LOCUS       NZ_FMCU01000005        21140 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Micromonospora matsumotoense strain DSM 44100, whole genome shotgun
            sequence.
ACCESSION   NZ_FMCU01000005
VERSION     NZ_FMCU01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora matsumotoense
  ORGANISM  Micromonospora matsumotoense
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091525.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 03:45:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,745
            CDSs (total)                      :: 6,674
            Genes (coding)                    :: 6,498
            CDSs (with protein)               :: 6,498
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 35 of 176
            Pseudo Genes (incomplete)         :: 151 of 176
            Pseudo Genes (internal stop)      :: 7 of 176
            Pseudo Genes (multiple problems)  :: 16 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:03:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 25405
            Orig. end                         :: 46545
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMCU01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21140
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="2"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21140
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21140
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11140](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11140
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(221..234)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.37"
                     /tool="antismash"
     misc_feature    complement(223..241)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.57"
                     /tool="antismash"
     gene            complement(238..1089)
                     /locus_tag="GA0070216_RS12075"
                     /old_locus_tag="GA0070216_10530"
     CDS             complement(238..1089)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016818.4"
                     /locus_tag="GA0070216_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10530"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_091244096.1"
                     /transl_table=11
                     /translation="MSAFRNSPNVLFEAAVTATRRLSPGFVRITLGDERLRELAPHHLD
                     QRIKIMLPVAGDYPTELRAGLPEQEWRREWRAIPNPERPRLRSYTAYRTRPAAGELDLD
                     FYLHQPHGPASGWAAAARPGDRLLLSGPHVGAGHPGYGVQWEPGPATRVLIAADETAYP
                     AVRGILPSLGPGVRATVLLEAGTAADAATLDDVTAGHPVEVRLRGGAPGGTVLTAMVGD
                     WLAGHGLAAAAAEANFYAWTATESSRIAEVRRLFTEAGVDPEQVHTQGYWHDRPARDEI
                     DD"
     gene            1265..1825
                     /locus_tag="GA0070216_RS12080"
                     /old_locus_tag="GA0070216_10531"
     CDS             1265..1825
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077892.1"
                     /locus_tag="GA0070216_RS12080"
                     /note="This protein belongs to a clade of uncharacterized
                     proteins related to peroxidases such as the
                     alkylhydroperoxidase AhpD; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GA0070216_10531"
                     /product="peroxidase-related enzyme"
                     /protein_id="WP_091244099.1"
                     /transl_table=11
                     /translation="MPHITLNTSEPGIRGLFRFRPETALPLNALVEALLCGPGTLTRGE
                     RELIAAYVSGLNECRYCYSAHAAYAAAQLPEGMTLVEQVHDDVDSAPVSAKMRALLDVA
                     GAVQRGGREVTEDLVTAARAEGATDVEIHDTVLIAAAFCMFNRYVDGLATVLPDDPDFY
                     TDRAQRIAAHGYLGVLQQEVIRE"
     gene            complement(1860..3242)
                     /locus_tag="GA0070216_RS12085"
                     /old_locus_tag="GA0070216_10532"
     CDS             complement(1860..3242)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="GA0070216_RS12085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10532"
                     /product="FHA domain-containing serine/threonine-protein
                     kinase"
                     /protein_id="WP_218108191.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-34, bitscore:
                     114.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTDDPGVGRPAGAVPVTPPVTVTVRAGSTVDTYVFHRRTTVVVG
                     RAADCGIRVDDGQRRVSRRHCQLDIDPPNVRVRDLGSRHGTHLNGRPVDGERHLSAGDE
                     VRIGPATLRVTLPDDGTREAAAGPEDTGATPAGTTPTTPDTGTPGPDRGRALPVLVSAA
                     ADGAPGLDDFTDHRVLREIGRGGHSVVYLARHEPSGRLVALKTLLADRAVDPAARDAFR
                     REIACTRGLRHRNVVALHSGGAADDAFFFTSEYCPGGSVAEFVARRGGRLTADEAVPIT
                     LDALDALAYAHRAELAVVLADGRTEIAHGLVHRDVTPQNLLLATGPDGEVITKVADFGL
                     AKAFEKAGLSGHTGTGAIGGSIAFQARAQLIDYKYARPEVDLWAVTACLYWMLTGATPR
                     DFPVGVDPVAVVLRTRPVPVRQRLGTVPPRLAGVIDQMLVDQPRVTATTATELADALRQ
                     AR"
     gene            complement(3257..3931)
                     /locus_tag="GA0070216_RS12090"
                     /old_locus_tag="GA0070216_10533"
     CDS             complement(3257..3931)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013733336.1"
                     /locus_tag="GA0070216_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10533"
                     /product="SAVMC3_10250 family protein"
                     /protein_id="WP_091245204.1"
                     /transl_table=11
                     /translation="MSFRYYLYVSDAKVDMLLSQIDPGYQRRRAAEFSVNLTVVGVKRS
                     TENPGTDRVARLERVARYLDEHADVGSVEEPGQFFRGLLPMRWGIVPTTDEQSLVYFGG
                     RTEDTIVGLGGSPFHVIGAAPPEPTLRGFGGSSTMPALLAGLVDDGAEPVPGTPDGGDD
                     AAEVAALASVHQAGTRLRGPTQNVEFLAKRLLSGPSPYPELDGRPGMTVLLGSPLYVAL
                     VD"
     gene            4026..7601
                     /locus_tag="GA0070216_RS12095"
                     /old_locus_tag="GA0070216_10534"
     CDS             4026..7601
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="GA0070216_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10534"
                     /product="protein kinase"
                     /protein_id="WP_091244101.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-29, bitscore: 97.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPWRPGELILDLYEVRDQPLAGGMGLVYRVRHRGWDTDLAVKVPR
