LOCUS       NZ_LT607410            22138 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Micromonospora purpureochromogenes strain DSM 43821 chromosome I.
ACCESSION   NZ_LT607410
VERSION     NZ_LT607410.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora purpureochromogenes
  ORGANISM  Micromonospora purpureochromogenes
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091515.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 12:12:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,188
            CDSs (total)                      :: 6,117
            Genes (coding)                    :: 5,981
            CDSs (with protein)               :: 5,981
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 48 of 136
            Pseudo Genes (incomplete)         :: 97 of 136
            Pseudo Genes (internal stop)      :: 4 of 136
            Pseudo Genes (multiple problems)  :: 12 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:07:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 351165
            Orig. end                         :: 373303
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22138
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22138
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22138
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12138]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12138
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(23..35)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            41..2382
                     /locus_tag="GA0074696_RS01590"
                     /old_locus_tag="GA0074696_0321"
                     /pseudo=""
     CDS             41..2382
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019870002.1"
                     /locus_tag="GA0074696_RS01590"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0321"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAPPPVGALRDLLHQHHHDLPDTDPERILALVSSGRTAGADTDEL
                     TRLAIAAAAGLTAEEPGYARLAARLLAGRIADETTGQGIDSFSDSVAAAYAEGLLDPGF
                     AGFVATHAAALDALVDHAGDDAFEYFGLRTLHDRYLLRHPRSRAVLERPQHFWLRVATG
                     LSDTVEQAGELYRLMSRLAYLPSSPTLFNAGARHQQLSSCFLVDSPRDELDSIYERYTQ
                     VAKLSKFAGGIGISWSRVRSRGR"
     gene            2385..3370
                     /locus_tag="GA0074696_RS01595"
                     /old_locus_tag="GA0074696_0322"
                     /pseudo=""
     CDS             2385..3370
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018348866.1"
                     /locus_tag="GA0074696_RS01595"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0322"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLDPGMDLTLRPMRYPDFYERFRAAIRNTWTVEEVDLASDVPDL
                     ATLSVGERHLVHRLVAFFATGDSIVANNLVLNLYQHVNAPEARLYLSRQLYEEAVHVQF
                     YLTLLDTYLPDHEERAKAFAAVEHIPSIRDKAEFCFRWIDSIGGLHRLETRAERRAFLL
                     NLICFAAGCSSTAPSPTSTGCARAGCFPGWPPAPTGCSATSRCTWSSPSRWSTPSAPRS
                     RRCSTRRWRMRCGPCWTRR"
     gene            3390..4457
                     /locus_tag="GA0074696_RS01600"
                     /old_locus_tag="GA0074696_0323"
     CDS             3390..4457
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020516710.1"
                     /locus_tag="GA0074696_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0323"
                     /product="DNA glycosylase AlkZ-like family protein"
                     /protein_id="WP_088959443.1"
                     /transl_table=11
                     /translation="MPVHRLDRVDARRIAVRAQLLDAHRPPDLLTVVNRLTFLQLDPTA
                     AVAPSADLVAWTRLGAGYRPDHLRQAVEQDRSMFEHQAMVWPTADLGLHLAEMAAWPPE
                     GSRKHAWLAANATFHRFVLDLLRDSGPLLSRDVPDRSVVPWPSTGWTNNRNVTQLLEIL
                     AARGEIAIADRVGRQRRWDLAERVYPAGTTAVPADEARRMRDERRLRSLGIARASVVGE
                     AGEPAQVEGTAGTWRVDPAALGQPFAGRTALLSPFDRLVHDRKRARELFDFEYVLEMYL
                     PKAKRRWGYFALPVLHHDRLVGKVDATADHRAGVLRVHAIHQDAPFTRAVTAAVGAELD
                     ALASWLGLTEVTRIS"
     gene            complement(4501..4920)
                     /locus_tag="GA0074696_RS01605"
                     /old_locus_tag="GA0074696_0324"
     CDS             complement(4501..4920)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="GA0074696_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0324"
                     /product="ester cyclase"
                     /protein_id="WP_088959444.1"
                     /sec_met_domain="PF07366 (E-value: 3e-32, bitscore: 109.6,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METTETRVVREFMTRVRSGVDPDAAHRLMADRVLAHQVQAEDELT
                     VERTPAQYAAHVRDMLAAYGDFSLRVDELFGAGDRVYARWTQHGRHLGEVDGFPPTGLP
                     VTQVTSAVYRVRDGRIVEYWIQIDRHGLGAQLRRS"
     gene            complement(5160..5786)
                     /gene="bluB"
                     /locus_tag="GA0074696_RS01610"
                     /old_locus_tag="GA0074696_0325"
     CDS             complement(5160..5786)
                     /EC_number="1.13.11.79"
                     /GO_function="GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032363 - FMN catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bluB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074016.1"
                     /locus_tag="GA0074696_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0325"
                     /product="5,6-dimethylbenzimidazole synthase"
                     /protein_id="WP_088959445.1"
                     /sec_met_domain="PF00881 (E-value: 1.9e-27, bitscore: 94.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLYTAIHRRRDVRAEFTGAPVPDDTLHRVLDAAHAAPSVGYSQP
                     WDFVLVRDAGLRRRFHEHVRTERDTFAATLSGEAAARFARIKIDGVLESTLSVVVTYDP
                     SRGGPAVLGRHAIADAGLYSVCLAIQNLWLAATAEGLGVGWVSFYREPFLADLLGIPTG
                     IRPVAWLCVGPVTHLEEVPDLARHGWRQKRPLADALHTDRWAGGR"
     regulatory      complement(5822..6020)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            6156..6917
                     /locus_tag="GA0074696_RS01615"
                     /old_locus_tag="GA0074696_0326"
     CDS             6156..6917
