LOCUS       NZ_LT607410            20942 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Micromonospora purpureochromogenes strain DSM 43821 chromosome I.
ACCESSION   NZ_LT607410
VERSION     NZ_LT607410.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora purpureochromogenes
  ORGANISM  Micromonospora purpureochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091515.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,188
            CDSs (total)                      :: 6,117
            Genes (coding)                    :: 5,981
            CDSs (with protein)               :: 5,981
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 48 of 136
            Pseudo Genes (incomplete)         :: 97 of 136
            Pseudo Genes (internal stop)      :: 4 of 136
            Pseudo Genes (multiple problems)  :: 12 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2522558
            Orig. end                         :: 2543500
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20942
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20942
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20942
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10942](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10942)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    280..291
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            390..1388
                     /locus_tag="GA0074696_RS11810"
                     /old_locus_tag="GA0074696_2375"
     CDS             390..1388
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (20-330). E-value: 6.5e-22.
                     Score: 70.0. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS11810_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462967.1"
                     /locus_tag="GA0074696_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2375"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_088961147.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-21, bitscore:
                     75.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTNREIHLASRPQGWPTADNFRLVETEVPTPGPGQIVVRNQFMS
                     VDPYMRGRMNDVKSYVPPFQLGAPLDGGAVGEVVASEADGVKVGDTVLHGLGWREYALL
                     DAKAARPVDPTIAPVSAYLSVLGMTGLTAYAGLLDVAGMKPGESVFVSAAAGSVGSLVG
                     QIAKLKGAGHVVGSAGSPAKVERLKALGFDAAFDYHDGPVRDSLKAAAPNGIDVYFDNV
                     GGDHLEAAISAMNLHGRAAICGMIAQYNDTEPPAAPRNLAMVIGKRLTLRGFLVNDHGN
                     LREQFVRDVSGWLRDGKLSYDETIVDGIENAPAAFLGLLRGENLGKMLVRV"
     aSDomain        450..1379
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS11810_PKS_ER.1"
                     /evalue="6.50E-22"
                     /label="GA0074696_RS11810_PKS_ER.1"
                     /locus_tag="GA0074696_RS11810"
                     /protein_end="330"
                     /protein_start="20"
                     /score="70.0"
                     /tool="antismash"
                     /translation="NFRLVETEVPTPGPGQIVVRNQFMSVDPYMRGRMNDVKSYVPPFQ
                     LGAPLDGGAVGEVVASEADGVKVGDTVLHGLGWREYALLDAKAARPVDPTIAPVSAYLS
                     VLGMTGLTAYAGLLDVAGMKPGESVFVSAAAGSVGSLVGQIAKLKGAGHVVGSAGSPAK
                     VERLKALGFDAAFDYHDGPVRDSLKAAAPNGIDVYFDNVGGDHLEAAISAMNLHGRAAI
                     CGMIAQYNDTEPPAAPRNLAMVIGKRLTLRGFLVNDHGNLREQFVRDVSGWLRDGKLSY
                     DETIVDGIENAPAAFLGLLRGENLGKMLV"
     CDS_motif       825..866
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074696_RS11810_0001"
                     /evalue="6.70E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="GA0074696_RS11810"
                     /protein_end="159"
                     /protein_start="145"
                     /score="9.3"
                     /tool="antismash"
                     /translation="GESVFVSAAAGSVG"
     misc_feature    1447..1465
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.67"
                     /tool="antismash"
     gene            1465..2232
                     /gene="hisF"
                     /locus_tag="GA0074696_RS11815"
                     /old_locus_tag="GA0074696_2376"
     CDS             1465..2232
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="GA0074696_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2376"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_088961148.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPAGTTPSGFEVTTHGGRRGTGLDAVEWA
                     RRGAELGAGEILLNSMDADGTKAGFDLALIQAVRAVVDVPVVASGGAGAVAHFPPAIGA
                     GADAVLAASVFHFGELTVGEVKDALKAAGHPVR"
     gene            complement(2531..2989)
                     /locus_tag="GA0074696_RS11820"
                     /old_locus_tag="GA0074696_2377"
     CDS             complement(2531..2989)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785229.1"
                     /locus_tag="GA0074696_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2377"
                     /product="hypothetical protein"
                     /protein_id="WP_088961149.1"
                     /transl_table=11
                     /translation="MGESGWRWTDAWIFVSLVIASGAGRHRRAADTRRPEGVRLTDVLS
                     TAEHLNQAIPEREDVEAAVRRLAGAGLVSVSDGWFRITPDGERLWRTRPSAGVGTTVDT
                     VQGVLVRRHTPGSAEWHLPEEDHAAAVQEYIVRSIPAPRRSPEGRTGR"
     gene            complement(3047..3700)
                     /locus_tag="GA0074696_RS11825"
                     /old_locus_tag="GA0074696_2378"
     CDS             complement(3047..3700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072133.1"
                     /locus_tag="GA0074696_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2378"
                     /product="YitT family protein"
                     /protein_id="WP_088961150.1"
                     /transl_table=11
                     /translation="MAAIGNLRHRPVRRLTQLYVGLVLYGVSMALMIRSGLGLNPWDVF
                     HQGLSRQTGISVGTASILVGAVVLLLWIPLRQRPGLGTVSNVVVIGLAVDAAVALLPAD
                     LPLPARIGLLVTGIVANGVATGLYLGADLGPGPRDGLMTGLVARRPGSSVRLIRTGIEV
                     TVLALGWLLGGTAGIGTVAYALAIGPLAQLFTPLFTVPPRSTPDTPVVTLAELR"
     gene            3759..5216
                     /locus_tag="GA0074696_RS11830"
                     /old_locus_tag="GA0074696_2379"
     CDS             3759..5216
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (113-463). E-value:
                     7.8e-30. Score: 96.1. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS11830_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="GA0074696_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2379"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_088964510.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-28, bitscore:
                     95.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGAQLARLLGQWHALPGRRRSPDYAALAAAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRQLRETGHLASRRGAGSWTMLPGTHRVASTGL
                     WTPLDDRDMIDLGVAALAAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREAVARSY
                     TARGLPTSAEQIMVTSGTQHALDLVLRLALAPGGSVLVESPTYPNALAALSARRARITT
                     HGLAVDGAGWDADLLLGSIRQVRPKLAYLIPDFQNPTGHLMSAELRERVVAVAHTAGTD
                     LVVDESFVDLPLDGTELPPPAATFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRL
                     AAARVGVDMASPVLDQLVAVHLLADAPTIVAARRAQLAAQRDALLDALAQRLPDWRVTA
                     PHGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVE
                     AVGRLAAVRYDLDRAGRPQWREATVIA"
     aSDomain        4098..5147
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS11830_Aminotran_1_2.
