LOCUS       NZ_LT607410            21068 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Micromonospora purpureochromogenes strain DSM 43821 chromosome I.
ACCESSION   NZ_LT607410
VERSION     NZ_LT607410.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora purpureochromogenes
  ORGANISM  Micromonospora purpureochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091515.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,188
            CDSs (total)                      :: 6,117
            Genes (coding)                    :: 5,981
            CDSs (with protein)               :: 5,981
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 48 of 136
            Pseudo Genes (incomplete)         :: 97 of 136
            Pseudo Genes (internal stop)      :: 4 of 136
            Pseudo Genes (multiple problems)  :: 12 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2137324
            Orig. end                         :: 2158392
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            964..2139
                     /locus_tag="GA0074696_RS10050"
                     /old_locus_tag="GA0074696_2018"
     CDS             964..2139
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463814.1"
                     /locus_tag="GA0074696_RS10050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2018"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_172894597.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-24, bitscore:
                     85.5, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.6e-30,
                     bitscore: 103.0, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGYEFMGAAHSQAWRTVNRVFELPARVRMARICGRDAGKVAAAA
                     DRLGWDAYSTDWRELVASDDIDVVDICTPGDSHAEIALAALAAGKHVICEKPLANTVAE
                     AREMTAAAATARAAGVRSMCGFNYRRVPAVALMRQLVAEGRLGVLRHVRAAYLQDWIVD
                     PQFPLVWRLQKDRAGSGALGDIGAHIIDLTQYVTGQRITGVSAVTETFVKERPLPGGSS
                     GLAAQADGNGRATGAVTVDDAAVFVARLDDGALATYEASRFATGRKNALRVEINGSLGT
                     VAFDLERLNELEFYDATRPTAEQGFTRILVTEAEHPYLSAWWPPGHIIGYEHSFTHQMR
                     DFVEAVATGVDPTPSFADALQVQLVLDAVTRSAELGSRWTEVEPALAALAV"
     gene            2651..3799
                     /locus_tag="GA0074696_RS10055"
                     /old_locus_tag="GA0074696_2019"
     CDS             2651..3799
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285783.1"
                     /locus_tag="GA0074696_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2019"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_088960844.1"
                     /transl_table=11
                     /translation="MRTGVWLVGARGSVATTSIVGGLALRAGLTAPTGCVTELPALRGP
                     ALPTFADLFFGGHDLATTPLTKRAETLADAGVLPGRLAATLAAELTAVEEDLRPAPTGG
                     TQADRAAAVVADLTAFRRRHRLDRVVVVDVSATEPAARPHPGHADPAALRAALAGPDEV
                     LPPSSLYAYAAVEAGCPYVSFTPSTGLRLPALAELAVARGLPYAGHDGKTGETLVKSVL
                     APMFAMRHLAVRSWSGVNLLGGGDGATLADPAANAAKVSSKQRVLGETLGYLPQGGTRI
                     EYVEELGDFKTAWDLITFTGFLGTGMRMEFSWHGCDSALAAPLVLDLARLTAAAHAAGR
                     VGPLTDLAFFFKDPLGSPTHSLGEQWQRLVEFTGRLHAGAAA"
     gene            3876..4742
                     /locus_tag="GA0074696_RS10060"
                     /old_locus_tag="GA0074696_2020"
     CDS             3876..4742
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475565.1"
                     /locus_tag="GA0074696_RS10060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2020"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_088960845.1"
                     /transl_table=11
                     /translation="MSALGDLAELVRAPAALSVPGDVVAGAAAAGALGPRTAGLAGASV
                     LLYWAGMAANDWADRRLDAVERPERPIPSGRVSPATAFGLAAGLTAAGLGLAAVTGGRR
                     AAAVAIPLAATIWGYDLAAKNTAAGPAVMAACRGLDVLLGATGGRPVRALPAALTVAAH
                     TVTVTVLSRREVAGADTSLPLRTLAGTALVAIVAARPSTAPAARPAAALPVALAGWYAA
                     RYGGAQARVAADPSAGRVRAAVGAGITGLPALQGALTARAGAGLLGLAVAAAAPLGRRL
                     ARKVSPT"
     misc_feature    complement(3895..3909)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    4155..4157
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4739..5755
                     /locus_tag="GA0074696_RS10065"
                     /old_locus_tag="GA0074696_2021"
     CDS             4739..5755
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072426.1"
                     /locus_tag="GA0074696_RS10065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2021"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_088960846.1"
                     /transl_table=11
                     /translation="MTTPRPHPPAPRPTPDPVGREHPAGAGPRFGYGTNGFANHRLEDA
                     LAVIAELGYQGVALTLDHGHLDPFAPGLARRVDEVARRLDSLGLAVVVETGARYLLDPW
                     HKHAPTLLHDEPARRIDFLTRAVRIGADLGAEAVSCWAGVRPDAVPPAVAWDRLVAGCA
                     AVLDAADRAGVALGFEPEPGMLVEDIAGWRRLRQALGDPARFGITLDIGHCRCLEPRPV
                     PECVHEVAAHLVNVQIDDMRRGVHEHLEFGAGEIDFPPVLRALADAGYRGLVAVELPRH
                     SHAAPTVAARSLDFLRAAGPSTDHPDAPFALLPRTQRRTSDIRTPAVAGGEAEQRTG"
     gene            5817..6416
                     /locus_tag="GA0074696_RS10070"
                     /old_locus_tag="GA0074696_2022"
     CDS             5817..6416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072425.1"
                     /locus_tag="GA0074696_RS10070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2022"
