LOCUS       NZ_FMCU01000019        22131 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000019
VERSION     NZ_FMCU01000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23368
            Orig. end                         :: 45499
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22131
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12131]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12131
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            303..1166
                     /locus_tag="GA0070216_RS27310"
                     /old_locus_tag="GA0070216_11923"
     CDS             303..1166
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184936.1"
                     /locus_tag="GA0070216_RS27310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11923"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_091252052.1"
                     /transl_table=11
                     /translation="MTLNWQLTIAVLGGAAIGLGLFLLVREALPASPALGPALRRLHQP
                     PGTAVVAGRGPDWLGGFSRWLRPPHRQLALLDQTPEQYAMSILLSALVGLATPTVAGAL
                     LFLAGVSMPVVVPVLGSLGLALVCALLAHRTVLAKADTARDEFRAAVCTYLDLVALQLS
                     AAHGPVQSLERAAAVCDGWVFARIRESLRIAQMQMHSPWDELQELAEKIGIPELGDVGA
                     IMRSSGSEGAQVHETLRSRAESLRDQIRTDNLARAEGVTSRLDIPGSLLVFVLLAFVLY
                     PFIARL"
     gene            1196..1387
                     /locus_tag="GA0070216_RS27315"
                     /old_locus_tag="GA0070216_11924"
     CDS             1196..1387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283462.1"
                     /locus_tag="GA0070216_RS27315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11924"
                     /product="hypothetical protein"
                     /protein_id="WP_091252053.1"
                     /transl_table=11
                     /translation="MHLVTFLYVATVARLAELRREADRGDSPVPTAVIIAGLVTAGIAV
                     TGIVLTKAKGWMDGIPDK"
     gene            1384..1905
                     /locus_tag="GA0070216_RS35790"
                     /old_locus_tag="GA0070216_11925"
     CDS             1384..1905
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454398.1"
                     /locus_tag="GA0070216_RS35790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11925"
                     /product="TadE family protein"
                     /protein_id="WP_245722764.1"
                     /transl_table=11
                     /translation="MIRLPLTCARRDRAATTAQSRCEPLRAPEAGRRGPTGVRTAVRAA
                     RRRLTAGGTDRGANPVELAVVMPAVLVLLFGSIQIAAWFVARSTAMHAAQSGVNAQRVL
                     DAPAGAGEARARRFLGAAGDWLVGARTTCATTATEVTCTVTGKSLSVIPAVRFDVRQTA
                     HGTVERWTNP"
     gene            2061..2531
                     /locus_tag="GA0070216_RS27325"
                     /old_locus_tag="GA0070216_11926"
     CDS             2061..2531
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018587054.1"
                     /locus_tag="GA0070216_RS27325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11926"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_176739168.1"
                     /transl_table=11
                     /translation="MDRAAGRTRGSVSVEVAVLAPAFLALLMLAGVAGRVAVADEAVEA
                     AAHDAARAASIARDAGTAESAARTAARRQLDWRGLNCTSAPQVTVWGSTSNSDHTSLST
                     AFRRPLGEPVSIWVRVRCTVSFAGMRFPGLPMGDKRVEATFGSPLDRYRSRR"
     gene            2585..2959
                     /locus_tag="GA0070216_RS27330"
                     /old_locus_tag="GA0070216_11927"
     CDS             2585..2959
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785438.1"
                     /locus_tag="GA0070216_RS27330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11927"
                     /product="hypothetical protein"
                     /protein_id="WP_091252267.1"
                     /transl_table=11
                     /translation="MIGVLAIIGVAYDGAGQLRTLQRADDLAAEAARSGGQVIDRAAAI
                     EGRPKVIDEPGARAAVTQYLRGNSDVTGQQVSFPVVAGEKQKRVRVTVVYRRHMLGLIG
                     MDRTVTVSGEATARSLTDRP"
     misc_feature    2586..2606
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            3093..4412
                     /locus_tag="GA0070216_RS36245"
                     /old_locus_tag="GA0070216_11928"
     CDS             3093..4412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730902.1"
                     /locus_tag="GA0070216_RS36245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11928"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_091252055.1"
                     /transl_table=11
                     /translation="MTTSRGSTARRTGQLLTGFGSLVVLVALLVGAPVALLAFAGNPLP
                     DHLPTLTEVGAVLTSRDDGQLFIRALALVGWFGWATFAFSVLVEMGAQVTRRQTPRLPG
                     MSRQQRAAAALLGSVALILAASPAASAAVTLAQPLPAAAGTGVATTLDTSRTGLGAAPS
                     AGLGASAGVTHGAVPGSGLGPVPRTGFEDGKSTAKPVYRVARGDYLGEVAERYLDDFDR
                     YPEVARLNHLRDADRIRPGQVIKLPTEADDTGARRHASGHLVPGTPRKPSPRPPVTTPG
                     TPGGHADPQPGGPASPTTPGKPANPVAPATPKPTGKVGPATPQTATPQTAQPPAERPVG
                     VPPAMAAGASRATPDDAINRPLAVSAVLAVASIVGAQIGAVLGLRRRPARVVAGRTSAA
                     RIAAARMSTNRATTGRTPGRSMGSRASAARDLVTGRHRRD"
     gene            complement(4618..5457)
                     /locus_tag="GA0070216_RS27340"
                     /old_locus_tag="GA0070216_11929"
     CDS             complement(4618..5457)
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730901.1"
                     /locus_tag="GA0070216_RS27340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11929"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_245722765.1"
                     /transl_table=11
                     /translation="MTKLEQTAALDRVGDRLQRAVQATLRPQRVRDLLHGVFLGHPLHP
                     AMVQVPVGAWISAAVVDLLPGQRRAATTLVALGTVSAVPAAVAGLNDWAELSRDQRRVG
                     LVHAAANTVGLTLYAGSLAARLNGRHGVGRALAYLGLGAASAGAYLGGHLAYKQGAQVS
                     QSVSELHRMSDGWQSVAELAGLPQRKLVTREVDDVSVILYRHGDEVTVMLERCPHQSGP
                     LGEGEVQEIDGHACVVCPWHGSAFRLNGGEVVHGPSATDQQILPTRIVDGTLQTRLP"
     misc_feature    5727..5739
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     gene            <5786..5932
                     /locus_tag="GA0070216_RS35800"
                     /pseudo=""
     CDS             <5786..5932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007466288.1"
                     /locus_tag="GA0070216_RS35800"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="LDNQLQGQVVSDLDDLAAMMAAWENVRGEALSHWQSVDLIRKVAQ
                     TWN"
     gene            5923..6114
