LOCUS       NZ_LT607733            23030 bp    DNA     circular CON 17-OCT-2024
DEFINITION  Micromonospora echinofusca strain DSM 43913 chromosome I.
ACCESSION   NZ_LT607733
VERSION     NZ_LT607733.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora echinofusca
  ORGANISM  Micromonospora echinofusca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091445.1-RS_2024_10_17
            Annotation Date                   :: 10/17/2024 15:25:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,129
            CDSs (total)                      :: 6,059
            Genes (coding)                    :: 5,948
            CDSs (with protein)               :: 5,948
            Genes (RNA)                       :: 70
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 31 of 111
            Pseudo Genes (incomplete)         :: 94 of 111
            Pseudo Genes (internal stop)      :: 4 of 111
            Pseudo Genes (multiple problems)  :: 17 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:23:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4398685
            Orig. end                         :: 4421715
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607733.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23030
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="18"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23030
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23030
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13030](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13030
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    428..448
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            465..1724
                     /db_xref="GeneID:95803521"
                     /locus_tag="GA0070610_RS18585"
                     /old_locus_tag="GA0070610_3794"
     CDS             465..1724
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /db_xref="GeneID:95803521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286517.1"
                     /locus_tag="GA0070610_RS18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3794"
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="WP_089001221.1"
                     /transl_table=11
                     /translation="MFRVRTRRRPWALALAATAIIGATTALAVPVHPEPAQAAIGGITW
                     QDEFNAPAGTPVDQSKWRFDIGGGGWGNNERQYYTNSTSNAVHDGQGNLVITARRENPA
                     NYQCHYGRCEYTSARLLTAATFTQAYGRFEARIKIPRGQGIWPAFWMLGNDMGSVGWPN
                     AGEIDIMENIGREPNTVYGTIHGPGYSGGGGITGSRTIGQPLADAFHTYRVDWEPNSIV
                     WYLDGVEYHRVDPGRLGGNRWVFDHPFFMLLNVAVGGNWPGYPDASTQFPQQMLVDYVR
                     VSGYTSGGNPPGTTAIRGALSGRCIDIPSANPVDGAKLQIWDCNGTAAQAWTFASDGTI
                     RAMGKCMDPAWAGTANGTEVNLVTCNGNPAQRFTLNAAGDLVNLSANRCVDVRDRNTGN
                     GGKLQLWDCTGDANQKWSRA"
     gene            1982..2881
                     /db_xref="GeneID:95803522"
                     /locus_tag="GA0070610_RS18590"
                     /old_locus_tag="GA0070610_3795"
     CDS             1982..2881
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013732491.1"
                     /locus_tag="GA0070610_RS18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3795"
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_089003594.1"
                     /transl_table=11
                     /translation="MSTGLSLVLFPVALGIVMLGLGLTLTVADFRRVVAYPRAVIVSLV
                     CQMLVLPAICLGLVLAADLRPELAVGMLLLAASPGGSTASLYSHLFKGNVALNVTLTAI
                     NSVLALFTLPLVVNLSVAAFMGSDSSLGLQFDKVIQVFALVLIPIVIGMAVRRRRPGFA
                     ARMQRPVKILSVVVLAVVITGAVLGVKDEFAATIGAVGLVALLFNLLSLGIGYAAPRLL
                     RVGHRDSVASSFEIGVHNATLAITIALSPALLDNTDIAMPAAIYGILMFFTAAAFGLVA
                     ARRGSAAAEPTRPSATTV"
     CDS             3008..3190
                     /gene="allorf_4401693_4401875"
                     /locus_tag="allorf_4401693_4401875"
                     /protein_id="allorf_4401693_4401875"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAVRPGGPARRSRRGPSVAAQRRVCNRSPSAVGVSVRSWHGRPAE
                     RGTAMKRRPAGRRAS"
     CDS_motif       3008..3067
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAVRPGGPARRSRRGPSVAA"
                     /locus_tag="allorf_4401693_4401875_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3068..3190
                     /prepeptide="core"
