LOCUS       NZ_FMCU01000005        18004 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000005
VERSION     NZ_FMCU01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 440844
            Orig. end                         :: 458848
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18004
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="5"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..18004
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18004
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:16388](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16388
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            671..847
                     /locus_tag="GA0070216_RS34525"
                     /old_locus_tag="GA0070216_105410"
     CDS             671..847
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS34525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_105410"
                     /product="hypothetical protein"
                     /protein_id="WP_176738960.1"
                     /transl_table=11
                     /translation="MTKAPWLLVIILFALLVGTVTAWIWSRSGATILETFKAGGSACAA
                     AFGVGITGFYFLS"
     gene            complement(1116..3095)
                     /locus_tag="GA0070216_RS13955"
                     /old_locus_tag="GA0070216_105411"
     CDS             complement(1116..3095)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023946.4"
                     /locus_tag="GA0070216_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105411"
                     /product="DUF3732 domain-containing protein"
                     /protein_id="WP_245722495.1"
                     /transl_table=11
                     /translation="MAIVLYSRRGQKRVVGFKPGALNIVTGESQTGKSALVAITDYCLG
                     RDEIMVPIGREFATVAWYGALWQLDGGRAFVGRPAPAPGRASSTVAMLEFGSDLDVPDF
                     EDLAPNTDSTSLRQQLSRRIGIEEHLAEPPPGSLRRAFEVGMGQAALLCLQDQDEIDSS
                     QALFHRASDRAIADSIRDAFPYFLGAVPQDQALKHAQLRDARRALSRLEAQVRAAELRS
                     ANLDAELRALLNEASSVGLVGESTLPDDRAAMILLLQQARVRPVAEPAPLPDTVQQDRR
                     LGLERRSRELHRLLKKVMSDRALLLDQQDGQSGYRNAIELQVGRLQSLGLLDLLPPDDE
                     AGEHSASEQASICPACNSSLIDGRDRTNVDLGRSLRFLRSQLGDLRAAPPARRGAIEGL
                     EAEVSRLRDEISAVDGALEGLLNSARINEDVPVSAVDFTRGRIDASLARIEALDEREVI
                     ILRSRLLDAERRVLALEAELDDDQDREELTSRLLAISRDMTSYARYLGLEHSSENVRLE
                     LSRLTVVADTEEGPAPLFRIGSGANWVGYHLVTHLALHKYFVRQNRPLPRFLILDQPSQ
                     AYYPSAARAGAQTRDADPEAVKRLFKLIFDVVESLEGRLQVIVIDHADEPEEWFGRSIV
                     HNWRDGEKLIPVGWLEAVADESSS"
     misc_feature    complement(1548..1550)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2109..2111)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3106..3121)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            complement(3110..3622)
                     /locus_tag="GA0070216_RS13960"
     CDS             complement(3110..3622)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039805.3"
                     /locus_tag="GA0070216_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="three component ABC system middle component"
                     /protein_id="WP_218108200.1"
                     /transl_table=11
                     /translation="MVTHSEVNALASALRPSIPAVMLNPALFAALAAAAAEEYQRRSGH
                     YMPWYMSFLVAPLVLHRSTREVLPRDTRTHMANWVNSHAVIIAGFPARARELVGPVQEG
                     IRFGLRHEVFEIDQDGGLRGALSESARPERASGDLSALIRAAGLVGRWLTKLDQPATAF
                     ALLGVTP"
     misc_feature    complement(3419..3421)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3634..4839)
                     /locus_tag="GA0070216_RS33795"
                     /old_locus_tag="GA0070216_105412"
     CDS             complement(3634..4839)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042658.2"
                     /locus_tag="GA0070216_RS33795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105412"
                     /product="ABC-three component system protein"
                     /protein_id="WP_141723090.1"
                     /transl_table=11
                     /translation="MSSGEHNASGSMVGYLYQADWCLLELIRRGPDRPDLAISLEMHDD
                     VAWDEGGTPRELLQTKHHLNSNAGLGDKDKDLWKTVLVWINAGSPGDSHGPRLGLVSTS
                     VAADDSAAGLLRPDERRKTDEALRRLDKAAAESTNEVTKKAREKYLALTPAERGAFVER
                     IFVLDRAPRIGDVESELRKALWNALPTDHEDMFMGLVWKWWHGVSLDMLQGRRSGITAA
                     AARAEIAGIRNRFGDDDLPTTVELADVDTKGVLLAHENSPFVHQLRWVRCNSVNLRKAI
                     IDYYRAVEQTVAWVDDDLIGLHELKRFEEELRDEWERHFADMVEDLGESASDDEKIAVG
                     KNLLRQLRDSTSVSVRPKYNDAFFARGKRHELADRGSVGWHPDFQALMENLMISTARQS
                     QA"
     misc_feature    complement(4039..4041)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4213..4215)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4979..5143)
                     /locus_tag="GA0070216_RS34530"
