LOCUS       NZ_FMCU01000047         5462 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000047
VERSION     NZ_FMCU01000047.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 5462
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000047.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..5462
                     /db_xref="taxon:121616"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070216_147"
                     /organism="Micromonospora matsumotoense"
                     /strain="DSM 44100"
                     /type_material="type strain of Catellatospora
                     matsumotoense"
     gene            <1..>5462
                     /locus_tag="GA0070216_RS33450"
                     /old_locus_tag="GA0070216_1471"
     region          1..5462
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..5462
                     /SMILES="NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..5462
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:>5462](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..>5462
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             1..>5462
                     /NRPS_PKS="Domain: PCP (1-42). E-value: 4e-10. Score: 31.8.
                     Matches aSDomain: nrpspksdomains_GA0070216_RS33450_PCP.1"
                     /NRPS_PKS="Domain: Condensation_Dual (92-377). E-value:
                     2.1e-106. Score: 347.5. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33450_Condensation_Dual.1"
                     /NRPS_PKS="Domain: AMP-binding (536-933). E-value: 2e-95.
                     Score: 311.7. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33450_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1042-1109). E-value: 1.2e-24.
                     Score: 78.3. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33450_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1123-1424). E-value:
                     1.5e-112. Score: 367.4. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33450_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1595-1817). E-value:
                     1.1e-56. Score: 184.2. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33450_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="GA0070216_RS33450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1471"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_141723305.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-98, bitscore:
                     316.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.5e-18, bitscore:
                     52.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.3e-70, bitscore:
                     223.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFALGGHSLLVVRLVEWLRRRGIVVAVRAFFQTPTPAALAAATGV
                     RQARVPANRIPVGATRITPDMLPLVSLTQDEVDRIVAAVDGGAANIADVYPLAPLQEGL
                     LFHHLLAADGPDAYVLPTILRFVDRRLLDDFLAALQQVVDRHDIFRTGLVWAGLTEPVQ
                     AVLRHATLPVCEVVAAGPDDLLAAAGRTIDLSRAPLLDATVAPTTDGQWLALIRVHHVV
                     QDHTGLDVLLSEVRTILSGRADELPRPLPFRDFVAQARASGTEEEHERYFAALLGDVDE
                     STAAYGVLDVRGDGTDQRRAEEPLDPTLTERLRRVARELGTSPATILHTAWARTLAVLS
                     GREDVVFGTVLFGRMNAGSGSDRVPGPFINTLPVRLDTRRLTARAAVAAMRDQLAGLLE
                     HEHAPLAVAQRVSGVPADQPLFTTIFNYRHNISGTEIGIDGVTVVSSREFDNFPLSVSV
                     DDDADRIAFAVDAAGVIDPSAVGALLHTATEGLIGALESATDIPLAAVEVLPDDERHRM
                     LVDWNDTALPVAGTSLPEVFAAQVAATPEATAVVCDGVALSFAELDGRANRLTRLLVDR
                     GLVLESLVGLLLPRGVDALVAILAVLKAGGGYLPLDQEYPAERIALMVNDAAPAVVLAV
                     RETADLAPDGVPVLVLDDPAVEAEWASAPSDDLSVPVGPESVAYVIYTSGSTGRPKGVV
                     VTHGGLRNLYAFHRSGVMAGVEGHRLRFALTASLSFDTSWEGLLWMVAGHELHVISDEV
                     RRDTSAMVRYVAELGVGVMDVTPTYAEQLVADGLLDAPPDILLLGGEAVGPRLWEQLRD
                     ATGMWFVPLYGPTEYSVDALGLPTGDSAGPLVGVPIANTRAYVLDGGLRPVPVGVAGEL
                     YLAGVGVARGYLGQPGLSGSRFVACPFGGVGERMYRTGDVVRWDAAGRLEFLGRADGQV
