGHQSVVVDHGRDQVIITGDVLVHAVQLVDPEVAYRYEAD
                     PEVARRTRQRLLAAARARRAVLATAHLRQPWTEVPDPTGVRGQ"
     misc_feature    4207..4209
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4618..7197)
                     /locus_tag="GA0074695_RS16235"
                     /old_locus_tag="GA0074695_3303"
     CDS             complement(4618..7197)
                     /NRPS_PKS="Domain: NAD_binding_4 (6-249). E-value: 3.1e-44.
                     Score: 142.9. Matches aSDomain:
                     nrpspksdomains_GA0074695_RS16235_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019604.5"
                     /locus_tag="GA0074695_RS16235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3303"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_089007053.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.3e-42, bitscore:
                     142.9, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-27, bitscore:
                     94.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAHVVTGGTGFVGLALILELLRRTDDEVVCVVRPGTQDPDPRL
                     RRLLAEAASAYGRHVDLGRVRTVAGDVSRPGCGLAEPIRAPIADFWHSAASLRYEESAA
                     TEIFATNVDGTRHALDLADRLGAAAFNYISTAYVAGTRDGVITERLITPDGSNNAYERS
                     KAAAEALVHAHPGTATRILRPSIVVGDRGTRAVVGSYTGMYGFQRRLATFAHTLSVRAP
                     ERLSRPVRMLVDPATPLNLVPVDAVVEQLVGIATSASAARVFHLTNSTPPAAGAVLRQI
                     FALAGLPEPEYVTDPSQLDDTDRAFARGIEFYRSYLVGEKLFDRTNSDRALGRPDAGTM
                     PFPDDEVAAYGRWYLENVRRHRPSARPRPAAPALPAQPAAAPAATPAPDRPARIVLLGG
                     GYTSVWAYKSLRRRLGRALGRGDVEIVFVDPLGYHSFHGFTAEVLGGIIAEGHERSPLR
                     STCPGAQLIRGSAQRVDLARREVAVALAGTGGETLTLRYDHLVIGCGSHDDLARVEGFA
                     EHGWSLKHPDGSAAVRERLLAQVELAEASPDERLRRELLTVVVVGGGFTGVEMSATIAE
                     ILRGLRPRYRVLREVEPRVHLVHGGPDLLPQLRPRFTRLARYAHRQLVRSGVQVHLRAR
                     VVRVDKDGARLDDGSLLASRLVVSTLGQAVAPVPGTERLESRLGRLVTDDHLRVRGADG
                     RVWSGGDHAHIVHPVKGEPCPANALWAIKHGVWIGANVAATLRGRAPRRFTYRGLGQAA
                     SLGVGKGAVELYGVQVTGWLGWLMRAGFFLWFMPSRRQAVRCLVDLLGAPVLGRRLTAL
                     APSGQPIPRRGPERPAAVGRPPAERDELPPRQRERGRRERAPQPDPR"
     aSDomain        complement(6451..7179)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074695_RS16235_NAD_binding_4.
                     1"
                     /evalue="3.10E-44"
                     /label="GA0074695_RS16235_NAD_binding_4.1"
                     /locus_tag="GA0074695_RS16235"
                     /protein_end="249"
                     /protein_start="6"
                     /score="142.9"
                     /tool="antismash"
                     /translation="VTGGTGFVGLALILELLRRTDDEVVCVVRPGTQDPDPRLRRLLAE
                     AASAYGRHVDLGRVRTVAGDVSRPGCGLAEPIRAPIADFWHSAASLRYEESAATEIFAT
                     NVDGTRHALDLADRLGAAAFNYISTAYVAGTRDGVITERLITPDGSNNAYERSKAAAEA
                     LVHAHPGTATRILRPSIVVGDRGTRAVVGSYTGMYGFQRRLATFAHTLSVRAPERLSRP
                     VRMLVDPATPLNLVPVDAVVE"
     CDS_motif       complement(7120..7185)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074695_RS16235_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="GA0074695_RS16235"
                     /protein_end="26"
                     /protein_start="4"
                     /score="11.6"
                     /tool="antismash"
                     /translation="HVVTGGTGFVGLALILELLRRT"
     gene            7293..8095
                     /locus_tag="GA0074695_RS16240"
                     /old_locus_tag="GA0074695_3304"
     CDS             join(7293..7631,7634..8095)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="GA0074695_RS16240"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GA0074695_3304"
                     /product="IS5 family transposase"
                     /protein_id="WP_231935229.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MQQWVPDELWNLAGPLIPPPPRRRQGGGTPPIDARAVFAAIVYVL
                     TTGCAWRHLPPGFGVSRATAHRRFTAWTAAGLWRRLHVAALDQLGAQGLIDWSRATADA
                     AYVRAKKGALTGPSPVDRGKPGSKIHALSERGGLPLSVGVSAANTHDSRCLESLVQAIP
                     AVKSRRGPRRRRPDKLHADKGYDYPHLRRMLRQRGIRPRIARRGIDSPNRLGRHRWVIE
                     RTFAWLTGYRRLTIRYERNPGLYCAFLTLAAALTCHKRYLRLTT"
     gene            complement(8625..9464)
                     /locus_tag="GA0074695_RS16245"
                     /old_locus_tag="GA0074695_3305"
     CDS             complement(8625..9464)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459304.1"
                     /locus_tag="GA0074695_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3305"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_089010018.1"
                     /transl_table=11
                     /translation="MADTTSGVRPEQPPSARIDPSVPHPARRYDYWLGGKDNFAADRRS
                     GDAVAAAYPAIRTTVIENRRFMQRATRYLAGTAGVRQFLDIGTGIPTSPNLHEIAQEIA
                     ADSRVAYVDNDPIVLAHARALLTSKPEGATAYVDADLRDPERILSHPEVRATIDFDRPV
                     GLMLVAILHFLTDADDPHGITRRLIEALPSGSYVVISHATTDLVPREVAATAAPVTTTS
                     MIDMAFRTSGEVAAFLDGLELVPPGISPITEWHSDAPPEHRTPAAQASMYGVVARKP"
     misc_feature    complement(9802..9816)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            10001..10858
                     /gene="hpnC"
                     /locus_tag="GA0074695_RS16255"
                     /old_locus_tag="GA0074695_3306"
     CDS             10001..10858
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03464.1"
                     /locus_tag="GA0074695_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3306"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_197698165.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.2e-49, bitscore:
                     165.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.2e-46,
                     bitscore: 157.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRTAVAAVRRVEQARSRENFPVALRVLPGRYRRHLLAVYAYAR
                     QIDDIGDEPLPGTTDRVAALDAIEAELRSVYAGREVSHPVVRGLAPTVAECRLPLDALV
                     RLIEANRVDQRVTRYATFDQLVGYCNLSANPVGELVLHVFGQVDEARIALSDRICTALQ
                     LVEHLQDVAEDHRRGRVYLPAEDLDRFDVTEDDLARPSASRQLRELIEYEAERARAWLD
                     AGAPLVAALHGWARLAVSGYLAGGRATLDALAAAGHDPLSATVRPRGRRVLHRWLAATV
                     RSAG"
     gene            10855..11724
                     /gene="hpnD"
                     /locus_tag="GA0074695_RS16260"
                     /old_locus_tag="GA0074695_3307"
     CDS             10855..11724
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152784.1"
