LOCUS       NZ_LT607410            21227 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Micromonospora purpureochromogenes strain DSM 43821 chromosome I.
ACCESSION   NZ_LT607410
VERSION     NZ_LT607410.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora purpureochromogenes
  ORGANISM  Micromonospora purpureochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091515.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,188
            CDSs (total)                      :: 6,117
            Genes (coding)                    :: 5,981
            CDSs (with protein)               :: 5,981
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 48 of 136
            Pseudo Genes (incomplete)         :: 97 of 136
            Pseudo Genes (internal stop)      :: 4 of 136
            Pseudo Genes (multiple problems)  :: 12 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3777689
            Orig. end                         :: 3798916
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21227
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21227
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11227](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    667..681
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.52"
                     /tool="antismash"
     gene            complement(973..2067)
                     /locus_tag="GA0074696_RS17400"
                     /old_locus_tag="GA0074696_3501"
     CDS             complement(973..2067)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015619421.1"
                     /locus_tag="GA0074696_RS17400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3501"
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="WP_088962074.1"
                     /transl_table=11
                     /translation="MAARLIPRLGSLVDRVLGRQAEASAPAPRRSNPDAVVDCAVYVNG
                     RRETGRPHYADAYARSRRGRNAFVWLGLHDPGAAVMAAVGRTFGLDELVVEQALADGHR
                     PTVQRHDGVTLLVLRTASYVEHAELTATSEVIDTGDVMVFLGDRFVITVRHGASGALTP
                     VRHDIESRPAVLAEGPWAVAYAVAARMVDLYLEVAAHLEKDLERVEESVFAPDRGADIQ
                     HIYQLKREVVEFKRAVLPLQEPVRALVADRAGEPPPGLRRWFLDVESRLSRAVERVAAY
                     DELLNSVLQSRLAQLAVDQNNDMRKIAAWAAIAATQTAVAGVYGMNFTHMPELTWRYGY
                     AGALLLMATAAVVLHRLFRRSGWL"
     gene            complement(2138..2770)
                     /locus_tag="GA0074696_RS17405"
                     /old_locus_tag="GA0074696_3502"
     CDS             complement(2138..2770)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459432.1"
                     /locus_tag="GA0074696_RS17405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3502"
                     /product="class F sortase"
                     /protein_id="WP_088962075.1"
                     /transl_table=11
                     /translation="MALGRWFTRTRASVAAVTVAGAAGLSLITVGLTASPAGPPQPGAG
                     ARGADRSGSPGPVLPRSEPVRIDIPAIGVHADLVSVAGDPNGTLEVPPLDRPTVAGWYR
                     PGVSPGEAGNAVIVGHVDTRDGPAVFFKLGRLRPGDTVRVTRADGRAVTFAVDGVGAYP
                     KRSFPTALVYGPGGPGAGLRLVTCGGRFDERSRDYSDNIVVRATAVA"
     gene            complement(2866..3354)
                     /locus_tag="GA0074696_RS17410"
                     /old_locus_tag="GA0074696_3503"
     CDS             complement(2866..3354)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459435.1"
                     /locus_tag="GA0074696_RS17410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3503"
                     /product="hypothetical protein"
                     /protein_id="WP_088962076.1"
                     /transl_table=11
                     /translation="MKAQSVLVSTALGVGLGTLLLPAAALAQTVVSPATTPVGGTVVLT
                     ATSCNPRAGDAIFRVTGPNRDQNVRSTTAAAGGGLSAELFTAGFTLGTYTVTTTCGDGS
                     SGGSATFTVTPIGAAPAGGGGGDGTTGLLAAGGALAGAAAIGATVMVRRRRRAAAPVA"
     misc_feature    3472..3487
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    complement(3734..3748)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.86"
                     /tool="antismash"
     misc_feature    3735..3748
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.58"
                     /tool="antismash"
     misc_feature    complement(3777..3791)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.25"
                     /tool="antismash"
     misc_feature    complement(4164..4178)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.02"
                     /tool="antismash"
     gene            complement(4250..4768)
                     /locus_tag="GA0074696_RS17415"
                     /old_locus_tag="GA0074696_3504"
     CDS             complement(4250..4768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476891.1"
                     /locus_tag="GA0074696_RS17415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3504"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_088962077.1"
                     /transl_table=11
                     /translation="MPVTNPWLAGPAPAARLDPERLGERILNLLSSQNMCVLATAGPDG
                     PLATPVRYFHLDFAVMFTAAATSPKMRNIAADPRVSVGVFAPLVGQASSRGAQLFGRAR
                     VLHEGDADFDHWWPAVRWQSDHAERGRSLDEPPSGPLVVIEAERIVYTEHWLRRDGYAP
                     RQFWRRAPR"
     gene            complement(4837..5661)
                     /locus_tag="GA0074696_RS17420"
                     /old_locus_tag="GA0074696_3505"
     CDS             complement(4837..5661)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014446552.1"
                     /locus_tag="GA0074696_RS17420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3505"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_088964641.1"
                     /transl_table=11
                     /translation="MTDYRTLNRANWDERAPAHAASPDYAVERFATDPAYLSEVVRFDL
                     PRLGDVTGLRGVHLQCHIGTDTVSLHRLGARMTGLDFSGASLAQARALAERAGAAVDFV
                     EADVYDAPEVLGVGGFDLVYTGVGALCWLPDIRRWAGVVAALLRPGGRLFLREGHPMLW
                     ALDETHPDGLLVVEHPYFERPEPLVWEEPGTYVSTDTTFRHNTTHEWNHGLGEVVTALL
                     DAGLDLTMLQEHDSAPWDALPGRQVKDADGEWRLAERPWRLAQTYTLQARKR"
     gene            5909..7144
                     /locus_tag="GA0074696_RS17425"
                     /old_locus_tag="GA0074696_3507"
     CDS             5909..7144
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF040570.1"
                     /locus_tag="GA0074696_RS17425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3507"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_088962078.1"
                     /transl_table=11
                     /translation="MQLRYNYRVYPTSGQREALARAFGCARVVFNDALRARQEAREQGL
                     PYISDGDLSKRVITEAKTTPQRAWLGEVSAVVLQQALADLHLAYRNFFASLSGKRKGRK
                     VAPPRFRSRKDNRQAIRFTANARFKVLDNGRLRLPKIGDLAVRWSRALPAAPSSVTVVM
                     DAAGRYFASFVVQAADEALPPADAEVGIDLGLTHFAVLSDGTKVAAPRFLRRVARKLRR
                     LQQDLSRKQRGSNNRKKAVVKVAKAHARVADTRRDWQHKLSMQIIRDNQAVYVEDLCVT
                     GLARTRLAKSVHDAGWAGFTAMLQYKAARYGRTFAKIHRFAPTSQTCSVCSRLDGPKPL
                     NIRSWTCPCGAVHDRDVNAAINVLAAGRAESLNACGAQVRPAPMPAPRREAGIRPRVAR
                     CSTRNAEGTPVP"
     gene            7186..7644
                     /locus_tag="GA0074696_RS17430"
                     /old_locus_tag="GA0074696_3508"
     CDS             7186..7644
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0074696_RS17430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0074696_3508"
                     /product="hypothetical protein"
                     /protein_id="WP_231925053.1"
                     /transl_table=11
                     /translation="MGGLLGAVVGDRLVAAIGATWTIRVGLLVEAGLHLALAASTSAWL
                     IGGALFAFGVHGALWNMVSNSLRQRLTPAALQGRVGGTTLFIAAGGNCAGALLGGVIAT
                     TFGLTAPYWVGFVVAVPVSAATWRVFDRATVAAAYADPDDRQPVVRIG"
     gene            complement(7649..8719)
                     /locus_tag="GA0074696_RS17435"
                     /old_locus_tag="GA0074696_3509"
     CDS             complement(7649..8719)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457702.1"
