LOCUS       NZ_FMCU01000051         4922 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000051
VERSION     NZ_FMCU01000051.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 4922
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000051.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..4922
                     /db_xref="taxon:121616"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070216_151"
                     /organism="Micromonospora matsumotoense"
                     /strain="DSM 44100"
                     /type_material="type strain of Catellatospora
                     matsumotoense"
     region          1..4922
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..4922
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..4922
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[15:>4922](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16..>4922
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            16..>4922
                     /locus_tag="GA0070216_RS33480"
                     /old_locus_tag="GA0070216_1511"
     CDS             16..>4922
                     /NRPS_PKS="Domain: PCP (183-248). E-value: 2e-25. Score:
                     80.8. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33480_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (262-555). E-value:
                     5.2e-109. Score: 355.8. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33480_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (726-1112). E-value:
                     1.5e-101. Score: 331.9. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33480_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1218-1287). E-value: 8.9e-24.
                     Score: 75.5. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33480_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1301-1596). E-value:
                     1.1e-98. Score: 321.9. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33480_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="GA0070216_RS33480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1511"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_245722907.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-67, bitscore:
                     213.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-112, bitscore:
                     362.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-19, bitscore:
                     55.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAFVLDDRLKPVPVGVAGELYVAGAALARGYVGQAGLTAERFVG
                     CPFGSGERMYRTGDRVRHLPDGRLVFLGRVDDQVKIRGYRVEPGEIHTVLVAHPDVRQA
                     AVLLRDDRLVAYVVGGDGSGLREWVAQRLPEHMVPSTVVVLDALPLTSNGKLDRSALPT
                     PDRTAPAGVDRDSLDPRTELLRVAFADVLGLDHVGVDDDFFDLGGHSLLAVRLISRIRM
                     VFHADVRLRTLFDAPTPARLAARLSDADQARLALGVQIRPERMPLSYAQRRLWFINQLE
                     GPSVTYTMPVVLRLSGDVDPAALDAALRDVITRHEVLRTVFATVDGEPYQRVVDPTDLD
                     WSLELATGESDAIAAATGYRFNLAQEIPIRAWLFDQQTLVVVVHHIAGDGWSWEPLARD
                     LSTAYAARRAGSPPDWRPLPVQYADYALWQRELLGDPDNPDSVAGRQLTYWRDRLADVP
                     EELNLPVDRPRPATAGHEGHSIDLTVPAAVHVRLRALARAEGVTVPMVVQAALAVLLSR
                     LGAGTDVPIGSVVAGRTDEALDDLVGFFVNTLVLRTDLSGDPAFTELLARVRDTAVAAL
                     EHQDVPFDRLVEELAPARSLSRHPLFQVALNVQNQVEASLDIVGADAYRLSAGTRAIRF
                     DLEFSLRETLNADGAPLGLRGVVRGSADLFEADTVRRLVDRFVRVLGTVAAEPGTRLSA
                     VILLDDAERHDVLTGWNATGARIDPTSVPALIAAQVAATPDAPAVHFGGALLSYADLGA
                     RADRLARVLVAHGVGPETVVALRLPRGFDMIVALLAVWRAGGAYLPIDPETPTERLAYV
                     VEDAQPVAIVATPATAGAVPAGPHLILIDALPDDADDVSLPEWGHGGQAAYVIFTSGST
                     GRPKGVLVDHDALTNFVSAIADHLEITPGTAMLQYASFSFDMSVMDIVVPLSRGGTVVV