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (8-224). E-value: 6.5e-43. Score:
                     138.7. Matches aSDomain:
                     nrpspksdomains_GA0074696_RS01615_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785442.1"
                     /locus_tag="GA0074696_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0326"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_088964296.1"
                     /transl_table=11
                     /translation="MAVHVTHDGPVTTVILDRAASRNAVDGPTARALADAFRAFEADPE
                     ARVAVLWGAGGTFCSGADLKAIGTPSGNRVEPDGDGPMGPTRISLSKPVVAAISGYAVA
                     GGLELALWCDLRVAESDAVFGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLVLTGRPVP
                     AEEAYAMGLVNRLVPPGEARAEAERLAAEIARHPQTCLRNDRASVLATAGLTEPEALAT
                     ELAYGMRSLNTDAAAGAARFAAGAGRHGTVS"
     aSDomain        6180..6827
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0074696_RS01615_ECH.1"
                     /evalue="6.50E-43"
                     /label="GA0074696_RS01615_ECH.1"
                     /locus_tag="GA0074696_RS01615"
                     /protein_end="224"
                     /protein_start="8"
                     /score="138.7"
                     /tool="antismash"
                     /translation="GPVTTVILDRAASRNAVDGPTARALADAFRAFEADPEARVAVLWG
                     AGGTFCSGADLKAIGTPSGNRVEPDGDGPMGPTRISLSKPVVAAISGYAVAGGLELALW
                     CDLRVAESDAVFGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLVLTGRPVPAEEAYAMG
                     LVNRLVPPGEARAEAERLAAEIARHPQTCLRNDRASVLATAGLTEPEALATEL"
     gene            complement(6910..8394)
                     /locus_tag="GA0074696_RS01620"
                     /old_locus_tag="GA0074696_0327"
     CDS             complement(6910..8394)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454372.1"
                     /locus_tag="GA0074696_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0327"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_088959446.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.8e-47, bitscore:
                     158.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPEVVDVVVVGLGVGGEEVAGRLAEAGLSVVGIERDLVGGECP
                     YWGCIPSKMMIRAANALAEARRVNELAGSAQVQPDWAPVAKRIREEATDTWDDTVAVDR
                     FTGRGGRFLRGSARLDGPGRVRVGDQVIQARHGIVFGTGTRPSVPPIDGLADTPYWTNH
                     QAIEVEELPESLLVLGGGAIGLELAQVFARFGVRVTVVEAADRVLAVEEPESSEVAEKA
                     LRADGVEIRTGVKAERVSHDGATFTVHAGDDAFHAERLLVVTGRRAHLEELGLDSIGVD
                     PGQRYLPVDGQMRVTDGVWAVGDVTGEGAFTHIAMYQAAIVIAGVLDRTRHADSGPDPS
                     GTASVVGGAMGAASAVGGAMTATGPSGAAGTLPRADYRALPRVTFTDPEVGAVGLTEHQ
                     ARQRGINVQVGFAQLSSSARGWIHKAGNDGFIKLVADADQGVLVGATSVGPAGGEVLSA
                     LVVAVHAAVPLSHLRHMIYAYPTFHRAIEDALRDLS"
     gene            8487..9542
                     /locus_tag="GA0074696_RS01625"
                     /old_locus_tag="GA0074696_0328"
     CDS             8487..9542
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473461.1"
                     /locus_tag="GA0074696_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0328"
                     /product="serine hydrolase"
                     /protein_id="WP_088959447.1"
                     /transl_table=11
                     /translation="MPDRFAPVRDCFQDLLATGRETGAGLTIWYDGHPVVDLGADSRGA
                     WRPDTLVNVYSVGKPVAALCLLLLVDRGRLDLDDPVATHWPGFRTPATVRQVLSHTAGL
                     PTFPVARPAEAVADWELLCADLAAADPEWEPGSVAGEHAWTYGHLVGELVRRVDGRSVG
                     RFLAEEIADPWRLDLGFGLGAADQRRCADLSYGDPAWPVRMLGEPGSLRARALSNPPGG
                     LDLAVVNSPLWRGAQVPAVNLHATASALARLYAGLAAGGTLDGVRLFSPELVAEATRVQ
                     YDGPDLVLDRRACWTLGMQREPDGSWGMGGIGGSSAWADPERGYVFGYATAHLADHDRV
                     DELVEVLHSCL"
     gene            complement(10001..10918)
                     /locus_tag="GA0074696_RS01630"
                     /old_locus_tag="GA0074696_0330"
     CDS             complement(10001..10918)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015633.1"
                     /locus_tag="GA0074696_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0330"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_088959448.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.1e-114,
                     bitscore: 378.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-65,
                     bitscore: 220.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTDLTAAYARCQELHRRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEELPPAERAARLDQWSAEFVAGLHGEPVDDPLLPAVLHTIAVFDLDRAD
                     FASFLRSMAMDLTVLSYPTYDDLLDYMEGSAAVIGTMMLPILGSSDPAAAREPARQLGF
                     AFQLTNFIRDVAEDLDRGRTYLPDEDLAKFGVTRDDLLAAKDQARTTPRIRDLIGYEVT
                     RAQAHYEAAAPGITLLSPASQACMRTAYALYGGILDEVAAQGYDVFARRALVPQRRRLA
                     VAARALLTPTGSPVAVPGPSLVRR"
     misc_feature    10965..10983
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            10984..12138
                     /locus_tag="GA0074696_RS01635"
                     /old_locus_tag="GA0074696_0331"
     CDS             10984..12138
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="GA0074696_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0331"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_088964297.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.8e-47, bitscore:
                     158.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAGNALRVAPAQPGATDDPVRRVLAAFTKELVKGVDDTLA
                     AFLATEVDSLTEIDAAMGGFAATARDSVLAGGKRVRPTFAYWGWRGVVGGAEPLPTVLP
                     AFAALELLHTFALVHDDVMDASDTRRGRPTAHRAATARHVAAGYAGDPARFGEAVAVLV
                     GDLCLVWADRLLSHATVAPAQLFEVRRCYDQMRIETVAGQYLDVLGENDPANWSVDRAL
                     RVARYKTASYTVQRPLLFGACLAGVAADTPLIAAYTRYGLAVGEAFQLCDDLLGVYGDP
                     ATTGKPAGDDLRTGKPTALLMLARQLATPGQRRALERAGPVTGARDVARLAELVADTGA
                     VSRVERMISDRVSEALTALDTASIDETARTALTGLATAATMRRA"
     gene            12167..13648
                     /gene="crtI"
                     /locus_tag="GA0074696_RS01640"
