LOCUS       NZ_LT607410            22658 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Micromonospora purpureochromogenes strain DSM 43821 chromosome I.
ACCESSION   NZ_LT607410
VERSION     NZ_LT607410.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora purpureochromogenes
  ORGANISM  Micromonospora purpureochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091515.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,188
            CDSs (total)                      :: 6,117
            Genes (coding)                    :: 5,981
            CDSs (with protein)               :: 5,981
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 48 of 136
            Pseudo Genes (incomplete)         :: 97 of 136
            Pseudo Genes (internal stop)      :: 4 of 136
            Pseudo Genes (multiple problems)  :: 12 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3529134
            Orig. end                         :: 3551792
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22658
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="10"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22658
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22658
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12658](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12658)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(4..174)
                     /locus_tag="GA0074696_RS16290"
                     /old_locus_tag="GA0074696_3280"
     CDS             complement(4..174)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014643.5"
                     /locus_tag="GA0074696_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3280"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_157745975.1"
                     /transl_table=11
                     /translation="MDNTPQVAVSDARKEIGKLIDAAHYAGQHTILAKNDEPRAVLVPY
                     RWYIEQQNRPA"
     gene            188..>1240
                     /locus_tag="GA0074696_RS31845"
                     /pseudo=""
     CDS             188..>1240
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF040570.1"
                     /locus_tag="GA0074696_RS31845"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="RNA-guided endonuclease InsQ/TnpB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWYVLYVRLRYNYRVYPTPSQQASLARAFGCARVVFNDGLRARQT
                     ARENGEPYLSDAELSKRVTAAKATPERAWLSEVSSVVLQQALADLNVAYRNFFAWISGK
                     RKGRKVAPPRFRSRKDNRQAIRFTANARFRVLDNGRLRLPKIGDLEVRWSRTLPSAPSS
                     VTIIKDAAGRHFASFVVQTRQDETLPPAGAEVGIDLGLTHFAVLSDGTKVAAPKFLRRA
                     ARKLRRLQQDLSRKQRGSQNRKKAVVKVARAHARVADTRRDWQHKLSTAIIRDNQAVYV
                     EDLCVVGLGRTRLAKSVHDAGWASFTAMLEYKAARYGRTFARVDRFFPSTRMCSDCGRI
                     NDKMALDVRAW"
     gene            complement(1628..2065)
                     /locus_tag="GA0074696_RS31850"
     CDS             complement(1628..2065)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021536.5"
                     /locus_tag="GA0074696_RS31850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_331716547.1"
                     /transl_table=11
                     /translation="MPPSAKRKAPNVDSNDFIGMVAKRANTSSARATALTRATLRTLAE
                     RIDGGEARDLATQLPEDLKAYAFASSETGERFGLDVFVQRVSGRAEVEPALAEIGMRAV
                     FDALRETIPPGDYDDVVSQLPAELGQVADPVAPFDGRRSRG"
     gene            2302..4161
                     /locus_tag="GA0074696_RS16305"
                     /old_locus_tag="GA0074696_3282"
     CDS             2302..4161
                     /EC_number="2.2.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1204: transketolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476702.1"
                     /locus_tag="GA0074696_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3282"
                     /product="transketolase"
                     /protein_id="WP_088964612.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.1e-06,
                     bitscore: 25.6, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.2e-07, bitscore:
                     28.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAERTLGEEQLNQLGELAAQLRVDAIRCSTKAASGHPTSSLSAA
                     DLLAVLISRHVRYDWAEPRNRANDHLIFSKGHASPLLYAVFKAVGAISDQELVDTYRQF
                     GSRLQGHPTPALPWVDVATGSLGQGLPVGVGIALAGQYLDQLPYHVWVLCGDSETAEGS
                     VWEALDKAGHYGLRNLTVLVDVNRLGQRGPTELEWDLDTYRRRVEAFGCQAIVVDGHDL
                     AAIDEALGRARQATGPTVVLARTVKGKGVPEIENKPDWHGKPLKPDLAERAIDALGGVR
                     QIRVTGPQPEPAPPTGARTGQLLQLPRYDRGAKVATRNAYGDALRAIGVRPDVVVLDGE
                     VSDSTRADRFTDAYPDRYFEMFISEQQMVAAAVGLQVRGYRPFASTFAAFLSRAYDFVR
                     MAGVSRADIALSGSHAGVEIGADGPSQMGLEDLAAMRAVQGSTVLYPSDAVSCAALVAQ
                     MVDRKGVNYLRTTRGGHPVLYDNDEPFPVGGSKLLRGGDDDRVALIGAGVTVHNCLAAA
                     DELAAAGINARVIDLYSVKPLDRERLLAAVRDTGGRLVVVEDHYPEGGLGSAVLESLAD
                     LAEPIRLTHLAVRGLPTSGTPTELMDQAGIGVSAIVAAARASV"
     gene            4277..4684
                     /locus_tag="GA0074696_RS16310"
                     /old_locus_tag="GA0074696_3283"
     CDS             4277..4684
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734595.1"
                     /locus_tag="GA0074696_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3283"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_231925025.1"
                     /transl_table=11
                     /translation="MNHAEFIQAVASRPGVLPSQAEPVTRATLEALAERISGGQARDLA
                     SQLPEELRVYVSAPHDNPIPFGLAEFFERIQARAAVDLQAATDGARAVLDTLRAAVSEK
                     EYGDFVAQLPKEFWQLTGPAATRLQPGRIGT"
     gene            4780..5448
                     /locus_tag="GA0074696_RS16315"
                     /old_locus_tag="GA0074696_3284"
     CDS             4780..5448
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="GA0074696_RS16315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3284"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_172894306.1"
                     /transl_table=11
                     /translation="MDDVLDETAPGSTRPADVEGRPTVRVVVVGEPGLLRTAVAAVLAA
                     TPGFEVAGQCDPAEGVAEAVAAARPDLALVDLDAVRDASALTGRLHARSPECAVVVLTS
                     RRTARVLRRALGARVRGVIAKDVPPEELIDHLRAIADGQLMIDSLTALAALDAAVNPLS
                     EREREVAAAAARGLRTKEIAARLHLAPGTVRNHVSTLLRKTGGRSRWDAIQRAQDAGWI
                     "