                     /locus_tag="GA0070216_RS27350"
                     /old_locus_tag="GA0070216_11930"
     CDS             5923..6114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287405.1"
                     /locus_tag="GA0070216_RS27350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11930"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_091252057.1"
                     /transl_table=11
                     /translation="MELNDARWRKSTRSSGNGGNCVEVADNLPGVIAVRDSKDPDGPTL
                     TFTPAAWHTFLTRITDRR"
     gene            6321..7076
                     /locus_tag="GA0070216_RS27355"
                     /old_locus_tag="GA0070216_11931"
     CDS             6321..7076
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (6-207). E-value: 2.4e-42. Score:
                     136.9. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS27355_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454388.1"
                     /locus_tag="GA0070216_RS27355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11931"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_091252059.1"
                     /transl_table=11
                     /translation="MAVHVSRDGAVTTVILDRAASRNAVDGPTARALADAFRAFEADPD
                     ARVAVLWGAGGTFCAGADLKAIGTPSGNRVEPDGDGPMGPTRMSLSKPVIAAISGYAVA
                     GGLELALWCDLRVAESDAVLGVFCRRWGVPLIDGGTVRLPRLIGEGRAMDLILTGRPVP
                     ADEAYAMGLVNRVVAPGEARAAAERLAAEIARHPQTCLRNDRASVLAGAGRPEPEALAT
                     EFAYGMDSLTADALAGAARFAAGAGRHGA"
     aSDomain        6339..6941
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS27355_ECH.1"
                     /evalue="2.40E-42"
                     /label="GA0070216_RS27355_ECH.1"
                     /locus_tag="GA0070216_RS27355"
                     /protein_end="207"
                     /protein_start="6"
                     /score="136.9"
                     /tool="antismash"
                     /translation="RDGAVTTVILDRAASRNAVDGPTARALADAFRAFEADPDARVAVL
                     WGAGGTFCAGADLKAIGTPSGNRVEPDGDGPMGPTRMSLSKPVIAAISGYAVAGGLELA
                     LWCDLRVAESDAVLGVFCRRWGVPLIDGGTVRLPRLIGEGRAMDLILTGRPVPADEAYA
                     MGLVNRVVAPGEARAAAERLAAEIARHPQTCLRNDRAS"
     misc_feature    complement(6340..6355)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(7110..8594)
                     /locus_tag="GA0070216_RS27360"
                     /old_locus_tag="GA0070216_11932"
     CDS             complement(7110..8594)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454372.1"
                     /locus_tag="GA0070216_RS27360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11932"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_091252061.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.9e-45, bitscore:
                     148.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPELVDVVVVGLGVGGEEVAGRLAEAGLTVVGVERDLVGGECP
                     YWGCIPSKMMIRAANALAEARRVDGLAGSAQVRADWAPVAKRIREEATDTWNDQAAVDR
                     FTGKGGRFLRGSGRLDGPDRVRVGDQVFQARRGIVLGTGTRPSIPPIEGLAGTPYWTNH
                     QAIEAAELPATLLIIGGGAIGLELAQVFARFGVGVTVLEASGRVLALEEPESSEVAAAA
                     LRADGVEIATEVRIERVGHDDGTFTVYAGDRSFSAEKLLVVTGRRAHLEELGLDTVGVD
                     GTQRYLPVDDRMHVTEGIWAVGDVTGEGAFTHIAMYQASIVVADVLDHARRAAGGPDAS
                     GTASVVGGAMGASSAVGGSMGAAGPSGAAGTVPRADYRALPRVTFTDPEVGAVGLTERQ
                     ARERGINVQVGFTELSSSTRGWIHKSEPGGFIKVIADADQGVLIGATSVGPAGGEVLSA
                     LVVAVHAAVPVSQLRHMIYAYPTFHRAIQSALNDLS"
     gene            complement(8682..10004)
                     /locus_tag="GA0070216_RS27365"
                     /old_locus_tag="GA0070216_11933"
     CDS             complement(8682..10004)
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283453.1"
                     /locus_tag="GA0070216_RS27365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11933"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_091252063.1"
                     /transl_table=11
                     /translation="MSGRTAVVLFTRDLRVHDHPALATACAAFDRVVPLYVLDPTLADH
                     SPNRTRFLHQCLAALRDTLRGLGGDLVIRRGDPVAEAIRVAREVGAEGIGLSADVSRYA
                     HRRERRLRAECDRHRLALRLFPGVTIVEPGALRPGGGDHYRVFTPYHRVWSGAQWRAEL
                     AAPRRVTLPDGVPVGRLPALPRGESPDAVVGGEAVGQRRLAQWSPTLHRYDDIHDDLAG
                     DETSRLSPYLRFGCLSPLAVANRADDRGSPFVRQLCWRDFYYQVTAAFPEISAKAYRRG
                     ATEDWRYDAAALTAWSEGRTGMPIVDAGMRQLHAEGWMHNRARLITAGYLTKVLGLDWR
                     PGLGVFSRWLLDGDVPNNSGNWQWVAGTGNDSRPYRGLNPVRQAERYDPDGGYVRRWVP
                     ELAAVAGKAVHQPWRLPPEVRRTLDYPPPLEVPDADPVWLR"
     gene            complement(10001..10912)
                     /locus_tag="GA0070216_RS27370"
                     /old_locus_tag="GA0070216_11934"
     CDS             complement(10001..10912)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018812108.1"
                     /locus_tag="GA0070216_RS27370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11934"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_091252065.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-114,
                     bitscore: 373.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2e-65,
                     bitscore: 214.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTDLTAAYARCQELHRHHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEDLPPAERAARLDAWGSRFVAGLHGEPVDDPLLPAVLHTIAVFDLDRTD
                     FASFLRSMAMDLTVLSYPTYDDLLDYMEGSAAVIGTMMLPILGSSDPVAAREPARQLGF
                     AFQLTNFIRDVAEDLDRGRTYLPDEDLAKFNVTPEDLRAAQATGRSTDRIRDLIEYEVT
                     RAQAHYAAAAPGVTLLAPASQACMRTAYALYGGILDEVAAQDYDVFVQRAVVPQRRRLS
                     VAAKALLARTGTPVVVPGPALT"
     misc_feature    10958..10976
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            10977..12131
                     /locus_tag="GA0070216_RS27375"
                     /old_locus_tag="GA0070216_11935"
     CDS             10977..12131
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="GA0070216_RS27375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11935"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_091252067.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.6e-48, bitscore:
                     156.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAGNALRVAPAQPGATDDPVHGVLVAFARDLVNDVDDTLS
                     AFLTREVDALTEIDAAMGGFAATARESVLAGGKRVRPTFAYWGWRGVVGGDAPLPTVLP
                     ALAALELLHTFALVHDDVMDASDTRRGLPTVHRAAAARHVTAGHTGDPSRFGESVAVLI
                     GDLCLVWADRLLAHATVPPARLLEVRRCYDQMRIETIAGQYLDVLGENDAANWSVDQAL
