LOCUS       NZ_FMCU01000040        20183 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000040
VERSION     NZ_FMCU01000040.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 20183
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20183
                     /db_xref="taxon:121616"
                     /mol_type="genomic DNA"
                     /note="contig: Ga0070216_140"
                     /organism="Micromonospora matsumotoense"
                     /strain="DSM 44100"
                     /type_material="type strain of Catellatospora
                     matsumotoense"
     region          1..20183
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..20183
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20183
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11766:15161](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(11767..15161)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            81..383
                     /locus_tag="GA0070216_RS33170"
                     /old_locus_tag="GA0070216_1401"
     CDS             81..383
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="GA0070216_RS33170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1401"
                     /product="transposase"
                     /protein_id="WP_176738962.1"
                     /transl_table=11
                     /translation="MGKKRPRPRRSFTAQFKAEIVELCQRGDRTIRQVSDDFDLTETAV
                     RDWVKQAELDTGTRSDGLSSDEKAELAQLRRENRRLREDVDILKRATAFFAKETR"
     gene            380..1276
                     /locus_tag="GA0070216_RS33175"
                     /old_locus_tag="GA0070216_1402"
     CDS             380..1276
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="GA0070216_RS33175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1402"
                     /product="IS3 family transposase"
                     /protein_id="WP_091245182.1"
                     /transl_table=11
                     /translation="MNVYPFIEAEKAGKHNVTRACELMKVSRSAYYQHATGQQSQRDLT
                     DQALTAKIIEVHAMSKGTYGAPRVHAELTDAGLRHGRKRIARLMRDVGVRGKSPRRWQT
                     TTITDPAAADRADLIGRDFTTDPARIDTRWCGDITYINTWQGWLYLATVIDLASRRVVG
                     WAVADHLKTDLIDAALNDAIVRRRPPSGLIFHSDRGCQYTSAQHARLAATHSIRLSNSR
                     RGQCWDNAVAESFFATVKTELLHRQPWPTHTAARQATFEYIEGWYNTRRRHSSLGYLSP
                     AAYEATRHTIQPVHQAA"
     gene            1689..2279
                     /locus_tag="GA0070216_RS35975"
     CDS             1689..2279
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS35975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245722894.1"
                     /transl_table=11
                     /translation="MNHVRRYDGIGPTLLDGRQVAIVAHLLRAEGPSAAALLAATKIEA
                     PWEQAVHGLLKTWQELAVGTVAVDHAELIDRVSAVPRTPGLAVFRVRLGLTALDLSTGL
                     PTDVVDNLTKQLVADATHDEDANAARDLINHPAVTAEHQGTLRPLMKASGLDQGYLPAT
                     ANDPLSVALDLAGAVIAMRRDRGRGAGLHARTQ"
     misc_feature    2151..2153
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2293..2307
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    3530..3548
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(3531..3549)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.53"
                     /tool="antismash"
     misc_feature    3549..3563
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.41"
                     /tool="antismash"
     gene            3926..4051
                     /locus_tag="GA0070216_RS36325"
     CDS             3926..4051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016815045.1"
                     /locus_tag="GA0070216_RS36325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_281190488.1"
                     /transl_table=11
                     /translation="MRFDVTVLDGEAGRRPAVLQAEAILDVLTWLHDQQHHAEPV"
     gene            4222..4377
                     /locus_tag="GA0070216_RS34925"
                     /old_locus_tag="GA0070216_1403"
     CDS             4222..4377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016815046.1"
                     /locus_tag="GA0070216_RS34925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1403"
                     /product="hypothetical protein"
                     /protein_id="WP_176739270.1"
                     /transl_table=11
                     /translation="MYATVGHDDTGSIVVYGPHDTPAIAPNDGAVTVAICPAGAADGTT
                     GTLAEV"
     gene            4395..4871
                     /locus_tag="GA0070216_RS33195"
                     /old_locus_tag="GA0070216_1404"
     CDS             4395..4871
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583812.1"
                     /locus_tag="GA0070216_RS33195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1404"
                     /product="hypothetical protein"
                     /protein_id="WP_245722895.1"
                     /transl_table=11
                     /translation="MLPRVAFYGRTAEARDLATAARVVGGQYQQCVSVLPDGAITAVFS
                     DLGTRPDYRRAPANLFLDHEREISRDGGLDALLIEVSRPDRRFDFVISTDVHRLSCDTA
                     TRTALLRALAVAGIEFLHAPEIRDGDRLPVMPWRLRSVDFIEVLTQLIRDGGHP"
     gene            4868..6850
                     /locus_tag="GA0070216_RS33200"
                     /old_locus_tag="GA0070216_1405"
     CDS             4868..6850
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012180850.1"
                     /locus_tag="GA0070216_RS33200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1405"
                     /product="recombinase family protein"
                     /protein_id="WP_245722896.1"
                     /transl_table=11
                     /translation="MTSTLPDWLRPPATTAPKRTIRVAFLGRTSTEEQQDPTLSIPRQL
                     TNSERALLPNMVIVAWFWDVESSRKELSQRGRGTAWQKFDVAVQRDGGLADMLEEATSP
                     DRRFDVVICESIDRIARWTHQGTKIEHDLELAGVPLLAADEPVMQSNSRKRAAQILLRR
                     TKQGVAEWYMIEMLEKSWDGFEEHTTQGWNVGKPPYGYLAEKHKHPVPAKRAEGKHKTK
                     LKIDPDRGPVVEQIYAWRIDEKLSYRAIAERLNTDLDRYPPPQPVDPARAVGRWTGSAV
                     REILVNPKYTGHMVWNRRSTKDKLHPGKVNPREQWVVSAQPTHPGIVPIETFLAAQNVS
                     RSRERSRADAHHGTPNRHRQTKRVYALRSYVWCTPCQRRMFGRTVTGYTYYSCQPRERA
                     IPEGHPSMISVTEDILLDFTDRFFNTYVLGPDRVRLAECSLDITAQQAADEQRRQIAVL
                     RRTLDDITTRRRRLLRVIEENDDPDGTVFAEISERRAQLDRDRETKTAELAHLEETMPS
                     DPGSADILAALPEMEVKLGLLPTDRLRRLLDAFAVQIYHDVRTNQVAFRATVSQHAAPH
                     LARLTRATADDPRTATHRHTSANDAAPADDDGGSDHLQFCDMPRRGHLEDQLMIPLACG
                     CARQAARRRCRHRRHGDHPSGLRTT"
     gene            complement(6918..7505)
                     /locus_tag="GA0070216_RS33205"
                     /old_locus_tag="GA0070216_1406"
     CDS             complement(6918..7505)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS33205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_1406"
                     /product="hypothetical protein"
                     /protein_id="WP_141723295.1"
                     /transl_table=11
                     /translation="MRLGIRQHVCGWLPRSPWWERSIAALGLMLLADSFLPWYRLSWTV
                     SRYGSGQQTRHVNTATAWHSSSGWSLAVLLGVIAAVGYVTCRAGTNRWPTLPARLRRLF
                     LLTATMSLLVATVSWLTIPSVDAPGGYGFVAADEIAGGVRFGDIVRDHLSARETNVTWG
                     FFIAVFITMALVLLMLLDIVRRTDRRAAAIAG"
     misc_feature    7494..7514
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.98"
                     /tool="antismash"
     gene            <7568..7687
                     /locus_tag="GA0070216_RS35980"
                     /old_locus_tag="GA0070216_1407"
                     /pseudo=""
     CDS             <7568..7687
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018790879.1"
                     /locus_tag="GA0070216_RS35980"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1407"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="VATRSSCSERTVKNVPHDITSRLQLRNRTHAVAYAVREG"
     gene            7712..8206
                     /locus_tag="GA0070216_RS33215"
                     /old_locus_tag="GA0070216_1408"
     CDS             7712..8206
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460923.1"
                     /locus_tag="GA0070216_RS33215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1408"
                     /product="EVE domain-containing protein"
                     /protein_id="WP_245722897.1"
                     /transl_table=11
                     /translation="MSHGRTDERQVTRDDLGAWLIKGNADLVDLAGRFARDPRVTSWCV
                     RPGYRARLMRAGQPVLFWASGSRGRLPYGVWGIGRLTGEPVPGGEARAPWTVPLDLTVL
                     PEPRRLHRDRLRADPRLAGLEVFRQPQAANPSYLTRAQFTALADHLPEAAPGHHRPPPR
                     S"
     gene            complement(8232..9422)
                     /locus_tag="GA0070216_RS33220"
                     /old_locus_tag="GA0070216_1409"
     CDS             complement(8232..9422)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="GA0070216_RS33220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_1409"
                     /product="cytochrome P450"
                     /protein_id="WP_091254790.1"
                     /sec_met_domain="p450 (E-value: 6.3e-13, bitscore: 38.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDDLPAFPLPPASGLAPAADFARRRAECPFGRVRLPSGDSAILL
