LOCUS       NZ_LT607411            24763 bp    DNA     circular CON 11-DEC-2024
DEFINITION  Micromonospora viridifaciens strain DSM 43909 chromosome I.
ACCESSION   NZ_LT607411
VERSION     NZ_LT607411.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora viridifaciens
  ORGANISM  Micromonospora viridifaciens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091545.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:27:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,508
            CDSs (total)                      :: 6,445
            Genes (coding)                    :: 6,270
            CDSs (with protein)               :: 6,270
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 175
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 83 of 175
            Pseudo Genes (incomplete)         :: 110 of 175
            Pseudo Genes (internal stop)      :: 8 of 175
            Pseudo Genes (multiple problems)  :: 25 of 175
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:55:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2270134
            Orig. end                         :: 2294897
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607411.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24763
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="terpene"
                     /region_number="7"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24763
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10861
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10861
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5861](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5861)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            109..876
                     /locus_tag="GA0074695_RS10775"
                     /old_locus_tag="GA0074695_2193"
     CDS             109..876
                     /NRPS_PKS="Domain: ECH (13-243). E-value: 6.4e-45. Score:
                     145.3. Matches aSDomain:
                     nrpspksdomains_GA0074695_RS10775_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018722897.1"
                     /locus_tag="GA0074695_RS10775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2193"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_089006144.1"
                     /transl_table=11
                     /translation="MTSATTGVRLDCDGPVATVTLCRPDVLNAQAPAMWRAMSDFSREL
                     PGDVRVVVVRGEGRAFSAGLDLSVAGASGPGSFAELATLPEQECADRIAEYQAAFTWLH
                     RPDVISVAAVQGYAIGAGFQLALACDLRVLAEDAKLSMAEVTLGLVPDLAGTKRLVELV
                     GYSRALEICATGRRMDAAEADRIGLATLVVPPAELDAAVRDLTAGLLANSRDAIVEIKA
                     LLAGAAGRTHADQQRAEREAQTRRLRDLAGRGE"
     aSDomain        148..837
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074695_RS10775_ECH.1"
                     /evalue="6.40E-45"
                     /label="GA0074695_RS10775_ECH.1"
                     /locus_tag="GA0074695_RS10775"
                     /protein_end="243"
                     /protein_start="13"
                     /score="145.3"
                     /tool="antismash"
                     /translation="GPVATVTLCRPDVLNAQAPAMWRAMSDFSRELPGDVRVVVVRGEG
                     RAFSAGLDLSVAGASGPGSFAELATLPEQECADRIAEYQAAFTWLHRPDVISVAAVQGY
                     AIGAGFQLALACDLRVLAEDAKLSMAEVTLGLVPDLAGTKRLVELVGYSRALEICATGR
                     RMDAAEADRIGLATLVVPPAELDAAVRDLTAGLLANSRDAIVEIKALLAGAAGRTHADQ
                     QRAEREAQ"
     misc_feature    complement(935..950)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.42"
                     /tool="antismash"
     gene            991..2973
                     /locus_tag="GA0074695_RS10780"
                     /old_locus_tag="GA0074695_2194"
     CDS             991..2973
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019030577.1"
                     /locus_tag="GA0074695_RS10780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2194"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_089009899.1"
                     /transl_table=11
                     /translation="MAGGGMGGWSMLRSMRDRDQVSAHQLKRGTAKRIVAFARPYRRDI
                     VIFLLTVVVAAVIGVATPLLAGDVIDAIAGRRPDAGSTVVRLALIIAVLAVADALFSLA
                     QRWYSARIGEGIILDLRTRVYDHVQRMPLQFFTRTQTGALVSRLNNDVLGAQRAFTSTL
                     SGVVSNVIQLVLTAGAMLVLSWQITALALVLLPIFIIPARRVGRRLAEITRESYNLDAK
                     MNATMTERFGVAGALLVKLFGSPEVEARRFARRAERVRDIGIQSAMYSRTFFVAMLLVA
                     SLAQALTYGLGGWLAVAGAVSAGTVVKLALLLTRLYGPLTALSNVRVDVMSALVSFDRV
                     FEVLDLRPGIEEKPDAVPLPRGSGRVEFRDVRFRYPSAAEVSLASLEEVAALDRTVNEP
                     VLKGVSFTVEPGQMVALVGPSGAGKSTLSMLISRIYDATDGQVLVGGVDVRDATLASLR
                     DEIGVVTQDSHLFHETIRENLRYAKPDATDDEIWAALAGAQVADLVRALPDGLDTMVGE
                     RGYRFSGGEKQRIAIARLLLKAPSIVILDEATAHLDSESEAAVQRALSVALTGRTALVI
                     AHRLSTVRDADQILVLDEGRIVERGRHEELVAVGGLYAELYRTQFAVADSPTPYAEPEQ
                     PQPVVSTVPLGTYVAQEALPPATAN"
     cand_cluster    2230..24763
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2230..24763
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[12229:14763](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12230..14763
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            complement(2970..3533)
                     /gene="mug"
                     /locus_tag="GA0074695_RS10785"
                     /old_locus_tag="GA0074695_2195"
     CDS             complement(2970..3533)
                     /EC_number="3.2.2.28"
                     /GO_function="GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /gene="mug"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287431.1"
                     /locus_tag="GA0074695_RS10785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2195"
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="WP_089006145.1"
                     /transl_table=11
                     /translation="MNATRRYPRPTKEQLAAAVDKLLPDVIAPGLDVLFVGINPGLWSA
                     ATGWHFARPGNRFWPALHRGGFTPRQLHPSEQDELLTLGLGSTNMVARATARADELTAA
                     ELVAGAAELTGKVERYRPRWVAVVGVTAYRIGFARPKAGFGPQPEPLGGARLWVLPNPS
                     GLNAHFTPETLGAAFAELRAAVSA"
     gene            complement(3530..4291)
                     /locus_tag="GA0074695_RS10790"
                     /old_locus_tag="GA0074695_2196"
     CDS             complement(3530..4291)
                     /NRPS_PKS="Domain: PKS_KR (8-151). E-value: 6.1e-09. Score:
                     28.0. Matches aSDomain:
                     nrpspksdomains_GA0074695_RS10790_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815297.1"
                     /locus_tag="GA0074695_RS10790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2196"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_089006146.1"
                     /transl_table=11
                     /translation="MDLGLADRVYVLTGASRGLGFATAEQLVADGARVVISSRQPEQVA
                     AAVAALGGPERAIGLTADLTDPGTPERLVAAAREQFGRLDGALISVGGPPRGTAAQTTD
                     EQWRASFETVFLGSVRATRTVAAALSSGGAIGLVLSTSARAPLPGLGISNGLRPGLAGV
                     AKDIADEYGPRGVRVFSLLPGSIMTDRNRELLAASGDPERTRAQAEAGIPLRRFGEPGE
                     FGRVAAFLLSPAAGYVTGVTVPVDGGVLRGL"
     aSDomain        complement(3839..4267)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074695_RS10790_PKS_KR.1"
                     /evalue="6.10E-09"