                     /locus_tag="GA0074696_RS17435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3509"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_088962079.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.3e-23, bitscore:
                     80.0, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.8e-32,
                     bitscore: 109.0, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANTPAPLRVGLLGYGLAGQVFHAPLVAATPGLRLDAVVTGNPQR
                     QEQARKDHPDARVLDDADRLWESADSLDLVVVATPNRTHVPMARAAVTAGLAVVVDKPL
                     AATAAEGRALIDEADRRGVPLTVFQNRRWDGDFLTARRLIAEGELGQVLRFESRFERWR
                     PAIKEGWRESAAPGEAGGALYDLGAHLVDQAVQLFGPVRSVYAEVDRRRPEAQVDDDAF
                     VALTHAGGVHSHLWMSAVTAQLGPRMRVLGDRAGWTSYGLDVQEEALRAGARPDAPGWG
                     EVPAERYGRLGVDGDLRPVPTDPGRYQDFYAQVAAALRAGTPMPVDPRDAVATVELIEL
                     AHRSAQRGEVLPVPAR"
     gene            complement(8811..9920)
                     /locus_tag="GA0074696_RS17440"
                     /old_locus_tag="GA0074696_3510"
     CDS             complement(8811..9920)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012308.5"
                     /locus_tag="GA0074696_RS17440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3510"
                     /product="serpin family protein"
                     /protein_id="WP_088962080.1"
                     /transl_table=11
                     /translation="MSSTPANALTANWAALIDDRQTVLSGAGAYPLLALLARHAAGPAR
                     DELSAVAPDATPYDLAASPTTRLALGFWARRELRLNPAWLRAVPASMRGELTGDRAVDQ
                     PVLDRWASTHTDGQIPKMPITVTPDTALVLASALSVLTGWAAPFQEGWCEPRQGPWQGR
                     RLVGLHRYGGDPRALRVADTPAGPVSLLTVAGAADVDVVLALGAPGRPAGAVLPAAIRA
                     LAGGPTLPDTAGPGVTEETVEAFDDRPQLAVHTVAFRVDADHDLLDRAELYGLAAATRR
                     DADNFPGIAPLLYVSQARQTVTAEFSATGFRAAAVTAVAIAPGSAPPRHRARARRVSFD
                     VDRPFGFLAVHRPTGLVLVAGWVTEPTPR"
     gene            10001..11227
                     /locus_tag="GA0074696_RS17445"
                     /old_locus_tag="GA0074696_3511"
     CDS             10001..11227
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018809091.1"
                     /locus_tag="GA0074696_RS17445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3511"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_088962081.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1.6e-75, bitscore:
                     253.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNVDLAVVGGGGAGSLLLAALDRHDLRELRIAVVDRVRKRGQDR
                     TWAFWGTPGTDLEPMLSASWRQVEVTTPAGRRRLDLAPLRYAMLRSAPVYERAAEAERR
                     LGATRVDAAVGALDDDGGSVTVRDADGTALLRARWVLDSRPRPPRRAGRTSWLQHFRGW
                     WLESAGPVFDPDRAVLMDFRTPQPARGVSFGYLLPVSDRYALVEYTEFSPRRLTDAGYD
                     TALRGYADLLGLDLTALTVREVEDGVIPMTDAPFEGRPSPRVVRLGTAGGATRPSTGFT
                     FSAMHRQADDVARALAAGRAPVPRLAYPRRHLWMDAVALRALDRGAVGGPEFFDRLFDR
                     NPAQRVLRFLDGATTPAEDLAVMRSSPLLPMTSAVVGDAVGRLRARLRPGPAPASLGAG
                     PDRAGQAGS"
     gene            complement(11212..11793)
                     /locus_tag="GA0074696_RS17450"
                     /old_locus_tag="GA0074696_3512"
     CDS             complement(11212..11793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015621295.1"
                     /locus_tag="GA0074696_RS17450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3512"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_088962082.1"
                     /transl_table=11
                     /translation="MRRVVVTNNVSLDGVMQAPGRPDEDTRDGFDRGGWAVPYTDPVLG
                     EKMGRGMASTGALLLGRRTYQDFAGFWPHQTDNPFTPVLDRLTKYVASTTLTAPLPGAN
                     SVLLDGDAVAAVAELRRQDGPDIAVLGSGELVRSLAPHGLIDAYVLIIHPLVLGTGRRL
                     FPDGGHPARLTLVESVTTTTGVVVATYEPA"
     gene            12007..12507
                     /gene="rnhA"
                     /locus_tag="GA0074696_RS17455"
                     /old_locus_tag="GA0074696_3513"
     CDS             12007..12507
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rnhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020519604.1"
                     /locus_tag="GA0074696_RS17455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3513"
                     /product="ribonuclease HI"
                     /protein_id="WP_088964642.1"
                     /transl_table=11
                     /translation="MVEAADGRVVEIWTDGACSGNPGPGGWGALLRYGSHERELCGGEA
                     TPTTNNRMELTAAIRALESLTRPVTVRLHTDSTYVRNGITGWLASWKRNGWLTAAKQPV
                     KNADLWQRLEAACARHEVTWLWVKGHNGHPENERADALANKGMTEARAAAPLSAPAGAR
                     AGR"
     gene            complement(12674..12928)
                     /locus_tag="GA0074696_RS17460"
                     /old_locus_tag="GA0074696_3514"
     CDS             complement(12674..12928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016812419.1"
                     /locus_tag="GA0074696_RS17460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3514"
                     /product="hypothetical protein"
                     /protein_id="WP_088962083.1"
                     /transl_table=11
                     /translation="MTDEQRSDRADSDEPDGTPAYEASLRPPGDSLRSTHDTGDDFADL
                     PAEEHLSARETSRAGYDVDAVSGTADPSQEEAVNPPTER"
     gene            complement(12971..13876)
                     /locus_tag="GA0074696_RS17465"
                     /old_locus_tag="GA0074696_3515"
     CDS             complement(12971..13876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459449.1"
                     /locus_tag="GA0074696_RS17465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3515"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_157745998.1"
                     /transl_table=11
                     /translation="MSETPRGGTELRADCARCVGLCCVAPAFAASADFALDKPAGQPCP
                     NLGADSRCGIHPQLRERGFPGCTVFDCFGAGQHVTQVTFGGRDWRDDPATASAMFATFA
                     VVRPLHELLWYLTEALALTPAGTLHDELRAAVDETRGRTAGGADALRDVDVDAYRGRMN
                     PLLVRASELARAGHDGVDRRGAALLGVDLRGADLVGANLRGACLIGTDLRGVRLRLADL
                     TGADLRGADLRGADLSGALFLHQSQLDAARGDRRTVLPPALRHPPHWSGLGITPVGRPR
                     PGGTHAAARPTARHKRDPRR"
     gene            14053..14661
                     /locus_tag="GA0074696_RS17470"
                     /old_locus_tag="GA0074696_3516"
     CDS             14053..14661
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0074696_RS17470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0074696_3516"
                     /product="hypothetical protein"
                     /protein_id="WP_088962085.1"
                     /transl_table=11
                     /translation="MDEGEREQALLTALTTEHFVLQTSRGATVTESVGRATVFLSLLSA
                     SLIGLGFVSSSERLVTPYLGAVLPTLVVTGLLTFARLVQNMVENSLDLQRIQRIRAYYH
                     RNVSTGHDFFADAVSDEDIARAAWREVGARPGWFQLMLTTAAMVGAVNALLVGLGVTLL
                     VGLLGAGSAVAVGVGVVVALAAFAFQLAFISRRSISRVS"
     gene            complement(14713..15132)
                     /locus_tag="GA0074696_RS17475"
                     /old_locus_tag="GA0074696_3517"
     CDS             complement(14713..15132)
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286430.1"
                     /locus_tag="GA0074696_RS17475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3517"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_088962086.1"
                     /transl_table=11
                     /translation="MPFARRAAATAAALAVAVLTAQAALLPQAAQAAPRSGPETPSVLL
                     LDIDRPGTAEDRSAVLVCGPTGGTHPDAAAACRTLARVDGDLSALSADPGPCTFEYAPV
                     TVHAWGFWQDRPVAWSKSYENRCLLLRGTGALFAF"
     misc_feature    15246..15255
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.81"
                     /tool="antismash"
     gene            complement(15442..16251)
                     /locus_tag="GA0074696_RS17480"
                     /old_locus_tag="GA0074696_3518"
     CDS             complement(15442..16251)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-165). E-value: 6.9e-08.