                     VRHADVAAAVSSPALSRNHLLAQAPRRSGEPNFLYDPDLLINQSAQAHATVHRIATRAM
                     NHERVAAHRPVIHRIADALVDTMTDDGRPGGDLVAEYTDRLPLLTITRLLGIPAEDCDD
                     IRRWSGAYTHSHPGTPQERARLVADFGAYVRDVVTAAPRAALLADLVHPPDSGVRLSTD
                     ELVSLTRLMLSAGVEAPATVLGRAMLRLLADDAADWRTFVRRGTDPLAMADELLRLVYA
                     GNVAALRTATTDLVLPSGTVSRGGAVLLAWISALHDPAVYPRPEALLPGRRAPKFVGFG
                     GGRHYCPGRRLGRAILAVGLDRLRARLPGLRLATDGPIPIAEREVGAVVTTLPVRW"
     gene            complement(9543..10544)
                     /locus_tag="GA0070216_RS33225"
                     /old_locus_tag="GA0070216_14010"
     CDS             complement(9543..10544)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:TIGR04020.1"
                     /locus_tag="GA0070216_RS33225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14010"
                     /product="MupA/Atu3671 family FMN-dependent luciferase-like
                     monooxygenase"
                     /protein_id="WP_091254794.1"
                     /transl_table=11
                     /translation="MDLSLFFFSASADDAHDLLLDSARFADDHGFAAVWTPERHFHEFG
                     GPYPNPAVTGAAVAAVTRRVGVRAGSVVLPLHDPLRVAEEWAVVDRISHGRAGVAFASG
                     WHAVDFVLAPDRYPHRRSALPELIDEVRALWRGGTTPRPDGTGSHVDVEVFPKPVQADL
                     PVWITSAGDLATFELAGRLGVGVLTHLLTQSLDELRTKIERYRRLHPGQGRVTLMLHTL
                     VGTDDQGVSALAREPMTRYLRSSLDLVAGMLPDSPFHDPTITDDEADFLIGRVLDRFLA
                     ERGLFGSVPTCARTLRRLAEAGVDEVACLIDFGLPAAATRSGLTHLARLVGQ"
     gene            complement(10535..11770)
                     /locus_tag="GA0070216_RS33230"
                     /old_locus_tag="GA0070216_14011"
     CDS             complement(10535..11770)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (4-272). E-value:
                     5.6e-36. Score: 116.0. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33230_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="GA0070216_RS33230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14011"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_091254797.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-32, bitscore:
                     103.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQFVPTSPLQRGIWFNEQLAALGSAYTVAVTAHLRGPVDVGRLA
                     RACTALAARHPLLTAGCHNLDGLPWLAVGEHPLTLTVEPTADGTVRERVERAGRTRFDL
                     SAGPLARVWWFPLRNGGGVLVLAAHHLIVDGQSKDILLRDLADRYGPDAPPVVAAQPAG
                     PGYRTPPEHLVVAATEYWWRNPPRPVELPRDGGVRPGDTVVRALTPRTRTRLAEAAVAL
                     DATRFELLLTVLANCLTRDDGPVPIAIELSVRTPAEADRIGMYVNELPLTLPTPPTGSY
                     AAALTTVRAGLRELYAHRTVPLAMCRPGTRPFLATAAVSVSYRRIAPGPVFAGLATTVD
                     WSAFNGVARNALHVMIDDGEQTHVTFQFPASADVRGRADALIDRALAVLDRSLAAPHAT
                     LARSPEEPPPWT"
     aSDomain        complement(10955..11758)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33230_Condensation_L
                     CL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-36"
                     /label="GA0070216_RS33230_Condensation_LCL.1"
                     /locus_tag="GA0070216_RS33230"
                     /protein_end="272"
                     /protein_start="4"
                     /score="116.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLIVDG"
                     /tool="antismash"
                     /translation="VPTSPLQRGIWFNEQLAALGSAYTVAVTAHLRGPVDVGRLARACT
                     ALAARHPLLTAGCHNLDGLPWLAVGEHPLTLTVEPTADGTVRERVERAGRTRFDLSAGP
                     LARVWWFPLRNGGGVLVLAAHHLIVDGQSKDILLRDLADRYGPDAPPVVAAQPAGPGYR
                     TPPEHLVVAATEYWWRNPPRPVELPRDGGVRPGDTVVRALTPRTRTRLAEAAVALDATR
                     FELLLTVLANCLTRDDGPVPIAIELSVRTPAEADRIGMYVNELPLT"
     CDS_motif       complement(11336..11401)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33230_0002"
                     /evalue="1.40E-07"
                     /label="NRPS-E2"
                     /locus_tag="GA0070216_RS33230"
                     /protein_end="145"
                     /protein_start="123"
                     /score="24.0"
                     /tool="antismash"
                     /translation="LVLAAHHLIVDGQSKDILLRDL"
     CDS_motif       complement(11597..11698)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33230_0001"
                     /evalue="2.60E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="GA0070216_RS33230"
                     /protein_end="58"
                     /protein_start="24"
                     /score="32.7"
                     /tool="antismash"
                     /translation="SAYTVAVTAHLRGPVDVGRLARACTALAARHPLL"
     gene            complement(11767..13467)
                     /locus_tag="GA0070216_RS33235"
                     /old_locus_tag="GA0070216_14012"
     CDS             complement(11767..13467)
                     /NRPS_PKS="Domain: AMP-binding (11-383). E-value: 1.5e-60.
                     Score: 196.9. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33235_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (492-560). E-value: 3.2e-21. Score:
                     67.3. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33235_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="GA0070216_RS33235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14012"
                     /product="AMP-binding protein"
                     /protein_id="WP_091254799.1"
                     /sec_met_domain="AMP-binding (E-value: 5.4e-60, bitscore:
                     193.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.9e-13, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGPTVPGLLRQRAADTPDAVALCHLDGATLTFAQWDRSADALA
                     AALADDGLRVGQRVALLFDEREWFGYATAFCGVLRAGGVAVPLSARLPPGQLVARVTVA
                     GAVGIIREGCAVPAELGGWQRGPAGAATDAVPDRATPDGAAQIIFTSGTEGSARAVVAT
                     HGNLTHGHDTTPGRRQLAHSRYFLHAFPIGTNAAQTMLLTGLAAEPAALVVPRFDAAEV
                     CAAVEEFRVGTLFLVPSMARELLASGEPDRRDLSSLVLVGTTGDVLPAAVARALGDVLP
                     YATIVNTYSSTEAAPARTTMVFDSRRPDAVGRGAVRITDDAGREVAAREVGQVWIGSDA
                     PPRRYLDGGDAATFRDGWTRTGDRGRLDDEGYLHLTGRDASTIHSGGTKVSSFAVEQAL
                     HGHPDVRDCAVVAVADPVWGERPAAVLVTRTGAVPADLRAFLAGRLSGPEIPQRVVCVD
                     ALPRNDGGKVVARSLRGLFPPAGSTPAAAPVTVVERRLADIWASVLGVAAVGRDDDFLA
                     LGGNSMSALRLARLVSDQFAVATPVSALYARPGLAAQAAWIADRMSGSP"
     aSDomain        complement(11788..11991)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33235_PCP.1"
                     /evalue="3.20E-21"
                     /label="GA0070216_RS33235_PCP.1"
                     /locus_tag="GA0070216_RS33235"
                     /protein_end="560"
                     /protein_start="492"
                     /score="67.3"
                     /tool="antismash"
                     /translation="ERRLADIWASVLGVAAVGRDDDFLALGGNSMSALRLARLVSDQFA
                     VATPVSALYARPGLAAQAAWIAD"
     aSModule        complement(11788..13434)
                     /complete
                     /domains="nrpspksdomains_GA0070216_RS33235_AMP-binding.1"
                     /domains="nrpspksdomains_GA0070216_RS33235_PCP.1"
                     /locus_tags="GA0070216_RS33235"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(12319..13434)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33235_AMP-binding.1"
                     /evalue="1.50E-60"
                     /label="GA0070216_RS33235_AMP-binding.1"
                     /locus_tag="GA0070216_RS33235"
                     /protein_end="383"
                     /protein_start="11"
                     /score="196.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RQRAADTPDAVALCHLDGATLTFAQWDRSADALAAALADDGLRVG
                     QRVALLFDEREWFGYATAFCGVLRAGGVAVPLSARLPPGQLVARVTVAGAVGIIREGCA
                     VPAELGGWQRGPAGAATDAVPDRATPDGAAQIIFTSGTEGSARAVVATHGNLTHGHDTT
                     PGRRQLAHSRYFLHAFPIGTNAAQTMLLTGLAAEPAALVVPRFDAAEVCAAVEEFRVGT
                     LFLVPSMARELLASGEPDRRDLSSLVLVGTTGDVLPAAVARALGDVLPYATIVNTYSST
                     EAAPARTTMVFDSRRPDAVGRGAVRITDDAGREVAAREVGQVWIGSDAPPRRYLDGGDA
                     ATFRDGWTRTGDRGRLDDEGYLHLTGRDASTI"
     CDS_motif       complement(12976..13032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33235_0002"
                     /evalue="6.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070216_RS33235"
                     /protein_end="164"
                     /protein_start="145"
                     /score="12.7"
                     /tool="antismash"
                     /translation="QIIFTSGTEGSARAVVATH"
     CDS_motif       complement(13204..13239)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33235_0001"
                     /evalue="9.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="GA0070216_RS33235"
                     /protein_end="88"
                     /protein_start="76"
                     /score="9.8"
                     /tool="antismash"
                     /translation="GVLRAGGVAVPL"
     gene            complement(13464..15161)
                     /locus_tag="GA0070216_RS33240"
                     /old_locus_tag="GA0070216_14013"
     CDS             complement(13464..15161)
                     /NRPS_PKS="Domain: AMP-binding (8-389). E-value: 2.2e-82.