                     PSEAERAEPELLRALVAASGARTATLVPSLLGVLEPDDLAGVRVLFVGGEVVDPALAAR
                     WAPGRKLVHMYGPTETTIVMAVDAIDPQRPGPLPLGGPLANSRVFVLDHALAPVPVGVV
                     GELYIAGSQLARGYVGRAALTSERFVACPFGAGERMYRTGDLVRWNADGELVFAGRADD
                     QVKIRGFRIELGEVQAALTAHPAVHQAVVVVREDSPGERRLVGYVTGGADLDIEAVQGF
                     VAARLPEYMVPTLVVLAGMPLTSSGKVDRRALPVPVVVERRPGSGRGAMTPHEELLCAA
                     FAAVLGRDAVGVDEDFFALGGHSLMAVRLAGRVRTVLGVEVPLRTLFEAPTPRALAVRL
                     SSAEDQARPALTSVERPARVPLSFAQRRLWFISRLEESTAAYHVPIVLRLDGVDPVALE
                     LALRDVLARHEVLRTVLPMVDGEPFQQIIPVDELDWRLTIAETDDQDAAVSAAIAEPFD
                     LTAEVPVRAWLFDGSVLVLVVHHVAADGWSMAPLARDLSQAYAARRVGQVPGWSPLPVQ
                     YADFAVWQRGLLGVESDVGSVGSRQVGFWRGVLAGVPQELRLPVDRVRPVVAGRGGCGV
                     GLVVSAGVHARVVEVARVEGVTVFMVLQAALAVLLSRLGAGVDVPVGTVVAGRVDEALD
                     EVVGFFVNTLVLRTDVSGDPSFVELLGRVREVGLSAFEHQDVPFERLVEELAPERSL"
     CDS_motif       55..144
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0001"
                     /evalue="1.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="43"
                     /protein_start="13"
                     /score="46.0"
                     /tool="antismash"
                     /translation="PVGVAGELYVAGAALARGYVGQAGLTAERF"
     CDS_motif       226..288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0002"
                     /evalue="7.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="91"
                     /protein_start="70"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FLGRVDDQVKIRGYRVEPGEI"
     CDS_motif       475..501
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0003"
                     /evalue="4.00E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="162"
                     /protein_start="153"
                     /score="4.1"
                     /tool="antismash"
                     /translation="GKLDRSALP"
     aSDomain        565..759
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33480_PCP.1"
                     /evalue="2.00E-25"
                     /label="GA0070216_RS33480_PCP.1"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="248"
                     /protein_start="183"
                     /score="80.8"
                     /tool="antismash"
                     /translation="LRVAFADVLGLDHVGVDDDFFDLGGHSLLAVRLISRIRMVFHADV
                     RLRTLFDAPTPARLAARLSD"
     CDS_motif       742..795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0004"
                     /evalue="8.00E+00"
                     /label="C5_dual_260-291"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="260"
                     /protein_start="242"
                     /score="0.0"
                     /tool="antismash"
                     /translation="AARLSDADQARLALGVQI"
     aSDomain        802..1680
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33480_Condensation_L
                     CL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.20E-109"
                     /label="GA0070216_RS33480_Condensation_LCL.1"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="555"
                     /protein_start="262"
                     /score="355.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAGDG"
                     /tool="antismash"
                     /translation="ERMPLSYAQRRLWFINQLEGPSVTYTMPVVLRLSGDVDPAALDAA
                     LRDVITRHEVLRTVFATVDGEPYQRVVDPTDLDWSLELATGESDAIAAATGYRFNLAQE
                     IPIRAWLFDQQTLVVVVHHIAGDGWSWEPLARDLSTAYAARRAGSPPDWRPLPVQYADY
                     ALWQRELLGDPDNPDSVAGRQLTYWRDRLADVPEELNLPVDRPRPATAGHEGHSIDLTV
                     PAAVHVRLRALARAEGVTVPMVVQAALAVLLSRLGAGTDVPIGSVVAGRTDEALDDLVG