     CDS             complement(4979..5143)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS34530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176738961.1"
                     /transl_table=11
                     /translation="MKIGLVRSGVSMAWIVDDELWKLIEPVLPSSFGTLNIGRRRRGSL
                     LPKQHPACA"
     misc_feature    5727..5741
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.81"
                     /tool="antismash"
     gene            6225..7559
                     /locus_tag="GA0070216_RS13965"
                     /old_locus_tag="GA0070216_105413"
     CDS             6225..7559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020609517.1"
                     /locus_tag="GA0070216_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105413"
                     /product="transcriptional regulator"
                     /protein_id="WP_091245150.1"
                     /transl_table=11
                     /translation="MSRQEVAEAVNNYLWDTYGTRTSMDANHVGKLERGEHRWPKPTTR
                     EAFRAVLKAPRDADLGFYITRGQCHSDPVAHQIPPGEMLTAGDDHAGESLIGGEITDTG
                     DMNRRELLRLLSLTGALLAAPVPASQLDWARIESSGDGNRRLDPAALDEYEGLNAQLWA
                     AFGAAESKAAVSPLVNRQLTTLTANLRRSHTTPVHRRLCGVTADLLQLAGEVAFDANAY
                     SEAAHCYTLAATAAREAAAYDLWACAMIRHAFISVFERDFRHAAPMLDVAASLAQNGDS
                     ALSTRHWAHTVRAQALAGLGDLSGCRQALDQAEEVNHLPGQVHNGGWLRFDGSRLAEER
                     GACYVELRRPDLAEPVLSGALSQSLSTRRRGTVLTDLALVGVQRSDVHQIVLYGSAALD
                     TARQSGSGVVGSKLNQLHHRLRPFLADTHVRHLNRQISALVRAGN"
     misc_feature    7209..7211
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7561..7956
                     /locus_tag="GA0070216_RS13970"
                     /old_locus_tag="GA0070216_105414"
     CDS             7561..7956
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583799.1"
                     /locus_tag="GA0070216_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105414"
                     /product="hypothetical protein"
                     /protein_id="WP_091245152.1"
                     /transl_table=11
                     /translation="MTRGRTSVQVEEPGRVFREAWIAGVRKHYPGEPKPGYVTPWQDTP
                     EWERESAAAVYELVRQFIEAADGATAKLTREQKGRFVALSWIAQIFKHFPNPKASYVAD
                     WSDMPEWQRETDSDIFEHIEQTLVSTR"
     gene            complement(8149..8358)
                     /locus_tag="GA0070216_RS13975"
                     /old_locus_tag="GA0070216_105415"
     CDS             complement(8149..8358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012180837.1"
                     /locus_tag="GA0070216_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105415"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_091245154.1"
                     /transl_table=11
                     /translation="MTMHPEKFTNWRKSSRSGGGDNCIEVAFALDGTVGMRDSKDRRGP
                     VLGFTRGEWTAFTDGIRDGDLDAH"
     gene            complement(8355..9230)
                     /locus_tag="GA0070216_RS13980"
                     /old_locus_tag="GA0070216_105416"
     CDS             complement(8355..9230)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012180838.1"
                     /locus_tag="GA0070216_RS13980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105416"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_141723091.1"
                     /transl_table=11
                     /translation="MISPYVRRRRLATELVRLREEHGYSAERLCKETKIAKQKLSRLEN
                     ARVRPDQDEIMRVLDHFRVGEKRWEEIMAIARESQENGWWENFRVEMGPRQALYADLEA
                     GAEHIAEYHITLLPGLLQIPAYTEVRAVADRAAYPRRFTVERALEARAARQRVLDRPGG
                     PTYEVIIDELAIRRHAAPPEVVRAQLDHLINVGHEKQKTTIRVLRLTARIAGNAVPRSS
                     YFSYRYPDPSDPVVVAVDTITSDLVLTDPDEVANYASLYERLRSAALSPADSLDFLASV
                     AEELPDYTRR"
     gene            9754..9888
                     /locus_tag="GA0070216_RS13985"
                     /old_locus_tag="GA0070216_105417"
     CDS             9754..9888
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016815038.1"
                     /locus_tag="GA0070216_RS13985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105417"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_091245159.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.1e-14, bitscore:
                     48.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLLAVSNDPFELDVQIVTDGPVAAALLADTDDGCDTVKGSDC"
     gene            10001..13030
                     /locus_tag="GA0070216_RS13990"
                     /old_locus_tag="GA0070216_105418"
     CDS             10001..13030
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020609516.1"
                     /locus_tag="GA0070216_RS13990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105418"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_091245162.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-180,
                     bitscore: 596.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2e-19,