                     /locus_tag="GA0074695_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3307"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_089007056.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.7e-56, bitscore:
                     188.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.7e-65,
                     bitscore: 219.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTICDVDTAYRRCEQITRSRAANFAYGIRLLPPVRRRALSAIYA
                     TARRIDDIGDGTMAPDEKLDHLARTREALHQLPGNDDGDPVLTALADAAVRLPIPLAAF
                     DELIDGCAADVTGRTYATFDDLHWYCRCVAGSIGRLSLGVFGVTDRVRAEPLADALGVA
                     LQLTNILRDLVEDRADGRIYLPAEDLDRFGCTLRLEGGRFTDPPDRLIELVRFQAQRAA
                     QWYDTGLRLLPLLDRRSAACTAAMAGIYRRLLTRIAADPLAVTRSRVSLPVREKAWVAA
                     RALVGRTT"
     gene            11721..13088
                     /gene="hpnE"
                     /locus_tag="GA0074695_RS16265"
                     /old_locus_tag="GA0074695_3308"
     CDS             11721..13088
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076662.1"
                     /locus_tag="GA0074695_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3308"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_089007057.1"
                     /sec_met_domain="DAO (E-value: 1.4e-07, bitscore: 30.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPQVPGGGGSVCVIGGGLAGIAAAIRLADQGLPVTLLESRPEL
                     GGATYSFRRDGLTVDTGQHVFLRCYHAYRGLLDRLGVTDDAQVQPRFAVPVLLPGRAPH
                     LLARGRLPAPAHLLPALAAYRLLTPAERLAAVRAAAALRHVDPDLPATDARSFGEWLAG
                     HGQGDRAVRRLWDLVTVAALNLPSAHASLALAARVFRTGLLDATDAGDIGRPTVPLTEL
                     HAVPARRLLHQLGARVRTRSRVRWIHPESDGFRVGLSDGEIATDAVVLAVPHHVAAALV
                     PPAAAPDAGDWHRLGAAPIVNVHLRYARRITELAMAAAVESPAQWIFTRPGSDDAQHVV
                     VSLSAADTQIDRPAAELVAVQRAALAALFPAARHTPVRDAFVTREPRATFRQAPGTRAY
                     RPATTTRLPGLVLAGAWTDTGWPDTMEGAVRSGQEAADVVARQLASRPRHHTEAAR"
     gene            13085..14092
                     /locus_tag="GA0074695_RS16270"
                     /old_locus_tag="GA0074695_3309"
     CDS             13085..14092
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020522065.1"
                     /locus_tag="GA0074695_RS16270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3309"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_089007058.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.8e-61, bitscore:
                     204.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAHSDRTSQIHIHVEPAIRVLLDRLDPGNRLVAGYQMGYWNAD
                     GSPAVRRGKGLRPALALLSAQAAGADTEAGVPAAAAVELTHNFSLLHDDVMDGDTERRH
                     RPTAWTVFGVSRAILAGDALIGLAYEALAEVTGGEPAVRRLALDVRALIRGQAADLAFE
                     HRDDVTLDECLAMAGDKTAALLSGSCALGALLCGGPAGLVDGLSRFGFHLGLAFQLVDD
                     LLGIWGDPRRTGKPVGSDLRARKRTIPVVRAVTDGGSAGRALAELYRSPAPLTDDDVAR
                     ATGLIEATGARDWTRQRAARETERARAELAALDLPDHVRRELADLTTFITGRDH"
     gene            14092..16047
                     /gene="shc"
                     /locus_tag="GA0074695_RS16275"
                     /old_locus_tag="GA0074695_3310"
     CDS             14092..16047
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01507.1"
                     /locus_tag="GA0074695_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3310"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_089007059.1"
                     /sec_met_domain="T2TS (E-value: 5.4e-147, bitscore: 489.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELLSPKPTGSVVTAPLAGGDTTSDAAREALRRARDHLLGLQDD
                     AGWWKGDLATNVTMDAEDLLLRQFLGIRTAEQTAESARWIRSQQRPDGSWATFHGGPGD
                     LSTTIEAYLALRLAGDAPEAPHMATAAAFVRDHGGLVASRVFTRFWLALFGQWPWSRLP
                     AVPPELVLLPPWMPFNVYDFACWARQTIVPLSIVRALRPVRDLGFTVDELRTADAPPRP
                     PRLLTRPGVLHRLDRLAAGYERIARGPLRRNALRRAAEWIVARQEADGSWGGIQPPWVY
                     SLMALHLLGYPLNHPVLRSGLAGLERFTVRQPSPDGPMRWLEACQSPVWDTALAVTALS
                     DAGLPAGHPALARAGIWLLSEEIRVRGDWAVRRPHVPAGGWAFEFDNDGYADTDDTAEV
                     IMALRRTNLPADAAVLRATRWLLGMQCRDGGWAAFDADNTRKVLGDLPFCDFGEVIDPP
                     SADVTAHIVEALAAENFADTVPVRRGVAWLLRAQEPDGSWFGRWGANHVYGTGAVVPAL
                     VAAGLRPGHPAIRRAVDWLLAHQNPDGGWGEDLRSYRDPAWVGCGESTASQTAWALLAL
                     HAAGHGPGEAATRGVRWLVDTQRPDGGWDEPQYTGTGFPGDFYINYGLYRLVFPISALG
                     RILDARATGLDAEALA"
     gene            16044..17597
                     /gene="ispH"
                     /locus_tag="GA0074695_RS34370"
                     /old_locus_tag="GA0074695_3311"
     CDS             16044..17597
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076659.1"
                     /locus_tag="GA0074695_RS34370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3311"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_231934586.1"
                     /transl_table=11
                     /translation="MTAPAGSPPWTLYAPMRAEASALRRGLTNRAFPGRPALRRTGVGP
                     RRARAAAARRPAGVAPVAVAGIGGGLAPGLAPGDVVVASEVRVDPLAPGDPPRVLRLPD
                     APLLAAALRRRGLRVHVGPVLSTDRLVDGAARSRLAATGALVADCESAWLLAGRGDRPA
                     ACVRVVADTSAGSLYRPATLGRVRTALRVLPVVASALAEWAAASSLRQVVLASPRSFCA
                     GVERAIAVVEQALRQHGPPVYVRKQIVHNARVVADLRARGAVFVDELDEVPDGGVTVFS
                     AHGVAPAVRREAAQRRLPVIDATCPLVAKVHAEARRFAGRGDTVLLIGHAGHEETDGTL
                     GEAPGRIRLVPDPAAAESVRVDDPDRVSYLVQTTLATDEAAGVVEALRRRFPALAGPDS
                     DDICYATTNRQQAVTEVAARAEVVLVVGSDNSSNSRRLVEVAERAGAAAYLVEDVSRVD
                     LRWLAGAATIGVSAGASAPPGLVDEVVAALTALGAREVSEHTTTVEDVAFTLPKEVRQP
                     "
     misc_feature    16392..16394
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17600..18595
                     /gene="hpnH"
                     /locus_tag="GA0074695_RS16285"
                     /old_locus_tag="GA0074695_3312"
     CDS             17600..18595
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076658.1"
                     /locus_tag="GA0074695_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3312"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_231935272.1"
                     /sec_met_domain="PF04055 (E-value: 1.2e-18, bitscore: 66.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.1e-08, bitscore: 31.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRQSLRIASYLMEQKMRGRKRFPLLLELEPLFACNLSCAGCGK
                     IQQPANLLKRRMPVEQALAAVEECGAPMVSIAGGEPLMHPEIDTIVAELVRRKKFVFLC
                     TNAVLLPKKIEKFRPSPYFAFTVHIDGLRERHDAAVCKDGVFDAAVAAVRDAKRRGFRV
                     TTNTTFFNTDTPQTVIEVLDYLNDDLRVDEMMLSPAYAYEKAPDQEHFLGVTETHELFR
                     KAFGGGRRRRWRLNHSPLFLDFLEGKVDFPCTAWAIPSYSLLGWQRPCYLMADGYAASY