                     /product="EboA domain-containing protein"
                     /protein_id="WP_088960847.1"
                     /transl_table=11
                     /translation="MTPDRLRAALEGVPDPDWLAAALRRVAAEPATIARFFPAAGRHCG
                     RSDLAGAPGWTADEAARALLLTALPADHATHAEALYRHGDAAEKRAVLKALPLLPVGAA
                     GVPLLHDAIRTNDTRLVAAALGPYARHLDPASWRQAVLKCVFAGVPLAGVADLERRADG
                     ELAAMLAALAAERHAAGRELPADATDLLDRLTIREA"
     gene            6417..7271
                     /locus_tag="GA0074696_RS10075"
                     /old_locus_tag="GA0074696_2023"
     CDS             6417..7271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475568.1"
                     /locus_tag="GA0074696_RS10075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2023"
                     /product="TatD family hydrolase"
                     /protein_id="WP_088960848.1"
                     /transl_table=11
                     /translation="MRIFDPHIHMTSRTTDDYERMAAAGVRAVVEPAFWLGQPRTSPAS
                     FADYFDSLIGWEPFRAGQFGVRHHATVALNPKEANDSRCRPVLDLLPRYLEKDTVVAVG
                     EIGYDSMTPQEDEAFAAQLALAVAHDLPALVHTPHRDKARGVERSLAVVAESGIDPGRV
                     VLDHLNEVTVKLVRDTGCWLGFSIYPDTKMSPPRMVELLRAYGPDRVLVNSAADWGRSD
                     PLLTRATGEAMLLAGFTDDDVDRVLWRNPVEFYGQSGRLDLTDLDAVSAGTFAGNSILR
                     GGD"
     gene            7271..8479
                     /gene="eboE"
                     /locus_tag="GA0074696_RS10080"
                     /old_locus_tag="GA0074696_2024"
     CDS             7271..8479
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463801.1"
                     /locus_tag="GA0074696_RS10080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2024"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_088960849.1"
                     /transl_table=11
                     /translation="MRLRHADGSTVHLGYCTNVHPAEDAVGILAQLQTHAEPVREALGA
                     DLLGLGLWLAAPVAAELAADPAARRRLRAELTRRGLEVVTLNGFPYAAFQAPVVKGAVY
                     RPDWTTDARLRYTLDLALILADLLPDDAARGSVSTLPLAWRQPWDTARADAARRRLDDL
                     AAGLAAIERDTGRPVRVGFEPEPGCVVERTGQAVTALAGVDTDRLGVCLDLAHLACAWE
                     EPAEALARLRAAGIPVVKVQVSAALEAAHPPTAADALARWVEPRFLHQTRAAGTAHAAD
                     PADPAYAADDLDGALAGRPPGPWRVHYHVPLHAPPEPPLTSTVPVLRTALAELFAGPAA
                     GCDHLDVETYTWGVLPAARRPRTDAELAAGIAAELAFARDELVALGLTPAGSPVPTTGG
                     VRR"
     gene            8517..10004
                     /locus_tag="GA0074696_RS10085"
                     /old_locus_tag="GA0074696_2025"
     CDS             8517..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475570.1"
                     /locus_tag="GA0074696_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2025"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_088960850.1"
                     /transl_table=11
                     /translation="MSRRLVVLDVVGLTPRLLAHMPRLRAVADEGFVAGLGTVLPAVTC
                     SAQATLLTGELPAGHGIVGNGWYFRDLGEVLLWRQHHALVGGEKLWQAARRAEPGYTVA
                     NVCWWYAMGADVNWTVTPRPVYHADGRKEPDCWTDPPELHDTLTDLGTFPLFTYWGPGA
                     GLPSSAWICRAAERILADHAPDLTLVYVPHLDYDLQRFGPSSPRAAAAAAELDAVLGPL
                     LDAARARDATVVALSEYGITDVSRPVDVNRLLRAEGLLRVYTQAGMEYLDPWTSRAFAV
                     ADHQVAHVYVRDPADVAAVAKLCAGLPGVAEVLDADGKAAAGLDHPRAGELVLVAEPDA
                     WFTYYYWLDDARAPDFARLVEIHRKPGYDPAELFFDPAAPGAAKRRAAVALARKKLGMR
                     YLMSVVGLDAGARAVRGSHGRLPADPADAPVLLCSDPAAARDRLAATEVKALLLELAGL
                     APPASPAGAVPSPAAVASSGGRPPGPAGPTPGPGERR"
     gene            10001..11068
                     /locus_tag="GA0074696_RS10090"
                     /old_locus_tag="GA0074696_2026"
     CDS             10001..11068
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735336.1"
                     /locus_tag="GA0074696_RS10090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2026"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_088960851.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.5e-44, bitscore:
                     148.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTAPPTDTSGLRARFDAELVAFLDRQGPDWPDGAPRGIFAALH
                     RFVLAGGKRLRPLFCYWGWRGAGGGDDRPIVVAAAALELFHAFALIHDDILDGSDRRRG
                     APSVHRLFADLHTRSAWRGDPEAYGRNTALLCGDLCAAWSDQMFHECGLSTAQVCRGYA
                     VFARMRTEVIAGEYLDLVSGVGDGSVASALTVIRMKAARYTVTRPLQIGAALAGAEPEL
                     VTALTDFGDPLGDAFQLRDDVLGVFGDPAVTGKSVLDDLREGKPTVMMALARDAADRAQ
                     SARLRDLFGNPDLDADGAAELRAIIEATGAREQIERLILLRADAARAALDRLPLAEPAL
                     AALAALADQAVHRRR"
     misc_feature    11119..11133
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.4"
                     /tool="antismash"
     misc_feature    11133..11146
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    complement(11165..11179)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.92"
                     /tool="antismash"
     misc_feature    11212..11229
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            11408..14275
                     /locus_tag="GA0074696_RS10095"
                     /old_locus_tag="GA0074696_2027"
     CDS             11408..14275
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463796.1"
                     /locus_tag="GA0074696_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2027"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_088960852.1"