                     1"
                     /evalue="7.80E-30"
                     /label="GA0074696_RS11830_Aminotran_1_2.1"
                     /locus_tag="GA0074696_RS11830"
                     /protein_end="463"
                     /protein_start="113"
                     /score="96.1"
                     /tool="antismash"
                     /translation="IDLGVAALAAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREA
                     VARSYTARGLPTSAEQIMVTSGTQHALDLVLRLALAPGGSVLVESPTYPNALAALSARR
                     ARITTHGLAVDGAGWDADLLLGSIRQVRPKLAYLIPDFQNPTGHLMSAELRERVVAVAH
                     TAGTDLVVDESFVDLPLDGTELPPPAATFDRHSRVISIGGMSKPYWGGLRIGWVRASAP
                     QVQRLAAARVGVDMASPVLDQLVAVHLLADAPTIVAARRAQLAAQRDALLDALAQRLPD
                     WRVTAPHGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPA
                     ADLVEAVGRL"
     gene            5279..6568
                     /locus_tag="GA0074696_RS11835"
                     /old_locus_tag="GA0074696_2380"
     CDS             5279..6568
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018479.5"
                     /locus_tag="GA0074696_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2380"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_197700830.1"
                     /transl_table=11
                     /translation="MTDGGTTRRAPRMRAVTEGASVTPLELFFDLVFVYALTQVTALMA
                     GDLTWWGMLHGLLLLALLWWCWCCYAWLGNTVRADEGVVRVALFAVMGTMFVVAVTIPE
                     AFTDLPGGLSGPAVFAAGYLVVRVLHLVIYWHAARVQDDAALRRQLLRAALPMLAGATV
                     LFTAAVLPQQLADSPHQEDVIRTALWVLALVVDYGGIMAIGARGWQVYSAAHWTERHGL
                     IIIVALGESLVAIGVGVTALPISWPIVVASFLGIAVAAALWWAYFDVVSIAAERVLARA
                     EGAERAALARDSYTYLHLPMVAGIILLALGFKKVLSYVGDGTEHDLTDPLHGIGLYALY
                     GGVILYLLGHLGFRLRNMRSANRPRAVTAVLLVLLIPVADRLPALAALGLLAVVCVGMI
                     AVEVVLFGDARRKLRDAFLAEHGSAAAPEH"
     gene            6641..7978
                     /locus_tag="GA0074696_RS11840"
                     /old_locus_tag="GA0074696_2381"
     CDS             6641..7978
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072131.1"
                     /locus_tag="GA0074696_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2381"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_088961152.1"
                     /transl_table=11
                     /translation="MGAADRRPGAAGGGQRWSRGVRPGAPGSRTTRLELYYDVVFVFAF
                     LTVTTVTSSRPSVPNLIGCLLVLSLLWWCWTGFAIVGNAVRTDQGVLPLIGFVTLAATF
                     LLALSMPKAFVDRPGGLNGPLVFAGCYFLVRMSQLSVLGWVEWPDPARRRRWLLLASPP
                     VIATALLVTAALVPHRVADDAAERWLRLLLWSSALLVEYGAGVLLRGAYWAVLSAGHWA
                     ERHALIVLVALGESVIALGFGPRFVTELPLTWPVMAAAVLGIAVVSALWWAYFDTLALA
                     MEQALHGIREPAARARLARDAYTYLHLPLIAGIIFVALGLKDLLAEGAEPGTPAWGEPL
                     GGFWVLVLHGGVAVYLLGLAGLGWRTWGEVRWVPLATVVLLAALGPLSSRVPELAAVGL
                     LALVCGASTGAQTMVDGPRRRRTRQVALAEQEASEAEQSRWRGEHL"
     gene            complement(8036..9862)
                     /locus_tag="GA0074696_RS11845"
                     /old_locus_tag="GA0074696_2382"
     CDS             complement(8036..9862)
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 4.2e-91.
                     Score: 297.5. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS11845_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="GA0074696_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2382"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_088961153.1"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-90, bitscore:
                     299.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSIPDMFLKRVAATPDRHAFAHPGPDESGPVWLTWEQV
                     GQRAKAVAAGLHALGVGQEDPVAILANTRLDWVIADFGIMCAGGATTTVYPTTEPEDAV
                     YIIADSGSRVLFAENPAQAAKIAGAELPALTHVVLFDGAVDPAAAVPQLTLAELEEQGA
                     ARLAAEPDLIERLVAPIGPEHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAEMGLLR
                     DDDLQYLWLPLSHSFGKTLLCGATHVGLPTYVDGRIDKLVDLLSVVRPTLMCGAPRVFE
                     KVYNKAVTTAQSAGGAKAKIFAWGVRVGKEKVALEQAGQPVPAGLKLKYALAEKLVFSK
                     LQARLGGRMRVLVSGAAPLSKEIATFFAAANLPISEGYGLTETSAGNFVNPPEGLRIGT
                     VGRAMGDLECRIDTDGEILVKGTPVMRGYHNLPEETKAAFTEDGFFRTGDIGSLDDDGY
                     LRITDRKKDLVKTSGGKYIAPSHIEGMFKAICPYTSQAIVIGQARNYCTMLVTLDPDAI
                     KGWTAGGPLEGRDYAEVVASPEAKAMVEEYVAQLNAKLNRWETIKKVTILPRDLTIEHG
                     EVTPSLKIKRRGVETNFAAEIDKMYEGTLAEI"
     aSDomain        complement(8450..9820)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS11845_AMP-binding.1"
                     /evalue="4.20E-91"
                     /label="GA0074696_RS11845_AMP-binding.1"
                     /locus_tag="GA0074696_RS11845"
                     /protein_end="471"
                     /protein_start="14"
                     /score="297.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVAATPDRHAFAHPGPDESGPVWLTWEQVGQRAKAVAAGLHAL
                     GVGQEDPVAILANTRLDWVIADFGIMCAGGATTTVYPTTEPEDAVYIIADSGSRVLFAE
                     NPAQAAKIAGAELPALTHVVLFDGAVDPAAAVPQLTLAELEEQGAARLAAEPDLIERLV
                     APIGPEHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAEMGLLRDDDLQYLWLPLSHS
                     FGKTLLCGATHVGLPTYVDGRIDKLVDLLSVVRPTLMCGAPRVFEKVYNKAVTTAQSAG
                     GAKAKIFAWGVRVGKEKVALEQAGQPVPAGLKLKYALAEKLVFSKLQARLGGRMRVLVS
                     GAAPLSKEIATFFAAANLPISEGYGLTETSAGNFVNPPEGLRIGTVGRAMGDLECRIDT
                     DGEILVKGTPVMRGYHNLPEETKAAFTEDGFFRTGDIGSLDDDGYLRITDRKKDLVKT"
     CDS_motif       complement(8546..8620)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074696_RS11845_0002"
                     /evalue="7.40E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0074696_RS11845"
                     /protein_end="439"
                     /protein_start="414"
                     /score="24.7"
                     /tool="antismash"
                     /translation="GEILVKGTPVMRGYHNLPEETKAAF"