                     /label="GA0074695_RS10790_PKS_KR.1"
                     /locus_tag="GA0074695_RS10790"
                     /protein_end="151"
                     /protein_start="8"
                     /score="28.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VYVLTGASRGLGFATAEQLVADGARVVISSRQPEQVAAAVAALGG
                     PERAIGLTADLTDPGTPERLVAAAREQFGRLDGALISVGGPPRGTAAQTTDEQWRASFE
                     TVFLGSVRATRTVAAALSSGGAIGLVLSTSARAPLPGLG"
     CDS_motif       complement(4175..4267)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074695_RS10790_0001"
                     /evalue="1.90E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="GA0074695_RS10790"
                     /protein_end="39"
                     /protein_start="8"
                     /score="26.9"
                     /tool="antismash"
                     /translation="VYVLTGASRGLGFATAEQLVADGARVVISSR"
     gene            complement(4336..4770)
                     /locus_tag="GA0074695_RS10795"
                     /old_locus_tag="GA0074695_2197"
     CDS             complement(4336..4770)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462659.1"
                     /locus_tag="GA0074695_RS10795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2197"
                     /product="hypothetical protein"
                     /protein_id="WP_089009900.1"
                     /transl_table=11
                     /translation="MAARQAELVAALVAGAPVPPGFAAAPLEAARRALLRKRAGEVARH
                     WPLLAAGLGTAWPATFTEWAAGRPGNGSLRDGWDLARALRDHGTLPPLGAEELATREAA
                     ARYDGRNPPRPRRLPAVARAGGAVAVQLAGRVRLLRPARR"
     gene            complement(5001..5861)
                     /locus_tag="GA0074695_RS10800"
                     /old_locus_tag="GA0074695_2198"
     CDS             complement(5001..5861)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018223394.1"
                     /locus_tag="GA0074695_RS10800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2198"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_089009901.1"
                     /sec_met_domain="DUF692 (E-value: 1.1e-77, bitscore: 259.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPTPTGATTSPPSPGPHGVGIGWRSEIAGFVAGLPGLCFVEVV
                     AETLTPAGPLPHGLAELRERGVTVVPHGVRLSLGGAEPVDPARVAHLAGVAAALDAPLV
                     SEHIAFVRAGGLEAGHLLPLPRSREAVAAVVANVRRAQAELPVPLALEPIAALFDWPDD
                     ELDEAAFLTEILDATGALLLLDLANVHANARNRGGDPRALLDRLPLDRIAYAHVAGGAE
                     QGGFYHDTHTDPVPAEVLDLVRELCARRRPPALLLERDGHYPPAAELRAELDALAAASG
                     FPAVT"
     gene            complement(5858..6763)
                     /locus_tag="GA0074695_RS10805"
                     /old_locus_tag="GA0074695_2199"
     CDS             complement(5858..6763)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462655.1"
                     /locus_tag="GA0074695_RS10805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2199"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_089006147.1"
                     /transl_table=11
                     /translation="MTVLASSDDTWGIPGPTFLAIYLTAAAVILLVCGVHRYLVLRGRT
                     PKEPLDAESAAYLSGGAQLAIWTALAAMRRAGVVGVRARGRLAATGYTSTGMTSLQRAL
                     HRAAARGARTGDLRGDQRVADALAGLRDSLEQRGLLVGRGERQFARAGVLALSVLLVVG
                     LVRIVAGLSAGRPTGYLILTVLALVLLLIALWRLPNRTRAGRVALRGLRAKHQYLSPAA
                     RPAYTTYGSAEAAMGVALFGTASLWALDAEFAQQAQAKYQAAASSGSSSGYSCSSGGGG
                     SSCSSGDSGGSSCGGGGCGG"
     misc_feature    complement(6791..6807)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.71"
                     /tool="antismash"
     misc_feature    6824..6838
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(6845..6859)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            complement(6886..7458)
                     /locus_tag="GA0074695_RS10810"
                     /old_locus_tag="GA0074695_2200"
     CDS             complement(6886..7458)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788252.1"
                     /locus_tag="GA0074695_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2200"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_089006148.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILAAARACFARHGYEGATVRRLEEATRLSR
                     GAIFHHFRDKESLFLAVAEDDASAMVETVARNGLVQVMRDLLARALSPDTTGWLGSQLE
                     VSRRLRTDPAFAKRWAERSAAIAEATRERLVRQRDAGVLRDDVPIDVLAQFLELAYDGL
                     VLHLTMGRPAGDLGRVLDLVEEAVRRH"
     gene            7562..8416
                     /locus_tag="GA0074695_RS10815"
                     /old_locus_tag="GA0074695_2201"
     CDS             7562..8416
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462651.1"
                     /locus_tag="GA0074695_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2201"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_089009902.1"
                     /transl_table=11
                     /translation="MSQAVPLPAHPLTVAAVQAEPVPGDVAGNAATAARLVGRAAGARI
                     VVLPELFLPSYHPPTLAADPAGTDVAADEVGGVADPRLDPLRGVARDGGTTVVVGAAVR
                     HPDGRRTISALVVDPTGAVRAAYDKQQLWSGERELFDPGRRGATLLVDDWRFGLGICYD
                     GCFPEHGRAAADDGAHGYLCPSGYLAGSEHRRDLYYAARALDNTMYVVFANVVDGADPW
                     RFNGGAAVYDPEGRPLARGANTGEDVLVATLDPTALAATRAAHTMLADRPADPGLPRAA
                     LPA"
     gene            8472..9116
                     /locus_tag="GA0074695_RS10820"
                     /old_locus_tag="GA0074695_2202"
     CDS             8472..9116
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287424.1"
                     /locus_tag="GA0074695_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2202"
                     /product="HAD family hydrolase"
                     /protein_id="WP_089006149.1"
                     /sec_met_domain="HAD_2 (E-value: 1.7e-11, bitscore: 43.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRDGPFRAWGARFLDGIGAPPADIDWLLSVDA
                     DGLAERWDVADAIRDRYQLGVRAVDLVEELHDGVVAETRLSPLVACALRIADGAGWVPV
                     VVTNGVVRQQEAKIRRTGLDRHVADWVISEEAGVSKPNPRIFALAAQRARMPLRGAWVI
                     GDSPEADIGGATAAGLPSVWLHRGRRWSDSRFAPTRSADGLIAAVAAALAG"
     misc_feature    8516..8530
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            9314..10243
                     /locus_tag="GA0074695_RS10825"
                     /old_locus_tag="GA0074695_2203"
     CDS             9314..10243
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583044.1"
                     /locus_tag="GA0074695_RS10825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2203"
                     /product="serine protein kinase RIO"
                     /protein_id="WP_089006150.1"
                     /transl_table=11
                     /translation="MRDHDFPAPQRRGRGKSRFDDDEPYFLKRGRHPEPVLAEPDDEPD
                     LEDRWSSWDEAVHGPEPHPGWLVTELAARDTELGVLKTGKEADVHLVRRAVPGTDRSCL
                     LAAKRYRDAQHRLFHRDAGYLEGRRVRRSRENRAMAGRTAFGRQMIAGQWAAAEFAALA
                     RLWEIGAASGRIAVPYPVQLLGTELMLEFVGDAEEGQAAPRLAQLRPDAAELRDLWEQL
                     VDALVVLARAGYAHGDLSPYNLLVHRGRLVMIDLPQVVDVVANPQGPDFLARDVRVVGT
                     WFAARGLPVGDADPAELTGRLLREAGLR"
     gene            complement(10353..10601)
                     /locus_tag="GA0074695_RS10830"
                     /old_locus_tag="GA0074695_2204"