                     /transl_table=11
                     /translation="MSMKDAPTHRSPRWSSAASALLLVAAVGTVGITAGPTALGGPAPA
                     AAHVIIATDFQQVELARGVAETGEPMSLAVLPDRSVLHTARNGTLRRTDANGTTSVIGT
                     LSVYTHDEEGLQGVGVDPNFATNRHIYLYYAPPLSTPAGDAPATGSDFSAWQGVNRLSR
                     FTLNADFTVNQASKVDVLDVPADRGLCCHVGGDIDFDAAGNLYLSTGDDTNPFDSAGYA
                     PLDERTNRNPGYDAQRSAGNTNDLRGKILRIKVNANGTYSIPSGNLFPVGTARTRPEIY
                     AMGFRNPFRMSVDKATGIVYVGDYGPDAGTTSATRGPSGQVEFNRVTSPGNYGWPYCTG
                     TNTSTETYNEWDFATGTGGAKYNCTGGPTNNSFRNTGQSTLPAARPAWIRYGGDAGSPP
                     EFGGGSESPMGGPVYRYNASSTSTTKFPQSFDGQFFATEFGRGWIKPIHVNADGSRGTI
                     DSFPWTGKQVMDSAFGPDGAYYVLDYGTGYFNGDANSALYRFDHIGGGNRAPTARATAD
                     KTSGAAPLAVNFSSAGSSDPEGGALAYAWNFGDGTTSTAANPAKTYTANGTYTATLTVK
                     DPQNATGSASVVISVGNTAPTVTINSPGNGKLFSYGDTVPFSITVTDPEDGTIDCTKVK
                     MTYVLGHDQHGHQITSKTGCSGSIAIPVDGEHDDAANIFAIFDAEYTDAGGLTTHTQHT
                     LQPRHRQAEHFKTSSGINTFDKATAEGGKTVGDINNGDWIAFQPYQLGDVTSFSARVSS
                     AGTGGTLQVRAGSATGTVLGSATVPVTGAWDSFTTVTGAISGAPAGTTTLYLTFAGSGT
                     GALYDVDSFTFTTGATVRTGPVVGLAGKCLDVRNAATADGTQIQLYTCNGTAAQTWTVT
                     PNSTIKALGKCLDVSGGGSADGTKIQLWTCNGSGAQNWSAQADGTVRNPQSGKCLDVSG
                     NNSADSTPVHLWTCTGAANQKWTLP"
     gene            14350..16458
                     /locus_tag="GA0074696_RS10100"
                     /old_locus_tag="GA0074696_2028"
     CDS             14350..16458
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463794.1"
                     /locus_tag="GA0074696_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2028"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_088960853.1"
                     /transl_table=11
                     /translation="MRRLLRPVLGAATAVLAVIACTAPATPASAADAPYDVLVFSKTAG
                     FRHDSIAVGTQAIRDLGAANSFTVTATEDAAAFTTGNLAQYEAVVFLNTTGDVLNASQQ
                     TAFESYIGSGGGYVGVHAAADTEYGWSFYGNLVGAYFASHPAIQQANVKVENRAHPASA
                     HLPQTWTRTDEWYNYQTNARSTARVLATLDESSYSGGGMGADHPHSWCKTYSGGRSFYT
                     GGGHTQASYAEPAFRAHLLGGIRYAAGRAKADCRPETGYTTLYNGSTTGWSQAGPGSFT
                     NADATLTSVGGMGLYWYSAKQFTNYSLKLDWRLAGDDNSGVFIGFPPSTDPWSAVNNGY
                     EIQIDATDAVDRTTGAVYTFKSADIAARDAALNPPGEWNTYELLVEGERLQVFLNGVKI
                     NDFTNTNPVRSLAGHIGLQNHGTGDDASFRNVRIKELGSTPPGGNTTIQAEAFSSASGV
                     TPFTKAGANGGQTLGYIDPGDWSAYNGVDLTGVTSFKARVVSGGPGGTIGVRTGSTTGT
                     VLGSVAVPNTGSWTTYADVTTALTGVPSGTQNLYLTYTGTGTGLFDVDDFTLVRGGATG
                     GTGPIKGLAGKCLDVRSSGTADGTQIQLYTCNGTAAQTWTVAPNSTIRALGKCLDVSGG
                     GSADGTKIQLWTCNGSGAQNWSAQADGSLRNPQSGKCLDVSGNNSADSTPVQLWTCNGA
                     ANQKWTLP"
     gene            16572..17519
                     /locus_tag="GA0074696_RS10105"
                     /old_locus_tag="GA0074696_2029"
     CDS             16572..17519
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="GA0074696_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2029"
                     /product="sensor histidine kinase"
                     /protein_id="WP_088960854.1"
                     /transl_table=11
                     /translation="MGRLAEWRRIARAHPAVTDALLAAGLFVASLLPVNPPGAPLSLAA
                     VLLAAIGSGALAVRRRHPLPVLALTTVSVVLAQLAGVARGPMVLTVAIAAYTVASRAER
                     RTAAVAGLVGALAVGAAAIATLGVSGLDPAVVVLLLWFGVAVAFGDAVRSRRAYVAVLA
                     ERARRAEQTVRPEETGAPTDPAPSLNRLDALVEGFSTGQPVRWTVAGQPRPLPTEVDVA
                     AYRIIQESLTNAHRHAPGAAVAVRLRYDPDGVAIEVRDVGAETSPSPGPSAGLGLLGMR
                     ERVEAVGGTFTAGPRPDGGWSVRAELPAAEEQAE"
     gene            17738..18745
                     /locus_tag="GA0074696_RS10110"
                     /old_locus_tag="GA0074696_2030"
     CDS             17738..18745
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463784.1"
                     /locus_tag="GA0074696_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2030"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_088960855.1"
                     /transl_table=11
                     /translation="MARPITLFTGQWADLPFDEVCRLAAEWGYDGLEIACWGDHFEVDK
                     ALADDSYVERKRETLAKHHLSVHAISNHLVGQAVCDHPIDERHQGILPARIWGDGEPEG
                     VRRRAAEEMKDTARAAAKLGVKTVVGFTGSSIWHTLAMFPPVPPEMIERGYRDFADRWN
                     PILDVFDSVGVRFAHEVHPSEIAYDYWTTRRALAAIGHRPAFGLNWDPSHFVWQELDPV
                     NFILEFADRIYHVDCKDAKVRTGDGRRGRLSSHLPWADLRRGWDFVSTGHGDVPWEDCF
                     RALNAIGYDGPISIEWEDAGMDRLVGAPEALQFVRRLAFDAPAAAFDAAFSSKD"
     gene            complement(18851..20035)
                     /locus_tag="GA0074696_RS10115"
                     /old_locus_tag="GA0074696_2031"
     CDS             complement(18851..20035)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287897.1"
                     /locus_tag="GA0074696_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_2031"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_088960856.1"
                     /transl_table=11
                     /translation="MVPVRPENAYQARLLRMLRDDGPRSRVELGDAVGLSRSRLIAEVD
                     RLVELGLVETAGPAASRGGRRSSLLRLAGTVRFAGVVIGTHRLTVAVTDGELNVLAELR
                     EPADVRSGPGPVVARAAELVGKLRAELGLAQLTGVGVGLPGPVAFREGTPIAPGALPGW