     gene            5561..6187
                     /locus_tag="GA0074696_RS16320"
                     /old_locus_tag="GA0074696_3285"
     CDS             5561..6187
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734299.1"
                     /locus_tag="GA0074696_RS16320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3285"
                     /product="response regulator transcription factor"
                     /protein_id="WP_088961890.1"
                     /transl_table=11
                     /translation="MVRTLLALKGALVRGALARLLDAEDDIDVVGEADTPDELRSALRA
                     ERPDVAVVDGDLVTADQLCDLASDRPASGPDGGPPGRLLVLVQQRRAARLGPVLAEHSR
                     RIGFLSHDVAPGRIVEGVRQLADGQVVLDPDLVVAALAVVDSPLTPREREVLDVAAEGH
                     PVRDIAERLVLSAGTVRNHLSRIMAKTGARTRLEAVRIARESGWI"
     gene            complement(6117..7889)
                     /locus_tag="GA0074696_RS16325"
                     /old_locus_tag="GA0074696_3286"
     CDS             complement(6117..7889)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018348540.1"
                     /locus_tag="GA0074696_RS16325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3286"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088961891.1"
                     /transl_table=11
                     /translation="MSAVGEVTRAALRARRAELCRLAGWSVAEALPAGLAGLLTARAVD
                     DGFLAGRPATGLLWLGLLAAAVLVGAVGTNRAYALLGDVVEPFRDDLLRRVVVGALAGA
                     TGGRGDDAAVARLTHQVEMVRDTYAGLLMVVRGFLFAAGAAVVGLFSLAAPVALLVTVP
                     VLAGLGLFAAALPAMIARQRQYVLADERLGRVAVTAVAGHRDVTVSGARDRTTRWVGGY
                     VDDQARVERRLATMAATRGLTLAVGGWVPVPVVLLAIPWLVRQGLGPGAVLGALVYVVR
                     GVQPALHTLVQGVAAGGLRFAVTLDRLLRADVPVRPPAPATARVPRQTAPALSLRGVTF
                     RYGPHADPVLDGLDLDVPAGDHLVIVGASGIGKSTLAGLMAGVLSPQAGTVRVGGLPVA
                     GATPAELAGRRVLIPQEAYVFTGTVRENLTYLRPDLPDPAITRAATRLGLTGLVDRLGG
                     YDATLRPADLSAGERQQLALLRAWLSPAPLMILDEATCHLDPATEARLEEAFADRPGTL
                     VVIAHRVSSALRARRVLLLDGRVALLDSHRGLLDRSAAYRELVGYGEADLLRSSPTPGR
                     SAPLPAGYAPRSSP"
     gene            complement(7886..9553)
                     /locus_tag="GA0074696_RS16330"
                     /old_locus_tag="GA0074696_3287"
     CDS             complement(7886..9553)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461899.1"
                     /locus_tag="GA0074696_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3287"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088961892.1"
                     /transl_table=11
                     /translation="MTPADRLLLRTVGSAGWWTPVLAVVAVVGVAAELALPATLGRAVD
                     AAVGTAPGASSGHWLAAVVGLIAVLVTTGAVRDYGTGAATARSVAGLRHALARHIFALD
                     PRIAARRPVGDLVGRLVGQVADAGQAAPTVVLAGTVLLPPLGSLVALTLIDPWLGLTFV
                     VGLLLLGVLLRSFVADASAAVAGYQQAQGELAGRMVEALAGARTIAAAGTADLEVARVL
                     TPVAALRAHGARTWTVLAGAATRGAVVNPLLQLAVVAVGGLSLAAGRMTPGELLAALQY
                     AALGAGLGTVVGALNKAVRVRAGCRRAADVLGDPVRRYGTRRLPPGPGELELREVSVRG
                     DDGRLLLDRVDLRIPGGTLLVVVGPSGAGKSLLAAVAGRLRDPDSGEVRLDGVPLTELA
                     PAALHAAVGYGFERPVLVGDTVGEAVGCGADPVPVSRAAAIHDFVERLPERWRTPLAEV
                     AMSGGERQRLGLARALRAGRLLVLDDATSSLDTVTEYRVTRTLTGPGDRRTRIVVSHRV
                     GMAARADLVAWVDGGRVRAVGPHRVLWDDPDYRAVFRA"
     gene            complement(9619..9738)
                     /locus_tag="GA0074696_RS16335"
                     /old_locus_tag="GA0074696_3288"
     CDS             complement(9619..9738)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033212.1"
                     /locus_tag="GA0074696_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3288"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_088961893.1"
                     /transl_table=11
                     /translation="MALLDLQGMELPAAERTGGGSQASLLLCGDSSLSITTCH"
     CDS_motif       complement(9673..9738)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQGMELPAAERTGGGSQ"
                     /locus_tag="GA0074696_RS16335_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9619..9672)
                     /prepeptide="core"
                     /locus_tag="GA0074696_RS16335_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="11.90"
                     /molecular_weight="1612.8"
                     /monoisotopic_mass="1611.8"
                     /core_sequence="ASLLLCGDSSLSITTCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQGMELPAAERTGGGSQ"
                     /leader_location="[9672:9738](-)"
                     /alternative_weights="1630.9"
                     /alternative_weights="1648.9"
                     /alternative_weights="1666.9"
                     /alternative_weights="1684.9"
     gene            complement(9810..9929)
                     /locus_tag="GA0074696_RS16340"
                     /old_locus_tag="GA0074696_3289"
     CDS             complement(9810..9929)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734295.1"
                     /locus_tag="GA0074696_RS16340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3289"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_088961894.1"
                     /transl_table=11
                     /translation="MALLDLQGMELPAAERTGGGSQASLLLCGDSSLSITTCK"
     CDS_motif       complement(9864..9929)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQGMELPAAERTGGGSQ"
                     /locus_tag="GA0074696_RS16340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9810..9863)
                     /prepeptide="core"
                     /locus_tag="GA0074696_RS16340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="11.90"
                     /molecular_weight="1603.9"
                     /monoisotopic_mass="1602.9"
                     /core_sequence="ASLLLCGDSSLSITTCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQGMELPAAERTGGGSQ"
                     /leader_location="[9863:9929](-)"
                     /alternative_weights="1621.9"
                     /alternative_weights="1639.9"
                     /alternative_weights="1657.9"
                     /alternative_weights="1676.0"
     gene            complement(10001..12658)
                     /gene="lanKC"
                     /locus_tag="GA0074696_RS16345"
                     /old_locus_tag="GA0074696_3290"