                     Score: 24.5. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS17480_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459455.1"
                     /locus_tag="GA0074696_RS17480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3518"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_088962087.1"
                     /transl_table=11
                     /translation="MPQRYENYPKVAIVTGADSGIGKACAVALAEAGFDIGITWHRDRA
                     GAQRTAGEVGALGRRCEIAELDLTRLPEAATVVDELADRLDGIGVLVNNAGTGASAPFV
                     DTGWEQWREVLAVDLDGPFLCSQRAARRMRAAGRGGRIINITSVHEHAPRVGSAAYCAA
                     KGGLGLLTRVMAQELAADGITVNAVAPGEISTPMTGQEDVDPFTEDRPGVPVGRPGDAR
                     EVAAVVALLASPAAAYVTGASWPVDGGMLLMGPQAGSHLRSDDWRSV"
     aSDomain        complement(15757..16221)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS17480_PKS_KR.1"
                     /evalue="6.90E-08"
                     /label="GA0074696_RS17480_PKS_KR.1"
                     /locus_tag="GA0074696_RS17480"
                     /protein_end="165"
                     /protein_start="10"
                     /score="24.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGADSGIGKACAVALAEAGFDIGITWHRDRAGAQRTAGEVG
                     ALGRRCEIAELDLTRLPEAATVVDELADRLDGIGVLVNNAGTGASAPFVDTGWEQWREV
                     LAVDLDGPFLCSQRAARRMRAAGRGGRIINITSVHEHAPRVGSAAYCAAKG"
     CDS_motif       complement(16075..16215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074696_RS17480_0001"
                     /evalue="7.90E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="GA0074696_RS17480"
                     /protein_end="59"
                     /protein_start="12"
                     /score="5.7"
                     /tool="antismash"
                     /translation="IVTGADSGIGKACAVALAEAGFDIGITWHRDRAGAQRTAGEVGAL
                     GR"
     gene            16328..17746
                     /locus_tag="GA0074696_RS17485"
                     /old_locus_tag="GA0074696_3519"
     CDS             16328..17746
                     /EC_number="6.5.1.8"
                     /GO_function="GO:0008452 - RNA ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012182691.1"
                     /locus_tag="GA0074696_RS17485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3519"
                     /product="RtcB family protein"
                     /protein_id="WP_088962088.1"
                     /transl_table=11
                     /translation="MDLVEESPYRFRIDRHDPMRVPGVVFASRALLPDAGADKSLEQVA
                     NVATLPGIVGASYAMPDVHWGYGFPIGGVAATAVEDGGVVSPGGVGFDISCGVRLLTAD
                     LDRAALRPRLEAVMDGLSESTPRGMGKGAVWHLTDRAELDAVLRGGSRYAVERGFGVQR
                     DLDRCEDYGAVGDANPAQVSERAVERGARQVGSLGSGNHFLEVQAVEEVYDEAVAGAFG
                     LRAGQVCVMIHSGSRGLGHQICTDYVREMEKVMPGHGIHVPDRQLACAPVSSHEGRAYL
                     GAMAAAANYARANRQLLAHAARQVFARVTGCDLDLVYDISHNLAKIETHEVDGKPRPLC
                     VHRKGATRALPPGHPELPDDLRPAGQPVLIPGSMGTGSYVLTGVAGSPAWASTCHGAGR
                     MQSRKQATKAVRGHDPRRELEAQDIAVRGASRRGLAEEMPAAYKDVTAVVAAAEGAGLC
                     RKVARLVPIGVVKG"
     misc_feature    complement(16364..16378)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(17752..18177)
                     /locus_tag="GA0074696_RS17490"
                     /old_locus_tag="GA0074696_3520"
     CDS             complement(17752..18177)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811045.1"
                     /locus_tag="GA0074696_RS17490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3520"
                     /product="archease"
                     /protein_id="WP_088962089.1"
                     /transl_table=11
                     /translation="MIGGMDRGHRAVPHTADVRIEAWAPDREGCLAEAVAALVQTFVDT
                     TGAHPDGETTVELPADRDEDLLVGILDEVIFRLETEGTVPLATEVRPSADGLRVRWHTV
                     GTDAVELVGAVPKAVSLHELRFAGTDSGWQCAVTVDV"
     gene            18237..18569
                     /locus_tag="GA0074696_RS17495"
                     /old_locus_tag="GA0074696_3521"
     CDS             18237..18569
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476725.1"
                     /locus_tag="GA0074696_RS17495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3521"
                     /product="hypothetical protein"
                     /protein_id="WP_088962090.1"
                     /transl_table=11
                     /translation="MIADDADALAVTFHRMMRAVLAAERPGADTLGRTIELARDWGTGP
                     AADARLADALRRLHGEPDEAPATPESARGAAIGTFAANARRSREGEITPAEFHEIMDDD
                     GGPTRG"
     gene            complement(18627..19310)
                     /locus_tag="GA0074696_RS17500"
                     /old_locus_tag="GA0074696_3522"
     CDS             complement(18627..19310)
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-141). E-value:
                     6.2e-09. Score: 27.7. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS17500_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011904675.1"
                     /locus_tag="GA0074696_RS17500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3522"
                     /product="triacylglycerol lipase"
                     /protein_id="WP_088962091.1"
                     /sec_met_domain="PF00561 (E-value: 3.5e-06, bitscore: 25.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTYISRWLFAVGVAVATVAVAPTPAQAAAYTASSNPILFVHGWN
                     SSASTWNTMISRFQADGWPSSRLRAFSYNTSQSNATTAQQVGQEVDKLLASTGATKVDI
                     VTHSMGGLSSRYYLKNLDGGGKVDRWVSLGGPNHGTSSANACYSTACLEMRIGSTFLAN
                     LNSADETPGVPTYGTWRSNCDGVINPVDSTVLSGASNTLAGCVAHTSLQSDATIYGQVR
                     DFVNR"
     aSDomain        complement(18888..19205)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS17500_Abhydrolase_1.
                     1"
                     /evalue="6.20E-09"