                     HGFPVRDTLGAELGCPTLVDNDANVMALGEQHAGIGRTFDDFLYVKLGTAIGCGLVLRG
                     APHRGATSGAGDIAHLRLADDGPGCACGEAGCLEAYCGEAGLVAAALDAARSGRSPALA
                     DRLATTGTLTMADVAGAAAGGDPVVQAVVRDAARRLGRVLVGLVSFVNPGIVIIGGAPD
                     GLGHTLLAEIRAVVYRRSAPLTTGTMPIVLSDLGERAGVVGAARLISERAFAAE"
     misc_feature    complement(20309..20323)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 caacgccgac ccgggcaaga aggtggtcgt cggcttctcc gccccggccg ccgaccacgg
       61 ctggatcgcc gccatcacca acaacgccaa ggcgcaggcc caggcgtact cggacgtcga
      121 gttcaagtcc gtcgaggccg gcgcggacgc ggcggcgcag cgggcggcgc tgtccaccct
      181 gatctcgcag aagcccgacg tcatcgtgct gctgccgcac gacggcaagg aactcaacgc
      241 cttcggcctg gaggcgatga aggccggcat cccggtggtc aacctggacc gggccttccc
      301 cgacgcgcgc gcctaccggc tgcagatcaa gggcgacaac tacggcatgg gggtggccgc
      361 ggccacctac atcgtcgagc agctcaaggc caagggcgtg agcaacccgg tcatcggcga
      421 gatccccggc atcgactcgc tggagctgac ccaggagcgc tcgaagggct tcgccgacac
      481 gctcgccgcg aacgggctga gggtggccaa ccggcgtccg gcggagttca ccgccgactc
      541 cggtcagcag gccgccaccg gcctgttcca ggcgctgccg aagctcgacg cgctctggaa
      601 ccacgacgac gaccagggca tcggcgttct cgcggcggtc aaccaggcca accgcaagga
      661 gttcttcatg gtcggcggcg ccggctcgaa gaaggcgatg gaggacatcc aggccgacaa
      721 cacggtgctc aaggccaccg tcacctacag cccctcgatg gcctcctcgg ccatctccct
      781 ggcccgcctg atcggccagg gcaagggcat gtccgacctg gtggaactcc aggtgcccaa
      841 ggagatcgtg ctcgcctccg agacgatcac caaggagaac gcgagcaact acctcaagct
      901 cgggttctga cacacggggg gagacccacc ttgtccacac agcacagtga actgcgggtc
      961 ggcatggtcg gctacgagtt catgggcgcc gcgcactcgc aggcgtggcg caccgtgaac
     1021 cgggtgttcg agctgccggc gcgggtccgg atggcgagga tctgcggccg ggacgcgggg
     1081 aaggtcgccg ccgcggccga ccggctcggc tgggacgcgt acagcaccga ctggcgtgag
     1141 ctggtcgcct cggacgacat cgacgtggtc gacatctgca cgcccgggga cagccacgcc
     1201 gagatcgcgc tcgccgcgct cgccgccggc aagcacgtca tctgcgagaa gccgctggcc
     1261 aacacggtgg ccgaggcccg ggagatgacc gccgcggcgg ccaccgcccg ggccgcgggg
     1321 gtacggtcga tgtgcgggtt caactaccgc cgggtgcccg cggtcgccct gatgcggcag
     1381 ctcgtcgccg agggccggct cggggtgctg cggcacgtcc gggcggcgta cctgcaggac
     1441 tggatcgtcg acccgcagtt cccgctggtg tggcggttgc agaaggacag ggcgggctcc
     1501 ggcgcgctcg gtgacatcgg cgcgcacatc atcgacctga cccagtacgt cacgggccag
     1561 cggatcaccg gggtcagcgc ggtgaccgag acgttcgtca aggaacggcc gttgccgggc
     1621 gggtcgagcg gcctggccgc gcaggccgac ggcaacggcc gggccaccgg cgcggtcacc
     1681 gtcgacgacg cggcggtctt cgtcgcccgg ctggacgacg gggcgctggc cacgtacgag
     1741 gcgagccggt tcgccaccgg tcgcaagaac gccctccggg tggagatcaa cgggtcgctc
     1801 gggaccgtcg ccttcgacct ggaacgcctc aacgagctgg agttctacga cgccacccgg
     1861 cccacggccg agcagggctt cacccgcatc ctggtgaccg aggcggagca tccgtacctg
     1921 tcggcctggt ggccgccggg gcacatcatc ggctacgagc actccttcac ccaccagatg
     1981 cgcgacttcg tcgaggcggt cgcgaccggc gtcgacccga cgccctcctt cgccgacgcg
     2041 ttgcaggtcc agctggtgct ggacgcggtg acccggtcgg cggagctggg ctcccggtgg
     2101 acggaggtgg agcccgcgct cgccgcgctc gccgtctgac caggccacct ccggcgccga
     2161 ccggcgagga cccgaccgcg gttgcgcccc gcggacggga gaggggatcg gcaccggagg
     2221 gcgtgccgcc ccggccacca cggccggtgg cgcacgcgta cgacggtcgt ccggtgcggc
     2281 cggaccggga ttccccggcc gcaccggagg accgccacca tcgtcccggc gacccgcagc
     2341 acgcccggcc accaccggcc gggcccgggc cgccaccacc acacgtccgg tcgcggggcg
     2401 cgccgtcgcc cgtcgaccgg atccggggag gcagggccga gacgccgacc gaccctgcct
     2461 gccagccccg tccgcacgcc gtgcggggta ccgggtccgg cgtcgcgccg ccgacgtcgc
     2521 cgccgcagcc cggtcccgcc ccggacgtcc gggcggacgg ggccccggcg gaccggtatc
     2581 tttcccgcga accatttgat attgatgtag ctagatgcaa ggggcggttc ctccggacgg
     2641 aaggagcacc atgcgtacgg gtgtctggct ggtgggggcg cgcggctcgg tcgcgaccac
     2701 cagcatcgtc ggcggtctcg ccctgcgggc cggactcacc gcgccgaccg gttgcgtcac
     2761 cgaactgccc gcgctgcgcg ggccggccct gcccaccttc gccgacctgt tcttcggcgg
     2821 ccacgacctg gccaccaccc cgctgaccaa gcgggccgag acgctggccg acgcgggcgt
     2881 gctgcccggc cggctggcgg ccaccctcgc cgccgagctg accgccgtcg aggaggacct
     2941 gcgaccggcc cccaccggcg gcacccaggc cgaccgggcc gccgccgtcg tcgccgacct
     3001 caccgcgttc cgccggcggc accgactgga ccgggtggtg gtggtcgacg tctccgccac
     3061 cgaaccggcc gcccggccgc accccgggca cgccgacccg gccgccctgc gggccgcgct
     3121 cgccggcccc gacgaggtgc tgccgcccag ctcgctctac gcgtacgccg ccgtcgaggc
     3181 cggctgcccg tacgtgtcct tcaccccgtc caccgggctg cggctgccgg cgctggccga
     3241 gttggccgtc gcgcgcggcc tgccgtacgc cgggcacgac ggcaagaccg gggagaccct
     3301 ggtcaagtcg gtgctcgcgc cgatgttcgc gatgcggcac ctggccgtgc gctcctggtc
     3361 cggggtcaac ctgctcggcg gtggcgacgg cgccaccctc gccgacccgg ccgccaacgc
     3421 cgccaaggtg agcagcaagc agcgcgtcct cggcgagacc ctcggctacc tgccacaggg
     3481 cggcacccgc atcgagtacg tcgaggagct gggcgacttc aagaccgcct gggacctgat
     3541 caccttcacc ggcttcctcg gcaccggcat gcggatggag ttcagctggc acggctgtga
     3601 ctccgcgctc gccgccccgc tcgtgctcga cctggcccgg ctcaccgccg ccgcgcacgc
     3661 cgccggccgg gtcggcccgc tgaccgacct ggcgttcttc ttcaaggacc cgctcggctc
     3721 acccacccat tcgctgggcg agcagtggca gcggctggtc gagttcaccg ggcggctgca
     3781 cgccggggcc gcggcatgag cgagcgcagc gagcgaatca ttcagcgcag cgcggtggag
     3841 cctcatggcg tcgccgaccg aagggaggcg acggcgtgag cgcgctgggc gacctggccg
     3901 agctggtccg ggcgccggcc gcgctctccg taccgggcga cgtggtcgcc ggcgccgccg
