LOCUS       NZ_FMCU01000050         4996 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000050
VERSION     NZ_FMCU01000050.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 4996
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000050.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..4996
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:4984](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..4984)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(<1..4984)
                     /locus_tag="GA0070216_RS33475"
                     /old_locus_tag="GA0070216_1501"
     CDS             complement(<1..4984)
                     /NRPS_PKS="Domain: PKS_AT (0-271). E-value: 1.7e-94. Score:
                     308.5. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33475_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (553-726). E-value: 6.8e-56.
                     Score: 181.0. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33475_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (826-899). E-value: 1.5e-31. Score:
                     100.5. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33475_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (920-1344). E-value:
                     5e-186. Score: 610.6. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33475_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1466-1660). E-value: 1.9e-73.
                     Score: 239.3. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33475_PKS_AT.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="GA0070216_RS33475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1501"
                     /product="type I polyketide synthase"
                     /protein_id="WP_245722906.1"
                     /sec_met_domain="PKS_AT (E-value: 2.8e-96, bitscore: 308.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6e-57, bitscore:
                     178.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 4.1e-229, bitscore:
                     746.6, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.9e-96, bitscore:
                     308.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRELAAAFPVFASALDEVCAAFGPLLGGDLREVVFADPDGVLDQ
                     TGWTQPALFAVEVALFRLAQSWGLKPDFVAGHSIGELAAAHVAGVWSLEDACRVVAARG
                     GLMQALPAGGAMLAIAAPLAELDLGDVDVAAVNGPRAVVVSGTEEQIAALEARLEVKTR
                     RLRVSHAFHSHLMDPMLAEYGRVLDGVTANSAVVPLVSTATGGLATDAELGSAEYWQGQ
                     VRGTVRFADAVAALAARGVTRFVEIGPDSVLTAMVGECVEDTAAIPLQRRDRDQVTGYA
                     AGMAQAWVTGADLDWAGVHPDARQVALPTYAFARQRYWLETPTAAPATATDGWRYRVVW
                     RATDLPTGPELTGDWWIVTPDALTDDPRVTAAADALAARGATVIRRTASEVTGPDRDTE
                     GSGDAAGSVGGDTPAGVVSLLALDDTPDPYDAGLSVGVTGTVRLVHALAAAGFTGRLWC
                     LTTGGVAVDRYEDLPHAAQAGLWGLGTVLSLDYPGWWGGLVDLPTEWTPDNLDRLVDVL
                     ADGGEDQVAVRTAGVLARRMVRWPAAGSPDRRWRPRGTVLVTGGTGGIGAHLTEWLLDQ
                     GAERVVLASRRGPAAPGAADLAARLPGVQVVACDVADRDAVAALLDGIGDDLTAVFHAA
                     GVLYDPAPLDATSLDDFAAVCRAKVRGATHLDALLADRPLDAFVLFASGAAVWGSAGQA
                     AYGTGNAWLDALAHQRRRRGRTATSIAWGTWGGGGMVDEQATEHLLRQGTPPMAPRLAL
                     GALQQVLDHDESHLVVTDIDWARFTPIYTLARPRPLLAALPEAHQSAVTVAPATPADTS
                     VLAGLPDAERLPYLLDTVRAQVAAVLGYDAATTVDVQRPFRELGFDSLTAVELRNALGA
                     AVGLRLPATMVYDHPTPAVLARHLYDELVGTTAPTNVTSGGGGSDPDEPIAIVGMSCRY