                     /locus_tag="allorf_4401693_4401875_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="4290.9"
                     /monoisotopic_mass="4288.4"
                     /core_sequence="QRRVCNRSPSAVGVSVRSWHGRPAERGTAMKRRPAGRRAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVRPGGPARRSRRGPSVAA"
                     /leader_location="[3007:3067](+)"
                     /alternative_weights="4308.9"
                     /alternative_weights="4327.0"
                     /alternative_weights="4345.0"
                     /alternative_weights="4363.0"
                     /alternative_weights="4381.0"
     misc_feature    complement(3249..3262)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
     gene            3286..4863
                     /db_xref="GeneID:95803523"
                     /locus_tag="GA0070610_RS18595"
                     /old_locus_tag="GA0070610_3796"
     CDS             3286..4863
                     /codon_start=1
                     /db_xref="GeneID:95803523"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070610_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070610_3796"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_089001222.1"
                     /transl_table=11
                     /translation="MGIQMSLTARRTDRVFFDERVAWMLRVNRTLGADSRWVRAKRFAA
                     AFHGGSWERLVSESSVSRWETGGSRPSRAAISRYEEILELDPGEITATVDTIRRYVDTP
                     GSPSAAPTGAADGAATAELDALLDRALSREIMTGAGWDRLSALVTAAPHLVIAPRSARE
                     SVTQRLVSEMIIAHGRPWRQRFEALNRLFGHETLGREAVAACAALGADRENQIFIETVG
                     ALDGSRHPDASAHVLAQLNDPTNDRALRGALLACLRKVRFGHFTPGQRRMLVPRITDLL
                     RDPLFHADAVPVAAALQAGAGVPLGGPQVAPALPHPVPHVAATVARRVFDATTARLPRE
                     PQSDCRDATLLTLIGEILLHPASDRRLYAAMLVASTPYGPSLAAALAAEVVPTAADRVE
                     LNVRLLAGLRVLGGQAERPTVERLVTAARLPRSVVDAAAFAIGHLRGTSERGFWEAALR
                     HHARRWQARRDAPSAAALTGIVYSLGIAGQRQILADVRDDPGSPEPSRAAARWWLNLPG
                     HVYDSSRL"
     gene            complement(5000..6583)
                     /db_xref="GeneID:95803524"
                     /locus_tag="GA0070610_RS18600"
                     /old_locus_tag="GA0070610_3797"
     CDS             complement(5000..6583)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803524"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018253952.1"
                     /locus_tag="GA0070610_RS18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3797"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_089001223.1"
                     /transl_table=11
                     /translation="MTQQSIATSDKLDASVLKVAGVVVLGAIMSILDVTVVSVALPTFQ
                     REFDASYADVAWTMTAYTLALATVIPLSGWAADRFGTKRLYMIALTLFTIGSGLCANAD
                     TIGQLVGYRVLQGLGGGMLLPLGMTIMTRAAGPHRIGRLMAVLGIPMLLGPIGGPILGG
                     WLIDIASWHWIFLINLPIGAVALVYAALALPKDNPEPSESFDFVGMLMLSPGLALFLYG
                     VSSLPDAGTFADPEVWAPMLVGGVLVVAFVRYSFRPQHPLLDLRLFANRNLTIATVTMF
                     VFIIAFMGAGLLFPSYFLQIRGESTLTAGLLMAPQGLGAMVTMPVAGMLADRVPVGRTV
                     PFALVLIALGFFTFTQIDPQTSYVLLCGSLFVMGLGMGGTMMPIMTSALKTLKAHEVAR
                     GSTLVNILQQIGGSVGAATMSVILTSEMNGSRQIPGAVGPDGEPLTEAKVAIVVQQQPE
                     LADRFPVDPSLLSRGLDFAASSFATTFWVAFALVLLTFIPAAFLPRRREPSHLLDDEQP
                     GQAKAPVIIH"
     gene            complement(6785..9382)
                     /db_xref="GeneID:95803525"
                     /locus_tag="GA0070610_RS18605"
                     /old_locus_tag="GA0070610_3798"
     CDS             complement(6785..9382)
                     /codon_start=1
                     /db_xref="GeneID:95803525"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="GA0070610_RS18605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3798"
                     /product="AAA family ATPase"
                     /protein_id="WP_172896550.1"
                     /transl_table=11
                     /translation="MSTPWPLVGRRRELDRLLDSLDSGVTRCTLVTGEAGIGKSRLATE
                     VLAEAGRRGFLALRVTATPGWQSVPFGVLAQLVAQPVGPSVVEAFRDVAARLRAIAADR
                     PVLVVVDDVNWLDDASSALLERLVAGEGVRVLATARSEAVASPAVTALRRLGPVERVEL
                     AAMSQEETAELIQAMLGGPTDGLTLATVWQAVRGNPLFLREMLRGGRQTDALARRRGVW
                     TWRSTPLEHPHLSDLIAETLGQLGPDEIEALQYVAHGEPAPLPVVERLVPAQVAERLEE