                     Score: 268.7. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33240_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (491-558). E-value: 1.2e-12. Score:
                     39.9. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33240_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="GA0070216_RS33240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14013"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_176739271.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-92, bitscore:
                     300.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-12, bitscore:
                     37.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRVSTLARRFPHRVALADRTGAVTYADLDQRADVLADTLSGAG
                     VGPATVVAVALERGVPLVTAALAIWRSGGVLLPLDPASPPAWNQSVATAADATVLVSTS
                     VLHRAPGMRQVDPTRPAAGSPRPGGRPAAGDPTGLAYVIPTAGTTGTPKLVMIGHDAVV
                     NLMVAQRRWFGDLGDDARVLLYAGPVADGWIFELLLGLGAACRLEVVDRESLVGAPLAR
                     LLAERAVTHAALPAAVLDSLPEDDLPRLRTMLSVGSPLAPATARRWIDRCELVNGYGPT
                     EATVASTLHRVSRADTDGERIPVGRPIAGYDIFVVDPDGQVVADGQPGEIVIVGRGVAR
                     GYLNAPELTAARFGQVDGSRSYRTGDRGRRDADGLVHLLGRMDAQVKVRGFRVEPAGVE
                     AALLRLPGVRSAAVSAVAADAGPVSLVAHVVSTPGYQPSGTALRAALARAVPAHLVPDL
                     VVVVDALPLTAAGKVDRRRLAVPAGSRPPHTPTEHAIAAIVEELVGVDGVGLDDDLTDV
                     GWHSLLTTQVAFRIERRLGIRLALEEIVRAGTIGRIAAVAAGRAPDPR"
     aSDomain        complement(13488..13688)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33240_PCP.1"
                     /evalue="1.20E-12"
                     /label="GA0070216_RS33240_PCP.1"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="558"
                     /protein_start="491"
                     /score="39.9"
                     /tool="antismash"
                     /translation="EHAIAAIVEELVGVDGVGLDDDLTDVGWHSLLTTQVAFRIERRLG
                     IRLALEEIVRAGTIGRIAAVAA"
     aSModule        complement(13488..15137)
                     /complete
                     /domains="nrpspksdomains_GA0070216_RS33240_AMP-binding.1"
                     /domains="nrpspksdomains_GA0070216_RS33240_PCP.1"
                     /locus_tags="GA0070216_RS33240"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(13674..13697)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0006"
                     /evalue="3.30E+01"
                     /label="NRPS-A_a5"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="496"
                     /protein_start="488"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="TPTEHAIA"
     CDS_motif       complement(13965..14027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0005"
                     /evalue="3.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="399"
                     /protein_start="378"
                     /score="29.0"
                     /tool="antismash"
                     /translation="LGRMDAQVKVRGFRVEPAGVE"
     aSDomain        complement(13995..15137)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33240_AMP-binding.1"
                     /evalue="2.20E-82"
                     /label="GA0070216_RS33240_AMP-binding.1"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="389"
                     /protein_start="8"
                     /score="268.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARRFPHRVALADRTGAVTYADLDQRADVLADTLSGAGVGPATVVA
                     VALERGVPLVTAALAIWRSGGVLLPLDPASPPAWNQSVATAADATVLVSTSVLHRAPGM
                     RQVDPTRPAAGSPRPGGRPAAGDPTGLAYVIPTAGTTGTPKLVMIGHDAVVNLMVAQRR
                     WFGDLGDDARVLLYAGPVADGWIFELLLGLGAACRLEVVDRESLVGAPLARLLAERAVT
                     HAALPAAVLDSLPEDDLPRLRTMLSVGSPLAPATARRWIDRCELVNGYGPTEATVASTL
                     HRVSRADTDGERIPVGRPIAGYDIFVVDPDGQVVADGQPGEIVIVGRGVARGYLNAPEL
                     TAARFGQVDGSRSYRTGDRGRRDADGLVHLLGRMDAQVKVR"
     CDS_motif       complement(14103..14189)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0004"
                     /evalue="2.50E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="353"
                     /protein_start="324"
                     /score="45.4"
                     /tool="antismash"
                     /translation="DGQPGEIVIVGRGVARGYLNAPELTAARF"
     CDS_motif       complement(14304..14330)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0003"
                     /evalue="6.10E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="286"
                     /protein_start="277"
                     /score="9.3"
                     /tool="antismash"
                     /translation="YGPTEATVA"
     CDS_motif       complement(14685..14744)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0002"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="159"
                     /protein_start="139"
                     /score="23.2"
                     /tool="antismash"
                     /translation="AYVIPTAGTTGTPKLVMIGH"
     CDS_motif       complement(14922..14963)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33240_0001"
                     /evalue="5.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="GA0070216_RS33240"
                     /protein_end="80"
                     /protein_start="66"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LAIWRSGGVLLPLD"
     misc_feature    15233..15245
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            15390..16370
                     /locus_tag="GA0070216_RS33245"
                     /old_locus_tag="GA0070216_14014"
     CDS             15390..16370
                     /NRPS_PKS="Domain: PKS_ER (13-322). E-value: 9.8e-26.