                     /label="GA0074696_RS17500_Abhydrolase_1.1"
                     /locus_tag="GA0074696_RS17500"
                     /protein_end="141"
                     /protein_start="35"
                     /score="27.7"
                     /tool="antismash"
                     /translation="NPILFVHGWNSSASTWNTMISRFQADGWPSSRLRAFSYNTSQSNA
                     TTAQQVGQEVDKLLASTGATKVDIVTHSMGGLSSRYYLKNLDGGGKVDRWVSLGGPNHG
                     TS"
     misc_feature    19270..19285
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.42"
                     /tool="antismash"
     misc_feature    19413..19430
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(19416..19431)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    19424..19441
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.11"
                     /tool="antismash"
     misc_feature    complement(19443..19456)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.26"
                     /tool="antismash"
     gene            19522..20127
                     /locus_tag="GA0074696_RS17505"
                     /old_locus_tag="GA0074696_3523"
     CDS             19522..20127
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459457.1"
                     /locus_tag="GA0074696_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3523"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_088962092.1"
                     /transl_table=11
                     /translation="MLITKYTHACVRLERDGRVLVVDPGTWSEPAALVGADAVLVTHEH
                     TDHIDVLPLAGLGVPVFVPEGAELPALPTLPVQRVRAGQRFTAAGFAVTAVGGRHATIH
                     DGQPDCANLGYVVDDEVYHPGDALHLPGQPVRTLLVPAQASWLKLTEAIGFARAVGAAR
                     THPIHDAQVNERGMASVNGWFAETLGDGYRYLAPGETA"
     misc_feature    complement(19526..19540)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            20248..20607
                     /locus_tag="GA0074696_RS17510"
                     /old_locus_tag="GA0074696_3524"
     CDS             20248..20607
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0074696_RS17510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0074696_3524"
                     /product="hypothetical protein"
                     /protein_id="WP_197700736.1"
                     /transl_table=11
                     /translation="MRRGTSAGYVDGRRGPRQHRTRCLDLAAGGQLRGQGVQQRRHGAA
                     AGLHLTVTFAGDLPDAELAAATLRRGVKTQPLSWHAQRPHPPGLVLGYAANTASEIDEG
                     VAAIGGVLRGRPGPA"
     misc_feature    20923..20936
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 ggtctggtcg gccaccctcg acgacggccg cggcgtggtg ctgaaggtcg gcccgccgcc
       61 cgaggtaccg ctgctgcgct acgagcgggg gatggtcgcc gccgaggcgc gctacctgcg
      121 gctcgtcgcc gcgcgggccc cggaggtgcc cgtcccgccg ctgctgcacc acggcagcga
      181 ccccgtcctc ggcgactggc tgctgaccgg cctgctcgcc gggcgtaccc tgcaccagct
      241 cacggtcgac ggcgcgccgg tcgacgcggt ccgcgccggg ctcggggcgg cgctcgccgc
      301 gctgcaccgg gtcgacggcg accggtacgg ctacgacggc ggccgggccg ccggggcgac
      361 ctggcgggag gccttcaccg ccatggtgga cgatctgctc gccgacgcca ccgactgggc
      421 ggtgccgctg cccgtgccgg cgggacggat gcgggaactg gtccaccggc acgccgctgc
      481 cctcgacgcg gtccgccgtc cggcgctgct gcacttcgac ggctgggccg gcaacgtgct
      541 ggccgtcgcc gggccggacg ggatgccgcg gctcaacggt ctggtcgacg gcgagcggca
      601 cctctacggc gatccgttgc tggacctggt ttcaccgctg atcttccgcc gggccgagga
      661 cgagccggac gacgcgttcc tgcgcggcta ccaggcggct ggcggcccgg tgccgctcga
      721 cgaggcgggc gtgcgccgcc ggctcgggct ctaccggctg cacctgtacc tgctgatgac
      781 cgtcgagatg cccagccggg gcatcaccgc cgacaacgac ccgggccgcg tcgcccggct
      841 cgccgagctg ctggaccggg agctggccgc gctcgccgag ccgtgagccg gcccctgatc
      901 cggcccctga tcgggcccgt gagccggccc cgatccggct cgttccgtcc gcgccggatc
      961 gggcggacgg gctcagagcc agccggagcg gcggaagagc cggtgcagga ccaccgcggc
     1021 ggtcgccatc agcagcaggg cgccggcgta gccgtaccgc caggtcagct ccggcatgtg
     1081 cgtgaagttc atgccgtaca cgccggccac ggcggtctgg gtggcggcga tcgcggccca
     1141 cgcggcgatc ttgcgcatgt cgttgttctg gtcgacggcg agctgcgcga gccgggactg
     1201 gagcaccgag ttgagcagct cgtcgtacgc ggcgacccgc tcgaccgcgc ggctcagccg
     1261 gctctcgacg tcgaggaacc agcggcgcag ccccgggggc ggctcgccgg cccggtcggc
     1321 gaccagcgcg cgcaccggct cctgcaacgg cagcaccgcc cgcttgaact ccaccacctc
     1381 ccgcttgagc tggtagatgt gctggatgtc ggcgccccgg tcgggggcga agacgctctc
     1441 ctcgacgcgt tccaggtcct tctccaggtg ggcggcgacc tccaggtaca ggtcgaccat
     1501 ccgggcggcg accgcgtacg ccaccgccca cggtccctcg gccagcaccg ccgggcggct
     1561 ctcgatgtcg tgccggaccg gggtcagggc gccggaggcg ccgtgccgga cggtgatgac
     1621 gaaccggtcg cccaggaaga ccatcacgtc cccggtgtcg atcacctcgg aggtggcggt
     1681 cagctcggcg tgctcgacgt agctggcggt gcgcagcacc agcagggtca ccccgtcgtg
     1741 ccgctgcacg gtgggccggt gcccgtcggc gagcgcctgc tccacgacga gttcgtcgag
     1801 gccgaaggtg cgccccaccg ccgccatcac cgccgcgccc gggtcgtgca gccccaacca
     1861 gacgaaggcg ttgcggccgc ggcgggagcg ggcgtacgcg tcggcgtagt gcgggcggcc
     1921 ggtttcccgg cggccgttga cgtacaccgc gcagtcgacc acggcgtccg gattggaccg
     1981 ccgcggggcc ggcgcggagg cctcggcctg gcggccgagc acccggtcga ccaacgaccc
     2041 cagtcgcgga atgagccgtg ccgccaccgt ccacctccgc cgccctcgat ccgggggccc
     2101 accgtagtac ggcgccgctc ccgccggtgg tggtgggtca ggccacggcg gtggcccgca
     2161 cgacgatgtt gtcggagtag tcgcgggagc gctcgtcgaa gcgtccgccg caggtcacca
     2221 ggcgcagccc cgcgcccggc ccgcccggac cgtagaccag cgcggtggga aagctccgct
     2281 tcgggtacgc gccgacgccg tccaccgcga acgtcacggc ccggccgtcg gcgcgggtga
     2341 cccgtacggt gtcgccgggc cgcagccgcc ccagtttgaa gaagaccgcc ggaccgtcgc
     2401 gggtgtcgac gtggccgacg atcacggcgt tgccggcctc gccggggctg acgcccggcc
     2461 ggtaccagcc ggcgacggtc gggcggtcca gcggcggcac ctccagggtg ccgttcgggt
     2521 cgccggcgac ggacaccagg tcggcgtgga cgccgatggc cgggatgtcg atgcggaccg
     2581 gttccgagcg gggcagcacc ggcccggggg atccgctgcg gtcggcgccg cgcgcgcccg