                     PEQLTTEAHRARFESEAGTWVGLGLHPHVVSCAYVRRVDGLPCVFAEWVAGGSLDQVVR
                     AGRLHEGPGGPDGGFLARALDLAVQSAWGIDHAHQQGLIHQDVKPANIMVGLDGAWTAK
                     VTDFGLAGARAAVDGVAGTAVEASLGASFGGMTPAYCSPEQAEAAAGARVTLTRATDVW
                     SWGLCVWEMFAGRRPCRYGQAAREAFADYLAAGETWPAAQPMPPGIVDLLRRCFDVDPT
                     TRPHHLADLATAVAGVYADTVGVPYPRVPPSAAGLLAGSLSNQALSLLDLDRPEDSEHL
                     WRNAIDIDPHHPAAVYNWALYRWRRGRITDEQVLAELRTAREIAGENWQADHLLGFVHA
                     ERGDDEAARPLLAASSTNPDVAEVAGALARRGTAPGPQRLPGHRGQVTAVAVDESGRVA
                     VTGGKDGSLRIWSLTENRAVRELGTDGAGAPVTTLAIDPAGRTALVAREGGRTERWNLA
                     RVGCVTVPLGQRAAVTALALTTSGAAAIGYDNGRIEVWDTTDGRLRRTLEHPPSTYQRL
                     DPATGRILPEIQESPAEVTVLGLSEDGTVAVSAAPRDGSVVVWEVDTGRWLHRLVKSAD
                     MRMTGVDEVALGGSGRYALLIGHQTRVAHLWETRPHRVRGPVPNNLNRYSTVVLSGDGE
                     RAVSVGVGSPDQPVRIWETDSGRCLRTVATRIDGLRPEMAGLLSLTCAATSGDGALVVL
                     GDEYGGLHVHRLPRPDLRAPWSYERPLAARAVLAAEAQVRQRVVRAESLAGEGRPAAAA
                     VELRAARDMVGFERHPQLRELWERLGRTAGERTAPLGVWQRYELRGGEFTFVPGLAPAL
                     SVDGELAVTGGADGLLRVWELRTGRQRHTFAERVGKAHTVVLSADAQLALSADWAGTAH
                     LWDLAAGRRQAELHGDHGAVRAVAMDGTGRYVIVGDADGNLCLWSLYRFHLSRTMVAHR
                     GPVGSVQLSDDGRYAASVGAEDRTCRLWRTGTGSPVLTIPVEFGSVPLRFTPDSRQLLI
                     NSPGELTAWDVQTGRQRYALPSRGDAMALSRDGRVGLVRAYDESYGRVVSVWETATGRV
                     LCELASEAKVFDVSPDGRHAVTADVDRTLGIWDVRTGRRVHTCDGHPEPVSSVAFTADG
                     RSMVSMDSRPAIRRWELDWDYDFTG"
     gene            complement(7591..8307)
                     /locus_tag="GA0070216_RS12100"
                     /old_locus_tag="GA0070216_10535"
     CDS             complement(7591..8307)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS12100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_10535"
                     /product="hypothetical protein"
                     /protein_id="WP_091244103.1"
                     /transl_table=11
                     /translation="MAPASAPSALIDAVVRVMRDLAVHPLSLEIDGDGARVLTTMHAHA
                     LRTRSRGPYRQDDLPPEALAMIDWLSLRLSVDPQRVDVTIEGGGPWPRLLLELPAKRVT
                     VRFVVPEDAPPGYQPESNNITLSGDVNIALEFLAGSLRALGGRLRGEPPVTLTLSYPDD
                     PHYERHIAGVPQEFRDLIPPVVADLAVDRSRFSRKQRAAHDDALRAAAYTDQPMEPVTG
                     GGLSTRLGSARLRVSP"
     gene            complement(8562..8975)
                     /locus_tag="GA0070216_RS12105"
                     /old_locus_tag="GA0070216_10536"
     CDS             complement(8562..8975)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461862.1"
                     /locus_tag="GA0070216_RS12105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10536"
                     /product="DUF6069 family protein"
                     /protein_id="WP_091244106.1"
                     /transl_table=11
                     /translation="MTTAANPPHATRSAIGALILTGVIATAAASVATVAVAAAGHAAGI
                     SLGVGDDTIPLSGFGLLTAAFSLVGVLLAVLLARFARRPRRTFVLVTVVLTALSLVPDL
                     LIDAGAATKALLILTHLVAAAIVVPALARRLAA"
     misc_feature    complement(9113..9127)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(9121..9131)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            9131..9403
                     /locus_tag="GA0070216_RS12110"
                     /old_locus_tag="GA0070216_10537"
     CDS             9131..9403
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS12110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070216_10537"
                     /product="hypothetical protein"
                     /protein_id="WP_141723063.1"
                     /transl_table=11
                     /translation="MGEQMISRRLRALSAAVAAATVALSIATPAMAAPATGPVLDITSI
                     AFDRPQVDVTEDYAAVSLTWTTTDRAAGAGTSRSTARPTVLPTSA"
     gene            9415..9927
                     /locus_tag="GA0070216_RS33730"
     CDS             9415..9927
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070216_RS33730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_141723064.1"
                     /transl_table=11
                     /translation="MPDEKAPVVFSARLPKATRTSQETADAWGLGFDVTIEVDEFAPIS
                     STSATNYDSTGASRGGMYGSRHDLTARTTRPLWAGPSGTVRARTAVPVRPEGFPWVRGT
                     ALPQCSTVRPTPPGAGLTALAATRRVETGDGTPRRSSTPCDVSCTRLWVIVRGDLPVSI
                     LLCHCKL"
     misc_feature    9907..9909
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9943..9955)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            10001..11140
                     /locus_tag="GA0070216_RS12115"
                     /old_locus_tag="GA0070216_10538"
     CDS             10001..11140
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442373.1"
                     /locus_tag="GA0070216_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10538"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_091244112.1"
                     /sec_met_domain="indole_PTase (E-value: 5.1e-94, bitscore:
                     309.9, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEVSLSDRLSDQLRRLCEVSGISAAEPLELLESLLGPAGPQPLS
                     APPGWPSNVADDHTPVEFSIAFSATEPPTVRILGETLGTPPARLTNMLATQRFLDRQAH
                     RAGLSTSRLDSVRDLFATYHPQGTFALWCSLVFRSGRRPEFKVYLNPELRGIDRAPALV
                     SEALHRLGLGRSYRAMLDRSIRPGELGHRDRLTFFALDLHDGAQARVKLYLTHHDASVR
                     DVVRAAGVVHDVDATRLAEFAALAGGGRTRFAGLPLVGSYTLVEGVDRPVGYSLYVPIR
                     GYVEDDEEAYDRVVAVLDHCGFDHTVLDRALAAVARRPLRDGVGLIPHLSLRMGAPRPG
                     VTVYLSAEAYQVSPPVRHPWTVDGAALAAPTGRAGAGHP"
     misc_feature    complement(10021..10041)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            11160..12566
                     /locus_tag="GA0070216_RS12120"
                     /old_locus_tag="GA0070216_10539"
     CDS             11160..12566
                     /NRPS_PKS="Domain: Beta_elim_lyase (49-427). E-value:
                     4.4e-69. Score: 224.8. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS12120_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442374.1"
                     /locus_tag="GA0070216_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10539"
                     /product="tryptophanase"