                     Score: 82.5. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS33245_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020524338.1"
                     /locus_tag="GA0070216_RS33245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14014"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_091254803.1"
                     /sec_met_domain="ADH_N (E-value: 2.9e-09, bitscore: 27.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-18, bitscore:
                     57.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIRLHRFGPATNLVLDDLPDLAPAPGQVRIAVAASGVHLLDTA
                     LRRGEAGGPLPLPALPTVPGREVAGTVDLVGAGVDEAWRGRRVVAHLGMVPGGYAEQAV
                     TAVESLHVVPEGTGFADAVALVGTGRTALGVFELAPPTADDVVLVLSAAGGMGWLLVQA
                     ARTVGATVVAAARGARRTARVGELGADVVVVDYDRPDWTDLVRARVGGPTLVYDGVGGT
                     LGRAALESTASGGRFVMFGWSAGEPTRVGTADLVERSLTAGWLGQRLRNRPGGIAGLAA
                     RSVELGGRGWWQPLVSTYPLAEAAAAHADLEGRRALGKVVLTVGG"
     aSDomain        15429..16355
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS33245_PKS_ER.1"
                     /evalue="9.80E-26"
                     /label="GA0070216_RS33245_PKS_ER.1"
                     /locus_tag="GA0070216_RS33245"
                     /protein_end="322"
                     /protein_start="13"
                     /score="82.5"
                     /tool="antismash"
                     /translation="NLVLDDLPDLAPAPGQVRIAVAASGVHLLDTALRRGEAGGPLPLP
                     ALPTVPGREVAGTVDLVGAGVDEAWRGRRVVAHLGMVPGGYAEQAVTAVESLHVVPEGT
                     GFADAVALVGTGRTALGVFELAPPTADDVVLVLSAAGGMGWLLVQAARTVGATVVAAAR
                     GARRTARVGELGADVVVVDYDRPDWTDLVRARVGGPTLVYDGVGGTLGRAALESTASGG
                     RFVMFGWSAGEPTRVGTADLVERSLTAGWLGQRLRNRPGGIAGLAARSVELGGRGWWQP
                     LVSTYPLAEAAAAHADLEGRRALGKVVL"
     CDS_motif       15822..15878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS33245_0001"
                     /evalue="1.10E-02"
                     /label="PKSI-ER_m5"
                     /locus_tag="GA0070216_RS33245"
                     /protein_end="163"
                     /protein_start="144"
                     /score="8.6"
                     /tool="antismash"
                     /translation="DVVLVLSAAGGMGWLLVQA"
     gene            complement(16619..17215)
                     /locus_tag="GA0070216_RS33250"
                     /old_locus_tag="GA0070216_14015"
     CDS             complement(16619..17215)
                     /GO_function="GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455216.1"
                     /locus_tag="GA0070216_RS33250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14015"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_091254805.1"
                     /transl_table=11
                     /translation="MIGYDVRMLDGGQPAFGDQVFERLLRERIIFLGTEVTDASANQIC
                     AQILLLAAEDSKRDIYLYINSPGGSVSAGMAVYDTMRYVRNDVATLALGMAGSMGQFLL
                     CAGAAGKRFALPHARVMMHQPSGGIGGTAADITIQAENMLHVKRTMQELIAEHSGRTLD
                     EIQADWDRDRWFTAEQAREYGLIDQVLTRVDQLPG"
     gene            complement(17351..17992)
                     /locus_tag="GA0070216_RS33255"
                     /old_locus_tag="GA0070216_14016"
     CDS             complement(17351..17992)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455217.1"
                     /locus_tag="GA0070216_RS33255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14016"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_091254818.1"
                     /transl_table=11
                     /translation="MSLLRRVIGGVLRRVRLRQGRTLREVAAAAGVSLPYLSEVERGRK
                     EASSEVLAAICRALGIHLSDLLEEARDELRRVERGVPVPPGGSLARLDRVPTARRAGSG
                     PHLQIGPPTAGFARPTAAVGPSTARCGPPRAVVGRPTGSGPMLRLGDGVVLAGGALSPV
                     GAGASGFAAVTVAVPVRVIAVVSTARPAARTPRVPARRRARAGRRRLLVG"
     gene            18265..19281
                     /locus_tag="GA0070216_RS33260"
                     /old_locus_tag="GA0070216_14017"
     CDS             18265..19281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018741731.1"
                     /locus_tag="GA0070216_RS33260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14017"
                     /product="potassium channel family protein"
                     /protein_id="WP_091254807.1"
                     /transl_table=11
                     /translation="MIHFPAQRRGPLSALSLRLAAALGLVLLTVAVVYLDRSGYRDVDE
                     NGLTLLDCFYYAVVTLSTTGYGDITPFAQSARLVNVLFITPARVIFLIILVGTTLEVLT
                     EQYRTGRRLGRWRRTVKDHVIICGYGTKGRSAVSALLENGLDKSRIVVVERNGTALRQA
                     TSAGLVAIEGSATRSSVLEEAHVRNAKAVIIATDSDDASVLVALTTRQLTAGQVRIIAA
                     VREAENAPLLRQSGAHHVIVSSATAGRLLGLSTSAPPLIDVVEDLLTPGQGMALAMRSA
                     ERHEVGKSPRELESLVIALVRRGKVVTLADRAGAVIETGDMLVHVRDDRPTANTTAS"
     gene            complement(19359..>20183)
                     /locus_tag="GA0070216_RS33265"
                     /old_locus_tag="GA0070216_14018"
     CDS             complement(19359..>20183)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018218416.1"
                     /locus_tag="GA0070216_RS33265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_14018"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_091254809.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.8e-31, bitscore:
                     99.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HSIHGRAPAIATGLSVTRPDLSVWVVTGDGDALSIGGNHLIHALR
                     RNVNLKILLFNNRIYGLTKGQYSPTSETGKITKSTPAGSADAPFNPLSLALGAEATFVA
                     RTIDSDRKHLQSVLRAAAQHQGSAFVEIYQNCNIFNDGAFEQLKQPDTRDDYLIPLEHG
                     QPITFGHNGQHCIVHPPRGFGLEVRDTATTPADDIVIHDTTITDPAYAFALSRLPGPDL
                     RNTPIGVFRQTHRPSYDNLVQQQLTTAKATTTHTPEQQLTALLATGDTWTIS"
ORIGIN
        1 ctgggcctga cccgttttga cggacatccg agatcaggag cccggtgggc tccgggagga
       61 tgtccagcat catggagagc atgggtaaga agcggccccg gcctcgccgg tcgttcacgg
      121 cgcagttcaa ggccgagatc gttgagctgt gtcagcgtgg ggaccgcacg atcaggcagg
      181 tcagcgacga tttcgacttg accgagaccg cggtgcgtga ctgggtcaag caagccgaac
      241 tcgacaccgg tacccgctcc gacgggctga gcagcgacga gaaggccgaa ctcgcccaac
      301 tgcggcggga aaaccgccgg ttgcgcgagg acgtcgatat cttgaagcgg gcgacggctt