     2641 ccccgggctg cggcggcccc gccggcgacg cggtgaggcc caccgtgatc aggctgagtc
     2701 cggcggcgcc ggccaccgtc accgccgcca ccgacgcccg ggtacgcgtg aaccacctgc
     2761 cgagggccat cgcctcacct cccgcgacac ggcgatgcgg tcggggtgcc cgtcccggtc
     2821 gcgccggtgc gggcaccccg tcctagggat ggtgtgaggt acgggtcagg cgacgggcgc
     2881 ggccgctcgg cgtcggcggc ggaccatgac ggtcgccccg atcgcggcgg ctccggcgag
     2941 cgcgccgccc gcggccagca ggccggtggt gccgtcaccg ccgccaccac cggccggcgc
     3001 cgcgccgatc ggggtgacgg tgaaggtggc gctgccgccg gagctgccgt caccgcacgt
     3061 ggtggtcacc gtgtaggtgc cgagggtgaa gccggcggtg aagagttccg cgctcagccc
     3121 gccgccggcc gcggcggtgg tcgagcggac gttctggtcc cggttcgggc cggtgacacg
     3181 gaagatcgcg tcgcccgccc tcgggttgca gctggtggcg gtgagtacga ccgtcccgcc
     3241 gaccggtgtg gtggccggtg acacgacggt ctgcgcgagc gcggcggccg ggagcagaag
     3301 cgtgccgagt cccacgccga gcgccgtcga tacgagaact gactgtgcct tcatacgcgt
     3361 cttccctcac ttttcgtccg ctgtctgcgt gggacgtcgt tcgggtggcc aactccgtaa
     3421 caagcaccgg tgtggccaac actaggaggg ttgggcgtcg cgcccgacgt aaatgagaaa
     3481 tcttcgttgc cgtcacgagt tttccctcgc gccggggagg tgcggatatg cccgcacagg
     3541 accgcccaca acgcccggcc ggtcgtacct gctcgcgcca gtcgtcccct tgcggcgaga
     3601 accgcgcttc cgcgctggcc cgtccccttg tgggaagagc tgtccggatc ggccggtctc
     3661 tcggcgggcg gccggcgcgg cgcgggaagc agtcctgcgc ctcctaaccc cccaccccca
     3721 cctcagatgc gcgcagtttc agagaaagag tggccattcc gggcgctgag gccactgatt
     3781 ctcggaaagt acacccggcc gtcgggtcac gacggggtca aggtgtttcc gacgggcgcg
     3841 gccctgttgc gggcgtccag gctcatgttg ctccactgtg gtcgaggggg cgggaggttc
     3901 ggcgcggccg agttcgaggg cggacggtgt gcgcggtcgg gcccggcggc accaaggggc
     3961 ggccagtggc tcgctcgggc agcgcctgcc accggccgct gcgggggggt gcggacgtac
     4021 ctggtggacg agactcgagc ttcccatcgg gtgacactcc ggtgtggatt tccatgccgg
     4081 cgagggtggc tgccgaggtc ccggcatctg tccattccgt cagcctcgac cgggacccag
     4141 catccagcta gcctcctagg atgccctacg ggttgtggcg cagccggata cccgacagtg
     4201 cgccggaggg agatggcggg tcgagccgca cggcccggcg ttgcgggagc taccgaggtg
     4261 cgcgtcgcca gaactggcgc ggcgcgtacc cgtcgcggcg cagccagtgt tccgtgtaga
     4321 cgatccgttc ggcctcgatg acgaccagcg gtccgctcgg tggctcgtcc aacgaccgtc
     4381 cccgctccgc gtggtcggac tgccagcgca ccgccggcca ccagtggtcg aagtcggcgt
     4441 cgccctcgtg cagcacccgg gcccggccga acagttgcgc gccgcggctg ctggcctgcc
     4501 cgacgagcgg tgcgaacacc ccgaccgaca cccgtgggtc ggccgcgatg ttgcgcatct
     4561 tcggcgaggt ggccgcggcg gtgaacatga ccgcgaagtc gaggtggaag tagcggaccg
     4621 gggtggccag cgggccgtcc gggccggcgg tggcgagcac gcacatgttc tgcgacgaca
     4681 gcaggttgag gatccgctcg ccgaggcgtt ccgggtccag gcgggcggcg ggggcggggc
     4741 cggcgagcca ggggttcgtg acgggcatgg tggatcgtcc catgcccgtc ctgggtcctc
     4801 agagccggtc gccgaccgac cccgatgcgg ggcgaatcac cgcttgcgcg cctggagcgt
     4861 gtacgtctgc gccagccgcc acggccgctc ggccagccgc cactcgccgt cggcgtcctt
     4921 gacctgccgg ccgggcagcg cgtcccaggg cgcgctgtcg tgctcctgga gcatggtgag
     4981 gtcgaggccg gcgtcgagca gggcggtgac cacctcgccg aggccgtggt tccactcgtg
     5041 ggtggtgttg tgccggaacg tggtgtcggt gctgacgtag gtgccgggct cctcccagac
     5101 cagcggttcc ggccgctcga agtacgggtg ctccaccacc agcagcccgt ccgggtgggt
     5161 ctcgtccagc gcccacagca tcgggtggcc ctcgcgcagg aagagccggc cgccggggcg
     5221 tagcagcgcg gcgaccacgc ccgcccagcg gcggatgtcg ggcagccagc acagcgcgcc
     5281 gacgccggtg tagaccaggt cgaagccgcc cacgccgagc acctcggggg cgtcgtagac
     5341 gtcggcctcg acgaagtcga cggcggcgcc ggcccgctcg gccagggccc gggcctgggc
     5401 cagcgaggcg ccggagaagt ccagcccggt catccgcgcc ccgagccggt gcagcgagac
     5461 ggtgtcggtg ccgatgtggc actgcaggtg cacgccgcgc aggccggtca cgtcgccgag
     5521 gcggggcagg tcgaagcgga ccacctcgct caggtacgcc gggtcggtgg cgaagcgctc
     5581 caccgcgtag tccggcgacg cggcgtgggc gggggcgcgc tcgtcccagt tggcccggtt
     5641 gagggtgcgg tagtcggtca ccggcgaacc gtcgcacatc ccaccggcgc cgctcaacgg
     5701 ggattcgtcg ccgcccgcgg ggctggtctg cctcgccgtg atggcggagc gactgcatga
     5761 tttcctccag ccgcgccagg tgccggtcgc cacatacgcg gtgccggaac tttgtcgcga
     5821 agtccaagtg ggcgtgcagg cggaaaggca gtgcgtgccg gtgcggacgt tgcattctct
     5881 gtcataggcc gctgcgagac tgtccggtgt gcagcttcgg tacaactatc gcgtctatcc
     5941 gacgtcgggt cagcgggaag cgttggcgcg ggcgttcggg tgcgcgcggg tggtgttcaa
     6001 cgacgcgctg cgcgcacgac aggaagcccg ggagcagggc ctgccctaca tctccgacgg
     6061 ggacctgtcc aagcgggtga ttaccgaggc gaagacgacg ccgcagcggg cgtggttggg
     6121 cgaggtgtcg gcggtggtgt tgcagcaggc cctcgccgat ctgcacctcg cgtaccgcaa
     6181 cttcttcgca tccctgtccg ggaagcggaa gggtcgcaag gtggccccgc cgcggttccg
     6241 gtcgcgcaag gacaaccggc aggccatccg gttcaccgcc aacgcccgat tcaaggtgct
     6301 ggacaacggt cggctgcggc tgccgaagat cggtgatctg gcggtgcggt ggtcgcgggc
     6361 gttgcccgct gcgccgagtt cggtgacggt cgtcatggac gcagcgggcc ggtacttcgc
     6421 ctcgttcgtc gtccaggcgg ccgacgaggc gctgccgccg gccgacgccg aggtgggcat
     6481 cgacctgggt ctgacccact tcgcggtcct gtccgacggc acgaaggtgg cggcgccgcg
     6541 attcctgcgc cgagtcgccc gcaagctgcg tcgactccag caggacctgt cccgcaagca
     6601 gcggggcagc aacaaccgca agaaggccgt cgtcaaggtg gcgaaggcgc acgcccgggt
     6661 ggctgacacc cggcgagact ggcagcacaa gctctcgatg cagatcatcc gcgacaacca
     6721 agcggtgtac gtcgaggacc tgtgtgttac cggccttgcc cggacccgcc tggcgaagtc
     6781 ggtgcacgac gccggctggg ccggcttcac cgcgatgctg cagtacaagg ccgcccggta
     6841 cgggcgcacc ttcgcaaaga tccaccggtt cgcgcccacc tcgcagacgt gctcggtgtg
     6901 cagccggctc gacggaccca aaccgctgaa catccgatcg tggacctgcc catgcggtgc
     6961 ggtccacgac cgggacgtca acgcggccat caacgtgctc gcggcgggac gcgccgagag
     7021 cctaaacgcc tgtggagcgc aggtaagacc ggcacccatg ccggcaccgc gccgagaagc
     7081 aggaatccgc ccgcgcgttg cgcgctgttc cacgcgcaac gcggagggaa cccccgtccc
     7141 ttaggacggg gagaacgtca agggctgctg ttcacctgca tagcggtggg cgggctgctc
     7201 ggcgcggtgg tcggcgaccg gctggtcgcg gcgatcggcg ccacctggac catccgggtc