     3961 cggccggggc gctcggtccg cgtaccgccg ggctggccgg cgcgtcggtg ctgctgtact
     4021 gggccgggat ggccgccaac gactgggccg accgccggct ggacgccgtc gaacgccccg
     4081 agcggccgat ccccagcggc cgggtctcgc ccgcgaccgc gttcggtctc gccgccggcc
     4141 tcaccgccgc cggtttaggc ctggccgccg tcacgggcgg ccgccgggcc gccgccgtcg
     4201 cgatcccgct cgccgcgacg atctgggggt acgacctggc ggcgaagaac accgccgccg
     4261 gcccggccgt gatggccgcc tgccgggggt tggacgtgct gctcggcgcg acgggtgggc
     4321 ggccggtccg ggcgctgccg gcggcgctca ccgtcgccgc gcacaccgtc accgtcaccg
     4381 tgctctcccg gcgcgaggtg gccggcgcgg acacctcgct gccgctgcgt accctcgccg
     4441 gcaccgccct ggtcgcgatc gtcgccgccc gcccgtccac ggcccccgcc gcccgccctg
     4501 ccgccgcgct gcccgtcgcg ctggccggct ggtacgccgc ccggtacggc ggggcgcagg
     4561 cccgggtggc ggccgacccg tccgccggcc gggtgcgcgc cgcggtcggc gccgggatca
     4621 ccgggctgcc ggcgttgcag ggcgcgctca ccgcccgggc cggtgccggc ctgctcggcc
     4681 tggcggtggc ggccgccgcg ccgctgggcc gccggctggc ccgcaaggtc tcgccgacat
     4741 gaccaccccg cgaccccacc cgccggcccc gcggccgacc cctgacccgg tcggccggga
     4801 gcacccggcc ggggcggggc cgcggttcgg ctacgggacc aacggcttcg ccaaccaccg
     4861 gttggaggac gccctcgcgg tcatcgccga gctgggctac cagggcgtcg cgctcaccct
     4921 cgaccacggc cacctggacc cgttcgcgcc cgggctggcc cgccgggtcg acgaggtggc
     4981 ccgccgactg gactcgctcg gcctcgccgt ggtcgtcgag accggggccc gctacctgct
     5041 cgacccctgg cacaagcacg cgccgacgct gctgcacgac gaaccggccc gccggatcga
     5101 cttcctgacg cgggcggtcc ggatcggcgc cgacctcggc gcggaggcgg tctcctgctg
     5161 ggccggcgta cgcccggacg ccgtaccgcc ggccgtcgcc tgggaccggc tggtcgcggg
     5221 ctgcgcggcc gtgctcgacg ccgcggaccg cgccggggtg gccctcggct tcgagccgga
     5281 acccgggatg ctcgtcgagg acatcgccgg ctggcggcgg ctccggcagg ccctcggcga
     5341 cccggcccgc ttcggcatca ccctcgacat cggacactgc cgctgcctgg agccgcgccc
     5401 ggtgcccgag tgcgtccacg aggtggccgc gcacctggtc aacgtgcaga tcgacgacat
     5461 gcgtcggggc gtgcacgaac acctggagtt cggcgccggt gagatcgact tcccgccggt
     5521 gctgcgcgcc ctcgccgatg ccggctaccg ggggctggtg gcggtggagc tgccccggca
     5581 ctcgcacgcc gcacccaccg tcgcagcccg gtcgctggac tttctacgcg ccgccggacc
     5641 gagcacggac cacccggacg cgccctttgc tctgctgccg cggacgcaac gccggacgtc
     5701 cgatatccgg acaccggccg ttgccggggg tgaagcagag caaaggacgg ggtgaggcac
     5761 ccgcccggtg gcacgacggg cggccagaga gcagcagcac gagggaggag agacggatga
     5821 caccggatcg actgcgggcc gcgctcgagg gcgtacccga tcccgactgg ctggcggcgg
     5881 cgctgcgccg cgtcgcggcc gaacccgcga cgatcgcgcg gttcttcccg gccgccggcc
     5941 ggcactgcgg ccggagtgac ctggccggcg cgcccggctg gaccgccgac gaggcggccc
     6001 gcgcgctgct gctcaccgcg ctgcccgccg accacgccac gcacgccgag gcgctgtacc
     6061 ggcacggcga cgccgccgag aagcgggccg tgctcaaggc cctgccgctg ctgcccgtcg
     6121 gcgcggccgg ggtgccgctg ctgcacgacg cgatccgcac caacgacacc cggctggtgg
     6181 ccgccgccct cggcccgtac gcccggcacc tggacccggc gtcctggcgg caggcggtgc
     6241 tcaagtgtgt cttcgccggc gtgccgctgg ccggcgtggc agacctggag cgccgcgccg
     6301 acggcgagct ggccgcgatg ctcgccgcac tcgccgcgga gcgccacgcc gccggccggg
     6361 agctgcccgc cgacgccacc gacctgctcg accggctcac catcagggag gcgtgaatgc
     6421 gcatcttcga cccgcacatc cacatgacgt cgcggaccac cgacgactac gagcggatgg
     6481 ccgccgccgg ggtccgcgcg gtggtggagc cggcgttctg gctggggcag ccccgcacca
     6541 gccccgcctc cttcgccgac tacttcgact cgctgatcgg ctgggagccg ttccgggccg
     6601 ggcagttcgg cgtccggcac cacgccaccg tcgcgctcaa cccgaaggag gccaacgact
     6661 cgcgctgccg gccggtgctc gacctgcttc cgcgctacct ggagaaggac accgtggtgg
     6721 cggtcggcga gatcggctac gactcgatga ccccgcagga ggacgaggcg ttcgccgccc
     6781 agctggccct ggccgtggcg cacgacctgc cggcgctggt gcacaccccg caccgggaca
     6841 aggcccgggg cgtcgagcgc agcctcgcgg tggtcgccga gtccggcatc gaccccggcc
     6901 gggtggtgct ggaccacctc aacgaggtca ccgtcaagct ggtccgggac accggctgct
     6961 ggctgggctt ctccatctac ccggacacca agatgtcccc gccccggatg gtggagctgc
     7021 tgcgggcgta cggcccggac cgggtgctgg tcaactccgc cgccgactgg gggcgctcgg
     7081 acccgctgct gacccgggcc accggcgagg cgatgctgct ggccgggttc accgacgacg
     7141 acgtcgaccg ggtgctctgg cgcaacccgg tggagttcta cgggcagtcc ggccggctcg
     7201 acctgaccga cctggacgcc gtctcggccg gaaccttcgc cggcaactcg atcctgcgcg
     7261 gcggcgactg atgcggctgc ggcacgccga cggcagcacc gtccacctcg gctactgcac
     7321 caatgtgcac cccgccgagg acgccgtcgg catcctcgcc caactgcaga cccacgccga
     7381 gccggtgcgc gaggcgctcg gcgccgacct gctcgggctc ggcctctggc tggccgcgcc
     7441 ggtcgccgcc gagctggccg ccgacccggc cgcccggcgc cggctgcgcg ccgagctgac
     7501 ccgtcggggg ctggaggtgg tcaccctcaa cggcttcccg tacgcggcct tccaggcgcc
     7561 cgtggtcaag ggcgcggtct accggccgga ctggaccacc gacgcccggc tgcgctacac
     7621 cctcgacctg gccctgatcc tggccgacct gctccccgac gacgccgccc ggggctcggt
     7681 ctccaccctg ccgctggcct ggcggcagcc ctgggacacc gcccgcgccg acgccgcccg
     7741 ccgccggctg gacgacctcg cggccgggct cgccgcgatc gaacgggaca ccgggcgccc
     7801 ggtgcgggtc ggcttcgagc cggagccggg ctgcgtggtc gagcgcaccg gccaggcggt
     7861 caccgcactg gccggcgtgg acaccgaccg gctcggcgtc tgcctggacc tggcacacct
     7921 cgcctgcgcc tgggaggagc cggccgaggc gctggcccgg ctgcgcgccg ccgggatccc
     7981 ggtggtcaag gtgcaggtct ccgccgccct ggaggccgcg cacccgccga ccgccgccga
     8041 cgcgctggcc cgctgggtgg agcctcgctt cctgcaccag acccgggccg ccggcaccgc
     8101 ccacgccgcc gacccggccg acccggcgta cgccgccgac gacctggacg gcgcgctggc
     8161 cgggcggccg ccggggccgt ggcgggtgca ctaccacgtg ccgttgcacg ccccgcccga