     CDS_motif       complement(9248..9307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0074696_RS11845_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0074696_RS11845"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     misc_feature    complement(9893..9908)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     misc_feature    9955..9972
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            complement(10001..10942)
                     /locus_tag="GA0074696_RS11850"
                     /old_locus_tag="GA0074696_2383"
     CDS             complement(10001..10942)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="GA0074696_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2383"
                     /product="terpene synthase family protein"
                     /protein_id="WP_088961154.1"
                     /sec_met_domain="T1TS (E-value: 2.4e-70, bitscore: 236.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGIAGSGLHEPPFPARRHSATGRVAAESLTWARSLGLVEDGPRW
                     HRLRAADAAELAGRACPRAPVDRLRLLTDLITWLFVVDDSCDEDDLGAEPGRLAPTVGA
                     LLDVLDRHGADGGAAPAGGPLGIALADICRRVRAHRRPALLLRLVAELREYLLALLWEA
                     ANRQQQRVPELAEYLQLRRHTGGVRPSLTLTDLAYDVRPGRGGRTDPAVLALDDLTTDL
                     VCWCNDLFSHRKELRGAPDPHNLVTVIAAGTGQDVDAAVRTAAGLFNDRLDHYLVGEAA
                     LAGDPVLAPFLEVRRSWIRATYDWSLRAVRYA"
     gene            complement(11183..11812)
                     /locus_tag="GA0074696_RS11855"
                     /old_locus_tag="GA0074696_2384"
     CDS             complement(11183..11812)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="GA0074696_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2384"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_088961155.1"
                     /transl_table=11
                     /translation="MPRYARSEREALVDLMLELGPDAPTVNEGWTTRDLAAHLVVRERR
                     PDAAGGIVLPPLRGYAERVRRRVAARPWAELVGLVRRPPLWSPVSNPLTDELANTLEFF
                     IHHEDVRRAATGWQPRDLPAGLRARLWKPAALLARAALRRFPADLLVQAPGHGELSVGR
                     GGERLRLVGSPGELALFLSGRQRVARVQVDGSAGLADRLRHASLGL"
     gene            11993..13870
                     /locus_tag="GA0074696_RS11860"
                     /old_locus_tag="GA0074696_2385"
     CDS             11993..13870
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="GA0074696_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088961156.1"
                     /transl_table=11
                     /translation="MASGTSRDVLGRGLSVLGRAIREQPRIFAVAVSGSVLFGLMVIAS
                     AYVVGAVVGEVVVPSIARGSVGTGALALAAAALFGISVLRVVGIFGRRLGAGYMQFRLQ
                     AAYRRRVTRRYLDLPLAWHQRNATGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     VSLFLTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAEETARFSARAGELRDALISVGRLRGVFDPLLETLPSLGTLAVLVVGAFRLR
                     AGAISVAELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATGEMPYGERR
                     LAPAEPTPATLAFADVCFGYEPAEAHLPGTEVLGEVTFTVPAGKTVALVGPTGAGKSTI
                     ASLAVRLVDPRVGTVALDGVDVRELAADSLAATVALVAQVPFVFDDTVRANITLDRPGI
                     GDEVVWAALRLAEADGFVAALPEGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRAPTGGQGAAASILVVAYRRATIALADEVIYVEQGRVVAR
                     GTHTELLATVPGYADLVTAYEQAEQEREQNRTYDEVAPLTSGLEIEVDR"
     misc_feature    13907..13920
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    13966..13979
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    14025..14038
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     gene            14044..15843
                     /locus_tag="GA0074696_RS11865"
                     /old_locus_tag="GA0074696_2386"
     CDS             14044..15843
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475811.1"
                     /locus_tag="GA0074696_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2386"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_231925336.1"
                     /transl_table=11
                     /translation="MSATTVEPERREEPQERSETTWRTLRRGLALSPELRTGLAGTLAL
                     ALVYMVGRVAVPVAVQRGIDGGIVGGLDLAVVWRVVTITAAVLVVTTTCGYLMMRRLFT
                     VSETALANVRTRAFRHVHDLSMLHQQSERRGSLVSRVTSDVDQITQFLQWGGVILLVNL
                     GQLVVTTAVMLAYSWQLTLVVLVAFAPAVLVIRLLQRRLGAAYGVVRQRMGTLLGAIAE
                     SVVGAPVIRAYGIAGRTARRLDTAIEGQRQAQQRAIRISIVGSSVGELAAGLALAGVVV
                     LGVLLGVDGSLSIGQLTAFLFLVTLFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVAPD
                     VADPGEQGRELPPGPLDISFAGVTFAYPGGPPVLHDVTLDIPAKSRVAVVGETGSGKTT
                     FAKLLTRLMDPTDGQVLLSGVPLDRVRFDSLRARVVMVPQDGFLFDATVGDNVRFARPE
                     LTDAELTAAFTELGLADWLDGLPSGLATAVGERGESLSVGERQLVALARAYVADPDLLV
                     LDEATSAVDPATEVRLQRTLDAVTRGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPH
                     DELVRDPESVYGLLFASWLEQTR"
     gene            complement(15912..16523)
                     /gene="rpsD"
                     /locus_tag="GA0074696_RS11870"
                     /old_locus_tag="GA0074696_2387"
     CDS             complement(15912..16523)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184792.1"
                     /locus_tag="GA0074696_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2387"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_088961157.1"
                     /transl_table=11
                     /translation="MNHPRPKARLSRALGIPLTRKCVQYLERRPYPPGVHGRARRRTSD
                     YQVRLLEKQRLRHQYNVSEVQLRRAFDEAARGAGKTGQTLVALLERRLDAVVHRAGLAR
                     SIYQARQLVAHGHLTVDGRKVDRPSYRLRPGQVVAVRERSRQLPPFQLAATGANADDGP
                     GRPYLSVDLTGLRATLLREPARHEVPVVCDEQLVVEHYSR"
     misc_feature    complement(16559..16577)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     gene            16593..17342
                     /locus_tag="GA0074696_RS11875"
                     /old_locus_tag="GA0074696_2388"
     CDS             16593..17342
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018824278.1"