     7261 gggctgctgg tcgaggcggg cctgcacctg gccctggcgg cgtcgacgag cgcctggctg
     7321 atcggcgggg cgctgttcgc cttcggggtg cacggcgcgc tgtggaacat ggtctcgaac
     7381 tcgctgcgcc agcggctgac cccggcggcg ttgcaggggc gggtcggcgg cacgacgctg
     7441 ttcatcgccg ccggcggcaa ctgcgcgggt gccctgctgg gcggcgtgat cgccacgacg
     7501 ttcggactga ccgcgccgta ctgggtgggg ttcgtggtgg cggtgccggt gtccgcggcc
     7561 acctggcggg tgttcgaccg ggccacggtc gccgccgcgt acgccgaccc ggacgaccgg
     7621 cagccggtcg tccggatcgg ttgagcggtc agcgggccgg gacgggcagc acctcgcccc
     7681 gctgcgcgga gcggtgcgcc agctcgatca gctccaccgt ggcgacggcg tcgcgcgggt
     7741 cgaccggcat cggggtgccg gcccgcagcg ccgccgccac ctgggcgtag aagtcctggt
     7801 agcggcccgg gtcggtgggc accgggcgga ggtcgccgtc gacaccgagc cggccgtacc
     7861 gctcggcggg gacctcgccc cagcccggcg cgtccgggcg ggccccggcg cgcagcgcct
     7921 cctcctgcac gtccaggccg taactggtcc agccggcgcg gtcgccgagg acgcgcattc
     7981 gcggcccgag ctgcgcggtc acggcgctca tccagaggtg ggagtggacg ccgccggcgt
     8041 gggtgagcgc cacgaaggcg tcgtcgtcga cctgcgcctc gggccgccgc cggtccacct
     8101 cggcgtacac gctgcgcacc ggcccgaaca gctgcaccgc ctggtcgacg aggtgggcgc
     8161 cgaggtcgta gagggcgccg ccggcctcgc cgggggccgc gctctcccgc cagccctcct
     8221 tgatggccgg ccgccaccgc tcgaagcggg actcgaagcg gaggacctgg cccagctcac
     8281 cctcggcgat cagccggcgg gcggtcagga agtcgccgtc ccagcggcgg ttctggaaca
     8341 ccgtcagcgg cacgccgcgc cggtcggcct cgtcgatgag ggcgcgaccc tccgccgcgg
     8401 tggcggccag cggcttgtcc accacgacgg ccagcccggc cgtgacggcg gcccgggcca
     8461 tcggcacgtg cgtgcggttc ggcgtcgcca ccacgaccag gtcgaggctg tccgcggact
     8521 cccacagccg gtccgcgtcg tcgaggacgc gggcgtccgg gtggtccttg cgggcctgct
     8581 cctgccgctg cgggttgccg gtgacgacgg cgtccagccg cagcccgggg gtcgcggcga
     8641 ccagcggggc gtggaacacc tggcccgcca gcccgtatcc gagcagtccg acccgcagtg
     8701 gtgccggcgt gttggccatg gtgtcccctc ggtttcccgt ccgtgccctg gtcgttccag
     8761 gtggtgccgg tacgaaccta cgcgccggcc cggaccggtg tgccgcccgg tcagcgggga
     8821 gtcggctcgg tcacccagcc ggcgacgagg accagaccgg tggggcggtg cacggccagg
     8881 aagccgaacg ggcggtcgac gtcgaagctg acccgtcgcg cccgtgcgcg gtgccggggt
     8941 ggcgcggagc cgggtgcgat ggcgacggcg gtgaccgcgg cggcgcggaa gccggtggcg
     9001 ctgaactcgg ccgtgacggt ctgccgggcc tgggagacgt agagcagcgg ggcgatgccg
     9061 gggaagttgt ccgcgtcgcg gcgggtggcg gcggcgagtc cgtacagctc ggcgcggtcg
     9121 agcaggtcgt ggtcggcgtc gacgcggaac gcgacggtgt gcacggccag ttgcggccgg
     9181 tcgtcgaacg cctcgacggt ctcctcggtg acgccgggcc cggcggtgtc gggcagcgtc
     9241 ggcccgccgg cgagggcgcg gatcgcggcc ggcagcacgg cgccggccgg gcgcccgggg
     9301 gcgccgaggg ccagcaccac gtcgacgtct gccgcaccgg cgacggtcag cagactcacc
     9361 ggtccggccg gggtgtcggc cacccgcagc gcccgggggt cgccgccgta ccggtgcaga
     9421 ccgaccagcc gccgaccctg ccagggaccc tgccggggct cgcaccagcc ctcctggaag
     9481 ggcgccgccc agccggtcag caccgacagg gcgctggcca gcaccagcgc cgtgtccggg
     9541 gtgaccgtga tcggcatctt cgggatctgc ccgtcggtgt gggtggacgc ccagcggtcc
     9601 agcacgggct ggtccacggc ccggtcgccg gtcagctcac cccgcatcga cgcggggacc
     9661 gcgcgcagcc aggccgggtt cagtcgcagc tcgcgtcggg cccagaagcc cagcgccaac
     9721 cgggtggtgg gggaggcggc caggtcgtag ggggtggcgt cgggggcgac ggcggacagc
     9781 tcgtcgcggg ccggaccggc cgcgtgccgg gcgagcaggg ccagcagcgg gtacgcgccg
     9841 gcgccggaca ggacggtctg ccggtcgtcg atcagggcgg cccagttggc ggtgagggcg
     9901 ttggcgggcg tgctgctcat gccgtggcac cgtaccgggc gggcggcgcg ccgtgggggc
     9961 tccgcccggc gggggccggg gggtgtgaca gcgtggtcgg gtggacaacg tcgacctggc
    10021 cgtcgtcggc ggtggcggcg ccggttccct gctcctcgcc gcgctggacc ggcacgacct
    10081 gcgtgagctg cggatcgccg tggtcgaccg ggtgcgcaag cgcggccagg accgcacctg
    10141 ggcgttctgg ggtacgcccg gcaccgacct ggagccgatg ctcagcgcga gctggcggca
    10201 ggtggaggtg accacgccgg ccgggcggcg ccggctcgac ctcgccccgc tgcggtacgc
    10261 gatgctgcgc tccgccccgg tctacgagcg ggccgccgag gcggagcggc gcctcggcgc
    10321 cacccgggtc gacgcggcgg tcggcgccct cgacgacgac ggtgggtcgg tgaccgtccg
    10381 ggacgccgac ggcacggcgc tgctgcgggc ccggtgggtg ctggactccc gcccccggcc
    10441 gccccggcgg gcggggcgga cgagctggtt gcagcacttc cggggctggt ggctggagtc
    10501 ggccgggccg gtgttcgacc cggaccgggc ggtgctgatg gacttccgca ccccgcagcc
    10561 ggcgcggggt gtctccttcg gctacctgct gccggtcagc gaccggtacg ccctggtcga
    10621 gtacaccgag ttctccccgc gacggctgac cgacgccggc tacgacaccg cgctgcgcgg
    10681 ctacgccgac ctgctcggcc tggacctgac cgcgctgacc gtgcgggagg tggaggacgg
    10741 ggtgatcccg atgaccgacg ccccgttcga gggccggccg tcgccgaggg tggtgcggct
    10801 gggcaccgcc ggcggggcca cccggccgtc gaccgggttc accttctccg ccatgcaccg
    10861 gcaggccgac gacgtggccc gggcgctggc cgccggccgg gccccggtgc cccggctggc
    10921 gtacccccgt cgacacctgt ggatggacgc cgtcgcgttg cgggcgctgg accgtggggc
    10981 ggtcggcggc ccggagttct tcgaccggct cttcgaccgc aatccggcgc agcgggtgct
    11041 gcgtttcctc gacggcgcca ccaccccggc ggaggacctg gcggtgatgc ggtccagtcc
    11101 gctgctgccg atgacctcgg ccgtggtcgg tgacgccgtc ggccggctgc gcgcccggct
    11161 gcgccccggc ccggcccccg cgtccctcgg cgcgggcccg gaccgggcgg gtcaggccgg
    11221 ctcgtaggtc gccacgacca cccccgtcgt ggtggtgacg ctctcgacca gcgtcagccg
    11281 ggccgggtgc ccgccgtcgg ggaacagccg ccgcccggtg ccgagcacca gcgggtggat
    11341 gatcagcacg tacgcgtcga tcagcccgtg cggggccagc gaccgcacca gctcgccgct
    11401 gccgagcacg gcgatgtccg ggccgtcctg ccgccgcagc tcggcgaccg ccgcgacggc
    11461 gtccccgtcg agcagcaccg agttcgcccc cggcagcggc gcggtcaggg tggtggaggc
    11521 gacgtacttg gtgagccggt cgagcaccgg ggtgaacggg ttgtcggtct ggtgcggcca
    11581 gaagccggcg aagtcctggt acgtgcggcg accgagcagc agcgcgccgg tggacgccat
    11641 gccccggccc atcttctcgc ccagcaccgg gtccgtgtac ggcaccgccc agccgccccg
    11701 gtcgaagccg tcgcgggtgt cctcgtccgg gcgtccgggc gcctgcatca cgccgtccag
    11761 gctgacgttg ttggtcacga cgacgcgtct catgccggtc ctcgcgggtc acggccggcc
    11821 cgacgccggc ccctcacctc ccagacggac ggcggccggc cctttcgaca caccgtcagc
    11881 gggcgtagcc cgtcgacctc gccgagcagc gcggctacct ccgcgcggtg agagagcccc