                     KIRGFRIELGEVQAAVVAHQEIVRAAVVVHTDPAGDRRLVAYVVADDGDAELPERVRRF
                     VAERLPGHMVPAAVVVLDDLPVTVNGKLDERALPAPDFAARSGAGGAVADPRQELLCGV
                     FAEILGLPAVGVDDDFFALGGHSLLAVRLLGRLRNVLGTEVTLRALFDAPTPRAFVARL
                     TEAGPARLPLTAAARAERAPLSFAQRRLWFLDRLEGPNATYNLPEPLRLSGQVDVTALD
                     AALRDVLGRHEILRTVFDTVNGETGQRVIALDDLDWRLSAVEVGPEALDEAIAELAGQP
                     FDLAHEVPVRARLFSTASDEHVLLLVTHHIASDGWSIGRLAHDLSVAYAARCAGHAPTW
                     QPLPVQYADYALWQRELLGDERDPGSLLSTQVAYWRDALAGAPEELALPYDHARPAVSG
                     HGGHCATVEVPAVLHARLRELARAEGVTVSMVLQAAVAVLLSRLGAGTDIPIGTATAGR
                     TDEALDDLVGFFVNTVVLRTDLSGNPTLREVLAQLRESTLAGLGNQDVPFERLVEELAP
                     IRSLARHPLFQTMLTLQNNAVATLDLPGLRTEEYSVRSAVAKFDLEFSLAETFDDAGVP
                     AGLTGELVASADLFKPTSVVQLLRRFVRMLELLTDDAGQRVSAIDLLDAEERSQLLVDW
                     NDTAVSYPVDDTIVSLFARQVAVSPDAVAVVFEGVSVSYRELDVRAGAVARYLGSVGVG
                     PESVVGVCLPRGLDLVVALLGVLKAGGAYLPVDPEFPQARVEVLVRDAGALVVLESVVG
                     LDGPDVGSVGVGAAHPAYVLFTSGSMGRPKGVVVSHGGVVNRLRWMQDRFGLVVGERVV
                     QKTPFTFDVSVWEFFWPLVVGGTVVVARPGGHRDPAYLAELIREERVSTAHFVPSMLEA
                     FLPVAA"
     aSDomain        4..126
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_PCP.1"
                     /evalue="4.00E-10"
                     /label="GA0070216_RS33450_PCP.1"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="42"
                     /protein_start="1"
                     /score="31.8"
                     /tool="antismash"
                     /translation="FALGGHSLLVVRLVEWLRRRGIVVAVRAFFQTPTPAALAAA"
     aSDomain        277..1131
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_Condensation_D
                     ual.1"
                     /domain_subtypes="Condensation_Dual"
                     /evalue="2.10E-106"
                     /label="GA0070216_RS33450_Condensation_Dual.1"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="377"
                     /protein_start="92"
                     /score="347.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVVQDH"
                     /tool="antismash"
                     /translation="DVYPLAPLQEGLLFHHLLAADGPDAYVLPTILRFVDRRLLDDFLA
                     ALQQVVDRHDIFRTGLVWAGLTEPVQAVLRHATLPVCEVVAAGPDDLLAAAGRTIDLSR
                     APLLDATVAPTTDGQWLALIRVHHVVQDHTGLDVLLSEVRTILSGRADELPRPLPFRDF
                     VAQARASGTEEEHERYFAALLGDVDESTAAYGVLDVRGDGTDQRRAEEPLDPTLTERLR
                     RVARELGTSPATILHTAWARTLAVLSGREDVVFGTVLFGRMNAGSGSDRVPGPFINTLP
                     VRLD"
     aSModule        277..3327
                     /complete
                     /domains="nrpspksdomains_GA0070216_RS33450_Condensation_Dua
                     l.1"
                     /domains="nrpspksdomains_GA0070216_RS33450_AMP-binding.1"
                     /domains="nrpspksdomains_GA0070216_RS33450_PCP.2"
                     /locus_tags="GA0070216_RS33450"
                     /monomer_pairings="Orn -> Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       283..324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0001"
                     /evalue="1.10E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="108"
                     /protein_start="94"
                     /score="20.9"
                     /tool="antismash"
                     /translation="YPLAPLQEGLLFHH"
     CDS_motif       352..465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0002"
                     /evalue="3.50E-13"
                     /label="C2_dual_024-063"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="155"
                     /protein_start="117"
                     /score="42.1"
                     /tool="antismash"
                     /translation="YVLPTILRFVDRRLLDDFLAALQQVVDRHDIFRTGLVW"
     CDS_motif       655..717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0003"