      361 tcttcgcgaa ggagacccgg tgaacgtgta cccgttcatc gaggcggaga aggccggcaa
      421 gcacaacgtc acacgcgcgt gcgagctgat gaaggtctcc cgatccgcct actaccagca
      481 cgccaccggt cagcagtcgc agcgagacct gaccgaccag gcgctgaccg cgaagatcat
      541 cgaggtgcac gcgatgtcga agggcaccta cggagccccc cgggtgcacg ccgaactgac
      601 cgacgccggg ctgcggcacg gacgtaaacg catcgcccgg ctgatgcgcg acgtcggcgt
      661 gcgcggcaag agcccgcgcc ggtggcagac gaccaccatc accgaccccg cggcagccga
      721 tcgtgcggac ctgatcggtc gggacttcac caccgacccc gcccgcatcg acacccgctg
      781 gtgcggagac atcacctaca tcaacacgtg gcagggctgg ctgtatctgg ccactgtcat
      841 cgacctggca tcccgtcgcg tcgtgggctg ggccgtcgcc gatcacctca aaaccgacct
      901 gatcgatgcc gccctgaacg acgcgatcgt gcggcgccgc ccaccgtctg ggctgatctt
      961 ccactccgac cgcggctgcc agtacaccag cgcccaacac gcccgcctcg ccgccaccca
     1021 cagcatccgc ctgtccaaca gccgtcgcgg gcaatgctgg gacaacgcgg tagccgagtc
     1081 cttcttcgct acggtcaaga ccgaactgct gcaccggcag ccgtggccca cacacaccgc
     1141 cgcccgccag gccacattcg agtacatcga aggctggtac aacacccgtc gccggcactc
     1201 ctcgctgggc tacctcagcc cagccgccta cgaagccacc cgccacacca ttcaaccggt
     1261 acaccaggcc gcctagataa gatcaccaca tcgaccccgt ccgtcgaaac gggtcaagcc
     1321 cagccctcgt cgcctccgac tgtggagacc cccaccttgc ccgcgcctgg tgccgtcgcc
     1381 acgccagcct ctacctcagc caagccccgc tgaacggcta cacggcccgc ttcgctctcg
     1441 aaccagtcgt caacctcgct cgcctgcgca ttcgtggagg cgacggcgac ggcgcgtacc
     1501 gcctactcac gcacctatac gcggccatcg tcggcggcac tcccgctctt ctggacgacc
     1561 tggaaataca tcctcgacaa cttcccgccg atcccgaaga actcaatcag atcatcagtt
     1621 ggctgcgcgg caccctgctc tccgacggaa cccgtgccct caccctcgcc ggacggtggg
     1681 acgacgccgt gaaccatgta cgccgatacg acggaatcgg accgaccctt cttgatggac
     1741 gacaggtcgc aatcgtcgct catctgctgc gggccgaagg gccgtcagca gcggctctcc
     1801 tcgcggccac caaaatcgag gcgccgtggg agcaagcggt gcatgggctc ctcaagacct
     1861 ggcaggagct ggccgtgggg acggtcgccg tcgaccacgc tgaactcatc gatcgagtgt
     1921 ccgccgtacc gcgaactccc gggctcgcag tgttccgcgt tcgcctcgga ctgacggccc
     1981 tggacctctc gacgggcttg ccaaccgatg tcgtagacaa cctgaccaaa cagctggtgg
     2041 cagatgcgac ccacgacgag gacgccaacg cggcacgcga ccttatcaac cacccggctg
     2101 tcacggccga acaccaaggg acgctacgcc cgttgatgaa ggcgagcggg ttagaccagg
     2161 gctacctgcc agctacggcg aatgatccgc tttccgtggc gctcgatctg gccggggccg
     2221 taatcgctat gcgacgtgat cgagggcggg gagcgggact acatgcacgg acgcagtgat
     2281 ctgactccac gagtcacccg tgtcgatgac cagctccgga tgcacggcca cggttcattg
     2341 aacggggaag gtccggcgtt gcgggtatac ggcacgccgc tcggcccaag ccctcgaccg
     2401 gcactcgttc ggatatgcgc cttgcgccta acgccatcgt cgaggccgtg gtgagcacga
     2461 cctatctggc cagcgtggca ctggaagaga tcgaacgagc ccaggcagaa ctcgaacgcc
     2521 acctgacggt ccgaccatcc ggagagtgtg tgacgtgcgg tgagatcgag ccgtgctctg
     2581 gacgccaaga cgccggcacc atgatcatca aatatgggcg tctgccacgc cgtcgaccag
     2641 gagcttcggg ggtgcgccgc gccgcgccga ccacggcggg tgctgccccg acttcgtggt
     2701 tcgcgtcggc gaccgacggc gacggtcacg agctgaccgg gacgggatcc gaggcatagg
     2761 cgcgcacggg gatgccgcag ttcggtcgct ggaagtgcgc cgagcagggg gcgttctcgg
     2821 ggggtgagtc ggccgagttc ggcggccacg acggacgccg ccaggcgggg gactgccggt
     2881 ggcagatgtg cgggtaggag ggattctctt atcagtcggt tccggtccac cggccctcct
     2941 cacccccgtt gacgtgcttg tacgacgtac tgaagggggc gttctcaccc ggctgttcgt
     3001 ggtcgttgcg ttcctcgttg gatcactcgt tagacatctc gttagaaccc tcacccctga
     3061 acagcacgtg tttcgcggcc aatcagctcg accgatgcaa gctcagcggg cgccgaggat
     3121 tcgggcttgg gcttaccgcg gtcacccctc catgggacga gcgccgctgc gagggggacg
     3181 gtcggacagg gcgagtaggc ggcggggacg gaggccatcc ggcgcggacg gcggacgggg
     3241 acggggacgg cggggtcgca ctggttggtg cggacggcct cgcaggacga ggcgcggaga
     3301 cggggtcgcc gaccgcccgg gacggcggac ggggttggcg gacgggtcgt gccgacgcac
     3361 cgcaccacat ggcgatctcg tccacggccc gaggcggtca gccaggtcgc gcgttcaagc
     3421 aaaaggtgat cttgttcaag tgggtgaaga ttctgtgcaa tctgtcgctg atcacatcgg
     3481 cgttccacgc cgctcccgtg ccgcctgaag ccggcacctc acgagcctga cctgtgtatt
     3541 caacccgttg aggatcttgt tcaaccgggc gtcggcgggc gatgcgagtt gttcggcgcg
     3601 gagcgcggtt tccaatccga ggcccgaatt tgtaatccct tagtgtcagc gcttgtcggc
     3661 ggacgtggcc cacacgccca tgccgaagcc cagcttcacc acccccggcg accggcccca
     3721 gccggcaact gccggtttgc tccttccccc tatccatgtc ccccgcaccc ccgatccgga
     3781 agtaccggac gggcacggac cgtccgcccc ggaggcggac gacggcagac atcgcggggt
     3841 gtcgaccccg cccgatcgcg agtctccggc ttgcggtgac gggcagtcgg cagagggcac
     3901 ggttgcccgc ggtgatgtgc cggaggtgcg gttcgacgtc accgtgctcg atggtgaggc
     3961 cggtcggcgg ccggccgtac tgcaagccga ggcgatcctc gacgtgctga cctggcttca
     4021 cgaccagcag caccacgccg agcccgtctg accggtcgcc ctccgggcca ctcggtgtgc
     4081 cgtggccggt gttgccctcg gggcggtctt gatccctttc cggagttgag cggtgatcga
     4141 cgtccacggg tcgaccggca gcaccagcgg tcggcccgtg gcccgacccg acgccaacca
     4201 accgcaggag gtacgcacgt catgtacgcc accgtcggcc acgacgacac cggcagcatc
     4261 gtcgtctacg gcccccacga cacaccggcc atcgcaccga acgatggggc agtcaccgtc
     4321 gccatctgcc cagcgggggc cgctgacggc acgaccggca ccctggccga ggtatgaaca
     4381 tccaccgcac gaccgtgctc ccgcgtgtgg cgttctacgg ccggaccgcc gaggccaggg
     4441 acctcgccac ggcggcccgc gtggtcggcg gtcagtacca gcagtgcgtc tcggtgctgc
     4501 ctgacggcgc gatcacggcg gtgttctccg acctcggcac tcggcccgac tatcggcggg
     4561 cacccgccaa cctcttcctc gaccacgagc gggagatcag ccgtgacggt ggtctggatg
     4621 ccctgctcat cgaggtgagc cggccagatc gccggttcga cttcgtgatc agcaccgacg
     4681 tccaccgcct gtcctgcgac acggcgacga ggaccgcgct gctgcgtgcg ctcgcggtcg
     4741 ccggcatcga gttcctccac gcccccgaga tccgcgacgg tgaccgacta ccggtcatgc
     4801 cctggcgact gcgcagcgtc gacttcatcg aggtgctgac tcaactcatc cgcgacggag
     4861 gccacccgtg acgagcaccc tgcccgactg gctacgccca cccgccacca cagccccgaa
     4921 gcggacgata cgggtcgcgt tcctcgggcg tacctcgacc gaggagcagc aggaccccac
     4981 gctgtcgatc ccccggcagt tgaccaactc cgaacgggcg ctgctgccca acatggtcat
     5041 cgtggcgtgg ttctgggacg tggaatcctc ccgcaaggaa ctcagccagc gcggccgggg
     5101 caccgcgtgg cagaagttcg acgtcgccgt gcaacgagac ggcggcctcg ccgacatgct
     5161 ggaagaggcc acctcgccgg atcgccgctt cgatgtggtc atctgcgagt cgatcgaccg
     5221 catcgcccgc tggacccacc agggcaccaa gatcgagcac gaccttgaac tcgccggggt