                     PGGVRSPEDLWRLVDSGTDAISAFPVDRGWDTDALFDADPDRPGTSYVRSGGFVYEAGA
                     FDAEFFGISPREAIAMDPQQRLMLEVTWEACERAGMNPEALRGSPVGVFVGSGAQDYGD
                     LLGLAPAESEAYLSTGSSASVISGRVSYAFGFEGPSMTIDTACSSSLVALHLAAQALRA
                     GECDSAIAGGVLVMSNPTPFVAFSRQRGLAPDGRCKSFSDDADGTGWSEGVGVLVLERL
                     SDAQRRGHRVYGVIRGSAVNQDGASNGLTAPNGPAQQRVIRAALANARLTPDQVDAVEA
                     HGTGTTLGDPIEAQALLATYGRDRDRPLWLGSIKSNMGHAQAAAGMAGVIKMVMAMRHG
                     TLPRTLHAGTPSRQIDWAAGDVRLLTEPVAWPAGGRPRRAGVSSFGISGTNAHVIVEEA
                     PPVESAGPVEGAEPPVVLWPLSARSAAALAGQAARLHDELPTDVRPVDVGHALAAGRAA
                     LDHRGVVVGRPGTDPTAGRSASTDGTEPGADPSVPGGPDLTAGLAALAAGTGLSGRVSA
                     GRTAVLFTGQGAQRVGMGRELADAFPVFAAALDEVCAAFGPLLGGDLREVMFTDPDGVL
                     DQTGWTQPALFAVEVALFRLAESWGLKPDFVAGHSIGELAAAHVAGVWSLADACRVVAA
                     RGGLMQALPAGGAMLAIAAPLVELDLGDVDVAAVNGPRAVVVSGTEEQVAALEASLEVK
                     TRRLRVSHAFHSHLMDPMLADYG"
     source          1..4996
                     /db_xref="taxon:121616"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070216_150"
                     /organism="Micromonospora matsumotoense"
                     /strain="DSM 44100"
                     /type_material="type strain of Catellatospora
                     matsumotoense"
     region          1..4996
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..4996
                     /SMILES="CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     aSDomain        complement(5..586)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33475_PKS_AT.2"
                     /evalue="1.90E-73"
                     /label="GA0070216_RS33475_PKS_AT.2"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1660"
                     /protein_start="1466"
                     /score="239.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQRVGMGRELADAFPVFAAALDEVCAAFGPLLGGDLREV
                     MFTDPDGVLDQTGWTQPALFAVEVALFRLAESWGLKPDFVAGHSIGELAAAHVAGVWSL
                     ADACRVVAARGGLMQALPAGGAMLAIAAPLVELDLGDVDVAAVNGPRAVVVSGTEEQVA
                     ALEASLEVKTRRLRVSHAFHSHLMDPMLADY"
     aSModule        complement(5..2224)
                     /domains="nrpspksdomains_GA0070216_RS33475_PKS_KS.1"
                     /domains="nrpspksdomains_GA0070216_RS33475_PKS_AT.2"
                     /incomplete
                     /locus_tags="GA0070216_RS33475"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(35..61)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0015"
                     /evalue="3.00E-02"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1650"
                     /protein_start="1641"
                     /score="7.6"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       complement(116..154)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0014"
                     /evalue="4.00E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1623"
                     /protein_start="1610"
                     /score="13.6"
                     /tool="antismash"
                     /translation="AAVNGPRAVVVSG"
     CDS_motif       complement(230..352)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0013"
                     /evalue="9.20E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1585"
                     /protein_start="1544"
                     /score="69.3"
                     /tool="antismash"
                     /translation="GLKPDFVAGHSIGELAAAHVAGVWSLADACRVVAARGGLMQ"