                     /old_locus_tag="GA0074696_0332"
     CDS             12167..13648
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454362.1"
                     /locus_tag="GA0074696_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0332"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_088959449.1"
                     /sec_met_domain="DAO (E-value: 2.4e-17, bitscore: 62.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVNGRTDRVVVVGAGLGGLACALHLAGSGRQVTVVEREPVPGG
                     RAGRLAVDGYEFDTGPTVLTMPDLIAEALGAVGEELDDWLDLTPVDPAYRAYYPDGSTL
                     DVITDTTRMAAEIARVCGPREADGYLRFVDYARNLWHWERTDFIDRNLDAPTDLLTANL
                     VKLLANGAFRRLQTKINQFFRDPRTQRIFSFQAMYAGLAPHDALAIYSVIAYLDSVAGV
                     YFPRGGIHAVSRGMAGAAEKHGVQFRYGTTVTRVETANGRAIGVLTADGELIPADVVVL
                     NPDLPVAYRDLLPPARRRKLTYSPSCVVLHVGSTQGYEKIAHHNIHFGRKWKGTFDEVI
                     RRGELMTDPSLLVTNPSRTDPAVAPAGRHTYYVLAPVPNLERGPFDWRGDLSRRYADQL
                     VATLEERGYVGFGAGIEVLRTITPAEWEEQGMAAGTPFAAAHSLFQTGPFRPSNLHRQL
                     PNVVFTGSGTQPGVGVPMVLISGKLAANRITGAGR"
     gene            13725..14330
                     /gene="idi"
                     /locus_tag="GA0074696_RS01645"
                     /old_locus_tag="GA0074696_0333"
     CDS             13725..14330
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019870057.1"
                     /locus_tag="GA0074696_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0333"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_088964298.1"
                     /transl_table=11
                     /translation="MTSREGHLVELVDDRGNVLGEATVAAAHQAPGRLHRAFSVLLVDP
                     AGRVLLQRRAPVKTRFPQRWANSCCGHPRPAESLVEAANRRLAEELGAAPVTLTEVGVY
                     LYYAEDPATGRVEFEYDHVLRADVPADVTVLPDPDEVSELRWVDPVRLMAEIDADPCAY
                     APWLGGVVSRLLRAGGPAGTTIPSGVPADDASERSGGR"
     gene            14320..15261
                     /locus_tag="GA0074696_RS01650"
                     /old_locus_tag="GA0074696_0334"
     CDS             14320..15261
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730890.1"
                     /locus_tag="GA0074696_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0334"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_088959450.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSQHIPGHHRRYT
                     PADLARLEIMRRLTAEGITPAEAARWAKQSPGVGPAAGVRLRAGAGRDGGGQAIPVGRA
                     GPVARGLARAAMRLDSAAISETIANAVARDGVVATWDGLLRPVLAGIGERHAATAGLIE
                     VEHLMSRCVSEAFATVARPGPAAGPARILLACADEEQHTLPLEALAASLAEANVAYRML
                     GARVPLAALIEAVNRTGPAAVVLWSHTRATADPGQLSALLGMVRRPLLVLAAGPGWQAD
                     TLPAGVVRPVDLTEAVSLALAVRDSLDQSGGA"
     gene            15336..16136
                     /locus_tag="GA0074696_RS01655"
                     /old_locus_tag="GA0074696_0335"
     CDS             15336..16136
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473455.1"
                     /locus_tag="GA0074696_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0335"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_088964299.1"
                     /transl_table=11
                     /translation="MRARPVLAAALGLVLLLAVGCGEPQRDPQQAAAPAPTAAASPSPV
                     TTPSPRATPRPATKPKPKLRPKPTTLPAGLRRATGVRAVALTFDDGPDPAWTPKVLDQL
                     RAARVKATFCLVGTQIRKHPELVARMVREGHQLCNHSWRHDLDLGRRPVAEIRADLVRT
                     NGAIQAAAPGAKVPFYRQPGGRWTPEVVAVARQLGMRSLHWSVDPQDWAKPTVATLAER
                     VHGAARPGAIVLMHDGGGDRSHTLAACPHLIIDLKRRFGVAPPR"
     tRNA            16292..16364
                     /anticodon=(pos:367491..367493,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0074696_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0074696_0336"
                     /product="tRNA-Glu"
     gene            16292..16364
                     /locus_tag="GA0074696_RS01660"
                     /old_locus_tag="GA0074696_0336"
     tRNA            16398..16474
                     /anticodon=(pos:367597..367599,aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0074696_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0074696_0337"
                     /product="tRNA-Asp"
     gene            16398..16474
                     /locus_tag="GA0074696_RS01665"
                     /old_locus_tag="GA0074696_0337"
     tRNA            16577..16650
                     /anticodon=(pos:367776..367778,aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0074696_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0074696_0338"
                     /product="tRNA-Phe"
     gene            16577..16650
                     /locus_tag="GA0074696_RS01670"
                     /old_locus_tag="GA0074696_0338"
     gene            complement(17118..18011)
                     /locus_tag="GA0074696_RS01675"
                     /old_locus_tag="GA0074696_0339"
     CDS             complement(17118..18011)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015338.5"
                     /locus_tag="GA0074696_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0339"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_088959451.1"
                     /transl_table=11
                     /translation="MSEESASLRVLTLNALAPFFADWPRRRAVLVDGLRELRPDVVALQ
                     EVAGGGDLDEAGGLLGPDYHLVPHPGRSADGVGAVLGSRWPVRTVGVVDLHVAPRTAAL
                     PWSAAVVVEVAVPPPLGPVLVVHHKPAWQYDAEYERELQAVRTARYIEELVAERRSEPL
                     EPDGPDTEPHVVLLGDFDAAPDAASVRFWTGRQSLAGISVCYEDCWTAVRREEPGHTFS
                     PGNPLIRAGLMPLDRGRRIDYILIRCGPHGPTLDVVDCRRVFAEPVAGVWASDHFGVLA
                     DLCLPPHPPGTWMGIR"
     gene            18756..19070
                     /locus_tag="GA0074696_RS01680"
                     /old_locus_tag="GA0074696_0340"
     CDS             18756..19070
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012798.5"
                     /locus_tag="GA0074696_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0340"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_088959452.1"
                     /transl_table=11