                     /protein_id="WP_245722457.1"
                     /transl_table=11
                     /translation="MSVDLHQMLPPYRIKVVEPIPFLSPQERRAALAEAGYNPFHLRAD
                     QITIDLLSDSGTGATSAAQEAAAALGDESYAGARSWFRFRDEVHDLTGYPHILPVHQGR
                     AGERVLFTGLLKPGQLCLSNTHFDTTHANVKLAGAEPRDLPCPAAFDLDSPDPFKGNID
                     LDALTRTLTGPERDRVGLVLMTITNNGLGAQPVSMANLTAVRDLCRRHEVPFFLDAARF
                     AENAWLVGQREPGYQDWTPRQIATHAFGLADGCVVSLKKDGLSAIGGLIGLRDDDLHAR
                     CEANLIATEGFSTYGGLAGHDLERLAQGLREVVEPGYLRARAASTARLARLINEAGVDT
                     VQPAGIHALYLNAGRLLPHLSPQEFPGHALGCQLYLDGGIRCAELGSLYLGGMDDQHRL
                     VTPAPFELVRLAIPRRVYTDTHLEYVAAVLADIAKEPGRVSGYRVVSSPPLLRHFKVRL
                     APIPAAGSTD"
     aSDomain        11307..12440
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS12120_Beta_elim_lyas
                     e.1"
                     /evalue="4.40E-69"
                     /label="GA0070216_RS12120_Beta_elim_lyase.1"
                     /locus_tag="GA0070216_RS12120"
                     /protein_end="427"
                     /protein_start="49"
                     /score="224.8"
                     /tool="antismash"
                     /translation="DLLSDSGTGATSAAQEAAAALGDESYAGARSWFRFRDEVHDLTGY
                     PHILPVHQGRAGERVLFTGLLKPGQLCLSNTHFDTTHANVKLAGAEPRDLPCPAAFDLD
                     SPDPFKGNIDLDALTRTLTGPERDRVGLVLMTITNNGLGAQPVSMANLTAVRDLCRRHE
                     VPFFLDAARFAENAWLVGQREPGYQDWTPRQIATHAFGLADGCVVSLKKDGLSAIGGLI
                     GLRDDDLHARCEANLIATEGFSTYGGLAGHDLERLAQGLREVVEPGYLRARAASTARLA
                     RLINEAGVDTVQPAGIHALYLNAGRLLPHLSPQEFPGHALGCQLYLDGGIRCAELGSLY
                     LGGMDDQHRLVTPAPFELVRLAIPRRVYTDTHLEYVAA"
     CDS_motif       11631..11798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070216_RS12120_0001"
                     /evalue="1.40E-01"
                     /label="C2_LCL_024-062"
                     /locus_tag="GA0070216_RS12120"
                     /protein_end="213"
                     /protein_start="157"
                     /score="4.7"
                     /tool="antismash"
                     /translation="FKGNIDLDALTRTLTGPERDRVGLVLMTITNNGLGAQPVSMANLT
                     AVRDLCRRHEV"
     misc_feature    11658..11660
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12668..13207)
                     /locus_tag="GA0070216_RS12125"
                     /old_locus_tag="GA0070216_10540"
     CDS             complement(12668..13207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020519293.1"
                     /locus_tag="GA0070216_RS12125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10540"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_245722458.1"
                     /transl_table=11
                     /translation="MKVVVAGGFGTGKTTLVGSVSEIPPLVTEEVLTQASIGVDDITGV
                     EGKTSTTVALDFGRITISNDVVLYLFGTPGQDRFWFIWDELAQGAVGAIVLVDTRRLGT
                     SFPAVDYFERRGIPFVAAVNRFYGECPYTEDEIRSALELDETVPLLWCDARDRASSKQA
                     LIELVRHALARLPATT"
     gene            complement(13242..13607)
                     /locus_tag="GA0070216_RS12130"
                     /old_locus_tag="GA0070216_10541"
     CDS             complement(13242..13607)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442378.1"
                     /locus_tag="GA0070216_RS12130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10541"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_091244117.1"
                     /transl_table=11
                     /translation="MTHDVWDGDDEAEAGRLVPLYILVNGRTSPRNTSLDLATQVIALP
                     ADQSRLELEYREILQQCNGWISIAEIGAYLHRPLTITKVMVDVLHEQGFLDIGSPAQEK
                     IADRWLLETVLAGLQRI"
     gene            complement(13604..14035)
                     /locus_tag="GA0070216_RS12135"
                     /old_locus_tag="GA0070216_10542"
     CDS             complement(13604..14035)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072006.1"
                     /locus_tag="GA0070216_RS12135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10542"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_091244120.1"
                     /transl_table=11
                     /translation="MTYSASQNDLTWILDDLVEVPDVVYAVVLSTDGLIVQKSTSLPQD
                     AGELLAAGASSLHSIAAGMGRRFDSGPVQQVIIEYEGRTLFVAAAGQNARLAVLCEQSV
                     DMGTVAYEMSRLVTRIGDYLGSEVRLDAMMLTDRPGLKP"
     gene            complement(14032..16440)
                     /locus_tag="GA0070216_RS12140"
                     /old_locus_tag="GA0070216_10543"
     CDS             complement(14032..16440)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020519296.1"
                     /locus_tag="GA0070216_RS12140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10543"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_245722459.1"
                     /transl_table=11
                     /translation="MIRLVLIPSVVALVVWLVASGYLIFQGFYNRQVANSVRQVSIPAV
                     SALSSIQQERRLSVSYLTQPSRDLSRLIEQRQQTDQLLAALRPVADSALAAAPDSIVTR
                     WETLAGLLDEMASVRSTIDSRSANGTGVYDFYNRVLDAATGLFDTQARIVPDVIAAQGG
                     IAATEAFRASDLMSRAGSTIDGAFGARTLSPEDHLDFTNLVGAYHAGLTNVAPHLEPEA
                     RRRYAEITASDSWKELVAAEKTLVSNGPWRSGAPRALPFNRAQWETLTRQVSDDLINLT
                     VVQADTVSARTLRTGNTQLLTASLGSLIALLVVIAAIIWAIRQSQILVDRALSVRLAQL
                     GRDAEAVVDKQLPAMMDRLRRREKVDLAAELPLQEYGSDEIGRVAEVINRSLQAAAGAA
                     VDEAKTRAAGIAMLMGVARRPQRPLQRGLKVIEDLQNRIGDEKLLAELFDINHQLTQTR
                     RFLENLVILAGGQIGRRFQNPVPVRRVLLAAFAEAQQYQRITLRSAPDVAVVGPAVAGT
                     VHLVAELLDNALAFSPPETTVWVTCIEVKRGIAIEIEDAGVGMRADALERANELLATAP
                     TPDVTALKDGAQVGLHVVAELAKRDGVQVSLRASAYGGLLAIVLLPDRVIATDPFTTDL
                     DRTDPGVLPLGTIATAMSRPGVGAVLPVGGGRRELHPAAGARPTAMVATAPSGAVQAPA
                     DPAGARQPDRIGGIMTDVPAQRGAVRSGAPGPQVADRPPLPHRRPQQHLAPELREEGLP
                     GQASDATPAAARSPEEARDRFTRYQKAWAAGRSAKTGDPASRDDQGRKA"
     misc_feature    16693..16707
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.65"
                     /tool="antismash"
     misc_feature    16711..16725
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(16743..16758)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            16897..17604