                     RELLDSTDWDSYGRGRDARCANCMAHCGYEPTAVLATMSSLRQSLRAMRN"
     gene            complement(18620..19369)
                     /locus_tag="GA0074695_RS16290"
                     /old_locus_tag="GA0074695_3313"
     CDS             complement(18620..19369)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-173). E-value: 6.8e-17. Score:
                     53.9. Matches aSDomain:
                     nrpspksdomains_GA0074695_RS16290_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.5"
                     /locus_tag="GA0074695_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3313"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_089007061.1"
                     /sec_met_domain="adh_short (E-value: 8.7e-32, bitscore:
                     109.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTGAVVLVTGASSGIGAAVVRRLARAGSQVVAVGRHPGRLARL
                     AAETGAAALPADLARPGAGRELAERVLARHPRVDVLVNNAGVGWAGRFTEMPDAVTDEL
                     LAVNLHAPIELTRALLPGMRRPGGHLAFVGSIAGRLGVGGEAVYAASKAGLDIFAQSLR
                     LELAPHRITVSVVVPGVVDTPFFDRRGQAYRRRRPRPLPPERVADALAAAIARDRAEVY
                     VPGWLRLPVAVRGLQPAVYRRLAARFG"
     aSDomain        complement(18851..19351)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074695_RS16290_PKS_KR.1"
                     /evalue="6.80E-17"
                     /label="GA0074695_RS16290_PKS_KR.1"
                     /locus_tag="GA0074695_RS16290"
                     /protein_end="173"
                     /protein_start="6"
                     /score="53.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAVVRRLARAGSQVVAVGRHPGRLARLAAETGA
                     AALPADLARPGAGRELAERVLARHPRVDVLVNNAGVGWAGRFTEMPDAVTDELLAVNLH
                     APIELTRALLPGMRRPGGHLAFVGSIAGRLGVGGEAVYAASKAGLDIFAQSLRLELAPH
                     RITV"
     CDS_motif       complement(19214..19351)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074695_RS16290_0001"
                     /evalue="1.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="GA0074695_RS16290"
                     /protein_end="52"
                     /protein_start="6"
                     /score="14.8"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAVVRRLARAGSQVVAVGRHPGRLARLAAETGA
                     A"
     gene            complement(19360..22035)
                     /locus_tag="GA0074695_RS16295"
                     /old_locus_tag="GA0074695_3314"
     CDS             complement(19360..22035)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014998.5"
                     /locus_tag="GA0074695_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3314"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_089007062.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 3.4e-05,
                     bitscore: 22.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATMRPAQPLAVRQSTATGGAEAPSPATPEGGTEPFARRVLVVS
                     ADIGGGHDATGRALAERVRTLWPGSRVGWVDTLDVMGPGVGRSFRRTYRTNVAATPWLY
                     EFFWASIWRHRWFATASKWFTGAWAGRRLAPVVEAFDPDLIVSTYPLGSAGLAWLRRRR
                     GLGVPVGAWVCDFAPHPSWVYSELDLDLVVHPAAVPVAAVAAPGVRLGVCAPPVLDRFH
                     PGDRVEAARRSGLDPARSAVVVACGSYGFGHVEEAIDALVGIGDPVQVVAVCGRNERLV
                     ERLAALRLPPDRLLVRQWVDDMPTLLRAAGLVVTNAGGATALEAWASGTPIVMYRPIAA
                     HGVANAALMTAAGVAETAHSPNALVACVRSRLVGGQAAGATAPAAHPHLPDLGLPALAD
                     ARGPVGDTRPASVAGRPGMDRLPPVGRPASWPLRPQDAFFLHVQSERVAQHIGTVLELG
                     PRADGRAVAAADLVALLAARLPAIATLRRRLDNRGRWRRPGWIVDRYVDPAAHVDEVTV
                     APGDDGGAALDRFWSEPLAADRPLWRILLVSGLPDRRTRVAVKVHHSLGDGMSVIGILG
                     RLLDRPAGRAAGPQRPAPFTPEQATVARPERGERLRRLGLTARGLARLATQGPAPVTGF
                     NRPIGSPERRLVTASLPAAEVLRAARACRAHASELMLALTATALGAVRPAGAPPRLRAM
                     FAVSRNPRRRAPTHGNWTGAVNLDLPLGRCSPQDRVVAVRQSLRTALDSGEAEAAGLVM
                     RTMGALPAPLHAALARRVYTSRHLNVIVSYMALPWDSRLLAGAPLRAAIPVVALAEGVP
                     LGVGVLRCRNAFEIGVLLDESLADIGTAFVAALRTSLTELLDEVEAGDEGGAGPGGGSV
                     ERVPEGAPAGRSRSGVPRCA"
     misc_feature    complement(22127..22143)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.28"
                     /tool="antismash"
     gene            22184..22897
                     /locus_tag="GA0074695_RS16300"
                     /old_locus_tag="GA0074695_3315"
     CDS             22184..22897
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013718.5"
                     /locus_tag="GA0074695_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3315"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_089007063.1"
                     /transl_table=11
                     /translation="MATGRPETGRGRPRPLGVPVLAPVPGGWWFDGLLVAAFAALTAAL
                     VWWSPLLRLDLAVRDWCDAHRPSPVHVLMQAFDYLGQGGGLIVVTMLVAGWLAWQHRTA
                     RPIVLAGLAPIISTLLIVGLKRWTSRGAPHHGSVRLFTHGPEVEYPSGHVSNAIVYYVV
                     LAVLLAPYLAVPARRIVQWLPGVLTFIGTTYVSYHWLTDSMGGYLLGLLIARLLLRVPW
                     RTVPLPRWLDRASAC"
     gene            22891..23772
                     /locus_tag="GA0074695_RS16305"
                     /old_locus_tag="GA0074695_3316"
     CDS             22891..23772
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038012.1"
                     /locus_tag="GA0074695_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3316"
                     /product="DMT family transporter"
                     /protein_id="WP_157744490.1"
                     /transl_table=11
                     /translation="MLSEVARLAAGAPLALVAAAAFGASSLLQFRASRQVPEERAGRPR
                     LLIRLIRLRGWRWSAVLAAMAFACQVAALSLVPLILVQPLLVTGLVWYVLLFAGAQHRR
                     PDPRILLESGLCLLGLGAFLAFARPTHQQGRGLDSFGSAALLGVAVILGVGLCLVGALK
                     LGRKWRPLPLAVAAGICYGVTAGLISSLGLQSEPSSLAVFGQWQTYAIAVLGPFGVLLS
                     QNAYQAGPMGAPALATITVTDPLVSIAVGLLWLDERIRTGTWVVLGEVLAVLVVVVAVS
                     LLARRAPHVAGA"
     gene            23877..24326
                     /locus_tag="GA0074695_RS16310"
                     /old_locus_tag="GA0074695_3317"
     CDS             23877..24326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461467.1"
                     /locus_tag="GA0074695_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_3317"
                     /product="VOC family protein"
                     /protein_id="WP_089007065.1"
                     /transl_table=11
                     /translation="MTNEAPDYFRPEHGMVLTHLLIVRDVDRSREFYRQVLGATVIRER
                     EPAILRFHNGYLVINNEGGPTDDKPTVRAQAPADPDSLSCALNIRVTDVRAVYEQWRSR
                     GGQFLTEPKDHGVEIRCYLRDPDGYLIELGQATGILAQLSGTPAG"