     CDS_motif       complement(365..415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0012"
                     /evalue="8.80E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1540"
                     /protein_start="1523"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GWTQPALFAVEVALFRL"
     CDS_motif       complement(539..583)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0011"
                     /evalue="5.50E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1482"
                     /protein_start="1467"
                     /score="15.8"
                     /tool="antismash"
                     /translation="FTGQGAQRVGMGREL"
     aSDomain        complement(953..2224)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33475_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.00E-186"
                     /label="GA0070216_RS33475_PKS_KS.1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1344"
                     /protein_start="920"
                     /score="610.6"
                     /tool="antismash"
                     /translation="IAIVGMSCRYPGGVRSPEDLWRLVDSGTDAISAFPVDRGWDTDAL
                     FDADPDRPGTSYVRSGGFVYEAGAFDAEFFGISPREAIAMDPQQRLMLEVTWEACERAG
                     MNPEALRGSPVGVFVGSGAQDYGDLLGLAPAESEAYLSTGSSASVISGRVSYAFGFEGP
                     SMTIDTACSSSLVALHLAAQALRAGECDSAIAGGVLVMSNPTPFVAFSRQRGLAPDGRC
                     KSFSDDADGTGWSEGVGVLVLERLSDAQRRGHRVYGVIRGSAVNQDGASNGLTAPNGPA
                     QQRVIRAALANARLTPDQVDAVEAHGTGTTLGDPIEAQALLATYGRDRDRPLWLGSIKS
                     NMGHAQAAAGMAGVIKMVMAMRHGTLPRTLHAGTPSRQIDWAAGDVRLLTEPVAWPAGG
                     RPRRAGVSSFGISGTNAHVIVEEAP"
     CDS_motif       complement(1175..1219)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0010"
                     /evalue="3.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1270"
                     /protein_start="1255"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GSIKSNMGHAQAAAG"
     CDS_motif       complement(1274..1318)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0009"
                     /evalue="4.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1237"
                     /protein_start="1222"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(1694..1741)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0008"
                     /evalue="1.90E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1097"
                     /protein_start="1081"
                     /score="22.8"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     CDS_motif       complement(1847..1876)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0007"
                     /evalue="3.80E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="1046"
                     /protein_start="1036"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="VFVGSGAQDY"
     aSDomain        complement(2288..2506)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33475_ACP.1"
                     /evalue="1.50E-31"
                     /label="GA0070216_RS33475_ACP.1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="899"
                     /protein_start="826"
                     /score="100.5"
                     /tool="antismash"
                     /translation="LDTVRAQVAAVLGYDAATTVDVQRPFRELGFDSLTAVELRNALGA
                     AVGLRLPATMVYDHPTPAVLARHLYDEL"
     aSModule        complement(2288..4984)