                     /evalue="2.10E-05"
                     /label="C3_dual_135-156"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="239"
                     /protein_start="218"
                     /score="17.5"
                     /tool="antismash"
                     /translation="HHVVQDHTGLDVLLSEVRTIL"
     CDS_motif       751..783
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0004"
                     /evalue="2.40E-04"
                     /label="C4_dual_169-182"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="261"
                     /protein_start="250"
                     /score="13.9"
                     /tool="antismash"
                     /translation="PFRDFVAQARA"
     CDS_motif       1030..1125
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0005"
                     /evalue="1.40E-13"
                     /label="C5_dual_260-291"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="375"
                     /protein_start="343"
                     /score="43.1"
                     /tool="antismash"
                     /translation="DVVFGTVLFGRMNAGSGSDRVPGPFINTLPVR"
     CDS_motif       1180..1248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0006"
                     /evalue="1.10E-08"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="416"
                     /protein_start="393"
                     /score="27.6"
                     /tool="antismash"
                     /translation="LAGLLEHEHAPLAVAQRVSGVPA"
     aSDomain        1609..2799
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_AMP-binding.1"
                     /evalue="2.00E-95"
                     /label="GA0070216_RS33450_AMP-binding.1"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="933"
                     /protein_start="536"
                     /score="311.7"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FAAQVAATPEATAVVCDGVALSFAELDGRANRLTRLLVDRGLVLE
                     SLVGLLLPRGVDALVAILAVLKAGGGYLPLDQEYPAERIALMVNDAAPAVVLAVRETAD
                     LAPDGVPVLVLDDPAVEAEWASAPSDDLSVPVGPESVAYVIYTSGSTGRPKGVVVTHGG
                     LRNLYAFHRSGVMAGVEGHRLRFALTASLSFDTSWEGLLWMVAGHELHVISDEVRRDTS
                     AMVRYVAELGVGVMDVTPTYAEQLVADGLLDAPPDILLLGGEAVGPRLWEQLRDATGMW
                     FVPLYGPTEYSVDALGLPTGDSAGPLVGVPIANTRAYVLDGGLRPVPVGVAGELYLAGV
                     GVARGYLGQPGLSGSRFVACPFGGVGERMYRTGDVVRWDAAGRLEFLGRADGQVKIR"
     CDS_motif       1795..1836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0007"
                     /evalue="8.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="612"
                     /protein_start="598"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LAVLKAGGGYLPLD"
     CDS_motif       2032..2091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0008"
                     /evalue="5.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="697"
                     /protein_start="677"
                     /score="34.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVTH"
     CDS_motif       2590..2679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0009"
                     /evalue="6.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="893"
                     /protein_start="863"
                     /score="44.2"
                     /tool="antismash"
                     /translation="PVGVAGELYLAGVGVARGYLGQPGLSGSRF"
     CDS_motif       2764..2826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0010"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="942"
                     /protein_start="921"
                     /score="35.7"
                     /tool="antismash"
                     /translation="FLGRADGQVKIRGFRIELGEV"
     aSDomain        3127..3327
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_PCP.2"
                     /evalue="1.20E-24"
                     /label="GA0070216_RS33450_PCP.2"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1109"