     CDS             complement(10353..10601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287422.1"
                     /locus_tag="GA0074695_RS10830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2204"
                     /product="DUF2630 family protein"
                     /protein_id="WP_089006151.1"
                     /transl_table=11
                     /translation="MDDKTILNRISELVDEEHRLRAAAQENEAGTDDAARERLRALEES
                     LDQCWDLLRRRRAARQAHGDPDAQGERPLSEVERYLQ"
     misc_feature    10728..10742
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.32"
                     /tool="antismash"
     misc_feature    10804..10817
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.63"
                     /tool="antismash"
     gene            10896..12233
                     /locus_tag="GA0074695_RS10835"
                     /old_locus_tag="GA0074695_2205"
     CDS             10896..12233
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734913.1"
                     /locus_tag="GA0074695_RS10835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2205"
                     /product="cytochrome P450"
                     /protein_id="WP_089006152.1"
                     /sec_met_domain="p450 (E-value: 3.1e-66, bitscore: 222.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRHVVPSLLGDPAQGLVSFGERSGGEVVRLNLGSFRPFLVTHP
                     EHLQRVLRERADNYVRAGDGLQWRPLKRLFGDGILSDGHYWTDSRHILQPLFTARRIDS
                     LVDRLAEEIDETVAELDGPAADGRPVDMGVEQARIVCQAIMRVFFADKVSVPQAMRIME
                     AQDAIASSVMPRIAVPWAPLAMPMPGDRKFRRALQTINDTLLPIVRAARETAETDGDDI
                     ISTLWRSRTPDGRRLEEWQVRNDTVAMVATTTETTISALTWLWPHLEADPQVAERLREE
                     LDRVVGDAPVRRVHLKDLRYTRQVLDELLRLYPVGWLFPRRAVEEDVLGGVRIPAGSTL
                     VVSPLITHRMSMFWDRPEVFDPDRFAPERVRTRHRYAHFPFGGGPHQCLGMHLFYLEAL
                     LIVATVLSRYRFRLRRPQLPGIKVAAALRPRNRVEVTLERVRGVAG"
     gene            12230..13138
                     /locus_tag="GA0074695_RS10840"
                     /old_locus_tag="GA0074695_2206"
     CDS             12230..13138
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287420.1"
                     /locus_tag="GA0074695_RS10840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2206"
                     /product="terpene synthase family protein"
                     /protein_id="WP_089006153.1"
                     /sec_met_domain="T1TS (E-value: 3.8e-11, bitscore: 41.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVANAVDDQMRNAAEQGRIWALAARGQRDLAEVAGAYPELFPAR
                     PFDAALFSNVASAIAFGAPWCDAARLRITNRAVLWGFALDWLVDYVATSREEIDQISAR
                     CLAVADGGTPAPDDPLGGFLAELRDELATAPAFAEARPLWRGELRKVLDAMAREWDWKH
                     RPTMDGGPAPLPSFTEYLDNADNLACTLVNVAHWIYSGDPATLANLEQLIEASAEVQRI
                     LRLVNDLGTYERDLRWGDLNALMLVEDRSEVQRRIDELVGRARGLLAPLRSSCPEQADY
                     LARQIGFSSGFYRSADFWGAL"
     gene            13135..14763
                     /locus_tag="GA0074695_RS10845"
                     /old_locus_tag="GA0074695_2207"
     CDS             13135..14763
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019033658.1"
                     /locus_tag="GA0074695_RS10845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2207"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_231935109.1"
                     /sec_met_domain="T2TS (E-value: 6.4e-78, bitscore: 261.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAHAASPDDVDPDERSVDGLVAAMGRDPAGRLSPSVYETGRLV
                     ALAPWLTGHASRLRHLLDRQRPDGGWGAPEGYALVPTLSAVDALLTTLTAATPVEVPRD
                     DLRAAAVRGLATLAGWLGAGQRITVPDTPAVDLIVPALVDAVNAHLRRDADLLPGAAPL
                     LLPAGMDRRRADAVRGLVASGRPVPQKLLHALEVLGPAARRRADVRPLTGAVGASPAAT
                     AAWVGDPGQGADPAALTYLDTAVGRLDGPVPCCTPIAVFERSWVLANLARAGVPADPAP
                     DLVAALAASLGPDGTATGPGLPADADTTSVTLYALARAGHPVDPGSLSRYDLGSHFCTW
                     QGEDGSSVTTNAHVLEALGWHAAHRTVHGDAAARRLPALAGWLREQQQADGRWSDRWHA
                     SPYYATSCAVLALNRYASAAVAATPVGRAVDWVVDTQRADGSWGRWAGTREETAYALHV
                     LLGIGPTARPGVPAAARRGVAYLAATADQRDDPPLWHDKDLYAPVRIVRAAIAAARHLA
                     AARPELTGVDGGRSPRGATFMIRNA"
     misc_feature    14805..14817
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            14865..17348
                     /locus_tag="GA0074695_RS10850"
                     /old_locus_tag="GA0074695_2208"
     CDS             14865..17348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788259.1"
                     /locus_tag="GA0074695_RS10850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2208"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_089006154.1"
                     /transl_table=11
                     /translation="MRFRSSNLRTKVVALLASLVALWAFTAWVTVRDGVNLVGVQALDS
                     KVFDPTEPLLLQLQLERRTSLTFLGSPGEEQRSQLAEIRQRTDQLAQEFEESVDNWQVG
                     LLGSDTLDQRIDELIRGLEDLPATRAAVDDKSIERAAAGAAFTGVIEAIYRVYDALGKL
                     DDEQAAEDTAALIGLNRARELLSQEDALLAGALAAGRITPAEQAQFAQVVGARRFTAEQ
                     AITRLPAADQHRYEQMLAGPTFVKLTDLETKVMQGGGTRPPLSAAAWDRAASPALNEIG
                     QVVLAGGDDIVDRAVPIAIWVILRLVLAAGLGLLAVIASIVVSITTARALVQQLERLRE
                     AAFRLANERLPGVVERLGRGEEVDVAREAPPLEFGDDEIGQVGKAFNVVQETAVRTAVE
                     QAELRRNVREVFLSLARRTQALVHRQLTLLDAMERREHDAEELEDLFRVDHLATRMRRN
                     AENLIVLSGSTPGRSWRRNVPMVDVIRGAVAEVEDYTRVNVLPIGPVSLTGRAVGDIIH
                     LLAELIENGLSFSPPHTAVEVRGQLVANGFAIEIEDRGLGMSEEELAAANHRIVDRSEL
                     NLANATRLGLYVVSRLTERHGVKVQLKESAYGGTTAVVMIPLELVTVDEPDASTSGGFR
                     AGAGTAPAGNEPAAAGAPEGRPAGATLELPTVPVAVAETTSAPQPGDEPVGAAEPPATP
                     VGAEAPALTPSGLPARTRRRQPTAEGPGAPAGLPTADTSAEGTGAAGDAPARTHVGLPV
                     RVRQASLVPELRQEPSTPDTDQDEDEAVRPPEQVRRMMSSYQSGTRRGRTDAARLLGGA
                     HGAGDGPDSGDGQTI"
     misc_feature    14880..14895
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.13"
                     /tool="antismash"
     gene            17418..17843
                     /locus_tag="GA0074695_RS10855"
                     /old_locus_tag="GA0074695_2209"
     CDS             17418..17843
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788260.1"
                     /locus_tag="GA0074695_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2209"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_089006155.1"
                     /transl_table=11
                     /translation="MGQKTASSADLTWLLDDLVGRVKQAEHAVALSTDGLLMASSQGLS
                     RDDGEHLAAMAAGIQSLARGAGKRFGGGQVQQTIIEMQSSFLFVTAAGRNACLAVLASE
                     DADVGLIAYEMAMLVTRVGRFVASPTRETAIGENPAR"
     gene            17840..18229
                     /locus_tag="GA0074695_RS10860"
                     /old_locus_tag="GA0074695_2210"
     CDS             17840..18229
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287416.1"
                     /locus_tag="GA0074695_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2210"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_089006156.1"
                     /transl_table=11
                     /translation="MTGQAESAEQEWVDDHAGPVVRPYAVTGGRARPVTGTFDLISLVT
                     ATRADVSAESGLGPEHLAIVGLCQRMQSVAEIAAHLDLPVGTVRVLLGDLVARHLVQVR
                     EPRATPAGLPDDSVFEAVINGLRAL"