                     RVARYKTASYTVQRPLLFGASLAGIAPDAPLIAAYTRYGLAVGEAFQLRDDLLGVYGDP
                     AATGKPAGDDLRTGKPTVLLMLARQLATGGQRRALERAGTAVGVREVARLADIVADTGA
                     VGRVEHMISDRVADALAALGTASIDETARTALTGLATAATTRRA"
     gene            12160..13641
                     /gene="crtI"
                     /locus_tag="GA0070216_RS27380"
                     /old_locus_tag="GA0070216_11936"
     CDS             12160..13641
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454362.1"
                     /locus_tag="GA0070216_RS27380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11936"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_091252069.1"
                     /sec_met_domain="DAO (E-value: 1.3e-19, bitscore: 64.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGRTDRVVVVGAGLGGLACALHLAGSGRQVTVLEREPVPGG
                     RAGRLSVDGYEFDTGPTVLTMPDLIAEALGAVGEELSDWLDLTPIDPAYRAYYPDGSTL
                     DVITDTTRMAAEISRVCGPREADGYLRFVDYARNLWNWERADFIDRNLDAPTDLLTGNL
                     LKLLASGAFRRLQTKINQFFSDPRTQRIFSFQAMYAGLSPHDALAIYSVIAYLDSVAGV
                     YFPRGGIHAVSRGMAGAAEKHGVQIRYDTTVTRVETANGRATGVVTADGELVPADVVVL
                     NPDLPVAYRDLLPGGRQRKLTYSPSCVVLHIGSTQGYGKIAHHNIHFGRAWKGTFDEVI
                     GRGELMSDPSLLVTNPSRTDPSVAPDGRHTYYVLAPVPNLDRAPFDWRGDLSRRYADQL
                     VATLEERGYVGFGAGIEVLRTITPAEWEEQGMAAGTPFAAAHTLFQTGPFRPSNLHRSL
                     PNVVFTGSGTQPGVGVPMVLISGKLAANRITGAGR"
     gene            13646..14320
                     /gene="idi"
                     /locus_tag="GA0070216_RS27385"
                     /old_locus_tag="GA0070216_11937"
     CDS             13646..14320
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074008.1"
                     /locus_tag="GA0070216_RS27385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11937"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_091252071.1"
                     /transl_table=11
                     /translation="MKSREGHLVELVDDTGRVLGEATVAAAHQAPGRLHRAFSVLLVDP
                     DGRVLLQQRAPVKTRFPLRWANSCCGHPLPGESLAEAANRRLTEELGAGPVSLTEVGVY
                     LYYAEDPTTGRVEFEYDHVLRADVPTGLTLLPDPDEVSELRWADPTRAMAEIDTDPRSY
                     APWLGGVLSRLLRPTPTGPTADPTLATATAGPTTPPGAHAAGSATPSGRRVDDVSERSG
                     GR"
     gene            14310..15248
                     /locus_tag="GA0070216_RS27390"
                     /old_locus_tag="GA0070216_11938"
     CDS             14310..15248
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283448.1"
                     /locus_tag="GA0070216_RS27390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11938"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_091252073.1"
                     /transl_table=11
                     /translation="MVDEPLSAGAVARRLGVAVTTLRTWHQRYGLGPSQHIPGHHRRYT
                     PADLARLEIMRKLTAEGVTPAEAARWAKQSPGVAVRLPARTGRDGGGQTIPVGRAGPAA
                     RGLARAAMRLDAAVIGDTISHALATDGVIATWEGLLRPVLAGIGERYVATAGLIDVEHL
                     MSRCVSEAFAAVAHSGRAAGPARILLSCADEEQHTLPLEALAAALAEAGVAYRMLGARV
                     PVAALVEAVNRTGPAAVVVWSHTRLTADPGQLSALLAVPRRPLLVLAAGPGWRADTLPA
                     GVVRPVDLAEAVSLALAVRDSLDQSTGADRA"
     gene            15313..16101
                     /locus_tag="GA0070216_RS27395"
                     /old_locus_tag="GA0070216_11939"
     CDS             15313..16101
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473455.1"
                     /locus_tag="GA0070216_RS27395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11939"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_091252271.1"
                     /transl_table=11
                     /translation="MRSRPVLAVALGLLLLVAGCGDQPRHVRPAAAPVPTTSAPEPTRT
                     PAATPPPTSKPKPRLRPKPKTLPAGLRKATGVRAVALTFDDGPDPTWTPRVLNQLRAAK
                     VKATFCVVGTQVRKHPELVARIVREGHQLCNHSWHHDVDLGRRPVAEIRADLVRTNQAI
                     TKAVPGAKVPFYRQPGGRWTPEVVAVAKELGMRALHWTVDPQDWAKPTAGVITGRVEGA
                     ARPGAVVLMHDGGGDRSRTVGAVPHVIGDLKRRFGIAPPR"
     misc_feature    16158..16171
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     tRNA            16245..16317
                     /anticodon=(pos:39647..39649,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0070216_RS27400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0070216_11940"
                     /product="tRNA-Glu"
     gene            16245..16317
                     /locus_tag="GA0070216_RS27400"
                     /old_locus_tag="GA0070216_11940"
     tRNA            16350..16426
                     /anticodon=(pos:39752..39754,aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0070216_RS27405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0070216_11941"
                     /product="tRNA-Asp"
     gene            16350..16426
                     /locus_tag="GA0070216_RS27405"
                     /old_locus_tag="GA0070216_11941"
     tRNA            16529..16602
                     /anticodon=(pos:39931..39933,aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0070216_RS27410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0070216_11942"
                     /product="tRNA-Phe"
     gene            16529..16602
                     /locus_tag="GA0070216_RS27410"
                     /old_locus_tag="GA0070216_11942"
     misc_feature    complement(16650..16661)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            16816..17340
                     /locus_tag="GA0070216_RS27415"
                     /old_locus_tag="GA0070216_11943"
     CDS             16816..17340
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018727996.1"
                     /locus_tag="GA0070216_RS27415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11943"
                     /product="SRPBCC family protein"
                     /protein_id="WP_091252075.1"
                     /transl_table=11
                     /translation="MGQENANPEDVQQDVDRYSLRSTLLVPATAEQAFAVFTGSLADWW
                     VREYTWSGPAALAELGMEPRAGGMLYEIGPYGFRGDWGRVLTWDPPRRLVFTWQLGPDR
                     LPVPDPARASEVEVLFLPDESGHTRIELEHRHFDRHGEAAEGYREALTAGWHELLGRYL
                     ATLTGTAPGPH"
     gene            complement(17364..18080)
                     /locus_tag="GA0070216_RS27420"
                     /old_locus_tag="GA0070216_11944"
     CDS             complement(17364..18080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074004.1"
                     /locus_tag="GA0070216_RS27420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11944"