     CDS             complement(10001..12658)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015621707.1"
                     /locus_tag="GA0074696_RS16345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3290"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_088961895.1"
                     /sec_met_domain="micKC (E-value: 4.5e-244, bitscore: 810.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.2e-12, bitscore: 44.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.1e-10, bitscore:
                     36.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDERYDSYCAVDPLFYDSLASASTVVAGYATDRPVPAGWECEVKD
                     DWLIHGPVDGSLPRQGWKIHVSARLDNAERVLTRVMDYCQPRGIPFKHLRGPRMLLMRN
                     SKYARRAGSGKFITVYPRDDAELELTAKELAALLDGEQGPYILSDLRYGDGPVYLRYGG
                     FAARYCLSPDGQVVPAIEDASGSLVPDRRDPVFHVPEWVTLPDFLAPHLAARNAASTTE
                     LPYRIEKVIHFSNGGGLYEARDTRTGDRVVLKEARPYAGLDATGADAVTRLRREAEVLR
                     QLADVPHLVRVDDEFSFGGHEFLALAFVEGRPLNQLVVERYPLVHLDADRAAYTRWALD
                     VHRQVTEAVDAIHAHGIVYGDLHMFNILVGDDGTATLVDFEVAAPADAAGRPALRNQAF
                     AAPRDRTGLDVDRYALACLRLALFLPLTAMLRLAPEKAAHLADVVAENFPVPRDLLDET
                     VAVIVGGRAEAPDGHAGAPDERAAAPAGTSGAVRIDPDDWPGLRDRLAGAIAASATPHR
                     DDRLFPGDIRQFTGSDGGLNLAHGAAGVLWALRASGASTEREHERWLIDRVREPASGSR
                     LGFYDGLHGIAYVLDRLGHRDEALRLLDLCLDQPWTELGNDLMGGLSGVALNLTHFAGL
                     TGERRYADAARQAVDLVVERLGDVDSVAEVSGGRHPYAGLTRGGAGVALMLLRRYEVDR
                     DPVLLDHAATALRQDLRRCVQRDAGHLEVNEGWRTMPYLAEGSVGIGLVLDQYLRHRPD
                     QQFETAAAAIRRCADFPFYAQSGLFAGRAGIVTYLAGRGEYDAARQQARLLSWHALPYR
                     GLTAFPGDQLLRLSMDLATGTAGVLTALAATRPAEATRLPFLTPLPDARPPSEAGPRPD
                     LRPLPTATPAGSAG"
     misc_feature    12870..12884
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(12906..14489)
                     /locus_tag="GA0074696_RS16350"
                     /old_locus_tag="GA0074696_3291"
     CDS             complement(12906..14489)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013732710.1"
                     /locus_tag="GA0074696_RS16350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3291"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_088961896.1"
                     /transl_table=11
                     /translation="MTTTAPPADVSEVVGTRMSRREVLQALSGLMVGMFVSILASTVVA
                     NALPRIIADLQGSQTVYTWIVTSELLAMTATVPLWGKMADLYSKKLLIQLSLGLFVVGS
                     LIAGFTPNVEVLLVSRVVQGIGAGGMTALATIVMAAMIPPRELGRYAGIFGAVFGVGTI
                     AGPLIGGLLVDTSWLGWRWCFLIGVPFTILSIVLLQRTLHLPVVRRTVKIDWLGAVLIT
                     SGVSTLLIWSSLAGNKFAWASGWTAAMVTGGVVLLALAVLVESRAAEPIVPLDIFRNRT
                     VSLATVASVLVGVAMFGGTVFLSQYFQISLGKSPTVAGLMSLPMIFGLLVSSTIAGQLI
                     TKFGRWKAYLVAGAAVMTVGMLLLSTIDARTSVVVLSIYMAVLGIGVGMLMQNLVLAAQ
                     NDVPAHELGAATSALTFFRSMGGAIGVSALGAVLANRVTSLMTEKLGPAAATGGGSAEV
                     PDLSTLPEPVLRIVQDVYGIATADLFLIGAPIALLALVVVLFIKEKPLHTLSGDERRAQ
                     EEAAAQVPVH"
     gene            complement(14563..15183)
                     /locus_tag="GA0074696_RS16355"
                     /old_locus_tag="GA0074696_3292"
     CDS             complement(14563..15183)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013732709.1"
                     /locus_tag="GA0074696_RS16355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3292"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_088961897.1"
                     /transl_table=11
                     /translation="MTVTEQAATGRRDRKKRLTRAALTAAALRLVAERGLEHVTVEEIS
                     EAADVSSRTFFNYFTCKDDALIADLAVDRDRVVAGLLAAAPQVPALRAVRLALDEAIDT
                     MESERELWRLRLAVIAQNPALLPRLMAGNIETERAMIQAIAARLGVDSDHGHPALVTAV
                     AGAAFRTAMLRWAADTDGRPLRDFVDEAFAAVVAGLPDPSPAS"
     misc_feature    15219..15236
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    15222..15236
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.68"
                     /tool="antismash"
     misc_feature    15224..15238
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.83"
                     /tool="antismash"
     gene            15339..16934
                     /locus_tag="GA0074696_RS16360"
                     /old_locus_tag="GA0074696_3293"
     CDS             15339..16934
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="GA0074696_RS16360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3293"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_197700723.1"
                     /transl_table=11
                     /translation="MTAVDVLVVGAGPTGLAMAAQLAAFGVPVRLVDRAVDRAHESRAL
                     AIQPRTLEVLAGLGVTDELLAGGNPTVRLCLHAHGGVRAVPLFDLGLADTAYPHLLFLS
                     QAETERILGEHLAAAGLGVERGVELVGMDQTGDGVAATLRHADGREEPVSARYVVGCDG
                     AHSTVRHLAGIGFEGGAYPQTFVLADLEADGVADGAAHAFLSGQGPLFLFPLRHPASWR
                     LLVMRPPADAPPPESPVTLDEVQALADTYTGATVRLHDPVWMTNFRLHHRAATRYRAGR
                     VFLAGDAAHIHSPAGAQGMNTGIQDAVNLGWKLAHALRGGADPSLLDTYHAERAPVGRM
                     VLRFTDRAFTAATSTNPVVRFVRGRLAPALIPAVLAPRFVRATAFRTVSQLAIGYRRSP
                     LSTDGPRPPRKGPRAGDRLPDAPLSGADGGTLHRLTAAPRWHLLLCGPPAAWSTGETAG
                     LAQRYPGRLTLHRLTETDSTGGAVPRARALRRLGLAPGASAAYLVRPDGHVGYRSGGTD
                     LAGLTAYLDRWLPS"
     gene            complement(17011..17640)
                     /locus_tag="GA0074696_RS16365"
                     /old_locus_tag="GA0074696_3294"
     CDS             complement(17011..17640)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463452.1"
                     /locus_tag="GA0074696_RS16365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3294"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_088961898.1"
                     /sec_met_domain="HAD_2 (E-value: 3.7e-20, bitscore: 71.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVSSVGAVLLDMDGTLVDSDAAVEGAWRVWAAEYGVDPEAVLAI
                     AHGSPADRTVRRLLPGLDDAAVAAAADWQLALQYDDLSDVTATRGAPALLATLARLGLP
                     WAVVTSADSRLAKARLGAAGIDAPVLVTVEDVTVGKPDPQGYLRAAELLDVPPARCLVV
                     EDAEVGLRAGRAAGAMTAALKGLDGDLRLDDLGQLAELLAGARPRP"
     gene            17695..18912
                     /locus_tag="GA0074696_RS16370"
                     /old_locus_tag="GA0074696_3295"
     CDS             17695..18912
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015624206.1"