     gene            18210..18818
                     /locus_tag="GA0074695_RS10865"
                     /old_locus_tag="GA0074695_2211"
     CDS             18210..18818
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072004.1"
                     /locus_tag="GA0074695_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2211"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_089006157.1"
                     /transl_table=11
                     /translation="MDYGRSERPAGAAPLPTAIKILIAGGFGVGKTTLVGAVSETRPLR
                     TEEVLTETGVGIDDLSGVESKRTTTVAMDFGRITISDDLVLYLFGTPGQDRFWFVWDEL
                     ALGALGAVVLADTRRLADCFPSIDYFEERGTPFVVAVNCFEGAKQFRLDEVQTALNLDP
                     GVPVVLCDARQRESAKEVLITLLEHAMKLREQRRRAFGG"
     gene            complement(18882..21737)
                     /locus_tag="GA0074695_RS10870"
                     /old_locus_tag="GA0074695_2212"
     CDS             complement(18882..21737)
                     /EC_number="4.2.1.3"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788270.1"
                     /locus_tag="GA0074695_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2212"
                     /product="aconitate hydratase"
                     /protein_id="WP_089006158.1"
                     /transl_table=11
                     /translation="MKEYDVASLDTFGAKTQLRVGDASYEIFKIGKVEGHDRLPYSLKI
                     LLENLLRTEDGANITADHIRQLGAWDPTADPSVEIQFTPARVLMQDFTGVPCVVDLATM
                     REAVRDLGGDATKVNPLAPAELVIDHSVIADLFGREDAFQRNVELEYERNKERYQFLRW
                     GQTAFNEFKVVPPGTGIVHQVNIEYLARTIMERNGQAYPDTVVGTDSHTTMVNGLGVLG
                     WGVGGIEAEAAMLGQPVSMLIPRVVGFKLSGEMPAGTTATDLVLTITEMLRKHGVVGKF
                     VEFYGPGVSAVPLANRATIGNMSPEYGSTVAIFPIDAETVRYLELTGRDPQQVALVEAY
                     AKEQGLWHDPAREPEYSERLELDLSTIEPSLAGPKRPQDRVPLGSAKTLFRSALADYVA
                     ADETGGDPSRTPGVPQLEKPFGADGPADEASAESFPASDSPANAVNDPADAPRDLERAA
                     VGSGGRVSNPVRVTGADGVEYELDHGAVVIAAITSCTNTSNPQVMIGAALLARNAVEKG
                     LSRKPWVKTTLAPGSKVVMDYYDRAGLTPYLEKLGFNLVGYGCTTCIGNSGPLPEEVSA
                     AVNEGDLAVVSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDIDLANEPIGED
                     SQGNPVFLRDIWPNSAEIQDVIASAIGASGFSSAYADVFAGDERWQSLPTPTGDTFAWD
                     GESTYVRKPPYFEGMAKDPKPVQDIAGARVLAKLGDSVTTDHISPAGSIKADSPAGKYL
                     AEHGVPRHEFNSYGSRRGNHEVMIRGTFANIRLRNQLVPGVEGGFTVNHLTGEQTSIYD
                     ASMAYQEAGVPLVILAGKEYGSGSSRDWAAKGTMLLGVKAVIAESYERIHRSNLIGMGV
                     LPLQFPVDTTAESLGLTGTETFTITGVTALNDGETPRTVKVTTDTGVEFDAVVRIDTPG
                     EADYYRHGGILQYVLRRMIAS"
     misc_feature    complement(21796..21814)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.7"
                     /tool="antismash"
     gene            21896..22252
                     /locus_tag="GA0074695_RS10875"
                     /old_locus_tag="GA0074695_2213"
     CDS             21896..22252
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287401.1"
                     /locus_tag="GA0074695_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2213"
                     /product="VOC family protein"
                     /protein_id="WP_089006159.1"
                     /transl_table=11
                     /translation="MIHHVLLACPRGSEDASRAFYVGLLGLVEKPKPPALAARGGCWFT
                     GYDAELHLGVEDDFRPARKAHPALLRPDLDALAARLAAAGHPVTWGDDEIPGMRRFHAY
                     DPHGNRLEFLAPAG"
     gene            22318..22980
                     /locus_tag="GA0074695_RS10880"
                     /old_locus_tag="GA0074695_2214"
     CDS             22318..22980
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072002.1"
                     /locus_tag="GA0074695_RS10880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2214"
                     /product="DedA family protein"
                     /protein_id="WP_231935110.1"
                     /transl_table=11
                     /translation="MAVVEVQHWLSALPPGVVYLIVAGVIGVESMGIPLPGEIVLVSSA
                     LLAAAGVVQPEWVATAAAAGAIIGDSVGYAVGRRGGRPLLARLGRRFPRHLGPAQLARA
                     EQSFARHGVWAVFFGRFVALLRILAGPLAGALRVPYRRFLVANAAGGLVWAFGTTYLLF
                     TVGRAAEHWLKDISWAGLAIAVLAGLGSTWWLRRRAHRLQSTEPSAAAEPVRAGTDH"
     gene            complement(23063..23701)
                     /locus_tag="GA0074695_RS10885"
                     /old_locus_tag="GA0074695_2215"
     CDS             complement(23063..23701)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287471.1"
                     /locus_tag="GA0074695_RS10885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074695_2215"
                     /product="C39 family peptidase"
                     /protein_id="WP_089006117.1"
                     /transl_table=11
                     /translation="MRTDILRKTALTVAGIAATAGGIAGPAIAAHAADAKPAAKPAAER
                     ELNVRYEAQPNFYYCGPAATRNALSVQGKDINVDAMAKEMGTTENGTNSINDITPVLNK
                     ETGKKDAYKSVEIRDSKADDKQTDKLRADIVRTIDDGRAVVANIAGTATDTDGTTHSFE
                     GGHYISVVGYRDDGKTVTIADSANPNMASYRMSVDNLADWIATRGYSAS"
     misc_feature    23736..23751
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     misc_feature    complement(23736..23752)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.99"
                     /tool="antismash"
     misc_feature    complement(23764..23779)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    complement(24133..24148)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
ORIGIN
        1 tcaccgagtc cggggtgcag ctgcggcagc gcggcggagc ccggcgccgc aagaaggcgt
       61 gacccgctca ccagcgtcgt ccaccagcgt cgtgctccgg gcggtccggt gacctccgca
      121 actaccggag tgcgactcga ctgcgacggg ccggtcgcga cggtcacgtt gtgccggccc
      181 gacgtgctca acgcgcaggc cccggcgatg tggcgcgcga tgagcgactt ctcccgcgag
      241 ctgcccggcg atgtccgggt ggtcgtggtg cgtggcgagg ggcgggcctt ctccgccggc
      301 ctcgacctgt ccgtggccgg cgcctccggc ccgggctcgt tcgccgagct cgccaccctg
      361 cccgagcagg agtgcgccga ccggatcgcc gagtaccagg ccgccttcac ctggctgcac
      421 cgccccgacg tgatctccgt cgccgccgtg caggggtatg cgatcggtgc cggattccaa
      481 ctcgccctcg cctgcgacct gcgggtgctc gccgaggacg ccaagctctc catggccgag
      541 gtgaccctcg gcctggtccc cgacctggcc ggcaccaagc ggctcgtcga gctggtcggc
      601 tattcccgcg cactggagat ctgcgccacc ggccgccgga tggacgccgc cgaggcggac
      661 cggatcggcc tggccaccct cgttgtgccg cccgcggagc tggacgccgc cgtgcgggac
      721 ctgaccgccg gcctgctggc caacagccgc gacgcgatcg tggagatcaa ggcgttgctc
      781 gccggggcgg ccgggcgtac gcacgcggat cagcagcggg ccgagcggga ggcgcagacc
      841 cggcggctgc gcgatctggc cgggcgcgga gaatagtaag gatcgttcgg gaagatccgg
      901 gttactcgcg aggttgtcgt agtggtcggg agaattgacc cgacggtcca ggcctgcccg
      961 acgacccgga ggtgacgggt gtccaaccac atggccggtg gcggcatggg cggctggagc
     1021 atgctccggt cgatgcgcga ccgcgaccag gtctccgccc accagctcaa gcgcggcacc
     1081 gcaaagcgga tcgtcgcgtt cgcccggccc taccggcgcg acatcgtcat cttcctgctc
     1141 accgtggtgg tcgccgcggt gatcggggtg gccaccccgc tgctcgccgg tgacgtcatc
     1201 gacgcgatcg ccggccgccg gccggacgct ggctcgaccg tggtccggct ggccctgatc
     1261 atcgccgtgc tggccgtggc cgacgcgctc ttctcgctgg cccagcgctg gtattcggcc
     1321 cggatcggcg agggcatcat cctcgacctg cggacccggg tctatgacca cgtccagcgg
     1381 atgccgctgc agttcttcac ccggacccag accggcgcac tggtcagccg gctcaacaac
     1441 gacgtgctcg gcgcccagcg ggcgttcacc tcgaccctgt ccggcgtagt gagcaacgtc