                     /protein_start="1042"
                     /score="78.3"
                     /tool="antismash"
                     /translation="ELLCGVFAEILGLPAVGVDDDFFALGGHSLLAVRLLGRLRNVLGT
                     EVTLRALFDAPTPRAFVARLTE"
     CDS_motif       3349..3399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0011"
                     /evalue="6.30E-02"
                     /label="C67_dual_14fromHMM"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1133"
                     /protein_start="1116"
                     /score="6.4"
                     /tool="antismash"
                     /translation="LTAAARAERAPLSFAQR"
     aSDomain        3370..4272
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_Condensation_L
                     CL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-112"
                     /label="GA0070216_RS33450_Condensation_LCL.1"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1424"
                     /protein_start="1123"
                     /score="367.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIASDG"
                     /tool="antismash"
                     /translation="ERAPLSFAQRRLWFLDRLEGPNATYNLPEPLRLSGQVDVTALDAA
                     LRDVLGRHEILRTVFDTVNGETGQRVIALDDLDWRLSAVEVGPEALDEAIAELAGQPFD
                     LAHEVPVRARLFSTASDEHVLLLVTHHIASDGWSIGRLAHDLSVAYAARCAGHAPTWQP
                     LPVQYADYALWQRELLGDERDPGSLLSTQVAYWRDALAGAPEELALPYDHARPAVSGHG
                     GHCATVEVPAVLHARLRELARAEGVTVSMVLQAAVAVLLSRLGAGTDIPIGTATAGRTD
                     EALDDLVGFFVNTVVLRTDL"
     aSModule        3370..5451
                     /domains="nrpspksdomains_GA0070216_RS33450_Condensation_LCL
                     .1"
                     /domains="nrpspksdomains_GA0070216_RS33450_AMP-binding.2"
                     /incomplete
                     /locus_tags="GA0070216_RS33450"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3436..3549
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0012"
                     /evalue="1.20E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1183"
                     /protein_start="1145"
                     /score="49.8"
                     /tool="antismash"
                     /translation="ATYNLPEPLRLSGQVDVTALDAALRDVLGRHEILRTVF"
     CDS_motif       3757..3819
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0013"
                     /evalue="2.00E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1273"
                     /protein_start="1252"
                     /score="26.8"
                     /tool="antismash"
                     /translation="HHIASDGWSIGRLAHDLSVAY"
     CDS_motif       3868..3906
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0014"
                     /evalue="3.40E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1302"
                     /protein_start="1289"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       4174..4263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0015"
                     /evalue="2.10E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1421"
                     /protein_start="1391"
                     /score="42.6"
                     /tool="antismash"
                     /translation="DIPIGTATAGRTDEALDDLVGFFVNTVVLR"
     CDS_motif       4312..4431
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0016"
                     /evalue="1.90E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1477"
                     /protein_start="1437"
                     /score="58.8"
                     /tool="antismash"
                     /translation="RESTLAGLGNQDVPFERLVEELAPIRSLARHPLFQTMLTL"
     aSDomain        4786..5451
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33450_AMP-binding.2"
                     /evalue="1.10E-56"
                     /label="GA0070216_RS33450_AMP-binding.2"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1817"
                     /protein_start="1595"