                     FFVNTLVLRTDL"
     aSModule        802..3876
                     /complete
                     /domains="nrpspksdomains_GA0070216_RS33480_Condensation_LCL
                     .1"
                     /domains="nrpspksdomains_GA0070216_RS33480_AMP-binding.1"
                     /domains="nrpspksdomains_GA0070216_RS33480_PCP.2"
                     /locus_tags="GA0070216_RS33480"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       817..846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0005"
                     /evalue="1.10E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="277"
                     /protein_start="267"
                     /score="8.6"
                     /tool="antismash"
                     /translation="SYAQRRLWFI"
     CDS_motif       871..984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0006"
                     /evalue="5.10E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="323"
                     /protein_start="285"
                     /score="54.2"
                     /tool="antismash"
                     /translation="TYTMPVVLRLSGDVDPAALDAALRDVITRHEVLRTVFA"
     CDS_motif       1162..1227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0007"
                     /evalue="3.80E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="404"
                     /protein_start="382"
                     /score="32.2"
                     /tool="antismash"
                     /translation="VHHIAGDGWSWEPLARDLSTAY"
     CDS_motif       1276..1314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0008"
                     /evalue="3.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="433"
                     /protein_start="420"
                     /score="19.6"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       1582..1671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0009"
                     /evalue="2.20E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="552"
                     /protein_start="522"
                     /score="45.7"
                     /tool="antismash"
                     /translation="DVPIGSVVAGRTDEALDDLVGFFVNTLVLR"
     CDS_motif       1720..1836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0010"
                     /evalue="4.20E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="607"
                     /protein_start="568"
                     /score="70.6"
                     /tool="antismash"
                     /translation="RDTAVAALEHQDVPFDRLVEELAPARSLSRHPLFQVALN"
     aSDomain        2194..3351
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33480_AMP-binding.1"
                     /evalue="1.50E-101"
                     /label="GA0070216_RS33480_AMP-binding.1"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1112"
                     /protein_start="726"
                     /score="331.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AAQVAATPDAPAVHFGGALLSYADLGARADRLARVLVAHGVGPET
                     VVALRLPRGFDMIVALLAVWRAGGAYLPIDPETPTERLAYVVEDAQPVAIVATPATAGA
                     VPAGPHLILIDALPDDADDVSLPEWGHGGQAAYVIFTSGSTGRPKGVLVDHDALTNFVS
                     AIADHLEITPGTAMLQYASFSFDMSVMDIVVPLSRGGTVVVPSEAERAEPELLRALVAA
                     SGARTATLVPSLLGVLEPDDLAGVRVLFVGGEVVDPALAARWAPGRKLVHMYGPTETTI
                     VMAVDAIDPQRPGPLPLGGPLANSRVFVLDHALAPVPVGVVGELYIAGSQLARGYVGRA
                     ALTSERFVACPFGAGERMYRTGDLVRWNADGELVFAGRADDQVKIR"
     CDS_motif       2377..2418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0011"
                     /evalue="4.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="801"