                     bitscore: 64.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1e-24, bitscore:
                     82.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRSVDAATIRIAAHSWPDGPAPWPDRSDTSGVADWLQATWRKVG
                     LAEAVWAASPEFAARVEAVLATGSATPDRGWRMALALARYLVRAQRRATPFGLFSGVAT
                     LRFDTVAAVVPAGQSAIRVRPDASWLASLIARLEVEPDVRRRLPVQANNLALVNGPRIV
                     VARRPHASARTESTSVRSTAAVRLAVSLARSPLPWAELLDAVAAAFPGFPRASADTMVA
                     GLVDHGVLISALRPPSTCTDPIRHVLDTLDAAFDGDPEGQRALRVELRSLHGRLGGTRP
                     ASATYLRGLADRMRSVAPANQPLAVDLQLADQVALPEQVAAEIAASVEVLRRLTPDPAG
                     RPEWRVYRARFVDRYGMTAVVPLARLVDPLVGLGVPEHFGALGNAPAAPLSGRDERLLA
                     MAQQAVIDGVREVVLDDAAVEWLAGAGRVIGPVSPHVDVSAEVRAVSLEALTQGRFTVA
                     LTGMGRSAMATSGRFLDGLPYADRELMCREFARLPVAVDGAMPVQLSFPPRKLHSQNVL
                     SSRQVLPWLVSLAEHRPVAENVIGLDDLGVTAGRDRLVLVSMSRRRVVEPTVAHAAAVH
                     TMPLLGRFLLELPRATDARLKPFDWGAASCLPFRPALRYGRVLLAAARWRVDPAALPGA
                     DASDGEWLTAWEALRTRLRLPAWVQVGNGDQRLRLRLDQSMDRALLRAHLDASAGPVTV
                     VDAASPKDFGWLSGRAHEIVVPVASTVAPAAAPAAVTARGAWPPPAPPEPIMPGASGLL
                     SASVAVDPSTMELVLARELPALFADWPEPPLWWFVRMRRPTPQLRLRLHTDDYGDAAVR
                     VGRWVGGLRQQRLAGDWSLDTYQPESGRYGCGTALAAAEKLFAADSTAALAQLVALPES
                     GINRQALTALSMVDLTASMLGSRTDGCEWLVARPEQTGQAPVQRDVLRQAVTLDPSELP
                     EPIQHAWRERSRAAARYVAELSAVAGPLTPASVLASLMHLHVVRALGPDEDAEQLTYRL
                     ARHVALAAVRRRVRAKGASR"
     aSDomain        10448..10711
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GA0070216_RS13990_Lanthipeptide_LanB_
                     RRE.1"
                     /evalue="1.30E-20"
                     /identifier="RREFam001.1"
                     /label="GA0070216_RS13990"
                     /locus_tag="GA0070216_RS13990"
                     /protein_end="237"
                     /protein_start="149"
                     /score="64.9"
                     /tool="antismash"
                     /translation="QANNLALVNGPRIVVARRPHASARTESTSVRSTAAVRLAVSLARS
                     PLPWAELLDAVAAAFPGFPRASADTMVAGLVDHGVLISALRPP"
     gene            13027..14289
                     /locus_tag="GA0070216_RS13995"
                     /old_locus_tag="GA0070216_105419"
     CDS             13027..14289
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018794744.1"
                     /locus_tag="GA0070216_RS13995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105419"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_091245166.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-42, bitscore:
                     140.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEAPLRTPLLRAAEAMAACITDTLTEPPPPDFAADDYGPRSSRW
                     YAQSLSRGAAGVALLHGVRAQTGHGGWEPVHAWLRRATADTLNSGSGAGLWFGAPAVTH
                     ALTTAMPHARPAALDTLDHALDDQVERRLAAATARLAARARPSLSEFDLVRGLTGLGAH
                     LLCRASHGPLLRRVLAYLVQLTEPVHTDDEAGRLAPGWWSADPTDREGPEQGGHANVGM
                     AHRITGPLALLALAMRQNIRVPRHAEAIRRICTWLDRWQQTSPAGPWWPEKITVAELRA
                     GKPSMSGPARPSWCYGTPGVARAQQLAGIALDDAARQEAAEEALTRCLADPLQLSRIVD
                     PSLCHGWAGLAATAWYAAADARTADLQKQLPQVVRLLIQHATDTTPARSGLITGAAGIA
                     LTLHTIATGTDVRWATSLLIN"
     gene            14304..16388
                     /gene="fxlM"
                     /locus_tag="GA0070216_RS14000"
                     /old_locus_tag="GA0070216_105420"
     CDS             14304..16388
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020609514.1"
                     /locus_tag="GA0070216_RS14000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105420"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_091245171.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-23, bitscore:
                     77.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 1e-40, bitscore: 134.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLDSEPDTEPPGVAPASRWRQINLTLSDWQSAEDFAATRLAPEL
                     AAAEDHRTITAFWFIRKSETWRLRLLPGDRLAQVYALLASITDDDRIRGVTEPVYRPEA
                     YAFGGDQAMTIAHTLFHADSRHILGHLATTGGTHRRELGVLLATRLLRAAGLEFSEQGD
                     VWRLLASRRHQPNAPAPSPRLIAAVQRLQTAADDTAASPLVITPQWPRAQEQAGADLGF
                     LDRHGALTRDLREVLTHHLLFLFNRLGISAADTWLLATAAVTVTFHHPFDTPSGYQPAA
                     KIGSRVNAVNTSPTAPGTSSAATLRDQLASTLGQRGHIRSGAVAHAFRTVPREQFLPGV
                     DLETVYTRRQIVTKRDPSGAALSSASSPSLVADMLEQLAPQPGHRVLEIGAATGINAAL
                     LAELTSPGGTVVTIELDQDLADGARAGLDRAGYDTVKVICGDGALGDPEHAPYDRIIVT
                     AGAWDISAAWWEQLADHGRIVVPLRVHESGLTRCFAFDRTDPHQLVSTTTPLVCGFVPM
                     RGTAEHTDHHVRLDTDVVLKLDATDQPDRAALASALSHSRLERWTGIQVSDADPIGHLD
                     LWLLVHATRPFGRLGVGDTARTSGLVTPAYRWAGAAIYHGGTIAYLAFQDAGNGHHEIG
                     AIAHGPDATTLATELTNLLDQWDEAHRPNQPTVTAHRAGSRPADHGDISRADTILTISF
                     "