                     /score="184.2"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FARQVAVSPDAVAVVFEGVSVSYRELDVRAGAVARYLGSVGVGPE
                     SVVGVCLPRGLDLVVALLGVLKAGGAYLPVDPEFPQARVEVLVRDAGALVVLESVVGLD
                     GPDVGSVGVGAAHPAYVLFTSGSMGRPKGVVVSHGGVVNRLRWMQDRFGLVVGERVVQK
                     TPFTFDVSVWEFFWPLVVGGTVVVARPGGHRDPAYLAELIREERVSTAHFVPSMLEAFL
                     "
     CDS_motif       4972..5013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0017"
                     /evalue="5.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1671"
                     /protein_start="1657"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPVD"
     CDS_motif       5140..5199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33450_0018"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070216_RS33450"
                     /protein_end="1733"
                     /protein_start="1713"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AYVLFTSGSMGRPKGVVVSH"
ORIGIN
        1 ttcttcgctc tgggtgggca ttcgttgttg gtggtgcggt tggtggagtg gctgcgtcgg
       61 cgggggatcg tggttgcggt ccgggcgttc ttccagactc cgacgcctgc tgctctggct
      121 gctgccacgg gtgtccggca ggcgcgggtg ccggcgaacc ggattccggt cggtgccacc
      181 cggatcaccc cggacatgct gccgctggtg tcgctgaccc aggacgaggt cgaccggatc
      241 gtggccgctg tcgacggcgg cgcggccaac atcgccgacg tctacccact cgccccccta
      301 caggaaggtc tgctcttcca ccacctgctg gccgccgacg ggcccgacgc ctacgtcctg
      361 cccaccatcc tgcgcttcgt cgaccgacgc ctgctcgacg acttcctggc cgcgttgcag
      421 caggtggtgg accggcacga catcttccgc accggcctgg tctgggcggg actgacggaa
      481 ccggtgcagg ccgtcctgcg gcacgcgacc ctacccgtat gcgaggtcgt ggcggccgga
      541 ccggatgacc tgctggccgc cgccgggcgg accatcgacc tgagccgcgc gccgctgctg
      601 gacgccacgg tggcccccac caccgacgga cagtggctgg ccctcatccg ggttcaccac
      661 gtcgtgcagg accacaccgg actcgacgta ctgctctccg aggtgcgcac gatcctgtcc
      721 ggccgggccg acgagttgcc ccggccgctg ccgtttcgcg acttcgtcgc ccaggcccgc
      781 gccagcggca ccgaggagga gcacgagcgg tacttcgccg ctctgctggg cgacgtcgac
      841 gagtcgaccg ccgcgtacgg ggtgctggac gtccgcggcg acggcaccga ccagcggcgg
      901 gccgaggaac cactcgatcc gaccctgacc gaaaggctgc ggcgggtcgc ccgtgagctc
      961 ggcaccagcc ctgcgacgat cctgcacacg gcctgggcac ggaccctcgc cgtgttgagc
     1021 ggccgggagg acgtcgtctt cggcaccgtg ctgttcggcc ggatgaacgc cggttccggg
     1081 tcggatcggg tgcccggccc gttcatcaac accctgccgg tgcgcctgga cacccgccgg
     1141 ttgaccgccc gggccgctgt tgccgcgatg cgcgaccagc tcgccgggct gctcgaacac
     1201 gaacacgccc cgctcgccgt cgcgcagcgg gtcagcggtg ttcccgccga ccagcccctg
     1261 ttcaccacga tcttcaacta ccggcacaac atctccggca ccgagatcgg tatcgacggc
     1321 gtcaccgtcg tctcgtcccg cgagttcgac aacttcccgc tgtcggtctc ggtcgacgac
     1381 gacgctgacc ggatcgcctt cgccgtagac gccgccggag tgatcgaccc gagcgccgtc
     1441 ggtgcgctgc tgcacaccgc caccgaaggg ctgatcggcg cgctcgaatc ggcgactgac
     1501 atcccgctgg ccgccgtgga ggtgctgccc gatgatgagc ggcaccggat gctcgtcgac
     1561 tggaatgaca cggcgctgcc ggttgcgggg acgtcgctgc cagaggtgtt cgcggcccag
     1621 gtcgcggcca cgccggaggc gacggcggtg gtctgcgacg gtgtcgcgct gagcttcgcc
     1681 gaactggacg ggcgggcgaa ccggcttacg cggctgctgg tcgaccgcgg gctcgtcctg
     1741 gagtcgctcg tgggtctgct gttgcctcgc ggggtggacg cgctggtggc gatcctggcg
     1801 gtgctgaagg ccggtggggg gtatctgccg ctcgaccagg agtatccggc cgagcggatc
     1861 gccctgatgg tgaacgacgc ggctccggcg gtggtgctgg cggtgcggga gaccgcggac
     1921 ttggccccgg acggtgtgcc ggtgctggtg ctcgacgatc cggctgtcga ggccgaatgg
     1981 gcgagcgcgc cgtcggatga cctttcggta cctgtcggtc cggagtcggt ggcgtacgtg
     2041 atctacacgt cgggctcgac gggccggccg aagggcgtgg tggtgaccca cggcgggttg
     2101 cgcaacctct acgccttcca ccggtccggg gtgatggcag gcgtcgaggg ccaccgactg
     2161 cggttcgcgt tgaccgcatc gttgtccttc gacacgtcct gggagggtct gctgtggatg
     2221 gtcgccggcc acgagctgca cgtgatctcc gacgaggtgc ggcgggacac ctcggcgatg
     2281 gtgcgatacg tggccgagct gggcgtcggg gtgatggacg tgacgccgac gtacgccgag