     8221 accaccgctg acctcgaccg tgccggtgct gcgtaccgcg ctggccgagc tgttcgccgg
     8281 tcccgccgcc ggctgcgacc acctcgacgt cgagacgtac acgtgggggg tgctgccggc
     8341 ggcgcgccgg ccgcgcaccg acgcggagct ggccgccggc atcgccgccg agctggcctt
     8401 cgcccgcgac gagctggtcg cgctcggcct gacaccggcg gggagtcccg tcccgacgac
     8461 cggaggggta cgacgatgag cgagcgagtg gaccatcgac acggcgaggt gccggcatga
     8521 gccgtcgact ggtggtgctg gacgtggtcg gattgacccc tcggctgctg gcgcacatgc
     8581 cccggctgcg cgcggtcgcc gacgaggggt tcgttgccgg cctgggcacg gtgctgcccg
     8641 cggtgacctg ctcggcgcag gcgaccctgc tcaccgggga gctgccggcc gggcacggga
     8701 tcgtgggcaa cggctggtac ttccgcgacc tcggcgaggt gctgctgtgg cggcagcacc
     8761 acgcgctggt cggtggggag aagctctggc aggccgcccg ccgggccgaa ccgggttaca
     8821 cggtggccaa cgtctgctgg tggtacgcga tgggcgcgga cgtgaactgg acggtcaccc
     8881 cccgcccggt ctaccacgcc gacgggcgca aggagccgga ctgctggacg gacccgccgg
     8941 agttgcacga cacgctcacc gacctgggca ccttcccgct cttcacctac tgggggcccg
     9001 gcgccgggct gccctcctcg gcgtggatct gccgggccgc cgagcggatc ctcgccgacc
     9061 acgccccgga cctcaccctg gtctacgtcc cgcacctcga ttacgacctg caacgcttcg
     9121 gcccgtcctc gccccgggcc gccgcggcgg cggcggagct ggacgcggtg ctgggcccgc
     9181 tgctggacgc cgcccgcgcg cgggacgcga ccgtggtggc gctgtcggag tacggcatca
     9241 ccgacgtctc ccgcccggtg gacgtcaacc ggctgctgcg cgccgagggg ctgctgcggg
     9301 tctacaccca ggccgggatg gagtacctgg acccgtggac gtcgcgggcc ttcgccgtgg
     9361 ccgaccacca ggtggcccac gtctacgtcc gcgacccggc cgacgtggcg gcggtggcga
     9421 agctctgcgc cggcctgccc ggggtggcgg aggtgctcga cgccgacggc aaggcggcgg
     9481 ccgggctgga ccatccgcgc gccggtgagc tggtgctggt ggccgagccg gacgcctggt
     9541 tcacgtacta ctactggctc gacgacgccc gcgccccgga cttcgcccgg ctcgtcgaga
     9601 tccaccgcaa acccgggtac gacccggcgg aactcttctt cgacccggcc gcgccggggg
     9661 cggcgaagcg ccgggcggcg gtcgcgctgg cccgcaagaa gctgggcatg cggtacctga
     9721 tgagcgtggt cggcctcgac gccggggcgc gggcggtccg gggctcgcac ggccggctgc
     9781 ccgccgaccc ggcggacgcc ccggtgctgc tctgctccga cccggccgcc gcccgggacc
     9841 ggctcgcggc caccgaggtg aaggcgctgc tgctggagct ggccgggctg gccccgccgg
     9901 cgtcccccgc cggtgcggtg ccgtccccgg ccgccgtggc gtcgtcgggc gggcgaccgc
     9961 ccggtcctgc cggaccgact ccgggaccgg gggagcggcg gtgaccgtca ccgcgccccc
    10021 gaccgacacc agcgggctgc gggcgcgctt cgacgccgaa ctggtggcct tcctggaccg
    10081 gcaggggccg gactggccgg acggggcgcc gcgcggcatc ttcgccgccc tgcaccgctt
    10141 cgtgctggcc ggcggcaagc ggttgcgccc gctgttctgc tactggggct ggcgcggcgc
    10201 cggcggcggt gacgaccgac cgatcgtggt cgccgcggcg gcgctggagc tgttccacgc
    10261 gttcgccctg atccacgacg acatcctcga cggcagcgac cgccgccggg gcgcgccgtc
    10321 ggtgcaccgg ctcttcgccg acctgcacac ccggtccgcc tggcgcggcg acccggaggc
    10381 gtacgggcgc aacaccgcgc tgctctgcgg ggacctctgc gcggcctggt cggaccagat
    10441 gttccacgag tgcgggttga gcaccgcgca ggtctgccgg gggtacgcgg tcttcgcccg
    10501 gatgcggacc gaggtgatcg cgggggagta cctggacctg gtctccggtg tcggggacgg
    10561 ctcggtggcc agcgcgctca ccgtgatccg gatgaaggcc gcccggtaca cggtcacccg
    10621 cccgttgcag atcggcgcgg cgctggccgg cgccgagccg gagctggtca ccgcgctcac
    10681 cgacttcggc gacccgctcg gtgacgcgtt ccagctccgc gacgacgtgc tcggcgtctt
    10741 cggtgacccg gcggtgaccg gcaagtccgt cctggacgac ctgcgtgagg gcaagccgac
    10801 ggtgatgatg gcgctggccc gcgacgccgc cgaccgggcg cagagcgccc ggctgcggga
    10861 cctgttcggc aatcccgacc tggacgccga cggcgcggcc gagctgcgcg cgatcatcga
    10921 ggcgaccggg gcccgggagc agatcgagcg gctgatcctg ctgcgcgcgg acgccgcccg
    10981 ggcggcgctg gaccggctgc cgctggcgga gccggccttg gcggcgctgg ccgcgctggc
    11041 cgaccaggcg gtgcaccgcc ggcgctgaca ccggtgcgcc gccacggccc gccggggcct
    11101 ttcctcgcca tgcccgcgag ctttcagcca atcggacgaa agttcgcttc cacggggcag
    11161 aaggtatgga cagacaaatt cacaaccctt aatgttcgtg gcatcacgaa catgtttcgt
    11221 cgaggtgaac cggcggcgcg gtaacccatc gactggtggc ctccgggcgc gcggtccccc
    11281 gccccgaccg gtggtcacgg ccggtccggc gccgcccgga ccgccctgcc gcatccccgt
    11341 acccggcacc ggcgcgacgg cgcgcgcccc accctggcag tcactcgtca ggaagggaca
    11401 gcacagaatg tccatgaagg acgcacccac ccaccgctcc ccacgatggt cctccgccgc
    11461 gtccgccctg ctcctggtgg cggccgtcgg caccgtcggc atcacggccg gcccgaccgc
    11521 cctcggcggc cccgccccgg ccgccgccca cgtcatcatc gccaccgact tccagcaggt
    11581 cgagctggcc cgcggcgtcg ccgagacggg cgagccgatg tccctggccg tgctgccgga
    11641 ccgctcggtc ctgcacaccg cccgtaacgg caccctgcgg cgcaccgacg ccaacggcac
    11701 cacctcggtg atcggcacgc tgtcggtcta cacccacgac gaggaggggt tgcagggcgt
    11761 cggcgtcgac ccgaacttcg ccaccaaccg gcacatctac ctctactacg ccccgccgct
    11821 gtccaccccc gccggcgacg cgccggccac cggcagcgac ttctccgcct ggcagggcgt
    11881 caaccggctg tcccggttca ccctcaacgc cgacttcacc gtcaaccagg ccagcaaggt
    11941 cgacgtgctg gacgtacccg ccgaccgggg gctgtgctgc cacgtcggcg gcgacatcga
    12001 cttcgacgcc gccggcaacc tctacctgtc caccggcgac gacaccaacc cgttcgactc
    12061 cgccggctac gccccgctcg acgagcggac caaccgcaac cccgggtacg acgcgcagcg
    12121 cagcgccggc aacaccaacg acctgcgcgg caagatcctg cggatcaagg tgaacgccaa
    12181 cgggacgtac tcgatcccgt ccggcaacct cttcccggtc ggcaccgcga ggacccggcc
    12241 cgagatctac gcgatgggct tccgcaaccc gttccggatg agcgtcgaca aggccaccgg
    12301 catcgtctac gtcggcgact acggccccga cgccggcacc acctcggcca cccggggccc
    12361 ctccggccag gtcgagttca accgggtcac ctcgcccggc aactacggct ggccgtactg
    12421 caccggcacc aacaccagca ccgagaccta caacgagtgg gacttcgcca ccggcaccgg
    12481 cggcgccaag tacaactgca ccggcggccc caccaacaac tcgttccgca acaccggcca