     1501 atccagctgg tgctcaccgc cggggcgatg ctcgtgctgt cctggcagat caccgcgttg
     1561 gcgctggtgc tgctgccgat cttcatcatc cccgcccgcc gggtcggccg gcggctcgcc
     1621 gagatcaccc gcgagtcgta caacctcgac gcgaagatga acgcgacgat gaccgagcgg
     1681 ttcggcgtcg ccggcgcgct gctggtcaag ctcttcggct cgcccgaggt ggaggcccgc
     1741 cggttcgccc gccgcgccga gcgggtccgc gacatcggca tccagtccgc catgtactcg
     1801 cggaccttct tcgtcgccat gctgctggtc gcctccctcg cccaggccct gacgtacggt
     1861 ctgggcggct ggctcgccgt cgccggcgcg gtcagcgccg gcaccgtggt caagctcgcg
     1921 ctgctgctca cccggctcta cgggccgctc accgcgctct ccaacgtccg ggtcgacgtg
     1981 atgagcgcgc tggtctcctt cgaccgcgtc ttcgaggtgc tcgacctgcg ccccggcatc
     2041 gaggagaagc ccgacgccgt gccgctgcct cggggcagtg gccgggtcga gttccgcgac
     2101 gtgcggttcc gctacccgag cgccgccgag gtgtccctcg cgtcgctcga ggaggtcgcc
     2161 gcgctcgacc gtacggtcaa cgagccggtg ctcaagggcg tctcgttcac cgtcgagccc
     2221 gggcagatgg tggccctggt cggcccctcc ggcgccggca agtcgacgct gtccatgctg
     2281 atctcgcgga tctacgacgc caccgacggc caggtgctgg tcggcggcgt cgacgtgcgg
     2341 gacgccaccc tcgcctcgct gcgcgacgag atcggcgtgg tcacccagga ttcccacctg
     2401 ttccacgaga ccatccggga gaacctgcgc tacgccaagc cggacgccac cgacgacgag
     2461 atctgggccg ccctggccgg cgcgcaggtg gccgacctgg tccgcgccct gcccgacggg
     2521 ctcgacacca tggtcggcga gcggggctac cgcttctccg gcggggagaa gcagcgcatc
     2581 gccatcgccc ggctgctgct caaggcgccg tcgatcgtga tcctcgacga ggccaccgcg
     2641 cacctggact cggagagcga ggcggcggtg cagcgcgcgc tgtccgtggc gctgaccggg
     2701 cgtaccgcgc tggtgatcgc gcaccggctc tccaccgtcc gggacgccga ccagatcctc
     2761 gtcctcgacg aggggcggat cgtcgagcgc ggccggcacg aggagttggt cgccgtcggc
     2821 ggcctctacg ccgagctgta ccgcacccag ttcgcggtgg ccgactcccc gaccccgtac
     2881 gccgagcccg agcagccgca gccggtggtc agcaccgtgc cgctcggcac gtacgtcgcc
     2941 caggaggcgc tgccgcccgc cacggccaac taagcgctca ccgccgcgcg tagctcggcg
     3001 aaggcggcgc cgagcgtctc cggggtgaag tgtgcgttca ggccgctcgg gttgggcagc
     3061 acccacagcc gggcgccgcc gagcggttcc ggctgtgggc cgaagccggc cttcggccgg
     3121 gcaaagccga ttcggtacgc ggtcaccccg accaccgcca cccagcgcgg ccggtaccgc
     3181 tcgaccttgc cggtcagctc cgccgcgccg gccaccagct ccgctgcggt cagctcgtcg
     3241 gcgcgggcgg tcgcccgggc caccatgttg gtgctgccca ggccgagggt gagcagctcg
     3301 tcctgttcac tggggtgcag ctggcgcggg gtgaagccgc cccggtgcag ggccggccag
     3361 aaccggttgc ccggccgggc gaagtgccag ccggtcgccg ccgaccacag ccccgggttg
     3421 atcccgacga agagcacgtc cagcccgggg gcgatcacgt ccggcagcag cttgtcgacc
     3481 gccgccgcga gttgttcctt cgtcggccgg ggatatcgcc gcgtggcgtt cacaggccgc
     3541 gcagcacgcc gccgtcgacc ggcacggtga cccccgtgac gtaaccggcg gcgggggaga
     3601 gcaggaaggc ggccacccgg ccgaactcgc ccggctcgcc gaaccggcgc agcgggatgc
     3661 cagcctctgc ctgcgcgcgg gtccgctccg ggtcgccgct ggcggcgagg agctcccggt
     3721 ttcggtcggt catgatcgat ccgggcagca ggctgaacac ccgtactccc cgcgggccgt
     3781 actcgtcggc gatgtccttg gccaccccgg ccaggccggg gcgcaggccg ttggagatgc
     3841 cgagcccggg cagcggcgcg cgcgccgacg tggacaggac cagcccgatc gcgccgccgc
     3901 tgctgagcgc ggcggccacc gtacgggtgg cgcggacgct gcccaggaag actgtctcga
     3961 aggacgcccg ccactgctcg tcggtggtct gggcggcggt gccccgaggt ggtccgccga
     4021 ccgagatcag cgccccgtcg agccggccga actgctcccg cgcggcggcg accaggcgtt
     4081 ccggcgtgcc cgggtccgtc aggtcggcgg tcagcccgat cgcccgttcc ggcccgccga
     4141 gcgccgcgac ggcagcggcc acctgttcag gttggcggga cgagatgacg acccgggcgc
     4201 cgtcggcgac gagctgttcg gcggtggcga agccgaggcc gcgggaggca ccggtcagca
     4261 cgtacacccg gtcggcgagt ccgagatcca tgcgtccgat cctgccgtac cccgcggtcg
     4321 gtcggccacc ccgcctcatc gacgggccgg gcggagcagg cgtacccggc cggcgagctg
     4381 caccgcgacg gcgccgccgg cccgggcgac ggccggcagc cggcggggcc ggggcgggtt
     4441 gcggccgtcg tagcgggcgg cggcctcgcg ggtggccagc tcctccgcgc ccaacggtgg
     4501 cagcgtgccg tggtcgcgca gcgcccgggc caggtcccag ccgtcgcgca gcgacccgtt
     4561 gccgggccgg ccggcggccc actcggtgaa cgtggccggc caggcggtgc cgagaccggc
     4621 ggcgagcagc ggccagtgtc gggccacctc gcccgcgcgc ttgcggagca gcgcccggcg
     4681 ggccgcctcc agcggcgcgg cggcgaaccc gggtggcacc ggcgcgccgg cgaccagcgc
     4741 cgcgacgagc tccgcctggc gggccgccag gccgtcgccc ggtgccgccg ggccgtcgcc
     4801 cggtgccgcc gggccgtcgc ccggtgccgc cgggccgtcg cccggtgccg ccgggccgtc
     4861 gcccggtgcc gccgggccgt cgcccggtgc cgccgggccg tcgcccggtg ccgccgggcc
     4921 gtcgcccggt gccgccgggc cgtcgcccgg tgccgccggg acggcaccgg gcggagcctc
     4981 gccgccggca tcccggccgg tcacgtgacc gccgggaagc cggacgcggc ggcgagggcg
     5041 tccagttcgg cgcgcagctc ggcggcgggc gggtagtggc cgtcccgttc cagcagcagc
     5101 gccgggggac gacggcgggc gcacagctcg cggaccaggt cgagcacctc ggcggggacc
     5161 gggtcggtgt gcgtgtcgtg gtagaaaccg ccctgctcgg caccgccggc cacgtgcgcg
     5221 taggcgatcc ggtccagcgg cagccggtcc agcaacgcgc ggggatcgcc gccccggttg
     5281 cgggcgttgg cgtgcacgtt ggcgaggtcg agcagcagca gcgccccggt cgcgtcgagg
     5341 atctcggtga ggaaggcggc ctcgtccagc tcgtcgtcgg gccagtcgaa cagcgcggcg
     5401 atcggctcca gcgcgagcgg caccggcagc tccgcctgcg ctcgccggac attcgccacc
     5461 accgcggcga ccgcctcccg gctgcgcggc agcggcagca ggtggccggc ctccaggccg
     5521 ccggcccgca cgaacgcgat gtgctcgctg accagcgggg cgtccagcgc cgcggccacc
     5581 ccggccaggt gggccacccg ggcggggtcg accggttccg cgccgccgag ggagagccgc
     5641 accccgtggg gtacgacggt gacgccgcgc tcgcgcagct cggcgaggcc gtgcgggagc
     5701 ggcccggccg gggtgagggt ctcggccacc acctcgacga agcacagccc gggcaggccg
     5761 gccacgaaac cggcgatctc cgaccgccag ccgatgccga ccccgtgcgg cccgggggag
     5821 ggtggtgacg tcgtggcacc cgtcggcgtc gggccggtca tccgccgcac ccgcctcccc
     5881 cgcaggagct gcccccgctg tccccgctgc tgcaggagct gcccccgcca cccgacgagc
     5941 agctgtagcc ggaggaggag ccactgctcg ccgcagcctg gtacttggcc tgggcttgct
     6001 gggcgaactc cgcgtcaagc gcccagagcg acgcggtgcc gaagagcgcc acccccatcg
     6061 cggcctccgc gctgccgtag gtggtgtacg cggggcgggc ggcgggggag aggtactggt
     6121 gcttcgcccg cagtccgcgc agggcgacgc gcccggcacg cgtacggttc ggcagccgcc
     6181 acagcgcgat cagcagcagg acgagtgcca gcacggtgag gatcagatat cccgtcgggc
     6241 gaccggccga cagccctgcc acgatccgga ccagaccgac caccagcagc accgacaggg
     6301 ccagcacgcc ggcccgggcg aactggcgtt ctccccggcc gacgagcagc ccccgctgtt
     6361 cgaggctgtc gcgtagcccg gccaacgcat cagcgacccg ctggtcgccg cgcaggtcgc
     6421 cggtgcgtgc tccccgtgcg gcagcccgat ggagggcccg ctgcagtgag gtcatcccgg
     6481 tgctcgtgta gcccgtcgcc gccagccgcc ctctggcgcg tacgccgacc acgcccgccc
     6541 ggcgcatcgc ggcgagcgcg gtccagatcg ccagttgcgc accgccgctg aggtaggccg
     6601 ccgactcggc gtcgagcggt tccttcgggg ttcgcccgcg gaggaccagg taccggtgga
     6661 ctccgcagac aaggaggatc acggccgccg ccgtgaggta gatcgcgagg aaggttggtc
     6721 ctgggatgcc ccaggtgtca tccgacgacg ccagcaccgt catggctcgc tcctgttgca
     6781 cgaggggtat cgcagcgtca ttgtggagca gccccgccag tgtggatccg gtcggtcagc
     6841 cgagttacca gactgagacc cgcccatggg tcgggcagcg ggcggtcagt ggcggcgtac
     6901 cgcctcctcg accaggtcga gcacccgacc caggtcgccg gccgggcgcc ccatcgttag
     6961 gtgcagcacc agcccgtcgt acgccagctc caggaactgg gccagcacgt cgatcggcac
     7021 gtcgtcccgg agcacgccgg cgtcgcgctg gcggaccagc cgctcacggg tcgcctcggc
     7081 gatggccgcg gagcgttccg cccagcgctt ggcgaacgcc gggtcggtac gcagccgccg
     7141 ggacacctcc agctggctgc cgagccagcc cgtggtgtcc ggggagaggg cccgggcgag
     7201 caggtcccgc atcacctgga cgaggccgtt gcgggcgacg gtctccacca tggcggatgc
     7261 gtcgtcctcg gcgacggcga ggaagaggga ctccttgtcg cggaagtggt ggaagatggc