                     /locus_tag="GA0074696_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2388"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_088961158.1"
                     /transl_table=11
                     /translation="MGPSPAEIVRTLVAGRLPGLVHLAHRPGPYHVRHATDPEGRVLML
                     VSVVSDLAAELDPGADDDVAVVLDVLDLPPAPGAPSLGRAWVSGWAVPLRGAEARRGAA
                     DFAAVDPTGDLLDVGTRFRLHRFEVVEARLEGADSVRRVDPGEYAAAEPDPLHTIEPEL
                     LADLTDHHEAQVAAYLRGHLDLAGGRPRVVRLDRYGLVVAYGGPGDRRRARLAFPHPVA
                     DPAELSRLLHPMLCPRAAGARPAADGR"
     gene            complement(17346..17942)
                     /locus_tag="GA0074696_RS11880"
                     /old_locus_tag="GA0074696_2389"
     CDS             complement(17346..17942)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287561.1"
                     /locus_tag="GA0074696_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2389"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_088961159.1"
                     /transl_table=11
                     /translation="MTRRRTGRRPGNPDTRQAILAAARTTFAERGFDAASIRVIATAAG
                     VDPALVHHYFGSKEELFRATVEIPLDPAELLPVVLAGGVDGVGERLVRTFLGVWDSPAG
                     KAAVALLRSAVNNDWTARLLREFLVTQVLRRVLDHLDIPPAELPLRGSLVATQMIGLAM
                     MRYVIRLEPVASADPETLVAALGPTVQRYLTGDLA"
     gene            complement(17939..18694)
                     /locus_tag="GA0074696_RS11885"
                     /old_locus_tag="GA0074696_2390"
     CDS             complement(17939..18694)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="GA0074696_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2390"
                     /product="ABC transporter permease"
                     /protein_id="WP_088961160.1"
                     /transl_table=11
                     /translation="MNARILTVTIGRILRQLRHDKRTVALLVVVPTVLLTLVYYMYADL
                     PTAPGQPSTFDRIALIMLGFFPFIVMFLVTSIAMLRERTTGTLERLLTTPLHKLDLLFG
                     YGIAFGLAGAVQAAIAAGVAYWLLGMETAGSAGLVILVAALNAVLAVALGLFCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRGQMAGWLQAVSDALPLSYAVEALQEVGAHAEPTG
                     TMWRDVGIVAGAAVAALVLAAATLRRRSG"
     gene            complement(18986..19729)
                     /locus_tag="GA0074696_RS11890"
                     /old_locus_tag="GA0074696_2391"
     CDS             complement(18986..19729)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020608815.1"
                     /locus_tag="GA0074696_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2391"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088961161.1"
                     /transl_table=11
                     /translation="MEDAITVRDLVVDRGRRRVLHGIDCTVPRGSVTGLLGPSGSGKTT
                     LMRAVVGVQVIDSGTVTVLGRPAGSADLRHRVGYLTQAPSVYADLTVRENARYFAALQG
                     RHGADADRAVADVGLADAATQLVGTLSGGQRSRASLACALVGDPELVILDEPTVGQDPV
                     LRADLWGRFHEMAAAGTTLLVSSHVMDEAARCDRLLLIREGRLVADDTPDAIRERTGVD
                     DLEESFLRLIRSSEAGQQPAGKEAS"
     gene            19836..20222
                     /locus_tag="GA0074696_RS11895"
                     /old_locus_tag="GA0074696_2392"
     CDS             19836..20222
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287558.1"
                     /locus_tag="GA0074696_RS11895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2392"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_088961162.1"
                     /transl_table=11
                     /translation="MDISTQEPALSVGEAAARVGLTTYTLRWYEQEGLVAPVGRDSAGR
                     RRYTESDLDWLLLLTRLRRTGMPVRDMRRYAELARQGDRTLGARRALFEAHRARVLARM
                     AELEEDLKVLNYKIDLYRRAEEGR"
     misc_feature    complement(20652..20666)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 ggacctggcg gtcccgaagg agatgggcgg cgccggtggc gcggccaacc ccgagcagct
       61 cttcgccgcc ggctacgcgg cctgcttcca ctcggcgctg cgcctggtcg cccgccgggc
      121 caaggccgac gtctccggct ccgtggtcga ggccgaggtc ggcatcggcc cgaacggcag
      181 cggcggcttc ggcctgaccg tcgccctcct ggtcgacctg cccgccgtcg agcgggccgc
      241 cgccgagcag ctggtcgcgc aggcccacca ggtctgcccg tactcgaacg cgacccgcgg
      301 caacatcgag gtcgccctca ccgtccgcga ggccgccgcg gcctgagcgc cgcccggccc
      361 tgatcccccg cgtacgaaag gacgacaccg tgagcaccaa ccgcgagatc cacctggcct
      421 cccgccccca gggctggccg accgccgaca acttccgcct cgtcgagacc gaggtgccga
      481 cgcccggccc gggccagatc gtggtccgta accagttcat gtcggtcgac ccgtacatgc
      541 gggggcggat gaacgacgtg aagtcgtacg ttccgccgtt ccagctcggg gcgccgctcg
      601 acggcggcgc ggtcggcgag gtcgtggcca gcgaggccga cggcgtcaag gtcggcgaca
      661 ccgtgctgca cggcctcggc tggcgggagt acgcactgct cgacgccaag gccgcccgcc
      721 cggtcgaccc gacgatcgcg ccggtgagcg cgtacctgag cgtgctcggc atgaccggtc
      781 tgaccgcgta cgccgggctg ctcgacgtgg ccggcatgaa gccgggggag agcgtcttcg
      841 tctccgccgc cgccggctcg gtcggcagcc tggtcggcca gatcgccaag ctcaagggcg
      901 ccgggcacgt ggtcggcagc gccgggtcgc cggccaaggt cgagcggctc aaggcgctcg
      961 gcttcgacgc cgccttcgac taccacgacg gcccggtacg cgactcgctc aaggcggccg
     1021 cccccaacgg catcgacgtc tacttcgaca acgtcggcgg cgaccacctg gaggcggcga
     1081 tctcggcgat gaacctgcac ggccgggccg ccatctgcgg catgatcgcc cagtacaacg
     1141 acaccgagcc gccggccgcc ccgcgcaacc tggcaatggt catcggcaag cggctcaccc
     1201 tgcgcggctt cctcgtcaat gaccacggca acctgcgcga gcagttcgtg cgggacgtct
     1261 ccggctggct gcgcgacggg aagctctcgt acgacgagac gatcgtcgac ggcatcgaga
     1321 acgcccccgc ggcgttcctc ggcctgctgc gcggcgagaa cctgggcaag atgctcgtcc
     1381 gggtgtgagt cccgatccga cgcgcggcgg tggccggcct cacaggccgg tcgccgccgc
     1441 gtttccgttg gataggctcg ccccatgacg gtggcggtac gggtgattcc ctgtctggac
     1501 gtggacgccg ggcgggtggt caagggggtc aacttcctcg acctgcgcga cgccggcgac
     1561 ccggtggagc tggccgcggc gtacgaccgg gccggcgcgg acgagttgac cttcctcgac
     1621 gtcaccgcct cctccagcga ccgggggacc atgctcgacg tggtccggcg caccgcggag
     1681 tcggtcttca tcccgctgac cgtgggcggc ggcgtccggc aggtcgccga cgtcgacacg
     1741 ctgctgcggg ccggcgcgga caaggtcggg gtgaacaccg ccgcgatcgc ccgcccggag