                     /product="DUF2786 domain-containing protein"
                     /protein_id="WP_091252077.1"
                     /transl_table=11
                     /translation="MSEAMLSKVRKLLAQAEDAACTPAEAAAFTAKATELIARYGVDRA
                     LLAARDPTTDPVGDRVVDVVAPYARDKAGLLAAVADPLRCRCVRRPAGSGFALHLFGFA
                     SDLERVDLLFTSLLVQAAHGLAGTVVPPGEHPAAFRRSWLAGFARVISDRLRVAEADAV
                     AQRDTSSVALVLADRSDRVARRVTEVYPRLRTTPIRRLAGSGFGAGAAAGHRADLGGTD
                     AVDAPTTRAHRGLPTR"
     misc_feature    complement(18132..18146)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            18207..18620
                     /locus_tag="GA0070216_RS27425"
                     /old_locus_tag="GA0070216_11945"
     CDS             18207..18620
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS27425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_11945"
                     /product="hypothetical protein"
                     /protein_id="WP_091252079.1"
                     /transl_table=11
                     /translation="MASRTARLAALAATLPLLWHGAPAQAAPETNLSASAATCYGGAVR
                     SYFQAGGWGGDAGPYKASARCKDVNVKNSSAFGTEACVVFIDKTNSCNYLTYLPAKSDW
                     ITVATNVRDGANFKVRFTNLRYEYEPLVAYHAY"
     gene            complement(18658..19044)
                     /locus_tag="GA0070216_RS27430"
                     /old_locus_tag="GA0070216_11946"
     CDS             complement(18658..19044)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454347.1"
                     /locus_tag="GA0070216_RS27430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11946"
                     /product="hypothetical protein"
                     /protein_id="WP_091252273.1"
                     /transl_table=11
                     /translation="MTDVPDQTLADATAVLHSALSGDGAAVVGTFDAVVDRSGLAGAYT
                     VAWTLAATMVGDPPPGACALDFPGIDDAGYDTRWVARFVSAYANHDADTGEALFGAAVA
                     DGQLPDCLLTLAGSTVATLRSRAG"
     gene            19228..20580
                     /locus_tag="GA0070216_RS27435"
                     /old_locus_tag="GA0070216_11947"
     CDS             19228..20580
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011904086.1"
                     /locus_tag="GA0070216_RS27435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11947"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_091252082.1"
                     /transl_table=11
                     /translation="MLVTRGPRPAILAACASFLLVISACGTTDKPEEAATPQVRLYGTD
                     GNMLNSFAAELKDRADLVDGMKGTTPLTPLTDDFKQRLRSVDPKLTDYLYAAESYDAVM
                     ISALAAQLAGSTDPADIAKQIVGVTTNGQRCTDAASCLPLARDAQDIEYRGQSLTRAGF
                     TDIGEPATASYATLHFDNQKINDAKTEFVGAGDESGVSTKAAPKPKKQRGGRNDSSDGS
                     PLILGGLLPKTGDLALANPPLAAGVALALKEINAAGGVLGDPVVWIDGDDGTNPAVAKA
                     TVASHVKDKVHVIIGAAASGISSAVLPDVVAAGKILFSPSNTDSGLSQADDKGLYFRTA
                     PPDSLQGRALADVILRDGPHKIVVVARKDSYGEGLQETVRAELERAGFGNDRVKLFTYD
                     PPADAKAPPVDFGNLAGDIKGYRPEAVLVIGFGESAGLIKALADAGVPIRH"
     gene            complement(20633..21376)
                     /locus_tag="GA0070216_RS27440"
                     /old_locus_tag="GA0070216_11948"
     CDS             complement(20633..21376)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (12-224). E-value: 3.4e-52. Score:
                     169.1. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS27440_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454342.1"
                     /locus_tag="GA0070216_RS27440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_11948"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_091252085.1"
                     /transl_table=11
                     /translation="MSGLRVEELPDRVVVTLDRPEKRNAIDADLIGALHDVCAALEARP
                     RLLLLTGGADGLFAGGADIGQLRERGRLDALAAINSAAFARLRALPMPSVAAVDGPALG
                     GGAELAYACDLRVCTSRAVFGQPEVRLGILAGAGATHRLPALIGEGRAKELLFTGRRVD
                     ADEALRIGLVNRVVAEPAELLPTAHGLLDEMAEGSALALRLTKLAVDAPAAAHPQLDLV
                     SQAVLFEDEEKHRRMTDFLERRRPR"
     aSDomain        complement(20705..21340)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS27440_ECH.1"
                     /evalue="3.40E-52"
                     /label="GA0070216_RS27440_ECH.1"
                     /locus_tag="GA0070216_RS27440"
                     /protein_end="224"
                     /protein_start="12"
                     /score="169.1"
                     /tool="antismash"
                     /translation="VVVTLDRPEKRNAIDADLIGALHDVCAALEARPRLLLLTGGADGL
                     FAGGADIGQLRERGRLDALAAINSAAFARLRALPMPSVAAVDGPALGGGAELAYACDLR
                     VCTSRAVFGQPEVRLGILAGAGATHRLPALIGEGRAKELLFTGRRVDADEALRIGLVNR
                     VVAEPAELLPTAHGLLDEMAEGSALALRLTKLAVDAPAAAHPQLDLVSQ"
     misc_feature    complement(22010..22023)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.31"
                     /tool="antismash"
ORIGIN
        1 gacgtgctcg gctcgatcgc ctcggccgcc tccgccgagg tggctacccg gcgtgaggtg
       61 gaggccaaac gcacccagcc ccggttcgcg gtccgcttcc tcaccgggat gaccctggcc
      121 gtgctggcgt acgggttggt caacaccgag tacgtccggc cgtacgggac gttcttcggt
      181 caggtgctga tggcgacgct cgcgacggcg ttcatcgccc tgctggtgtg ggtacgcgcg
      241 atgagccagc ccccgccgcc gccccggttc ctgcccaggc ccgacccggc ggagctggtc
      301 gcatgacgct caactggcag ctcaccatcg cggtgctcgg cggggccgcc atcgggctcg
      361 gcctgttcct gctggtccgg gaggcgttgc cggcctcccc ggcgctcggc cccgcgctgc
      421 gccggctgca ccaaccgccg ggcaccgccg tcgtcgccgg gcgggggccg gactggttgg
      481 gtggcttctc ccgctggctg cgcccgccgc accgtcagct cgccctgctc gaccagaccc
      541 ccgagcagta cgccatgtcg atcctgctct ccgccctggt cgggctggcc accccgacgg
      601 tggcgggggc gctgctcttc ctggccgggg tgagcatgcc ggtggtcgta ccggtgctgg
      661 gcagtctggg gttggcgctg gtctgcgcgc tgctcgcgca ccgcacggtg ctggccaagg
      721 cggacaccgc ccgggatgag ttccgcgcgg cggtctgcac ctacctggat ctggtggcgt
      781 tgcaactgtc ggcggcgcac ggcccggtgc agtcgctgga acgcgcggcg gccgtctgcg
      841 acggctgggt cttcgcccgc atccgggagt cgctgcggat cgcccagatg cagatgcact
      901 cgccctggga cgagttgcag gaactggccg agaagatcgg catcccggag ctgggtgacg
      961 tcggagcgat catgcggtcc tccggcagcg agggcgccca ggtgcacgag acgctgcgca
     1021 gccgcgccga gtcgctccgg gaccagatcc gcaccgacaa cctggcccgc gccgagggcg
     1081 tcaccagccg gctggacatt cccggctcgc tgctggtctt cgtgctgctg gcgttcgtcc
     1141 tctatccgtt catcgcccgc ctctgagcaa cccaccccga gaaggagccc tccccatgca
     1201 cctcgtcacc ttcctctacg tcgccacagt ggctcggctg gccgagctac gccgggaggc