                     /translation="MAGRPGRCRPEVASRPGPGRRGPLAGRLDDLTFHDLRHTGQTLAA
                     QTGATLADLMKRLGHSSMAAARRYLHAVDGRDREIAKALSELAAHGDVARLPRHITMRS
                     "
     gene            complement(19857..20414)
                     /locus_tag="GA0074696_RS01685"
                     /old_locus_tag="GA0074696_0341"
     CDS             complement(19857..20414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007464308.1"
                     /locus_tag="GA0074696_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0341"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_231925225.1"
                     /transl_table=11
                     /translation="MADLIASCPWLLNVLTTVREAGLPDAWVGAGVLRDLVWSQRYGGG
                     FNPQDVRDVDVAFFDANDLTPGNDVAATELLRRHQPAVPWEATNQAAVHIWYERVFGTG
                     PVDALRSIADAVATWPETATCVAVRLDSAETLHVCAPLGLDDLLSGTWRRNLHRVTLEL
                     SRSRLARHEPSRRWPKVKVIPP"
     misc_feature    20399..20413
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(20447..20466)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.78"
                     /tool="antismash"
     gene            complement(21025..21351)
                     /locus_tag="GA0074696_RS01700"
                     /old_locus_tag="GA0074696_0343"
     CDS             complement(21025..21351)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0074696_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0074696_0343"
                     /product="hypothetical protein"
                     /protein_id="WP_088959453.1"
                     /transl_table=11
                     /translation="MSPSDTDPLLLAGRLVIVVVSLFVLVLGVRVAVSRRFPVAWVRVA
                     RLPASQRSQPVRIGGSQALLGASLLIQQAPFLIPMPYLVGRALFAVALLLLVVAVGWFV
                     LRRD"
     gene            21465..21824
                     /locus_tag="GA0074696_RS01705"
                     /old_locus_tag="GA0074696_0344"
     CDS             21465..21824
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012181861.1"
                     /locus_tag="GA0074696_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0074696_0344"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_088959454.1"
                     /transl_table=11
                     /translation="MAIDCAPGLAPAVALFRSLGDPTRLAILRRIATGEARVVDLTGEL
                     GLAQSTVSKHLACLRDCGLIDYRAEGRQSFYALTRPELLDLLRSAEQLLAATGEAVALC
                     PTYGTPAGSPAEVSA"
     misc_feature    complement(21952..21966)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
ORIGIN
        1 caccgaccac ccaggagagc acgtgacggc gtcatccacc atcgccccac ccccggtcgg
       61 ggcactgcgg gacctgctgc accagcacca ccacgacctg cccgacaccg acccggagcg
      121 gatcctcgcc ctggtctcct cggggcgcac cgccggcgcg gacaccgacg agctgacccg
      181 gctggccatc gcggcggcgg ccgggctcac cgccgaggag cccgggtacg cccggctggc
      241 cgcccgcctg ctcgccgggc ggatcgccga cgagaccacc ggccagggca tcgacagctt
      301 cagcgacagc gtcgccgccg cgtacgccga gggtctgctg gacccgggct tcgccggctt
      361 cgtcgcgacg cacgccgccg ccctcgacgc cctggtcgac cacgccggcg acgacgcctt
      421 cgagtacttc ggactgcgca ccctgcacga ccgctacctg ctgcgccacc cgcgcagccg
      481 ggcggtgctg gaacggccgc agcacttctg gctgcgggtg gccaccggcc tgtccgacac
      541 cgtggagcag gccggcgagc tgtaccggct gatgtcccgg ctggcctacc tgcccagctc
      601 cccgacgctg ttcaacgccg gcgcccggca ccagcagctc tcctcctgct tcctggtcga
      661 ctcgccccgc gacgagctgg actcgatcta cgagcgctac acgcaggtgg cgaagctgtc
      721 caagttcgcc ggtgggatcg gcatctcgtg gtcccgggtg cgctcgcggg gtcgctgatc
      781 cggggcacca acggccgctc caacggcatc gtgccctggc tgcgcaccct cgacgccagc
      841 gtcgcggcgg tcaaccaggg cggccggcgc aagggcgcgg cctgcgtcta cctggacacc
      901 tggcacgccg acatcgagga gttcctggag ctgaaggaca acaccggcga cgaggcccgg
      961 cgtacgcaca acctgaacct ggccaactgg gtgccggacg agttcatgcg ccgggtcgag
     1021 gcggaggccg actggtcgct gttcgacccg aaggaggtgc cggagctggt cgacctgtgg
     1081 ggcgcggagt tcgacgccgc gtaccgggcg gcggaggccg ccggcagggc ggcgcggacg
     1141 ctgccggccc gcaccctgta cggccggatg atgcgcaccc tggcgcagac cggcaacggc
     1201 tggatgacgt tcaaggacgc ggcgaaccgc acctgcaacc aggtctgcgc gggcggcggc
     1261 gtggtgcacc actccaacct gtgcaccgag atcctggagg tgaccagcga cgacgagacg
     1321 gccgtctgca cgctcggctc ggtcaacctg gccgcccatc tggtcgacgg tggcgtggac
     1381 ttcgccacgc tcgccgcgac ggtgcggctg gcggtcgggg cgctggaccg ggcgatcgac
     1441 cggaactggt tccccaccga gcaggcggcc accgcgcacc ggcggtggcg gccgctgggg
     1501 ctgggtgtga tggggctggc cgacgtcttc gccgcgctgc ggctgccgtt cgactcgccg
     1561 gcggcgctgg ccctgtccac ccggatcgcc gaggaggtcg ccctggccgc gtacgacgcc
     1621 tccgccgacc tggcggcgga gcgcggcgcg cacccggcgt acccgctgac ccgggcggcc
     1681 ggcggggtgc tgcacccgga ccactggccg gacgcccggc cgacccggcc ggaggcgtgg
     1741 gcggcactgc gggagaaggt ggcccggcac gggctgcgca actcgctgct ggtggcgatc
     1801 gcgccgacgg ccaccatcgc ctcgatcgcc ggctgcgccg agtgcgtcga gccgctggtc
     1861 tcgaacgtct tcaagcggga gaccctctcc ggggagttcc tccaggtcaa ccggcatctg
     1921 gtcgccgacc tgaagcggct gggccggtgg accccgcaga cccgggaagc gatcaagcgg
     1981 gcggacggct cggtccagga gctggacctg ccggcggagc tgaaggcgtt gcaccgcact
     2041 gcctgggagc tgccgcagaa ggcgctgatc gacctggccg ccgcccgcgc cccgtacgtg
     2101 gaccagtcgc agtcgctgaa cctgttccag gccagcccga ccatcggccg gctctcctcc
     2161 atgtacgcct acgcctggcg ggccggcctg aagaccacct actacctgcg ttcccgcccg
     2221 gcgacccgga tcgcgcagac cacggtcgcc gccgcgccgg ccgccgcacc cgtgccctcg
     2281 ccgcgaacgg cggcacccgc cctgctcacc ctgtccgtcg gcgagagcga cgcggtcgcc
     2341 tgctcgctgg agaaccccga gatctgcgag gcctgccagt gacgatgctg ctcgaccccg
     2401 gcatggacct gaccctgcga ccgatgcgct acccggactt ctacgagcgg ttccgggccg
     2461 ccatccgcaa cacctggacg gtggaggagg tggacctggc ctccgacgta cccgatctgg
     2521 ccacgctctc cgtcggcgag cggcacctgg tccaccgcct ggtggcgttc ttcgccaccg
     2581 gcgactcgat cgtggcgaac aacctggtgc tcaacctcta ccagcacgtc aacgcgcccg
     2641 aggcccgcct ctacctctcc cgccagctct acgaggaggc ggtgcacgtc cagttctacc
     2701 tgaccctgct cgacacctac ctgcccgacc acgaggagcg ggcgaaggcg ttcgcggcgg
     2761 tcgagcacat cccgtcgatc cgcgacaagg cggagttctg cttccgctgg atcgactcga