                     /complete
                     /domains="nrpspksdomains_GA0070216_RS33475_PKS_AT.1"
                     /domains="nrpspksdomains_GA0070216_RS33475_PKS_KR.1"
                     /domains="nrpspksdomains_GA0070216_RS33475_ACP.1"
                     /locus_tags="GA0070216_RS33475"
                     /monomer_pairings="mal -> ohmal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(2807..3325)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33475_PKS_KR.1"
                     /evalue="6.80E-56"
                     /label="GA0070216_RS33475_PKS_KR.1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="726"
                     /protein_start="553"
                     /score="181.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLVTGGTGGIGAHLTEWLLDQGAERVVLASRRGPAAPGAADLA
                     ARLPGVQVVACDVADRDAVAALLDGIGDDLTAVFHAAGVLYDPAPLDATSLDDFAAVCR
                     AKVRGATHLDALLADRPLDAFVLFASGAAVWGSAGQAAYGTGNAWLDALAHQRRRRGRT
                     ATSIAWGTWG"
     CDS_motif       complement(2852..2962)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0006"
                     /evalue="4.90E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="711"
                     /protein_start="674"
                     /score="57.7"
                     /tool="antismash"
                     /translation="LDAFVLFASGAAVWGSAGQAAYGTGNAWLDALAHQRR"
     CDS_motif       complement(3224..3322)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0005"
                     /evalue="5.10E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="587"
                     /protein_start="554"
                     /score="44.8"
                     /tool="antismash"
                     /translation="TVLVTGGTGGIGAHLTEWLLDQGAERVVLASRR"
     aSDomain        complement(4172..4984)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33475_PKS_AT.1"
                     /evalue="1.70E-94"
                     /label="GA0070216_RS33475_PKS_AT.1"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="271"
                     /protein_start="0"
                     /score="308.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MGRELAAAFPVFASALDEVCAAFGPLLGGDLREVVFADPDGVLDQ
                     TGWTQPALFAVEVALFRLAQSWGLKPDFVAGHSIGELAAAHVAGVWSLEDACRVVAARG
                     GLMQALPAGGAMLAIAAPLAELDLGDVDVAAVNGPRAVVVSGTEEQIAALEARLEVKTR
                     RLRVSHAFHSHLMDPMLAEYGRVLDGVTANSAVVPLVSTATGGLATDAELGSAEYWQGQ
                     VRGTVRFADAVAALAARGVTRFVEIGPDSVLTAMVGECVEDTAAIPLQR"
     CDS_motif       complement(4466..4492)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0004"
                     /evalue="3.00E-02"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="173"
                     /protein_start="164"
                     /score="7.6"
                     /tool="antismash"
                     /translation="LRVSHAFHS"
     CDS_motif       complement(4547..4585)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0003"
                     /evalue="4.00E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="146"
                     /protein_start="133"
                     /score="13.6"
                     /tool="antismash"
                     /translation="AAVNGPRAVVVSG"
     CDS_motif       complement(4661..4783)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0002"
                     /evalue="1.20E-23"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="108"
                     /protein_start="67"