     5281 gcctctgctg gccgccgacg agccggtcat gcaatcgaac agccgcaaac gggccgccca
     5341 gatcctcctg cgccggacga agcagggcgt cgccgagtgg tacatgatcg agatgctgga
     5401 gaagtcgtgg gacggcttcg aggaacacac cacccagggc tggaacgtcg gcaagcctcc
     5461 atacggctac ctcgccgaga agcacaaaca cccggttccc gccaagcggg cggaaggcaa
     5521 gcacaagacc aagctgaaga tcgaccccga ccgggggccg gtggtcgagc agatctacgc
     5581 ctggcgcatc gacgagaagc tgtcctaccg ggccatcgcc gaacggctca acaccgacct
     5641 cgaccgctac ccgcccccac aacctgtcga tcccgcccgc gcggtcggac gatggaccgg
     5701 ctcagcggtc cgcgagatcc tcgtcaaccc caagtacacc ggccacatgg tgtggaaccg
     5761 gcgttcgacc aaagacaaac tgcaccccgg caaggtcaac ccccgtgagc agtgggtcgt
     5821 ctccgcacag cccacccacc cgggcatcgt gccgatcgag acgttcctcg ccgcacagaa
     5881 cgtgagccga tcccgagaac gctcccgcgc agacgcccac cacgggaccc ccaaccggca
     5941 ccgacagacc aaacgggtct acgcgctgcg ctcctacgtc tggtgcaccc cgtgccaacg
     6001 acgcatgttc ggccggaccg tcaccggata cacctactac tcctgccaac cccgagagag
     6061 ggccatcccc gaaggacatc cgagcatgat ctcggtgacc gaagacatcc tgctcgactt
     6121 caccgaccgg ttcttcaaca cctacgtcct cggccccgac cgggtacgcc tcgccgaatg
     6181 cagcctcgac atcaccgccc aacaggcagc tgacgagcaa cggcgacaga tcgccgtcct
     6241 gcggaggacc ttggacgaca tcaccacccg ccgccgacgc ctcctacgcg tcatcgagga
     6301 gaacgacgac cccgacggca ccgtgttcgc cgaaatctcc gaacgccgag cccaactcga
     6361 ccgcgaccgc gagaccaaga ccgccgaact cgcccacctc gaagaaacca tgccctccga
     6421 ccccggcagt gccgacatcc tcgccgccct acccgagatg gaagtcaaac ttggcctact
     6481 accgaccgac cgcctccgtc gcctcctgga cgccttcgcc gtgcagatct accacgatgt
     6541 ccgaaccaac caggtcgcgt tccgagccac cgtcagccaa cacgccgccc cacacctggc
     6601 ccggctaacc cgcgccacgg cagacgaccc ccgcaccgcc acccatcgcc acaccagcgc
     6661 aaacgacgct gcccccgccg acgacgacgg gggcagcgac catttgcagt tctgtgacat
     6721 gccccgccgg gggcacctcg aagatcagct aatgatccct ctggcctgtg gatgtgctcg
     6781 gcaagccgcg cgcaggaggt gccggcaccg acggcacggc gaccatccct cgggcctccg
     6841 caccacctaa ccggcgtagg gctgcaggct gatgcccttc ggccaccctg tggcccggcc
     6901 gtgcggcagt ccctgcccta tccggcgatg gcggcagcac ggcggtcggt gcgccgaaca
     6961 atatccagga gcatgagcag caccagcgcc atcgtgatga acactgcgat gaagaagccc
     7021 caggtcacat tcgtctccct ggcggagaga tggtcacgca caatgtcgcc gaacctgacc
     7081 ccacccgcga tctcgtccgc agcgacgaag ccgtagccgc ctggcgcgtc cactgagggg
     7141 atcgtcaacc aggagacggt tgccacgagc agactcatcg tcgcggtgag cagaaacagc
     7201 cggcgcagcc gtgccggcag cgtcggccac ctgttggtac cggcgcggca ggtcacataa
     7261 ccgactgccg cgatgacgcc gaggagcacg gccagcgacc agccggatga gctgtgccat
     7321 gccgtagccg tgttgacgtg gcgggtttgc tgtccgctgc cgtaccggct gaccgtccag
     7381 ctcagccggt accaggggag gaagctgtcg gcgagcagca tcaagccgag cgccgcgatg
     7441 gatcgctccc accacggtga gcgtgggagc catccgcaga cgtgttgccg gataccgagt
     7501 cgcatagacg aatgttggcc tattgccacg ttccccgttt cccggggtga acgcgcaggt
     7561 gcgggaggtg gcgacccggt cgagctgctc ggagcggacc gtcaagaacg tgccgcacga
     7621 catcaccagc cggctccagc tgcgcaaccg cacccacgcg gtagcctacg cggtccgtga
     7681 gggctgatct gaccgccgag gaggacccga cgtgtcgcac ggacgcaccg acgaacgtca
     7741 ggtgacccgg gacgacctgg gcgcctggct gatcaagggc aatgcggacc tggtcgacct
     7801 cgccggccgg ttcgcccggg acccccgggt gacgagctgg tgcgtacgcc ccggctaccg
     7861 ggcccggctg atgcgggccg gtcagcccgt gctcttctgg gccagcggca gccgggggcg
     7921 gttgccgtac ggcgtctggg ggatcggccg gctcaccggc gagccggtgc ccggcgggga
     7981 ggcccgcgcg ccctggacgg tgccgctgga cctgaccgtc ctgcccgagc cacgacggct
     8041 gcaccgggac cggttgcgcg ccgatccccg gctggccggg ctggaggtgt tccgccagcc
     8101 acaggccgcc aacccgtcgt acctgacccg ggcgcagttc accgccctcg ccgaccacct
     8161 gcccgaggcg gcaccgggac accaccggcc gccaccgcgg agctgagccc gctccccccg
     8221 gggaaccggc tctaccagcg caccggcaac gtggtgacga cggcgccgac ctcccgttcc
     8281 gcgatgggga tcggcccgtc ggtggcgagc cggagcccgg gcagcctggc gcgcagccgg
     8341 tccagcccca ccgccaggat cgcccggccg agccgccgcc ccgggcagta gtggcggcca
     8401 ccgccgaacc ccacgaactt cggtgcccgg cgaccgggca gcagcgcctc cgggcgggga
     8461 tagacggccg ggtcgtgcag cgccgagatc cacgcgagga gcacggcccc gccccgcgag
     8521 acggtccccg acggcagcac gaggtcggtg gtcgcggtcc gcagggcggc cacgttgccg
     8581 gcgtagacga ggcggagcag ctcgtcggcc atggcgaggg gatcggtgcc gcgccggacg
     8641 aacgtccgcc agtcggccgc gtcgtcggcc aggagccgca acatcgcccg gccgagcacg
     8701 gtcgccgggg cctccacccc cgccgacagc atcagtctgg tcaggctgac cagctcgtcc
     8761 gtcgagagcc tgaccccgct gtcgggcggg tgcacgagat cggccagcag cgcggcgcgc
     8821 ggcgcggcgg tgacgacgtc gcggacgtac gcgccgaagt cggcgacgag ccgcgcccgt
     8881 tcctgcggcg tgccgggatg ggagtgggtg tacgcccccg accagcggcg gatgtcgtcg
     8941 cagtcctcgg ccggtatccc gagcagtcgg gtgatcgtca gcagggggag ccggtcggtg
     9001 tactcggcga cgaggtcgcc accggggcgg ccgtcgtcgg tcatggtgtc gacgagcgcg
     9061 tcggcgatgc ggtggatcac cggtcggtgg gccgcgaccc gttcgtggtt catcgcccgg
     9121 gtggcgatcc ggtggaccgt cgcgtgcgcc tgcgcggact ggttgatcag caggtccggg
     9181 tcgtagagga agttgggttc gccgctgcgc cggggggcct gcgcgagcag gtggttgcgg
     9241 gacagtgccg ggctgctgac ggcggcggcg acgtcggcgt gccggacgag caggatcgcg
     9301 ctgtcgccgc tgggcagccg gacgcggccg aacgggcatt ccgcgcgccg tcgggcgaag
     9361 tcggcggcgg gagcgagccc cgacgcgggc ggcagcggga atgcgggaag gtcgtcgtcc
     9421 atcagcgctc cttcgctcgg cagacgtggg tgtgggcacc gcccgacgcg ggcgccggca
     9481 ccgcagggcg gccggtggcg cgggcgctgc cggtacgccc gggccggggc ccgccgccgg
     9541 ggtcactgcc cgaccagccg ggccaggtgg gtgagaccgg acctggtcgc cgccgccggc
     9601 aggccgaagt cgatcaggca ggcgacctcg tccacgcccg cctcggcgag ccggcgcagg
     9661 gtacgggcgc aggtcggcac cgagccgaag agcccccgtt cggccaggaa ccggtcgagc
     9721 acccggccga tgaggaagtc cgcttcgtcg tcggtgatcg tggggtcgtg aaaaggggag
     9781 tccggcagca tccccgccac gaggtcgagc gaggaccgca ggtaccgggt catcggctcc
     9841 cgggccaggg cggacacacc ttggtcgtcc gttccgacca gggtgtgcag catgagggtg
     9901 acccggccct gtccggggtg cagccgtcgg taccgctcga tcttggtgcg cagctcgtcg
     9961 aggctctggg tgagcaggtg ggtgaggacg ccgacgccga gccgcccggc gagttcgaag
    10021 gtggccaggt caccggcgct ggtgatccag accggcaggt cggcctgcac cggcttgggg
    10081 aagacctcga cgtcgacgtg actgccggtg ccgtcgggac gtggcgtcgt gccgccccgc
    10141 cacagggcac gcacctcgtc gatcagctcc ggcaacgccg acctgcggtg cgggtaccgg
    10201 tcgggggcga ggacgaagtc gacggcgtgc caaccggagg cgaacgcgac cccggccctg