     misc_feature    24425..24439
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(25075..25090)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    25349..25363
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.71"
                     /tool="antismash"
ORIGIN
        1 ggcaggctga tcggccaggg cccgcgggcc cagggcacga tcacggtcag cccggacaag
       61 gccgagcacc ggatcgagct ggacgtggcc cgcaaggcgg actggtggac cacctccacc
      121 gagacccaca ccgcctggac cctccgatcg aagggctcca cctcgggccc ggtggtgctg
      181 ccgctgctgc aggtcgacta caacgtcccg gtggacctgc tcaacaccac cgcacagccg
      241 agcaaccggc agggcccgct gaccctcggt ctcaccgtcg gccaccaggt cggcgccgac
      301 ggcccggcag tccgcggcgc caaggtgtcg atctcgtacg acgacggcaa gacctggcag
      361 aagcgccccg tccgaggcct cgacggcggc cggttcgagg tgaccctcga caaccgcgac
      421 ccggcggaga ccaacggttt cgtggctctg cgggtcgagg cgtgggatgc cgacaacaac
      481 cggatcgagc agacgatcat ccgggcctgg cagctgccgc ccgcccgctg agtccatgac
      541 gctccggtag acgtggttgg ccggttgacg acggcggtcg tcaaccggtc aaccgctcta
      601 cagtcgagtt ggcgacgtct ttcagccccg caccggtcgg gcaggatttc gccacatcgg
      661 atagagactc gggccgtccg gtagatccag gatggacgga ccgaacccga acccgtgccg
      721 ctcgtagagc gttgcgttgc gcggcgaact cgcctcgaga taggccgccg agccggcttc
      781 gtcgagttgg gtgagcttgt gccggagcag ggccgaaccc acgcccttgc tgtgctggtc
      841 agggtgcacc gcgatgaacg gcaggtacca gtgcggctcg ctcgggtggt tggccgccat
      901 cagcccgtcg aggacggcga accgcttggt cgcctccgcg ccgacggcgg cttccagcgt
      961 ctgcagcagt tcctgcccct cgtcgggctc gtcgctgccg tcgacgggca gccacagggt
     1021 gacgcccgcg ccctcgccgg ccagatagat ctcgcccgcc tcgaggacga ggttgacgaa
     1081 ctccccgaag aacgccggat gtgacttcgc ccgatgctcc tcgtccggga agatccactc
     1141 gctgaccggg tcacgcatga acgcttccgc caggatcatc ccgacgagcc cggcgtcagc
     1201 gctcgatgct cgtcggatgt ctccctgcca acccaccact ctcactcccc acgctggcgc
     1261 cattgatcga tgagcgccga gtaggttatc agccgcggcg tcaccgcatg gtcaccgaag
     1321 gtccgcagtg gaccgctgaa cggcttcacc cgcaggtgcc gccgacggtg aaccagcagg
     1381 cggtgtgggg cgaggtcgcg aagaagcgga gcagcatgct cgccaccttc tgccggccgg
     1441 aggcggacgg atgtgtcccg tcggagccga agtccgaccg ctcccaggtg agcccgtcgg
     1501 agcggggctg gaggccgttc gcccacaggt acggtcccca ggccgcccac ggcgcggcgc
     1561 tgtcgtaggc caggttgccg gcccgaggat cggtgccgcc gcccgacatc tgggtgatct
     1621 gcgcctggat cacccacttg acgccgaagc cggtctcata ggcatagggc tccgggttca
     1681 ggccggtggt ggcgtacccg gcgtagatcc ggctggagaa gaagacctgc tgcaggttgg
     1741 gatagcgctt cttcagcgcg cggaggatgt tgccctgctg ggtcacgagc cggtacgcgt
     1801 cggcgttggt ggcgggcagg gacgccgacg ggccggcgtt ggcgaccttc acccaggcga
     1861 cctgcacctg ccgctcggtc aggccgagcg gcgccagcct cgtgtcccgg acccggtcgt
     1921 agttggcgtc ggtgggggag tcccaggtgt ccgcggtctg gccgcccgcg gcgccgtcga
     1981 cgatggcgag cttgtcgtgg ttgacccgcg ggtccgcggc ggcctggccg atgaaggagt
     2041 acggcgcgca ctgcccgccg gtctcggacg agcagaactc ctgggtggtg ttggacatgc
     2101 cgatggagag cagcacgtac ttgccgttgg cgctcggcgt gccggtggtg tcgagtggac
     2161 gtacccggag ggctcggttg acaccggccg accggtgggc gtcgggcatg gtgttcctgc
     2221 cggccggata cagtccgccc tggaatccga ggtaggtgcc gctgccgagg tcgttgatgg
     2281 gtagcacggc ggcgttggcg gccaccgcag tgggcatgcc gacgaccgtg gccgtcacga
     2341 ggacggtcag tatcgccagg aggcgacgag catcgataat catggcgccg aacctagggg
     2401 acgtagtgat atcggtcaat gactagccgg gttggtcggc gttgcgccgg gagcggaacg
     2461 tggtgcggta cgcctgaggc gagacgccga gctcacgacg gaagctgtgc cgcaggttgc
     2521 tggccgagcc gatcccggtc cgggcggcga tctgttcgac cgactcgtcg ccggtctcga
     2581 gcagccgctg cgcggccagt atccgctcgc gcatgagcca ctggtgcggg ctcattccgg
     2641 tgaggcgttg gaaacgccgg gccagggtgc gcgggctcat gtgcacccgt gcggccagcg
     2701 agcccagcga ccgccgctgc gccaggtgcc ggcgcatcca gtccagcaga tccggcagcg
     2761 gatcagccgg atcggcgccc agcggtgagt cgacgaactg cgcctggccc ccgctgcggt
     2821 agccggccag caccagccgg cgggcgatgg tggccgcggc gtccgcgccg aagtcaccgc
     2881 gtacgacgtg cagcgcgaga tccatccccg ccgacatgcc cgccgccgtc agcacgcggt
     2941 ggtcgtcgac gaacagtgcg cgcgggtcca cggtcgcggc cgggaacagc gcggcgagca
     3001 gcggggcctt cgcccagtgc gtggtgaccc gccggtgatc gagcaggccg gcgtgaccga
     3061 gcacgaacgc cccggtgcag atcgacatga tccgcgcccc gcgccgatac gcccggcgca
     3121 gggtcgtcag cagcgcctgc ggcggcgcct cctgctcctt cgtccacccg ggaacgatca
     3181 gcaggtcggc ccgttccgct gcgtcgaggc cgtacgccgc ccggacggtg accccgccgt
     3241 cgaggtcgac cggccccggc gccacgccac acgtgcgggt ccggtaccac gatccgaatc
     3301 ggggggagta gtcgacgccg aagatctcgt tgaccgtcac gtagtcgaag ctccccgcgc
     3361 cggcgtacgc cagcatggcg acgtcgggcc cgtccagcgg catcgggcga cctcctccgc
     3421 tccgcacgcg tactcccgcg gctgggcggg atcggattgg tggcaccgat cctaagaacc
     3481 gcagcggggc cgaacggcgg tgatatccgg tcacctgtcg gcaggatctg gtccaccttc
     3541 ccccacgccg gcgccggcgc gtacctcccg gtcctaacgt cgggccccga ggcgccgggt
     3601 gcgtcgaccc ggccctgacg agaggcggac ctgatgaatg agacttcccc cgcgttcggg
     3661 cgacggacct tcctgctcgc cgccaccgcc gtgacggtca ccggcgcggt gggcgtcgcc
     3721 gacccggcga gcgccaccgc gcgcagcggg acagggggac cgctggtggc gtcacggtcg
     3781 gtcggcgcgt tcgaggtgac tccgttgctc gacgccaccg ggtcgttctt cctcgaccgg
     3841 caggcggcgt tccctgcggc gacgccgcac gactgggacc gcgcccgggt cgtcgacccc
     3901 ggcgccttcg gccccgggga gacctggcag ctcgacttcc gctgctacgc cgtccggggg
     3961 ccgcgcgacc ggctgatgct ggtcgacgcc ggggtgggac ccgacggcag cccggccggg
     4021 ggctgggcac cgacgcccgg ccggctcccg tccgagctcg agcgcgccgg gatcgacccg
     4081 gcggacgtcg acacggtggt gctgacccac ctgcacgagg accacttcgg ctggtccgtc
     4141 gggctggacg gcacaccgct gttccccaac gcccggtacg tcgtccagcg ccgcgaggtg
     4201 gaggcgttac cggacggcga cgcggcccgg gcgtacgtcg tcgacccgct gcgcaccacc
     4261 ggccagctcg acgaggtcga cggggtcgcc cgcctcgcca ccggccgggg cggggcgggc
     4321 gggtcggtcc gcgtcatccc caccccgggg cacacgccgg gtcaccagtc ggtggtcgtc
     4381 gaccatggcc gcgatcaggt gatcatcacc ggcgacgtgc tggtccatgc ggtccaactc
     4441 gtcgaccccg aggtggccta ccggtacgag gccgaccccg aggtcgcccg ccggacccgt
     4501 cagcgactcc tcgccgcggc ccgcgcccgc cgtgctgtgc tggccaccgc gcacctgcgg
     4561 cagccgtgga ctgaggtgcc tgacccgacc ggcgtgcggg ggcagtgaca cccacggtca
     4621 ccgagggtcc ggctggggcg cgcgctcgcg tcggccccgt tcccgctggc gaggcggcag
     4681 ctcatcgcgc tcggcgggcg ggcggcccac cgccgcgggc cgctccgggc cccggcgcgg
     4741 gatcggctgg ccggacgggg ccagtgcggt cagccgccgc cccagcacgg gcgcgccgag
     4801 caggtccacg aggcagcgta cggcctgccg tcgggacggc atgaaccaga ggaagaaccc
     4861 ggcccgcatc agccagccga gccagccggt gacctgcacc ccgtacagct cgacggcgcc
     4921 cttgccgacg cccaggctcg ccgcctggcc caggccccgg taggtgaacc ggcggggtgc
     4981 ccggccgcgc agcgtcgccg cgacgttcgc cccgatccac accccgtgct tgatcgccca