                     /score="75.4"
                     /tool="antismash"
                     /translation="GLKPDFVAGHSIGELAAAHVAGVWSLEDACRVVAARGGLMQ"
     CDS_motif       complement(4790..4846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33475_0001"
                     /evalue="6.30E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="GA0070216_RS33475"
                     /protein_end="65"
                     /protein_start="46"
                     /score="13.0"
                     /tool="antismash"
                     /translation="GWTQPALFAVEVALFRLAQ"
ORIGIN
        1 gcccgtagtc ggccagcatc gggtccatca ggtgcgagtg gaacgcgtgc gacacccgca
       61 accggcgcgt cttcacctca agcgacgcct ccaacgcggc aacctgctcc tcggtgccag
      121 agacgacgac ggcccgggga ccgttcaccg ccgccacgtc cacgtcaccg agatccaact
      181 cgacaagcgg cgcggcgatc gccagcatcg cgccgcccgc cggcagggcc tgcatcagcc
      241 cgccccgggc cgccacgaca cggcaggcgt ccgccaggga ccacaccccg gcgacgtgcg
      301 ccgcagccaa ctcaccgatc gaatgacccg ccacgaaatc cggcttgaga ccccacgact
      361 cggccaggcg gaacaacgcc acctcgaccg cgaacaacgc cggctgcgtc caccccgtct
      421 gatccagaac cccatccgga tcggtgaaca tcacctcccg cagatcacca cccagcaacg
      481 gcccgaacgc cgcacacacc tcgtccagag cggcggcgaa caccgggaac gcgtccgcca
      541 actcacgacc catccccacc cgctgcgcac cctgaccggt gaacagcacc gccgtacgac
      601 cggcgctgac ccggcccgag agtccggtgc cggctgccag agccgccagg ccggcggtca
      661 ggtcggggcc gcccgggacc gacgggtccg cgcccggctc ggtgccgtcg gtcgaggccg
      721 accgcccggc ggtcgggtcg gtgccgggtc ggccgacgac cacgccccgg tggtccaggg
      781 cggcccggcc ggcggccagc gcgtgcccga cgtccaccgg ccgtacgtcg gtggggagtt
      841 cgtcgtggag ccgggcggcc tgcccggcca gcgcggcggc ggaccgggcg gacagcggcc
      901 agagcaccac cggcggctcg gcgccctcga ccggcccggc ggactcgacc ggtggggctt
      961 cctcgacgat cacgtgcgcg ttggtgccgc tgatcccgaa cgacgacacc ccggcccggc
     1021 ggggccggcc cccggccggc caggcgaccg gctcggtgag cagccggacg tcgccggccg
     1081 cccagtcgat ctgtcgggac ggggtcccgg cgtgcagggt gcgcggcagc gtcccgtgcc
     1141 gcatcgccat caccatcttg atcaccccgg ccatgccggc ggcggcctgg gcgtgcccca
     1201 tgttcgactt gatcgagccg agccacagcg ggcggtcccg gtcccggccg tacgtggcga
     1261 gcagcgcctg cgcctcgatc gggtcaccga gggtggtgcc ggtgccgtgt gcctcgacgg
     1321 cgtcgacctg gtcgggggtg agccgggcgt tggccaacgc cgcccggatc acccgctgct
     1381 gggccggccc gttcggcgcg gtcaacccgt tggacgcccc gtcctggttc accgccgaac
     1441 cccggatcac cccgtagacg cggtgaccgc gccgctgggc gtcggagagc cgctccagca
     1501 ccagcacgcc gaccccctcg gaccagccgg tgccgtcggc gtcgtcggag aacgacttgc
     1561 agcggccgtc cggggcgagg ccccgctgcc ggctgaacgc cacgaacggg gtggggttcg
     1621 acatcaccag caccccgccg gcgatggcgc tgtcgcactc cccggcccgc agcgcctggg
     1681 cggcgaggtg cagcgcgacc agcgacgacg aacacgccgt gtcgatcgtc atcgacggcc
     1741 cctcgaaccc gaacgcgtac gacacccgac cggagatcac cgaggcggaa ctgccggtgc
     1801 tcaggtacgc ctccgactcg gcgggggcga gaccgagcag gtcgccgtag tcctgggcac
     1861 cggagccgac gaagaccccg accgggctgc cgcgcagcgc ctcggggttc attccggccc
     1921 gctcgcacgc ctcccaggtg acctccagca tcaaccgctg ctgcgggtcc atggcgatcg
     1981 cctcgcgggg cgagatgccg aagaactcgg cgtcgaacgc gcccgcctcg tagacgaagc
     2041 cgccggaacg gacgtagctg gtgccgggcc ggtccgggtc ggcgtcgaag agcgcgtcgg
     2101 tgtcccagcc ccggtcgacg gggaacgcgc tgatcgcgtc ggtgccgctg tcgaccagcc
     2161 gccacaggtc ctccggggac cggacgcccc ccgggtagcg gcagctcatc ccgacgatgg
     2221 cgatcggctc gtcggggtcg gacccgccgc cgccggaggt cacgttggtc ggggcggtgg