    10261 ccgtgggaga tccggtccac gaccgcccac tcctcggcca cccgcaacgg gtcgtgcagg
    10321 gggagcacga cgctgccggc gcggacaccg acccgccggg tgaccgccgc gacggcggca
    10381 ccggtcaccg ccgggttcgg gtaggggccg ccgaattcgt ggaagtgccg ctccggcgtc
    10441 cagaccgccg cgaagccgtg gtcgtcggcg aaccgtgcgc tgtcgagcag caggtcgtgg
    10501 gcgtcgtcgg cgctggcgga gaagaagaac aggctcaggt ccacgggggc ggctcctccg
    10561 gcgaccgggc gagagtcgcg tgcggcgcgg cgaggctgcg gtcgagcacc gccagggccc
    10621 ggtcgatcag ggcgtcggcc cgcccccgta cgtcggccga cgccgggaac tggaacgtga
    10681 catgggtctg ctcgccgtca tcgatcatga cgtgcagggc gttgcgggcg accccgttga
    10741 acgccgacca gtccaccgtg gtggcgaggc cggcgaagac cgggccgggg gcgatccgcc
    10801 ggtagctgac cgagacggcg gcggtggcca ggaacggccg tgtcccgggc cggcacatcg
    10861 ccaacgggac cgtccggtgg gcgtacagct cccgcaggcc ggcgcggacg gtcgtcagcg
    10921 ccgccgcgta cgagccggtc ggtggcgtgg ggagggtgag cggaagctcg ttgacgtaca
    10981 tgccgatccg gtccgcctcg gccggcgtac gcaccgacag ctcgatcgcg atcgggacgg
    11041 gcccgtcgtc ccgggtgagg cagttggcga gcacggtgag cagcagctcg aaccgggtcg
    11101 cgtccagtgc gacggccgcc tcggccagcc tcgtacgggt ccggggggtc agcgcgcgga
    11161 cgaccgtgtc gccgggtcgt accccgccgt cgcggggcag ctcgaccggt cgcggggggt
    11221 tccgccacca gtattcggtg gccgcgacga ccaggtgctc cggcggcgtc cggtacccgg
    11281 gtccggccgg ctgcgccgcc accaccggcg gtgcgtcggg gccgtagcgg tcggccaggt
    11341 cccgcagcag gatgtccttg gactggccgt cgacgatcag gtggtgggcg gccaggacga
    11401 gcaccccgcc tccgttccgg agggggaacc accagacccg ggccagcggc ccggctgaca
    11461 ggtcgaaccg ggtgcggccg gcccgctcga cccgctcgcg gacggtcccg tcggcggtgg
    11521 gttcgaccgt gagcgtcagc gggtgctcgc cgaccgccag ccagggcagg ccgtcgaggt
    11581 tgtggcagcc ggcggtcagc agcgggtgcc gcgcggccag cgccgtacag gcccgcgcca
    11641 gccggcccac gtcgaccggg ccgcgcaggt gggcggtgac cgcgaccgtg tacgccgacc
    11701 cgagcgcggc cagctgctcg ttgaaccaga tgccccgttg cagcggcgag gtcggcacga
    11761 actgcgtcat ggtgacccgg acatccggtc ggcgatccag gcggcctgcg cggccaggcc
    11821 cggccgggcg tacagcgccg acaccggcgt ggcgaccgcg aactggtcgg agacgagacg
    11881 ggccagccgc agtgccgaca tcgagttgcc gcccagggcg aggaagtcgt cgtcgcggcc
    11941 cacggcggcc acgcccagca cgctcgccca gatgtcggcc agtcgtcgtt cgaccacggt
    12001 caccggggcg gcggcgggcg tcgatccggc cggcgggaag aggccccgca gcgaccgtgc
    12061 gaccaccttg ccgccgtcgt tgcgcggcaa cgcgtccaca cagacgaccc gctgcgggat
    12121 ctccggaccg gacagccggc cggcgaggaa ggcccgcagg tccgccggta cggcaccggt
    12181 acgggtcacc agcacggcgg cgggccgttc gccccacacc ggatcggcga cggcgaccac
    12241 cgcgcagtcc cggacgtcgg ggtgcccgtg cagcgcctgc tcgaccgcga acgacgagac
    12301 cttcgtaccg ccggagtgga tggtcgacgc gtcgcggccg gtgaggtgga ggtagccctc
    12361 gtcgtcgagc cggccccggt caccggtgcg ggtccaaccg tcgcggaacg tcgcggcgtc
    12421 accaccgtcg aggtaacggc gcggtggggc gtcggagccg atccagacct gacccacctc
    12481 gcgcgcagcg acctcccggc cggcgtcgtc ggtgatccgc acggcgcccc gaccgaccgc
    12541 gtccgggcgt cggctgtcga acaccatcgt cgtacgggcc ggtgcggcct cggtcgagct
    12601 gtaggtgttg acgatggtgg cgtacggcag gacgtcaccg agggcacgcg cgacggcggc
    12661 gggcagcacg tcgccggtcg ttcccacgag caccagcgac gacaggtcac gacggtcggg
    12721 ttcgccggag gccagcagct cccgggccat cgacgggacg aggaagaggg tgccgacccg
    12781 gaactcctcg acggcggcgc agacctcggc ggcgtcgaac cggggcacga cgagcgcggc
    12841 gggttcggcg gccaggccgg tgaggagcat ggtctgggcg gcgttcgtcc cgatggggaa
    12901 ggcgtgcagg aaatagcggg agtgcgcgag ttgccgccgg ccgggtgtgg tgtcgtgccc
    12961 gtgggtgagg ttgccgtggg tggcgacgac cgccctggcc gacccttcgg tccccgaggt
    13021 gaagatgatc tgggccgcgc cgtccggggt cgcccggtcg ggcacggcgt cggttgcggc
    13081 cccggccggc ccgcgctgcc agccgcccag ctccgcgggg acggcgcagc cttcccggat
    13141 gatcccgacc gccccggcga cggtgacccg cgcgacgagc tgtcccggcg ggagccgggc
    13201 cgacagcggt accgccaccc caccggcccg gagcacgcca cagaacgcgg tcgcgtaccc
    13261 gaaccactcc cgctcgtcga agagcagcgc cacccgctgg ccgacccgca gtccgtcgtc
    13321 ggcgagcgcg gcggcgagcg cgtccgccga ccggtcccac tgtgcgaacg tcagcgtcgc
    13381 gccgtcgagg tggcacaggg cgacggcgtc cggggtgtcc gccgcacgct gccgcagcag
    13441 gccgggcacg gttggtccgc cgctcatcgg gggtccggtg cccggccggc ggcgaccgcc
    13501 gcgatccgcc cgatcgtgcc ggcccgcacg atctcctcca gggcgagccg gatgcccagc
    13561 cgtcgctcga tccggaacgc gacctgggtg gtcagcagcg agtgccagcc cacgtcggtc
    13621 aggtcgtcgt ccaggccgac cccgtcgacg ccgaccagtt cctcgacgat ggcggcgatc
    13681 gcgtgctcgg tcggggtgtg cggcggtcgg gaccccgccg gcaccgccaa ccgccgccgg
    13741 tcgaccttcc cggcggcggt gagcggcagg gcgtccacca ccacgaccag gtccggcacc
    13801 aggtgggcgg ggacggcgcg ggccagggcc gcccgcagcg ccgtaccgga gggttggtag
    13861 cccggcgtcg atacgacgtg tgccacgagc gagaccgggc cggcgtccgc cgcgacggcg
    13921 gagacggccg ccgaccggac cccgggcagc cgcagcagcg cggcctcgac gccggccggc
    13981 tcgacccgga agccacggac cttcacctgc gcgtccatcc gaccgagcag gtggacgagg
    14041 ccgtcggcgt cccggcggcc ccggtccccg gtgcggtagg accggctgcc gtcgacctgc
    14101 ccgaaccgtg cggcggtgag ttcgggggcg ttgaggtagc cgcgggcgac gccacggccg
    14161 acgatgacga tctcgcccgg ctgcccgtcg gcgacgacct ggccgtcggg gtcgacgacg
    14221 aagatgtcgt atccggctat cggccggccg accgggatgc gctcgccgtc ggtgtccgcc
    14281 cggctgaccc ggtgcagggt gctggccacg gtggcctcgg tagggccgta gccgttgacc
    14341 agttcgcacc ggtcgatcca gcgccgcgcc gtggccggtg ccaacgggct gccgacgctg
    14401 agcatggtcc gtagccgggg gaggtcgtcc tccggcaggg agtcgagcac ggcggcgggc
    14461 agggccgcgt gggtgacggc ccgctccgcg agcagccgtg ccagcggcgc accgaccagt
    14521 gactcccggt cgacgacctc cagccgacag gcggcaccga gcccgaggag gagttcgaag
    14581 atccagccgt ccgccaccgg gccggcatag agcaggacgc gggcgtcgtc gccgaggtca
    14641 ccgaaccaac gccgctgcgc gaccatgagg ttgacgaccg cgtcgtggcc gatcatgacc
    14701 agcttcggcg tgccggtcgt gccggcggtg gggatgacgt aggccagccc ggtcgggtcg
    14761 ccggcagcgg gccggcctcc cggtcgcggt gacccggcgg ccggccgcgt cgggtccacc
    14821 tggcgcatgc cgggggcccg gtgcagcacg gacgtcgata cgagcaccgt ggcgtccgcc
    14881 gccgtcgcga ccgactggtt ccaggccggc gggctggccg gatcgagtgg cagcaggacg
    14941 cccccgctgc gccagatggc gagggccgcc gtgacgaggg gaacgccgcg ttccagggcg
    15001 accgccacca cggtcgcggg cccgacgccg gccccggaca gcgtgtcggc gagcacgtcc
    15061 gcccgctggt ccagatcggc gtacgtgacc gccccggtcc ggtcggccag ggccacccgg
    15121 tgcgggaacc ggcgggcgag tgtggacacc cggtcgctca ccgggacgaa gtccctgtcg
    15181 cgcaacggcg accccctcgt cgactcatct ggccatggac agggatctat ccgtgaggct