     1261 ggatcggggc gacagcccgg tcccgaccgc cgtgatcatc gccggcctgg tcaccgccgg
     1321 catcgcggtc accggcattg tgttgaccaa ggccaagggc tggatggacg gcatcccgga
     1381 caagtgatcc gccttcccct gacctgcgca cgccgggacc gggcggccac caccgcccag
     1441 tcccggtgcg agcccctgcg cgcgcccgag gccgggcgtc gcggccccac cggggtccga
     1501 accgccgtcc gggccgcccg tcgcaggctc accgccgggg gtacggaccg gggggccaac
     1561 cccgtggagc tggccgtggt gatgccggcg gtgctggtgc tgctcttcgg ctccatccag
     1621 atcgccgcct ggttcgtggc ccggtcgacg gcgatgcacg ccgcccagag cggggtgaac
     1681 gcgcagcggg tcctcgacgc tccggcgggg gcgggtgagg cccgcgccag gcgtttcctc
     1741 ggtgccgccg gggactggct ggtcggggcg aggaccacct gcgccaccac cgccaccgag
     1801 gtgacctgca cggtcaccgg caagtccctg agcgtcatcc cggccgtccg gttcgacgtc
     1861 cggcagaccg cccacggcac cgtcgaacgg tggaccaacc cgtgaccgcc cacccgcccc
     1921 ggcgcaccgg gcgcgacgtg ctgacccggc tcgcccgagg acgtgcccgg ggcgaccggg
     1981 ccgtcgtcca ccccccgcga tccggcagcc ccgacggggt ggtcgggcag gccgccgggc
     2041 gtcacccggg cgacatgtcg gtggaccggg cggcggggcg tacccgggga tcggtgtcgg
     2101 tggaggtggc ggtgctggcc cccgcgttcc tcgcgttgct gatgctggcc ggggtggccg
     2161 gccgggtcgc cgtggccgac gaggcggtgg aggcggcggc gcacgacgcc gcgcgggccg
     2221 cctcgatcgc ccgcgatgcc ggcacggcgg agagcgccgc ccggacggcc gcccgccggc
     2281 agctcgactg gcgcggcctc aactgcacga gcgcacccca ggtcacggtc tgggggtcga
     2341 ccagcaactc cgaccacacg tcgttgagca cggcgttccg gcggccgctc ggcgagccgg
     2401 tgagcatctg ggtccgggtg cgctgcacgg tctccttcgc cggcatgcgc ttccccgggc
     2461 tgccgatggg cgacaaacgg gtcgaggcca ccttcggctc cccgctggac cgttaccgga
     2521 gccggcggtg accgcgcgtc cgaccggcga cgagggccgg atcagcctct tcctcgccgt
     2581 caccatgatc ggcgtcctgg cgatcatcgg cgtcgcctac gacggcgcgg gtcaactgcg
     2641 taccctgcaa cgcgccgacg acctggccgc cgaggcggcc cgcagcggcg ggcaggtgat
     2701 cgaccgggcc gccgcgatcg aggggcgacc caaggtgatc gacgagccgg gcgcccgcgc
     2761 ggccgtcacc caatacctgc ggggcaactc cgacgtgacc ggccagcagg tcagtttccc
     2821 ggtggtcgcc ggagagaaac agaaacgggt acgggtcacc gtcgtctacc gccggcacat
     2881 gctcggcctg atcggcatgg accgcaccgt caccgtctcc ggcgaggcga ccgcacgctc
     2941 cctcaccgac cgcccatgag cccgctgacc tggcggattc cgtctgttgc gcacccagac
     3001 cgtcggcccg ctcacccggt acccccacac cgagaccgta ggcccactca tccggtgtcc
     3061 ccgcaccggc agaccgtagg aaggagggca gcatgaccac atcgcgtggt tccaccgccc
     3121 gacgtaccgg gcagttgctc accggcttcg gatcgctggt ggtactggtg gcgttgctgg
     3181 tcggcgcacc ggtcgccctg ctcgccttcg ccggcaaccc gctgccggac cacctgccca
     3241 ccctcaccga ggtcggcgcc gtgctgacca gtcgggacga cggccagctc ttcatccggg
     3301 cactggcgct ggtcggctgg ttcggctggg cgacgttcgc cttctcggtg ctggtggaga
     3361 tgggtgccca ggtcacccgc cgacagacgc cccggctgcc cgggatgagc cggcagcagc
     3421 gggcggcggc ggccctgctg ggctcggtcg cgctgatcct cgcggccagt ccggcggcga
     3481 gcgcggcggt gacgctggcc cagccgctcc cggccgccgc cggcaccggc gtggcgacca
     3541 cgctggacac ctcccgcacc gggctcggcg ccgcccccag cgccggcctc ggtgccagcg
     3601 ccggtgtcac ccacggcgcg gtccccggtt ccggcctcgg tcccgtcccc cggaccggct
     3661 tcgaggacgg gaagtcgacg gcgaagccgg tgtaccgggt ggcccggggt gactacctgg
     3721 gtgaggtggc cgagcgctac ctggacgact tcgaccgcta tcccgaggtc gcccggctca
     3781 accacctgcg cgacgccgac cggatccggc cgggtcaggt catcaagctc cccaccgagg
     3841 ccgacgacac cggtgcccgc cggcacgcca gtggccacct ggtcccgggt acgccccgca
     3901 agccgtcccc gcgcccgccg gtcaccacgc cgggcacccc cggcggccat gccgacccgc
     3961 agccgggcgg tccggcctcg ccgaccaccc cgggcaagcc cgccaacccg gtggcccccg
     4021 ccaccccgaa accgaccgga aaggtcgggc cggccacccc gcagaccgcc accccgcaaa
     4081 ccgcccagcc cccggccgag cgacccgtcg gggtgccacc ggcgatggcc gccggagcgt
     4141 cccgggccac cccggacgac gcgatcaacc ggccgctggc cgtctcggcg gtactggcgg
     4201 tggcgagcat cgtcggcgcg cagatcggcg cggtactcgg cctgcgccgc cgccccgcac
     4261 gggtggtggc cggccgcacc tcggccgccc ggatcgccgc cgcccgcatg tccaccaacc
     4321 gcgccaccac cggccgcacc ccgggccgct ccatgggcag ccgcgcctcc gccgcccgcg
     4381 acctggtaac cggccgccac cgccgcgact gacccccacc cacactcctc gccccgtccc
     4441 gccgccctgc cccacccggc cgacccaacc cggccttacc cgccccgccc ccggccgccc
     4501 cgccccggac ggctcgcccg gttgatcaag aggtttgcgt caaagttgat ctccagtttg
     4561 ccgcaaacct cttgatcaac gctttagggc gagacgagac gggcgagacg ggtggggtta
     4621 ggggaggcgg gtttggaggg tgccgtcgac tatccgggtg gggaggatct gctggtcggt
     4681 ggcggagggg ccgtgcacta cctcgccacc gttgagtcgg aacgccgagc cgtgccaggg
     4741 gcagaccaca caggcgtgcc cgtcgatctc ctgcacctca ccctcaccga gcgggccgct
     4801 ctggtgcggg cagcgctcca acatcacggt gacctcgtcg ccgtgccggt agagaatgac
     4861 cgagacgtcg tccacctcgc gggtcaccag ctttcgctgc ggcagccccg ccagctcggc
     4921 caccgactgc catccgtcgc tcatccggtg cagttcggag acgctctggc tgacctgcgc
     4981 cccctgcttg tacgccagat gcccaccgag gtacgccccg gcgctcgccg cgcccagccc
     5041 cagataggcc agcgcccggc cgacgccgtg tcggccgttc aatcgggcgg cgagggagcc
     5101 ggcgtacagg gtgaggccca cggtgttggc ggcggcgtgg acgagcccca cccgacgctg
     5161 gtcccgggac agctccgccc agtcgttgag cccggccacg gcggcgggta ccgcgctcac
     5221 ggtgcccagc gcgaccagcg tggtggccgc gcggcgctgg ccggggagca ggtcgaccac
     5281 tgccgcgctg atccaggcgc ccaccggcac ctgcaccatc gcggggtgca gcgggtggcc
     5341 cagaaagacg ccgtgcagca ggtcacgtac ccgctgcggg cggagggtcg cctggacggc
     5401 gcgctgcaac cggtcgccta cccggtccag cgcggcggtc tgttcgagtt tcgtcatcaa
     5461 cgctcgcacg ttcaccgact tcccggccga accggcggca aaccgggcag tcggcaccac
     5521 ttcgggttcc ccggcttgat tgactcaacg gcggccaggt agcggtatcc acccagcccg
     5581 gactccgcaa catcccgcca ccagcgtcct ccggcggcgg acccggagag gctgcaccga
     5641 tcagcgccgg tacgcggacg cggacgccac cagcgccacg atctccgggg cgggcgggtc
     5701 tcgggccggg gcgggcgggt ctcggggtgc cggtgtcaca ccgcgccgtc cgatcctcgc
     5761 gcccgggccc agccgaggaa acgacctcga caaccaactc cagggacagg tagttagcga
     5821 tctcgatgac ctcgcggcca tgatggcagc gtgggagaac gtgcgcggcg aagcgctgtc
     5881 ccactggcag tccgttgatc tgatcagaaa ggtggcccag acatggaact gaacgacgca
     5941 cgctggcgca agagcacccg cagcagcggc aacggcggaa actgtgtcga ggtggccgac
     6001 aacctgcccg gagtcatcgc cgtccgcgac tccaaggacc ccgacggccc caccctgacc
     6061 ttcacccctg ccgcctggca caccttcctc acccggatca ccgaccgccg ctgaccccgc
     6121 cccgcccgcc gtgccaccgg gtcgcaccgg ccgggccacg ccccggcact acccgcccac
     6181 ggagatcccc tcaatgtcgc gcagatagcg gtatcaagcc cccggaaccc cgcaacatcg
     6241 cccccacagc gccacccgca agcccgcgca gcgggcgggg cgggctgggc ggtcggggct
     6301 gggcggggga tgctgggggg atggccgtac atgtttcccg ggacggggcg gtgaccacgg
     6361 tgatcctcga ccgggcggcg tcgcgcaacg ccgtcgacgg cccgaccgcg cgggcgctcg
     6421 ccgacgcgtt ccgcgcgttc gaggccgacc cggacgcccg ggtcgcggtg ctgtggggcg