     5041 cagcgcgttc gcggggcacg gttcgccctt gaccgggtgg acgatgtggg cgtggtcgcc
     5101 gccggaccag acccgtccgt cggcgccgcg tacccgcagg tggtcgtcgg tgaccaggcg
     5161 gccgaggcgc gactccagcc gttccgtgcc gggcaccggg gccaccgcct ggcccaacgt
     5221 cgacacgacc agccggctgg cgagcaacga cccgtcgtcg aggcgggcgc cgtccttgtc
     5281 gacccgcacc acgcgggccc gcaggtgcac ctgtacgccg gagcgcacga gctggcggtg
     5341 cgcgtaccgg gccagccggg tgaaccgggg gcgcaactgc ggcagcaggt ccgggccgcc
     5401 gtgcacgagg tggacccgcg gctcgacctc gcgcagcacc cggtagcggg ggcgcaggcc
     5461 gcgcaggatc tcggcgatgg tggccgacat ctccacgccg gtgaacccgc ccccgaccac
     5521 gaccaccgtg agcagttccc ggcgcaaccg ctcgtccggg ctcgcctcgg ccaactccac
     5581 ctgtgccaac agccgttccc gcacggccgc ggagccgtcc gggtgcttca gcgaccagcc
     5641 gtgctcggcg aacccctcga cccgggccag gtcgtcgtgg ctgccgcagc cgatgacgag
     5701 gtggtcgtag cgcagggtca gggtttcccc gccggtgccg gccagggcca cggcgacctc
     5761 gcgccgagcc aggtcgacgc gctgtgcgct gccgcggatc aactgggcgc cggggcaggt
     5821 gctccgcagc gggctccgct cgtgcccctc ggcgatgatg ccgccgagga cctccgcggt
     5881 gaagccgtgg aacgagtggt aaccgagcgg gtcgacgaag acgatctcca cgtctccccg
     5941 gcccaacgcg cggcccagcc ggcgccgcag cgacttgtac gcccacaccg acgtgtagcc
     6001 gccgccgagc agcacgatcc gggccgggcg atccggggcc ggcgtggcgg ccggggccgc
     6061 ggccggctgg gcgggcagcg cgggtgcggc cgggcgcggc cgggccgacg gccggtggcg
     6121 ccggacgttc tccaggtacc agcggccgta ggcggcgacc tcgtcgtcgg ggaacggcat
     6181 cgtccccgcg tcgggccggc ccagcgcccg gtcgctgttg gtccggtcga agagcttctc
     6241 gccgaccagg tacgaccggt agaactcgat gcctctggcg aacgcccggt cggtgtcgtc
     6301 gagctgggac gggtcggtga cgtactccgg ctcgggcagc ccggccagcg cgaagatctg
     6361 ccgcagcacg gcgccggcgg ccggcggggt cgagttggtg aggtggaaga ccctcgccgc
     6421 gctggccgag gtggcgatgc cgaccagctg ctcgaccacc gcgtcgacgg gtacgaggtt
     6481 cagcggcgtg gccgggtcga ccagcatccg gacgggccgg ctcagccgtt cgggcgcccg
     6541 gaccgacagc gtgtgcgcga aggtggcgag ccggcgctgg aagccgtaca tcccggtgta
     6601 gctgccgacg accgcccggg tgccgcggtc gccgaccacg atgctgggcc gcaggatgcg
     6661 ggtggccgtg ccggggtggg cgtgcaccag cgcctcggcg gccgccttgc tgcgctcgta
     6721 ggcgttgttg ctgccgtcgg gcgtgatgag tcgttcggtg atcaccccgt cgcgggtgcc
     6781 cgcgacgtag gcggtgctga tgtagttgaa ggcggcggcg ccgagccggt cggcgaggtc
     6841 gagcgcgtgc cgggtgccgt cgacgttggt ggcgaagatc tccgtcgcgg cggactcctc
     6901 gtagcgcagc gaggcggcgc tgtgccagaa gtccgcgatc ggcgcacgga tcggttccgc
     6961 caggccgcaa cccggccggc tgacatcgcc cgcgacggtg cgtacccgtc cgaggtcgac
     7021 gtgccggccg tacgcgctcg ccgcctcggc caacagacgg cgtagccgcg ggtcggggtc
     7081 ctgcgtaccg ggccgcacca cgcagacgac ctcgtcatcg gtgcgccgca gcaactccag
     7141 gatgagcgcc aacccgacga agccggtgcc gccggtcacg acatgtgctc tgttcatgac
     7201 gaaattcccc cacaccgcga gtaagagcgt gtctcgggtg gcggtcgggt ggcctggggt
     7261 ggtagatcac ttttactgtg gacgaacggt tgatccagca gtgggtgcct gacgagttgt
     7321 ggaacctggc cggtccgttg atcccgcccc cgcctcgacg tcggcagggc ggaggtacac
     7381 cgccgatcga cgcgcgggcg gtgttcgccg cgatcgtgta cgtcctgacc accggttgcg
     7441 cgtggcggca cctaccgccc gggttcggcg tgtccagagc caccgcgcat cgccgattca
     7501 cggcgtggac tgccgccgga ctgtggcggc ggcttcacgt cgccgcgttg gaccagctcg
     7561 gcgcgcaagg gctgatcgac tggtcccgtg ccaccgccga cgccgcctac gtgcgggcga
     7621 aaaagggggc ggtctgaccg gtccgagccc ggtcgaccga ggcaagcccg gcagcaagat
     7681 ccacgctcta tccgaacgcg gcgggctccc gctgtccgtg ggcgtgtccg cggcgaacac
     7741 ccacgacagc cgctgcctgg aatccctggt ccaggccatc cccgccgtca agtcccggcg
     7801 cggcccccgc cggcgacggc cggacaagct gcacgccgac aagggatacg actacccgca
     7861 cctgcggcgc atgctgcgac agcgcggcat ccgaccccgc atcgcccgcc gcggcatcga
     7921 ttccccaaac cgcctcgggc ggcaccggtg ggtcatcgag cggaccttcg cctggctcac
     7981 cggctaccgc cggctgacca tccgatacga acgcaacccc ggcctgtact gcgcctttct
     8041 caccctcgcc gccgcactca cctgtcacaa gcgctacctc agactcacca cctgagacac
     8101 gctctaagta caggcgaagc taagggcgga actcgccacc ggtcgcggtc ttgtcagaca
     8161 gctgccaggc gtcctggccg aacggccatc cggacctcca tcggtattcc gcatggctcg
     8221 ccgttccggc cgggccagcc ggaggcgggg ccgccggagg acgattggtg tccggcgaga
     8281 atctgcaaat gttccgacag cccgttaccg ctgtgccgac ccacgtcatg gcagctcaga
     8341 tcgccgctcg tgcgttcgcc gcggtggccg gcccggctgc ggaacacgga tccggaggcc
     8401 cggagcgaag gcgtgccgag cgcgggcgaa cgcgttgaga tgtcgaaccc gtttgctgga
     8461 accgccggat caggaatgga ggttcaccgg gtcgccacgc cgaatctcct cgccgaaggt
     8521 gaagaaatgt ccgcgcggcg cgaattgggt ccgaaatggc gccacgttcc gctttcggcc
     8581 ggctgcgcgc cgtggtcgga aaggcgagga ggaacgcgtg cgactcaggg cttgcgcgcg
     8641 accaccccgt acatggacgc ctgcgcggcc ggcgtccggt gctccggcgg agcgtccgag
     8701 tgccactcgg tgatcgggct gatgccgggc gggacgagct ccaggccgtc gaggaacgcg
     8761 gcgacctcgc cgctggttcg gaaggccatg tcgatcatgc tggtcgtggt gaccggcgcc
     8821 gcggtggcgg cgacctctcg cggcacgaga tcggtggtgg cgtgcgagat caccacgtag
     8881 ctcccggacg ggagggcctc gatcagccga cgggtgatcc cgtggggatc gtcggcgtcg
     8941 gtcaggaaat gcaggatcgc aacgagcatg agcccgaccg gtcggtcgaa gtcgatcgtg
     9001 gcccgtacct cgggatggct caggatccgc tccgggtcgc gcaggtccgc gtcgacgtac
     9061 gcggtggcgc cctccggttt gctggtcagc agggcgcggg cgtgcgcgag cacgataggg
     9121 tcgttgtcga cgtacgcgac ccgcgagtcg gcggcgatct cctgcgcgat ctcgtgcagg
     9181 ttggggctgg tcgggatgcc cgtcccgatg tcgaggaact gccggacgcc ggccgtcccg
     9241 gccaggtacc gggtggcccg ctgcatgaac cgccggttct cgatcaccgt cgtccggatc
     9301 gccgggtacg cggcggcgac cgcgtcgccg gaccgtcggt ccgccgcgaa gttgtccttg
     9361 ccgccgagcc agtagtcgta gcggcgggcc ggatgcggca cggacggatc gatccgcgcc
     9421 gacggtggct gctccgggcg tacccccgac gtcgtgtccg ccatcgcgac ctccccgtcc
     9481 atagtgggcg tttcccggga tcttagcggc tggacccgcc accggaggcc cctcccgcgg
     9541 cgcgcacccg ctcgcccact ccaccggcag gccccgcccg ccggctcctg atctccgcca
     9601 gccggcggcg gcccgacccg ccgctgggcg agcccggtcg gagatcgtcg ccggccagcg
     9661 gcggggccgg gcggagagcc gacggaggct gctgcgcctc gtgcccgagc tggccgtccc
     9721 gaccgcgccc gaggccgtcc ggcggctgcc tcggctcagg ggatttggcg ggaatcaggg
     9781 aattggcccc gatctgcatg gttaaggtga attccagctg gctctggggg atcggtgttt
     9841 ccccggcgcc acccgcgccg cccatcgccg cgcgcggtcc tgcaccgacc gctccagccc
     9901 gcgtcgggcg ggacgcccac gacaccggcg gcgtccgcac cgggcgctgc ccggacgagc
     9961 agacaccgtc ggccccgtgc ccggccagga aggaatgctg atgagccaac gcacggccgt
    10021 cgcagcggta cgccgggtcg agcaggcccg gtcgcgggag aactttccgg tcgcgttgcg
    10081 ggtcctgccc ggccgatacc gtcgtcacct gctcgcggtc tacgcctacg cccggcagat
    10141 cgacgacatc ggggacgaac cgctgcccgg cacgaccgac cgggtcgccg ccctcgacgc
    10201 catcgaggcc gagctgcggt cggtgtacgc cggccgcgag gtgagccacc cggtggtgcg
    10261 cggcctcgcc cccaccgtgg ccgagtgccg gctgcccctc gacgcactcg tgcggttgat