     1801 ctgatcgccg agatcgccga ccggttcggc cggcaggtgc tggtgctctc gctggacgtg
     1861 cgccgggctc cggcgggcac cacgcccagc gggttcgagg tgaccaccca cggcggccgc
     1921 cggggcaccg gcctggacgc ggtcgagtgg gcgcggcgcg gcgccgagct gggggcgggg
     1981 gagatcctgc tcaactcgat ggacgccgac ggcaccaagg ccggcttcga cctggcgctg
     2041 atccaggcgg tccgcgcggt ggtggacgtg ccggtggtgg ccagcggcgg cgccggcgcg
     2101 gtggcgcact ttccgccggc catcggcgcg ggcgccgacg cggtgctcgc ggcgagcgtc
     2161 ttccacttcg gcgagctgac cgtcggcgag gtcaaggacg cgctgaaggc cgccggtcac
     2221 ccggtgcgct gaggcgcgcg ggcccggcca cgccgtcacc ccgccgggtc tgtcacccgg
     2281 cgccgcgcgc tgggggtcct cggccgtgct ccgtgcgtgt cggggtcaag ggacaaggtc
     2341 cggtgtgggc ctgatacctc tcaggtatca atatgaccct gaggtatcac cggcaccatc
     2401 gtggtgcctt ccgccggctc cgctacgcga cctccggtca gcggtcggcg agcgcggcct
     2461 ccgggccgcc ccaccggcca gcccgccggc gccgctggcc ccgccgccgg cgcctccgcg
     2521 cctcggcagc tcagcggccg gtccgcccct ccggcgagcg gcgcggggcc gggatcgacc
     2581 ggacgatgta ctcctggacg gcggcggcgt ggtcctcctc gggcaggtgc cactcggcgc
     2641 taccgggggt gtgccgccgg accagcaccc cctgcacggt gtccaccgtg gtgcccacgc
     2701 ccgcgctcgg ccgggtgcgc cagagccgct ccccgtcggg ggtgatccgg aaccagccgt
     2761 cggagacact gaccaggccg gcgccggcca gccggcggac cgccgcctcg acgtcctccc
     2821 gctccgggat cgcctggttg aggtgctccg cggtggagag cacgtcggtc agccggacgc
     2881 cctccgggcg tctggtgtcc gccgcgcggc ggtgccgccc ggcgccgctc gcgatcacca
     2941 gtgacacgaa gatccaggcg tccgtccagc gccatccgct ctcccccatg cacgaatgat
     3001 gcccggcggg gtcgatggag gaaacaccta ctttcccgct gtgacgtcag cgcagctcag
     3061 cgagggtgac caccggagtg tccggggtgg accggggcgg aacggtgaac agcggggtga
     3121 acaactgggc cagtgggccg atggcgaggg cgtacgcgac ggtgccgatg cccgccgtgc
     3181 cgccgagcag ccagcccagg gccagcacgg tcacctcgat gccggtgcgg atcagccgca
     3241 ccgagctgcc cgggcgccgg gcgaccagcc cggtcatcag gccgtcgcgc gggccggggc
     3301 cgaggtcggc gccgaggtag aggccggtcg cgacgccgtt ggcgacgatg ccggtcacca
     3361 gcaggccgat ccgcgccggc agcggcaggt ccgccgggag cagcgccacg gcggcgtcca
     3421 cggccaggcc gatcaccacc acgttgctga ccgtgccgag cccgggccgc tgccgcagcg
     3481 ggatccagag cagcagcacc accgcgccga ccaggatgct cgccgtgccg accgagatgc
     3541 cggtctgtcg ggacaggccc tggtggaaga cgtcccacgg gttcagcccg aggccggagc
     3601 ggatcatcag cgccatgctg acgccgtaga ggaccagccc gacgtagagc tgggtgagcc
     3661 gccggaccgg ccggtgccgc agattgccaa tcgctgccat gcatgccacc ctaggtgcca
     3721 atcgtggcga gagaagagcc aatttgggag gggtggccgt gaccagccag gtgcggggag
     3781 cccaattggc tcggctgctg gggcagtggc acgcgcttcc gggccgccgt cgcagcccgg
     3841 actacgccgc gctcgccgcc gcggtccgcg gcctgctcgc cgacggccgg ctccccctcg
     3901 gggtacgcct gccggccgag cgggagctgg ccgaggcgtt gcggatcagc cggaccacgg
     3961 tcaccgcggc gtaccggcag ctgcgcgaga ccgggcacct ggccagccgg cgcggggcgg
     4021 gcagctggac catgctgccc ggcacccacc gggtggccag caccgggctc tggaccccgc
     4081 tggacgaccg cgacatgatc gacctgggcg tcgccgcgct ggccgccccg ccgcagctcg
     4141 tgccggccgc ccgcgccgcc gccgaggacc tgccccgcta tctcggcggc gccggctacc
     4201 acccgaccgg gatcatcgag ctgcgcgagg cggtcgcccg gtcgtacacc gcccgggggc
     4261 tgcccaccag cgccgagcag atcatggtga ccagcggtac ccagcacgcg ctggacctgg
     4321 tgctccggct ggcgctggcg cccggcggca gcgtgctggt ggagtccccg acctatccga
     4381 acgcgctggc cgcgctgtcc gcccggcggg cccggatcac cacccacgga ctggccgtcg
     4441 acggggccgg ctgggacgcc gacctgttgc tgggcagcat ccgccaggtc cggcccaagc
     4501 tggcctacct gatccccgac ttccagaacc cgactggtca cctgatgtcg gccgagctgc
     4561 gcgaacgggt ggtcgccgtc gcccacaccg ccggcaccga cctggtcgtc gacgagtcgt
     4621 tcgtggatct cccgctggac ggcaccgagc tgcccccacc ggcggccacc ttcgaccggc
     4681 acagccgggt gatcagcatc ggcgggatga gcaagccgta ctggggtggg ctgcggatcg
     4741 gctgggtacg cgcctccgcg ccgcaggtgc agcggctggc cgcggcccgg gtcggcgtcg
     4801 acatggccag cccggtgctg gaccagctgg tcgcggtgca cctgctcgcc gacgcgccga
     4861 ccatcgtcgc cgcccgccgg gcccagctcg ccgcacagcg cgacgccctg ctcgacgcgc
     4921 tcgcgcagcg cctgcccgac tggcgggtca ccgcgccgca cggcggggta accctctggg
     4981 ccgagctgga cgggccgatc tccagcgcgc tggcccgggc cgccgaggag gtcggcgtac
     5041 gcctggcgcc cggcccccgg ttcggcctgg acgggacgct ggaacgcttc ctgcggctgc
     5101 ccttcaccct gcccgccgcc gacctggtcg aggcggtggg ccggctcgcc gcggtccgct
     5161 acgacctgga ccgggccggg cgtccgcagt ggcgggaggc gacggtcatc gcctgagccc
     5221 gacgcggtgg acccaccggg gacgccacgc cgtgatcccg gctgccagac tgtgcgccgt
     5281 gacggacggc ggtacgacgc ggcgcgcgcc gcggatgcgg gccgtgaccg agggcgcctc
     5341 ggtcaccccg ctggaactct tcttcgacct ggtcttcgtc tacgcgctca cccaggtgac
     5401 cgcgctgatg gcgggggacc tgacctggtg gggcatgctg cacgggctgc tcctgctggc
     5461 cctgctctgg tggtgctggt gctgttacgc ctggttgggc aacacggtgc gcgcggacga
     5521 gggggtggtc cgggtggcgc tgttcgcggt gatgggcacc atgttcgtcg tcgcggtgac
     5581 cattcccgaa gccttcacgg acctgcccgg cgggctctcc gggccggccg tcttcgcggc
     5641 cggctacctg gtggtccggg tgctgcacct ggtgatctac tggcacgccg cccgggtcca
     5701 ggacgacgcc gcgctgcgcc ggcaactgct gcgggcggcc ctgccgatgc tggccggggc
     5761 caccgtgctg ttcaccgccg ccgtgctgcc ccagcagctc gccgactccc cgcaccagga
     5821 ggatgtcatc cggacggcgc tctgggtgct cgccctcgtc gtcgactacg gcggcatcat
     5881 ggccatcggc gcgcgaggct ggcaggtcta ctccgccgcg cactggaccg agcgacacgg
     5941 gctgatcatc atcgtcgcgc tcggcgagtc gctggtggcg atcggcgtcg gggtgaccgc
     6001 gctgccgatc tcctggccca tcgtcgtcgc gtcgttcctc ggcatcgcgg tggccgccgc
     6061 gctctggtgg gcgtacttcg acgtggtctc gatcgccgcc gagcgggtac tggcccgggc
     6121 cgagggcgcc gagcgggccg cgctggcccg cgactcctac acgtacctgc acctgccgat
     6181 ggtggccggc atcatcctgc tcgccctcgg cttcaagaag gtcctgtcgt acgtcggcga
     6241 cggcaccgag cacgacctga ccgacccgct gcacggcatc ggcctgtacg ccctctacgg
     6301 cggggtgatc ctctacctcc tcggccacct gggcttccgg ctgcgcaaca tgcgttcggc
     6361 caaccggccg cgagcggtga ccgccgtgct gctggtgctg ctgatcccgg tcgccgaccg
     6421 cctgccggcg ctggccgccc tcggactgct cgccgtggtc tgcgtcggga tgatcgcggt
     6481 ggaggtggtg ctcttcggcg acgcccggcg caagctgcgc gacgccttcc tcgccgagca
     6541 cgggtccgct gcggcgcccg agcactagac cggccgcccg accgggtggg gttgcgccga