     2821 tcggcggcct ccaccggctg gagacccggg cggagcggcg ggcgttcctg ctcaacctga
     2881 tctgcttcgc ggcgggctgt tcttctacgg cgccttcgcc tacgtctact ggctgcgctc
     2941 gcgcgggctg ctttccgggc tggccaccgg caccaactgg gtgttccgcg acgagtcgat
     3001 gcacatggag ttcgccttct cggtggtcga caccgtccgc gccgaggagc cgtcgctgtt
     3061 cgacgaggcg atggcggatg aggtgcggac catgctggac gaggcggtga cggccgagct
     3121 ggccttcgcc cgggacctct gcggggacgg cctgccgggc atgaacaccg ccgacatgcg
     3181 ccgctacctg gagtacgtcg cggacgcgcg gctcgcccgg ctcggcctgc cgcccgcgta
     3241 cgggtcgacg aacccgttcc cgttcatgga gttgcaggac gtgcaggagc tgaccaactt
     3301 cttcgagcgg cgggtgtccg cgtaccaggt ggccgtcggc ggtgaggtca gcctggacga
     3361 cgacttctga gggcgcatag cctcggccca tgcctgtcca ccggctcgat cgggtcgacg
     3421 cccggcggat cgcggtgcgc gcccaactgc tggacgcgca ccgcccgccg gacctgctga
     3481 ccgtggtcaa caggttgacg ttcctgcaac tggatccgac ggccgccgtg gcgcccagcg
     3541 ccgacctcgt cgcctggacg cggctgggcg ccgggtaccg gccggaccac ctgcggcagg
     3601 cggtggagca ggaccgcagc atgttcgagc accaggccat ggtgtggccg acggcggacc
     3661 tggggctgca cctcgccgag atggcggcgt ggccgccgga gggctcgcgc aagcacgcct
     3721 ggctggcggc gaacgccacg ttccaccggt tcgtgctcga cctgctgcgc gactccggcc
     3781 cgctgctgtc ccgcgacgtg ccggaccgca gcgtggtgcc gtggccgtcg accggctgga
     3841 cgaacaaccg caacgtcacc caactgctgg agatcctcgc cgcccgcggc gagatcgcca
     3901 tcgccgaccg ggtcgggcgg cagcgccggt gggatctggc cgagcgggtc tatccggccg
     3961 gcacgacggc cgtcccggcg gacgaggccc ggcggatgcg tgacgagcgg cggttgcgtt
     4021 cgttgggcat cgcccgggcg tcggtcgtcg gggaggcggg tgaaccggcg caggtcgagg
     4081 gcaccgccgg cacgtggcgg gtggacccgg cggccctcgg ccagccgttc gccggccgta
     4141 ccgcgctgct gtcgccgttc gaccggctgg tccacgaccg gaagcgggcc cgggagctct
     4201 tcgacttcga gtacgtgctg gagatgtacc tgccgaaggc gaagcgccgc tggggctact
     4261 tcgcgctgcc cgtgctgcac cacgaccgac tcgtcggcaa ggtggacgcc acggccgacc
     4321 accgggccgg cgtcctgcgg gtgcacgcga tccaccagga cgcccccttc acccgcgccg
     4381 tcaccgcggc ggtcggcgcc gagctggacg cgttggcgtc gtggctcggc ctgaccgagg
     4441 tcacccgcat ctcgtaggcg acgtcgggtg acggtcgtcc cgggccggcg gccggtgcca
     4501 tcaggagcgc cggagctgcg cccccaggcc gtgccggtcg atctggatcc agtactcgac
     4561 gattcgcccg tcccgcaccc ggtagaccgc gctggtcacc tgcgtcacgg gcaggccggt
     4621 gggtgggaac ccgtccacct cccccaggtg ccgcccgtgt tgggtccacc gcgcgtagac
     4681 ccggtcaccg gccccgaaca gctcgtccac ccgcaggctg aagtccccgt acgcggcgag
     4741 catgtcgcgg acgtgcgccg cgtactgcgc cggggtgcgc tccacggtca gctcgtcctc
     4801 ggcctgcacc tggtgagcga gcacccggtc ggccatgagc cggtgagcgg cgtccgggtc
     4861 gacacccgag cggacccgtg tcatgaactc ccgcacgacc cgcgtctccg tcgtctccat
     4921 gtcgtcgagc ctcccgcacc ggccgcccac cgctgaagat ccaatcctgg acgcccggct
     4981 accgggcgcg gtgcccaggt gaggaaccgc tcggtcacgg cggccgcgtc ccacttccgg
     5041 gcgcggccgc cgcccacgct gcgaggtgcc cccccccccc gagtcgttca cgtcatcagg
     5101 tctgtagcgc acggcacccc gggggtctcc gggcgcggcg cagcccgcgg tggccaaggt
     5161 cagcgaccac ccgcccaccg gtcggtgtgc agcgcgtcgg ccagcgggcg cttctgccgc
     5221 caaccgtgcc gggccaggtc gggcacctcc tccaggtgcg tcaccggccc gacgcagagc
     5281 caggccaccg gccggatgcc ggtgggaatg cccagcaggt cggccaggaa cggctcccgg
     5341 tagaaggaga cccagccgac gccgaggccc tcggcggtgg cggccagcca gaggttctgg
     5401 atggccaggc agaccgagta gaggccggcg tcggcgatgg cgtgccggcc cagcacggcc
     5461 gggccgcccc gcgacgggtc gtaggtcacc acgaccgaca gggtcgactc cagcacaccg
     5521 tcgatcttga tgcgggcgaa ccgtgccgcc gcctcaccgg acagggtggc cgcgaaggtg
     5581 tcccgttccg tccgcacgtg ctcgtggaag cggcggcgca gcccggcgtc ccggaccagg
     5641 acgaagtccc acggctgcga gtagccgacg ctgggcgcgg cgtgcgcggc gtcgaggacg
     5701 cggtgcaggg tgtcgtccgg caccggcgcc ccggtgaact cggcccggac gtcccggcga
     5761 cggtggatgg cggtgtagag gtccacggca ggctcccgct gcgcaaggcc cacccgggac
     5821 gggtgggcgg tcgacgcgag gccggtcttc ggactcccgg atcgacgcct ggccgcccgc
     5881 cttcccagcc gtatggccag tggctgcgct ctcgcgcgtg gacggtggct ccccggtcac
     5941 cgcggcgggc ccgtgccgga tttgcaccgg cttcccgatt ctccccgcgc acgcggggca
     6001 cctcgcatga tcgttgccgt cggcgatggt agcggcccgg ccgggcggaa cgggcatgcg
     6061 caccggggtt gccgcgccct ggagtgacgg actcccgggc cgatccgccc gaccgcccct
     6121 ggcgtgccgg cgccgccggg cggcatgctg tgccgatggc cgtacacgtc acgcacgacg
     6181 gaccggtgac cacggtgatc ctcgaccggg cggcgtcgcg caacgccgtc gacggcccca
     6241 ccgcgcgggc gctcgccgac gcgttccgcg ccttcgaggc cgacccggag gcccgggtcg
     6301 cggtgctctg gggcgccggc ggcacgttct gctccggcgc cgacctcaag gcgatcggta
     6361 cgcctagcgg caaccgggtc gagccggacg gcgacggccc gatgggtccg acccggattt
     6421 cgctgtccaa gccggtcgtc gccgcgatct ccgggtacgc cgtggccggc ggcctggagc
     6481 tggcgctctg gtgcgacctg cgggtcgccg agtccgacgc cgtgttcggg gtgttctgcc
     6541 ggcgctgggg cgtaccgctg atcgacggtg ggacggtccg gctgccgagg ttgatcgggg
     6601 agagccgggc gatggacctg gtcctcaccg gccgcccggt gcccgccgag gaggcgtacg
     6661 cgatggggct ggtcaaccgg ttggtcccgc cgggtgaggc gcgggcggag gccgaacggt
     6721 tggccgccga gatcgcccgc cacccgcaga cctgcctgcg caacgaccgc gcgtcggtgc
     6781 tcgccaccgc cggcctgacc gagccggagg cgctcgccac cgagctggcg tacggcatgc
     6841 ggtcgctgaa cacggacgcg gcggccggcg cggcccggtt cgccgccggg gccggccgcc
     6901 acggcaccgt cagctgaggt cgcgcagggc gtcctcgatc gcccggtgga acgtcgggta
     6961 cgcgtagatc atgtgccgga ggtggctcag cggcaccgcc gcgtgcaccg ccaccaccag
     7021 cgccgacagc acctcgccgc cggccgggcc gacggaggtc gcgccgacca gcacgccctg
     7081 gtcggcgtcc gcgacgagct tgatgaagcc gtcgttgccg gccttgtgga tccaaccccg
     7141 ggcggacgac gacagctggg cgaagccgac ctgcacgttg atgccgcgct ggcgggcctg
     7201 gtgctcggtg agcccgaccg caccgacctc cggatcggtg aaggtgaccc ggggcagcgc
     7261 ccggtagtcg gcgcggggca gggtaccggc ggcgccgctc gggccggtcg cggtcatcgc
     7321 gccgccgacc gcgctcgccg cgcccatcgc accgcccacc acgctggccg tcccgctcgg
     7381 gtcggggcca ctgtcggcgt gccgggtgcg gtcgagcacg ccggcgatga cgatcgccgc
     7441 ctggtacatc gcgatgtggg taaaggcccc ctcaccggtg acgtcgccga cggcccagac
     7501 accgtcggtc acccgcatct gcccgtcgac cggcaggtag cgctgcccgg ggtcgacgcc
     7561 gatcgagtcc aggcccagct cctccaggtg cgcccggcgc ccggtgacca ccagcagccg