                     /locus_tag="GA0070216_RS12145"
                     /old_locus_tag="GA0070216_10544"
     CDS             16897..17604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007071634.1"
                     /locus_tag="GA0070216_RS12145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10544"
                     /product="hypothetical protein"
                     /protein_id="WP_091245216.1"
                     /transl_table=11
                     /translation="MLKAKWVTGVALLVCSGTLMACGDGAATPTGTASGSATPSGVATP
                     SGTVTPSGTALPADPATSPPTAAPSKSAGKPAATTSTAPVLSGKREVTIVRVQATESGV
                     SLDGGELVEVDDDSGRQLFVPTPAGAGKYLIKSYGKRDNHPASDDPACWQVVNPANGGS
                     LTVEGAACNSRKPAQLFTIASAGKGAYAISNNSAFLQFSPSRGLILEELGDAPLLSTFR
                     LVDNGPARTPAGG"
     gene            17745..18827
                     /locus_tag="GA0070216_RS12150"
                     /old_locus_tag="GA0070216_10545"
     CDS             17745..18827
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (62-225). E-value:
                     4.2e-11. Score: 34.4. Matches aSDomain:
                     nrpspksdomains_GA0070216_RS12150_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283508.1"
                     /locus_tag="GA0070216_RS12150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10545"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_091244122.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.9e-09, bitscore:
                     30.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIVIVGASGNVGTAVLRRLGREPGLDLVGVARRLPGPDAGAPYD
                     GVRWHSCDVGAPGAVDQLTAIFTQADAVVHLAWQIQPSHDQRTLHRTNVGGSRAVTEAT
                     VRAGVPALVYASSVGVYAPGPKDHPISERWPATGVPGSSYSRDKAEVEAMLDTVEAAHP
                     QLRVVRLRPGLIFQRDAGTEITRYFLGPLAPVRLLRHGRIPLVPAHRRLRMQAVHADDV
                     ADAYARAVLGEARGAFNVAADPVLTPELVARHFKGWTVPVAAPVLRAAAALTWRFRLQP
                     VDAGWVELGLNAPLMSSARAETELGWQPQVDAVTALRELFAGMAHGAHTGGPPMSGDAD
                     LPGRPAGLLRGRAPGQGDPY"
     aSDomain        17931..18419
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070216_RS12150_NAD_binding_4.
                     1"
                     /evalue="4.20E-11"
                     /label="GA0070216_RS12150_NAD_binding_4.1"
                     /locus_tag="GA0070216_RS12150"
                     /protein_end="225"
                     /protein_start="62"
                     /score="34.4"
                     /tool="antismash"
                     /translation="LTAIFTQADAVVHLAWQIQPSHDQRTLHRTNVGGSRAVTEATVRA
                     GVPALVYASSVGVYAPGPKDHPISERWPATGVPGSSYSRDKAEVEAMLDTVEAAHPQLR
                     VVRLRPGLIFQRDAGTEITRYFLGPLAPVRLLRHGRIPLVPAHRRLRMQAVHADDVADA
                     "
     gene            complement(18936..19685)
                     /locus_tag="GA0070216_RS12155"
                     /old_locus_tag="GA0070216_10546"
     CDS             complement(18936..19685)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473496.1"
                     /locus_tag="GA0070216_RS12155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10546"
                     /product="ZIP family zinc transporter"
                     /protein_id="WP_091244126.1"
                     /transl_table=11
                     /translation="MPEWWQAGAWGLLAGSALLIGAAVGFFVRVPRMVVASIMAFGAGV
                     LLSAVSFELIAEAHEQGGLLPTVIGATGGALAYTGANVLLARRGARHRKRSGGEQPSEQ
                     EQPGSGSAIAVGALLDGVPESVVIGASLLTGGPVSLVTVVAVFLSNVPEGLSSAAGMRR
                     AGRSRRYVFALWTAITLISGIAALLGHTLLGGAPPEVLATITALAAGAILAMITDTMVP
                     EAFEDAHLLVGLITVLGFLTAFALSHA"
     gene            complement(19785..20993)
                     /locus_tag="GA0070216_RS12160"
                     /old_locus_tag="GA0070216_10547"
     CDS             complement(19785..20993)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283511.1"
                     /locus_tag="GA0070216_RS12160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070216_10547"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091244129.1"
                     /transl_table=11
                     /translation="MLIRRLAAEERLTTSFPLQAYAFEASPLSRERVEAFHRYLPYNKG
                     NRTLVVEEGGVARATASAVPMRQNLRGAVLPMAGVAGVATHPLARRQGYVRALLRQLLD
                     EMRDGGHPVSALYPFRASFYERFGYVGLPRARTARFSPADLAPLLGAELPGTVTWERIG
                     PGYARYRSFTERCLRERHGFAIFPEFRDVGMRDRDDRWLITATIDGSVVGALTYRIDDH
                     GGELAGDDLLAADPYARALLLQFLARHVDQVERISLQLPADDLPELWLTDLAVHVEARV
                     TRPGSPAPMARLLGVDALAGLPAGPGRVRVELVDDRWLAGTHLLDGASGRLELTSGGRS
                     AVTSGAAVPEVTLTAAGLSALAYGVLDPAEVHIRGLGDVGPEAAAALRRIFPRALPYLF
                     ADF"
     misc_feature    21111..21126
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.47"
                     /tool="antismash"
ORIGIN
        1 gtggtcggta cgtcggtctt gccgcgcgcg tggtcgacgg ttctggtgtc gccgacgctg
       61 cccgccgggt cggagtcgtc ggagccgcag gcggccacgg cgagcacggc cgccgaggcg
      121 acggtgaggg cgagaagacg tcggcggatt gttcgagggg ctggcgtgcg catggtgcga
      181 ggttcccgtc tgactactta cggtgattgc tcactaacgt ttttaggtta gcattaccta
      241 atcatctatc tcgtcgcggg ccgggcggtc atgccaatac ccctgggtgt ggacctgttc
      301 cggatcgacg cctgcctcgg tgaagagtcg gcgcacctcg gcaatcctgc tactctccgt
      361 agctgtccag gcgtagaagt tcgcctccgc cgctgccgcc gccaagccgt gcccggccag
      421 ccagtcaccc accatggcgg tcagaaccgt cccgcccgga gcgccaccgc gcaaccggac
      481 ctcgaccggg tggccggcgg tcacgtcgtc gagggtggcg gcgtccgccg cggtgccggc
      541 ctccaacagg accgttgccc gcacccccgg cccgaggctg ggcaggatgc cgcgcaccgc
      601 cgggtacgcc gtctcgtccg ccgcgatcag cacccgcgtc gccggccccg gctcccactg
      661 cacgccgtac ccggggtggc cggccccgac gtgcgggccg gacaggagca gccggtcacc
      721 cggacgggcc gccgccgccc agccgctcgc cgggccgtgc ggctggtgca ggtagaagtc
      781 caggtccagc tcgcccgccg ccgggcgcgt ccggtacgcc gtgtaactgc gtagcctcgg
      841 ccgctcggga ttcgggatgg cccgccactc ccgccgccat tcctgttcgg gcagccccgc
      901 ccgcagttcg gtcgggtagt cgccggccac cggcagcatg atcttgatgc gctggtcgag
      961 gtggtgcggg gccaactccc gcagtcgttc gtcgccgagc gtgatccgga cgaacccggg
     1021 cgacagccgc cgggtcgccg tcacggctgc ctcgaacagg acgttgggcg agttgcggaa
     1081 ggcggacatg ccggcagagg ctagccggtc ggatccggcc cgttcgccgc cccgcagggc