     6481 cggggggcac gttctgcgcg ggtgccgacc tcaaggccat cggcaccccc agcggcaacc
     6541 gggtcgagcc cgacggcgac ggcccgatgg gtcccacccg gatgtcactg tccaagccgg
     6601 tcatcgcggc gatctccggg tacgcggtgg ccggcggcct ggagctggcg ctctggtgcg
     6661 atctgcgggt cgccgagtcg gacgcggtgc tcggggtgtt ctgccgacgt tggggggtgc
     6721 cgctgatcga cggtggcacc gtacggctgc cccggctcat cggcgagggc cgggcgatgg
     6781 acctgatcct caccggccgt ccggtgcccg ccgacgaggc ctacgcgatg gggctggtca
     6841 accgggtggt cgcgccgggt gaggcacggg cggcggccga gcggctggcc gccgagatcg
     6901 cccgccatcc gcagacctgc ctgcgcaacg accgggcgtc ggtgctggcc ggcgccggcc
     6961 ggcccgagcc ggaggcgctc gccaccgagt tcgcctacgg gatggactcg ctcacggccg
     7021 acgcgctggc cggcgcggcc cgcttcgccg ccggcgccgg ccggcacggc gcatgaaccg
     7081 cgccggccgg cacggagagt gagccgggtt cagctcaggt cgttcagggc gctctggatg
     7141 gcccggtgga acgtcgggta cgcatagatc atgtgccgga gctggctgac cgggacggcc
     7201 gcgtgcaccg cgacgaccag cgccgagagc acttccccac cggccgggcc gaccgaggtc
     7261 gcgccgatca gcaccccctg gtcggcgtcg gcgatcacct tgatgaagcc gcccggctcg
     7321 ctcttgtgga tccagccccg ggtggacgac gacagctcgg tgaagccgac ctgcacgttg
     7381 atgccccgct cgcgggcctg ccgttcggtg agcccgaccg cgcccacctc cgggtcggtg
     7441 aaggtgaccc ggggcagcgc ccggtagtcg gcgcggggga cggtgccggc ggcgccgctc
     7501 gggccggccg cgcccatcga ccccccgacc gcgctggaag cgcccatcgc accgcccacc
     7561 acgctggcgg tgccgctggc gtcgggaccg ccagcggcgc gccgggcatg atcgagcaca
     7621 tcggcgacca cgatcgacgc ctggtacatg gcgatgtggg tgaacgcgcc ctcgccggtc
     7681 acgtcgccga ccgcccagat cccctcggtg acgtgcatcc ggtcgtccac cggcaggtag
     7741 cgctgggtgc cgtccacccc gacggtgtcc aaccccaact cttccaggtg ggcccggcga
     7801 ccggtcacca ccagcagctt ctcggcgctg aacgaccggt caccggcgta cacggtgaag
     7861 gtgccgtcgt cgtggccgac gcgttcgatc ctgacctcgg tggcgatctc caccccgtcg
     7921 gcgcgcagcg cggcggcggc cacctcggac gactccggct cctccagggc gagcacccgg
     7981 ccggacgcct ccagcacggt caccccgacc ccgaaccggg caaaaacctg cgccagctcc
     8041 agcccgatcg cgccgccccc gatgatcagc agggtcgccg gcagctccgc cgcctcgatc
     8101 gcctggtggt tcgtccagta cggggtgccg gccagccctt cgatcggtgg gatcgacggg
     8161 cgggtgccgg tgccgaggac gatgccccgc cgggcctgga acacctggtc accgacccgg
     8221 acccgatcgg ggccgtcgag ccggccgctg ccgcgcagga accgcccacc cttgccggtg
     8281 aaccggtcca ccgcggcctg gtcgttccag gtgtcggtgg cctcctcccg gatgcgtttc
     8341 gccaccggcg cccagtcggc ccggacctgc gccgagccgg ccaacccgtc gacccgtcgg
     8401 gcctcggcca gggcgttcgc cgccctgatc atcatcttgc tggggataca gccccagtac
     8461 gggcactccc cgccgaccag gtcccgttcg acgccgacga cggtgagtcc ggcctcggcg
     8521 agccgcccgg ccacctcctc gccgcccacg ccgagcccga ccacgaccac gtccaccagt
     8581 tccggctctg ccatcccgcc agcattccgc acggccccgc ccccggccac cgctccaccc
     8641 cggaattccc gcccccgtgc accggaccgc ccgccggtgg gtcagcgcag ccagaccggg
     8701 tcggcgtcgg ggacctccag cggcggcggg tagtcgaggg tgcggcgcac ctcggggggc
     8761 agccgccacg gctggtgcac ggccttgccg gccaccgccg ccagctcggg cacccagcgg
     8821 cggacgtacc cgccgtcggg gtcgtagcgt tcggcctggc gtaccgggtt gagtccccgg
     8881 taggggcggc tgtcgttgcc ggtgccggcc acccactgcc agttgccgga gttgttgggc
     8941 acgtccccgt cgagcagcca gcgggagaag accccgaggc cgggccgcca gtccaggccg
     9001 agcaccttgg tcaggtagcc ggcggtgatc agccgggccc ggttgtgcat ccacccctcg
     9061 gcgtgcagtt gacgcatacc ggcgtccacg atcggcatcc cggtccggcc ctcgctccag
     9121 gcggtcagcg ccgccgcgtc gtaccgccag tcctcggtgg ccccacgccg gtaggccttg
     9181 gccgagatct ccgggaaggc ggcggtgacc tggtagtaga agtcccgcca gcagagctgc
     9241 cggacgaacg ggctcccccg gtcgtcggcc cggttcgcca ccgcaagcgg ggacagacag
     9301 ccgaaccgca ggtaggggct gagccgggag gtctcgtcgc cggccaggtc gtcgtggatg
     9361 tcgtcgtacc ggtgcagggt cggcgaccac tgtgcgagcc ggcgctgccc gacggcctcg
     9421 ccgccgacca cggcgtccgg cgactcgccc ctgggcagtg ccggcagccg accgaccggg
     9481 accccgtcgg gcagggtgac ccgccggggc gcggccagct ccgcccgcca ctgcgccccc
     9541 gaccagaccc ggtggtacgg ggtgaagacc cggtagtggt cgccgccgcc gggccgcagc
     9601 gcccccggct cgacgatcgt gacgccgggg aagagccgca gggcgagccg gtgccggtcg
     9661 cactcggcgc gcagccggcg ttcccggcgg tgggcgtagc ggctgacgtc ggcggacagg
     9721 ccgatcccct cggcacccac ctcccgggcc acccggatcg cctcggccac cgggtcgccc
     9781 cggcggatca ccaggtcacc gccgagcccg cgcagggtgt cccgcagcgc ggcgaggcac
     9841 tggtgcagga accgggtgcg gttgggcgag tggtcggcca gcgtcgggtc gaggacgtac
     9901 agcggcacca cccggtcgaa ggcggcgcag gccgtcgcca gggccgggtg gtcgtgcacc
     9961 cgcaggtcgc gggtgaacag caccaccgcc gtacggccgc tcacgtcagc gccgggccgg
    10021 gcaccacgac cggggtgccg gtacgggcga gcagcgcctt cgccgccacc gacagccgac
    10081 gccgctgggg caccacggcc cgctggacga acacgtcgta gtcctgggcg gcgacctcgt
    10141 cgaggatgcc gccgtagagg gcgtacgcgg tgcgcatgca cgcctgggag gcgggggcga
    10201 gcagggtgac gcccggcgcg gcggcggcgt agtgggcctg ggcgcgggtc acctcgtact
    10261 cgatcaggtc acggatccgg tcggtgctgc ggccggtggc ctgggcggcg cgcaggtcct
    10321 cgggggtgac gttgaacttg gccaggtcct cgtcgggcag gtaggtgcgg ccccggtcga
    10381 ggtcctcggc gacgtcccgg atgaagttgg tcaactggaa ggcgaatccg agctggcggg
    10441 ccggctcccg ggccgcgacc gggtcggagc tgccgaggat gggcagcatc atggtgccga
    10501 tgacggccgc cgagccctcc atgtagtcga gcaggtcgtc ataggtgggg tacgacagga
    10561 ccgtcaggtc catcgccatg ctgcgcagga acgacgcgaa gtcggtccgg tccaggtcga
    10621 acacggcgat ggtgtgcagc accgccggca gcagcgggtc gtcgaccggc tcgccgtgca
    10681 ggccggcgac gaagcgggag ccccaggcgt ccagccgggc ggcgcgttcg gcgggcggca
    10741 ggtcctcggt gcggtccacg atctcgtcgg cgtagcgggt gaagccgtac agggcgtgca
    10801 cgtgtcgccg tttccatgcg ggaagcagcc gggtggcgag atagtaggtg cgcccgtggt
    10861 gtctgtgcag ctcctggcag cgggcatagg cagcggtgag atcggtgtcc accgggcctc
    10921 ctctgattcg acgcagcaat cgacgcaact cgtaacccta gggtacgctc gcccccatgg
    10981 ccaacgacgc agttgcgggt aatgcgctcc gcgtcgcgcc ggcacagccg ggagcgacgg
    11041 acgatccggt ccacggcgta cttgtcgctt tcgcccgtga cctggtcaac gacgtcgacg
    11101 acacgttgtc ggcgttcctc acccgcgaag tcgacgcact gaccgagatc gacgcagcga
    11161 tgggcggctt cgccgcgacg gcacgcgagt ccgtgctggc cggcggcaag cgggtccgcc
    11221 cgaccttcgc ctactggggc tggcggggcg tggtgggcgg cgacgcgccg ctgcccaccg
    11281 tgctacccgc gctggccgcc ctggagctgc tgcacacctt cgccctggtg cacgacgacg
    11341 tgatggacgc ctcggacacc cgccgtggcc tgcccaccgt gcaccgggcc gccgccgccc
    11401 ggcacgtcac cgccggacac accggtgacc cgagccggtt cggtgagtcg gttgccgttc
    11461 tcatcggcga cctctgcctc gtctgggcgg accggctgct cgcccacgcc accgtgccgc
    11521 ccgcccggct gctggaggtg cggcgctgct acgaccagat gcgcatcgag accatcgccg
    11581 ggcagtacct cgacgtgctc ggcgagaacg acgcggcgaa ctggtcggtg gaccaggcgc
    11641 tgcgggtggc ccgctacaag acggccagct acaccgtcca gcgtccgctg ctcttcggcg