    11941 cggtggtgcg gcgcgccggg acgcccgcgc ccagcggcgg tgggcggcac cggtaggttc
    12001 ggcgccatgg tggaggcggc ggacggcagg gtcgtggaga tctggaccga cggggcgtgc
    12061 agcggcaacc ccggcccggg cggctggggc gcgctgctgc gctacggcag ccacgagcgg
    12121 gagctgtgcg gcggcgaggc gacgccgacc accaacaacc ggatggagct gaccgcggcc
    12181 atccgggcgc tggagagcct gacccgaccg gtcaccgtgc ggctgcacac cgacagcacc
    12241 tacgtgcgca acggcatcac cgggtggctg gcgtcgtgga agcgcaacgg ctggctgacg
    12301 gcggccaagc agccggtcaa gaacgccgat ctgtggcagc ggctggaggc ggcctgcgcc
    12361 cggcacgagg tgacctggct gtgggtcaag gggcacaacg gccacccgga gaacgagcgg
    12421 gcggacgcgc tggccaacaa ggggatgacc gaggcgcggg cggcggcgcc gctcagcgct
    12481 ccagcaggcg ctcgcgcagg gcggtgacca gggcgtcgtc gacgtcgcgg gcgtagccgc
    12541 gtaccgagcc gtgcacggcg gtcaggtcgg cgggaagagc tcgatgatcc gcgcgggccg
    12601 ctcgcgccgt cccgctacgt cgtcgggccc ggtcggacgc cgccggccgg gcccgatccg
    12661 catcggggcg cggtcaccgc tcggtggggg gattgaccgc ctcctcctgg gaggggtcgg
    12721 ccgtgccgga taccgcgtcc acgtcgtagc cggcgcggct ggtctcccga gccgagaggt
    12781 gctcctcggc gggcaggtcc gcgaagtcgt cgccggtgtc gtgcgtgctg cgcagcgagt
    12841 cgcccggcgg gcgcagcgac gcctcgtacg cgggggtgcc gtccggttcg tcggagtcgg
    12901 cccggtcgga acgctgttca tccgtcatac cgccctacct gcccgtctgg ccggccggca
    12961 aacacgccgg tcagcggcgg ggatcgcgct tgtgccgggc ggtcgggcgg gccgcggcgt
    13021 gggtcccgcc ggggcgggga cggccgaccg gggtgatgcc gagccccgac cagtgcggcg
    13081 ggtggcgcag cgcgggcggc agcacggtgc gccggtcgcc gcgggccgcg tcgagctgcg
    13141 actggtgcag gaacaacgcg ccggacaggt ccgcgccgcg caggtcggcg ccgcgcaggt
    13201 ccgcgcccgt gaggtcggcc agccgcagcc gcacaccccg caggtccgtg ccgatcaggc
    13261 acgcgccgcg caggttcgcc cccaccaggt ccgccccgcg caggtcgacg ccgagcagcg
    13321 ccgcgccccg ccggtcgacg ccgtcgtggc cggcccgggc cagctcgctg gcccgcacca
    13381 gcagcgggtt catccgcccc cggtacgcgt cgacgtccac gtcgcgcagc gcgtcggcgc
    13441 cgccggcggt gcggcctcgg gtctcgtcca cggccgcccg tagctcgtcg tgcagcgtcc
    13501 ccgccggggt cagcgccagc gcctcggtga gataccagag cagctcgtgc agcgggcgca
    13561 ccacggcgaa ggtggcgaac atggccgacg ccgtcgcggg gtcgtcccgc cagtcccgcc
    13621 cgccgaaggt cacctgggtg acgtgctggc cggcgccgaa gcagtcgaac acggtgcagc
    13681 cggggaagcc ccgctcgcgc agttgcgggt ggatgccgca gcgcgagtcg gcgcccaggt
    13741 tcgggcaggg ctggccggcg ggcttgtcca gcgcgaagtc cgccgaggcg gcgaaggccg
    13801 gggcgacgca gcacaacccg acgcaacggg cgcagtcggc gcgcagctcg gtgccgcctc
    13861 ggggtgtttc ggacacgctg accggtctcc cactggttgg ttggtctgcc gcccgggtcg
    13921 cccgggtcgg cgtacctcat tgtccgccag cggggtgccc gggccgcccg ggggagggtc
    13981 cgcggattcg acgccgaccg ggcggcccgc tttcgtatgg tgggcctatc caggacggcc
    14041 gggggtcggg gcatggacga gggcgagcgg gagcaggcac tgctcaccgc gttgaccacc
    14101 gagcacttcg tgctccagac ctcccgcggc gccaccgtca ccgagtcggt ggggcgggcg
    14161 acggtgttcc tgtcgctgct gtcggcgtcg ctgatcggtc tcggcttcgt ctccagcagc
    14221 gagcggctcg tcacgccgta cctcggggcg gtgctgccga cgctggtggt gaccgggctg
    14281 ctgacgttcg cccggctggt gcagaacatg gtggagaact cgctggacct gcaacggatc
    14341 cagcggatcc gggcctacta ccaccgcaac gtctccaccg gccacgactt cttcgccgac
    14401 gcggtgtcgg acgaggacat cgcccgcgcc gcctggcggg aggttggcgc ccggcccggg
    14461 tggttccagc tgatgctcac cacggcggcc atggtcgggg cggtcaacgc cctgctggta
    14521 gggctcggcg tgacgctgct cgtcgggctg ctcggcgccg ggtcggcggt ggccgtcggc
    14581 gtcggggtgg tggtcgcgct ggccgccttc gccttccaac tcgccttcat cagccgccgg
    14641 tccatctcgc gcgtgtcctg acccgggagg cgcgacgccc gttccccagg gacgggcgcc
    14701 gcgccgatcc ggtcagaagg cgaacagggc gccggtgccg cgcagcagca ggcaccggtt
    14761 ctcgtacgac ttcgaccagg ccaccggccg gtcctgccag aacccccagg cgtggaccgt
    14821 gaccggcgcg tactcgaagg tgcaggggcc cgggtccgcc gacagcgcgg acaggtcgcc
    14881 gtcgacgcgg gccagagtgc ggcaggcggc ggccgcgtcg gggtgggtgc cgccggtcgg
    14941 tccgcagacc agcacggccg agcggtcctc ggcggtgccc ggccggtcga tgtcgagcag
    15001 cagcaccgac ggggtctccg ggccggatcg gggtgcggcc tgcgcggcct gggggagcag
    15061 ggccgcctgg gcggtcagca cggcgacggc gagggcggcc gccgtggcgg cggcgcgtcg
    15121 ggcgaagggc atcgtgacgt ccttccggtt gcgggacccc gggtctcggg gccggtggac
    15181 ggcccgtccg cggtgtggcc gggccgtcga gaaccctagg tggacggtgt gaacgcgaag
    15241 cgtcacgatt tgttacaccg cccgccctcc ggagggcatc aggtgtgaca acctgccctg
    15301 gcgcgcgccg ggagggcgcc cgcccgccgc gacatggtct ccggcccgac gcatgagttg
    15361 ccgcgctgtt gccggccacc cgcccacgcg gccgcccggc gtcgtccgcc ccggccggcc
    15421 gcccccggac gcagggatga ctcagaccga gcgccagtcg tccgagcgca ggtgcgagcc
    15481 ggcctgcggg cccatcagca gcatgccgcc gtccaccggc caggacgcgc cggtcacgta
    15541 cgccgcggcg ggggaggcga gcagcgccac caccgcggcg acctcccgcg catcgccggg
    15601 ccggcccacc ggtacgcccg gacggtcctc ggtgaacggg tccacgtcct cctggccggt
    15661 catcggggtg gagatctcgc ccggggccac ggcgttgacg gtgatcccgt cggcggccag
    15721 ctcctgcgcc atcacgcggg tgagcaggcc cagcccgccc ttcgccgcgc agtacgcggc
    15781 cgacccgacc cggggcgcgt gctcgtgcac gctggtgatg ttgatgatcc ggccgccccg
    15841 cccggcggcg cgcatccgcc gggccgcccg ctgtgagcag aggaacgggc cgtccaggtc
    15901 caccgcgagc acctcgcgcc actgctccca gccggtgtcg acgaacgggg cggacgcccc
    15961 ggtgccggcg ttgttcacca gcacgccgat cccgtcgagc cggtcggcca gctcgtccac
    16021 gacggtggcg gcctccggca gcctggtcag gtccagctcg gcgatctcgc agcggcggcc
    16081 cagggcgccg acctctccgg cggtgcgctg cgcgcccgcg cggtcgcggt gccaggtgat
    16141 gccgatgtcg aagccggcct cggcgagggc gacggcgcag gccttgccga tgccggagtc
    16201 cgcgccggtg acgatggcga ccttcgggta gttctcgtat cgctggggca tgctgccagc
    16261 actacccgga tcgggcgagg gggaaccgga ggggtgtagc cggtccgggc cggggtagcc
    16321 gggcggaatg gacctggtcg aggagtcgcc gtaccggttc cgcatcgacc ggcacgatcc
    16381 gatgcgggtg ccgggagtgg tgttcgcgtc ccgggctctg ctcccggacg ccggggcgga
    16441 caagtcgctg gagcaggtgg cgaacgtggc caccctgccc ggcatcgtcg gcgcctctta
    16501 cgccatgccg gacgtgcact ggggctacgg cttcccgatc ggcggggtcg ccgccaccgc