     1141 gtatccaggg cagcagagcg ggagcgtgcg cgagacattg acgatgttga ggtaggtggc
     1201 ccaatcttga cgccacccgg gtcaggaaga ccgggtttct catcgggtcg gcggaggagt
     1261 gctcatgcca cacatcacgc tcaataccag tgaacccgga attcgcggcc tgttccggtt
     1321 caggccggag acggcactac cactgaacgc gctggtggag gcgctgctgt gtggcccggg
     1381 cacgttgacc cggggcgaaa gggaactcat cgcggcctat gtgtccggcc tcaacgaatg
     1441 ccggtactgc tactccgccc acgcggcgta cgcggcagcg cagctccccg agggcatgac
     1501 cctggtcgag caggtgcacg acgacgtgga cagcgcgccg gtgtcggcca agatgcgcgc
     1561 gctgctcgac gtggccggcg cggtgcagcg gggtggccgg gaggtcaccg aggacctggt
     1621 gaccgccgcc cgggccgagg gcgccaccga tgtggagatc cacgacaccg tgctgatcgc
     1681 cgccgcgttc tgcatgttca accgctacgt cgacgggttg gccaccgtgc tgccggacga
     1741 cccggacttc tacaccgatc gcgcacagcg gatcgccgcc cacggctacc tcggtgtgct
     1801 gcaacaggag gtcatccgcg agtgaccggc ccggcaggcc cgtgggcgtc ggcacgccgt
     1861 cagcgggcct gccggagcgc gtcggccagc tcggtcgccg tggtcgcggt gacccggggt
     1921 tggtcgacga gcatctggtc gatcaccccg gccagcctcg gcggcacggt gccgagccgc
     1981 tgccgtacag gcaccggccg ggtacgcagg accaccgcca ccgggtcgac cccgaccggg
     2041 aagtcccggg gggtcgcccc cgtcagcatc cagtagagac aggcggtgac cgcccagagg
     2101 tcgacctccg ggcgggcgta cttgtagtcg atgagttggg cgcgggcctg gaaggcgatg
     2161 ctgccgccga tcgcgccggt cccggtgtgc ccggacaggc ccgccttctc gaacgccttc
     2221 gcgagcccga agtcggcgac cttggtgatc acctcgccgt cgggcccggt ggcgagcagg
     2281 aggttctgcg gcgtgacgtc ccggtgcacc aggccgtggg cgatctccgt ccggccgtcg
     2341 gccagcacga ccgcaagctc cgcccggtgg gcgtaggcca gtgcatccaa cgcgtcgagg
     2401 gtgatcggca ccgcctcgtc ggcggtgagc cggccaccgc gccgggcgac gaactcggcg
     2461 acactgccac ccgggcagta ttcgctggtg aagaagaagg cgtcgtcggc cgcgccgccg
     2521 ctgtgcaggg cgacgacgtt gcggtgccgc agccccctgg tgcaggcgat ctcgcggcgg
     2581 aaggcgtcgc gtgcggccgg gtccacggcc cggtcggcga gcagcgtctt cagcgcgacg
     2641 agccggccgg acggctcgtg gcgggccagg tagacgacgc tgtggccacc ccggccgatc
     2701 tcccgcagca cccggtggtc ggtgaagtcg tcgaggccgg gggccccgtc cgccgcggcc
     2761 gacaccagca ccggcagggc ccgcccccga tccgggccgg gggtcccggt gtccggggtg
     2821 gtcggcgtgg tgccggcggg ggtggccccg gtgtcttccg gtccggcagc ggcttcccgc
     2881 gtcccgtcgt cgggcagggt gacgcgcaac gtcgcaggcc cgatccgcac ctcgtcaccg
     2941 gccgacaggt gccgctcgcc gtcgaccggg cggccgttga ggtgggtgcc gtggcgactg
     3001 ccgaggtcgc gtacccgcac gttcggcggg tcgatgtcga gctggcagtg ccggcgggag
     3061 acccgccgct gcccgtcgtc gacccggatt ccgcagtcgg cggcccggcc caccacgacc
     3121 gtcgtgcggc ggtggaagac gtacgtgtcg acggtggacc cggcccggac ggtcaccgtg
     3181 acgggcgggg taaccggcac cgccccggcg ggtcgcccga ccccggggtc gtcggtgccc
     3241 acgcccggct gcccggtcag tcgaccagcg ccacgtacag cgggctgccc agcagcacgg
     3301 tcatgccggg acgcccgtcg agttccgggt acgggctggg cccggagagc agccgcttgg
     3361 cgaggaactc gacgttctgc gtcggccccc gcaggcgggt gccggcctgg tgcaccgacg
     3421 ccagcgccgc cacctccgcc gcgtcgtccc cgccgtccgg ggtgcccggc accggttcgg
     3481 ccccgtcatc gacgaggccg gcgagcagcg cgggcatcgt ggacgacccg ccgaacccgc
     3541 gcagggtcgg ctcgggcggt gccgcgccga tgacgtggaa cggtgacccg ccgagaccga
     3601 cgatggtgtc ctcggtgcgg ccaccgaagt agaccagcga ctgctcgtcg gtggtcggga
     3661 cgatgcccca ccgcatcggc agcagtcccc ggaagaactg ccccggctcc tccacggaac
     3721 cgacgtcggc gtgctcgtcg agatagcggg cgacccgctc caggcgggcc acccgatcgg
     3781 tgccggggtt ctcggtgctg cgtttcacgc cgacgacggt gaggttcaca ctgaactcgg
     3841 cggcccgcct gcgctgatag ccggggtcga tctgggacaa cagcatgtcc accttggcgt
     3901 cactgacgta gaggtagtaa cgaaagctca cggtcactcc ctgacgaccc ggtccggcat
     3961 ccgaggttac cgtccgcgac caaccgacag ttgtcccgtg cgctgcgggc tgccaggctc
     4021 ggaccatgcc gtggcgtccc ggagagctga tcctggatct ctacgaggtg cgcgaccagc
     4081 ccctcgccgg tggcatgggc ctggtctacc gggtccggca ccggggctgg gacaccgacc
     4141 tcgccgtcaa ggtgccgcgc cccgagcaac tgaccaccga ggcgcaccgt gcccggttcg
     4201 aatccgaggc gggcacctgg gtcgggctcg ggctccaccc ccacgtggtc agctgcgcgt
     4261 acgtgcgtcg tgtcgacggg ctgccctgcg tgttcgcgga gtgggtggcc ggtggctcac
     4321 tggaccaggt ggtccgggcc gggcggctgc acgaggggcc gggcggcccc gacggtggat
     4381 tcctcgcccg ggcgctcgac ctcgcggtgc agtcggcgtg gggcatcgac cacgcccatc
     4441 agcagggcct catccaccag gacgtcaaac ccgcgaacat catggtcggc ctcgacgggg
     4501 cctggaccgc gaaggtcacc gacttcgggc tggccggcgc ccgggccgcc gtcgacgggg
     4561 tcgccggcac agcggtggag gccagcctgg gagcgagttt cggcggcatg acccccgcct
     4621 actgctcgcc cgagcaggcc gaggcggcgg ccggtgcgcg ggtcacgctc acccgggcca
     4681 ccgacgtctg gtcgtggggc ctgtgcgtgt gggagatgtt cgccggccgc cgcccctgcc
     4741 gctacggtca ggcggcgcgg gaggccttcg ccgactacct ggcggcgggg gagacctggc
     4801 cggccgccca gccgatgccg ccggggatcg tcgacctgct ccggcggtgc ttcgacgtcg
     4861 acccgacgac ccggccgcac cacctcgccg acctggccac ggcggtcgcc ggggtgtacg
     4921 ccgacaccgt cggcgtcccc tatccacggg tgccgccgtc ggcggcgggc ctgctcgccg
     4981 gcagcctctc caaccaggcg ctctcgctgc tcgacctcga ccggccggag gattcggagc
     5041 acctgtggcg caacgcgatc gacatcgacc cgcaccaccc cgccgccgtc tacaactggg
     5101 cgctgtaccg gtggcggcgc gggcggatca ccgacgaaca ggtgctggcg gagctgcgga
     5161 cggcccggga gatcgccggg gagaactggc aggccgacca cctgctgggg ttcgtgcacg
     5221 ccgaacgggg cgacgacgag gcggcccggc ccttgctggc cgcctcgtcc accaaccccg
     5281 acgtcgccga ggtggccggt gccctcgccc ggcgcggcac ggcacccggg ccgcagcgtc
     5341 tgcccggcca ccgcggccag gtgaccgccg tcgccgtcga cgagagcggg cgggtggcgg
     5401 tcaccggcgg taaggacgga agcctgcgga tctggtcgct gaccgagaac cgggcggtcc
     5461 gcgaactcgg tacggacggc gcgggtgccc cggtcacgac cctggcgatc gaccctgccg
     5521 gccgtaccgc gctcgtcgcc cgcgaggggg gtcggaccga acgttggaac ctggcccggg
     5581 tcgggtgcgt caccgtgccg ctcggccagc gggcggccgt gaccgcgctg gcgctgacga
     5641 cttcgggcgc tgccgccatc gggtacgaca acgggcggat cgaggtgtgg gacacgaccg
     5701 acgggcggct gcggcgcacc ctggagcacc cgccgagcac ctaccagcgg ctggacccgg
     5761 cgacgggccg gatcctgccg gagatccagg agagtcccgc agaggtcacc gtgctgggcc
     5821 tgagcgagga cggcacggtc gcggtgtcgg cggcgccccg ggacggcagt gtggtggtct
     5881 gggaggtcga caccgggcgc tggctgcacc gcctggtcaa gtccgccgac atgcggatga
     5941 ccggggtcga cgaggtggca ttgggcgggt ccggcaggta cgccctgctg atcgggcacc
     6001 agacacgggt ggcgcacctg tgggagacca ggccccaccg ggtgcggggg ccggtgccga
     6061 acaacctgaa ccggtactcg acggtcgtgc tcagcggtga cggcgaacgg gcggtctcgg