                     RGLIELTTGEQRGLVRVAHPLYAEAARASTGALRTRRILRELADALEDTSPAQYEDHLR
                     VVSWRCEADLAVDDADLLAASESALLRRGARLAERLARRVASPRGARQLGRALVAQGRG
                     EEADEHLRRAYDSLDDPRDRAETAALRAVNLFWGLRRPGAASTVLADAASALPAAVHDG
                     LLTAVAAMAVFDGRIAEGRDAVTRLGQHPPRDPLLGMAGAPLLPYLLVFSGQPARAAAM
                     FDGDEVTFPQAWPTMRAATQALHVQALVMSGNLTQATESAEAYYLDAVDRGSADGVALL
                     ALMVGNCRYHRGRLGDALRWLREARALVDGHTLFPIRGYVLSVSAWFAAQAGAARDVRE
                     VRDELGGSFPTHSGPADFWGLAEAWTNVAEGRLAVAAGQLTALAAQARENGVRTIAAQA
                     LHLLSRVAPSTSAASALRQVADACDSPLFGLYADLAAALAGADPDALEELAATFGQRGY
                     TTLELEATIAAGAARRRRGDHRAANAHAARAEKLRGHCDAYWPAWCGRVESAPSPLTGR
                     EREICELAATGLDNTAIAHRLRLSVRTVENHLQRSYHKLGVRSRLELAGTFPA"
     misc_feature    9542..9558
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            9744..9923
                     /db_xref="GeneID:95805836"
                     /locus_tag="GA0070610_RS30575"
                     /old_locus_tag="GA0070610_3799"
     CDS             9744..9923
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95805836"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="GA0070610_RS30575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3799"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_157747182.1"
                     /transl_table=11
                     /translation="MSITDVVRAWKDEYHRGEASPDHPVGLVELSREELETVAGGMPPI
                     DGHTEKCCHCMSPC"
     CDS_motif       9744..9866
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSITDVVRAWKDEYHRGEASPDHPVGLVELSREELETVAGG"
                     /locus_tag="GA0070610_RS30575_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9867..9923
                     /prepeptide="core"
                     /locus_tag="GA0070610_RS30575_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="5.40"
                     /molecular_weight="1907.3"
                     /monoisotopic_mass="1905.8"
                     /core_sequence="MPPIDGHTEKCCHCMSPC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSITDVVRAWKDEYHRGEASPDHPVGLVELSREELETVAGG
                     "
                     /leader_location="[9743:9866](+)"
     gene            10001..13030
                     /db_xref="GeneID:95803526"
                     /gene="lanM"
                     /locus_tag="GA0070610_RS18615"
                     /old_locus_tag="GA0070610_3800"
     CDS             10001..13030
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803526"
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="GA0070610_RS18615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3800"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_089001226.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-75, bitscore:
                     253.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.6e-50, bitscore:
                     168.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGFLPALSLTERVPVDGAGAYPVSDRARWRLSRWRDSQAFATA
                     GAWQRRLAADACDEDVLLRLLDEPATVIAARLARPPEWSRRLQGLYSGPAPDDWRPERL
                     PGRPLDDALVVAAPLLADARRRVREAAAELAGPATPVDPAAVDALGLAELLDELVRLLS
                     RASVLELNVARVRGELTGPTPARRFATFFARMAQPRVALDFLTEYPVLARQLLTVVDAW
                     ASSTVEFLRRLHDDWAAIAPALGVRPDARLTGLTPAGDAHRGGRRVCVARFDDGSRVVY
                     KPRDLAVDARFQRLLGWLARRDAGLGLRPFGVLTRDGYGWTEFVAAAAPTSLPRYARHY
                     GSLLALLHALGAGDCHPGNVVGAGDTPVLVDLETLFTPALERGGGAADGGAVASCVLAV
                     GLLPAGEPPAGETGACNCAEWLGAGTDEMQLHVPGVHVGHGAPAAVEGVRPADLRAYEA
                     DVVAGFRRAYDVLSAETGALADRVRAFAGDEIRVVLRPTRTYARLQEALLHTDHLRDAL
                     DRDRLLDWLWVGVEELPVLAATIAAERADLAAGDTPLFTARVGSRDLWAGRDRRLPGAL
                     AGSALDGALRRIAGLGGADRERQVWLIRATFASLAETPDAPHAEVRWRPGPVPAEPSTF
                     RPLLAQAAEIGERVAAMAHGGTWFTFGPTAGARWAPVPMGAGLYDGLSGLALFYGYLGE
                     VTGHGDFTDLAAGIARRLNQRLRADGFPLTAVGAFNGWGGPCYAYGHLAALWGDDPTVH
                     AGLDLALTRLTALTDDAGDADVVDGLAGAVLAVLACGAEPQRAVDLARRLGDRLVAALP
                     AALRLGGLSHGAAGMATALFELWSVTGVERYAEAGRRALEFDRSLFDPATGNWADLRRP
                     GLLSNAWCHGAPGIGLSRVRIRRALSRRPLPQVDGLDAEIAVALRTTFGHGFGRNHSLC
                     HGDLGNLDLPLLAGADPAAVGAVVDGVLRDVAAHGWRCANPAGLDSPELMTGLAGIGYQ
                     LMRLAEPQRVPSLLTLAGAP"
     gene            13054..15273