    16561 cgtcgaggac gggggagtgg tctcgcccgg aggggtcggc ttcgacatct cctgcggggt
    16621 acggctgctc accgccgacc tggaccgggc cgcgctgcgc ccgcggctgg aggccgtgat
    16681 ggacggcctg agcgagtcca ccccgcgcgg catgggcaag ggcgccgtgt ggcacctgac
    16741 cgaccgggcc gagctcgacg ccgtgctccg cggcggctcc cggtacgccg tcgagcgcgg
    16801 cttcggcgtc caacgggacc tggaccgctg cgaggactac ggcgcggtgg gcgacgcgaa
    16861 cccggcccag gtgagcgagc gggcggtgga gcgcggcgcc cgccaggtgg gcagcctcgg
    16921 ctccggcaac cacttcctcg aggtgcaggc ggtggaggag gtctacgacg aggccgtggc
    16981 gggggccttc gggctgcgcg ccggccaggt ctgcgtcatg atccactccg gctcgcgcgg
    17041 gctgggccac cagatctgca cggactacgt ccgggagatg gagaaggtga tgcccgggca
    17101 cggcatccac gtgcccgacc ggcagctggc ctgcgcgccg gtctcgtccc acgagggccg
    17161 ggcctacctg ggggcgatgg ccgccgcggc caactacgcc cgggccaacc ggcagctgct
    17221 cgcccacgcc gcccggcagg tcttcgcccg ggtcaccggc tgcgacctcg acctggtgta
    17281 cgacatctcg cacaacctcg ccaagatcga gacgcacgag gtggacggga agccccgccc
    17341 gctctgcgtg caccgcaagg gcgccacccg ggccctcccg ccgggacacc ccgagctgcc
    17401 cgacgacctg cgcccggccg ggcagccggt cctcatcccc ggctcgatgg gcaccggctc
    17461 gtacgtgctc accggcgtgg ccggctcgcc ggcttgggcg tcaacctgcc acggcgctgg
    17521 ccggatgcag agccgcaagc aggccaccaa ggcggtccgc gggcacgacc cgcgccggga
    17581 gctggaggcg caggacatcg cggtgcgggg cgccagccgg cgcgggctgg ccgaggagat
    17641 gccggccgcc tacaaggacg tcaccgccgt ggtggcggcg gccgaggggg ccggcctgtg
    17701 ccggaaggtg gcccggctgg tgccgatcgg cgtggtgaag ggctgagccg gtcagacgtc
    17761 cacggtcacc gcgcactgcc agccggagtc ggtgccggcg aaccgcagct cgtgcagcga
    17821 gaccgccttc ggcaccgcgc cgaccagctc caccgcgtcg gtgccgacgg tgtgccatcg
    17881 cactcgcagg ccgtcggcgc tcggccgcac ctcggtggcc agcggcaccg tgccctcggt
    17941 ctccaaccgg aagatcacct cgtcgaggat ccccaccagc aggtcctcgt cccggtcggc
    18001 cggcagctcg accgtcgtct cgccgtccgg gtgggcgccg gtggtgtcga cgaaggtctg
    18061 caccagcgcg gcgaccgcct cggccaggca gccttcccgg tccggcgccc acgcctcgat
    18121 ccgcacgtcg gcggtgtgcg ggacggcgcg gtgccctcgg tccatgcccc cgatcatgcc
    18181 cccgccacgg ctgtccggcg gccggaactg tcgcaccggg acgctacgtt gctcgcatga
    18241 tcgccgatga tgcggacgcc ctggccgtca cgttccaccg catgatgcgg gccgttctcg
    18301 ccgccgagcg gcccggtgcc gacaccctcg gccgcaccat cgagctggcc cgcgactggg
    18361 gcaccgggcc ggccgccgac gcccggctgg ccgacgcgct gcgccgcttg cacggcgagc
    18421 ccgacgaagc tccggcgacg ccggagtccg cgcggggcgc ggcgatcggc acgttcgccg
    18481 ccaacgcccg gcggtcgcgc gagggggaga tcacgccggc cgagttccac gagatcatgg
    18541 acgacgacgg cgggccgacc cgaggctgac cccgaggggc cgccggcttg cggaggggtc
    18601 tccgcgcacc gccggcccca ccggcgtcat cggttgacga agtcgcgcac ctggccgtag
    18661 atggtggcgt cgctctgcag gctggtgtgg gccacgcagc ccgccagcgt gttgctcgcc
    18721 ccggagagca ccgtgctgtc cacggggttg atcacgccgt cgcagttcga ccgccaggtg
    18781 ccgtacgtcg ggacgccggg ggtctcgtcg gccgagttga ggttggccag gaacgtcgag
    18841 ccgatccgca tctccaggca ggcggtgctg tagcaggcgt tggcggagct ggtgccgtgg
    18901 ttggggccgc cgagggagac ccagcggtcc accttgcccc cgccgtcgag gttcttcagg
    18961 tagtagcggg aggagagccc gcccatcgag tgggtgacga tgtccacctt cgtcgcgccg
    19021 gtgctggcga gcagcttgtc gacctcctgg ccgacctgct gcgcggtggt ggcgttggac
    19081 tggctggtgt tgtaggagaa ggcgcgcagc cggctcgacg gccagccgtc ggcctggaac
    19141 cggctgatca tggtgttcca ggtgctggca ctgctgttcc agccgtgcac gaacaggatc
    19201 ggattgctcg acgcggtgta ggcggcggcc tgtgcggggg tgggtgcgac ggcgacggtg
    19261 gcgaccgcca cgccgaccgc gaacagccac ctgctgatgt acgtcctcat ggtcgtctgt
    19321 ctctctcgga tgcccgcgcg ggaagggggg tgtgcgcgga ccgacgccca actggtggtc
    19381 ggacgtcggt cgacgggggt ctcggtactc cgatgtgtga cagatgttac tgaccggttg
    19441 ccttttgatg tcaatacatc aatctgtgct gctggcggca cggacagcga cgtcgaggag
    19501 ggccgcggta gcgtgcgtcc gatgctgatc acgaagtaca cccacgcctg cgtgcggctg
    19561 gaacgcgacg gtcgcgtgct cgtcgtcgac cccggcacct ggagcgagcc cgctgctctc
    19621 gtgggcgcgg acgcggtcct ggtcacccac gaacacaccg accacatcga cgtgctgccg
    19681 ctggccggcc tcggcgtacc ggtcttcgtg cccgagggcg ccgagctgcc cgccctgccc
    19741 acgctgccgg tccagcgggt acgggccggg cagcggttca ccgccgccgg cttcgcggtc
    19801 accgcggtgg gtggccggca cgccaccatc cacgacggcc agcccgactg cgccaacctc
    19861 gggtacgtcg tggacgacga ggtctaccac ccgggtgacg ccctgcacct gcccgggcag
    19921 ccggtgcgga cgctgctggt gccggcccag gcgtcctggc tgaagctgac cgaggcgatc
    19981 gggttcgccc gtgcggtcgg tgcggcgcgc acccacccga tccacgacgc tcaggtcaac
    20041 gagcggggca tggccagcgt gaacggctgg ttcgccgaga cgctcggcga cggctaccgc
    20101 tacctcgcgc ccggcgagac ggcctgaccc gggcccggcg ccgcgcccgg ctccgccgtc
    20161 cggtggcgcg ccgtcccggt ccgggccgcg gtccgctccc cgcggcgctc cgctgaccga
    20221 tgtcgccgtg gggagcgggc ggccccggtg cgacggggaa cctcagccgg gtacgtcgac
    20281 ggccggcgcg gcccccgtca gcaccgcacc cggtgtctcg acctggcagc cggcggccag
    20341 ctccgcggtc agggtgtcca gcagcgccgg cacggggcgg cggccgggct gcacctgacc
    20401 gtcaccttcg ccggcgacct gcccgacgcg gaactcgccg ccgccacgct gcgccggggg
    20461 gtgaagaccc agccgctgtc ctggcacgcg cagcgcccgc atccgcccgg actggtcctc
    20521 ggctacgcgg cgaacaccgc gagcgagatc gacgagggcg tcgccgccat cgggggggtg
    20581 ctccgcggcc gtccgggtcc cgcgtgacct cagggacgtg gtcgctggcc cggcgtcgag
    20641 gccacttccg gcgagcaggg ccccgatgac ggggcggtcg cggtccggta gagggcggcg
    20701 agcccggccg ccgtctccgc cagcaggtcg cgcagctcgg tcggggcgag gacctccacc
    20761 tgggcgccga gccgcagcag gtcgccgtgg gcgtgggtca gcgactcgat cggcaccacg
    20821 gtggtgaccc atccgtcggc gtcgggggcg cccgcgcccg cctcggccct cgcgaccacc
    20881 accgcactgc cgatgtcccg gagtcgctcc cggccggcgg gggagagccg gatcaacgcc
    20941 tcgtcgcggt gcaggcgggc acggaactcc atgacgtggg tccgccacca ggtcggcagg
    21001 tcgaagccgg ccggccgctc gaaggtctcc ggcagggcgg tcaggtcgag gatctggttg
    21061 acccggtagc tggctggacc gtttcccccg tcggcgacca cgtaccaccg accgcccttg
    21121 agcaccagcc cgtacggcgc cagcaccgtc gtccgctcgc cgcgccagct gcgatagcgc
    21181 acgcgcagcc ggtgctgccg ccaaaccgcg tccgccgtgg acgccag
//