     6121 tcggggtcgg cagtcccgac caaccggtgc ggatctggga gacggattcc ggccggtgcc
     6181 tgcgtaccgt cgccacgcgt atcgacgggc tgcgaccgga gatggccggt ctgctgtcgc
     6241 tcacctgtgc ggcgaccagc ggcgacggcg cgctggtcgt gctcggggac gagtacgggg
     6301 ggctgcacgt ccaccggctg ccccgccccg acctgcgcgc accgtggagt tacgagcggc
     6361 cgctggcggc gagggcggtg ctggcggccg aggcgcaggt ccggcaacgg gtcgtccgtg
     6421 cggagtcgct cgccggggag ggccggccgg ccgccgccgc cgtggagcta cgggccgccc
     6481 gggacatggt cgggttcgag cgtcacccgc agctgcggga gctgtgggag cggttggggc
     6541 ggacggcggg cgagcggacc gcgccactgg gcgtctggca gcgctacgag ctgcgcggcg
     6601 gcgagttcac cttcgtcccc gggctggccc cggcgctgag tgtcgacggc gagctggcgg
     6661 tgacgggcgg tgccgacggc ctgctccggg tgtgggagct gcggaccggc cggcaacggc
     6721 acaccttcgc ggagcgggtg ggcaaggcgc acacggtcgt gctttccgca gatgcccagc
     6781 tcgccctcag cgcggactgg gccgggaccg cgcacctgtg ggacctggcg gccggccggc
     6841 ggcaggccga gctgcacggc gaccacggtg cggtgcgggc ggtcgcgatg gacggcacgg
     6901 gccggtacgt gatcgtcggc gacgccgacg ggaacctgtg cctgtggagc ctgtaccggt
     6961 tccacctgag ccgcaccatg gtggcgcacc gggggccggt ggggtcggtc caactcagcg
     7021 acgacggtcg gtatgccgcg tcggtcggtg cggaggaccg gacgtgccga ctgtggcgca
     7081 cgggcaccgg cagcccggtg ctcacgatcc ccgtcgagtt cgggtcggta ccgctgcggt
     7141 tcaccccgga cagcaggcag cttctgatca actcgccggg ggaactgacc gcgtgggacg
     7201 tgcagaccgg ccggcagcgg tacgccttgc cgagccgggg tgacgccatg gcgctgagcc
     7261 gggacggacg ggtcgggctc gtccgtgcgt acgacgagtc gtacgggcgg gtggtgtcgg
     7321 tgtgggagac ggcgaccggg cgggtgctgt gcgaactggc ctccgaggcg aaggtgttcg
     7381 acgtgagccc ggacggtcgt catgcggtga ccgccgatgt ggaccgtacg ctgggcatct
     7441 gggacgtccg gacgggacga cgcgtgcaca cgtgcgacgg tcatccggag ccggtgtcgt
     7501 ccgtggcctt cacggcggac ggccggagca tggtgtcgat ggacagccgg ccggcgatcc
     7561 ggcggtggga gctggactgg gactacgact tcacgggctg acccgcaacc gggcggagcc
     7621 gagccgggtg ctgagcccgc cgcccgtcac cggctccatc ggctggtcgg tgtacgccgc
     7681 cgcgcgcagc gcgtcgtcgt gggcggcccg ttgcttgcgg gagaaccggc tgcggtcgac
     7741 cgcgaggtcg gccacgaccg gcgggatgag atcccggaac tcctgcggca ccccggcgat
     7801 gtggcgttcg tagtggggat cgtccgggta gctcagcgtc agggtgaccg gtggctcgcc
     7861 gcgcagccga ccgcccaggg cgcgcaggga accggccagg aactccaggg cgatgttcac
     7921 gtcacccgac aacgtgatgt tgttggactc cggctggtat ccgggcgggg cgtcctcggg
     7981 caccacgaaa cgtacggtga cccgcttggc gggcaactcc agcagcaggc ggggccaggg
     8041 tccgccgccc tcgatggtca cgtccacccg ctggggatcg acggacagcc gcaggctgag
     8101 ccagtcgatc atcgccaggg cctcgggcgg caggtcgtcc tgacggtacg ggccccggct
     8161 gcgggtccgc agggcgtgcg cgtgcatggt ggtcagcacg cgcgccccgt cgccgtcgat
     8221 ctccagggag agcgggtgga ccgccaggtc ccgcatgacg cggacgacgg cgtcgatcag
     8281 cgcggatggt gccgaggcgg gagccatcgt ccacctttcg ctccgtgtgg gatcggtgtc
     8341 gcaccgtgtc agccagtgtc gcacatgaat gttttcggca ctgccgccgg ccggcggacg
     8401 gcgtacgcga tgatccgcgc tgcgcaccca ccgccgctcg cggatcgtcg tcgacgcccc
     8461 ggaggtggcg gtcaggacgg tgggccgccg ccggcccgtg cacctcggcg acggcggccg
     8521 ccgcatgacg taccccgctg gctcgtgggt ggaagcgggg gtcaggcggc caggcggcgc
     8581 gcgagcgcgg ggaccacgat ggcggccgcg accaggtggg tgaggatcag cagtgccttg
     8641 gtcgccgctc cggcgtcgat gagcaggtcg ggcaccagcg acagggcggt cagcaccacg
     8701 gtgacgagga cgaacgttcg ccgcggacgc cgggcgaagc gggccagcag cacggcgaga
     8761 agcacgccga ccagcgagaa ggcggcggtc agcaggccga atcccgagag cggaatcgta
     8821 tcgtcgccca cgccgaggct gatcccggcc gcgtggccgg cggcggcgac ggccacggtg
     8881 gcgacgctcg cggcagccgt agcgatcacc ccggtcagga tcagcgcacc gatggcggac
     8941 ctggtggcgt ggggcgggtt cgcagcggtg gtcatcgtgc ctccaacggt gggccgggcc
     9001 ggcccggtgc ctgacctctc atcagaacga cgaacgggac gaacctcaat cgacaggcac
     9061 gcccaggttc ttcgtccgtt gtgacgcctg gctattgtca gcccacaact ccatcgagga
     9121 gtctcattgc atgggggaac agatgatctc tcggcgcctt cgcgcgcttt ccgccgccgt
     9181 ggcagccgcc acggtcgctc tgtcgatcgc gactccggcc atggcggcac cggccaccgg
     9241 gccggttctc gacatcacgt cgatcgcctt cgaccgtccg caggtcgacg tcaccgagga
     9301 ctacgccgcg gtcagcctga cgtggacgac caccgaccgg gctgccgggg cgggaacgtc
     9361 gcgttctacg gcacggccca cggtgctccc gacctcggcc tgaccgttac ccaggtgccg
     9421 gacgagaagg cgccggtggt gttctcggcg aggttgccca aggcgacccg gacgtcccag
     9481 gagaccgcag acgcgtgggg tctcggcttc gacgtcacga tcgaggtcga cgagttcgcg
     9541 ccgatctcgt cgaccagcgc gacgaactat gacagcacgg gggcttcccg gggcggcatg
     9601 tacgggagcc ggcacgacct gacagcccgg acgacccgcc ccctgtgggc cgggccgtcc
     9661 gggacagtgc gggcgaggac cgcggtgccg gtccggcccg agggctttcc ttgggtccgg
     9721 ggcactgccc tgccgcaatg ctcgactgtc aggccgacgc cacccggtgc cggcctgacg
     9781 gctttggcgg caacccgccg ggtggaaacc ggggacggca ctccgcggcg atcatcaaca
     9841 ccatgtgacg tatcctgcac gcgactctgg gtgattgtca gaggtgattt gccggtctcg
     9901 atcctgttat gtcattgcaa gttgtgatca atcttgacct tgttgcgaaa tgcttcttag
     9961 ggtctctttt ggtcgtcggc ttgatcggga gagagaactg atggacgaag tgtccctttc
    10021 cgatcgtctg agcgaccagc tgaggcgttt gtgcgaggtc agcgggatca gtgcggcgga
    10081 gccgctggaa ctgctggaaa gcctgctcgg accggccggc ccacagccgt tgtcggcccc
    10141 gccggggtgg ccgtccaacg tcgcggacga ccacactccg gtggagttct ccatcgcctt
    10201 cagcgcgacc gaaccgccca ccgtgcggat tctgggcgag acgttgggga caccacccgc
    10261 ccggttgacc aacatgctcg ccacccagcg gttcctcgac cggcaggcac accgcgccgg
    10321 cctgtccacg tcccggctgg attcggtgcg cgacctgttc gccacctacc acccgcaggg
    10381 caccttcgcc ctctggtgct cactggtctt ccgcagcggc cggcgacccg agttcaaggt
    10441 ctacctcaat ccggagctcc gggggatcga ccgggcaccg gccctggtct ccgaggcgct
    10501 gcaccgactc ggactgggca ggtcctaccg ggcgatgctc gaccgcagca tccgtccggg
    10561 cgagctgggt caccgggacc ggctgacgtt cttcgccctc gacctgcatg acggcgccca
    10621 ggcccgggtc aagctctacc tgacccacca tgacgcctcg gtgcgggacg tcgtccgggc
    10681 ggccggcgtg gtccacgacg tggatgcgac ccgcctcgcc gagttcgccg cgctggccgg
    10741 tggcggccgg acccggttcg ccggtctccc gctggtcggc agctacaccc tggtcgaggg
    10801 ggtcgaccgg ccggtcggct acagcctcta cgtgccgatc cggggctacg tcgaggacga
    10861 cgaggaggcg tacgaccggg tggtggcggt gctggaccac tgcgggttcg accacacggt
    10921 gctggatcgg gcgctcgccg cggtggcccg ccggccgctg cgcgacgggg tcggactgat
    10981 cccgcacctg tcgctgcgga tgggcgctcc ccggccgggg gtgaccgtct acctgtcggc
    11041 cgaggcttac caggtgagcc cgccggtgcg ccacccgtgg accgtggacg gtgcggcact
    11101 ggcggctccg accggccgtg ccggcgcggg acacccctga ttccatcgag gagcgaactg