     gene            16512..16691
                     /locus_tag="GA0070216_RS14005"
                     /old_locus_tag="GA0070216_105421"
     CDS             16512..16691
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS14005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_105421"
                     /product="hypothetical protein"
                     /protein_id="WP_091245173.1"
                     /transl_table=11
                     /translation="MTPSLAATIAARFPLVARKRPPAKPLDARVDRLVRLAETAHCESD
                     PDKASMVFNGAAWA"
     gene            16762..17064
                     /locus_tag="GA0070216_RS14010"
                     /old_locus_tag="GA0070216_105422"
     CDS             16762..17064
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="GA0070216_RS14010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105422"
                     /product="transposase"
                     /protein_id="WP_176738962.1"
                     /transl_table=11
                     /translation="MGKKRPRPRRSFTAQFKAEIVELCQRGDRTIRQVSDDFDLTETAV
                     RDWVKQAELDTGTRSDGLSSDEKAELAQLRRENRRLREDVDILKRATAFFAKETR"
     gene            17061..17957
                     /locus_tag="GA0070216_RS14015"
                     /old_locus_tag="GA0070216_105423"
     CDS             17061..17957
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="GA0070216_RS14015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_105423"
                     /product="IS3 family transposase"
                     /protein_id="WP_091245182.1"
                     /transl_table=11
                     /translation="MNVYPFIEAEKAGKHNVTRACELMKVSRSAYYQHATGQQSQRDLT
                     DQALTAKIIEVHAMSKGTYGAPRVHAELTDAGLRHGRKRIARLMRDVGVRGKSPRRWQT
                     TTITDPAAADRADLIGRDFTTDPARIDTRWCGDITYINTWQGWLYLATVIDLASRRVVG
                     WAVADHLKTDLIDAALNDAIVRRRPPSGLIFHSDRGCQYTSAQHARLAATHSIRLSNSR
                     RGQCWDNAVAESFFATVKTELLHRQPWPTHTAARQATFEYIEGWYNTRRRHSSLGYLSP
                     AAYEATRHTIQPVHQAA"
ORIGIN
        1 ccaaggacga cccgatccgg atcctggccc acgaactgga cttctggctc ccacccgtga
       61 cccaggtact cgaggactac ctgcgtgagt tcccggtggt gaacaatgac atcgtcccgg
      121 gcccggtgcc actggaggac ggctcggtgc tgtccggggc aacgaccgct aacccgcgga
      181 caggcgggga cctttggtgt ggtgaggagg aggcggccga ggcggtacgg cgcaccgtgg
      241 gggcagccga tgccaccgga cggctacgcg gcatcctcga cgcagttcga tcgcaccgct
      301 gcgaggacga cttctcaccc ctctggagcg gtgcccggga ggacttcgag cgcaagctct
      361 accacaagcg cgccaagctt caggtccggt ttgtcgagct gtctgacacg atccccgtgc
      421 acggcccgga aacggaggtc gtcgaccaac tcctgatcgg gaacttcctt gcactcttgg
      481 acacgcgtga ccgcaccatc gtcgtgctgc ttcgtagcgg cttcaccaag ctgaccgaag
      541 ttgccgagac catgggatac cggacccata gtgccgtctc aaagcggatg gatcacatcc
      601 tcaagcgggc ggcccgcttc gctcagacct tggactcgtg atcgctatgg ggaatccagg
      661 cggtgacccg atgacgaagg caccctggct gctggtgatc attttgttcg cgctcttggt
      721 cggcaccgtg accgcctgga tttggtccag gtccggggcg acaattctgg agactttcaa
      781 agccggcggc agcgcctgcg ccgctgcttt cggcgtcggt atcaccggct tttactttct
      841 ttcctaacat gctacgtagc cgaagttcaa caggcttgac ggcctcctcg acaggcgcag
      901 gtgcatctct atccgggggc acgtcacaga actgcaaaca cacaacgcgg ccagtcgatc
      961 attggtcgtg gaagccaggt tcgtgttgga gtagacgatc aaggatgccc cggccgagcg
     1021 gccggggcat cggacgttgg ctcgatgcac gggcgctgaa cgcaccgtat cgcggcaagt
     1081 ccggatgcgt cctgcgccgc aggaaaggat catttctacg aggaactttc atccgcgacc
     1141 gcctcaagcc atcccacggg aatcagcttt tcaccgtcac gccagttgtg cacaatggaa
     1201 cgcccaaacc actcttcagg ttcgtcggca tggtctatga caatcacctg aagtctaccc
     1261 tcaagagatt ccaccacatc aaagatcaac ttaaacagtc gctttacggc ttctggatcc
     1321 gcgtcccgtg tttgcgctcc agcccgtgcg gccgacgggt aataagcttg actcggttga
     1381 tcgagaatca aaaatctcgg cagcggacgg ttctgacgca cgaagtactt atgcaaagca
     1441 agatgcgtaa caaggtggta gccgacccag tttgccccac tgccgatcct aaacagcggc
     1501 gcgggaccct cctcagtatc cgcgacgacc gtgagccggg acagctctaa gcgaacgttc
     1561 tcacttgagt gctccagacc tagataccta gcgtaggaag tcatgtctcg actgatagcc
     1621 aacaaccttg acgttagctc ttcacggtct tgatcatcat ccagttcagc ttcaagtgcc
     1681 agcaccctac gctcagcgtc aagcaatctg gaacggagga tgatcacctc tcgctcatcg
     1741 agtgcttcga tcctagccag cgaagcatca atacgccctc gcgtaaagtc gacggcactg
     1801 accggaacat cttcgttgat tctggcggag tttagaagtc cttccagcgc gccgtcgaca
     1861 gcggagatct cgtccctcag acgactaacc tccgcttcca agccttcaat agcgccccgc
     1921 cgtgcaggcg gagcagctct tagatcacca agctgactcc gcaggaaacg aaggctgcgt
     1981 ccgagatcca cattcgtacg atctcggcca tctatcaagg aactgttgca cgcagggcaa
     2041 atgcttgcct gctccgatgc agagtgttca ccagcctcgt catcaggcgg caaaaggtcg
     2101 aggagaccta aactctgcag gcgccccacc tgcaactcta tggcattacg atagccgctt
     2161 tgcccatctt gctggtcgag aaggagggct cgatcagaca tcaccttctt cagcagtcgg
     2221 tgcaattcac ggctacgccg ttcgagtccc aaacgacgat cctgttgcac cgtatcaggc