     7621 ctccgcgtgg aacgcgtcgt cgccggcgtg cacggtgaag gtggcaccgt cgtggctgac
     7681 ccgttccgcc ttgacgccgg tgcggatctc caccccgtcg gcccgcagcg ccttctcggc
     7741 cacctcggag gactcgggct cctcgaccgc gaggacccgg tccgccgcct cgaccacggt
     7801 cacccgtacg ccgaaccggg cgaacacctg cgccagctcc agcccgatcg cgccgccgcc
     7861 gagcaccagc agcgattcgg gcagctcctc gacctcgatc gcctggtggt tcgtccagta
     7921 cggcgtgtcg gccaggccgt cgatcggcgg cacggagggc cgggtgccgg tgccgaacac
     7981 gatcccgtgc cgggcctgga tgacctggtc gccgacgcgt acccggccgg ggccgtcgag
     8041 ccgggcgctg ccgcgcagga accgcccacc ccggccggtg aaccggtcga ccgccaccgt
     8101 gtcgtcccag gtgtcggtgg cctcctcgcg gatccgcttg gccaccggcg cccagtccgg
     8161 ctggacctgg gccgaaccgg ccagctcgtt gacccgccgc gcctcggcga gcgcgttcgc
     8221 cgccctgatc atcatcttgc tggggatgca cccccagtac gggcactccc cgccgaccag
     8281 gtcacgttcg atgccgacga cgctcagacc ggcctcggcg agccgcccgg ccacctcctc
     8341 gccgccgacg cccaacccga ccacgaccac gtccaccact tccggctccg ccatgccgtc
     8401 agcattcccc agccaccgga cgccggccag cggaccgcac cggaattccc gcgcccgtaa
     8461 tcattgctac cgcctacggt ggccgcatgc ccgatcgctt cgcccccgtc cgcgactgct
     8521 tccaggatct gctggccacc ggccgggaga ccggcgccgg cctgaccatc tggtacgacg
     8581 gccacccggt ggtcgacctg ggtgccgaca gccgcggggc gtggcggccg gacacgctgg
     8641 tgaacgtcta ctcggtcggc aagccggtcg cggcgctctg cctgctgctg ctcgtcgacc
     8701 ggggtcggct cgacctggac gatccagtgg cgacccactg gcccgggttc cgcacccccg
     8761 ccacggtccg ccaggtgctg agccacaccg ccggcctgcc gaccttcccg gtggcccggc
     8821 ccgccgaggc ggtcgccgac tgggagctgc tctgcgccga cctggccgcc gccgacccgg
     8881 agtgggagcc gggcagcgtc gcgggcgagc acgcctggac gtacgggcac ctggtgggcg
     8941 agctggtccg ccgggtcgac gggcggtcgg tggggcggtt cctggccgag gagatcgccg
     9001 acccgtggcg cctcgacctg ggcttcggcc tcggggcagc ggaccagcgg cggtgcgcgg
     9061 acctgtcgta cggcgatccg gcctggccgg tgcggatgct gggtgagccg ggatcgctgc
     9121 gggcccgggc actgagcaac ccacccggcg gcctcgacct ggcggtggtc aacagcccgc
     9181 tctggcgggg cgcgcaggtc ccggcggtca acctgcacgc cacggcgtcc gcgctggccc
     9241 ggctctacgc gggcctggcc gccggcggca ccctcgacgg ggtacgcctg ttcagccccg
     9301 agctggtcgc cgaggccacc cgggtccagt acgacggccc ggacctggtg ctcgatcgcc
     9361 gggcctgctg gacgctgggg atgcagcgcg agccggacgg gagctggggc atgggcggga
     9421 tcggtggcag cagcgcctgg gccgacccgg agcggggcta cgtcttcggc tacgccacgg
     9481 cccacctggc cgaccacgat cgggtggacg agctggtcga ggtgctgcac tcctgcctct
     9541 gacgtcggcg gcagggtcac cccgcgtcac gagcccccag catcacgcac ggtgacggcc
     9601 gaggactccc ccgcattgcc actcggacgc tttgctctgc tgccgccacg gcaacacgag
     9661 aactgagcag cgcatccact caaggccatc ctgacggcgc gggcgtcggt cgttaccgag
     9721 ggttgctgtt gccggggagg cagcagagca aagcgtctga gcagatgctc ggcgggaagc
     9781 agcgccctca cgctcagtgc acgctcccgg cgggcctcgc aggtccggca acgagcggac
     9841 gggtcagcgc atccagaccg ggtcgacgcc gggcgcctcc agcggcggcg gatagcccag
     9901 cttccggcgt acctcgccgg ggagccgcca cggttggtgc accgccttcc ccgccaccga
     9961 cgtcagttcg ggaacccagc acccaccgcg gtacgcgcac tcaccgtcga accaggctcg
    10021 gcccgggtac ggcgaccggg ctgccggtcg gggtgagcag ggcccgggcg gccaccgcca
    10081 gccggcgacg ctgcggcacc agcgcccggc gggcgaacac gtcgtagccc tgcgcggcga
    10141 cctcgtcgag gatcccgccg tagagcgcgt acgcggtccg catgcacgcc tgcgaggcgg
    10201 ggctgagcag ggtgatgccc ggtgcggcag cctcgtagtg cgcctgggcg cgggtcacct
    10261 cgtacccgat caggtctcgg atcctcggcg tggtgcgggc ctgatccttc gcggcgagca
    10321 ggtcgtcgcg ggtgacgccg aacttggcca ggtcctcgtc gggcaggtag gtgcggcccc
    10381 ggtcgaggtc ctcggcgacg tcccggatga agttggtgag ctggaaggcg aagccgagct
    10441 ggcgggccgg ctcgcgggcc gccgccgggt cggagctgcc gaggatcggc agcatcatgg
    10501 tgccgatgac cgccgccgag ccttccatgt agtcgagcag gtcgtcgtag gtcgggtacg
    10561 acagcacggt caggtccatc gccatgctgc gcaggaacga cgcgaagtcg gcgcggtcga
    10621 gatcgaatac ggcgatggtg tgcagcacgg ccgggagcag cgggtcgtcg accggttcac
    10681 cgtgcaggcc ggcgacgaac tccgccgacc actggtccag ccgggcggcg cgctcggcgg
    10741 gcggcagctc ctcggtgcgg tcgacgatct cgtcggcgta gcgcgtgaat ccatacaggg
    10801 cgtgcacatg acgtcgtttc cacgcgggga gcagccgggt ggcgagatag taggtgcgac
    10861 cgtgccgtcg gtgcagctcc tggcagcggg cataggcagc ggtgagatcg gtgtccaccg
    10921 gccctcctcg aaattcgacg cagcaatcga cgcaactcgt aaccctaggg tatgctcgcc
    10981 gacatggcca acgacgcagt cgcaggtaat gcgctccgcg tcgcgccggc acagccggga
    11041 gcgacggacg atccggtccg ccgcgtactg gccgcgttca cgaaagagct ggtcaagggg
    11101 gtggacgaca ccctggcggc cttcctggcc accgaggtcg actcgctcac cgagatcgac
    11161 gcagcgatgg gtggtttcgc ggccaccgcc cgcgacagcg tgctggccgg cggcaagcgg
    11221 gtccggccga ccttcgcgta ctggggctgg cgcggggtgg tcggcggcgc ggagccactg
    11281 ccgacggtgc tgccggcgtt cgccgccctg gaactgctgc acaccttcgc actggtgcac
    11341 gacgacgtga tggacgcctc cgacacccgc cgcggccggc ccaccgcgca ccgcgccgcc
    11401 accgcccggc acgtcgccgc cgggtacgcc ggcgacccgg cccggttcgg cgaggcggtg
    11461 gccgtgctcg tcggcgacct ctgcctggtc tgggccgacc ggctgctcag ccacgccacc
    11521 gtggcaccgg cccagctgtt cgaggtgcgg cgctgctacg accagatgcg gatcgagacg
    11581 gtcgccgggc agtacctcga cgtgctgggc gagaacgatc cggcgaactg gtcggtggac
    11641 cgggcgctgc gggtggcccg ctacaagacc gccagctaca ccgtccagcg cccgctgctc
    11701 ttcggcgcct gcctggccgg cgtcgccgcc gacacgccac tgatcgccgc gtacacccgc
    11761 tacggcctgg ccgtcggcga ggcgttccaa ctctgcgacg acctgctcgg cgtctacggc
    11821 gacccggcga ccaccggcaa gccggccggc gacgacctgc gtaccggcaa gccgaccgcg
    11881 ctgctgatgc tggcccgcca actcgccacc cccggccagc ggcgggcgct ggagcgggcc
    11941 ggcccggtca ccggcgcccg ggacgtggcc cggctggccg aactggtcgc cgacaccggg
    12001 gcggtgtccc gggtcgagcg gatgatctcc gaccgggtgt ccgaggcgct gaccgcgctg
    12061 gacaccgcgt cgatcgacga gaccgcgcgc accgcgctga ccggcctcgc caccgccgca
    12121 accatgcggc gggcatgatg agcgaccttg cgaaggaggt ggtcacgtgc ggaccgtgaa
    12181 cggacgtacg gaccgggtgg tggtcgtcgg cgcgggcctg ggcgggctgg cgtgcgcgct
    12241 gcacctggcc ggcagcggcc ggcaggtgac cgtggtggaa cgcgagccgg tgccgggcgg
    12301 ccgggccggc cggctggccg tcgacgggta cgagttcgac accggcccca ccgtgctcac
    12361 catgccggac ctgatcgccg aggcactggg cgcggtcggc gaggaactcg acgactggct
    12421 ggacctcacc ccggtcgacc ccgcctaccg ggcctactac cccgacggct cgacgctcga