     6601 tccaccccgg ccacgccggg cctgctggga cactgcgggg gtgggggcag cggaccggcg
     6661 gccgggcgcg gcgggcggcg gccaacgctg gtcgcgcggg gtccgccccg gcgcgccggg
     6721 gtcccggacc acccggctgg agctgtacta cgacgtcgtc ttcgtgttcg ccttcctcac
     6781 cgtcaccacg gtgacgtcga gccggccgtc ggtgcccaac ctgatcggct gcctgctggt
     6841 gctgtcgctg ctctggtggt gctggaccgg gttcgccatc gtcggcaacg cggtccgcac
     6901 cgaccagggc gtgctgccgc tgatcggctt cgtcaccctg gccgccacct tcctgctcgc
     6961 gctcagcatg cccaaggcgt tcgtggaccg gccgggcggg ttgaacggcc cgctcgtctt
     7021 cgccggttgc tacttcctgg tccggatgtc gcagctgtcg gtcctcggct gggtggagtg
     7081 gcccgacccg gcccgccgcc ggcggtggtt gctgctggcc agcccgccgg tgatcgcgac
     7141 cgcgctgctg gtcaccgccg ccctggtgcc gcaccgggtc gccgacgacg ccgccgagag
     7201 gtggttgcgg ctgctgctct ggtcgtcggc gctcctggtc gagtacgggg cgggcgtgct
     7261 gctgcgtggc gcctactggg cggtgctgtc ggccgggcac tgggcggaac ggcacgcgct
     7321 gatcgtgctg gtcgcgctcg gcgagtcggt catcgcgctg ggcttcggcc cgcggttcgt
     7381 caccgagttg ccgctgacct ggccggtgat ggcggccgcc gtgctcggca tcgcggtggt
     7441 ctcggcgctg tggtgggcct acttcgacac cctcgccctg gcgatggagc aggcgctgca
     7501 cggcatccgg gaacccgccg cgcgggcgcg cctcgcccgg gacgcgtaca cctacctgca
     7561 cctgccgctg atcgccggga tcatcttcgt cgccctgggg ctcaaggacc tgctggccga
     7621 gggtgcggag ccgggcacgc cggcctgggg ggagccgctg ggcggcttct gggtgctggt
     7681 gctgcacggc ggggtggccg tctacctgct cggcctggcc gggctggggt ggcggacatg
     7741 gggcgaggtg cggtgggtgc cgctggcgac ggtggtgctg ctcgcggccc tcgggccgtt
     7801 gtccagccgg gtgcccgaac tggccgcggt ggggctgctg gcgctcgtct gcggcgcctc
     7861 caccggggcg cagacgatgg tcgacggccc ccgccggcgc cggacccggc aggtggcgct
     7921 ggcggagcag gaggcgtcgg aggccgagca gagcaggtgg cggggcgagc acctgtgagc
     7981 ggacgcccgg gtggccgtgc ctggcgaggt taccggccac ggccacccga ggcggtcaga
     8041 tctcggccag cgtgccctcg tacatcttgt cgatctcggc ggcgaagttg gtctccacgc
     8101 cgcgtcgctt gatcttcagc gacggggtca cctcgccgtg ctcgatggtc aggtcgcgcg
     8161 gcaggatggt gaccttcttg atcgtctccc accggttgag cttcgcgttg agctgcgcga
     8221 cgtactcctc gaccatggcc ttcgcctcgg gcgaggccac gacctcggcg tagtcccggc
     8281 cctccagcgg tccgccggcc gtccagccct tgatcgcgtc cgggtccaga gtgaccagca
     8341 tggtgcagta gttgcgggcc tggccgatca cgatcgcctg cgaggtgtac gggcagatcg
     8401 ccttgaacat gccctcgatg tgcgacgggg cgatgtactt gccgccggag gtcttgacca
     8461 ggtccttctt gcggtcggtg atccgcaggt agccgtcgtc gtcgaggctg ccgatgtcgc
     8521 cggtgcggaa gaagccgtcc tcggtgaacg cggccttcgt ctcctcgggc aggttgtggt
     8581 agccgcgcat caccggcgtg cccttgacca ggatctcgcc gtcggtgtcg atccggcact
     8641 ccaggtcgcc catcgcccgg ccgacggtgc cgatgcgcag cccctccggc gggttgacga
     8701 agttgccggc gctggtctcg gtcaggccgt acccctcgga gatgggcagg ttcgcggcgg
     8761 cgaagaaggt ggcgatctcc ttgctcagcg gcgccgcgcc ggagaccagc acccgcatcc
     8821 ggccgccgag gcgggcctgg agcttgctga agaccagctt ctcggccagc gcgtacttca
     8881 gcttcagccc cgccgggacc ggctggccgg cctgctccag cgcgaccttc tccttgccga
     8941 cgcggacccc ccaggcgaag atcttcgcct tcgcgccgcc ggcgctctgg gccgtggtga
     9001 cggccttgtt gtagaccttc tcgaagaccc ggggcgcgcc gcacatcagc gtcggccgca
     9061 ccacgctgag caggtcgacc agcttgtcga tccgcccgtc cacgtacgtc ggcaggccga
     9121 cgtgggtggc gccgcagagc agcgtcttgc cgaacgagtg cgacagcgga agccagaggt
     9181 actgcaggtc gtcgtcgcgc agcagcccca tctcggcctg cgccacgccc tcccagcacc
     9241 agccgccgtg cagcagctcg acgcccttgg gtcggccggt ggtgcccgag gtgtagatca
     9301 gggtggccag gtgctccggg ccgatcgggg cgacgagccg ctcgatcagg tccggctcgg
     9361 ccgccagtcg cgccgcgccc tgctcctcca gctccgccag ggtgagctgg ggtacggccg
     9421 cggccgggtc gacggcgccg tcgaagagca ccacgtgggt gagcgcggga agctccgccc
     9481 cggcgatctt ggcagcctgg gccgggttct cggcgaagag cacccgggag ccggagtcgg
     9541 cgatgatgta gaccgcgtcc tcgggctcgg tggtggggta gaccgtggtg gtcgcgccgc
     9601 cggcgcacat gatgccgaag tcggcgatca cccagtccag ccgggtgttg gccaggatcg
     9661 ccaccggatc ctcctggccg acgcccagcg cgtgcaggcc ggcggcgacc gccttggccc
     9721 gctgtccgac ctgctcccac gtcagccaga cggggccgga ctcgtccggg cccgggtggg
     9781 cgaacgcgtg ccggtcgggg gtggcggcca cgcgcttgag gaacatgtcg ggaatggaac
     9841 ggtacggtac atcgagagcc atcgctgtag ccgccttcag ggggtggatg gacgtgacgg
     9901 gggtcacgcc gttctgcggt taccgaagag tattgcctgc accggggcat cggctagccc
     9961 cgaaagcggt gagccgaccg tgtcccgcga ggtggaacgc tcaggcgtac cggacggccc
    10021 gcagcgacca gtcgtaggtg gcccggatcc aggaccggcg cacctccagg aagggtgcca
    10081 ggaccgggtc accggccagc gccgcctcac cgacgaggta gtggtccagc cggtcgttga
    10141 acagtccggc cgccgtgcgg acggcggcgt cgacgtcctg cccggtgccg gccgcgatga
    10201 cggtgaccag gttgtgcggg tcgggcgcgc cgcgcagctc cttgcggtgc gagaagaggt
    10261 cgttgcacca gcagaccagg tcggtggtga ggtcgtcgag ggcgagcacc gccgggtcgg
    10321 tgcgtcctcc ccggccgggc cggacgtcgt acgccagatc ggtcagggtg aggctggggc
    10381 gtacgccgcc ggtgtgccgg cgcagctgaa ggtactcggc cagctccggc acccgctgct
    10441 gctgccggtt ggccgcctcc cagagcaggg ccagcaggta ctcccgcaac tcggccacca
    10501 gtcgcagcag cagcgccgga cggcggtgcg cgcgtacccg ccgacagatg tcggccagcg
    10561 cgatgcccag cggcccgccg gcgggcgccg ccccgccgtc ggcgccgtgc cggtcgagga
    10621 cgtccagcag cgcgccgacg gtcggcgcga gccggcccgg ctcggccccg aggtcgtcct
    10681 cgtcgcagct gtcgtccacc acgaacagcc aggtgatcag gtcggtgagc agccgcagcc
    10741 ggtccaccgg cgcccgtggg caggcccggc cggcgagttc ggcggcgtcg gcggcccgca
    10801 gtcggtgcca gcgcggcccg tcctccacca gcccgaggct ccgggcccag gtcaggctct
    10861 ccgcggcgac ccggccggtg gcggagtgcc gccgggcggg gaaggggggc tcgtgcagtc
    10921 ccgacccggc gatgccgcgc atggtgcccc ctgtccgccg cccggaacgg gatcggcggg
    10981 cagaagagta cgacacctca cattggcggg aatcgctcgg cgcgcatggt gggaaaactc
    11041 ctcgtggccg gtttcgcaca cccggaaccc gccgctggcg gcaatcgtcc ggctctggtc
    11101 ggaatcggtc gacctgccga gcagcacttc tgatcacctg gccgcgccgg tccagccagc
    11161 cggacggcgt cgggtccgga ggtcagaggc cgagcgaggc gtggcggagc cggtcggcga
    11221 ggccggcgga gccgtcgacc tggacccggg ccacccgctg ccggcccgag aggaagagcg
    11281 ccagctcgcc cggcgacccg accagccgga gccgttcgcc gccccggccc accgacagct
    11341 cgccgtggcc gggcgcctgc accagcaggt cggccgggaa ccggcgcaac gccgcccggg