    11701 ccagcctggc cggcatcgcg cccgacgcgc cgctgatcgc cgcgtacacc cgctacgggc
    11761 tggcggtggg cgaggcgttc caactccgcg acgacctgct cggcgtctac ggcgacccgg
    11821 cggcgaccgg caagccggcc ggcgacgacc tgcgcaccgg caagccgacc gtgctgctga
    11881 tgctcgcccg tcagctcgcc accggtggcc agcggcgggc gttggagcgg gccggcaccg
    11941 ccgtcggcgt ccgcgaggtg gcccggctgg ccgacatcgt cgccgacacc ggcgcggtcg
    12001 gccgggtcga gcacatgatc tccgaccggg tcgccgacgc gctcgccgcg ctggggaccg
    12061 cgtcgatcga cgagacggcg cgcaccgcgc tgaccggtct cgccaccgcc gccaccacgc
    12121 ggcgggcatg atgggcaact tcgtgaagga ggtggtcgcg tgcgtaccgt gacgggacgt
    12181 acggaccggg tggtggtcgt cggcgcgggc ctgggcgggc tggcgtgcgc gctgcacctg
    12241 gccggcagcg gccgacaggt gaccgtgctg gaacgcgaac cggtgcccgg cggacgggcc
    12301 ggtcggctca gcgtcgacgg gtacgagttc gacaccggcc cgaccgtgct caccatgccc
    12361 gacctgatcg ccgaggcgct cggtgcggtc ggcgaggagc tgtccgactg gctcgacctg
    12421 accccgatcg accccgccta ccgggcctac tacccggacg gctccacgct ggacgtgatc
    12481 accgacacca cccggatggc ggccgagatc tcccgggtct gcggcccccg ggaggccgac
    12541 ggctacctgc ggttcgtcga ctacgcccgc aacctgtgga actgggagcg ggccgacttc
    12601 atcgaccgca acctggacgc cccgaccgac ctgctcaccg gcaacctgct gaaactgctc
    12661 gccagcgggg cgttccggcg gctccagaca aagatcaacc agttcttctc cgacccccgc
    12721 acccagcgga tcttctcctt ccaggcgatg tacgccgggc tctcgccgca cgacgcgctg
    12781 gccatctaca gcgtcatcgc gtacctcgac tcggtggccg gggtctactt cccgcgcggc
    12841 ggcatccacg cggtctcccg ggggatggcc ggcgcggccg agaagcacgg cgtgcagatc
    12901 cggtacgaca ccacggtcac ccgggtggag accgccaacg gccgggccac cggggtggtg
    12961 accgccgacg gcgagctggt cccggccgac gtggtggtgc tcaacccgga cctgccggtc
    13021 gcctaccgtg acctgctgcc cgggggccgg cagcgcaagc tgacctactc gccgtcctgc
    13081 gtggtcctgc acatcggatc gacgcagggg tatgggaaga tcgctcatca caacatccac
    13141 ttcgggcggg cctggaaggg caccttcgac gaggtgatcg ggcgcggtga gctgatgagc
    13201 gacccgtcgc tgctggtcac caacccgagc cggaccgacc cgtcggtcgc cccggacggg
    13261 cggcacacct actacgtgct ggccccggtg cccaacctcg accgggcccc gttcgactgg
    13321 cggggcgacc tgagccggcg ctacgccgac cagctcgtcg ccacgctgga ggagcgcggg
    13381 tacgtcgggt tcggcgccgg catcgaggtg ttgcgtacga tcacccccgc cgagtgggag
    13441 gagcagggaa tggctgccgg tacgccgttc gccgccgcgc acaccctctt ccagaccggg
    13501 ccgttccgcc cgtccaacct gcaccggagc ctgcccaacg tggtcttcac cggttccggc
    13561 acccagcccg gtgtgggcgt gccgatggtg ctgatctccg gcaagctcgc cgccaaccgc
    13621 atcaccggcg cggggcggtg accgcgtgaa gtcccgggag ggtcacctcg tcgagctggt
    13681 cgacgacacc ggccgggtgc tcggtgaggc caccgtcgcc gccgcccacc aggcacccgg
    13741 acggctgcac cgggccttct cggtgctgct ggtcgacccg gacggccggg tcctcctgca
    13801 acagcgggcc ccggtcaaga cccggttccc gctgcgctgg gccaactcgt gctgcgggca
    13861 cccgctgccg ggcgagtcgc tggcggaggc ggccaaccgc cggctcaccg aggagttggg
    13921 cgccgggccg gtgtcgctga ccgaggtcgg tgtctacctc tactacgccg aggacccgac
    13981 caccggtcgg gtcgagttcg agtacgacca cgtgctccgg gccgacgtgc cgaccgggct
    14041 caccctgctg ccggacccgg acgaggtgtc cgagctgcgc tgggccgatc cgaccagggc
    14101 gatggccgag atcgacaccg acccgcgcag ctacgcgccc tggctcggcg gagtgctgag
    14161 ccgcctgctc cgcccgaccc cgaccggtcc caccgctgac cccaccctcg ccactgccac
    14221 cgccggtccc accactcccc ccggcgccca cgccgccggg tccgccaccc cgtccggccg
    14281 ccgggtggac gacgtgtcgg agcggtcggg tggtcgatga gccgctgagc gcgggggccg
    14341 tggcacgccg gctgggtgtg gcggtcacca ccctgcgtac ctggcaccag cgctacggcc
    14401 tcggccccag ccagcacatt cccggtcacc accggcgcta cacgccggct gacctggccc
    14461 gcctggagat catgcggaaa ctcaccgccg agggggtcac cccggcggag gcggcccgct
    14521 gggcgaaaca gagtcccggt gtcgcggtgc ggctgccggc caggaccggc cgggacggcg
    14581 gcgggcagac catcccggtc ggccgggccg gaccggcggc ccggggactg gcccgcgccg
    14641 ccatgcggct ggacgcggcg gtgatcggcg acacgatctc gcacgcgctg gccaccgacg
    14701 gggtgatcgc cacctgggag gggctgctcc gcccggtgct ggccggcatc ggtgagcggt
    14761 acgtggcgac cgccggcctg atcgacgtgg aacacctgat gtcccggtgt gtctccgagg
    14821 cgttcgccgc cgtcgcccac tccggccggg ccgccgggcc ggcccgcatc ctgctctcct
    14881 gcgccgacga ggagcagcac accctgcccc tggaggcgct ggccgcggcg ctggccgagg
    14941 cgggggtggc ataccggatg ctcggtgccc gggtgccggt ggcggcactg gtcgaggcgg
    15001 tcaaccggac cgggccggcg gccgtggtgg tctggtcgca cacccgtctc accgccgatc
    15061 cggggcagct ctccgccctg ctcgcggtgc cccgccggcc gctgctggtg ctcgccgccg
    15121 ggccggggtg gcgggccgac acgctgcccg ccggggtggt ccggccggtc gatctggccg
    15181 aggcggtgtc actcgcgctg gccgtccggg attcgttgga ccagtcgacc ggggccgacc
    15241 gggcctgaca tatttcgctt tcgtgaacta ccgtcggggc cgtccgcgta cccccacccc
    15301 cccggagtga cgatgcgttc acgccccgtc ctggcggttg ccctgggtct gctcctgctg
    15361 gtcgccggtt gtggcgatca gccccggcac gtccggccgg ccgccgcgcc cgtcccgacg
    15421 acctccgcgc ccgagccgac ccgcaccccg gccgcgacac cgccgccgac cagcaagccg
    15481 aaaccccggc tgcggcccaa gccgaagacg ctccccgccg ggttgcggaa ggcgaccggg
    15541 gtacgcgcgg tggcgttgac cttcgacgac ggccccgacc cgacctggac gccgagggtg
    15601 ctcaaccagc tccgggcggc caaggtgaag gcgacgttct gcgtggtcgg cacccaggtc
    15661 cgcaagcacc cggagctggt ggcccggatc gtccgggaag ggcaccagct ctgcaaccac
    15721 agctggcacc acgacgtcga cctgggccgc cggccggtcg ccgagatccg ggccgacctg
    15781 gtccgcacca accaggccat caccaaggcc gtcccgggcg cgaaggtgcc gttctaccgt
    15841 cagcccggcg gccggtggac gccggaggtg gtggcggtgg ccaaggagct cggcatgcgt
    15901 gcgctgcact ggaccgtcga cccccaggac tgggcgaagc ccaccgccgg cgtcatcacc
    15961 ggacgggtcg agggtgccgc ccgccccggc gcggtggtgc tgatgcacga cggcgggggt
    16021 gaccggagcc gcacagtggg cgccgttccg cacgtcatcg gcgacctgaa gcgccgtttc
    16081 gggatcgcgc cacctcgctg agctgctgct ttgtccggcc gcgccccgcc gggcataccg
    16141 gtttggccga ccgccggggc atgacatatg cttctcatgc ctccggcggg gccggatggg
    16201 agcaagtccg cttgaagttg cgagtgtgca atgatggcgg ggccgccctc atcgtctagc
    16261 ggcccaggac gccgcccttt caaggcggta gcacgggttc gaatcccgtt gggggcacgg
    16321 tccggcctgg ccggaggcaa caccagcaag gtcctgtgga gcagttggag tgctcgccgc
    16381 cctgtcaagg cggaggtcgc gggttcaagt cccgtcagga ccgccagcgc cgacgccgcg
    16441 tgcaccattg cgcggcgttc tgcgtatcgg gacgcatcac cctgtcggcg gagaccccgc
    16501 cctccgggta acatgtcccg aggcaccagg ccaggtagct cagttggtac gagcgtccga
    16561 ctgaaaatcg gaaggtcggc ggttcgaccc cgcccctggc cacatagcct ttcgccgggc
    16621 tacagaagac ggtgacctgc ggaaacgcgg tcaccgtttt cgcgtatccg gctccccccg
    16681 ggaccgtttc accggagttc tcccgaccgg ccgggccgga cggtggttcc gtctccggtg
    16741 gcctgggtcc attgtccgga acgggccagt acgcgaggct gcagagcgcc tcatcagccg
    16801 gtatggtccg ggcctatggg acaggagaat gcgaatccgg aggacgtcca gcaggacgtc
    16861 gaccggtact cgctgcgctc cacgctcctc gtccccgcca ccgcggagca ggcgttcgcg