                     /locus_tag="GA0074696_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3295"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_088961899.1"
                     /transl_table=11
                     /translation="MASPSRHRAEAARWLTASQVLATLHRRPGITRAAMAAELQLTSGF
                     AAEITARLRELRLLTETPAPARGRGRPTTVLRPHPDGPVVLAVDLRQEDWRHAVATVDG
                     QVHEVRQHSHRTREPATVLAAVRHSVEATRKRYGARLRAVSLAVAGTIHDGHLVQAATL
                     GWRSVDLTTITAGTDLPLLLGNDATLAGVAEARTGAAVAAGTALHLIVGVGIGGTLTIA
                     GVPVTGAHGAAGEYGHLPFGDREQCCPCGARGCWDLDVDGRGLARHLGEPPPADPRRYA
                     GQVLDRSVVDPRARQAVRAVAASLGSGIAGLANIHDPDLITLGGLGPALRHAAADAFDT
                     AYTDGLMALHRARPPSVVDAAHGDEGSLRGAAIVGLDHLTGQSALAEWVRTLATPPGDA
                     APTVSG"
     misc_feature    complement(18956..18971)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     gene            19171..20184
                     /locus_tag="GA0074696_RS16375"
                     /old_locus_tag="GA0074696_3296"
     CDS             19171..20184
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013284309.1"
                     /locus_tag="GA0074696_RS16375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3296"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_088961900.1"
                     /transl_table=11
                     /translation="MSRRTTGPAVEAEGLTKAFGETRALNGIDLQVPAGTVYGLLGPNG
                     AGKTTAVRVLATLLRPDGGTARVFGHDVVADADAVRARVSLTGQYASVDEDLTGTENLV
                     LLGRLLGLKKPAARDRAESMLAAFGLTEAGDRQVKKYSGGMRRRIDIAASILNTPDLLF
                     LDEPTTGLDPRSRNQVWEIIRAVVAHGTTVLLTTQYLDEADHLAGRIAVIDHGRVIAEG
                     TPGELKSSVGSGTVHLRLRDPGQRPEAERVLRAALGVPVQLDADPVALTARVGGGGSDL
                     DATRHAARALADLAGAGIVVDDFSVGQPSLDEVFLALTDHPAATVDEQDNELEAAR"
     gene            20181..21038
                     /locus_tag="GA0074696_RS16380"
                     /old_locus_tag="GA0074696_3297"
     CDS             20181..21038
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013474186.1"
                     /locus_tag="GA0074696_RS16380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_3297"
                     /product="ABC transporter permease"
                     /protein_id="WP_088961901.1"
                     /transl_table=11
                     /translation="MSETATTTTGRAPAVYVPSAEALGTVLAPGARPPRPTALSASLTF
                     GWRAMLKIKHVPEQLFDVTAFPIIMVLMFTYLFGGALADSPRDYLQFFLPGIMVTSVVM
                     ITMYTGVGLNTDIEKGVFDRFRTLPVWRPAALVGMIFGDVLRYVLAALVILGVGLALGF
                     RPGGGLLGVLAGIGLLVVFSFAFSWVWTFFGLILRSEKSVMGVSMMVLFPLTFLSNVFV
                     EPATMPGWLQAFVKVNPVTQLVASVRAAMSGSFNASSVLWTLLWSAGFVVVFGTLTMYR
                     YNRR"
     misc_feature    complement(21236..21251)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.58"
                     /tool="antismash"
     misc_feature    complement(21463..21478)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.88"
                     /tool="antismash"
     misc_feature    22000..22015
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.6"
                     /tool="antismash"
     misc_feature    22283..22298
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.99"
                     /tool="antismash"
ORIGIN
        1 gccttaagcc gggcggttct gctgttcgat gtaccaccgg tacggcacga gaacggcgcg
       61 tggttcgtcg ttcttcgcca ggatggtgtg ctgcccggcg tagtgggccg cgtcgatcag
      121 cttgccgatt tccttgcggg cgtcgctcac cgcgacctgg ggtgtattgt ccatccggcg
      181 atagtacatg tggtacgttt tgtacgtgcg gcttcgttac aactaccgcg tctacccgac
      241 gccgagtcag caggcttcgc tggctcgggc gttcgggtgc gcgcgggtgg tgttcaacga
      301 cgggctgcgc gcacggcaga cggcacggga gaacggcgag ccatacctgt cggacgccga
      361 gctgtccaag cgggtcaccg cagccaaggc gaccccggag cgggcgtggc tttccgaggt
      421 gtcctcggtt gtcctgcaac aggccctcgc ggatctgaac gtggcgtacc gcaacttctt
      481 cgcctggatc tcgggcaagc gcaagggccg caaggtcgcg ccgccacggt tccgttcccg
      541 caaggacaac cggcaggcca tccgcttcac cgccaatgcc cggttcaggg tcctcgacaa
      601 cggccgactc aggttgccga agatcggcga cctggaggtc cgctggtcgc ggacgctgcc
      661 ctccgcaccg tcgagtgtga cgatcatcaa ggatgcggcg ggccggcact tcgcgtcgtt
      721 cgtcgtgcaa accaggcagg acgagacgct gccgccggcc ggggccgagg tgggtatcga
      781 cctggggctg acccacttcg cggtcctctc cgacggcacg aaggtcgccg cgccgaagtt
      841 cctacgccgc gcggcccgca agctgcgccg gttgcagcaa gacctgtccc gcaagcagcg
      901 gggcagccag aaccgcaaga aggccgtcgt caaggtcgcc cgcgcccacg cgcgggtggc
      961 cgacacccgg cgggactggc agcacaagct gtccacggcg atcatccgcg acaatcaagc
     1021 ggtgtacgtc gaggacctgt gcgtcgtcgg tctcggccgg acccggctgg ccaagtccgt
     1081 gcacgacgcc ggttgggcgt cgttcacagc catgttggag tacaaggccg cccggtacgg
     1141 gcgtaccttc gcccgggtgg atcggttctt cccgtccacc cggatgtgct cggactgcgg
     1201 ccggatcaac gacaagatgg cgctcgacgt ccgagcgtgg gactgcccgt gcggcagcac
     1261 ccacgaccgg gacgtcaacg cggccatcaa cgtgctcgcg gcgggacgcg ccgagagcct
     1321 aaacgcctgt ggagcgcagg taagaccggc atccgtgccg gcaccgcgcg aggaagcagg
     1381 aatctgcccg gacgccgcgt gttccacgcg cagcgtggag ggaatctccg tctttcaggg
     1441 cggagagatc gtcaatacca gcacttcggc gccagcatct gttgggactg gtggggctac
     1501 ctcggcgcga ccaactatcc gatcaagggg gcgcgcacgt ggagaccatc atgaacatgg
     1561 tccgccggct ggacggctga gccgccgcgt caccgacggt gccgcgggtg ggtgccggag
     1621 ggcacaccta accgcgactg cgccgcccgt cgaagggtgc caccgggtcg gcgacctgcc
     1681 cgagttccgc cgggagctgg gatacgacgt cgtcgtagtc gccgggtggg atggtctcgc
     1741 ggagggcgtc gaacaccgcc cgcatgccga tctcggccag cgccggctcc acctcggcgc
     1801 gtccgctgac ccgttgcacg aagacgtcga ggccgaaccg ctcgccggtc tcgctggagg
     1861 cgaacgcgta cgccttcagg tcctcgggaa gctgggtggc gaggtcacgg gcctcgcccc
     1921 cgtctatccg ttccgccaag gtccgcagcg tggcccgagt gagggcggtc gctcgcgccg
     1981 atgacgtgtt cgcccgcttc gccaccatgc cgatgaagtc gttgctgtcc acgttcggag
     2041 ccttcctctt ggccgatggc ggcatctacc cgtgcaccac cacggcaaac ggcggggcgc
     2101 gcgcggacac cccgctgccc ggtcgcgagg tgagcttcgg gactggggcc cgcatatcgg
     2161 tggttaccgg atggcgacca ggtttcctgg ctaccgtagg tgcggagccg gtcagcggcg
     2221 agcggcccgg ccgatcggcc ggacggcccg gcgtcgaggg ctggccgaag cagccgatcg
     2281 ctggaggcga cagcggtgac gatggaagca gagcgcactc tcggcgagga gcagctcaac
     2341 cagctgggtg agctcgcggc ccagctgcgg gtggacgcga tccggtgcag caccaaagcc
     2401 gcgtccgggc atccgacgtc gagcctctcc gccgccgacc tgctggcggt gctgatctcg