    11401 ccagcagggc ggccggcttc cacagccgcg cccgcaggcc ggccggcagg tcacgcggct
    11461 gccatccggt cgcggcccgc cggacgtcct cgtggtggat gaagaactcc agggtgttgg
    11521 ccagctcgtc ggtgagcggg ttgctcaccg ggctccacag cggcgggcgg cgcaccaggc
    11581 cgaccagctc cgcccagggg cgggcggcga cccgccggcg cacccgctcg gcgtacccgc
    11641 gcagcggcgg gagcacgatg ccgccggcgg cgtccgggcg acgctcgcgc accaccaggt
    11701 gggcggcgag gtcgcgggtc gtccacccct cgttgacggt cggtgcgtcc ggtcccagct
    11761 ccagcatgag atcgacgagc gcctcgcgct ccgatcgggc gtaccgcggc atgagggtga
    11821 tcgtaggcgc gccggccggt gtcggcgcgc cggagcgcgt gccgcggtga ccggggcgcg
    11881 ccggagtgtg ccagagggca cgtgacggcg gacataccgg gtccgggtcg gcggaggtgg
    11941 ccgggagcgg taaggatgag ggggaacagg gcggcttacg gcgggggaca gtgtggcgag
    12001 cgggacaagt cgggacgtgc tcggcagggg actgtcggtc ctcggccggg cgatccggga
    12061 acaaccgcgg atcttcgcgg tggcggtgag cggcagcgtg ctcttcggcc tcatggtcat
    12121 cgccagcgcg tacgtggtgg gcgcggtggt cggcgaggtg gtggtgccgt ccatcgcccg
    12181 cggctccgtc gggacgggcg cgctggccct ggccgcggcg gcgctgttcg gcatcagcgt
    12241 gctgcgggtg gtgggcatct tcggccgccg gctcggcgcc ggctacatgc agttccgcct
    12301 ccaggccgcc taccggcgcc gggtcacccg ccgctacctc gacctgccgc tggcctggca
    12361 ccagcgcaac gccaccggca ccctgctgtc caacgccaac tcggacgtgg aggcggcctg
    12421 gtacccgatc gccccgctgc ccttcgcggt cggcaccctg gtcatgctgg tcggggcggt
    12481 cgtctcgctc ttcctcaccg actgggcgct ggccctggtc gggctggctg tcttcccggc
    12541 gctcttcgcg ctcaacgtgg tctactcccg gcggatggca ccccggcagg cccgcgccca
    12601 gcggctgcgc gccgaggtca gcggcatcgc ccacgagagc ttcgacggcg ccctggtggt
    12661 caagacgatg ggccgcgagg ccgaggagac cgcccggttc tcggcccggg ccggcgagct
    12721 gcgcgacgcg ctgatctccg tcggccggct gcgcggcgtc ttcgacccgc tgctggagac
    12781 gctgcccagc ctcggcaccc tcgccgtgct ggtggtcggt gcgttccggc tgcgggcggg
    12841 cgcgatcagc gtcgccgagc tggtcagcgt cgccttcctc ttcaccgtgc tggccttccc
    12901 ggtgcgggcc atcggctggg tcctcgccga gctgccgcgc agcgtcgccg gctgggaccg
    12961 ggtccgccgg gtcctggacg ccaccggcga gatgccgtac ggcgagcgtc ggctcgcccc
    13021 ggccgagccg acacccgcca cgctggcctt cgccgacgtc tgcttcgggt acgagccggc
    13081 cgaggcgcac ctgcccggca cggaggtgct cggcgaggtc accttcaccg tgccggccgg
    13141 gaagacggtc gccctggtcg gcccgaccgg cgccggcaag tccaccatcg cctcgctggc
    13201 cgtgcgcctg gtcgacccgc gcgtcggcac ggtggccctg gacggcgtcg acgtacgcga
    13261 gctggccgcg gactcgctgg cggcgacggt cgccctggtc gcgcaggtgc cgttcgtctt
    13321 cgacgacacc gtgcgggcca acatcaccct ggaccggccg ggcatcggcg acgaggtcgt
    13381 gtgggccgcg ctgcggctgg ccgaggcgga cggcttcgtc gccgcactcc ccgaggggct
    13441 ggacaccatg gtcggcgagc ggggcacctc gctctccggc gggcagcggc agcggctcac
    13501 cctggcccgg gcgctcgccg gccggccccg gctgctggtg ctcgacgacg cgaccagcgc
    13561 cgtcgacccg agggtggagg cggccatcct ggccggactg cgcgccccga ccggggggca
    13621 gggcgccgcc gcgtcgatcc tggtggtcgc gtaccggcgg gcgaccatcg ccctcgccga
    13681 cgaggtgatc tacgtggagc aggggcgggt ggtggcccgg ggcacgcaca ccgagctgct
    13741 cgccaccgtg cccggctacg ccgacctggt gaccgcgtac gagcaggccg agcaggaacg
    13801 cgagcagaac cgcacgtacg acgaggtcgc gccgctgacc tcgggcctgg agatcgaggt
    13861 ggaccggtga gcgcgaggag tgcagcggag cggagccccg cagtcgcgaa cgaaaggtcg
    13921 gcccggtgag cgcgaggagt gcagcggagc ggagccccgc agtcgcgaac gaaaggtcgg
    13981 cccggtgagc gcgaggagtg cagcggagcg gagccccgca gtcgcgaacg aaaggtcggc
    14041 ccggtgagcg cgacgacggt ggagccggag cggcgtgagg agccgcagga gcgttccgag
    14101 acgacctggc ggacgctgcg gcgcgggctg gcgctctccc cggaactgcg gaccgggctg
    14161 gccggcaccc tggcgctggc cctggtctac atggtcggcc gggtggccgt gccggtcgcc
    14221 gtgcagcgcg gcatcgacgg cggcatcgtc ggcggcctgg acctggccgt ggtgtggcgg
    14281 gtggtcacga tcaccgcggc cgtgctggtg gtcaccacca cctgcggcta cctgatgatg
    14341 cgccggctgt tcacggtcag cgagaccgcg ctggccaacg tccggacccg ggcgttccgg
    14401 cacgtgcacg acctgtcgat gctgcaccag cagtccgagc ggcgcgggtc gctggtctcc
    14461 cgggtgacca gcgacgtcga ccagatcacc cagttcctgc agtggggcgg ggtgatcctg
    14521 ctcgtcaacc tcggtcagct cgtcgtcacc acggccgtga tgctggcgta ctcctggcag
    14581 ttgaccctgg tggtgctggt cgccttcgcg ccggcggtgc tggtgatccg gctgctccag
    14641 cgccggctcg gcgccgccta cggggtggtc cggcagcgga tgggcaccct gctcggcgcc
    14701 atcgccgaga gcgtggtcgg cgcgccggtg atccgggcgt acggcatcgc ggggcgcacc
    14761 gcccggcggc tcgacaccgc gatcgagggg cagcggcagg cccagcagcg ggcgatccgg
    14821 atcagcatcg tgggcagctc ggtgggggag ctggccgccg gcctggcgct ggccggcgtg
    14881 gtggtcctcg gggtgctgct cggcgtggac ggctcgctct ccatcggcca gctcaccgcg
    14941 ttcctgttcc tggtcacgct cttcatccag ccggtgcaga tcgccaccga ggtgctcaac
    15001 gaggcgcaga acgccatcgc cggctggcgt cgggtgctgg acgtgctcga cgtcgcgccg
    15061 gacgtggccg accccggcga gcaggggcgg gagctgccgc cgggcccgct ggacatcagc
    15121 ttcgccgggg tgaccttcgc gtacccgggc ggtccgccgg tgctgcacga cgtcaccctg
    15181 gacatcccgg cgaagagccg ggtggcggtg gtcggcgaga ccggcagcgg caagaccacc
    15241 ttcgccaagc tgctcacccg gctgatggac ccgaccgacg ggcaggtgct gctctccggg
    15301 gtgccgctgg accgggtgcg gttcgactcg ctgcgcgccc gggtggtgat ggtgccgcag
    15361 gacggtttcc tcttcgacgc cacggtgggc gacaacgtcc gcttcgcccg ccccgagctg
    15421 accgacgcgg aactcaccgc ggccttcacc gagctggggc tggccgactg gctggacggc
    15481 ctgccgtcgg gcctggccac cgcggtcggc gagcggggtg agtcgctgag cgtgggggag
    15541 cggcagctgg tggcgctcgc ccgggcctac gtggccgacc cggacctgct ggtcctcgac
    15601 gaggccacca gtgccgtcga cccggccacc gaggtacgcc tgcagcgcac cctggacgcg
    15661 gtgacccgcg gccggaccac cctggccatc gcgcaccggc tctccaccgc gcaggcggcc
    15721 gacgaggtga tcgtggtgga ccggggccgg atcgtgcagc gcggcccgca cgacgagctg
    15781 gtccgcgacc cggagtcggt ctacggcctg ctcttcgcct cctggctgga gcagacccgc
    15841 tgacccgttg agcccgatac agcagacccg ttgagccgga tccggcgcgt cgcgcgccgg
    15901 atccggtcgg ctcaccggga gtagtgctcg accaccagct gctcgtcaca gaccaccggc
    15961 acctcgtgcc gggccggctc gcgcagcagg gtggcccgca ggccggtcag gtcgaccgag
    16021 aggtacggcc ggccgggccc gtcgtccgcg ttggccccgg tggcggcgag ctggaagggc
    16081 ggcagctgcc ggctccgctc gcggacggcg accacctgac cgggccgcag ccggtacgac
    16141 ggccggtcga ccttgcgccc gtcgacggtg aggtgcccgt gggcgaccag ttgccgggcc