                     /protein_start="787"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LAVWRAGGAYLPID"
     CDS_motif       2599..2658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0012"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="881"
                     /protein_start="861"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGRPKGVLVDH"
     CDS_motif       3145..3234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0013"
                     /evalue="9.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1073"
                     /protein_start="1043"
                     /score="49.9"
                     /tool="antismash"
                     /translation="PVGVVGELYIAGSQLARGYVGRAALTSERF"
     CDS_motif       3316..3378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0014"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1121"
                     /protein_start="1100"
                     /score="36.5"
                     /tool="antismash"
                     /translation="FAGRADDQVKIRGFRIELGEV"
     CDS_motif       3586..3612
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0015"
                     /evalue="9.10E-02"
                     /label="NRPS-A_a10"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1199"
                     /protein_start="1190"
                     /score="5.8"
                     /tool="antismash"
                     /translation="GKVDRRALP"
     aSDomain        3670..3876
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33480_PCP.2"
                     /evalue="8.90E-24"
                     /label="GA0070216_RS33480_PCP.2"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1287"
                     /protein_start="1218"
                     /score="75.5"
                     /tool="antismash"
                     /translation="EELLCAAFAAVLGRDAVGVDEDFFALGGHSLMAVRLAGRVRTVLG
                     VEVPLRTLFEAPTPRALAVRLSSA"
     aSDomain        3919..4803
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33480_Condensation_L
                     CL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-98"
                     /label="GA0070216_RS33480_Condensation_LCL.2"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1596"
                     /protein_start="1301"
                     /score="321.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVAADG"
                     /tool="antismash"
                     /translation="ARVPLSFAQRRLWFISRLEESTAAYHVPIVLRLDGVDPVALELAL
                     RDVLARHEVLRTVLPMVDGEPFQQIIPVDELDWRLTIAETDDQDAAVSAAIAEPFDLTA
                     EVPVRAWLFDGSVLVLVVHHVAADGWSMAPLARDLSQAYAARRVGQVPGWSPLPVQYAD
                     FAVWQRGLLGVESDVGSVGSRQVGFWRGVLAGVPQELRLPVDRVRPVVAGRGGCGVGLV
                     VSAGVHARVVEVARVEGVTVFMVLQAALAVLLSRLGAGVDVPVGTVVAGRVDEALDEVV
                     GFFVNTLVLRTDVS"
     CDS_motif       3934..3963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0016"
                     /evalue="1.30E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1316"
                     /protein_start="1306"
                     /score="8.4"
                     /tool="antismash"
                     /translation="SFAQRRLWFI"
     CDS_motif       3985..4095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0017"
                     /evalue="2.20E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1360"
                     /protein_start="1323"
                     /score="45.8"
                     /tool="antismash"
                     /translation="AAYHVPIVLRLDGVDPVALELALRDVLARHEVLRTVL"
     CDS_motif       4282..4347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0018"
                     /evalue="4.70E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1444"