     2461 cgacacgtgc gctacgactg ggcggagccg cgcaatcgcg ccaacgacca cctgatcttc
     2521 tccaagggcc acgcctcgcc gctgctgtac gcggtcttca aggcggtggg tgcgatcagc
     2581 gaccaggagc tggtcgacac ctaccgccag ttcgggtcgc gtctgcaggg gcatcccacc
     2641 ccggcgttgc cctgggtcga cgtcgccacc ggttcgctcg gtcagggact gccggtcggc
     2701 gtcggtatcg cgctggccgg ccagtatctc gatcagctgc cgtaccacgt gtgggtgctc
     2761 tgcggcgaca gcgagaccgc cgagggctcc gtctgggagg cgctggacaa ggccggccac
     2821 tacgggctgc gcaacctcac cgtgctggtc gacgtcaacc ggctggggca gcgggggccg
     2881 accgagctgg agtgggatct ggacacctac cggcggcggg tcgaggcgtt cggctgccag
     2941 gcgatcgtcg tcgacggtca cgacctggcc gcgatcgacg aggcgctcgg ccgggcccgg
     3001 caggcgaccg gtcccaccgt cgtgctcgcc cgcacggtca agggcaaggg cgtacccgag
     3061 atcgagaaca agccggactg gcacggcaag ccgctgaaac ccgatctcgc cgagcgggcc
     3121 atcgacgctc tgggcggggt acgccagatc cgcgtcaccg ggccgcagcc cgagcccgcc
     3181 ccgcccaccg gcgcccgcac cggtcagctg ctccagttgc cgcggtacga ccggggcgcg
     3241 aaggtcgcca cccgcaacgc gtacggggac gcgctgcgcg cgatcggcgt ccggccggac
     3301 gtggtcgttc tcgacggtga ggtcagcgac tccacccggg ccgacaggtt caccgacgcc
     3361 taccccgacc gctacttcga gatgttcatc tccgagcagc agatggtcgc ggcggcggtc
     3421 gggttgcagg tgcgcgggta ccggcccttc gcctcgacgt tcgcggcgtt cctctcccgc
     3481 gcctacgact tcgtccggat ggccggcgtc tcccgggccg acatcgccct gtccgggtcc
     3541 cacgcgggcg tggagatcgg ggcggacggt ccctcccaga tggggctgga ggacctggcc
     3601 gccatgcgcg ccgtccaggg gtccacggtg ctctatccca gcgacgccgt ctcctgcgcc
     3661 gctctcgtcg cccagatggt cgaccgcaag ggcgtcaact acctgcgcac cacccgaggc
     3721 gggcaccccg tgctctacga caacgacgaa cccttcccgg tgggtggcag caagctgctc
     3781 cgcggcggcg acgacgaccg ggtcgcgctg atcggggccg gggtgaccgt gcacaactgc
     3841 ctggccgccg ccgacgagct ggccgccgcc gggatcaacg cccgggtcat cgacctctac
     3901 tcggtcaagc cgctggaccg ggagcggctg ctcgccgccg tccgggacac cggcggccgg
     3961 ctggtggtcg tcgaggacca ctaccccgag ggcggcctgg ggtcggccgt cctcgaatcg
     4021 ctggccgacc tcgccgagcc gatccggctg acccacctgg cggtacgcgg gctgcccacc
     4081 tccgggacgc cgaccgagct gatggaccag gcggggatcg gggtcagcgc catcgtcgcg
     4141 gcggcgcgcg cctcggtttg agggcgcttc ccggcccgca tcgcggcgct gccacgcggc
     4201 ctccgtgggg gaccgacccc gtttcagcca tccgctcgcg ggtacccgca cggtccggta
     4261 cgagaggggg tccgaggtga accacgcgga gttcatccag gcggtggcgt cacgacctgg
     4321 ggtgttgccg tcgcaggccg agcccgtcac ccgtgccacg ctggaggcgt tggcggaacg
     4381 gatcagtggc ggtcaggccc gggacctcgc ctcgcagctt cccgaggagc tgcgggtcta
     4441 cgtgtccgca ccccacgaca accccatacc gttcgggctc gccgaattct tcgagcggat
     4501 ccaggcacgg gccgcggtgg atctccaggc ggcgaccgac ggtgcgcgtg ccgtgctgga
     4561 cacgctgcgc gcggcggtca gcgagaagga gtacggggac ttcgtcgccc aactgccgaa
     4621 ggagttctgg caactcaccg ggccggcggc cacccggctc caaccgggtc ggatcggcac
     4681 gtaggcgcgg gtgccgcttc aatcgcctgg ggcgaacgtc agtccgccgc gatccgtcaa
     4741 ggacgcatgg ctgggcgggc ccgggggcac agtgacccgg tggacgacgt actggacgag
     4801 acagcgcccg ggtcgacccg gccggcggac gtcgaggggc ggccgacggt ccgggtcgtg
     4861 gtggtcgggg agccggggct gctgcgtacc gccgtggccg cggtcctggc cgccacaccc
     4921 ggtttcgagg tggccggtca gtgcgatccg gccgagggcg tcgcggaggc ggtcgcggcc
     4981 gcgcggcccg acctggccct ggtcgacctc gacgcggtgc gggacgcctc ggccctgacc
     5041 ggacgcctgc acgcccggtc gccggaatgc gcggtggtcg tgctgacctc ccggcgcacc
     5101 gcgcgggtgc ttcggcgggc gctcggtgcc cgggtgcgcg gggtcatcgc caaggacgtg
     5161 ccgccggagg agttgatcga ccacctccgc gcgatcgccg acgggcagtt gatgatcgat
     5221 tcgttgaccg cgctggccgc gctcgacgcg gcggtgaacc cgctcagcga gcgggaacgg
     5281 gaggtcgctg ccgccgccgc ccgggggctg cgcacgaagg agatcgccgc ccggctccac
     5341 ctggccccgg gcaccgtccg gaaccacgtg tcgaccctgt tgcgcaagac gggcgggcgg
     5401 agccggtggg acgcgatcca gcgcgcccag gatgccggct ggatctgacg acacgcggac
     5461 cggggtgtcg cgccagaggt gatttcaata ggattcctga ccgtgcgtca tcgttcgcgc
     5521 acggcacgtc agcaacgggg gttgatgacg gggagtctgc atggtccgca ccctgctcgc
     5581 gctcaagggc gcactcgtcc gcggcgcgct cgcccgactg ctcgacgccg aggacgacat
     5641 cgacgtcgtc ggcgaggcgg acacgccgga cgagctgcga tccgccctgc gagccgagcg
     5701 tcccgacgtc gccgtcgtgg acggcgacct ggtcacggcg gaccagctct gcgacctggc
     5761 gtccgaccgg cccgccagcg gtccggacgg cggcccgccc gggcggctgc tggtcctggt
     5821 ccagcagcgc cgtgccgccc ggctcggtcc cgtgctcgcc gaacacagcc gacggatcgg
     5881 cttcctcagc cacgacgtgg cccccgggcg gatcgtcgag ggcgtccggc agctcgccga
     5941 cggccaggtg gtgctcgacc ccgacctggt ggtcgcggcg ctggcggtcg tcgacagccc
     6001 gctgaccccg cgtgagcggg aggtgctcga cgtggcggcc gagggccacc cggtacggga
     6061 catcgcggag cgcctggtgc tgtccgccgg gacggtccgc aaccacctgt cgcggatcat
     6121 ggcgaagacc ggggcgcgta cccggctgga agcggtgcgg atcgcccggg agtcgggctg
     6181 gatctgagca ggtccgcctc cccgtagccg accagttccc ggtacgcggc cgagcggtcc
     6241 agcaggcccc ggtggctgtc gagcagcgcg acccgcccgt cgagcagcag cacccggcgg
     6301 gcgcgcagcg ccgagctgac ccggtgcgcg atgaccacca gcgtgccggg ccggtcggcg
     6361 aaggcctcct ccagccgcgc ctcggtcgcc gggtccaggt ggcaggtcgc ctcgtcgagg
     6421 atcatcaggg gcgcggggga gagccaggcg cgcagcagcg ccagctgctg acgttccccg
     6481 gcggagaggt ccgccgggcg cagcgtcgcg tcgtagccgc cgagccggtc caccaacccg
     6541 gtcagcccga gccgggtcgc cgcccgggtg atcgccgggt ccggcaggtc gggccgcagg
     6601 tacgtcaggt tctcccgcac cgtgccggtg aagacgtacg cctcctgcgg gatcaggacg
     6661 cgccggccgg ccagctccgc cggcgtggcg ccggccaccg gcagcccgcc gacgcgcacc
     6721 gtgccggcct gcggcgacag caccccggcc atcagcccgg ccagggtgga cttgccgatc
     6781 ccgctcgcgc ccacgatcac caggtggtcc ccggccggca cgtcgaggtc gagtccgtcg
     6841 agcaccgggt cggcgtgcgg gccgtaccgg aaggtcaccc cgcgcaggga cagcgccggc
     6901 gcggtctgcc gcgggacccg ggcggtggct ggcgccgggg ggcgcaccgg gacgtccgcg
     6961 cgcagcagcc ggtcgagggt gacggcgaag cgcagcccgc cggcggccac cccctggacg
     7021 agggtgtgca gggcgggttg cacgccacgc acgacgtaga ccagggcgcc gagcaccgcg
     7081 cccggcccga gcccctgccg gaccagccac gggatggcca ggagcaccac cggcaccggc
     7141 acccagccgc ccacggccag ggtcaagccc cgggtggcgg ccatggtggc caaccgtcgc
     7201 tccacccgcg cctggtcgtc gacgtacccg ccgacccagc gggtggtccg gtcccgcgcg
     7261 ccgctgactg tgacgtcgcg atgaccggcg acggcggtga ccgcgacccg gcccagccgc
     7321 tcgtcggcca gcacgtactg ccgctgccgg gcgatcatcg ccggcagggc cgccgcgaac
     7381 agccccaggc cggccagcac cggcacggtc accagcaacg cgaccggcgc ggccagggag
     7441 aacaggccga cgacggcggc gccggcggcg aacaggaagc cgcgcaccac catcaacagg