    11161 tgtccgtgga cctgcaccag atgttgcccc cgtaccggat caaggtggtc gagccgatcc
    11221 ccttcctcag cccgcaggag cggcgggcgg ccctcgcgga ggcgggatac aacccgttcc
    11281 acctgcgcgc cgaccagatc accatcgacc tgctgtcgga ctccggcacc ggggccacct
    11341 cggccgcgca ggaggctgcc gccgcgctcg gcgacgagtc ctacgccggg gcgcgctcct
    11401 ggttccggtt ccgcgacgag gtccacgacc tcaccggcta tccgcacatc ctcccggtcc
    11461 accaggggcg ggccggtgag cgggtgctct tcaccgggct gctgaagccc ggccagctct
    11521 gtctcagcaa cacccacttc gacaccaccc acgccaacgt caagctggcc ggggcggagc
    11581 cacgggacct gccgtgcccg gccgcgttcg acctcgacag cccggacccg ttcaagggca
    11641 acatcgacct ggacgcgtta acgcgcaccc tcaccgggcc ggagcgggac cgggtcggcc
    11701 tggtcctgat gaccatcacc aacaacgggc tcggcgcgca gccggtgtcg atggccaacc
    11761 tcaccgccgt ccgtgacctc tgccgccgcc acgaggtgcc gttcttcctg gacgcggccc
    11821 ggttcgccga gaacgcctgg ctggtcggtc agcgcgagcc gggctaccag gactggacgc
    11881 cacggcagat cgccacccac gccttcgggc tcgccgacgg ctgcgtggtg agcctcaaga
    11941 aggacggtct gtcggccatc ggcgggctca tcgggttgcg cgacgacgac ctgcacgccc
    12001 ggtgcgaggc gaacctgatc gccaccgagg gcttctccac ctacggcggg ctggccggcc
    12061 acgacctcga acggctcgcc caagggctgc gcgaggtggt cgaacccggc tacctgcggg
    12121 cccgggccgc ctccaccgcc cggctggccc ggctgatcaa cgaggccggg gtggacaccg
    12181 tccaaccggc gggcatccac gccctctacc tcaacgccgg ccggctgctg ccccacctgt
    12241 caccgcagga gttccccggc cacgccctcg gctgccagct ctatctcgac ggcggcatcc
    12301 gctgtgccga actgggctcg ctctatctgg gcgggatgga cgaccagcac cggctggtca
    12361 ccccggcccc cttcgaactg gtgcgcctgg ccatcccgcg ccgggtctac accgacaccc
    12421 accttgagta cgtggccgcc gtcctcgccg acatcgccaa ggaacccggg cgggtatccg
    12481 gctaccgggt ggtctcgtca ccacccctgt tgcgccactt caaggtgcgg ttggcaccga
    12541 tcccggcggc gggcagcacc gactgatccc gctgcgacgc ggtggctccg gtacgcccac
    12601 gtggtggacc ggcgtcaccg cgcgccacac aggcagaggt ggtggagtgg ggctccgggc
    12661 tcgccgctca ggtggtggcg ggcagccggg ccagggcgtg ccgcaccaac tcgatcaacg
    12721 cctgcttgct ggaggcccgg tcccgcgcgt cgcaccacag cagcggcacg gtctcgtcca
    12781 actccagcgc gctgcggatc tcatcctcgg tgtaggggca ctcgccgtag aagcggttga
    12841 cggcggcgac gaaggggatg ccccggcgct cgaagtagtc gacggcgggg aagctggtgc
    12901 cgagcctgcg ggtgtcgacc agcacgatcg cccccaccgc gccctgggcc agctcgtccc
    12961 agatgaacca gaaccggtcc tgccccgggg tgccgaagag gtagagcacg acgtcgttgc
    13021 tgatggtgat ccgaccgaag tccaacgcga ccgtggtgct cgtcttgccc tcgacgccgg
    13081 tgatgtcgtc caccccgatg ctggcctggg tgaggacctc ctcggtgacc agtggcggaa
    13141 tctcgctgac cgatccgacc agggtggtct tgccggtgcc gaagccgccc gccacgacga
    13201 ccttcaccga tttccgatcc acgtgtatca gtccctcttg tctatatccg ctggaggccg
    13261 gcgagcaccg tctccagcag ccaccggtcg gcgatcttct cctgtgccgg cgagccgatg
    13321 tccagaaaac cctgttcgtg gagcacgtcc accatcacct tggtgatggt gagcgggcgg
    13381 tgcaggtagg caccgatctc ggcgatggag atccaaccgt tgcactgctg gaggatctcc
    13441 cggtattcca gctccagccg ggactgatcg gccggcaggg cgatcacctg ggtggccagg
    13501 tcgaggctgg tgttccgggg gctcgtccgt ccgttgacga ggatgtagag cggcacgagc
    13561 cggccggcct ccgcctcgtc gtcgccgtcc cacacgtcgt gggtcatggt ttcaacccgg
    13621 gtcggtcggt gagcatcatg gcgtccaggc ggacctcgga gccgaggtag tcgccgatcc
    13681 gggtcaccag gcgactcatc tcgtacgcga cggtgcccat gtcgacggac tgttcgcaga
    13741 gcaccgccag ccgggcgttc tggccggcgg cggcgacgaa cagcgtccgt ccctcgtact
    13801 cgatgatgac ctgttggacc ggcccgctgt cgaaccgtcg gcccatgccc gccgcgatgc
    13861 tgtgcaggga cgacgcgccg gctgccagca gctctccggc gtcctgcggg agcgacgtgg
    13921 atttctgcac gatcagcccg tcggtggaca ggacaaccgc gtagacaacg tcagggacct
    13981 ctaccagatc gtccaggatc caggtcagat cgttctgcga tgccgagtag gtcatgcttt
    14041 cctgccttgg tcgtctctgc tggctgggtc cccggttttc gccgaccgac cagcggccca
    14101 ggccttctgg tatctggtga accggtcccg ggcctcctcg ggtgaccgcg cggcagcggg
    14161 cgtcgcgtcg gacgcctgac cgggcaggcc ctcctcgcgc agctcgggag cgaggtgctg
    14221 ctgcggccgt cggtgcggca ggggcggccg gtcggcgacc tgggggccgg gcgcaccgct
    14281 gcggaccgcg ccccgctgcg ccggaacgtc ggtcatgatg cccccgatgc ggtcaggctg
    14341 tcgggccccg gcgggatcgg ccggcgcctg caccgctccg ctcggtgcgg tggccaccat
    14401 ggcggtgggc cgggccccgg cggcggggtg cagctcccgt cgaccaccac cgaccggcag
    14461 caccgcgccg acgccgggac gcgacatcgc cgtggcgatg gtgccgagcg gaaggacgcc
    14521 cgggtcggtg cggtccaggt cggtggtgaa cgggtcggtg gcgatcacgc ggtcgggcag
    14581 cagcacgatc gccagcagac cgccgtatgc cgaggcacgg aggctcacct ggacgccgtc
    14641 ccgcttggcc agctccgcca ccacgtgcag gccgacctgc gcgccgtcct tgagtgccgt
    14701 cacgtccggg gtgggtgcgg tcgccagcag ctcgttcgcc cgctccagcg cgtccgcccg
    14761 catgcccacg ccggcgtcct cgatctcgat cgcgatgccg cgcttgacct cgatgcaggt
    14821 gacccagacc gtggtctccg gcggggagaa cgccaacgcg ttgtccagca actcggccac
    14881 caggtggacg gtgccggcca ccgccggccc gacgaccgcc acgtcgggcg cgctgcgcaa
    14941 cgtgatgcgc tggtactgct gggcctcggc gaaggccgcc agcagcaccc gccggaccgg
    15001 caccgggttc tggaagcgcc ggccgatctg gccgccggcc aggatgacga ggttctccag
    15061 gaaccggcgg gtctgggtga gctggtggtt gatgtcgaac agctccgcca gcagcttctc
    15121 gtcaccgatc cggttctgca gatcctcgat gaccttcaga ccgcgttgca gcgggcgttg
    15181 cggacgacgc gcgacgccca tcagcatcgc gatacccgcg gcccgggtct tcgcctcgtc
    15241 gacggccgcg cccgccgcag cctgcaacga gcggttgatg acctcggcga cccggccgat
    15301 ctcgtcgctg ccgtactcct gcaggggcag ttcggcggcg aggtcgacct tctcccggcg
    15361 gcggagccgg tccatcatgg ccggtagttg cttgtcgacc accgcctcgg cgtcccgacc
    15421 cagctgggcg aggcggaccg acagtgcccg gtccaccagg atctgcgact ggcggatcgc
    15481 ccagatgatc gcggcgatga cgacgagcaa tgcgatcaga ctgcccaggg aggcggtcag
    15541 gagctgggtg ttgccggtgc gcagcgtccg ggccgagacc gtgtcggcct gcaccacggt
    15601 gagattgatc agatcgtcgg agacctgtcg ggtgagggtt tcccactggg cccggttgaa
    15661 cggcaacgcg cggggtgcgc cggaacgcca gggcccattg ctgaccaggg tcttttccgc
    15721 cgcgacgagt tccttccagg agtcgctcgc ggtgatctcg gcatagcgtc ggcgggcttc
    15781 cggttccagg tgtggcgcca cgttggtgag gccggcgtga taggccccca ccaggttggt
    15841 gaagtcgaga tggtcttccg ggctgagggt gcgggcgccg aaagcgccgt caatggtgga
    15901 accggcccgc gacatcaggt cactggcgcg gaacgcctcg gtcgccgcga tgccaccctg
    15961 ggcggcgatg acgtcgggga cgattctcgc ctgggtgtcg aagaggccgg tcgcggcgtc
    16021 gagcacccgg ttgtagaaat cgtagacacc cgtaccgttg gctgaccggg aatcgatggt
    16081 gctccgcacg ctggccattt cgtccagcag gccggccagc gtctcccacc gcgtcacgat