    10321 cgaggcgaac cgggtcgacc agcgggtgac ccggtacgcc accttcgacc agctggtcgg
    10381 gtactgcaac ctgtcggcca acccggtcgg cgagctggtc ctgcacgtct tcggccaggt
    10441 ggatgaggcc cggatcgcgc tgtccgaccg gatctgcacg gcgttgcagc tcgtcgaaca
    10501 cctgcaggac gtggccgagg accaccgccg cggtcgggtc tacctgccgg cggaggacct
    10561 ggaccggttc gacgtcaccg aggacgacct cgcccggccg agcgccagcc gccagctccg
    10621 cgagctgatc gagtacgagg cggagcgggc ccgggcgtgg ctcgacgccg gcgcgccgct
    10681 ggtggccgcg ctgcacggtt gggcccggct cgcggtgagc gggtacctgg cgggcggccg
    10741 ggccaccctc gacgcgctgg cggcggccgg ccacgacccg ctgtcggcca ctgtccgtcc
    10801 ccggggccgg cgcgtcctgc accgctggct ggccgccacc gtgaggagcg ccggatgacc
    10861 acgatctgcg acgtcgacac ggcctaccgg cgctgtgagc agataacccg cagccgggcc
    10921 gccaacttcg cgtacgggat ccgactgctg ccgccggtga gacgccgcgc cctgtcggcc
    10981 atctacgcca cggcccggcg gatcgacgac atcggcgacg gcaccatggc accggacgag
    11041 aagctcgacc acctggcgcg tacccgggag gcgctgcacc agctgcccgg caacgacgac
    11101 ggcgacccgg tgctcaccgc gctcgccgac gccgcggtac ggctgccgat tcccctggcg
    11161 gccttcgacg aactcatcga cgggtgcgcc gccgacgtga ccggccggac gtacgccacc
    11221 ttcgatgacc tgcactggta ctgccgctgc gtggccggct cgatcggccg gctctccctc
    11281 ggggtgttcg gcgtcaccga ccgggtccgg gccgagccgc tggccgacgc gctgggcgtg
    11341 gcgctgcaac tgaccaacat cctgcgcgac ctggtggagg accgggccga cgggcggatc
    11401 tacctgccgg ccgaggacct cgaccggttc ggctgcacgc tgcggctgga ggggggccgg
    11461 ttcaccgacc cacccgatcg gctgatcgaa ctcgtccgct tccaggccca gcgggcggcg
    11521 cagtggtacg acaccgggct gcggctgctg ccgctgctgg accggcgcag cgcggcctgc
    11581 accgccgcga tggccggcat ctaccgccgc ctgctcaccc ggatcgcggc ggacccgctg
    11641 gcggtcaccc gcagccgggt gtcgctgccc gtccgggaga aggcgtgggt ggccgcacgc
    11701 gcgctcgtcg gacgcaccac atgaccgccc cgcaggtgcc gggcgggggc ggcagcgtct
    11761 gcgtgatcgg gggcggcctg gccggcatcg ccgccgcgat ccggctcgcc gaccaggggc
    11821 tgccggtgac gctgctggag agccggcccg aactcggggg agcgacgtac tccttccgcc
    11881 gcgacgggct caccgtcgac accggccagc atgtcttcct ccgctgctac cacgcctacc
    11941 gggggctgct cgaccgactc ggcgtcaccg acgacgccca ggtgcaacca cggttcgcgg
    12001 tgccggtgct gctgcccggc cgagccccgc acctgctggc ccgcggccgg ctgccggcac
    12061 cggcgcacct gctgcccgcg ctggccgcgt accggctgct cacccccgcg gaacggctcg
    12121 ccgccgtgcg agccgccgcc gcgctgcgcc acgtcgaccc cgacctgccg gccaccgacg
    12181 cccgcagctt cggcgagtgg ctcgccggcc acggccaggg cgatcgggcc gtacgtcgac
    12241 tgtgggacct ggtcacggtg gcggcgctga acctgcccag cgcgcacgcg tcgctggccc
    12301 tggccgcccg ggtgttccgc accggactgc tcgacgccac cgacgccggc gacatcggcc
    12361 gccccacggt cccgctgacc gagctgcacg ccgtgccggc ccggcggctg ctgcaccagc
    12421 tcggcgcccg ggtgcggacc cggtcccggg tccggtggat ccacccggaa tccgacggat
    12481 tccgggtcgg tctgagcgac ggcgagatcg ccacggacgc cgtcgtcctg gccgtgccgc
    12541 accacgtcgc cgccgcgctg gtgccgccgg ccgccgcgcc cgacgccggc gactggcacc
    12601 ggctcggcgc cgcgccgatc gtcaacgtgc acctgcgcta cgcccgccgg atcaccgagc
    12661 tggccatggc cgccgccgtg gagtccccgg cacagtggat cttcacccgg cccgggtcgg
    12721 acgacgcgca gcacgtggtg gtgtccctgt cggccgccga cacccagatc gaccgacccg
    12781 ccgccgaact ggtggcggtt cagcgcgcgg cgctcgccgc gctctttccc gccgcgcggc
    12841 acaccccggt acgcgacgcg ttcgtcacca gggaaccgcg ggccaccttc cggcaggcac
    12901 ccggcacccg cgcgtaccgg ccggccacga cgacccgcct acccgggctg gtgctggctg
    12961 gcgcatggac cgacacgggc tggccggaca cgatggaggg cgcggtgcgc agcggccagg
    13021 aggccgccga cgtcgtcgcc cgccagctcg cgtcccggcc ccgacaccac acggaggccg
    13081 cacgatgacc atcgcgcaca gcgaccgcac cagccagatc cacattcacg tggagccggc
    13141 catccgggtg ctgctggacc ggctggaccc gggaaaccgg ttggtcgccg gttaccagat
    13201 gggctactgg aacgccgacg ggtcgcccgc tgtccgccgg ggcaaggggc tgcggccggc
    13261 gctggccctg ctctcggccc aggccgccgg ggccgacacc gaggccggcg tgccggccgc
    13321 cgccgcggtc gagctgacgc acaacttctc gctgttgcac gacgacgtca tggacggcga
    13381 cacggagcgt cgccaccggc ccaccgcctg gaccgtgttc ggcgtcagcc gggccatcct
    13441 ggccggggac gccctgatcg ggctcgcgta cgaggccctc gccgaggtca ccggcggcga
    13501 accggcggtg cggcggctcg ccctggacgt gcgggccctg atccgtggac aggccgccga
    13561 cctggccttc gaacaccgcg acgacgtcac gctcgacgag tgcctggcca tggccggcga
    13621 caagacggcc gccctgctgt ccggctcgtg cgcgctcggg gcgctgctct gcggcggccc
    13681 tgccggcctg gtcgacgggc tgtcccggtt cggcttccac ctcggtctgg ccttccagct
    13741 cgtcgacgac ctgctcggca tctggggcga cccccggcgt accggcaagc cggtcggctc
    13801 cgacctgcgg gcccgcaagc gcaccatccc cgtggtgcgg gcggtgaccg acggcggcag
    13861 cgccggccgg gccctggccg agctgtaccg ctcgccggcc ccgctgaccg acgacgacgt
    13921 ggcccgcgcg accggactga tcgaggcgac cggagcccgc gactggacgc ggcagcgggc
    13981 ggcgcgggag accgagcgcg cccgggcgga actcgccgcc ctggacctgc ccgaccacgt
    14041 acgccgcgaa ctcgccgacc tcaccacctt catcaccgga cgggatcact gatgaccgaa
    14101 ctgctctcgc cgaagcccac cgggtccgtc gtcaccgccc cactggccgg cggcgacacc
    14161 acgtccgacg ccgcccggga agccctgcgc cgcgcccgcg accacctgct cgggctgcag
    14221 gacgatgccg gctggtggaa gggagacctg gccaccaacg tcacgatgga cgccgaggat
    14281 ctgctgctgc ggcagttcct gggcatccgt accgccgagc agaccgcgga atccgcccgc
    14341 tggatccgct cccagcagcg accagacggc tcctgggcca ccttccacgg cggccccggg
    14401 gacctgtcca ccaccatcga ggcgtacctg gcgctgcggc tggccggtga cgcgcccgag
    14461 gcgccgcaca tggcgaccgc cgccgcgttc gtccgggacc acggcgggct ggtcgccagc
    14521 cgcgtcttca cccgtttctg gctggccctc ttcggccagt ggccctggtc ccggctgccc
    14581 gccgtgccac ccgagctggt gctgctgccg ccgtggatgc cgttcaacgt ctacgacttc
    14641 gcctgctggg cgcgccagac catcgtcccg ctgtccatcg tccgcgcgct gcgtcccgtg
    14701 cgcgacctcg gcttcaccgt cgacgaactg cgcaccgccg acgcgccacc ccggccaccc
    14761 cggctgctca cccggcccgg cgtgctgcac cgcctggacc ggctcgccgc cggctacgag
    14821 cggatcgccc gcggtccgct gcgccgcaac gcgctgcgcc gggccgccga gtggatcgtg
    14881 gcccgccagg aggccgacgg gtcctggggc gggatccagc cgccctgggt gtactcgctg
    14941 atggcgctgc acctgctcgg ctacccgttg aaccaccccg tcctgcgcag cggcctggcc
    15001 gggctggagc ggttcacggt gcgccagccg agcccggacg gcccgatgcg ctggctggaa
    15061 gcctgccagt cgccggtttg ggacaccgcc ctcgccgtca ccgcgctctc cgacgccggg
    15121 ctgccggccg ggcatcccgc cctggcgcgg gccggcatct ggctgctcag tgaggagatc
    15181 cgggtccgcg gcgactgggc ggtccgccgg ccgcacgtcc ccgccggcgg ctgggccttc
    15241 gagttcgaca acgacgggta cgccgacacc gacgacaccg ccgaggtgat catggcgttg
    15301 cggcgcacca acctgccggc cgacgcggcc gtgctgaggg ccacccgctg gctgctcggc
    15361 atgcagtgcc gcgacggcgg ctgggccgcc ttcgacgccg acaacacccg caaggtgctc
    15421 ggtgacctgc cgttctgcga cttcggcgag gtcatcgacc cgcccagcgc cgacgtgacc
    15481 gcgcacatcg tcgaggcgct ggcggcggag aacttcgccg acacggtgcc ggtgcgccgt