     2281 aatggcgcag gctcggcaac aggacgaacg cgcgcctgct ggagcaagag gatcatcgcg
     2341 gcgcggtcgt caggcagcgt ggactcaccc accaagccca cgcttgaagc ctcattgagt
     2401 agtgcccgga gctcagcatc gaggttcgcg cttctgagtt cagctgcccg gacctgagct
     2461 tccagccggc tcaatgcgcg gcgcgcgtcc ctcagctgag catgcttgag cgcctgatcc
     2521 tgaggaaccg cccctaggaa gtagggaaaa gcgtcgcgaa tcgagtccgc gatcgccctg
     2581 tcactggctc gatgaaagag cgcttgcgag ctgtcaatct catcttgatc ttgaaggcaa
     2641 agcaaagctg cttgccccat gccgacttcg aaagctcgac gaagggagcc cggcggaggc
     2701 tccgcaagat gctcctcgat tccgatcctc cggctgagct gctgccggag agaggtcgaa
     2761 tccgtgttgg gcgcaagatc ctcaaagtcg ggaacatcga gatcgcttcc gaactcaagc
     2821 atggcgaccg ttgaggaagc ccttccagga gcaggagccg ggcggccgac gaaagctctc
     2881 cccccgtcga gttgccacag cgccccgtac caagccaccg tcgcgaactc gcggccgatg
     2941 ggaaccatga tctcgtcgcg ccccaggcag tagtccgtga tcgctactag agcgctctta
     3001 ccagtctgcg actcccctgt aacgatgttg agagcacccg gcttgaagcc gacgaccctc
     3061 ttctgacccc gtctgctgta gagaacaatc gccatgagct gcacggtgac tagggtgtca
     3121 cacccaacag cgcaaaggct gtagccggct ggtccaattt ggtcagccac ctgccgacga
     3181 gtccagcggc acggatcaac gcggacaagt caccgctagc gcgctccggt cgtgcgctct
     3241 ccgacagcgc tcctctgagc ccaccatctt gatcaatctc gaagacctca tgccgcaggc
     3301 cgaaccggat gccctcctgc accgggccaa ccagctcgcg cgccctggcc gggaaaccag
     3361 cgatgatcac ggcatgactg ttcacccagt tggccatgtg ggttcgggta tctcgcggta
     3421 atacctcccg agtgctccgg tgaagcacca aaggggcaac caagaaggac atgtaccaag
     3481 gcatgtagtg cccagaccga cgctggtact cctctgcggc cgccgccgca agtgcggcga
     3541 atagggcagg atttagcatt actgcgggta tagagggtcg cagagccgac gccagcgcat
     3601 taacctccga atgcgtcacc attataccta gcgctaagcc tgcgattgac gagccgtcga
     3661 gatcattagg ttttccatca aagcctggaa gtcaggatgc catccaacac tgccgcggtc
     3721 agctagttca tgccttttgc cacgcgcgaa gaaagcatca ttgtacttcg ggcgaacgct
     3781 cacggacgtc gagtctctca actgacggag caggttcttg cccactgcaa tcttttcgtc
     3841 atcgctagca ctttcgccga ggtcctcaac catgtctgcg aagtggcgct cccactcgtc
     3901 gcgcaattcc tcctcgaatc gtttgagttc atgcagtcca attaggtcgt cgtccaccca
     3961 ggcaacggtt tgctcaacag ctcgataata gtcgattatt gctttacgga gattgaccga
     4021 gttgcaccga acccagcgta attggtgcac gaacggacta ttttcgtgcg cgagaaggac
     4081 gccctttgtg tcaacatctg ccaactccac cgtagttggc agatcatcat ctccgaagcg
     4141 gttgcgaatg ccggcaattt cggccctcgc ggccgccgca gtgatccccg agcgcctccc
     4201 ctgaagcatg tctaaggaaa ctccgtgcca ccatttccat accaacccca tgaacatgtc
     4261 ctcatggtca gtaggtaggg cgttccacag cgccttacga agctccgact caacatcgcc
     4321 gattcgagga gccctgtcaa gaacgaaaat tctttccacg aatgcgccgc gttctgcagg
     4381 ggtcagagct aggtactttt cccgagcttt tttggtgacc tcgttggtcg attccgccgc
     4441 agccttatcg agtctgcgca gcgcttcgtc agttttccta cgctcatcag ggcgaaggag
     4501 gccagcagcg ctatcatctg ccgcaacact tgtcgacacc aggccgagcc ttggcccgtg
     4561 tgaatcccca gggctaccgg cattgatcca aacaagaacc gtcttccaaa ggtctttgtc
     4621 tttatcgccc aggcccgcat tggagttcag gtgatgcttg gtctgtagaa gctcgcgagg
     4681 cgtcccgcct tcgtcccaag caacgtcgtc gtgcatttcg aggctgattg cgagatccgg
     4741 tcgatcaggg ccacgcctga tcaactcaag caggcaccaa tccgcctggt agaggtagcc
     4801 caccatgctt ccagaggcgt tgtgctcccc ggacgacatg tcacctagtc tgcaccctga
     4861 cgaccggaca ggtccagaac ctgatgcccg cagcatgtcg tcgcgatctt ggtccggtca
     4921 ggtttggtgg gcgtcacctg cgggacggcc gtcacgcagc ccagctaaca gcaagacgtc
     4981 aggcgcatgc tggatgttgc ttcggaagca gcgatccgcg ccgtcgccgg ccaatgttga
     5041 gggttccaaa gctgctcggc agcaccggct cgatcagctt ccacaactcg tcatcgacga
     5101 tccacgccat gctcacgccc gaccgaacga gaccgatctt cacccccgtc ctgatcagcg
     5161 tcgattcacc agatctcgtt aggagcttac caaggcgagc gttagtttct tggctgtcga
     5221 tgcggttagg gtgttatgcc ttgatgtagg cgaggtgtgg ggcagcgaag aacccacgca
     5281 cgatctaggg catcttctgt aggcgtctta gcgcgccgat agtgaggcgt ttcatgtccg
     5341 cctggctcat ggggcggcgc gtttgatccg gtcgtgcttc acgttcttcc atacctactc
     5401 gtcggggttg attccgggga gtacccgggc aggaagaaca gcttgagttg ccgttggtgg
     5461 actccaccta actggaccgc acggacacgt tcctcatgaa tcgatctacg gacattcctc
     5521 gccattcggt cattcgtcca cgcctaacat ggacagtcca ggaactttcg aactccttgg
     5581 taagtctggc ccaacttgaa ggtggtcaac tggcgtccag ctattccggc aataccgcgt
     5641 cggtgagtag caggatgcct cagtttgctg ttcgcccgga ggtcgcccac aggggcaggg
     5701 tataagggtg gctgcgtcac ctctggaatt tccagaactt cttcttcacc tccatgcccc
     5761 gctgcgataa cctgcatatc aaacatgacc gcgcgtcgaa ctccatcgct caccgtgacg
     5821 ctcgctcggc ggcagattag tagacccgtt tggttgcggc agctcctgtt ggcgctgccg
     5881 tgctcgtcag gggcgagcag gccacccgga cggttgcggt cagcctgacg ttccgttgat
     5941 agttcgtctt gtgatcagga agtcacactg gcatgctggc gtggcattcc ggcaaaccgg
     6001 accgtcgggt cgcctcgttc ggccgaatgg aggccgaggt ccggcggacc aaagatgagg
     6061 gatgagggtg gcagcgatct tgcagagccg cccgagaggg ctaccagcga gtttcgacgg
     6121 gcggtgaggg gttggcaccg aggtcgggtg cgccagatgg ccccaacacc ctgctcagtg
     6181 acgcccgccg ccggcttctg tccccgagcg gttcaggccg acggatgtct aggcaggagg