     7321 gccgcgggag agccgggtgg cttcttccag gcgccggacg gtggcgccct cgtagccgtg
     7381 ccgggcgaaa cacgcccgcg cggcggcgag gatctcctgc cggcgcgcgt cgagctggtc
     7441 ctggcttact ctgggcacgg accgatcgtc gcaggcggcc tccgtagaag caaaccgtac
     7501 gtacggcttg agatgcgttt gcgtgatcag cagcgggacg cgcgccggtt accatcggcc
     7561 ggtgagccag gccgtccccc tccccgccca cccgttgacc gtcgccgccg tgcaggccga
     7621 gccggtgccc ggtgacgtcg ccggcaacgc cgccaccgcc gcccgcctcg tcggccgggc
     7681 cgccggcgcc cggatcgtcg tgctgccgga gctgttcctg ccgtcgtacc acccgccgac
     7741 cctcgcggcc gatccggccg ggaccgacgt ggccgccgac gaggtcggcg gagtggccga
     7801 cccgcggctg gacccgctcc ggggggtcgc ccgggacggc gggaccacgg tggtggtggg
     7861 cgccgcggtc cggcaccccg acgggcggcg caccatctcc gcgctggtgg tcgacccgac
     7921 cggcgcggtg cgggcggcgt acgacaagca gcagctctgg agcggggagc gcgagttgtt
     7981 cgacccgggc cggcgcggcg ccaccctgct ggtcgacgac tggcgcttcg ggctcgggat
     8041 ctgttacgac ggctgcttcc cggagcacgg gcgggccgcc gccgacgacg gcgcgcacgg
     8101 ttacctctgc ccgagcggct acctggccgg ctcggagcac cgccgggacc tctactacgc
     8161 cgcccgggcc ctggacaaca ccatgtacgt cgtcttcgcc aatgtcgtcg acggcgccga
     8221 cccgtggcgg ttcaacggcg gcgccgccgt gtacgacccg gaggggcggc cgttggcccg
     8281 aggcgcgaac accggggagg acgtgctggt ggcgacgctc gacccgaccg cgctcgcggc
     8341 cacccgggcg gcgcacacca tgctcgccga ccgccccgcc gatcccgggc tgccccgggc
     8401 cgcgctgccc gcctgaaagc cccgggccgc ggggcctgtc cgtggtgcgc ccggtcccgt
     8461 agggttcccg cgtgccgttg ctcctgctcg atctggacaa cactctgctc gaccgggacg
     8521 ggccgttccg tgcctggggc gcgcgcttcc tggacggcat cggcgcgccg cccgccgaca
     8581 tcgactggct gctgtccgtc gacgcggacg ggctggccga gcggtgggac gtcgcggacg
     8641 ccatccggga ccggtaccag ctcggcgtcc gtgccgtcga cctggtggag gagctgcacg
     8701 acggggtggt ggcggagacc cggttgagcc cgttggtcgc ctgcgcgctg cggatcgccg
     8761 acggcgccgg gtgggtgccg gtggtggtca ccaacggcgt ggtacgccag caggaggcga
     8821 agatccgccg taccggcctg gaccggcacg tcgccgactg ggtgatctcc gaggaggcgg
     8881 gggtcagcaa gcccaacccg aggatcttcg cgctcgccgc ccagcgggcc cggatgccgt
     8941 tgcgtggcgc ctgggtgatc ggcgacagcc cggaggcgga catcggcggg gcgaccgcgg
     9001 cggggctgcc cagcgtctgg ctgcaccggg ggcgccgctg gtcggactct cgcttcgcgc
     9061 cgacgcggtc ggccgacggg ttgatcgccg cggtggccgc ggcgctggcc gggtgaccac
     9121 gcgccgcagc gccggttgat cgggcggcgg ggcggttaat tgggttgacc cgcttgcgcc
     9181 cgccggtgag catggggccg cgcgagggcg cagccgggcg gagcccggtc gaggagagga
     9241 ggtcggtcat ggccgtcttt gcagggtcgt tccacctgcc tccaccagcc tcgatcgaag
     9301 gatcaactca accgtgcgtg atcacgactt cccggcgccg cagcgccgtg gccgcggcaa
     9361 gagccgcttc gacgacgacg aaccgtattt cctgaagcgc ggccggcacc ccgagccggt
     9421 cctggccgaa cccgacgacg agcccgacct cgaggaccgc tggtcctcct gggacgaggc
     9481 cgtgcacggg cccgaacccc accccgggtg gctggtcacc gagctggccg ccagggacac
     9541 cgaactcggg gtgctgaaga ccggcaagga ggcggacgtc cacctggtcc gccgggccgt
     9601 gccgggcacc gaccggtcct gcctgctggc ggccaagcgc taccgggacg cccagcaccg
     9661 gctcttccac cgggacgccg gctacctgga ggggcgccgg gtccgccggt cccgggagaa
     9721 ccgggcgatg gccggccgga cggcgttcgg ccggcagatg atcgccgggc agtgggcggc
     9781 cgcggagttc gccgccctcg cccggctctg ggagatcggc gccgcctccg ggcggatcgc
     9841 cgtgccgtac ccggtgcagc tgctcggcac cgagctgatg ctggagttcg tcggggacgc
     9901 cgaggagggg caggcggcgc cgcggctggc ccagctccgc cccgacgccg ccgagctgcg
     9961 cgacctctgg gagcagctgg tcgacgccct ggtggtgctg gcccgggcgg ggtacgcgca
    10021 cggcgacctg tcgccgtaca acctgctggt gcaccggggg cggctggtca tgatcgacct
    10081 tccgcaggtg gtcgacgtgg tggccaaccc gcagggcccg gacttcctgg cccgggacgt
    10141 ccgggtggtc ggcacctggt tcgccgcccg ggggctgccc gtcggcgacg ccgacccggc
    10201 cgagctgacc gggcggctgc tgcgggaggc gggcctgcgc tgagcggccg ggctgctgcg
    10261 ggaggcgggc cgctgcgtga gcgggccggg ctgctgcgcg aggcgggcct ccgctgagcg
    10321 catcgcggcc cggccctcgg gcgcgggacc gatcactgaa ggtagcgctc gacctcggag
    10381 agcgggcgct cgccctgggc gtccgggtcg ccgtgggcct ggcgggccgc gcgccggcgg
    10441 cgcagcaggt cccagcactg gtcgagggac tcctccagcg cccgcagccg ttcccgggcc
    10501 gcgtcgtcgg tgccggcctc gttctcctgg gccgccgccc gcagccggtg ctcctcgtcg
    10561 acgagttcgg agatccggtt caggatggtt ttgtcgtcca tgcccgaagc ttggcacagg
    10621 gggccgggcc gcgcccggtt tcccggcagg agacggcggc cgcgacgacc agcgggagtt
    10681 gcgcgggtga acatgccacc gcctctcctt agtggagagt ggaatcttcc tcactgaaaa
    10741 tttctcgtct cccgtctaga gaaagtcgtc gcgacaatgg caagcttccc ggagtcatca
    10801 ctcaaaacac tcgttccgcg acatgccgtt gcgaaggggg tccaacgcag gtgggagcag
    10861 caaccacagc gacccgaacc cggcgagcgg gatccgtgcc gctgcgccac gtcgtgccca
    10921 gcctgctcgg ggacccggct cagggactgg tgagcttcgg cgagcggtca ggaggcgagg
    10981 tggtccgact caatctcgga tcgttccggc ccttcctggt cacccaccca gagcacctgc
    11041 agcgggtgct gcgggagcgg gccgacaact acgtccgcgc cggtgacggc ctccagtggc
    11101 gtccgctcaa gcgcctgttc ggtgacggca tcctcagcga tggtcactac tggacagaca
    11161 gccggcacat tctccagccg ctgttcaccg cccggcggat cgactcgttg gtggaccgcc
    11221 tggccgagga gatcgacgag acggtcgccg agctggacgg gccggccgcc gacggccggc
    11281 cggtcgacat gggcgttgag caggcccgga tcgtgtgcca ggcgatcatg cgggtcttct
    11341 tcgccgacaa ggtctccgtg ccgcaggcca tgcggatcat ggaggcgcag gacgccatcg
    11401 cctcctctgt gatgccgcgc atcgccgtgc cgtgggcccc actggccatg ccgatgccgg
    11461 gtgaccgcaa gttccgccgc gcgctgcaga ccatcaacga caccctgctg ccgatcgtgc
    11521 gagccgcgcg ggagacggcc gagaccgacg gcgacgacat catctcgacg ctgtggcgca
    11581 gccggacgcc ggacggccgc cggctcgagg aatggcaggt ccgcaacgac accgtggcga
    11641 tggtcgccac caccaccgaa accaccatca gcgcactcac ctggctctgg ccacacctgg
    11701 aggcggaccc gcaggtcgcc gagcggctgc gcgaggagct cgaccgggtg gtcggcgacg
    11761 ctccggtacg gcgcgtccac ctcaaggacc tgcgctacac ccggcaggtc ctcgatgagc
    11821 tgctgcgcct ctacccggtc ggctggctct tcccccgccg ggctgtggag gaggatgtgc
    11881 tcggcggcgt tcgcatcccc gccgggtcga ccctcgtggt cagcccgctg atcacccacc
    11941 ggatgtcgat gttctgggac cggcccgagg tcttcgaccc ggaccggttc gccccggagc
    12001 gggtacgcac ccggcaccgc tacgcccact tcccgttcgg cggcggccca caccagtgcc
    12061 tcgggatgca cctgttctac ctggaggcgt tgctcatcgt ggccaccgtg ctcagccggt
    12121 accggttccg gctgcgccgg ccgcagctgc ccggcatcaa ggtcgccgcg gcgttgcgtc
    12181 ccaggaatcg ggtcgaggtg accctcgagc gggtgcgggg cgtggccgga tgacagtggc
    12241 caacgcggtc gacgaccaga tgcgcaacgc ggccgagcag ggccggatct gggcgctggc
    12301 ggcccgtggg cagcgggacc tcgccgaggt ggctggcgcg tacccggagc tcttcccggc
    12361 ccggccgttc gacgcggcgc tgttcagcaa cgtggcatcg gccatcgcct tcggcgcgcc
    12421 gtggtgcgac gcggcgagac tccggatcac caaccgtgcg gtgctctggg gcttcgccct
    12481 ggactggctg gtcgactacg tcgccacctc gcgcgaggag atcgaccaga tcagcgctcg
    12541 ctgcctggcg gtggccgacg gcggcacacc ggcccccgac gacccgctcg gcggcttcct
    12601 cgccgagttg cgggacgagt tggccaccgc gcccgcgttc gccgaggccc gcccgttgtg
    12661 gcgtggagag ctgcgcaagg tactggacgc gatggcccgc gagtgggact ggaaacatcg
    12721 gcccaccatg gacggcgggc cggccccgct gccgagcttc accgagtacc tggacaacgc
    12781 cgacaacctc gcctgcacgc tggtcaacgt cgcccactgg atctactccg gggacccggc
    12841 cacgctggcc aacctggagc agctgattga ggccagtgcc gaggtccagc gaatcctgcg
    12901 cctcgtcaac gacctcggta cgtacgagcg cgacctgcgc tggggggacc tgaacgccct
    12961 gatgctggtc gaggaccgca gtgaggtgca acgccggatc gacgagctgg tcggtcgggc
    13021 ccgagggctg ctggcgccgc tgcgcagcag ctgccccgag caggccgact acctcgcccg
    13081 gcagatcggc ttcagcagcg gattctaccg atccgccgac ttctggggtg cgctgtgacc