    12481 cgtcatcacc gacaccaccc ggatggccgc cgagatcgcc cgggtctgcg gcccccgcga
    12541 ggccgacggc tacctgcgct tcgtggacta cgcgcgcaac ctgtggcact gggagcggac
    12601 ggacttcatc gaccgcaacc tggacgcccc gaccgacctg ctcactgcca atctggtgaa
    12661 actgctggcc aacggcgcgt tccggcggct tcagacgaag atcaaccagt tcttccggga
    12721 cccacgtacc cagcgcatct tctccttcca ggcgatgtac gccggcctcg cgccgcacga
    12781 cgcgctggcc atctacagcg tcatcgcgta cctcgactcg gtggccgggg tctacttccc
    12841 gcgcggcggc atccacgcgg tctcccgggg catggccggc gccgccgaga agcacggcgt
    12901 gcagttccgg tacggcacca cggtgacccg ggtggagacc gccaacggcc gggccatcgg
    12961 cgtgctgacc gccgacggcg agctgatccc ggccgacgtg gtggtgctca acccggacct
    13021 gccggtcgcc taccgtgacc tgctgccccc ggcccgccgg cgaaagctga cctactcgcc
    13081 ctcgtgcgtc gtgctgcacg tcggctcgac ccaggggtat gaaaagatcg cccaccacaa
    13141 catccacttc ggacggaagt ggaagggcac cttcgacgag gtcatccggc gcggcgagct
    13201 gatgaccgac ccgtcgctgc tggtcaccaa ccccagccgg accgatccgg cggtggcccc
    13261 ggccgggcgg cacacctact acgtgctggc gccggtgccc aacctggaac ggggcccgtt
    13321 cgactggcgc ggcgacctga gccggcgcta cgccgaccag ctcgtggcga cgctggagga
    13381 gcgcgggtac gtgggcttcg gcgcgggcat cgaggtgctg cgtacgatca cccccgccga
    13441 gtgggaggag cagggcatgg ccgccggtac gccgttcgcc gccgcgcaca gcctcttcca
    13501 gaccggtccc ttccgcccgt cgaacctgca ccggcaactg cccaacgtcg tgttcaccgg
    13561 ctccggcacc cagccgggcg tgggcgtacc gatggtgctg atctccggga agctggcggc
    13621 caaccggatc accggtgccg ggcggtgagc gcgcggagcg cggcccggcc gcacggcaca
    13681 cgcaggacgg gcgcgatgca cacgcggaac ggggggcggg tccggtgacg tcccgggaag
    13741 ggcacctggt cgagctggtc gacgaccgcg gcaacgtgct cggcgaggcc accgtggccg
    13801 cggcccacca ggcgccgggg cggctgcacc gggccttctc ggtgctgctg gtcgacccgg
    13861 ccggccgggt gctgctgcaa cggcgggccc cggtgaagac ccggttcccg cagcgctggg
    13921 ccaactcctg ctgcggccac ccccgaccgg ccgagtcgct ggtggaggct gccaaccgcc
    13981 ggctggccga ggagttgggc gcggccccgg tcacgctgac cgaggtcggc gtctacctct
    14041 actacgccga ggatccggcc accggccggg tcgagttcga gtacgaccac gtgctgcggg
    14101 ccgacgtgcc ggccgacgtc accgtgctgc cggaccccga cgaggtgtcc gagctgcgtt
    14161 gggtcgaccc ggtacggctg atggccgaga tcgacgccga cccctgcgcg tacgcaccct
    14221 ggctgggcgg ggtggtgagc cggctgctgc gcgccggcgg ccccgccggc accaccatcc
    14281 cgtccggcgt tccggcggac gacgcgtcgg agcggtcggg tggccgatga ggcgctgagc
    14341 gcgggggccg tcgcacgccg actgggcgtg gcggtcacca cgctgcgtac ctggcaccag
    14401 cgctacggcc tcggtcccag ccagcacata ccgggtcacc accggcgcta cacgccggcc
    14461 gacctcgcgc gcctggagat catgcgtcgg ctcaccgcgg aggggatcac cccggccgag
    14521 gcggcccgtt gggcgaagca gagccccggg gtcggtcccg ccgccggggt gcggctgcgc
    14581 gccggagccg gtcgggacgg cggcgggcag gcgatcccgg tcggccgggc cggcccggtc
    14641 gcccgtggtc tggcccgggc cgccatgcga ctggactccg cggcgatcag cgagaccatc
    14701 gccaacgccg tcgcccggga cggcgttgtc gccacctggg acggcctgct gcgtccggtg
    14761 ctggccggca tcggggagcg gcacgccgcg accgccggtc tgatcgaggt cgaacacctg
    14821 atgtcccggt gcgtctccga ggcgttcgcc acggtggccc ggcccggccc ggccgccggc
    14881 ccggcccgga tcctgctcgc ctgcgccgac gaggaacaac acaccctgcc gttggaagcg
    14941 ttggccgcct ccctcgccga agcgaatgtg gcgtatcgca tgctgggtgc ccgggtgccg
    15001 ctcgcggcgc tgatcgaggc ggtgaaccgg accggaccgg ccgcggtggt gctctggtcg
    15061 cacacccgcg ccaccgccga cccggggcag ctgtccgccc tgctcgggat ggttcgacgc
    15121 cccctgctgg tgctggccgc cggccccggc tggcaggccg acacgctgcc cgccggagtg
    15181 gtccggccgg tcgacctgac cgaggcggtg tcgctggcgt tggccgtccg ggactcactg
    15241 gatcagtcgg gcggggcctg accgaccctg cccaatcggc gcgtcgtcca ctaccgtcgg
    15301 ggcctaccgc gtacccgacc cccctcggag tgacgatgcg tgcacgcccc gtcctggcgg
    15361 ccgccctcgg cctggtccta ctcctcgctg tcggctgcgg cgaaccgcaa cgggaccccc
    15421 agcaggccgc ggcacccgcc ccgactgcgg cggcgagtcc atcaccggtg accaccccgt
    15481 caccgagagc gactccgcgg ccggccacca aacccaagcc caagctgcgg ccgaagccca
    15541 ccacgctgcc cgcgggcctg cggcgcgcca ccggggtacg cgccgtcgcg ctgaccttcg
    15601 acgacgggcc ggacccggcc tggacgccga aggtcctcga ccagttgcgg gccgcccggg
    15661 tcaaggcgac gttctgcctg gtcggcaccc agatacgcaa gcacccggag ctggtcgccc
    15721 ggatggtccg tgagggtcac cagctctgta accacagctg gcggcacgac ctcgacctgg
    15781 gccgacggcc ggtggccgag atccgggccg acctggtccg gaccaacggg gccatccagg
    15841 ccgccgcgcc gggcgccaag gtgccgttct accgccagcc gggtggccgg tggaccccgg
    15901 aggtggtggc ggtggcccgg cagctcggca tgcggtcgct gcactggagc gtggacccgc
    15961 aggactgggc gaagccgacc gtcgccaccc tcgccgagcg ggtccacggc gccgcccgcc
    16021 ccggtgcgat cgtgctgatg cacgacggcg ggggcgatcg cagccacacc ctggccgcct
    16081 gcccgcacct gatcatcgac ttgaagcggc gcttcggcgt cgccccaccc cggtgacacc
    16141 cgatctgacc tgcgcttttg ccggcggctg cgccaccggc cataccggtt tggcccactg
    16201 accgggcatg gcatatgctt ctcatgcctc cggcggggcc ggatgggagc aagtccgctt
    16261 gaagttgcga gtgtgcaatg atggcggggc cgccctcatc gtctagcggc ccaggacgcc
    16321 gccctttcaa ggcggtagca cgggttcgaa tcccgttggg ggcacggtcc ggctcacgtc
    16381 ggatgcaaca ccagccaggt cctgtggagc agttggagtg ctcgccgccc tgtcaaggcg
    16441 gaggtcgcgg gttcaagtcc cgtcaggacc gccagcgccg acgccgcgtg aaccattgcg
    16501 cggcgttctg cgtatcggag catgtgaccc tttcggcgaa gaccccgcct tccgggtagc
    16561 atggaccgag caccacggcc aggtagctca gttggtacga gcgtccgact gaaaatcgga
    16621 aggtcggcgg ttcgaccccg cccctggcca catagccttt cgccgggcta caggagcgcc
    16681 gaccagcgga aacgccggtc ggcgctctgc ttttcgcccc gggatccccg ctgtccggtc
    16741 tgaccctcgt tgaccccgga attccgctgc tggccgctcc ttgtcgcacg tagatcgcac
    16801 ggccactcgt catcccggcc ggccgggaat cgtcgccgac ccctgctctg caaagatcaa
    16861 ggcttctgtc ggccagcgtc ggctactgca gctgacctgc ccggcctgtc ggttgccgcc
    16921 ggtcctcacc catacctgtc ggccggcttg gctgtacgga tggctgtacc gccgttgacc
    16981 atgacctgcg cattacgaga tcaaattgcc cgcgccgacg acctgggcac atgagcgtct
    17041 agcaggggaa atgcctctcg acatctcgca ccgctccccc actgtccgcc accggcttgc
    17101 ggactgaatg cggaccgcta gcggatcccc atccaggtac ccggcggatg cggcggaagg
    17161 cacaggtccg cgagcacccc gaagtgatcg ctcgcccaca ccccggcaac cggttcggcg
    17221 aacacccgcc ggcagtccac cacgtcgagg gtcggcccgt gcgggccgca ccggatgagg