     6241 tcgccgaggc ggtcaacaac tacctgtggg acacctacgg cacgagaacc agcatggacg
     6301 ccaaccacgt cgggaagctt gagcgaggag agcaccgctg gcccaagccc acgacccggg
     6361 aggcatttcg tgcggtgcta aaggcaccac gggacgctga cctgggcttc tacatcaccc
     6421 gtggccaatg ccattctgat cccgttgcgc accagatacc ccctggcgag atgctcaccg
     6481 ctggtgatga tcacgctggc gagtcgctga tcggcgggga gatcacggac actggcgata
     6541 tgaaccgccg cgagttgcta cgcctgctga gcctgacagg tgcgctgttg gccgcgcccg
     6601 tcccggccag ccagctcgac tgggcgcgca tcgagtcatc cggtgacggg aacaggcgac
     6661 tagacccagc ggccctcgac gagtacgagg ggctgaacgc ccagctgtgg gcggccttcg
     6721 gcgcggccga gtccaaggca gcagtatcac cgctggtcaa ccgtcagctg acgacgctca
     6781 cggcgaacct acgccgctcc cacacgacac ccgtgcaccg caggctctgc ggggtcaccg
     6841 ccgacctgct ccagctcgct ggcgaggtcg ccttcgacgc gaacgcgtac agcgaggccg
     6901 cgcactgcta caccctggca gcgaccgccg cccgagaagc cgctgcctac gacctctggg
     6961 cgtgcgcgat gatccgtcac gccttcatca gcgtcttcga gcgcgacttc cggcacgccg
     7021 caccgatgct ggacgttgcc gccagcctgg ctcagaacgg ggacagcgcg ctgtcgaccc
     7081 ggcactgggc acacactgtg cgggcacagg ctctcgcggg cctcggcgac ctcagcggat
     7141 gccggcaggc gctcgaccaa gccgaagagg tcaaccacct gcccggccag gtgcacaacg
     7201 gcggatggtt acgcttcgac ggctcccggc tcgccgagga acgcggagcc tgctacgtcg
     7261 agttgaggcg cccagacctg gccgagccgg tgctgtccgg tgctctgtcg caaagcctct
     7321 ccacacgacg acgcggaacc gtcctgacag acctcgcctt ggtcggagtt caacggagcg
     7381 acgtacacca gatcgtgctc tacggcagcg ccgccctcga tactgcccgc caaagcggct
     7441 cgggcgtggt cggctccaaa cttaaccaac ttcaccaccg cttgcggccg ttccttgccg
     7501 acactcacgt gcggcatctc aaccgccaga tcagcgccct ggtaagggca gggaactgac
     7561 atgaccagag ggaggaccag cgtgcaggtc gaagaaccgg ggcgcgtgtt ccgcgaggca
     7621 tggatcgcgg gagtccgcaa gcactacccc ggcgaaccga aaccgggcta cgtcacgccc
     7681 tggcaagata cgcccgaatg ggaacgggag agtgccgctg ccgtgtatga gctggtccgc
     7741 cagttcatcg aggcagccga cggcgcgacg gcgaagctga cccgtgaaca aaaaggacgc
     7801 ttcgttgccc tgtcctggat cgcgcagata ttcaagcact tcccgaaccc gaaggcttcc
     7861 tacgtggccg actggtcaga catgccggag tggcagcgag agacggactc ggacatcttc
     7921 gaacacatcg agcagacgct cgtctcaacg cgctgagcgg aagacaagtc gacaggaacg
     7981 cgcacttctc actcccatgc ccgccgtccg ggtgcttctg agtcggcgcg aggtcggcgg
     8041 gcggggcgca ccgaccagca tgatcagtac atgcaagcgg tgacactcat gtcggccgag
     8101 gtcagcgcgg cgcgcccggc ttcccgggcg cgccgacgag acagcagttc agtgtgcgtc
     8161 aaggtcaccg tcgcggatgc cgtcagtgaa cgccgtccac tcacctcggg tgaaccccag
     8221 cactggtcct ctccggtcct tcgagtcccg cattcccacg gtgccgtcga gcgcgaaggc
     8281 gacctcgatg cagttgtcgc caccgccgga gcggctggac ttccgccagt tggtgaactt
     8341 ctcggggtgc atggtcatct cctggtgtag tcgggcagtt cctccgccac gctggcgagg
     8401 aagtcgaggc tgtcggcggg gctgagggcc gcggaacgca ggcgctcgta cagggaggcg
     8461 tagttggcaa cctcgtccgg gtcggtgagg acgaggtcgc tggtgatggt gtcgaccgcg
     8521 acgaccaccg gatcgctcgg gtcggggtat cggtagctga agtacgacga ccggggtacc
     8581 gcgttgccag cgattcgcgc ggtcagccgc agtacccgga tcgtggtctt ctgcttctcg
     8641 tgaccgacgt tgatcaagtg gtcgagctgc gcgcggacga cctccggcgg tgcggcgtgc
     8701 cgacggatcg cgagctcatc gatgatcact tcgtaggtgg gtccgccggg tctgtccagg
     8761 acccgttgcc gggcagctcg ggcttccagt gctcgctcca ccgtgaatct ccgggggtag
     8821 gcagcacgat ctgccaccgc gcggacctcg gtgtacgccg ggatctgcaa caaacccggc
     8881 agcagggtga tgtggtactc ggcgatgtgc tccgcaccgg cttccaggtc cgcgtagagg
     8941 gcctggcgtg gtcccatctc gacgcggaaa ttctcccacc atccgttctc ctgggactca
     9001 cgagcgatgg ccatgatctc ttcccaccgc ttttcgccaa cccgaaagtg gtcgaggact
     9061 cgcatgatct cgtcttgatc tggtcggact ctcgcgtttt ccaaacggct cagcttttgc
     9121 ttggcgattt ttgtctcttt gcagagcctc tcagcggagt agccgtgttc ctcccgtagt
     9181 cgcacgagtt cggtagcgag ccggcgacga cggacatatg gactgatcac cgatacctcc
     9241 ggcgagagac gcgaatagcc cggtgatcca tcctgcctgg accccggcga cgagagcgta
     9301 acgcctgttt taccgatcat cgctagcgcc gaccatgctt tccgcaaaga aaccccagtt
     9361 caagcgcacg acgaccggta agtctccccc tagctttccc catttgtcgg tgttcccggg
     9421 gttacgcaag aaccgcgatc gtggaagcac cacaagcaat gtgtctacgg cttgtaatgg
     9481 gggcgcgcgg cgacaggttc gcggcggagt cccgacgatc cgaggtgcgg gaggaacggc
     9541 atggacgcca cgagcgcaac gctgatagcc gttcggtata cctgaggccc ctgcccgctg
     9601 tcgctgccgg ggagggcgtg gcggcgggca ggccgaacgt cgcgagttct catggacgcc
     9661 gttttagaaa ggcggatcga tccgcctgcc aacgtgccgg tagctgcggg ggctacctgc
     9721 ccacccaaca tcccagtccc attggaggct tccatgaaca gcctgctcgc cgtcagcaac
     9781 gacccgttcg agctcgacgt gcagatcgtc acggacggtc cggtcgccgc cgcgctgctg
     9841 gccgacacgg acgacggctg cgacaccgtg aagggcagcg actgctgatc gaacaccctc
     9901 gctggttccg gcaggcgatc ccccgatgcc tgccggaacc agcaccccac atccagccgt
     9961 gcccccggag gagcgcctcg tgacggaagg aggacgattc atgtttcggt cggtcgatgc
    10021 cgcgacgatc cgcattgccg ctcactcatg gcccgacggc ccggctcctt ggccggaccg
    10081 gagcgacacc tccggtgtcg cggactggtt gcaagcaacg tggcggaagg tcggcttggc