     2341 cagctggtgg ccgacggcct gttggacgcc ccgccggaca tcctgctgct cggtggtgag
     2401 gcggtcggac cccggctctg ggagcagctg cgcgacgcca cggggatgtg gttcgtgccc
     2461 ttgtacggtc ccaccgaata cagcgtggac gccctggggc tgccgaccgg tgacagcgcg
     2521 ggaccgctgg tcggggtgcc gatcgccaac acccgcgcct acgtcctcga cggtgggcta
     2581 cgaccggtac cggtcggggt ggccggtgag ctgtacctcg ccggcgtcgg ggtggcccgc
     2641 ggctacctgg ggcagccggg cctgtcgggg agccggttcg tggcgtgtcc gttcggtggc
     2701 gtcggcgagc ggatgtaccg cacgggcgac gtggtgcggt gggacgccgc aggacggttg
     2761 gagttcctgg gccgagccga cggccaggtc aagatccgcg gcttccggat cgagttgggg
     2821 gaggtgcagg ccgcggtcgt ggcccaccag gagatcgtgc gggccgcagt ggtggtacac
     2881 accgacccgg ccggtgaccg gcggctggtg gcctacgtgg tagccgacga cggggatgcc
     2941 gagctgccgg agcgggtccg gaggttcgtc gccgagcggc tgcccgggca catggtcccg
     3001 gcggcggtcg tggtcctcga cgacctgccg gtgacggtca acggcaagct cgacgagcgg
     3061 gcgttgcccg cccccgactt cgctgcccga agcggcgccg gcggggccgt ggccgatccc
     3121 cggcaggagt tgctgtgcgg cgtcttcgcc gagatactcg gcctgccggc ggtcggtgtc
     3181 gacgacgact tcttcgcgct cggcggacac tcgctgcttg ccgtacgcct gctcggtcgg
     3241 ctgcgcaacg tcctcggcac cgaggtgacg ctgcgggccc tcttcgacgc gccgactccc
     3301 cgcgcgttcg tcgcccggct gaccgaggcc ggcccggccc gtctgccgct gaccgccgcc
     3361 gcccgtgccg agcgggcacc actctccttc gcccagcgcc gactctggtt cctcgaccgg
     3421 ctggaaggcc ccaacgcgac ctacaacctg cccgagccgc tgcggctgtc cggacaggtc
     3481 gacgtcaccg cgctcgacgc cgccttgcgt gacgtcctcg gccggcacga gatcctgcgc
     3541 accgtcttcg acaccgtcaa cggtgagacc ggccagcggg tcatcgcgct ggacgacctc
     3601 gactggcgac tgagcgccgt cgaggtaggc ccggaggcgc tggacgaggc gatcgccgag
     3661 ctggccgggc aacccttcga cctcgcccac gaggtgccgg tccgggcccg gctgttctcg
     3721 accgcctccg acgagcacgt gctgcttctc gtgacgcacc acatcgccag tgacggctgg
     3781 tcgatcggcc ggctcgccca cgacctgtcg gtcgcgtacg ccgctcggtg tgccgggcac
     3841 gccccaacct ggcagccgct gccggtccag tacgccgact acgcgctgtg gcagcgcgag
     3901 ctgctcggcg acgagcggga cccgggcagc ctgctgtcca cccaggtcgc ctactggcgg
     3961 gacgcgctgg ccggcgctcc ggaagagctg gccctgccgt acgaccacgc ccgaccggcg
     4021 gtgtccggac acgggggcca ctgcgccacc gtcgaggtgc ccgccgtcct gcacgcccgg
     4081 ctccgcgagc tggcccgggc cgagggtgtg acggtctcga tggtgctgca ggccgctgtc
     4141 gccgtgttgc tgtcccgact cggagcgggc accgacatcc cgatcggaac ggcgaccgcc
     4201 ggtcgtaccg acgaggcgct ggacgacctg gtcggcttct tcgtcaacac ggtggtgctg
     4261 cgcaccgacc tgtccggcaa cccgaccctg cgcgaggtgc tggcccagct ccgggagagc
     4321 acgctggccg gtctcggtaa ccaggacgtg ccgttcgaga ggctggtcga ggagcttgct
     4381 ccgatccggt cgctggcccg ccacccgctg ttccagacga tgttgacgct acagaacaac
     4441 gccgtcgcga cgctggacct gccgggcctg cggaccgagg agtactcggt gcggagcgcc
     4501 gtggcgaagt tcgacctgga gttcagcctc gccgagacct tcgacgacgc gggcgtaccg
     4561 gccggcctga ccggagaact ggtcgcgtcg gctgaccttt tcaagcccac aagcgttgtc
     4621 caactgctgc gtcgtttcgt ccggatgctc gaactgctga cggacgatgc cgggcagcga
     4681 gtgagcgcca tcgacctgct ggacgcggag gagcgttccc agctgttggt ggactggaat
     4741 gacacggcgg tgtcgtatcc ggtggacgac accattgtgt cgttgttcgc ccgtcaggtg
     4801 gcggtgtcgc cggatgcggt ggcggtggtg tttgagggtg tgtcggtgtc gtatcgggag
     4861 ttggatgtgc gggctggtgc ggtggcgagg tatttggggt cggtgggggt ggggccggag
     4921 tcggtggtgg gggtgtgttt gccccgtggg ctcgacctgg tggtggcgtt gttgggggtg
     4981 ttgaaggctg gtggtgcgta tttgccggtt gatccggagt ttccgcaggc gcgggtggag
     5041 gtgttggtgc gtgacgcggg tgccctcgtc gtgttggagt cggtggtggg gttggacggt
     5101 ccggatgtgg ggtcggtggg ggtgggtgcg gcgcacccgg cgtatgtgtt gttcacgtcg
     5161 gggtcgatgg gtcggccgaa gggtgtggtg gtgtcgcatg ggggggtggt gaatcggttg
     5221 cggtggatgc aggatcggtt cgggttggtg gtgggtgagc gggtggtgca gaagacgccg
     5281 tttacgtttg acgtgtcggt gtgggagttc ttctggccgt tggtggtggg tgggacggtg
     5341 gtggtggccc gtccgggtgg tcatcgtgat ccggcgtatt tggcggagtt gattcgtgag
     5401 gagcgtgtgt cgacggcgca ttttgtgccg tcgatgttgg aggcgttcct gccggtggcc
     5461 gc
//