                     /protein_start="1422"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VHHVAADGWSMAPLARDLSQAY"
     CDS_motif       4396..4431
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0019"
                     /evalue="6.40E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1472"
                     /protein_start="1460"
                     /score="18.6"
                     /tool="antismash"
                     /translation="QYADFAVWQRGL"
     CDS_motif       4702..4791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0020"
                     /evalue="5.50E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1592"
                     /protein_start="1562"
                     /score="38.1"
                     /tool="antismash"
                     /translation="DVPVGTVVAGRVDEALDEVVGFFVNTLVLR"
     CDS_motif       4852..>4922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33480_0021"
                     /evalue="2.10E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="GA0070216_RS33480"
                     /protein_end="1636"
                     /protein_start="1612"
                     /score="42.6"
                     /tool="antismash"
                     /translation="LSAFEHQDVPFERLVEELAPERSL"
ORIGIN
        1 acgccgatcc gtaacgtgcg cgcgttcgtg ctcgacgaca ggttgaagcc ggtgccggtc
       61 ggggtggcgg gtgagttgta tgtcgcgggt gcggcgttgg cgcggggtta tgtgggccag
      121 gcgggtctga ccgcggagcg gtttgtgggt tgtccgttcg ggtcgggtga gcggatgtat
      181 cggaccgggg accgggtgcg gcatcttccg gatgggcggt tggtgttcct cggccgggtc
      241 gatgatcagg tgaagatccg cgggtatcgg gtcgagccgg gcgagatcca caccgtgctg
      301 gtcgcgcacc ccgacgtacg ccaggcggcc gtgctcctcc gggacgaccg gctggtggcg
      361 tacgtggtcg gaggcgacgg cagcgggctg cgggagtggg tggcacagcg gctgcccgag
      421 cacatggtgc catcgaccgt cgttgtcctc gacgcgctgc cgctgacctc gaacggcaag
      481 ctggaccgct ccgcgctgcc caccccggac cggaccgcgc ccgccggcgt cgaccgcgac
      541 tcgctcgacc cacgtacgga gctgctccgc gtcgcgttcg ccgacgtgct cggcctcgac
      601 cacgtcggtg tcgacgacga cttcttcgac ctgggaggac actcgctgct cgcggtccgg
      661 ctgatcagcc ggatccggat ggtgttccac gccgacgtgc gactccgtac cctgttcgac
      721 gctcccacgc cggcccggct cgcggcccgg ctgtccgacg ccgaccaggc caggctcgcg
      781 ctcggcgtgc agatccggcc ggagcggatg ccgctgtcgt acgcgcagcg ccgcctgtgg
      841 ttcatcaacc agctcgaagg cccatcggtc acctacacca tgcctgtggt tctccggctg
      901 tccggcgacg tggacccggc ggcccttgac gcggcgctgc gcgacgtgat cacccgacac
      961 gaggtgctgc gtaccgtgtt cgcgacggtg gacggcgagc cgtaccagcg ggtggtcgac
     1021 ccgacggatc tggactggtc gctggaactc gccacgggcg agtcggacgc gatcgccgcc
     1081 gccaccggtt accgcttcaa cctcgcgcag gagatcccga tccgggcctg gctgttcgac
     1141 cagcagacgc ttgtggtggt cgtccatcac atcgccggtg acggatggtc ctgggagccg
     1201 ctggcccggg acctgtccac cgcctacgcg gcccgccgtg ccggcagccc cccggactgg
     1261 cgtccgctgc ccgtgcagta cgccgactac gcactgtggc agcgggagct gctcggcgat
     1321 ccagacaacc cggacagcgt cgcgggccgg cagctgacct actggcggga tcggctcgcc
     1381 gacgtacccg aggaactgaa cctgccggtc gaccgaccgc gcccggccac cgccggccac
     1441 gagggccaca gcatcgacct gaccgtgccc gccgcggtgc acgtccggct gcgcgcgctt
     1501 gcccgcgccg agggtgtgac cgtgccgatg gtggttcagg cagccctcgc ggtcctgctg
     1561 tcccgtctcg gcgccggcac cgacgttccg atcggctcgg tcgtcgccgg ccggaccgac
     1621 gaggcgctcg atgacctggt cggcttcttc gtgaacacgc tcgtgctgcg gaccgacctg
     1681 tccggcgacc cggccttcac cgaactcctc gctcgggtcc gggataccgc cgtggcagcc
     1741 ctggagcacc aggacgttcc cttcgaccgc ctcgtggagg aactcgcgcc ggctcggtca
     1801 ctgtcgcggc acccgctgtt ccaggtggcg ctgaacgtgc agaaccaggt cgaagcgagc
     1861 ctggacatcg tcggcgccga cgcgtaccgg ttgtccgcgg gcactcgggc gatccggttc
     1921 gacctcgagt tcagcttgcg cgaaacgttg aacgcggacg gcgcgccact cgggctgcgc