    12541 gagcacgctg cccgcggcca ggccggcctg gatccggtac ggcggcgacg ccggcagccc
    12601 gcccgagttc ggcggcggct ccgagtcccc gatgggcggc ccggtctacc gctacaacgc
    12661 gtcgtcgacc tcgaccacca agttcccgca gtccttcgac gggcagttct tcgccaccga
    12721 gttcggccgc ggctggatca agccgatcca cgtcaacgcc gacggctcgc gcggcaccat
    12781 cgacagcttc ccgtggaccg gcaagcaggt gatggactcc gccttcggcc cggacggcgc
    12841 gtactacgtg ctcgactacg gcaccggcta cttcaacggc gacgccaact cggcgctcta
    12901 ccgcttcgac cacatcggcg gcggcaaccg ggcgccgacg gcgagggcga ccgcggacaa
    12961 gacctccggc gccgccccgt tggccgtcaa cttctcctcg gccgggtcgt cggacccgga
    13021 gggcggggcg ctggcgtacg cgtggaactt cggcgacggc accacctcca ccgccgccaa
    13081 cccggcgaag acctacaccg ccaacgggac gtacaccgcc acgctgacgg tgaaggaccc
    13141 gcagaacgcc accggcagcg ccagcgtggt gatcagcgtc ggcaacaccg ccccgaccgt
    13201 gacgatcaac agccccggca acggcaagct cttctcctac ggcgacaccg tgcccttcag
    13261 catcaccgtc accgaccccg aggacggcac gatcgactgc accaaggtca agatgaccta
    13321 cgtgctcggc cacgaccagc acggccacca gatcacctcg aagaccggct gctccggctc
    13381 gatcgccatc ccggtcgacg gtgagcacga cgacgcggcg aacatcttcg ccatcttcga
    13441 cgccgagtac accgacgcgg gcgggctgac cacgcacacc cagcacaccc tccagccccg
    13501 ccaccggcag gccgagcact tcaagacctc gtccggcatc aacaccttcg acaaggcgac
    13561 cgccgagggc ggcaagaccg tcggcgacat caacaacggg gactggatcg ccttccagcc
    13621 gtaccagctt ggcgacgtca cctcgttcag cgcccgggtc tcctcggccg ggacgggcgg
    13681 caccctccag gtccgggccg ggtcggccac cggcacggtg ctcggctccg ccacggtgcc
    13741 ggtcaccggc gcctgggact ccttcaccac ggtcaccggc gcgatctccg gggcgccggc
    13801 gggcaccacg acgctctacc tgacctttgc cgggtcgggc accggggcgc tctacgacgt
    13861 cgactcgttc accttcacca cgggcgcgac ggtgcgcacc gggccggtgg tcgggctcgc
    13921 cggcaagtgc ctggacgtcc gcaacgccgc caccgccgac ggcacccaga tccagctcta
    13981 cacctgcaac ggcaccgcgg cgcagacctg gacggtgacg ccgaactcga cgatcaaggc
    14041 gctgggcaag tgcctggacg tctccggtgg cggctccgcc gacgggacca agatccagct
    14101 ctggacctgc aacggcagcg gcgcgcagaa ctggtccgcc caggccgacg gcacggtgcg
    14161 caacccgcag tccggcaagt gcctcgacgt ctcgggcaac aactccgccg acagcacccc
    14221 ggtgcacctg tggacctgca ccggcgccgc caaccagaag tggaccctgc cgtaaccgag
    14281 tgaacgcgcg ggggccccgc ccggcccgcc ggcccgcccg gggtccccgc ccaccgatag
    14341 gagagcgaca tgcgcagact cctgcgtccc gtcctcggcg cggccaccgc cgtcctcgcc
    14401 gtcatcgcct gcaccgcccc cgccaccccg gcgtccgccg ccgacgcccc gtacgacgtg
    14461 ctggtcttct ccaagaccgc cgggttccgg cacgactcca tcgccgtcgg cacccaggcc
    14521 atccgcgacc tgggcgcggc caacagcttc accgtcaccg ccaccgagga cgccgccgcg
    14581 ttcaccaccg gcaacctggc ccagtacgag gcggtggtct tcctcaacac caccggcgac
    14641 gtgctcaacg ccagccagca gaccgccttc gagtcgtaca tcggctccgg cggcgggtac
    14701 gtcggcgtgc acgccgccgc cgacaccgag tacggctggt cgttctacgg caacctggtc
    14761 ggggcgtact tcgcctcgca cccggccatc cagcaggcca acgtcaaggt ggagaaccgg
    14821 gcgcacccgg ccagcgcgca cctgccgcag acctggaccc gcaccgacga gtggtacaac
    14881 taccagacca acgcccgctc caccgcccgg gtgctggcca ccctggacga gtcgtcgtac
    14941 tccggtggcg ggatgggcgc ggatcatccg cactcctggt gcaagaccta cagcggcggc
    15001 cggtccttct acaccggcgg tgggcacacc caggcgtcgt acgccgaacc ggcgttccgg
    15061 gcccacctgc tcggcggcat ccgctacgcg gccggccgcg ccaaggccga ctgccggccg
    15121 gagaccggct acaccaccct ctacaacggt tccaccaccg gctggtcgca ggccggaccg
    15181 ggcagcttca ccaatgccga cgccacgctc acctcggtcg gcgggatggg cctctactgg
    15241 tacagcgcga agcagttcac caactactcg ctcaagctgg actggcggct cgccggcgac
    15301 gacaactccg gggtcttcat cggcttcccg ccgtcgaccg acccctggtc cgcggtcaac
    15361 aacggctacg agatccagat cgacgccacc gacgcggtcg accgcaccac cggcgcggtc
    15421 tacaccttca agtccgccga catcgccgcc cgggacgcgg cgctgaaccc gccgggcgag
    15481 tggaacacct acgagctgct ggtcgagggc gagcggctcc aggtcttcct caacggcgtg
    15541 aagatcaacg acttcaccaa caccaacccg gtccgttcgc tcgccgggca catcggcctg
    15601 cagaaccacg gcaccggcga cgacgcgtcg ttccgcaacg tccggatcaa ggaactcggc
    15661 tccaccccac cgggcggcaa caccaccatc caggccgagg cgttcagctc ggccagcggg
    15721 gtcaccccgt tcaccaaggc cggcgcgaac ggcgggcaga ccctcggcta catcgacccg
    15781 ggtgactggt cggcgtacaa cggggtggac ctgaccgggg tgacgtcctt caaggcgcgg
    15841 gtcgtctccg gcggtcccgg cggcaccatc ggagtgcgta ccggctccac caccggtacc
    15901 gtcctcggct cggtcgcggt gcccaacacc gggagctgga cgacgtacgc cgacgtcacc
    15961 accgccctga ccggggtgcc gtccggcacc cagaacctgt acctgaccta caccggcacc
    16021 ggcaccgggc tcttcgacgt cgacgacttc accctggtcc ggggcggcgc caccggcggc
    16081 accggaccga tcaagggcct cgccggcaag tgcctggacg tccgcagcag cggcaccgcc
    16141 gacggcacgc agatccagct ctacacctgc aacggcaccg cggcgcagac ctggacggtg
    16201 gcgccgaact cgacgatcag ggcgctgggc aagtgcctgg acgtctccgg tggcggctcc
    16261 gccgacggga ccaagatcca gctctggacc tgcaacggca gcggcgccca gaactggtcg
    16321 gcccaggccg acgggtcgct gcgcaacccg cagtccggca agtgcctgga cgtctcgggc
    16381 aacaactccg ccgacagcac cccggtccag ctctggacct gcaacggcgc cgccaaccag
    16441 aagtggaccc tgccctgacc cactgaccgc gccggccacc gcgccggccc gttcgacacc
    16501 gacaccgccg gggtgccacg caccccggcg gtgccgcgtc cggggccggg cggctgccgt
    16561 accttgaccg catgggacgg ctcgcggagt ggcgccggat cgcgcgggcg cacccggcgg
    16621 tcaccgacgc gctgctggcc gccgggctct tcgtggccag cctgctgccg gtgaacccgc
    16681 ccggggcgcc gctcagcctc gccgccgtgc tgctcgccgc catcggctcc ggggcgctcg
    16741 cggtgcgccg ccgccatccg ctgccggtgc tcgccctgac caccgtcagc gtggtgctcg