    13141 gacgcccacg ccgcgtcccc ggacgacgtg gacccggacg aacgctcggt cgacgggctg
    13201 gtcgccgcga tgggacggga cccggccggc cggctcagcc cgtcggtgta cgagaccggc
    13261 cgcctggtcg cactcgcccc gtggctcacc ggccacgcca gccggctgcg ccacctgctc
    13321 gaccggcagc gccccgacgg cggatggggc gcgccggagg ggtacgccct ggtgccgacg
    13381 ctgagcgcgg tggacgcgct gctgaccacc ctgaccgccg cgacaccggt cgaggtgccc
    13441 cgggacgacc tgcgggcggc cgccgttcga gggctggcca cgctcgccgg ctggcttggc
    13501 gcgggccagc ggatcaccgt gccggacacc ccggccgtcg acctgatcgt gcccgcactg
    13561 gtcgacgcgg tgaacgcgca tctgcgccgc gacgccgact tgctgcccgg cgctgcgccg
    13621 ctgctgctgc cggccgggat ggaccggcgc cgggccgacg cggtgcgcgg gctcgtcgcc
    13681 agcggccggc cggtgccgca gaagctgctg cacgccctgg aggtgctggg gcccgcggcg
    13741 cggcggcggg cggacgtcag accgctcacc ggcgcggtgg gggcgtcacc ggcggccacc
    13801 gcggcatggg tcggcgaccc cggccaaggg gcggatccgg cggcgctgac ctatctggac
    13861 accgcggtcg ggcggctcga cgggccggtg ccctgctgca cccccatcgc cgtcttcgaa
    13921 cgctcctggg tactggccaa cctggcccgg gcgggcgtac cggccgaccc ggcgcccgac
    13981 ctggtcgccg cgctggccgc gtcgctcggc ccggacggta cggcaaccgg ccccgggctg
    14041 ccggctgacg ccgacaccac ctcggtgacc ctgtacgccc tcgcccgcgc cggtcacccg
    14101 gtagaccccg gcagcctgtc ccggtacgac ctgggcagcc acttctgcac ctggcagggg
    14161 gaggacgggt cctccgtcac caccaacgcc cacgtgctgg aggcgctcgg ctggcacgcc
    14221 gcccaccgga ccgtccacgg cgacgcagcc gcccgccggc tgcccgccct ggccggctgg
    14281 ctgcgggagc agcagcaggc tgacggcaga tggtccgacc gctggcacgc ctcgccgtac
    14341 tatgccacgt cctgcgcagt gctggcgctg aaccggtacg cctcggccgc cgtcgccgcc
    14401 acgccggtgg gccgggcggt ggactgggtc gtcgacaccc agcgcgctga cggctcctgg
    14461 ggccggtggg cgggcacccg cgaggagacc gcgtacgcgc tccacgtcct gctcggcatc
    14521 gggccgacgg cccggcccgg ggtgccggcg gcggcccggc gcggggtggc gtacctggcg
    14581 gcgacggccg accagcggga cgacccgccg ctgtggcacg acaaggacct ctacgctccg
    14641 gtccgaatcg tgcgtgcggc gatcgccgcc gcgcggcatc tggccgccgc ccggcccgaa
    14701 ctgaccggtg tggacggtgg gcgatcgccg cgaggcgcaa ccttcatgat caggaacgct
    14761 tgagtgcgac ccgcgacgct gctagcgtgc gccggggtcg atgcgtgcgt tttgcgacgc
    14821 gctgccgacc gccgacgagc acagggccag gccaggatgg tgtgatgcgt ttccgcagtt
    14881 cgaatctgcg tacgaaggtt gttgccctgc tcgcctcgct ggtggcgctc tgggccttca
    14941 cggcctgggt caccgtccgc gacggggtca acctggtcgg cgtgcaggcg ctggacagca
    15001 aggtcttcga ccccaccgag ccgctgctgc tccagctgca gctggagcgc cggacgtcgc
    15061 tgaccttcct cggtagcccc ggtgaagagc agcggtccca gctggcggag atccgccaac
    15121 gcaccgacca gctggcgcag gagttcgagg aatccgttga caactggcag gtcggcctgc
    15181 ttggcagcga cacgctggac cagcgtatcg acgagctgat ccgcgggctg gaggacctgc
    15241 cggcgacccg cgcggccgtc gacgacaaga gcatcgaacg ggcggccgcc ggtgccgcct
    15301 tcaccggcgt gatcgaagcg atctaccggg tctacgacgc gctcggcaag ctggatgacg
    15361 agcaggcggc cgaggacacg gccgcgctga tcgggctcaa ccgcgcccgc gagctgctgt
    15421 cccaggagga cgctctgctc gccggcgcgc tggcggccgg ccggatcacc ccggccgagc
    15481 aggcgcagtt cgcccaggtg gtcggcgctc ggcggttcac cgcggaacag gcgatcaccc
    15541 ggctgccggc cgccgaccag caccggtacg agcagatgct cgccggtccc accttcgtca
    15601 aactgaccga cctcgagacg aaggtcatgc agggcggggg cacccggccg ccgctgagcg
    15661 ccgcggcctg ggaccgggcg gcgtcgcccg cgctcaacga gatcggccag gtcgtgctgg
    15721 ccggcggtga cgacatcgtg gaccgcgcgg tgccgatcgc catctgggtc atcctccggc
    15781 tggtgctggc cgccggtctc ggcctgctcg ccgtcatcgc gtccatcgtg gtctcgatca
    15841 ccaccgcccg cgcgctcgtc cagcagctgg aacggctgcg cgaggcggcg ttccggctgg
    15901 ccaacgagcg gctgcccggc gtggtggagc ggctcggccg gggcgaggag gtcgacgtcg
    15961 cgcgggaggc acccccgctc gagttcggcg acgacgagat cgggcaggtg ggcaaggcgt
    16021 tcaacgtcgt gcaggagacc gccgtccgga ccgccgtcga gcaggccgag ctgcgccgca
    16081 acgtccgcga ggtgttcctc agcctggccc ggcgtaccca ggcgctggtc caccgccagc
    16141 tcaccctgct cgacgcgatg gaacgccgcg agcacgacgc cgaggagctg gaggacctgt
    16201 tccgcgtcga ccacctggcg acccggatgc ggcgcaacgc cgagaacctg atcgtcctct
    16261 ccggctccac gcccgggcgg tcctggcggc gcaacgtgcc gatggtggac gtcatccgcg
    16321 gcgcggtggc cgaggtcgag gactacaccc gggtgaacgt gctgccgatc gggccggtgt
    16381 cgctgaccgg tcgggcggtc ggtgacatca tccacctgct ggccgagctg atcgagaacg
    16441 gcctctcctt ctcgcccccg cacaccgctg tcgaggtacg tgggcagctg gtggcgaacg
    16501 gcttcgccat cgagatcgag gaccggggcc tgggcatgag cgaggaggag ttggccgccg
    16561 cgaaccaccg catcgtcgac cgttccgagc tgaacctggc caacgccacc cggctcggcc
    16621 tgtacgtggt cagccggctc accgagcggc acggcgtgaa ggtgcagctc aaggagtccg
    16681 cgtacggcgg tacgaccgcc gtggtgatga tcccgctcga gctggtcacc gtcgacgaac
    16741 cggacgccag cacgtcgggc ggcttccggg cgggcgccgg gaccgcgccg gccgggaacg
    16801 agccggcggc agccggcgcg ccggagggcc ggccggccgg ggcgacgctc gagctgccga
    16861 ccgtcccggt ggcggtcgcc gaaacgacca gcgcgccgca gccaggggac gagcccgtgg
    16921 gcgcggcgga gccgccggcg actccggtcg gcgccgaggc gccggcgctg accccgtccg
    16981 ggctgccggc gcgcacccgg aggcggcagc cgacggccga ggggccgggc gcgccggcgg
    17041 ggctccccac cgcggacacg tcggcggagg gcacgggcgc ggcgggtgac gccccggcgc
    17101 ggacccacgt cggcctgccg gtgcgggtac gccaggcgag cctcgtgccg gagctgcggc
    17161 aggaaccgtc caccccggac accgaccagg acgaggacga agcggtgcgc ccgcccgagc
    17221 aggtgcgccg gatgatgagc tcctaccaga gcggcacccg acgcggccgg accgacgccg
    17281 cgcggctgct cggcggggcg cacggagccg gcgacgggcc ggactccggc gacgggcaga
    17341 cgatctgagg gaaaacgccg tggcggcgga tcccagacga gtacggcgac aacagccggg
    17401 ggagaagagg acgacgagtg gggcagaaga cggcttcgag cgcagacctg acgtggttgc
    17461 tggatgacct ggtcggccgg gtcaagcagg cggaacatgc cgtggcgctg tccaccgacg
    17521 gcctgctgat ggcctcgtcg caagggctga gccgggacga cggcgagcac ctggcggcga
    17581 tggcggcggg catccagagc ctggcccggg gtgcgggcaa gcggttcggc ggcggccagg
    17641 tgcagcagac catcatcgag atgcagtcgt cgttcctctt cgtcaccgcg gccgggcgca
    17701 acgcctgcct ggccgtgctg gcctccgagg acgccgacgt cggcctgatc gcgtacgaga
    17761 tggcgatgct ggtgacccgg gtcggccggt tcgtcgcctc gcccacccgg gaaaccgcca
    17821 tcggcgagaa cccggcacga tgaccggcca ggcggagtcc gccgagcagg aatgggtgga
    17881 cgaccacgcg ggtccggtgg tgcgcccgta cgcggtgacc ggtggccggg cccgcccggt
    17941 caccggcacc ttcgacctga tctccctggt caccgcgacc cgggcggatg tgagcgcgga
    18001 gtccgggctg ggcccggagc acctggcgat cgtcggcctc tgccagcgga tgcagtccgt
    18061 ggccgagatc gccgcccacc tcgacctgcc ggtgggcacc gtccgggtcc ttctcggtga
    18121 cctggtggcc cgtcacctgg tgcaggtccg tgagccgcgc gcgacccccg ccggccttcc
    18181 cgacgacagc gttttcgagg cggtaatcaa tggactacgg gcgctctgag cggccggcgg
    18241 gagcggcgcc gctgcccacc gcgatcaaga tcctgatcgc cggcggcttc ggcgtcggca
    18301 agaccaccct ggtcggcgcg gtgagcgaga cgcgcccgct gcggacggag gaggtgctga
    18361 ccgagaccgg cgtcggcatc gacgacctct ccggagtgga gagcaagcgg accaccaccg
    18421 tggcgatgga cttcggtcgc atcaccatca gcgacgacct ggtgctctac ctgttcggca
    18481 cgcccggcca ggaccgcttc tggttcgtct gggacgagct ggcgctcggc gcgctcggcg
    18541 cggtggtgct ggccgacacc cggcgactgg ccgactgctt cccgtcgatc gactacttcg
    18601 aggagcgggg cacgcccttc gtggtggcgg tgaactgctt cgagggagcc aagcagttcc
    18661 ggctcgacga ggtgcagacc gcgctcaacc tcgacccggg ggtgccggtg gtgctctgcg
    18721 acgcacggca gcgggagtcg gccaaagagg tgctgatcac gctgctggag cacgccatga
    18781 agctgcgcga gcagcgccgc cgcgccttcg gcggctgacc ccccgacgcc gcagggcccc
    18841 tccccgcgct cgcgggaagg ggccctgtcc ggggtacgac gtcagctggc gatcatgcgg
    18901 cgcagcacgt actgcaggat gccgccgtgc cggtagtagt ccgcctcacc cggggtgtcg