    17281 atgtagtcga tccgccgccc ccggtccagc ggcatcagcc cggcccggat cagcggattg
    17341 cccggcgaga acgtgtgccc cggctcctca cggcgaaccg ccgtccagca gtcctcgtaa
    17401 cagacgctga tgccagccag cgactgccgg ccggtccaga accggacgct cgcagcgtcg
    17461 ggtgccgcat cgaagtcgcc cagcagcacc acgtgcggct cggtgtccgg accgtccggc
    17521 tcgagcggtt cggaccgtcg ctcggcaacc agttcctcga tgtaccgggc cgtccgcacc
    17581 gcctgcagtt cccgctcgta ctcggcgtcg tactgccagg ccggcttgtg atgcacgacg
    17641 agtaccggtc ccagcggcgg cggcaccgca acctccacca caacggcggc actccacggc
    17701 agcgccgcgg tgcgcggggc gacatgcaag tcgacaaccc cgacggtacg caccggccac
    17761 cggctgccca gcacggctcc gaccccgtcg gccgaccgcc ccgggtgcgg tacgaggtga
    17821 tagtccggcc cgagcaggcc accggcctcg tccaagtccc cgccgccagc cacctcctgc
    17881 agggccacca cgtccggccg cagctcgcgc agcccgtcaa cgagcaccgc ccgacggcgt
    17941 ggccagtcgg cgaagaacgg cgcaagggca ttcagggtga gcacccgcag gctggcagac
    18001 tcctcggaca tcccgtcatc ctgtgcccaa tgctgcgccg gcgacaaccg ggatagcgcc
    18061 tggagcttca gtttggaaga tcgcgctcaa cgagtcgtga tgcccgaaac gcctggggcc
    18121 ggcggcaaag ctcggtgcgg ctcgtgcccg ctcatgaccg ccgggcgcca cggttactgg
    18181 tccgtggatg gcccgcgccg gtacacggga ttctgtccat cgggataact tgccctatgc
    18241 ccgtcatcga tctgagtgcc gccagcccgc ccctcgtcgc ctcgcaggac gacaaaacca
    18301 cggttcgtgg cagcgctggc agtcctgggg ctcgggtgcc tcagcgggga gccgatgaac
    18361 ccaccaaagc ttgctcctga ggtgcggtgc gaatcatggc aggaggccct cgcgggcgag
    18421 tcggatcttg ttacctcttc gggaggggac gccacgagga tgcgcatggc cgtcactgtg
    18481 gattctgtaa ccggatgtgt cgtgtcggtg cggcactggc gtgaaccgga gcatccagtt
    18541 gactgaagcg gatctcctcg tcgggcagtc gtagaccatc cagcctcccc ggacggggac
    18601 aaggtggagc cccctaccgg acgtacgacc ttggccccgt ccggggaggc tggtagccct
    18661 tgtggtgccc gacgagggga tccacggctg atctctgagg agggccgggg ttcggggcag
    18721 agccccgagg tcttctgatc ctgtgacttc cgagcgtggc cggccggccc ggccgatgcc
    18781 ggccggaggt cgccagcagg ccggggccgg gccggcgcgg cccgcttgcg ggccgccttg
    18841 atgatctgac ctttcacgat ctgcggcaca ccgggcagac ccttgccgcg cagactggcg
    18901 cgaccctggc cgacctgatg aagcggctcg ggcactcatc catggcggcg gctcgccggt
    18961 acctgcacgc cgtcgatggg cgtgaccgtg agatcgccaa ggccctgtcg gaactcgccg
    19021 cgcacggtga tgtcgcacgg ctgccccggc acatcacgat gcggagctaa tcgcatgacc
    19081 gatcgcacgg cagcctccgg cggcttcctg acctgcggaa atgcgggtgc ctgaaaatcg
    19141 gaaggtcggc ggttcgaccc cgcccctggc cacatagcct ttcgccgggc tactagagcg
    19201 ccgaccagcg gaaacgccgg tcggcgctct tgctttgcgc cccggaggtc cacctgtccg
    19261 gtctgcccct cgttgacccc ggaatccctc tgctgcccgt cccttgttgc acggggactg
    19321 cacggcccct cgtcaccccg gtcggccggg agagcgtcgc cgacccctgc cttgcaaaga
    19381 tcaagcctgg tgtcgcctgg cgtcggctac tgcggttgac ctgctcgccc cgtcggctcc
    19441 cgtcgatgta tgaccggctt ggtctgctgg cttggcggca cggatggctg tacaaccaca
    19501 ccgttgcgtc tgacatgatc acgacgtgcc cgagcccgcc gacggcagtc cgcctacgga
    19561 gccgtctgcg ccgacggcgc ggaaagaact gcccgcacta ctcgtgctgc tgctcgcatc
    19621 ggccgttctg ctggcgctgt ctttcggctg tgccgccttg tggctgtaca actaactggc
    19681 cgtctgttgc gctggacccg gagcgtcagc ttggaagagc gcgctcaacc ggccgagatg
    19741 cccgaaacgc tgctcgctgc ggctggcccg gttacctttc gtgcccgctc ggaccgctgg
    19801 ccctcgcggc tactggcccg tggacggccc cgtgctggct tgcgatggct cattggctat
    19861 ggcggtatga cctttacctt gggccatcgt ctgctgggct cgtggcgagc aaggcgggat
    19921 cgtgacagct cgagggtcac tctgtgcagg ttgcgccgcc atgtgccgct gagcaggtcg
    19981 tccagcccca gcggggcgca gacgtgcagt gtctcggcag agtcgaggcg gacggcgaca
    20041 caggtagcgg tttcgggcca ggtggccacg gcatcggcta tggagcggag tgcgtcgaca
    20101 ggtccagtgc cgaacacgcg ctcgtaccag atgtgcaccg cggcttggtt ggtcgcctcc
    20161 cacgggaccg ccggctggtg gcgtcggaga agctcggttg ccgcgacgtc gttgcccggg
    20221 gtgagatcgt tcgcgtcgaa gaatgcaacg tcgacgtccc ggacgtcctg ggggttgaag
    20281 ccgcctccat accgttggct ccacacgaga tcccgcagaa cgcccgcccc tacccaagcg
    20341 tccggtagac cagcttcccg cacggtcgtc agcacgttga gtagccacgg acacgatgcg
    20401 atcaggtcgg ccaactcggc tgcctgcgga cctcgcggct cgactgctag cggcaatggt
    20461 ccccccaggt acgcccgcac cccggtacgg ccttgaggtc atcggcgcga gtcctcgatc
    20521 ggccggcgcc agatcgcttc ccactgggtc cactgtcctg gggcgggtgg tgtgcgctcg
    20581 atgctgtcag ctctgaactc gccaaaccca ccgaccccga cgtagcgccc ctcggccacc
    20641 gggtcctccg cgcgatatcc gaaggcatcc agtggcgcgc ccaactcgac gccgcaagac
    20701 gcgccgccgt cgcgcccgac gtttcggcaa caggctccga tgatgcgacc aggaaggagg
    20761 ccaccgggtg gagcagctgc tgacggtcaa ggaagctgcg gcccgcctcg gtacgaccga
    20821 gcgcttcccc cgccggctcc tcgccgagcg cccatccggt acgtcaagct cggcggtcac
    20881 cacgtccgca tccccgagac ggccctcgcg gagttcatcg ccgccggcac ggtagagccg
    20941 gtcaccgtcg cgtggtcggc cggtagggcg gtggcctgat ggcaagactg ccccggcaca
    21001 tcacgatgcg cagctagtcg atggctagtc ccgccgcagg acgaaccatc ccaccgcaac
    21061 gacgaggagg agcagtgcta ccgcgaacag ggcccttccg accaggtagg gcatggggat
    21121 gagaaacggt gcttgctgga tcagcaggct cgcgccgagc agcgcctggc tgccgccaat
    21181 gcggacgggc tgggaccgct ggctcgccgg caggcgcgca acccgcaccc aggccacggg
    21241 aaaccgtcgc gacacggcga cgcgcacgcc gagtacgagc acgaagaggc tgacgaccac
    21301 gatgacgaga cggccggcca gcagcaatgg gtccgtgtca ctcgggctca tgcggccatc
    21361 attgacgcgg tgtcaaggtc gcccttgaga gccggccgtc ccggcatccc gcccgtgttg
    21421 gcgtgatttg caattcgatc gccgaatctg gctatcatca cgctatggcg attgattgcg
    21481 ctcccgggct ggccccagca gtggcgttgt tccggtctct cggcgacccg acccggctgg
    21541 ccatcctgcg ccggatcgcg accggggagg ctcgggtggt ggacctgacc ggcgagctgg
    21601 ggttggcgca atcgacggtg tcgaagcacc tggcgtgtct tcgtgactgt gggctgatcg
    21661 actatcgggc cgagggccgc cagtcgttct acgccctgac gcggccggag ctcctggacc
    21721 tgctgcgctc ggccgaacag ctcctcgccg cgacgggcga ggcggtcgcc ctgtgcccga
    21781 cctacgggac acccgccgga tccccggcgg aggtgagcgc gtgagcgcct cgctcctgac
    21841 ctccgagcgt cgggcggtgc tgtcccggcg cagcctctgg ctggcctacg ccaccgccgg
    21901 ctacaacctg ctggagggcc tggtcgccat cgccgccggc gctgccgcct cgtcgacggc
    21961 gctgatcggc ttcggcctgg actcgttcgt cgaggtgtcc agcgcggccg tgctgatctg
    22021 gcagttccgc tctcgggtgc ccgaggatcg ggaacgcctg gcgctgcggc tcatcggcgc
    22081 atcgttcttc gccctcgcag cctgggtgac catcgacgcc gtccgctcgc tgctggcc
//