     7501 ccggcgtagg tgtcccgcac catctcgacc tggtgggtca gccgggccac cgccgcgtcg
     7561 tcgccgcgac cacccgtcgc gccggccagc gcgccgacga ccacccggcg cagcagatcg
     7621 tcgcggaacg gctccaccac gtctccgagc agcgcgtacg cccggttggt gcccaccgcg
     7681 ccgacgagca cggcggccgc gagcaggccc aaccagagca gcccggtcgc cgggcgcccg
     7741 gccaggaagc cgtcgtcgac ggcccgcgcg gtgagcagcc cggccagccc cgccggcaac
     7801 gcctcggcca ccgaccagcc cgccaaccgg cacagctcgg cgcggcgcgc ccgcagcgcg
     7861 gcccgggtca cctcgccgac cgcgctcacg cccggaacac cgcccggtag tcggggtcgt
     7921 cccagagcac ccggtgcggg ccgaccgcgc ggacccgccc accgtccacc caggccacca
     7981 ggtccgcccg cgcggccatg ccgacccggt ggctgaccac gatccgggta cgccggtcgc
     8041 ccggcccggt cagcgtccgg gtcacccggt actcggtgac ggtgtccagg ctggacgtgg
     8101 cgtcgtcgag gaccagcagc cgtccggcgc gcagcgcgcg ggccagcccg agccgctgcc
     8161 gttcgccgcc cgacatggcg acctcggcca gcggcgtgcg ccagcgttcg ggcagtcgct
     8221 cgacgaagtc gtggatggcc gccgccctgc tcaccggcac cgggtcggcg ccgcacccga
     8281 ccgcctcgcc gaccgtgtca ccgaccagca ccggccgctc gaacccgtag cccaccgccg
     8341 cgtgcagcgc cgccggggcc agctcggtca gcggcacgcc gtccaggcgt acctcgccgg
     8401 agtccgggtc ccgcagtcgt ccggcgacgg cggcgagcag cgacttgccc gccccggacg
     8461 gcccgacgac gacgagcagc gtcccgccgg ggatccgcag gtcgacccgg tcgagcagca
     8521 gacgcccgtc gtcgccccgc acgctcacct cccgcagctc cagctcgccc ggtccgggag
     8581 gcagcctccg ggtgccgtac cggcggaccg ggtcaccgag cacgtcggcc gcgcgccggc
     8641 agccggcccg tacccggacc gccttgttca gggcgccgac cacggtgccc aggccggcgc
     8701 cgagcgccgc gtactgcagg gcggccagca gctcgccggg ggtcatccgc ccggcggcca
     8761 gcgacagccc gccgacggcg acgacggcca gttgcagcaa cgggttgacc accgcgccgc
     8821 gggtcgccgc gcccgccagc acggtccagg tccgcgcgcc gtgcgcgcgc agcgcggcga
     8881 ccggcgtcag cacccgcgcg acctccaggt cggcggtgcc ggcggcggcg atggtccgcg
     8941 ccccggcgag cgcctccacc atccggccgg cgagttcccc ctgcgcctgc tggtagccgg
     9001 cgaccgcggc cgaggcgtcg gcgacgaagc tgcgcagcag cacgccgagc agcaggagcc
     9061 ccaccacgaa ggtgaggccc agccacgggt cgatcagggt gagcgccacc agactgccca
     9121 gcggcggcag cagcaccgtg ccggccagca cgacggtcgg ggcggcctgc ccggcgtcgg
     9181 ccacctggcc caccagccgg cccaccaggt cgcccaccgg acggcgggcg gcgatccgcg
     9241 gatcgagggc gaagatgtgt cgggccagcg cgtgccgcag cccggccacc gaacgggcgg
     9301 tggccgcgcc cgtgccgtag tcccgtaccg cgccggtggt gaccagcacg gcgatcagcc
     9361 cgaccaccgc ggcgagccag tgaccggacg aggcgcccgg cgccgtaccg acggcggcgt
     9421 cgaccgcgcg gccgagggtc gcgggcagtg ccagctcggc ggccacgccg accacggcga
     9481 ccacggccag caccggggtc caccagccgg cggacccgac ggtacgcagc aggagccggt
     9541 cggccggggt catcacacct ctctcacgcc gcggccccgg accggcgtga gccggcccgg
     9601 ggccaggcga actgatcgtc agtggcaggt ggtgatgctc agcgagctgt cgccgcagag
     9661 cagcaggctg gcctggctgc cgccaccggt gcgctcggcg gccggcagtt ccattccctg
     9721 gaggtcgagc agagccatgt cggttcctct ttctctcgtg atgcggatct gggcttggtc
     9781 gggtggtcat cgggtcgacg accgccactt cacttgcagg tggtgatgct cagcgagctg
     9841 tcgccgcaga gcagcaggct ggcctggctg ccgccaccgg tgcgctcggc ggccggcagt
     9901 tccatcccct ggaggtcgag cagagccatg tcgttgcacc tccttccaca tgagtagggt
     9961 ccgtcggccc cggggtgacc cggggagctt cgtgggccgg tcagccggcc gatcccgccg
    10021 gcgtcgcggt cggcagcggc ctcaggtccg gccgcggccc cgcctccgac ggcggcctcg
    10081 cgtccggcag cggcgtcagg aacggcagcc gggtcgcctc cgccggtcgg gtcgccgcga
    10141 gggcggtgag cacgccggcg gtgccggtgg ccaggtccat ggagagccgc agcagctggt
    10201 caccggggaa ggcggtcagc ccccggtacg gcagggcgtg ccagctcaac agccgggcct
    10261 gctgccgcgc cgcgtcgtac tcaccccgcc cggccaggta ggtgacgatc cccgcccgcc
    10321 cggcgaagag gccggactgg gcgtagaacg ggaagtcggc gcagcgccgg atcgccgccg
    10381 ccgcggtctc gaactgctgg tccgggcggt ggcgcaggta ctggtcgagc accagtccga
    10441 tgccgacgct gccctcggcg aggtacggca tggtccgcca accctcgttg acctccaggt
    10501 ggccggcgtc gcgctgcacg caccggcgca ggtcctggcg cagcgcggtg gcggcgtggt
    10561 cgagcagcac cgggtcgcgg tcgacctcgt acctgcgcag cagcatcagc gccaccccgg
    10621 ccccgccccg ggtcagtccc gcgtacgggt gccggccacc gctgacctcg gcgaccgagt
    10681 cgacgtcgcc gagccgctcg acgaccaggt cgaccgcctg ccgagccgcg tcggcgtacc
    10741 gccgctcgcc ggtgagtccg gcgaagtggg tcaggttcag cgcgacgccg gagaggccgc
    10801 ccatcaggtc gttgcccagc tccgtccacg gctggtccag gcagaggtcg agcaaccgca
    10861 gcgcctcgtc gcggtgcccg agccggtcca gcacgtacgc gatgccgtgc agcccgtcgt
    10921 agaagccgag ccggctgccg gaggcgggtt cgcgtacccg gtcgatcagc caccgctcgt
    10981 gttcccgctc ggtggacgcg ccgctcgcgc gcaacgccca cagcaccccg gccgcgccgt
    11041 gggcgaggtt cagcccgccg tcgctgccgg tgaactgccg gatgtcgccg ggaaagagcc
    11101 ggtcgtcgcg gtgcggggtg gcgctggcgg cgatcgcgcc ggcgaggcgg tcgcgcagtc
    11161 ccggccagtc gtccgggtcg atccggacgg caccgctggt gcccgccggc gccgcggccc
    11221 gttcgtccgg tgccccggcg tgaccgtccg gcgcctcggc ccggccgccg acgatcacgg
    11281 cgacggtctc gtcgagcagg tcgcggggca cggggaagtt ctcggccacc acgtcggcca
    11341 ggtgcgccgc cttctccggg gcgagccgca gcatcgccgt cagcggcagg aacagcgcca
    11401 gccgcaggca ggccagggcg taccggtcga cgtccaggcc ggtgcggtcg cgcggggcgg
    11461 cgaaggcctg gttgcgcagc gccggccggc ccgccgcgtc ggcgggcgcg gcgacctcga
    11521 agtcgaccag cgtggcggtc ccgtcgtcgc cgaccaggat gttgaacatg tgcaggtcgc
    11581 cgtagacgat cccgtgggcg tggatggcgt ccaccgcctc ggtcacctgc cggtgcacgt
    11641 ccaacgccca gcgggtgtac gcggcgcggt cggcgtcgag gtggaccagc gggtagcgct
    11701 ccaccaccag ctggttgagc gggcggccct cgacgaacgc cagggccagg aactcgtgcc
    11761 cgccgaagct gaactcgtcg tccacccgca ccaggtgcgg cacgtccgcg agctgccgca
    11821 gcacctcggc ctcccgccgc agccgggtca ccgcgtccgc gccggtggcg tccagtcccg
    11881 cgtacggtcg ggcctccttc aacaccaccc ggtccccggt gcgggtgtcc cgggcctcgt
    11941 acaggccgcc gccgttggag aagtggatca ccttctcgat ccggtacggc agctcggtgg
    12001 tgctcgccgc gttgcgggcg gccaggtgcg gggcgaggaa gtcgggcagg gtgacccact
    12061 ccgggacgtg gaagaccggg tcacggcggt ccggcaccag gctgccgctc gcgtcctcga
    12121 tggccggcac cacctgcccg tctggggaga ggcagtaccg ggcggcgaag ccgccgtagc
    12181 gcaggtagac cggcccgtcg ccgtagcgca ggtcgctgag gatgtacggc ccctgctcgc
    12241 cgtcgagcag cgccgcgagt tccttggcgg tcagctccag ctcggcgtcg tcgcgcgggt
    12301 agacggtgat gaacttgccg ctgccggcac ggcgggcgta cttgctgttg cgcatgagca
    12361 gcatccgcgg cccgcgcagg tgcttgaacg ggatgccgcg tggctggcag tagtccatca
    12421 cccgggtcag cacccgttcg gcgttgtcca gccgggccga cacgtggatc ttccaaccct
    12481 gccgggggag cgagccgtcg accggaccgt ggatcaacca gtcgtccttg acctcgcact