     2281 tgccgacgag ttcgtcgtac aggtggcggg ccagcacggc gggggtcggg tggtcgtaga
     2341 ccatggtggc cggcagccgc agcccgacgg ccgcgccgag ggcgttacgc agctccaccg
     2401 cggtcagcga gtcgaagccg agttcccgga acggccgctg gacgtccacg gtggtggccg
     2461 cgtcgtaccc gaggacggcg gcgacctgcg cgcggacggt gtccagcagg tacggcagcc
     2521 gctcggcgtc gggcaggccg gccagcacgg aggtgtcggc gggcgtggcc ggggcgacgg
     2581 tcaccgcgct ctggtgggcc tcggggagcg cggcgagcag cggccggggc cgggccaggg
     2641 tgtagatcgg ggtgaaccgg gcccagtcga tgtcggtgac cacgaggtgg ctctcgtcgt
     2701 ggtcgagcac ctgctgcaac gcaccgaggg cgaggcgcgg cgccatcggc ggggtgccct
     2761 ggcgcaggag gtgttcggtg gcctgctcgt cgaccatgcc tccaccgccc caggtgcccc
     2821 aggcgatgga ggtggcggtc cgaccccggc ggcggcgctg gtgggcgagc gcgtcgagcc
     2881 aggcgttgcc ggtgccgtag gcggcctgcc cggcgctgcc ccagacggcc gccccggagg
     2941 cgaacaggac gaacgcgtcg agcggccggt cggcgagcag cgcgtcgagg tgggtcgcgc
     3001 cgcgcacctt ggcccggcac acggcggcga agtcgtcgag gctggtcgcg tcgagggggg
     3061 cggggtcgta gagcaccccg gcggcgtgga agacggcggt caggtcgtcg ccgatcccgt
     3121 cgagcagcgc ggcgaccgcg tcccggtcgg ccacgtcgca cgcgacgacc tgcacgccgg
     3181 gcaggcgggc ggccaggtcg gcggcgccgg gggcggccgg tccccgccgg ctggccagca
     3241 ccacccgctc ggcgccctgg tcgaggagcc attcggtgag gtgcgcgccg atgccgccgg
     3301 tgccgccggt gaccagcacg gtgccccggg gtcgccagcg ccggtcgggg ctgccggcgg
     3361 ccggccagcg gaccatccgc cgggccagca ccccggcggt acgcacggcg acctggtcct
     3421 caccgccgtc ggcgagcacg tcgacgagcc ggtcgaggtt gtcgggcgtc cactcggtcg
     3481 gcaggtcgac gaggccgccc caccagccgg ggtagtcgag ggagagcacg gtgccgaggc
     3541 cccagagccc ggcctgtgcg gcgtgcggca ggtcctcgta ccggtcgacg gcgacaccgc
     3601 cggtggtgag gcaccagagc cggccggtga acccggcggc ggcgagggcg tgcaccagtc
     3661 gtacggtgcc ggtgaccccg acggacagcc cggcgtcgta cgggtcgggg gtgtcgtcga
     3721 gggcgagcag cgagacgacc ccggccgggg tgtccccgcc gacggacccg gctgcgtcgc
     3781 cgctgccctc ggtgtcccgg tcgggtccgg tgacctcgct ggcggtacgt cggatgacgg
     3841 tggcaccacg ggcggcgagc gcgtcggcgg cggcggtgac ccgggggtcg tcggtgagcg
     3901 cgtccggcgt gacgatccac cagtccccgg tcagctccgg gccggtgggc aggtcggtgg
     3961 cccgccacac cacccggtac cgccagccgt cggtggcggt ggccggcgcg gcggtgggcg
     4021 tctccagcca gtaccgttgc cgggcgaagg cgtaggtggg cagggcgacc tggcgggcgt
     4081 cggggtgcac acccgcccag tccaggtccg ccccggtgac ccaggcctgg gccatcccgg
     4141 cggcgtagcc ggtgacctgg tcgcggtccc ggcgttgcaa cgggatcgcg gcggtgtcct
     4201 cgacacactc ccccaccatc gcggtgagca cgctgtccgg cccgatctcc acgaaccggg
     4261 tcacgccccg cgcggccagt gcggccaccg cgtcggcgaa ccgcacggtg ccgcgcacct
     4321 gcccctgcca atactccgcc gaacccagct cggcatcggt ggcaagacca ccggtcgccg
     4381 tcgacaccaa cgggacgacc gccgaattgg cggtgacccc gtcgaggacc cgcccgtact
     4441 cggccagcat cgggtccatc agatgcgaat ggaacgcgtg cgacacccgc aacctgcggg
     4501 tcttcacctc aagccgagcc tccagcgccg cgatctgctc ctcggtgccc gacaccacga
     4561 cggcccgggg accgttcacc gccgccacat cgacgtcgcc gagatccaac tccgccaacg
     4621 gcgcggcgat cgccaacatc gccccaccgg cgggcaacgc ctgcatcaac ccacccctgg
     4681 ccgccaccac ccgacacgca tcttcaagcg accacacccc cgccacatgc gccgcagcca
     4741 actcaccgat cgagtgaccc gccacgaaat ccggcttcaa accccacgac tgcgcgaggc
     4801 ggaacaacgc cacctcgacc gcgaacaacg ccggctgcgt ccaccccgtc tggtcgagaa
     4861 ccccgtccgg atcggcgaac accacctccc gcagatcacc accgagcaac ggcccgaacg
     4921 cggcacacac ctcgtccaac gccgacgcga acaccgggaa cgccgccgcc aactcacgac
     4981 ccatccccac ccgctg
//