     1981 ggtgtcgtgc gggggtccgc tgacctgttc gaggccgaca ccgtgcggcg gctcgtcgac
     2041 cggttcgtac gggtcctggg cacggtcgcc gccgagccgg gcacccggtt gagcgctgtc
     2101 atcctgctcg acgacgccga gcgacatgac gtgctcaccg gttggaatgc caccggcgcg
     2161 cggatcgacc cgacgtcggt cccggccctg atcgccgccc aggtcgcggc cacgccggac
     2221 gctccggcag tccacttcgg cggagcgctc ctctcgtacg ccgacctggg tgcacgtgct
     2281 gaccggctgg ctcgggtgct ggtggcacac ggcgtcggac cggagacggt cgtcgcgctg
     2341 cgcctgccgc gcggcttcga catgatcgtc gcgctgttgg ccgtgtggcg ggctggcggc
     2401 gcgtacctgc cgatcgaccc ggagacgccg accgagcggc tggcgtacgt ggtggaggac
     2461 gcccagccgg tggccatcgt cgccaccccg gcgaccgccg gggcggtgcc cgccggaccg
     2521 cacctgatcc tcatcgacgc gctgccggac gacgccgacg acgtgtcact tccggagtgg
     2581 ggacacggcg gccaggccgc ttacgtcatc ttcacctccg gctcgaccgg ccgaccgaag
     2641 ggggtgctgg tcgaccacga cgcgctgacc aacttcgtgt ccgccatcgc cgatcacctg
     2701 gagatcactc ccggcacggc gatgctgcag tacgcgtcgt tctccttcga catgtcggtg
     2761 atggacatcg tcgtgccgct cagccgcggt gggaccgtgg tcgtgccgag tgaggccgag
     2821 cgtgccgagc ccgagctgct acgggcgctc gtcgcggcgt ccggggcacg gacggcgacg
     2881 ctggtgcctt cgctgctcgg cgtgctcgaa ccggacgacc tcgccggcgt gcgggtgctg
     2941 ttcgtcggcg gcgaggtcgt cgacccggcg ctggcggccc ggtgggcgcc gggccgcaag
     3001 ctggtccaca tgtacgggcc gaccgagacg acgatcgtga tggcggtgga cgcgatcgac
     3061 ccgcagcgtc cgggcccgct accgctgggc gggccgctgg ccaacagccg cgtcttcgtc
     3121 ctcgaccacg cgttggcgcc ggtgccggtg ggtgtggtcg gtgagctgta catcgccggg
     3181 tcccagctgg cgcggggtta cgttggacgg gccgcgctga cctccgagcg gttcgtggca
     3241 tgtcctttcg gggcgggcga gcggatgtac cgcaccggtg acctggtgcg gtggaacgcc
     3301 gacggtgagc tggtgttcgc gggtcgggcg gatgaccagg tgaagatccg ggggttccgg
     3361 atcgagctgg gcgaggtgca ggctgcgctg acggcacatc cggcagttca ccaggcggtc
     3421 gtggtggttc gggaggacag cccgggcgag cgacggctgg tcggatacgt gaccggcggt
     3481 gcggacctcg acatcgaggc tgtacagggt ttcgtggcgg cgcggttgcc ggagtacatg
     3541 gtgccaacgc ttgtggtgtt ggccgggatg ccgttgacgt cgagcgggaa ggtggaccgt
     3601 cgagcactgc cggtcccggt ggtggtggaa cgccgtcccg gttccggtcg gggtgcgatg
     3661 acgcctcacg aggaattgtt gtgtgcggca ttcgccgcgg tgctgggccg tgacgccgtg
     3721 ggcgtggatg aggacttctt cgccctgggc gggcactcgc tgatggcggt acggctcgcc
     3781 ggccgggtac ggacggtgct gggcgtcgag gtgcccctgc ggacgttgtt cgaagcgccg
     3841 acgccacggg cgttggcggt gcggctgtcg tccgcggaag accaggcccg tccggctctg
     3901 acgtcggtcg aacggccagc gcgggtgccg ctgtccttcg cacaacgcag gttgtggttc
     3961 atcagccggt tggaggagtc gacggcggcg tatcacgtgc cgatcgtgct gcgcctcgac
     4021 ggggtcgacc cggtggcgct ggagttggcg ctgcgggatg tgttggcccg gcacgaggtg
     4081 ttgcgcacgg tgttgccgat ggtcgacgga gagccgttcc aacagatcat tcccgtcgac
     4141 gagctggact ggcggttgac gatcgccgag accgatgacc aggacgccgc cgtgtcggcg
     4201 gcgatcgcgg agccgttcga cctcaccgcc gaggtgccgg tccgggcgtg gttgttcgac
     4261 gggtcggtac tggtgcttgt ggtgcatcac gtggcggccg acggctggtc gatggccccg
     4321 ttggcgcggg atctgtcgca ggcgtacgcg gctcgtcggg tgggtcaggt gccggggtgg
     4381 tcgccgttgc cggtgcagta tgcggatttt gcggtgtggc agcgggggtt gttgggtgtg
     4441 gagtcggatg tggggagtgt gggttcgcgg caggtggggt tttggcgtgg ggtgttggcg
     4501 ggtgtgccgc aggagttgcg gttgccggtg gatcgggtgc gtccggtggt ggctggtcgt
     4561 gggggttgtg gggtggggtt ggtggtgtcg gcgggggtgc atgcgcgggt ggtggaggtg
     4621 gcgcgggttg agggggtgac ggtgttcatg gtgttgcagg cggcgttggc ggtgttgttg
     4681 tcgcggttgg gtgcgggggt ggatgtgccg gtggggacgg tggtggcggg tcgtgtggat
     4741 gaggcgttgg atgaggtggt ggggtttttt gtgaatacgt tggtgttgcg gacggatgtg
     4801 tcgggtgatc cgtcgtttgt ggagttgttg gggcgggttc gtgaggtggg gttgtcggcg
     4861 ttcgagcatc aggatgtgcc gttcgagcgg ttggtggagg agttggcgcc ggagcgttcg
     4921 ct
//