    16141 cgagtccggg gcggcggcca gcgcggagtc ggcgacgggg cgcagggcgg ccagcagttg
    16201 gtccgtctgc tgccgttgct cgatgagccg gctcaggtcc cgggacggct gggtcaggta
    16261 gctgacgctc agccgccgct cctgctggat cgacgacaac gcggagaccg ccgggatcga
    16321 cacctgccgg acgctgttcg cgacctggcg gttgtagaaa ccctggaaga tgagatagcc
    16381 ggaggcgacg agccagacga ccagggcgac gacgctggga atgagcacca gcctgatcac
    16441 gcgtcgtttg attgactgcg gtcgaccggc acgccgaccc gatgtcgtcg ggggggcctg
    16501 atcgtctgag gcgcggcgcg ggtcttcgcg gtcggcctgt ttgtgcgcca agtcgtcgta
    16561 tccaatcctg gtcaagccat caacaccggc agtcctgcgc cactggtcga cgccgatgtg
    16621 tgccaaccct accgtctatc cggtcccgca ccgggccacg attcgacgac tgtggacggt
    16681 cgcgccattc gcactggtca gacattcggg atgagttgca tcgatcacag ccccggtaat
    16741 gacgtgacgt gtgtcactgg agagtgggtg ggaaccggcg aaaccggcgg gtggtcaccg
    16801 gcgtccagtc tgttgctgcg gtgccatcac cgccggcgtg aggctcaagt ggacgacccc
    16861 cgcgaacacc cgcggggccg ggtggaggag cacgggatgt tgaaggcgaa gtgggttacc
    16921 ggggtggcgc tgctggtgtg ctccgggacg ctgatggcct gcggggacgg cgccgcgacg
    16981 cccaccggca ccgcgtcggg cagcgccaca ccgtcgggcg tcgccacccc ctccgggacg
    17041 gtgacgccca gcggtacggc actgcccgcc gacccggcga cgtccccgcc gaccgcggcc
    17101 ccgtccaagt ccgccggcaa gccggcggcc acgaccagca cggccccggt gctgtccggc
    17161 aagcgggagg tcaccatcgt ccgggtgcag gcgaccgagt cgggggtgtc gctggacggt
    17221 ggcgaactgg tcgaggtcga cgacgacagc ggacgccagc tgttcgtgcc gacgccggcg
    17281 ggtgccggca agtacctgat caagtcgtac ggcaagcgcg acaaccaccc cgccagcgac
    17341 gacccggcct gctggcaggt ggtcaacccg gccaacggcg ggtcgctcac cgtcgagggg
    17401 gcggcctgca actcccgcaa gccggcccag ctgttcacca tcgcgagcgc gggcaagggc
    17461 gcgtacgcga tcagcaacaa ctcggcgttc ctccagttct cgcccagccg tggcctgatc
    17521 ctggaggagc tgggcgacgc gccgctgctg agcacgttcc gcctggtcga caacggtccg
    17581 gcccgtaccc cggccggcgg ctgacccacg accgggccgc tgccggtggc ggcccggccc
    17641 ggcggcgggt cggcggtgtc cggccgaccg gacaccgccg ccgcccgacg cagcggtcgg
    17701 aggcgacggg gttggagtcg gacgcagcgg gtaccgcagc cggcatgcgg atcgtgatcg
    17761 tgggtgccag tggcaacgtg ggcacggcgg tgctgcgccg gctgggccgg gagccggggc
    17821 tggacctcgt cggcgtcgcc cggcggctgc ccggcccgga cgccggtgcg ccctacgacg
    17881 gggtgcggtg gcactcctgc gacgtcgggg cgcccggcgc ggtcgaccag ctcaccgcga
    17941 tcttcaccca ggccgatgcg gtggtgcacc tggcctggca gatccaaccc agccacgacc
    18001 agcgcaccct gcaccggacc aacgtcggcg gcagccgcgc ggtgaccgag gccactgtcc
    18061 gggccggcgt gcccgccctg gtgtacgcct cctcggtcgg cgtctacgcc cccggcccga
    18121 aggaccaccc gatcagcgag cggtggccgg cgaccggggt gcccggttcc tcgtacagcc
    18181 gggacaaggc cgaggtcgag gcgatgctgg acaccgtcga ggccgcgcat ccgcagctgc
    18241 gggtggtccg gctgcgcccc gggctgatct tccagcggga cgcgggcacc gagatcaccc
    18301 ggtacttcct cgggccgctg gccccggtgc ggctgctgcg acacgggcgg attccgctcg
    18361 taccggccca ccgtcggctg cggatgcagg cggtgcacgc cgacgacgtg gccgacgcgt
    18421 acgcgcgggc ggtcctcggt gaggcgcgcg gcgcgttcaa cgtcgccgcg gacccggtgc
    18481 tgaccccgga gctggtggcc cggcacttca agggctggac ggtgccggtg gccgccccgg
    18541 tgctgcgtgc cgccgccgcg ctgacctggc ggttccggct ccaaccggtg gacgcgggct
    18601 gggtcgagct ggggctcaac gcgccgctga tgtccagtgc gcgggccgag accgaactcg
    18661 gctggcagcc gcaggtcgac gcggtgaccg cgttgcggga gctgttcgcc gggatggccc
    18721 acggcgcgca caccggcggc ccgccgatgt ccggcgatgc cgacctgccc ggccgcccgg
    18781 ccggcctgct ccggggccgc gcccccggcc agggcgaccc ctactgaccg gcggttcccc
    18841 ggatgccgcc gggggcgggc cgggccgacc gctcgggacg ccacggtggc gccggccggg
    18901 gcgggggccg cttcctcctc cgccggtacg cggcgtcagg cgtgggagag ggcgaacgcg
    18961 gtgaggaagc cgaggacggt gatcaggccg accagcaggt gcgcgtcctc gaacgcctcc
    19021 gggaccatgg tgtcggtgat catcgcgagg atcgcgccgg cggccagcgc ggtgatggtg
    19081 gccagcacct ccggcggcgc accacccagc agggtgtgac cgagcagggc ggcgatcccg
    19141 ctgatcaggg tgatcgccgt ccacagggcg aagacgtagc ggcgggagcg gccggcccga
    19201 cgcatcccgg cggcgctcga cagcccctcc ggcacgttgc tgaggaagac cgcgaccacg
    19261 gtgaccaggc tgaccggccc gccggtcagc aggctcgcgc cgatcaccac cgactcgggt
    19321 acgccgtcca gcagcgcgcc caccgcgatc gccgaccccg acccgggctg ctcctgctcg
    19381 gagggctgct ccccgccgga gcgcttccgg tgccgggcac cccgtcgggc gaggagcacg
    19441 ttcgccccgg tgtacgccag cgccccgccc gtcgccccga tcacggtcgg caacagcccg
    19501 ccctgctcgt gcgcctcggc gatcagctcg aacgacacgg ccgagagcag tacgcccgcg
    19561 ccgaacgcca tgatcgacgc gacgaccatg cggggcaccc ggacgaagaa cccgacggct
    19621 gccccgatca gcagggcgga gccggccaac agcccccacg ccccggcttg ccaccactcc
    19681 ggcattctgg ggaccgtacc cgcccccgga gcgcgtcaac cagccccggc cgtcccgatc
    19741 cggcgacacc ggacggcccg gcggtccggc gcggaccgga cgggtcagaa gtcggcgaag
    19801 aggtagggca gggcgcgcgg gaagatccgc cgcagcgcgg ccgccgcctc cgggccgacg
    19861 tcacccagcc cccggatgtg cacctcggcc gggtcgagca ccccgtacgc cagcgcggac
    19921 agcccggcgg cggtgagcgt cacctccggc accgcagcgc cggaggtcac cgccgaccgg
    19981 ccaccggagg tcagctccaa ccggccggag gcgccgtcga gcaggtgggt gccggcgagc
    20041 cagcggtcgt cgaccagttc cacccggacc cgaccgggcc cggcgggcag cccggcgagg
    20101 gcgtccacgc cgagcaggcg ggccatcggc gccggtgagc cgggccgggt cacccgggcc
    20161 tcgacgtgca cggccagatc ggtcagccac agctcgggca ggtcgtcggc gggcagctgg
    20221 aggctgatcc gctccacctg gtcgacgtgc cgggcgagga actgcaacag cagggcgcgc
    20281 gcgtacgggt cggcggcgag cagatcgtcc ccggccagct ccccgccgtg gtcgtcgatc
    20341 cggtaggtca gcgcgccgac cacgctgccg tcgatcgtcg cggtgatcag ccaacggtcg
    20401 tcccggtccc gcatgccgac gtcccggaac tcggggaaga tcgcgaagcc gtgccgctcc
    20461 cgcaggcacc gctcggtgaa cgagcggtag cgggcgtacc cggggccgat ccgttcccag
    20521 gtcaccgtgc cgggcagctc ggcacccagt agcggagcca ggtcggccgg cgagaaccgg
    20581 gcggtacgcg cccggggcaa ccccacgtag ccgaaccgct cgtagaagct ggcccggaac
    20641 gggtacaacg cgctcaccgg gtgaccaccg tcacgcatct cgtcgaggag ctgacgcagc
    20701 agggcgcgca cgtacccctg gcggcgggcc agcgggtggg tggccacccc ggcgaccccg
    20761 gccatcggca gcaccgcgcc gcgcaggttc tgccgcatcg ggacggcgct ggcggtggcc
    20821 cgcgccacgc caccctcctc gacgaccagc gtccggttgc ccttgttgta cggcaggtag
    20881 cggtggaacg cctccacccg ctccctgctc agcggggacg cctcgaaggc gtacgcctgg
    20941 agcgggaagc tggtggtcag tcgttcctcg gcggccaggc gacggatgag catccgtcca
    21001 tcccaacccg gccggcggcc ggccgcaacc cggttgggcc ggttcagccc tcggtcacgt
    21061 ccgagaccac cacggtgacg ttgtccggtg cgccggcctg gtgggccagc ttgaccaact
    21121 gctcgccgca gtgctgccgg
//