    16801 cgcagctcgc cggggtcgcc cgggggccca tggtgctcac cgtggcgatc gccgcgtaca
    16861 ccgtcgccag ccgcgccgaa aggcggaccg ccgccgtggc cggtctggtc ggcgccctcg
    16921 ccgtcggcgc ggcggcgatc gccacgctcg gcgtgtccgg gctggacccg gcggtggtgg
    16981 tgctgctgct ctggttcggc gtcgcggtgg ccttcggcga cgcggtgcgc agccggcggg
    17041 cgtacgtggc ggtgctggcg gagcgggccc ggcgcgccga gcagaccgtg cggccggagg
    17101 agaccggcgc acccaccgac ccggcgccca gcctgaaccg gctggacgcg ctggtcgagg
    17161 ggttcagcac cggccagccg gtgcgctgga cggtggccgg ccagccccgc ccgctgccca
    17221 ccgaggtgga cgtcgcggcg taccggatca tccaggagtc gctgaccaac gcgcaccggc
    17281 acgcgccggg cgcggcggtg gcggtccggc tgcgctacga ccccgacggc gtcgccatcg
    17341 aggtacgcga cgtcggcgcc gagacgtcac cgtcgcccgg accgagcgcc gggctcggcc
    17401 tgctcggcat gcgcgagcgg gtcgaggcgg tcggcggcac cttcaccgcc ggcccccgcc
    17461 cggacggcgg ctggtcggtg cgcgccgagc tgcccgccgc cgaggagcag gccgagtgac
    17521 cttcccccgg tccgtggcgg gcccttccca gtcggtcccg gcggtcctag agtgagggcg
    17581 gcgaccgcga ggtggccggt gacccggcgg gaggcgcaac ccgtcggggc ccaggtgcgt
    17641 gccgcaccca ccggcgaccc gtgaccgctt ccgtaccggt ggcccctcgc cccgcccacg
    17701 ctcaggaatc cccctcacga caggggagac aacgacgatg gcgcgaccga tcacgctctt
    17761 caccggccag tgggccgatc ttccgttcga cgaggtctgc cggctcgccg ccgagtgggg
    17821 ctacgacggg ctggagatcg cctgctgggg cgaccacttc gaggtcgaca aggccctcgc
    17881 cgacgactcg tacgtcgagc gcaagcggga gaccctcgcc aagcaccacc tcagcgtcca
    17941 cgccatctcc aaccacctcg tcgggcaggc ggtctgcgac cacccgatcg acgagcggca
    18001 ccagggcatc ctgccggccc ggatctgggg cgacggcgaa cccgaggggg tacgccggcg
    18061 cgccgccgag gagatgaagg acaccgcccg cgcggcggcg aagctcgggg tgaagacggt
    18121 ggtcgggttc accggctcgt ccatctggca caccctggcg atgttcccgc cggtgccgcc
    18181 ggagatgatc gagcgcggct accgggactt cgccgaccgg tggaacccca tcctcgacgt
    18241 cttcgactcc gtcggggtcc gtttcgccca cgaggtgcac cccagcgaga tcgcctacga
    18301 ctactggacg acccggcggg cgctcgcggc gatcggccac cggccggcgt tcgggctcaa
    18361 ctgggacccg tcgcacttcg tctggcagga gctggacccg gtgaacttca tcctcgagtt
    18421 cgccgaccgg atctaccacg tggactgcaa ggacgcgaag gtacgcaccg gcgacgggcg
    18481 gcgtggccgg ctctcgtccc acctgccctg ggccgacctg cgccggggct gggacttcgt
    18541 ctccaccggc cacggcgacg tgccgtggga ggactgcttc cgggcgctca acgcgatcgg
    18601 ctacgacggg ccgatctcca tcgagtggga ggacgccgga atggaccggc tggtcggcgc
    18661 gccggaggcg ttgcagttcg tccgccggct cgccttcgac gcccccgcgg cggcgttcga
    18721 cgccgcgttc agcagcaagg actgacgcgc ctcggcccga ccgacccctg cccgacctcc
    18781 ccgtgaggcg ggaagtccct ggggtcggtc aggccgccgg gccgcgttcg tggcgccggg
    18841 gccgggccgg tcactcggcg gcgaaggccc gctcgctgat cagccgggcc gcgcccacca
    18901 cgccggcccg ctcgccgagg tcggacagga cgatcggcat cgtgccggtg gtcagcggcg
    18961 ccgaccggcg gtagaccacg gcccggatct cggccagcag ggtgtgcccg aggccgtccg
    19021 gggcgccgcc gatgatcacg atgcccgggt tgacgaagct caccagcccg accagcaccc
    19081 ggcccagccg gcgggcggcg tcgcgcacga cggcctgcac caccgggtcg cctccggccg
    19141 ccgccccggc gacgtccgcc atggtcaggg tgccggtggt ggccagccgg tcggccaggg
    19201 cgggggagcg gcccgaccgc gccgcgtcga gcgccgcggc gaccagcccg gcctcgccgc
    19261 agtacgcctc caggcacccc gcctcgccgc aggcgcagcc cgggccgtcg tcagcgagtc
    19321 gcaggtgggc gatgtcgccg gcgccgctcg tcgcgccccg gtgcggcgcg ccccgcagca
    19381 ccaggccgca gccgatcgcg gtgccgagct tgacgtacag gaagtcgtcg aaggtacggc
    19441 cgatcccggc gtgctgctcg ccgagcgcca tcacgttggc gtcgttgtcg accagcgtcg
    19501 gacagcccag ctcggcaccg agggtgtcgc gcaccggaaa cccgtgccag ccgggcaggg
    19561 caccgggtgc gatcggggtg ccctcccgga aggcgaccgg ccccggcagg ccgacgccga
    19621 cgccggtgag ctgggccagg cccagttcgg cccggagctt gccgacgagt tccgcggccc
    19681 gggcgaccac cggccccgga ccggaccgga cgtctgccgg ctcgcggagc tcggccagca
    19741 cgttcagctc gccgtcggtg acggcgacgg tgagtcggtg cgtgccgatc acgacgccgg
    19801 cgaagcggac cgtaccggcg aggcggagca gcgacgaccg ccggccgccg cgggaggccg
    19861 ccggcccggc ggtctcgacc aggcccagct ccacgaggcg gtccacctcc gcgatcagcc
    19921 tcgaccggga caggcccacc gcgtcgccca gctccacccg cgaccgcggg ccgtcgtcgc
    19981 gcagcattcg cagcagtcgt gcctggtacg cgttctccgg tcggacggga accatcgcca
    20041 ccacctccgg ccggagtctt ccacggcggt gttacgtctg atggcgcgag tggccgcacc
    20101 cggtacgccg cccgggtgcg gccactcgat cgacggtcgg gtccgtcagc cccgcagacc
    20161 cgacatgtgc tggtagctca cctcggcgta gcgcagcgag cggcccgggt cggcgctgcc
    20221 gcccggcgcg ttgtcctgct cccacatcgg gttgtggtag cccttcgcac ccatgttgcc
    20281 gaagaaggtg ccgtagtcga tgtcgccctg gccgagcggc accatctcgt acccgctggt
    20341 ggtgtccggg ttgaacgcgc cgtccttggc gtggaacagc gggaaccgga tcggctgggc
    20401 cgccaccgtg gccagcgggt cgaagacgtc ggtctgcgtc accccgtccg ggtcggtgta
    20461 gctgcggaac cggtgctggg ccacgtgcgc ccagtagatg tccatctcga accagacgta
    20521 ctccgggtcg gtgagcccga tgaagtactc cagcttccgg acgccggagg accgggtggg
    20581 ccggcccagc tcgtccagcg gcccgctgtc gagcaggaag ttgtacgccg cgtcgtggtt
    20641 gtgcgtgtag agcttgagcc cacgggcggc ggccaactgg ccgagggtgt tccaccggtc
    20701 ggccgccgcg tcccagtcgg ccttgtagtt gctgccggtc gggtcgttgc cggtgccgat
    20761 gtgggtcatc cccagcgtct cggcgatgtc gagctgctgc tcgaacgcgg cgagggtggt
    20821 ggggttgatg gtgctcggga tggaggcgtg cgagccgttg gcgcgcagcc cgttgtcgtc
    20881 gaggatcttg cggatctcgg cggcggtgat ctgccggccc aggatggaga cgtgctggtt
    20941 gtagccggcg aactcgacct ccttgtagcc gatctcggcg agccgggcga gcacccgctc
    21001 gaagccgtac ggcactccgg tggcgtccgg tgcggcgccg atccggtccc ggacgctgta
    21061 gaggatga
//