    10141 cgaggctgtc tgggccgcca gccctgagtt cgctgctcgc gtagaagcgg tcctcgccac
    10201 aggaagcgcg actccagacc gagggtggcg gatggcgttg gcgttggcgc ggtacttggt
    10261 ccgtgcgcag cggcgtgcga cgcccttcgg gttgttctcg ggggtggcga ctctgcggtt
    10321 cgacacggtg gctgcggtgg tgccggcggg gcagtcggcg attcgggtac ggccggacgc
    10381 gagttggctc gcgtccctga ttgcgcgcct tgaagttgag cccgacgtgc gccgccgtct
    10441 gcctgtgcag gcgaacaacc tggcgctggt gaacgggcct cggatagtcg tggcgcgccg
    10501 gccgcacgcc tctgcacgta cggagtcgac ctcggtcagg agcaccgcag cggtacggct
    10561 ggcggtgtcg ctcgcccgtt ccccgttgcc gtgggctgag ctgctcgacg cggtcgctgc
    10621 tgcgtttccc ggcttcccac gcgcgtccgc tgacacgatg gttgccggcc tggtggacca
    10681 cggcgtgttg atctccgctc tccgaccacc atcgacgtgc acggacccga tcaggcatgt
    10741 cctggacacc ctcgatgcgg cgttcgacgg tgatccggag gggcagcgag cccttcgggt
    10801 cgagctgcgc tcgctgcatg gtcgtctcgg tggtactagg ccagcgagcg cgacgtacct
    10861 tcgtgggctc gccgaccgca tgcgcagcgt cgcaccggcc aaccagccgc tcgcggtgga
    10921 tcttcagctc gcggatcagg tcgccctgcc ggagcaggtc gccgccgaga tcgccgcatc
    10981 ggtggaggtg ctgcgacggc tgacgccaga tccggcgggg cggcccgagt ggcgtgtgta
    11041 ccgtgcccgg ttcgtcgacc gctacgggat gacggctgtg gtgccgctcg ctcgactggt
    11101 agatccgctc gtcgggttgg gcgtcccaga acacttcggc gctttgggca acgcgcctgc
    11161 ggcaccactg tccggccgtg acgagcgtct gctcgcgatg gctcagcagg cggtgatcga
    11221 tggtgttcgt gaggtggttc tcgatgacgc ggccgtcgaa tggctcgccg gcgctggccg
    11281 agtcatcggg cctgttagcc ctcacgtcga cgtctcggca gaggtacgcg cggtctcgct
    11341 ggaggcgctg acacagggac ggttcactgt cgcgctgacc ggcatgggcc gctcggcgat
    11401 ggcgacgagc gggcgtttcc tcgacgggct gccctacgcc gaccgggagt tgatgtgccg
    11461 ggagttcgcc cgccttccag tcgcggtgga cggggccatg ccagtgcaac tgagcttccc
    11521 gccgcgcaag ctacacagcc aaaacgtgct cagctcccgg caggtacttc cgtggctggt
    11581 cagcctggct gagcaccggc ccgtggctga gaacgtgatt ggcctcgacg acctcggtgt
    11641 gaccgccggc cgggatcggc tggtgttggt gtcgatgtcg cggcggcggg tggtggagcc
    11701 gacggtggcg cacgctgccg ccgtacacac gatgccgctg ctcggccggt tcctcctgga
    11761 gctgccgcga gccacggatg cccggctgaa accgttcgac tggggtgcgg cttcctgctt
    11821 gccgtttcga cccgcgctga ggtacgggcg cgtcctcttg gcggcggccc ggtggcgggt
    11881 cgatccggcg gccctgcccg gtgcggacgc cagcgatggc gaatggttga cggcctggga
    11941 ggcgctgcgg acgaggctgc ggctgccggc atgggtgcag gtcggcaacg gtgaccagcg
    12001 gcttcggctc cgcctcgatc agtccatgga tcgtgccctg ctgcgtgccc acctggacgc
    12061 cagcgccgga ccggtcaccg tagtggacgc ggcgagtccg aaggacttcg gttggctctc
    12121 cggccgcgcc cacgagatcg tcgtgccagt cgcctcgacg gttgcgcccg ctgccgcgcc
    12181 ggctgcggtt accgcgcgag gcgcatggcc gccacccgct ccccccgagc cgatcatgcc
    12241 gggtgccagt ggcctgctgt ccgcttcggt ggccgtcgac ccttcgacga tggagctggt
    12301 cttggcccga gagctgcccg cgctgttcgc cgactggccc gagccaccgc tgtggtggtt
    12361 cgtgcgcatg cgacgcccca ccccgcagct tcgactacga ctgcacaccg atgactacgg
    12421 cgacgcggcg gtacgggtcg ggcgatgggt cggcgggctc cgacagcagc gccttgccgg
    12481 cgattggagc ctggacacct accagcccga gtccggtcgg tacggctgcg gcaccgcgct
    12541 ggcagcggcc gagaaactct tcgccgccga ctccaccgca gccctggcac agctggtagc
    12601 gctgcccgag tctgggatca atcggcaggc gctgaccgcc ctgagcatgg tcgacctgac
    12661 cgcctcgatg ctcggcagcc gcaccgacgg atgcgagtgg ctggtggcgc gccccgagca
    12721 gaccgggcag gcaccggtcc agcgagacgt gctgcgccaa gcggtcaccc tcgacccgag
    12781 cgaacttccc gagcccatcc agcatgcatg gcgggagcgc tccagggccg ccgcccggta
    12841 cgtagccgaa ctgtccgccg tcgccggccc gctcacccca gcctcggtgc tcgcgtcgct
    12901 gatgcacctg cacgtcgttc gcgctctcgg tcccgacgaa gacgccgaac agctcaccta
    12961 ccggttggct cgccatgtcg cgctggcggc ggtgcgtcgc cgggttcgcg ccaaaggagc
    13021 atcccgatga ccgaagcacc gctgaggaca ccattgctcc gggcggctga ggcgatggcc
    13081 gcgtgcatca ccgacaccct gaccgagccg ccgcccccgg atttcgcagc ggacgactac
    13141 gggccacgca gttcccgctg gtacgcccag tcgctgtccc ggggtgccgc cggggtggca
    13201 ctcctgcacg gggtgcgagc gcagacagga cacggtgggt gggaaccggt tcatgcctgg
    13261 ctgcgacgcg cgaccgctga cacgctgaac agcggcagcg gagccggact ctggttcggc
    13321 gcacccgctg tcacccacgc gctgaccacg gccatgcccc acgcccgccc agcagccctg
    13381 gacacgcttg atcatgccct cgatgaccag gtggaacgcc gcctggccgc tgctacggca
    13441 cgcctcgcgg cgcgtgcccg gccctcgctg tcggagttcg acctcgtacg cgggctgacc
    13501 ggcctgggag cccacctgct gtgccgcgcc tcgcacggac ctctgctccg gcgggtgctg
    13561 gcgtacctgg tccaactcac cgagccggtg cacaccgacg atgaggcggg ccgactcgcg
    13621 ccgggttggt ggagcgcaga ccccaccgac cgcgaaggtc cggagcaggg cgggcacgcc
    13681 aacgtcggca tggcgcaccg catcaccggc cctctggctc tcctggccct ggccatgcgg
    13741 cagaacatcc gggtgccgag gcacgcggag gcgatccgcc ggatctgcac gtggctcgac
    13801 cgctggcagc agacaagccc tgcgggaccg tggtggccgg agaagatcac cgtcgcggag
    13861 ttgcgcgccg gaaaaccctc catgagcgga ccggcgcggc cgtcctggtg ctacggcacc
    13921 cctggagtcg cccgcgccca acagttggcc ggcatcgctc tcgacgacgc cgcccgccaa
    13981 gaggcggcag aagaggccct gacccgctgc ctggccgacc ccctccaact cagccggatc
    14041 gtcgatccgt cgctgtgcca cggctgggca gggctcgccg ctacggcctg gtacgccgcc