    16201 tggtagatgc tgcgggccag gccggcgcgg tgcaccaccg cgtccagccg ccgttccagc
    16261 agcgcgacca gcgtctggcc ggtcttgccg gcgccccgcg ccgcctcgtc gaaggcgcgg
    16321 cgcagctgca cctcgctgac gttgtactgg tgccgcagcc gctgcttctc cagcagccgc
    16381 acctggtagt cggaggtgcg ccggcgggcc cggccgtgca cgcccggcgg gtaggggcgg
    16441 cgttcgaggt actggacgca cttgcgggtc agtgggatgc cgagggcccg ggagaggcgg
    16501 gccttggggc gggggtggtt cacgtggacg tctccgctcg ggtgttctag ggtgctactt
    16561 aggtaagcct aacctatata ggaggtgccc cgatgggacc gagccccgcc gagatcgtcc
    16621 gcaccctggt cgccggtcgg ctccccggtc tggtgcacct cgcgcaccgc ccgggcccgt
    16681 accacgtccg gcacgccacc gacccggagg gacgggtgct gatgctcgtg tcggtggtca
    16741 gcgacctcgc cgccgagctg gaccccgggg ccgacgacga cgtcgccgtg gtgctcgacg
    16801 tgctggacct gccgccggcg ccgggtgcgc cgtcgctcgg tcgggcctgg gtctccggct
    16861 gggcggtgcc gctgcggggc gcggaggccc ggcgcggtgc ggccgacttc gcggccgtcg
    16921 acccgaccgg tgacctgctc gacgtcggca cccggttccg cctgcaccgc ttcgaggtgg
    16981 tcgaggcccg cctggagggc gccgactccg tgcgccgcgt cgaccccggg gagtacgccg
    17041 ccgccgagcc ggacccgctg cacacgatcg agcccgagct gctggccgac ctcaccgacc
    17101 accacgaggc gcaggtcgcc gcgtacctgc gcggccacct cgacctcgcc ggcggccggc
    17161 cccgggtggt gcggctggac cggtacggcc tggtggtcgc gtacggcggg cccggcgacc
    17221 ggcggcgggc ccggctggcc ttcccgcacc cggtggccga cccggcggag ctgtcccggc
    17281 tgctgcaccc gatgctctgc ccgcgcgcgg ccggcgcccg cccggcggcc gacgggcgct
    17341 gacggtcagg ccaggtcgcc ggtgaggtag cgctgcaccg tcgggccgag cgccgcgacc
    17401 agggtctccg ggtccgcgga ggccaccggc tccagccgga tgacgtaccg catcatggcc
    17461 aggccgatca tctgggtggc caccagcgag ccgcgcagcg gcagctccgc cggcgggatg
    17521 tcgaggtggt cgagcacacg gcgcagcacc tgggtgacca ggaactcgcg cagcagccgg
    17581 gcggtccagt cgttgttgac cgccgagcgg agcagggcca ccgccgcctt gccggccggc
    17641 gagtcccaca ccccgaggaa cgtccggacc agccgctcac cgacgccgtc caccccgccg
    17701 gccagcacca cggggagcag ctccgccggg tccagcggga tctcgacggt ggcccggaag
    17761 agctcctcct tgctgccgaa gtagtggtgc accagggccg gatcgacccc cgccgcggtg
    17821 gcgatgaccc ggatcgaggc cgcgtcgaag ccgcgctcgg cgaaggtcgt ccgggccgcc
    17881 gcgaggatgg cctgccgggt gtccgggttg ccggggcgcc ggccggtgcg gcgccgcgtc
    17941 atccgctgcg ccgccgcagg gtcgccgccg cgagcaccag ggccgccacc gccgcgccgg
    18001 cgacgatccc cacgtcccgc cacatggtgc cggtcggttc ggcgtgcgcg ccgacctcct
    18061 gcagggcctc gaccgcgtac gacaggggca gcgcgtcgct gaccgcctgg agccagccgg
    18121 ccatctggcc gcgcggcacg aagagcccgc agagcagcag ctgcggggcg accacgaccg
    18181 gcatgaactg gaccgcctgg aactcggtgc gggcgaaggc gctgcagaac agcccgagcg
    18241 ccacggccag cacggcgttc agcgccgcga ccaggatgac cagcccggcg ctgccggcgg
    18301 tctccatccc gagcagccag tacgccacgc cggcggcgat ggccgcctgc accgccccgg
    18361 ccagcccgaa cgcgatgccg tagccgaaga gcaggtcgag cttgtgcagc ggcgtggtga
    18421 gcagccgttc cagcgtgccg gtggtgcgct cgcgcagcat cgcgatgctg gtcaccagga
    18481 acatcacgat gaacgggaag aagcccagca tgatcagggc gatccggtcg aaggtcgacg
    18541 gctgcccggg ggcggtgggc aggtcggcgt acatgtagta gaccagggtc agcagcaccg
    18601 tgggcaccac caccagcagc gccaccgtgc gcttgtcgtg ccgcagctgg cgcaggatgc
    18661 gcccgatggt gacggtcaga atccgcgcat tcacgatgcc tcctccgttc gcgactgcgg
    18721 ggctcgcagg cccggctcac tcctcgcgct cacgatgcct cctccgttcg cgactgcggg
    18781 gctcgcaggc ccggctcact cctcgcgctc acgatgcctc ctcggttcgc gactgcgggg
    18841 ctcgcaggcc cggctcactc ctcgcgctca cgatgcctcc tcggttcgcg actgcggggc
    18901 tcgcaggccc ggctcactcc tcgcgctcac gatgcctcct cggttcgcga ctgcggcgct
    18961 cgcaggcccg gctcactcct cgcgctcacg atgcctcctt gccggcgggc tgctggcccg
    19021 cctcgctcga ccggatcaac cgcaggaacg actcctccag gtcgtcgacc ccggtgcgct
    19081 cccggatcgc gtcgggagtg tcgtcggcga ccagccggcc ctcccggatc agcagcagcc
    19141 ggtcgcaccg ggccgcctcg tccatcacgt ggctggacac cagcagcgtc gtgccggccg
    19201 ccgccatctc gtggaaccgg ccccacaggt cggcccgcag caccgggtcc tggccgaccg
    19261 tcggctcgtc gaggatgacc agctcggggt cgccgaccag ggcgcaggcc agcgaggctc
    19321 ggctgcgctg cccgccggag agggtgccga ccagctgggt ggccgcgtcg gccagcccga
    19381 cgtcggcgac cgcccgatcg gcgtcggccc cgtgccggcc ctgcaacgcc gcgaagtagc
    19441 gggcgttctc ccggacggtc aggtcggcgt agacgctggg cgcctgggtc aggtagccga
    19501 cccggtggcg caggtcggcc gagccggccg gccggccgag cacggtgacc gtgcccgagt
    19561 cgatcacctg gacccccacc accgcccgca tcagggtggt cttgccgctg ccgctgggcc
    19621 cgagcagccc ggtcaccgag ccccggggga cggtgcagtc gatgccgtgc agcacccttc
    19681 gccggccccg gtcgacgacc aggtcgcgga ccgtgatcgc gtcctccacc gcccacctcc
    19741 aaaactcatc agctgttgaa ctcaacgcta gatgagatac ccggaccggc gcaatggttg
    19801 acttcgagtg ctctcgaact ggaagcctgg gtggcgtgga catcagcacg caggaaccgg
    19861 ccctctccgt gggcgaggcg gcggcccggg tcggcctgac cacctacacg ctgcgctggt
    19921 acgagcagga ggggctggtc gccccggtcg gtcgggactc ggcggggcgc cgccgctaca
    19981 ccgagtccga cctggactgg ctgctcctgc tcacccggct gcgccgcacc gggatgccgg
    20041 tgcgcgacat gcgccggtac gccgaactgg cccgccaggg cgaccgcacg ctcggcgccc
    20101 ggcgggcgct gttcgaggcg caccgggccc gggtgctggc ccggatggcc gaactggagg
    20161 aggacctgaa ggtgctcaac tacaagatcg acctctaccg ccgagccgag gagggccgat
    20221 gatccgtcga cggatggggg ccaccggccc cgaggtctcg gccatcgggc tgggctgcat
    20281 ggggatgagc ttcgcctacg gcggccgcga cgacgcggaa tccacccgta ccctgcaccg
    20341 ggccctggac ctgggcgtca accacctgga caccgccgac atgtacggcg ccggcgccaa
    20401 cgagcggctg ctctccccgg tggtgcgggc ccgccgcgac gaggtcttcc tggccaccaa
    20461 gttcggcaat cgcaccagcg gcgacagctt cggcggcacc ggcacccccg gcgcgtacgt
    20521 cgacagcagc gccgcctggg cccgggaggc ctgcgacgcc tcactgggcc ggctcggggt
    20581 ggacaccatc gacctgtact acctgcaccg gcgcgacccg cgcacgccga tcgaggagac
    20641 cgtcggcgcg ctggccgagc tggtcgaggc cggcaaggtc cgcctgatcg ggctcagcga
    20701 ggtgagcccg gcgacgctgc gggcggcgca cgcggtgcac ccggtgaccg cggtgcagat
    20761 ggagtactcg ctgttcaccc gggacgtcga gggggagatg ctggacacct gccgggagct
    20821 gggggtggcg ctggtggcgt actccccggt cgggcgaggg ctgctcaccg gggcgatcag
    20881 cgggcgcgac cagctcgccg ccgacgactg gcgggccggc gtgccgcgct tcgccgaggg
    20941 aa
//