    15541 ggcgtggcct ggctgctgcg ggcgcaggag ccggacggct cctggttcgg tcggtggggg
    15601 gccaaccacg tctacggcac gggcgcggtg gtgccggccc tggtggccgc cggcctgcgg
    15661 cccgggcacc cggcgatccg ccgggccgtc gactggctgc tcgcgcacca gaaccccgac
    15721 ggcggctggg gcgaggacct gcgctcgtac cgggatccgg cctgggtcgg gtgtggcgag
    15781 tccaccgcct cgcagaccgc ctgggcgctg ctcgcgctgc acgccgccgg ccacggccct
    15841 ggcgaggccg ccacccgtgg ggtgcgctgg ctggtcgaca cccagcgccc ggacggcggc
    15901 tgggacgagc cgcagtacac cgggaccggc ttccccggcg acttctacat caactacggc
    15961 ctgtaccggc tggtcttccc gatcagcgcg ctcggccgga tcctggacgc gcgggccacc
    16021 ggcctcgacg ccgaggcgct ggcgtgaccg caccggcggg cagtccgccc tggacgctgt
    16081 acgcgccgat gcgcgcggag gcgtcggcgc tacggcgcgg gctgaccaac cgcgccttcc
    16141 ccggccggcc ggcgctgcgc cgcaccggcg tcgggccgcg gcgcgctcgg gcggccgccg
    16201 cccgccgtcc ggccggcgtc gccccggtcg ccgtcgccgg catcggcggc ggactggcgc
    16261 ccgggctggc cccgggcgac gtcgtggtgg ccagcgaggt acgcgtcgac ccgctggctc
    16321 ccggcgaccc gccgcgggtg ctgcggctgc cggacgctcc cctgctcgcc gccgcgctgc
    16381 gccgccgcgg gttacgggtg cacgtggggc ccgtgctcag caccgaccgg ctggtcgacg
    16441 gtgccgcccg ctcccggctc gccgcgaccg gcgcgctggt cgccgactgc gaatcggcgt
    16501 ggctgctggc cgggcgcggc gaccggccgg cggcctgcgt ccgggtggtc gccgacacct
    16561 cggccgggtc gctgtaccgg ccggccacgc tcggccgggt ccgcaccgcg ctgagggtgc
    16621 tgcccgtcgt ggcgtcggcg ctcgccgagt gggcggcggc gagcagcctg cgacaggtcg
    16681 tgctggcctc gccccgctcg ttctgcgccg gggtggagcg cgcgatcgcg gtggtggaac
    16741 aggctctgcg ccagcacggc ccgccggtct acgtccgcaa gcagatcgtg cacaacgccc
    16801 gggtcgtggc cgatctgcgg gcccgcggcg cggtcttcgt ggacgaactc gacgaggtgc
    16861 cggacggcgg ggtgaccgtc ttctccgccc acggggtggc gccggcggtg cgccgggaag
    16921 ccgcccagcg ccggctaccg gtgatcgacg cgacgtgccc gctggtggcg aaggtgcacg
    16981 ccgaggcgcg ccggttcgcc ggccggggcg acaccgtgct gctgatcggc cacgccggcc
    17041 acgaggagac cgacggcacg ctcggtgagg cgcccggacg gatccgcctg gtgcccgatc
    17101 ccgccgcggc cgagtcggtg cgggtggacg accccgaccg ggtgtcctac ctggtgcaga
    17161 ccaccctcgc gaccgacgag gcggccgggg tcgtcgaggc gctgcgccgc cgcttcccgg
    17221 cactggccgg ccccgactcc gacgacatct gctacgccac caccaaccgc cagcaggcgg
    17281 tcaccgaggt cgccgcccgg gccgaggtcg tcctggtcgt cggctcggac aactcctcga
    17341 actcgcggcg gctggtggag gtggccgaac gggccggcgc ggcggcgtac ctggtcgagg
    17401 acgtgagccg ggtggacctg cgctggctgg ccggcgcggc gacgatcggc gtctccgcgg
    17461 gagcctcggc gccacccggg ctggtcgacg aggtcgtcgc cgcgctcacc gccctcgggg
    17521 cgagggaggt gagcgagcac accacgaccg tcgaggacgt cgctttcacc ctgccgaagg
    17581 aggtacgtca gccgtgagca tgccgttgcg ccagagcctg cggatcgcca gctacctgat
    17641 ggaacagaag atgcgcggcc gcaagcggtt cccgctgctg ctggaactgg agccgctgtt
    17701 cgcctgcaac ctgagttgcg cgggctgcgg caagatccag cagccggcga atctgctcaa
    17761 acgccggatg ccggtggagc aggccctcgc cgccgtggag gagtgcggcg cgccgatggt
    17821 ctccatcgcc ggcggcgaac cgctcatgca cccggagatc gacaccatcg tcgccgagct
    17881 ggtccggcgc aagaagttcg tcttcctgtg caccaacgcc gtcctgctgc ccaagaagat
    17941 cgagaagttc cgcccgtcgc cgtacttcgc cttcaccgtg cacatcgacg ggctgcggga
    18001 gcggcacgac gcggcggtct gcaaggacgg cgtcttcgac gccgcggtcg cggccgtccg
    18061 ggacgccaag cggcgcggct tccgggtcac caccaacacc accttcttca acaccgacac
    18121 cccgcagacc gtgatcgagg tgctcgacta cctcaacgac gacctgcgcg tggacgagat
    18181 gatgctctcc ccggcgtacg cctacgagaa ggcgccggac caggagcact tcctgggcgt
    18241 cacggagacc cacgagctgt tccgcaaggc cttcggcggc ggtcggcgcc gccgttggcg
    18301 gctcaaccac tcgccgctgt tcctggactt cctcgagggg aaggtcgact tcccgtgcac
    18361 cgcctgggcg atcccgtcgt actcgctgct gggctggcag cggccctgct acctgatggc
    18421 cgacggatac gccgccagct accgggagct gctggactcg accgactggg acagctacgg
    18481 ccggggacgc gacgcgcggt gcgccaactg catggcgcac tgcggctacg agccgaccgc
    18541 cgtgctggcc accatgtcct cgctgcggca gtcgctgcgc gcgatgcgca actgagctcc
    18601 gcgcccggct gagcgcgggt caaccgaatc gggccgccag gcgtcggtac accgccggct
    18661 gcagtccccg taccgccacc ggcaggcgca accagcccgg cacgtagacc tcggcccggt
    18721 cgcgggcgat ggcggcggcc agcgcgtcgg ccacccgctc cggcggcagc ggtcggggcc
    18781 ggcggcggcg gtacgcctgc ccccggcggt cgaagaacgg cgtgtccacg accccgggga
    18841 cgaccacgct gacggtgatc cggtgcgggg ccagctccag ccgcaggctc tgcgcgaaga
    18901 tgtccaggcc cgccttgctg gccgcgtaga ccgcctcccc gcccaccccc agccggccgg
    18961 cgatcgagcc cacgaaggcc aggtgcccgc cggggcggcg catcccgggc agcagcgccc
    19021 gggtcagctc gatcggcgcg tgcaggttca ccgcgagcag ctcgtcggtg accgcgtccg
    19081 gcatctcggt gaaccgcccc gcccagccga cgccggcgtt gttgaccagc acgtccaccc
    19141 gtgggtgccg ggcgaggacc cgctcggcca gctcccgtcc ggcgccgggc cgggccaggt
    19201 cggccggcag cgcggcggcg ccggtctcgg cggcgagccg ggcgaggcgt cccgggtgcc
    19261 ggccgacggc caccacctgg ctgcccgcac gggcgagccg ccgcaccacc gccgccccga
    19321 tgcccgagga cgcgccggtg accaggacca ccgcgccggt caggcgcacc gcggcacccc
    19381 cgaccgcgac cgtccggccg gtgcgccctc cggcacccgc tccaccgacc cgccgccggg
    19441 cccggccccg ccttcgtcgc cggcctcgac ctcgtcaagc agctcggtca ggctggtacg
    19501 cagggcggcg acgaacgcgg tgccgatgtc ggccagcgac tcgtccagca gcacgccgat
    19561 ctcgaaggcg ttgcggcacc gcagcacccc gacgccgagg ggcacgccct cggccagggc
    19621 caccaccggg atcgccgccc ggagcggggc gccggccagc agccgggagt cccagggcag
    19681 cgccatgtag gacacgatga cgttgagatg ccggctggtg tacacccgtc gggccagcgc
    19741 ggcgtgcagc ggcgcgggta gcgcacccat ggtccgcatg accaggccgg ccgcctcggc
    19801 ttccccgctg tccaacgcgg tgcgcagcga ctgtcgtacg gcgaccaccc ggtcctgcgg
    19861 cgagcagcgc cccagcggca ggtccaggtt caccgccccg gtccagttgc cgtgggtggg
    19921 ggcccgccgt cgcgggttcc gggagaccgc gaacatcgcc cgcagccggg gcggcgcgcc
    19981 ggccggccgg acggcgccca gcgccgtggc ggtgagcgcg agcatcagtt cactggcgtg
    20041 cgcccggcag gcgcgggccg cgcggagcac ctcggcggcc ggcaggctcg cggtgaccag
    20101 ccggcgctcc ggcgagccga tcgggcggtt gaagccggtg accggcgccg gtccctgggt
    20161 ggccagccgg gccaggccgc gcgcggtgag cccgagccgg cggagccgct cgccccgctc
    20221 gggccgggcg accgtggcct gctccggcgt gaacggcgcc gggcgttgcg ggccggccgc
    20281 ccggccggcg gggcgatcga gtagccggcc caggatgccg atcacggaca tcccgtcgcc
    20341 caggctgtgg tggaccttga ccgccacccg ggtacgccgg tccggcaggc cgctgaccag
    20401 caggatccgc cagagcgggc ggtcggcggc cagcggttcg gaccagaacc gatccagggc
    20461 ggcgccgccg tcgtcgccgg gggcgaccgt gacctcgtcg acgtgggcgg cggggtcgac
    20521 gtaccggtcg acgatccagc cggggcggcg ccaccggccc cggttgtcca ggcggcggcg
    20581 cagcgtggcg atggcgggca gccgcgcggc cagcagcgcg accagatccg cggcggcgac
    20641 tgcccggccg tcggctcggg ggccgagttc cagcactgtg ccgatgtgct gggccacccg
    20701 ctccgactgc acgtgcagga agaacgcgtc ctgggggcgc agcggccagc tggccggccg
    20761 gccgacgggc ggcagccggt ccatgcccgg ccggccggcg accgacgccg gccgggtgtc