    12541 cccagccggc cggcaccggg cggtccgtcg cgtagccggc gaccacggtg ctcgcactgg
    12601 ccaacgagtc gtagaagagc ggatcgaccg cgcagtacga gtcgtaccgt tcatccatgt
    12661 cgcctgcctc cgccgcctga tcggttgagg tccatcctgc ggacggccga gaggcgtgcg
    12721 aagtgcgatg agtcatcgat cggcggtgag tttcccaccc cgaagtcgtg acaacggcgg
    12781 agtttgaact cgcgaatacc gcgtgaccag tggggaggcc gaccggcgcc ggtgggcggc
    12841 cggaccgccg acggacatgg aacgggggcg ggccgaccgg cccgcccccg tcaccgtggt
    12901 accgctcagt gcaccggcac ctgcgcggcc gcctcctcct gggcgcgtcg ttcgtcgccg
    12961 ctgagggtgt gcagcggctt ttccttgatg aacagcacga cgaccagcgc gagcagcgcg
    13021 atcggcgcgc cgatcaggaa caggtcggcg gtggcgatgc cgtacacgtc ctgcacgatg
    13081 cgcagcaccg gctcgggcag ggtggacagg tcgggcacct ccgcggagcc gccgccggtc
    13141 gccgcggccg ggccgagctt ctcggtcatc agcgaggtca cccggttagc caggacggcg
    13201 ccgagcgcgc tgaccccgat ggccccgccc atgctccgga agaaggtcag cgcggaggtg
    13261 gccgcgccga gctcgtgggc cggcacgtcg ttctgcgcgg cgagcacgag gttctgcatg
    13321 agcatgccga cgccgatgcc cagcaccgcc atgtagatcg acaggacgac gacgctggtg
    13381 cgggcgtcga tggtgctcag gagcagcatc ccgacggtca tcaccgcggc gccggccacc
    13441 aggtaggcct tccaccggcc gaacttcgtg atgagctggc cggcgatcgt cgacgagacg
    13501 agcagaccga agatcatcgg gaggctcatc aggcccgcga cggtcggcga cttgcccagc
    13561 gagatctgga agtactggga caggaagacg gtgccgccga acatcgcgac accgaccagc
    13621 acgctggcga cggtggccag cgagaccgtg cggttgcgga agatgtccag cgggacgatc
    13681 ggctccgccg cccgcgactc gacgagcacc gccagcgcca gcaggaccac accgccggtg
    13741 accatcgcgg ccgtccagcc cgaggcccag gcgaacttgt tgcccgccag cgacgaccag
    13801 atcagcagcg tggagacgcc cgaggtgatc agcaccgcgc ccagccagtc gatcttcacc
    13861 gtgcggcgga cgaccggcag gtgcagggtg cgctgcagca ggacgatgga caggatggtg
    13921 aacggcaccc cgatcaggaa gcaccagcgc cagcccagcc acgacgtgtc gacgagcagg
    13981 ccgccgatca gcggaccggc gatggtgccg acaccgaaga ccgcgccgaa gatgccggcg
    14041 tagcggccca gttcgcgcgg cgggatcatc gccgccatga cgatcgtggc cagcgcggtc
    14101 atgccgcccg caccgatgcc ctgcacgacc cggctgacca gcagcacctc cacgttcggc
    14161 gtgaagcccg cgatcagcga acccaccacg aacagcccca gcgagagctg gatcagcagc
    14221 ttcttgctgt acaggtcggc catcttgccc cacagcggca cggtcgccgt catggcgagc
    14281 agttcgctgg tgacgatcca ggtgtagacg gtctggctgc cctgcagatc ggcgatgatc
    14341 cgcggcagcg cgttcgccac caccgtggag gcgaggatgg acacgaacat gcccaccatc
    14401 aggccggaga gggcctggag aacctcccga cgcgacatgc gcgtgccgac gacctcggac
    14461 acgtcggcgg gcggggcggt tgtggtcatt gatgctccct ttcggggtgg atccggattg
    14521 gctggccccg gaacggacgc gccggggcgg gggactggtg ggtcaggagg cgggcgacgg
    14581 atccggcagg ccggcgacga ccgcggcgaa cgcctcgtcc acgaagtcgc gcagtggccg
    14641 gccgtcggtg tcggcggccc agcgcagcat cgcggtgcgg aaggcggcgc cggccaccgc
    14701 ggtgaccagc gccgggtggc cgtggtcgga atcgacaccg aggcgcgcgg cgatcgcctg
    14761 gatcatggcc cgctcggtct cgatgttgcc ggccatcagg cggggcagca gcgcgggatt
    14821 ctgggcgatg accgccaggc gcagccgcca cagctcccgc tcggactcca tcgtgtcgat
    14881 cgcctcgtcg agggcgagtc ggacggcccg cagcgccggc acctgcggcg cggcggcgag
    14941 cagcccggcc acgacgcggt cgcggtcgac cgccaggtcg gcgatgagcg cgtcgtcctt
    15001 gcaggtgaag tagttgaaga aggtacgtga ggagacgtcc gccgcctcgc tgatctcctc
    15061 caccgtcacg tgctccaggc cgcgttcggc gaccagccgc agcgcggcgg cggtcaacgc
    15121 cgcccgcgtc agccgcttct tgcggtcgcg acgcccggtg gcggcctgtt cggttacggt
    15181 cactccggcg acgctacgag gaaacttgcg gagcctgcaa gtttttattc tgtgaagtga
    15241 tgttcccgac cggcgccgac gcgcccgaga tcggagcgag acgtggccag tctggattcg
    15301 tacgtgatcg ggctccgggg ccgacgggtc gtcctcccgt gaccgccgtc gacgtgctcg
    15361 tggtcggggc ggggcccacc gggctggcca tggcggcgca gctggccgcc ttcggcgtgc
    15421 cggtccgcct ggtcgaccgc gcggtcgacc gggcccacga gtcgcgggcg ttggcgattc
    15481 aaccgcgcac cctggaggtc ctcgccggcc tgggcgtgac ggacgagttg ctggccggcg
    15541 gcaaccccac ggtccggctc tgcctgcacg ctcacggcgg ggtgcgggcg gtgccgctgt
    15601 tcgacctggg cctggcggac acggcgtacc cccatctgct gttcctgtcc caggcggaga
    15661 ccgaacgcat tctgggcgag cacctggcgg cggccgggct cggcgtcgag cggggcgtcg
    15721 agctggtggg gatggaccag accggggacg gcgtggcggc gaccctgcgg cacgccgacg
    15781 gtcgcgagga accggtgtcg gcccggtacg tggtgggctg cgacggcgcg cacagcaccg
    15841 tgcgccacct cgccgggatc ggattcgagg gcggcgcgta cccgcagacg ttcgtcctgg
    15901 ccgacctgga ggccgacggc gtcgccgacg gcgcggcgca cgcgttcctt tccggacagg
    15961 ggccgttgtt cctcttcccg ctgcggcacc cggccagctg gcggctgctg gtgatgcgcc
    16021 cacccgccga cgcgcccccg cccgagtcgc cggtcaccct cgacgaggtg caggcgctcg
    16081 ccgacaccta caccggcgcg acggtgcggc tgcacgaccc ggtctggatg accaacttcc
    16141 ggttgcacca tcgcgccgcc acccgctacc gcgccggacg ggtgttcctg gccggcgacg
    16201 cggcgcacat ccacagcccg gccggcgcgc agggcatgaa caccggcatc caggacgcgg
    16261 tcaacctcgg gtggaaactc gcccacgcgc tgcgcggcgg cgccgatccg agcctgctgg
    16321 acacctacca cgccgagcgg gcgccggtcg gccggatggt gctgcgcttc accgaccggg
    16381 ccttcaccgc ggccacctcc accaacccgg tcgtccgctt cgtccgcggc cgcctcgccc
    16441 ccgcgttgat cccggcggtg ctcgcccccc ggttcgtgcg ggccaccgcc ttccgcacgg
    16501 tgtcgcagct tgccatcggc taccggcgga gcccgctgtc gaccgacggc ccgcgcccgc
    16561 cgcgcaaggg cccccgggcg ggggaccggc tccccgacgc gccgctttcc ggcgccgacg
    16621 gtggcacgct ccaccggctc accgcggcgc cccggtggca cctgctgctc tgcggcccac
    16681 cggccgcctg gtcgacgggc gagacggccg gactggcgca gcggtacccc ggccggctca
    16741 ccctgcaccg gctgaccgaa accgacagca cggggggagc agtcccccgg gcccgcgcgc
    16801 tgcgccggct cggcctggcc cccggcgcca gcgctgcgta cctggtccgc cccgacggcc
    16861 atgtcggcta ccggtcgggc ggcacggacc tggcggggtt gacggcctac ctggaccgct
    16921 ggcttccctc gtgacgcggc ggcgacgccg gtgcgcgctc gaaggcccgg cgcagccgtc
    16981 cgagcggcgc ccgccccacc cgccacgcca ctacggacgc ggccgcgctc cggccagcag
    17041 ctccgccaac tggcccaggt catcgaggcg aaggtcgccg tccaacccct tcagtgcggc
    17101 ggtcatcgcg ccggcggccc gcccggcccg caggccgacc tcggcatcct ccacgaccag
    17161 gcaccgcgcc ggcggcacgt cgagcagctc ggcggcgcgc aggtagccct gcgggtccgg
    17221 ctttcccacc gtgacatcct cgaccgtgac cagcaccggc gcgtcgatcc ccgccgcgcc
    17281 gagccgggcc ttcgccagcc ggctgtcggc gctggtcacc accgcccacg gcagcccgag
    17341 ccgtgccagc gtcgccagca gcgccggcgc accacgggtg gcggtcacgt cggacaggtc
    17401 gtcgtactgc aacgccagct gccagtccgc tgccgcggcc accgcggcgt cgtccaggcc
    17461 cggcagcagt cgccgcaccg tgcggtcggc aggactgccg tgcgcgatcg ccagcaccgc
    17521 ctccgggtcg acgccgtact ctgccgccca cacccgccac gccccctcca ccgcggcgtc