    16921 gtcttcaccg gctcgttggc cgactggtgg gtacgcgaat acacctggtc cgggccggcg
    16981 gcgcttgccg agctggggat ggagccccgg gccggcggca tgctctatga gatcggcccg
    17041 tacggcttcc ggggcgactg gggccgggtg ctcacctggg acccgccgcg gcggctcgtc
    17101 ttcacctggc agctcggccc cgaccggctc ccggtgcccg atccggcccg cgccagcgag
    17161 gtggaggtgc tgttcctgcc ggacgagtcg gggcacaccc gcatcgagct ggagcaccgg
    17221 catttcgacc ggcacggtga ggccgccgag ggctaccgcg aggcgttgac ggccggctgg
    17281 cacgagctgc tcggccgcta tctcgccacc ctcaccggca ccgccccggg cccgcactga
    17341 ccccaccggg cggtcggggg cgttcaccgc gtcgggagtc cgcggtgcgc ccgggtggtc
    17401 ggggcgtcca ccgcgtcggt gccaccgagg tccgcccggt ggccggctgc cgcccccgcg
    17461 ccgaacccgg agccggcgag ccggcggatg ggcgtggtcc gcagccgggg atagacctcg
    17521 gtgacccggc gggccacccg gtcggagcgg tcggccagca ccagcgcgac cgacgaggtg
    17581 tcccgctgcg ccaccgcgtc cgcctcggcg acccgcagcc ggtcggagat cacccgggcg
    17641 aagccggcca accaggaccg ccggaacgcc gccggatgct cgccgggcgg gaccacggtg
    17701 ccggcgagtc cgtgtgcggc ctgcaccagc agtgaggtga agagcaggtc gacccgctcc
    17761 aggtcactgg cgaagccgaa caggtgcagc gcgaatccgc tgccggccgg tcgtcgtacg
    17821 cagcggcagc gcagcgggtc ggccaccgcc gcgagcagcc cggccttgtc ccgggcgtac
    17881 ggggcgacga cgtcgaccac ccggtcgccg accgggtcgg tggtggggtc gcgggcggcc
    17941 agcagggcgc ggtcgacgcc gtaccgggcg atcaactcgg tggccttggc ggtgaaggcg
    18001 gccgcctcgg cgggggtgca ggcggcgtcc tctgcctggg ccaacagctt gcgcaccttg
    18061 ctgagcatcg cctcggacat gcgtcactgg taccacagaa ggttcatggg tctgtcacag
    18121 cgggatcaga gatcgacaga tatcatcgcc actcaccgca ccctgtccac gactcagggt
    18181 ccgcccctct ccctggaggc accaccatgg catcccggac cgctcgcctg gccgcactcg
    18241 ccgccaccct gcccctgctc tggcacggcg cacccgccca ggccgccccg gagaccaacc
    18301 tctccgcgtc ggccgccacc tgctacggcg gggcggtccg gtcctacttc caggccggcg
    18361 gatggggcgg ggacgccggc ccgtacaagg cgagcgcccg gtgcaaggac gtcaacgtca
    18421 agaacagcag cgcgttcggc accgaggcgt gcgtggtctt catcgacaag accaacagct
    18481 gcaactacct gacctacctg ccggcgaagt cggactggat caccgtcgcc accaacgtgc
    18541 gcgacggcgc gaacttcaag gtccgcttca ccaacctgcg ctacgagtac gagccgctgg
    18601 tggcgtacca cgcgtactga gccggccggc gcggcgtccg caccgggcgt cgcgccgtca
    18661 gccggcccgg ctgcgcaggg tggccacggt cgagccggcg agggtgagca ggcagtccgg
    18721 cagctgcccg tcggcgaccg ccgccccgaa cagcgcctcg ccggtgtcgg cgtcgtggtt
    18781 ggcgtacgcg ctgacgaagc gggccaccca gcgggtgtcg taccccgcgt cgtcgatgcc
    18841 cgggaagtcc agcgcgcagg cgcccggtgg cgggtcgccg accatggtgg cggccagggt
    18901 ccaggcgacc gtgtacgccc cggcgaggcc ggaccggtcc accaccgcgt cgaatgtgcc
    18961 gaccaccgcg gcgccgtctc cggacagcgc cgagtggagt acggcggtag cgtcggccag
    19021 cgtctgatcc ggtacgtcgg tcacctgcgg cacagtagga cgccaggtca agcgaacaga
    19081 gcgccgagat ggtgaccacc tgctgagacg acgtgacaca ccgtgaggtc tgctgtcggg
    19141 ccggcgacca gggcagcctc cctggtccca cggttgtcgt cggcacgcta tggtgcgcac
    19201 cggacctgcg ccggaggaag gacgaccatg ctcgttacac gcggcccgcg cccggccatc
    19261 ctggcggcct gcgcgtcgtt cctgctcgtg atcagcgcct gcgggacgac cgacaagccc
    19321 gaggaggcgg ccaccccgca ggtacgcctg tacggcaccg acggcaacat gctcaactcc
    19381 ttcgccgccg agctgaagga ccgggccgat ctcgtcgacg gcatgaaggg caccaccccg
    19441 ctcacgccgc tcaccgacga cttcaagcag cggctacgct ccgtcgaccc gaagttgacc
    19501 gactacctgt acgcggcgga gtcgtacgac gcggtcatga tcagtgcgct ggccgcccag
    19561 ctggccggca gcaccgatcc ggccgacatc gccaagcaga tcgtcggggt gaccaccaac
    19621 ggtcagcgct gcaccgacgc ggcgagctgc ctgcccctgg cccgggacgc ccaggacatc
    19681 gagtaccgcg gccagtcgct gacccgcgcg ggcttcaccg acatcgggga gccggccacc
    19741 gccagctacg cgaccctgca cttcgacaac cagaagatca acgacgcgaa gaccgagttc
    19801 gtcggcgccg gggacgagtc cggggtgagc accaaggccg cccccaagcc gaagaagcag
    19861 cggggcgggc gcaacgacag cagcgacggc tccccactga tcctcggcgg tctgctgccc
    19921 aagaccggcg acctggccct ggcgaaccca ccgctggcgg ccggcgtggc actggcgctc
    19981 aaggagatca acgccgccgg tggggtgctc ggcgatccgg tggtctggat cgacggcgac
    20041 gacggcacca acccggccgt cgccaaggcc accgtggcct cgcacgtcaa ggacaaggtc
    20101 cacgtcatca tcggggccgc cgcgtccggc atctccagcg cggtgctgcc ggacgtggtg
    20161 gcggcgggga agatcctctt ctccccgtcc aacaccgact ccgggttgag ccaggccgac
    20221 gacaagggcc tctacttccg gaccgccccg ccggacagcc tccagggtcg ggccctggcc
    20281 gacgtgatcc tgcgcgacgg cccgcacaag atcgtggtgg tggcccgcaa ggactcgtac
    20341 ggcgagggcc tccaggagac cgtccgggcc gagctggagc gggccggctt cggcaacgac
    20401 cgggtgaagc tgttcaccta cgacccgccg gccgacgcca aggccccgcc ggtcgacttc
    20461 ggcaacctgg ccggcgacat caagggctac cgcccggagg ccgtgctggt catcggcttc
    20521 ggtgagtccg ccgggctgat caaggcgctg gccgacgcgg gcgtaccgat ccgccactga
    20581 cgccgacaca tcggtggggc agcaccggct ccggtgctgc cccaccgccg gttcagcggg
    20641 gtcggcggcg ttccaggaaa tcggtcatcc ggcggtgctt ctcctcgtcc tcgaagagca
    20701 ccgcctgact gaccaggtcc agctgcgggt gggcggcggc cggggcgtcc accgcgagtt
    20761 tggtcagccg cagcgccagc gccgaaccct cggccatctc gtcgagcagc ccgtgcgcgg
    20821 tgggcagcaa ctccgccggc tccgccacca cccggttcac cagaccgatc cgcagcgcct
    20881 cgtcggcgtc gacccgccgg ccggtgaaga gcagttcctt ggcccgcccc tcgccgatca
    20941 gcgccggcaa ccggtgggtc gccccggcgc cggccaggat gcccaaccgc acctccggct
    21001 gaccgaagac cgcccgggaa gtgcacaccc gcaggtcgca ggcgtacgcc agctccgccc
    21061 cgccgcccag cgcggggccg tccacggcgg ccacgctcgg catcggcagg gcccggagcc
    21121 gggcgaaggc cgccgagttg atcgcggcga gggcgtccag ccgaccccgc tcccgcagct
    21181 gaccgatgtc ggccccaccg gcgaagaggc cgtccgcgcc gccggtgagc agcagcagcc
    21241 ggggccgggc ctccagtgcc gcacacacgt cgtgcagcgc gccgatcagg tcggcgtcga
    21301 tggcgttgcg cttctccggc cggtccagcg tcaccaccac ccggtcgggc agctcctcca
    21361 cccgaagtcc gctcattgcc gccgaccctc cttccacgcg tagaagccct ggccggactt
    21421 cttgccgagc ttgccggcgg cgaccatctc caccagcagc ggcggcggcg cgaaccggtc
    21481 accgtaggcg gcctgaaggg tacgggcgat gtccagccgc acgtccagcc cgaccaggtc
    21541 ggtcagctcc aacgggccga ccgggtgccg gtagccgagc accatcgcct tgtccacgtc
    21601 ggcggggtcg gccaccccgt cggccaccat ccggatcgct tccaggccga gggtcacccc
    21661 gagccgggag gtggcgaagc cgggcaggtc gcgtaccacg acggggtcct tgcccaaccg
    21721 gccggcgagg gcgacggccg ccgcggtggt ctccggtgcg gtggccgcgc cgaccacgac
    21781 ctccagcagg gccatcgccc agaccgggtt gaagaagtgc agcccgagga aggactccgg
    21841 ccgggccagg ccctcggcca gctcgccgat ggggatgctg gaggtgttgc tgcccagcag
    21901 cgccgggtgc agccgctccg cctcggcgag caccgaccgc ttcagctccg gtcgttccgg
    21961 caccgcctcg acgatcacct ccggtgccgg ggcgacctcg gcgagcgcgc cacgcagggt
    22021 gatccgggcc cgctgcgcgg cggcctcgtc ggcaccgagc ttcccccgct gcaccgcccg
    22081 ggcgcacagc tcgtcgaggc ggacggcggc agcctcggcc cgaccccggt c
//