    20821 gccgacgggc ccccgcgcgt cggcgagcgc aggcagcccg aggtccggca ggtgcgggtg
    20881 ggcggcgggg gcggtcgcgc cggcggcctg tccgccgacg agccggctgc ggacgcaggc
    20941 gaccagggcg ttcgggctgt gggccgtctc ggccacgccg gcggcggtca tcagcgccgc
    21001 gttggccacg ccgtgcgccg cgatgggccg gtacatcacg atgggggtgc cgctggccca
    21061 ggcctccagc gccgtggccc cgcccgcgtt cgtgaccacc agcccggcgg cccgcagcag
    21121 cgtgggcatg tcgtcgaccc actgccggac cagcagccgg tcggggggca ggcgcagtgc
    21181 ggccagccgc tcgaccagcc gctcgttgcg tccgcagacg gcgaccacct ggaccgggtc
    21241 accgatgccg accagcgcgt cgatggcctc ctcgacgtgc ccgaagccgt acgagccgca
    21301 ggccacgacc actgcggacc gggcgggatc gagaccgctg cgccgggcgg cctcgacccg
    21361 gtcgccgggg tggaaccggt cgagcaccgg tggcgcgcac acccccagcc gtacgccggg
    21421 cgcggcgacc gcggccaccg ggacggccgc cggatggacc accaggtcca gatccagctc
    21481 cgagtagacc caggacgggt gcggcgcgaa gtcgcagacc cacgccccga ccggtacgcc
    21541 caggccacga cgccggcgca gccaggcgag gccggcgctg cccagcggat aggtggagac
    21601 gatcaggtcc gggtcgaacg cctcgacgac cggggcgagc cggcggccgg cccaggctcc
    21661 ggtgaaccac ttggaggcgg tggcgaacca ccggtgccgc cagatcgacg cccagaagaa
    21721 ctcgtacagc cacggcgtcg cggcgacgtt ggtgcggtag gtacgccgga acgagcggcc
    21781 gacccccggg cccatcacgt cgagagtgtc gacccagccc acccggctgc cgggccagag
    21841 cgtgcggacc cgttcggcca gggcgcggcc ggtggcgtcg tgcccgccgc cgatgtcggc
    21901 cgagacgacc agcacccgcc gggcgaacgg ctcggtgccg ccctctggcg tcgccggact
    21961 gggggcctcg gcgccgcccg tggcggtcga ctgtcggacg gccaggggct gcgcggggcg
    22021 catggtcgct gacatgtcgg ctgctcccag gcaatgcgcg gagaggggtg ccagaagtca
    22081 cccctcgtag gcgttcatca gcttaacggc tgctttgccc agatatgcga tatcttcgaa
    22141 caccgggcgc ccgtcgggcg acaggtgtgc cgggggagag gccatggcga cgggaagacc
    22201 ggagacgggg cgaggccgac cccgtccgct cggcgtaccc gtgctggcgc cggtcccggg
    22261 cggctggtgg ttcgacgggc tgctggtcgc cgcgttcgcc gcgctcaccg cggcgctggt
    22321 ctggtggtcg ccgctgctgc gcctggacct cgcggtgcga gactggtgcg acgcccaccg
    22381 cccgagcccg gtgcacgtgc tgatgcaggc cttcgactac ctgggccagg gcggcgggct
    22441 gatcgtcgtc accatgctgg tggccggctg gctggcctgg cagcaccgga cggcgcgccc
    22501 catcgtcctg gccgggctgg ccccgatcat cagtaccctg ctgatcgtcg gcctgaaacg
    22561 ctggacctcg cgcggcgcac cacaccacgg ctcggtccgc ctgttcaccc acggcccgga
    22621 ggtggagtac ccgtccgggc acgtgagcaa cgccatcgtc tactacgtgg tgctggcggt
    22681 gctgctcgcg ccgtacctgg ccgtgccggc gcggcggatc gtgcagtggc tgcccggcgt
    22741 gctgaccttc atcggtacca cctatgtgag ctaccactgg ctcaccgaca gcatgggcgg
    22801 atacctgctc gggctgctga tcgcgcggct gctcctgcgg gtgccgtggc gcaccgtgcc
    22861 acttccgcgc tggctggacc gggcgagcgc gtgctgagcg aggtagcgcg gctggcggcg
    22921 ggcgccccgc tggcgctcgt cgccgccgca gcattcggcg cgtcctcgtt gttgcagttc
    22981 cgggcctccc ggcaggtgcc cgaggagcgg gccgggcggc cccggctgct gatccggctg
    23041 atccgcctcc gcggctggcg ctggtcggca gtgctcgcgg cgatggcgtt cgcctgccag
    23101 gtcgcggcgt tgagcctggt gccgctgatc ctggtgcagc cgctgctggt gaccggcctg
    23161 gtgtggtacg tcctgttgtt cgccggggcc cagcaccgcc gaccggatcc gcgcatcctg
    23221 ctggaatcgg ggctgtgcct gctcgggctc ggcgccttcc tggcgttcgc gcgaccgacc
    23281 catcagcagg ggcgagggct cgactcgttc gggtcggccg cgctgctcgg cgtcgcggtg
    23341 atcctcggcg tgggcctgtg cctggtgggc gccctcaagc tgggccgcaa gtggcgcccg
    23401 ctgccgctgg ccgtcgcggc cggcatctgc tacggcgtga cggccgggct gatcagcagc
    23461 ctgggcctgc agtccgaacc cagctcactg gcggtgttcg gccagtggca gacgtacgcc
    23521 atcgccgtgc tcggcccgtt cggcgtgctg ctgagtcaga acgcctacca ggccggcccg
    23581 atgggcgcac cagccctggc cacgatcacc gtcaccgacc cgttggtgtc catcgcggtc
    23641 gggttgctct ggctggacga gcggatccgc accggcacct gggtcgtgct gggcgaggtg
    23701 ctcgcggtgc tggtggtggt cgtcgcggtc tccctcctcg cccggcgggc accccacgtc
    23761 gccggtgcct gagtggcgcc gtccgccgcc cccgacgggc ccgcggcacc gtcaccgccc
    23821 caggtgtgcg gccggccgcc aggggtaccc gggctgccgg accaggggag gcgccgatga
    23881 cgaacgaagc accggactac ttccggccgg agcatggcat ggtgctcacc cacctgctga
    23941 tcgtgcggga cgtggaccgc tcccgcgagt tctaccgcca ggtgttgggc gccaccgtga
    24001 tccgcgaacg cgagccggcg atcctccgct tccacaacgg ctacctggtg atcaacaacg
    24061 agggcggccc caccgacgac aagcccaccg tacgggccca ggcgccggcg gacccggact
    24121 cgctcagttg cgcgctgaac atccgggtca ccgacgtgcg ggccgtctac gagcagtggc
    24181 gctcccgcgg tgggcagttc ctgaccgagc cgaaggacca cggggtcgaa atccgctgct
    24241 acctgcgcga tccggacggc tacctgatcg aactcggtca ggcgacgggc attctcgccc
    24301 aactgtcggg tacgcccgcc ggctgagctg ccccggcgct gccgagcggc tgccgagccg
    24361 cggttgagct gtcccggcgc tggcgagccg cggttgagct atcccggcac cgccgagccg
    24421 cgggtgagca ggtcggccac ggccgaggcg gtctccgggt gccgggtgag cagcgtcgcc
    24481 ggaccggcgt gggcggccgg gccctcgggt cgccacccgc cggcacaacc gagcagccgg
    24541 gcgaccgcgt cgatcgactc gggatgctcg gtgagcagcc ggacgaccga cgccgcggga
    24601 gcggccggcg gtgccggtgc cgcggcgggc gccacccagg gcggcaccca ggcgtccacc
    24661 tccgacaggg tgccggggaa ggtgcgagcc gcctcgcgga tcagcaccgg gaccagctcc
    24721 ggcccgtgct cgcgcagggt ggtgatgagg gtcggcagcc agggcagcag gatcgggtcg
    24781 ggcagctggg cgaacgcggt cgacatcagc tccaccacga acggcgccag ccccggcacc
    24841 gattccaggg cctgcacgaa gccggacaga tactgcggga cggtcgggac caccagcggg
    24901 ttcgccagca gatcggcgca gcgggcacgc agctcggcga gggggagcag cccgaggtgg
    24961 tgccgggccg cccagagcag ggcggtcttg gcgggcgtct cgggatggga ctgggcgacg
    25021 gccagttcga gctgggcccg gtcgcagccc agcgacaggg ccaggccctc catgccgaac
    25081 aggaagccga gcatggcgcc gacctgccgg acgccggcct gctcgtcgac gaaggcggtc
    25141 ggcagcagcg tgcagtagtg cgcgtacccg gtggtcacga acgcctcgcc ccagccgggc
    25201 agggccggcg cggtggcccg atagtgggcc agcagccggc ggatccggcg cagcacgcgc
    25261 ggggcgtcgt cgacgtcgcg ctcggcggcg agcagctcca ccgcccgggt gccgagctcg
    25321 tcgaccagcc gagggctgcc cagcagacgg atggcgtccg ccacggcggc gagggcaccg
    25381 gcggcggtcg cctccgggcc gcggaccgcc cggcgcagcc gctgctcgag cacctgctcc
    25441 accgtgacac cctcgtagcc gagctcgatc aacgcgcgct ggttgcggcc gagggcgagg
    25501 tcccagctct cctggagcga ccggtgcccc agccgccgct cgcccatgat cggacggacc
    25561 gcgtcgggtg gcagcaggtg ccgcagcagc cagagcaggt ccgagcaggg tgccagccgg
    25621 ggctcggccc gcagatccag cagggcccgt tgcaccgtac gccgctccag gtccaggccg
    25681 agcggctgaa gccggtcgag gacgtcgcgg gccagcggcg gcagggcgtc gtagccgacc
    25741 tggccgaccc ggtctccgcc gagcaggatc tcgcagagcc gccggacgtc gcgccggccg
    25801 ggtacgacat ccttctcgat gcaggtgacc gccgcgtcgg cgaagtcgta cggggtgggc
    25861 cgggcccggt tgcgcagccc ggcgaggagg atcgaggtct cgaagacggc gatcgcgtcg
    25921 gcggtgctgg ccaggtagcc gttgcggcgg gcgagccgga cgatgtcgac gcaccagccg
    25981 cgcagctccg cctcgtcgag gccgccgagc tccggtggcg cggcgaggaa cccggagagc
    26041 cggtcgg
//