    14101 gccgacgccc gcaccgccga cctccagaaa cagcttcccc aagtcgtgcg cctgctgatc
    14161 caacacgcca cggacaccac cccggcacga tccggcttga tcacaggcgc cgccggaata
    14221 gccctcaccc tgcacaccat cgcgaccggc accgacgtcc gctgggccac cagcctgctg
    14281 atcaactaga cgaggagagc gtcgtggatc tcgactccga acccgacacc gagccaccag
    14341 gcgtggcgcc ggcgagccga tggcgccaga tcaacctgac cctctcggac tggcagagcg
    14401 ctgaggattt cgccgcaacc cggctcgccc ctgagctcgc cgctgcggaa gaccaccgga
    14461 cgatcaccgc cttctggttc atccgcaaga gcgagacgtg gcggttgcgg ctactgcccg
    14521 gcgaccggct cgcccaggtc tacgccctcc tcgcctccat caccgacgac gaccgcatcc
    14581 gcggtgtcac cgagcccgtc taccgccccg aggcgtacgc cttcggcggt gaccaggcca
    14641 tgacgatcgc ccacaccctc ttccacgcgg acagccgcca catcctcggc catctcgcca
    14701 ccaccggcgg cacccaccgg cgtgaactcg gcgtcctgct cgccactcgc ctcctacgcg
    14761 ccgccggact ggagttctcc gagcagggcg acgtctggcg acttctcgcc tcgcgccggc
    14821 accagccaaa cgcccccgcg ccgagcccac ggctcatcgc ggcggtgcag cgcctacaaa
    14881 ccgcggccga cgacacggcc gcaagccctc tggtcatcac cccgcaatgg ccgagagccc
    14941 aggagcaggc gggcgcggac ctcggcttcc tcgaccgaca cggcgcgctg actcgcgacc
    15001 tacgcgaggt gctgacccac caccttttgt tcctgttcaa ccggctcggc atctccgccg
    15061 ctgacacctg gctactcgcg acggcggccg tgaccgtcac cttccaccac cccttcgaca
    15121 ccccatccgg ctatcaaccc gccgccaaga tcggaagtag ggtcaacgca gtgaacactt
    15181 cccccaccgc accgggaacg tcgagtgccg cgacgctgcg cgaccagctc gccagcacgc
    15241 tcggacagcg cggccacatc cgatccggcg ccgtcgcgca cgcattccgt acggtgcccc
    15301 gcgagcagtt cctccccggt gtcgacctgg aaaccgtcta cacccgccgc cagatcgtca
    15361 ccaaacgaga ccccagcggt gccgcgttgt cgtccgcgtc gagccccagt ctcgtcgcgg
    15421 acatgctcga acaactcgcc ccgcaacccg gccaccgcgt cctggagatc ggcgcggcca
    15481 ccggcatcaa cgccgccctg ctcgccgagc tgaccagccc cggcggcacg gtcgtcacca
    15541 tcgaactcga ccaggacctc gccgacggcg cccgcgccgg cctcgaccgc gccggctacg
    15601 acaccgtgaa ggtgatctgc ggcgacggag ccctcggcga ccccgagcac gcgccctacg
    15661 accggatcat cgtcaccgcc ggagcctggg acatctccgc tgcctggtgg gaacaactcg
    15721 ccgaccacgg ccgcatcgtc gtacccctac gcgtgcacga gagcggcctg acccgatgct
    15781 tcgccttcga ccgcaccgac ccccaccagc tcgtcagcac cacgacgcca ctggtctgcg
    15841 gattcgttcc catgcgcggc accgccgagc acaccgacca ccacgtacgc ctcgacaccg
    15901 acgtggtcct caaactcgac gccaccgacc agcccgaccg cgccgcgctc gccagcgccc
    15961 tcagtcactc ccggctcgaa cgctggaccg gcatccaggt cagcgacgcc gacccgatcg
    16021 gccacctcga cctgtggctc ctcgttcacg ccaccaggcc gttcggtcgc ctcggcgtcg
    16081 gtgataccgc ccgcaccagt ggactggtca cccccgccta ccggtgggcc ggtgccgcca
    16141 tctaccacgg cggcaccatc gcctacctcg ccttccagga cgcgggcaac ggtcaccacg
    16201 aaatcggcgc aatcgcacac ggcccggacg ccaccacgct cgccaccgag ctgaccaacc
    16261 tgctcgacca atgggacgag gcccaccgcc ccaaccagcc caccgtcacc gcgcaccgcg
    16321 caggatcccg gcccgccgac catggcgaca tcagccgagc cgacaccatc ctcacgatct
    16381 ccttctgacc gcagccaggc cggggcggtg ccctgtcccg ccccggtgga cgagcgcagc
    16441 tgagccgtca cgtacgacct gaacgcacct cgttgcccac atgcggccct tccgcagcgg
    16501 atgaggacac catgactccg tctcttgccg ccaccatcgc ggcccgcttc cctctcgtcg
    16561 cccgcaaacg accgcccgcc aaaccactgg acgctcgggt agaccggctc gtcaggctcg
    16621 ccgagaccgc acactgcgag agcgacccgg acaaggcgtc catggtgttc aacggggcgg
    16681 cctgggcctg acccgttttg acggacatcc gagatcagga gcccggtggg ctccgggagg
    16741 atgtccagca tcatggagag catgggtaag aagcggcccc ggcctcgccg gtcgttcacg
    16801 gcgcagttca aggccgagat cgttgagctg tgtcagcgtg gggaccgcac gatcaggcag
    16861 gtcagcgacg atttcgactt gaccgagacc gcggtgcgtg actgggtcaa gcaagccgaa
    16921 ctcgacaccg gtacccgctc cgacgggctg agcagcgacg agaaggccga actcgcccaa
    16981 ctgcggcggg aaaaccgccg gttgcgcgag gacgtcgata tcttgaagcg ggcgacggct
    17041 ttcttcgcga aggagacccg gtgaacgtgt acccgttcat cgaggcggag aaggccggca
    17101 agcacaacgt cacacgcgcg tgcgagctga tgaaggtctc ccgatccgcc tactaccagc
    17161 acgccaccgg tcagcagtcg cagcgagacc tgaccgacca ggcgctgacc gcgaagatca
    17221 tcgaggtgca cgcgatgtcg aagggcacct acggagcccc ccgggtgcac gccgaactga
    17281 ccgacgccgg gctgcggcac ggacgtaaac gcatcgcccg gctgatgcgc gacgtcggcg
    17341 tgcgcggcaa gagcccgcgc cggtggcaga cgaccaccat caccgacccc gcggcagccg
    17401 atcgtgcgga cctgatcggt cgggacttca ccaccgaccc cgcccgcatc gacacccgct
    17461 ggtgcggaga catcacctac atcaacacgt ggcagggctg gctgtatctg gccactgtca
    17521 tcgacctggc atcccgtcgc gtcgtgggct gggccgtcgc cgatcacctc aaaaccgacc
    17581 tgatcgatgc cgccctgaac gacgcgatcg tgcggcgccg cccaccgtct gggctgatct
    17641 tccactccga ccgcggctgc cagtacacca gcgcccaaca cgcccgcctc gccgccaccc
    17701 acagcatccg cctgtccaac agccgtcgcg ggcaatgctg ggacaacgcg gtagccgagt
    17761 ccttcttcgc tacggtcaag accgaactgc tgcaccggca gccgtggccc acacacaccg
    17821 ccgcccgcca ggccacattc gagtacatcg aaggctggta caacacccgt cgccggcact
    17881 cctcgctggg ctacctcagc ccagccgcct acgaagccac ccgccacacc attcaaccgg
    17941 tacaccaggc cgcctagata agatcaccac atcgaccccg tccgtcgaaa cgggtcaagc
    18001 ccag
//