    17581 ggagtccacc agagtgccgt ccatgtccaa cagcaccgca ccgaccgacg acacgtccat
    17641 ggccacctcc cgtaaaatac tcgcacggcg aggataaggt ggtgaggccc gctcatggca
    17701 agcccttccc ggcaccgcgc cgaggcggcg cgctggctca ccgcgtcgca ggtgctggcc
    17761 acgctgcacc ggcgtcccgg catcacccgt gccgccatgg ccgccgagtt gcagctgacc
    17821 agcggtttcg ccgccgagat caccgcccgg ctgcgggagc tgcgcctgct taccgagaca
    17881 cccgcgccgg cgcgcgggcg gggccggccc acgaccgtcc tgcgcccgca tcccgacggg
    17941 ccggtggtac tcgccgtcga cctgcggcag gaggactggc gacacgccgt cgcgaccgtc
    18001 gacgggcagg tgcacgaggt gcggcagcat tcccaccgca cccgtgagcc ggccaccgtg
    18061 ctggccgccg tacggcacag cgtcgaggcg acccggaagc ggtacggcgc gcgccttcgg
    18121 gcggtatcgc tggcggtcgc cggcaccatc catgacggcc acctcgtaca ggccgccacc
    18181 ctcggctggc gctcagtcga cctcaccacc atcaccgccg gcacggacct gccgctgctg
    18241 ctcggcaacg acgccaccct cgccggcgtc gccgaggccc gcaccggcgc cgccgtcgcg
    18301 gccggcaccg ccctgcacct gatcgtgggg gtcggcatcg gcggcacgct caccatcgcc
    18361 ggggtgccgg tgacgggcgc gcacggcgcc gccggcgagt acggccacct gcccttcggc
    18421 gaccgggaac aatgctgccc gtgtggcgcc cgcggttgct gggacctcga cgtcgacggc
    18481 cgtggcctgg cccgccacct cggcgaacct ccacccgccg acccgcggcg ctacgccggg
    18541 caggtcctcg accgttccgt tgtggaccca cgcgcccggc aggcggtccg ggccgtcgcg
    18601 gcctccctcg gcagcggcat cgcgggtctg gccaacatcc acgaccccga cctgatcacg
    18661 ctcggcggac tcggccccgc cctgcggcac gccgccgccg acgccttcga caccgcctac
    18721 accgacggtc tgatggccct gcaccgcgct cgcccaccgt ccgtcgtgga cgccgcacac
    18781 ggggacgagg gttcgctgcg cggcgccgcc atcgtcggcc tcgaccacct caccggccag
    18841 agcgccctcg ccgagtgggt gcgcaccctc gcgacaccac ccggggatgc ggccccgacg
    18901 gtttccggct gatctcccga gtaccaccac accctcccgg cctcgttgaa acagcgaccc
    18961 accaggcgta tgacggagtg gccggccacg gcggtcgatt tcgtgtcgta cggctgccgt
    19021 tcaatctgcc tgcacgccgt cggctggttc cgcaggtctt caacgcggtg ccggtgccgc
    19081 acagcgtccc cggcgggcgg ccccgctggt caggtccgcg cggtgcgacc acaggcgctg
    19141 tccggaatgg gggagagaag ggttgagatc atgagtagac gcaccaccgg cccggccgtc
    19201 gaggctgagg gcctgaccaa agcgttcggg gagacccggg cgctcaacgg catcgatctg
    19261 caggtccccg ccggtacggt ctacggcctg ctcggcccga acggtgccgg caagaccacg
    19321 gcggtacggg tgctggcgac gctgctgcgt cccgacggcg gcacggcgag ggtcttcggt
    19381 cacgacgtgg tcgccgacgc cgacgcggtc cgcgcccggg tcagcctgac cggccagtac
    19441 gcctcggtgg acgaggatct gaccggcacg gagaacctcg tgctgctcgg ccgcctgctg
    19501 ggcctgaaga agccggcggc ccgcgaccgt gccgagagca tgctcgccgc gttcggcctg
    19561 accgaggcgg gcgaccgcca ggtgaagaag tactccggcg gcatgcggcg gcgcatcgac
    19621 atcgcggcga gcatcctgaa cactcccgac ctgctgttcc tggacgagcc gacgaccggg
    19681 ctggaccccc gcagccgcaa ccaggtctgg gagatcatcc gggccgtcgt ggcgcacggc
    19741 acgacggtgc tgctgaccac ccagtacctg gacgaggcgg accatctcgc cggccggatc
    19801 gcggtgatcg accacggccg ggtgatcgcg gagggcaccc cgggtgagct caagtcgtcg
    19861 gtcggctccg gcaccgtcca cctgcggctg cgcgacccgg ggcagcggcc cgaggccgag
    19921 cgggtgctgc gggcggcgct gggcgtgccg gtgcagctcg acgccgaccc ggtcgcgctg
    19981 acggcccggg tcggtggggg cggcagcgac ctcgacgcga cccggcacgc ggcccgcgcg
    20041 ctcgctgacc tggccggcgc cggcatcgtc gtggacgact tctcggtcgg ccagccgagc
    20101 ctggacgagg tcttcctggc cctgacggac catcccgccg ccacggtgga cgagcaggac
    20161 aacgagttgg aggcagcccg atgagcgaga ccgccaccac cacgaccggg cgcgccccgg
    20221 ccgtctacgt accgtccgcc gaggcgctgg gaaccgtgct cgcgccgggc gcgcgaccgc
    20281 cccggccgac ggcgctgtcg gcgtcgctca cgttcggctg gcgcgccatg ttgaagatca
    20341 agcacgtgcc ggagcagttg ttcgacgtga cggcgttccc gatcatcatg gtgctgatgt
    20401 tcacctacct gttcggcggc gccctcgccg acagcccgcg ggactacctg cagttcttcc
    20461 tgcccgggat catggtgacc agcgtcgtga tgatcaccat gtacaccggc gtcggcctca
    20521 acaccgacat cgagaagggt gtcttcgacc gcttccgtac gctgcccgtc tggcggccgg
    20581 cggcgctggt cggcatgatc ttcggcgacg tgctgcgcta cgtcctggcg gccctggtca
    20641 tcctcggtgt ggggctggcg ctggggttcc ggcccggcgg cgggttgctc ggggtgctgg
    20701 ccgggatcgg cctgctggtg gtcttctcgt tcgcgttctc ctgggtgtgg acgttcttcg
    20761 gcctgatcct gcgcagcgag aagtccgtga tgggagtcag catgatggtg ctgttcccgc
    20821 tgacgttcct gagcaacgtc ttcgtcgagc cggccacgat gcccggctgg ctccaggcgt
    20881 tcgtcaaggt caacccggtc acgcagctgg tggcctcggt gcgggcggcg atgtcggggt
    20941 ctttcaacgc gtcgagcgtg ctgtggacgc tgctgtggag cgccgggttc gtcgtggtct
    21001 tcggcaccct gacgatgtac cggtacaacc gccgctgatc ctgacgcgac gacgggtgcc
    21061 gcgatcccag gccgaaccag ccgagcgcga ccgggcgacc gcgctacaga ccgacatcgg
    21121 gcccagttcg gcgagccgcg gaccaggctg gtcaatcagg tcctgtgccg ggcggcgcgg
    21181 atactcggcg cacgggcggt cagttccgtc cgggcggttg gttagcatgc ccggcgatga
    21241 tgactatctt tcgctctctg cggctacgcc gcgccgcccg tcgacacttc ggctggcaga
    21301 agctgcgggc tacgcagctg cgcgcgatgc gcgccctgct ggcgggccgt gacgcgctgg
    21361 tggtactgcc caccgggggc gggaagtctg cggtgtacca ggttcccgcc acgctgctgc
    21421 gcggccccac ggtggtgatc tcaccgctgc tggcacttca gcaggaccag atcggcaacc
    21481 tcaacgagcg gggtgatccg gcgttgcggg cggttcggat cagctccgcg gagagcccga
    21541 gcaagcaggc ggcagcgctg gcggagctgc gctcgggtgc cgcgaggttc ctgttcatca
    21601 cgccggagca gctcagttcg ccgcagcggc tggccgaggt ccgcgcgctg cgtccggccc
    21661 tggtggcggt tgacgaggcg cactgcatct cgtcctgggg ccacgacttc cgccctgact
    21721 acctggctct cggccacctc attcgcgacc tgggccgccc accggtcgtg gcgctgacgg
    21781 ccacggcatc gccgccggtg cgcgacgaca tcacggtgcg gctcggcatg cgcaagccgc
    21841 ggctggtgct gtccggattg gaccgtccga accttgtggt ggcagcaatg cactgcccca
    21901 gtgaggacta ccgctggcgc aggttgctca ccctgctcaa ggaggctgac cggcccggca
    21961 tcgtctacgt gccgacccgg cgggccgccg aggacctcgc cgaacggctg tccgacgcgg
    22021 gttttcccgc gcaggcctac cacggcggca tggcggccgg gctgcgccac cgccgtcacg
    22081 aggacttcct cgccgaccgg gtgccgatca tggtcgcgac gtcggcgttc ggcatgggca
    22141 tcgacaagcc gaacatccgc tgggtggcac atgtggcgct gcccgactcg ccggacagct
    22201 atctgcagga gatcggccgg gcagggcgcg acggtgaacc ggcccgggcg ttgctgctct
    22261 accgagccga ggacgtcgcc ctgcaacgtt tctttcacgg cggcgcgcct gaactggaag
    22321 agctgcgaac ggtcgccgcc gtcctgcaca acggcccgtc gacgcgcacc gcgctggcaa
    22381 agaccaccgg cctgggccag cgcaaggtcg ccggtcacct gagtctgctc gagcaggtgg
    22441 gtgcggtggc gacggggccc cggggcgagc tcacggttgc tccgtacgcg cccctgcccg
    22501 atcaggcggc tcgggaggcg ctggccgagt acgcccgcta tcaggccggg cagcgttccc
    22561 gcaccgacat gatgcgccgc ttcgccgaga gccggggctg ccggatgcag tcgctgctgg
    22621 gctacttcgg agagcagttg agccgtccgt gcgggcac
//