    15241 gtcacgacag tgcgggccgg tcaaggtgcc cgcgctgtcc ccgtggccgg ggcggtgcct
    15301 cccggtcgcc ggaccgcatc ccggcgcgct ctgcccagcg aaggcccggc ccttgacctc
    15361 acgtccggtg caggttgtcg gatgggggca tgcgtgcgat tcgcctccac cggttcggtc
    15421 ccgccaccaa tctcgtcctc gacgacctgc ccgacctcgc acccgccccc gggcaggtgc
    15481 gcatcgcggt agcggccagc ggggtccacc tgctcgacac cgcgctgcgc cggggcgagg
    15541 cgggcggccc gctgccactg ccggcgttgc cgaccgtgcc gggtcgcgag gtcgccggca
    15601 cggtcgacct ggtcggggcc ggggtggacg aggcgtggcg ggggcggcgg gtcgtcgccc
    15661 acctgggcat ggtccccggc gggtacgccg agcaggcggt caccgctgtc gagtcgctgc
    15721 acgtcgtacc ggaggggacg gggttcgccg acgcggtggc cctggtcggg acgggccgga
    15781 ccgccctcgg tgtcttcgag ttggcgccgc cgacggcgga cgacgtggtg ctggtgctgt
    15841 cggcggccgg tgggatgggc tggctgctgg tgcaggcggc ccggacggtc ggcgcgacgg
    15901 tggtcgccgc ggcccggggt gcccgacgca cggcccgggt cggtgagctg ggcgcggacg
    15961 tcgtggtggt cgactacgac cggccggact ggacggacct ggtccgggcg cgggtcggtg
    16021 ggccgaccct ggtgtacgac ggggtgggcg ggacactggg ccgggccgcc ctggagtcga
    16081 cggcgtcggg cggccggttc gtgatgttcg ggtggtcggc gggggaaccg acccgggtcg
    16141 gcacggcgga cctggtggag cgcagcctga ccgccggctg gctcgggcaa cggctgcgca
    16201 accggccggg cgggatcgcg gggctcgcgg cccggtcggt ggagctgggt ggtcgtggct
    16261 ggtggcagcc gctggtgtcg acatatccgc tggcggaggc ggccgccgcg cacgccgacc
    16321 tggaggggcg gcgggcgttg ggcaaggtgg tgctgaccgt cggcgggtga tccggggcgc
    16381 ggtctgcgcc accggtggcc gatgtgcgcc gtcgatgtca ccatgttcgt gggaaatgcg
    16441 ttccgcgtat tcgcccgcgc gggaaccccc gtactgctta cgctctcccg catcgacgag
    16501 cgtccgccgc ggtggcggcc ggcggtcgtc ggacccgagc gagggggcgg gtccgacgac
    16561 cggggacgcc gtcggttccg cccgcccggc cgtcgactgc cgtcccgggc ggtgacggtc
    16621 agccggggag ttgatcgacc cgggtgagca cctggtcgat caggccatac tcgcgggcct
    16681 gctcggcggt gaaccaccgg tcccggtccc agtcggcctg gatctcgtcg agggtgcgcc
    16741 cgctgtgctc ggcgatcaac tcctgcatgg tccgcttcac gtgcagcatg ttctccgcct
    16801 ggatggtgat gtcggcggcg gtgccaccaa tccccccgga cggctggtgc atcatcaccc
    16861 gcgcgtgcgg cagggcgaac cgcttgcccg ccgcccccgc gcagagcagg aactgcccca
    16921 tcgacccggc catccccaac gccagggtcg ccacgtcgtt gcggacgtac cgcatggtgt
    16981 cgtagacggc catgccggcg ctcaccgaac cacccggcga gttgatgtag aggtagatgt
    17041 cccgcttgct gtcctcggcg gcgagcagca ggatctgcgc gcagatctgg ttggccgagg
    17101 cgtcggtgac ctcggtgccc aggaagatga tccgttcccg cagcagccgc tcgaagacct
    17161 ggtcgccgaa ggccggctgc ccgccgtcca acatgcgcac gtcgtacccg atcatggtga
    17221 ccacctccgc gttgccggcg ggcgatttcg cgccgcccgg ggaccggcgg gtccagcctg
    17281 cgccgccggg cggccaccaa cccagggttt ctgcccccgg cagatccgcc ctcggcagaa
    17341 cccggccggc ctacccgacc agcagccgcc gtcggcccgc ccgggcccgt cgccgtgccg
    17401 gcaccctggg ggtacgcgca gcggggcggg cggtcgacac gacggcgatc acccggacgg
    17461 gcacggcgac ggtcaccgcc gcaaatccgg acgccccggc accgacgggc gacagcgccc
    17521 caccggcgag gacgacgccg tcaccgagcc gcagcatcgg cccgctgccg gtcggtcggc
    17581 cgaccacggc cctgggcggg ccgcacctcg ccgtggacgg accgaccgct gccgtgggac
    17641 gggcgaagcc ggccgtgggt ggaccgatct ggaggtgcgg gccactgccc gcgcggcggg
    17701 cggtcggcac ccggtccagc cgggcgaggc tcccgcccgg tggcacggga accccacgct
    17761 cgacccggcg caactcgtcg cgggcctctt cgagcaggtc ggacaggtgg attccgagtg
    17821 cccggcagat cgccgccagc acctcggagg aggcttcctt gcgcccgcgc tcgacctcgg
    17881 agaggtaggg cagggacacc ccggcggcgg cggccacctc gcgcagcgtg cggccctggc
    17941 gcagccgtac ccgacgaagc accccgccga tcacccgacg cagcagcgac atgcgggcct
    18001 cctcgtggcc ggtgtcccgg gaccctccca tcatgccccg tcgagggccc gggcaccggc
    18061 ccggccggcc actgcgcgtc gaccggaacg gtgggcacgc gggtccacca ccggccgggc
    18121 cgggtcacca ggtgccgacc ggggtggcgg gcccggggtg acggggcgct caccggcggt
    18181 gcggtcgacg gcccggcggg tcgacctgcc tggtaaccgc tatgttgtgc tcgtgcaggc
    18241 gacccggggt gagcaggacc gacggtgatc catttcccgg cgcagcggcg gggtccgctc
    18301 agcgcgttga gtctccgcct ggccgccgcc ctgggcctgg tcctgctgac cgtcgcggtg
    18361 gtctatctgg accgcagcgg ctaccgggac gtggacgaga acgggctgac cctgctcgac
    18421 tgcttctact acgccgtggt caccctctcc accaccgggt acggcgacat cacccccttc
    18481 gcgcagtcgg cccggctggt gaacgtcctg ttcatcaccc cggcccgggt gatcttcctg
    18541 atcatcctgg tcggcaccac cctggaagtc ctgaccgagc agtaccggac cggccgtcgg
    18601 ctggggcggt ggaggagaac cgtgaaggac cacgtcatca tctgcggcta cggcaccaag
    18661 ggccgcagcg cggtctccgc cctgctggag aacggactgg acaagtcccg gatcgtggtg
    18721 gtggagcgca acggcaccgc gctgcggcag gccacctcgg ccggactggt cgccatcgag
    18781 ggttccgcca cccggtcgtc ggtgctggag gaggcgcacg tccgcaacgc caaggccgtc
    18841 atcatcgcca ccgacagcga cgacgcctcg gtgctggtgg cgctgaccac ccggcagctc
    18901 accgccggtc aggtacggat catcgcggcc gtacgggagg ccgagaacgc cccgctgctg
    18961 cgccagagcg gcgcgcacca cgtgatcgtc tcctcggcca ccgccggtcg actgctcggc
    19021 ctctccacct ccgcgccgcc gctgatcgac gtggtggagg atctgctcac ccccgggcag
    19081 gggatggcgc tggcgatgcg ttccgccgag cggcacgagg tgggcaagtc cccacgtgag
    19141 ctggagtccc tggtcatcgc gctggtacgc cggggcaagg tggtcaccct ggcggacagg
    19201 gccggcgcgg tgatcgagac cggcgacatg ctcgtgcacg tccgcgacga ccgacccacc
    19261 gccaacacca ccgcctcctg acaccgggta gccgccgaaa cggcgagtgg ccggcccccg
    19321 gcatggggga acggccactt cggcgtgtcg acgggcgact agctgatggt ccaggtgtcg
    19381 ccggtggcga ggagggcggt gagttgttgt tcgggggtgt gggtggtggt ggctttggcg
    19441 gtggtgagtt gttgttggac gaggttgtcg taggaggggc ggtgggtttg ccggaatacg
    19501 ccgatggggg tgttgcggag gtctggtccg gggagtcggg atagtgcgaa ggcgtaggcg
    19561 gggtcggtga tggtggtgtc gtggatgacg atgtcgtcgg cgggggtggt ggcggtgtcg
    19621 cggacttcga ggccgaagcc gcgtggtggg tggacgatgc agtgttgtcc gttgtggccg
    19681 aaggtgatgg gttggccgtg ttcgaggggg atgaggtagt cgtcgcgggt gtcgggttgt
    19741 ttgagttgtt cgaaggcgcc gtcgttgaag atgttgcagt tttggtagat ctcgacgaat
    19801 gcggagcctt ggtgttgggc ggcggcgcgg aggactgatt ggaggtgttt gcggtcggag
    19861 tcgatggtgc gggcgacgaa ggtggcttcg gcgccgaggg cgagggagag ggggttgaag
    19921 ggggcgtctg cggagccggc gggggtggat ttggtgattt tgccggtttc gctggtgggg
    19981 gagtattggc ctttggtgag gccgtagatg cggttgttga agaggaggat tttgaggttg
    20041 acgttgcggc ggagggcgtg gatgaggtgg ttgccgccga tggagagggc gtcgccgtcg
    20101 ccggtgacga cccagacgga caggtcgggt cgggtgacgg acaggccggt ggcgatggcg
    20161 ggggcgcggc cgtggatgga gtg
//