    18961 atgcggacca cggcgtcgaa ctccacgccg gtgtcggtgg tgaccttgac cgtacgcggg
    19021 gtctcgccgt cgttcagcgc ggtgacgccg gtgatggtga aggtctccgt gccggtgagg
    19081 cccagcgact cggcggtggt gtcgaccggg aactgcagcg gcaggacccc catgccgatc
    19141 aggttcgagc ggtggatccg ctcgtacgac tcggcgatga ccgccttgac gccgagcagc
    19201 atggtgccct tggccgccca gtcgcgggac gagccggagc cgtactcctt gccggccagg
    19261 atgaccagcg ggacgcccgc ctcctggtag gccatcgagg cgtcgtagat cgaggtctgc
    19321 tcgccggtca ggtggttgac cgtgaagccg ccctcgacgc cgggcaccag ctggttgcgc
    19381 agccggatgt tggcgaaggt gccccggatc atcacctcgt ggttgccccg gcgcgagccg
    19441 tacgagttga actcgtgccg cggcacgccg tgctcggcga ggtacttccc ggcgggggag
    19501 tccgccttga tcgagccggc cggggagatg tggtcggtgg tcaccgagtc gcccagcttg
    19561 gccagcaccc gggcgccggc gatgtcctgc accggcttcg gatccttcgc catgccctcg
    19621 aagtacgggg gcttgcggac gtaggtggac tcgccgtccc aggcgaaggt gtcgccggtc
    19681 ggggtcggca gcgactgcca ccgctcgtca ccggcgaaca cgtcggcgta cgccgagctg
    19741 aagccgctgg caccgatcgc cgaggcgatg acgtcctgga tctcggcgct gttcggccag
    19801 atgtcccgca ggaacaccgg gttgccctgg ctgtcctcgc cgatcggctc gttggccagg
    19861 tcgatgtcca tggtgccggc gagcgcgtac gcgaccacca gcggcgggga cgccaggtag
    19921 ttcatcttga cgtccgggtt gatccggccc tcgaagttgc ggttgccgga gagcaccgac
    19981 acgacggcga ggtcaccctc gttgaccgcg gcggagacct cctccggcag cgggccggag
    20041 ttgccgatgc aggtggtgca gccgtagccg accaggttga agccgagctt ctccaggtag
    20101 ggggtgaggc cggcccggtc gtagtagtcc atgacgacct tggagcccgg ggccagggtg
    20161 gtcttcaccc acggcttgcg ggacaggccc ttctccaccg cgttcctggc cagcagcgcg
    20221 gcaccgatca tgacctgcgg gttcgaggtg ttggtgcagg aggtgatcgc cgcgatcacc
    20281 acggcgccgt ggtccagctc gtactcgacg ccgtcggcgc cggtcacccg gaccgggttg
    20341 ctgacccggc caccggagcc gaccgccgcc cgctccaggt cgcgcggggc gtcggccggg
    20401 tcgttgacgg cgttggccgg ggagtcgctg gccgggaagg actcggcgct ggcctcgtcg
    20461 gccgggccgt cggcgccgaa cggcttctcc agctgcggca cgcccggcgt acggctcggg
    20521 tcacccccgg tctcgtcggc ggccacgtag tccgccagcg ccgaccggaa gagggtcttg
    20581 gcgctgccca gcggcacccg gtcctgcggg cgcttcgggc cggccaggga cggctcgatc
    20641 gtgctcaggt cgagctccag ccgctcggag tactccggct cgcgggccgg gtcgtgccag
    20701 aggccctgct ccttggcgta cgcctcgacc agcgcgacct gctgcgggtc gcggccggtc
    20761 agctccaggt agcggacggt ctcggcgtcg atcgggaaga tcgcgacggt ggagccgtac
    20821 tccggcgaca tgttgccgat ggtggcccgg ttggccagcg gcaccgcgct cacgcccggg
    20881 ccgtagaact cgacgaactt gccgaccacc ccgtgcttgc gcagcatctc ggtgatggtg
    20941 agcaccaggt cggtggcggt ggtgccggcc ggcatctcgc cggagagctt gaagccgacg
    21001 acccgcggga tcagcatgct gaccggctgg ccgagcatcg cggcctcggc ctcgatgccg
    21061 ccgacgcccc agccgagcac gcccaggccg ttgaccatgg tggtgtgcga gtcggtgccg
    21121 accaccgtgt ccgggtacgc ctggccgttg cgctccatga tcgtgcgggc caggtactcg
    21181 atgttgacct ggtgcacgat gccggtgccc ggcgggacga ccttgaactc gttgaacgcg
    21241 gtctggcccc agcgcaggaa ctggtagcgc tccttgttgc gctcgtactc cagctcgacg
    21301 ttgcgctgga aggcgtcctc gcggccgaac aggtcggcga tgacggagtg gtcgatgacc
    21361 agctcggccg gggcgagcgg gttcaccttg gtggcgtcgc cgccgaggtc gcggacggcc
    21421 tcccgcatgg tggccaggtc gacgacgcag ggcacgccgg tgaagtcctg catcagcacc
    21481 cgggccgggg tgaactggat ctccacgctc gggtcggcgg tggggtccca cgcgccgagc
    21541 tgccggatgt ggtcggcggt gatgttcgcg ccgtcctcgg tccgcagcag gttctccagc
    21601 aggatcttca agctgtaggg cagccggtcg tggccctcca ccttgccgat cttgaaaatc
    21661 tcgtagctcg cgtctccgac gcgtagctgg gtcttcgcac cgaaggtgtc gaggctcgcc
    21721 acgtcgtact ccttcacacc agcgaccgtg agtagtcctg agcagtctgt cgcaccggcc
    21781 ggtgtgttgc tgtggttagg cgacacttac ctgcgtccgg cgctcaacaa aaccgtacgt
    21841 ccgtcttgct atccgtgcaa cctcgtgcca gggtctggaa cgaggaggtg ccaccatgat
    21901 ccatcacgtg ctgctcgcct gcccacgcgg ctccgaggac gcgtcccggg ccttctacgt
    21961 cggcctgctc ggcctggtcg agaagcccaa accgccggcc ctcgccgccc gcggtggttg
    22021 ctggttcacc gggtacgacg cggagctgca cctcggcgtc gaagacgact tccggcccgc
    22081 ccggaaggca catcccgccc tgctccgccc cgacctcgac gcgctcgccg cccggctggc
    22141 cgccgccggc cacccggtca cctggggtga cgacgagatc cccggcatgc gaaggttcca
    22201 cgcgtacgac ccgcacggca accgcctgga gttccttgcc ccggccggct gatcgccgga
    22261 tgagcggacc gccggtacgc cggacccgag gtagggttcg aggtcggatc gcagggggtg
    22321 gcagtggtag aggtgcagca ctggctctcc gcgctgcccc cgggcgtggt ctacctgatc
    22381 gtcgccgggg tgatcggcgt ggagagcatg ggcattccgc tgcccggcga gatcgtcctg
    22441 gtcagctcgg cgctgctggc cgccgccgga gtggtgcagc cggagtgggt ggccaccgcc
    22501 gccgcggccg gcgccatcat cggcgactcc gtcgggtacg cggtgggccg gcgcggtggc
    22561 cgtcccctgc tcgcccggct gggccggcgc ttcccccggc acctcggccc ggcacagctc
    22621 gcccgcgccg agcagagctt cgcccggcac ggcgtctggg cggtcttctt cggccggttc
    22681 gtggccctgc tgcggatcct cgccgggccc ctggccggcg cgctgcgcgt gccgtaccgc
    22741 cggttcctgg tggcgaacgc ggccggcggc ctggtctggg ccttcggcac gacctacctg
    22801 ctgttcaccg tcggccgcgc ggccgagcac tggctcaagg acatctcctg ggccgggctg
    22861 gccatcgcgg tgctcgccgg cctcggcagc acctggtggc tgcggcgccg ggcccaccgg
    22921 ctgcagtcga cggagccgtc cgccgcggcc gagccggtac gggccggcac cgaccactga
    22981 cccgtggacg gcaacggccg gccgggtgtg gagacggtga agggccggcc cccgggtggg
    23041 ggccggccct tcgttcgttg gctcaggagg ccgagtagcc gcgggtggcg atccagtcgg
    23101 cgaggttgtc gacgctcatc cggtaggagg ccatgttcgg gttggcggag tcggcgatgg
    23161 tgacggtctt gccgtcgtcg cggtagccca cgacgctgat gtagtggccg ccttcgaagg
    23221 agtgggtggt gccgtcggtg tcggtggcgg tgccggcgat gttggcgacc acggcgcggc
    23281 cgtcgtcgat ggtgcggacg atgtcagcgc gcagcttgtc ggtctgcttg tcgtcggcct
    23341 tgctgtcgcg gatttccacc gacttgtagg cgtccttctt accggtttcc ttgttcagga
    23401 ccggggtgat gtcgttgatg ctgttggtgc cgttctcggt ggtgcccatc tccttggcca
    23461 tggcgtcgac gttgatgtcc ttgccctgga cggagagggc gttacgggtg gcggcggggc
    23521 cgcagtagta gaagttcggc tgggcctcgt agcgcacgtt cagttcccgc tccgccgcgg
    23581 gcttggcggc cggcttggcg tcggcggcgt gggcggcgat ggcggggccg gcgatgccac
    23641 cggcggtggc ggcgatacca gcaacggtca gcgcggtctt acgcagaatg tcggtacgca
    23701 tgatgatgaa agcctttcgc tcgggggtac gcgcgacacc ccaagggggt gtgggtgcca
    23761 cgggtgaaag gaaagtcagg agaggggatt cgcagccggc ggccaagggc ctgctggcgg
    23821 atgtcccggg ggtgtaacga ccgggggccg gggatcattc caccgggctc ccgggggccg
    23881 gccctgctcg ggcggccggg ggatgtaacg acggccggtg gcggatcatt ccacccgggc
    23941 cgacggccca tgctcggtgg gccggtgacc agcgcggctg tcccacgcgg tcgaccatgt
    24001 ccaacgcccc ggaccccgcc gtcattccga gccagccccg ggcaggccga caggccgcca
    24061 cgaaccggac accccacccc cggcgcaacc tcgcattccg ggcagccatg ccgtcagtgg
    24121 aacaccatgg gtgtcaaaac cacctgacga cacccatggc gttccaccca caccccgggc
    24181 tctctggaca gggtgcccgc acacacggcc cgggacggta gccactcgac gaggctcgcc
    24241 ggcccgggcc gcaggcccag atcgtcgctt cgaacctcga caccgcgggc ccgggcggac
    24301 gggtcaaccg gtgtgcggcg cctcgacgtc accgtcccgc cccatgcgcc ggtcttcggc
    24361 gcagccggcc aacgccgggc atggcagtca gtggaacgtc attgctgcca aaaggccccg
    24421 gcaccccaca acgttccact cacgaccaag gtgcgacagg agcgccgccg acacacggag
    24481 tgggcctggc cgcgagcctc ggcagcgatg tgtcggcggc cgcgtgccac catgtggacc
    24541 atggagatct ggcacaaccc gtcctgctcg aagtgcgcca ccgcccgggc gacgctggac
    24601 gaggcgcggg tgccctaccg gctgcgggcg tacctgaccg agccgccgag cgcgggcgag
    24661 ctgaccgagg tgctgcgccg gctgggcgcc cgggcctggg acatctgccg caccggcgag
    24721 ccggccgcgg cggccctggg catggccgac tggccccgag acg
//