                     /db_xref="GeneID:95803527"
                     /locus_tag="GA0070610_RS18620"
                     /old_locus_tag="GA0070610_3801"
     CDS             13054..15273
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803527"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="GA0070610_RS18620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3801"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_157747183.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.6e-29, bitscore:
                     99.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQMTDTDCGAACLAMILRHAGVRASLAGCRERLGVGRDGVSALA
                     LLDAARELGLRANAYRAAPEDLASLPMPLIAHWEGSHFVVVERRTRHGFSMVDPALGRR
                     TVPFAEAAEFLTGTVLVFTGRATTPGPAGRAGAARTPWLRRGYRLARGFLPALGTVLSV
                     SVALQLLGLALPLAMSTALDAILPARETGLLPYLGLAVLALALTQFGLAHLRSMLLVNL
                     QSRVDRELMTRLFAHLMSLPFRFFQQRSSGDLMQRLASSVLLREIVTTQVLTAAIDGAL
                     VLGYLAVLFAADTGFAVVALGIGLIQVCAVAAVNRRLLRLNHRQLTVQAEAESVLIEAL
                     SGIATIKSMGAEKQVYDHWLGRYSAALAVDRARSRLSSTVDNVAATVRLVGPLALLWLG
                     MYRIFADGMSLGDAMGLQMLALAVIAPLGSLVASAQVLQSVASTVQRLRDVFSARPEIE
                     DPSRLLSPTLRGKVEVRGLSFRYDGTGPYVLRDVSFTVQPGRTVAVVGASGSGKSTLAM
                     LLTGLYRPSGGQVRFDGVPLERIAPDALRRQFGVVFQESYLFRDSIRRNIALARPDLPM
                     ADVRRVARLAAIDADVEAMPLRYDTRVAERGQALSGGQRQRLSIARALAGEPVVLLLDE
                     ATSHLDVATERRVSQAVAALRCTQIVIAHRLSTVRHADEILVLDGGTVAERGSHDELLA
                     LGGRYAALVRAQLDGQAADDAAEVVRGSTGAPVEHEPVVTGGSHR"
     gene            15270..15839
                     /db_xref="GeneID:95803528"
                     /locus_tag="GA0070610_RS18625"
                     /old_locus_tag="GA0070610_3802"
     CDS             15270..15839
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803528"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014494.5"
                     /locus_tag="GA0070610_RS18625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3802"
                     /product="flavoprotein"
                     /protein_id="WP_089001228.1"
                     /sec_met_domain="Flavoprotein (E-value: 7.3e-29, bitscore:
                     98.7, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTLPFERVLVAACGSSGAMSLPQSLLAMRHALHLEVRVVMTGA
                     AATFVTPTALAAITGHPVTVEEAQGQPGVPHLDLTGWAQLVLVLPATANTLAKAAAGMA
                     DNLVTACVLASAAPVVFVPAMNVRMWEKPAVQRNVAQLRADGHGVVPPSRVLALSSGTA
                     TGIGVPGIETVLEWTVAHLASAASDA"
     gene            15832..16470
                     /db_xref="GeneID:95803529"
                     /locus_tag="GA0070610_RS18630"
                     /old_locus_tag="GA0070610_3803"
     CDS             15832..16470
                     /codon_start=1
                     /db_xref="GeneID:95803529"
                     /inference="COORDINATES: protein motif:HMM:NF022747.5"
                     /locus_tag="GA0070610_RS18630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3803"
                     /product="DUF3105 domain-containing protein"
                     /protein_id="WP_089001229.1"
                     /transl_table=11
                     /translation="MPDAIDREARATRWVAGLMALLGVGLAGWVAAPIARQRLAPPPPI
                     ASFGVPEAAAGCDPELTDPVSGKGVHVGRGARVAYLTVPPSSGPHYELPAPLRRFYLAG
                     DRPPVEVLVHNLEHGYTVVWYSADLPVPQVEALRGLAARLGADERTAKFVAAPWDASYG
                     RFPPGRRVGISRWGATAGYRLLCGSVSGAVIERFLAAHPATDSPEPEGA"
     gene            complement(16493..18121)
                     /db_xref="GeneID:95803530"
                     /locus_tag="GA0070610_RS18635"
                     /old_locus_tag="GA0070610_3804"
     CDS             complement(16493..18121)
                     /EC_number="1.3.8.4"
                     /GO_function="GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803530"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015179.1"
                     /locus_tag="GA0070610_RS18635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3804"
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="WP_089001230.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.2e-16, bitscore:
                     57.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.4e-25, bitscore:
                     88.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHEVFNQVPPLVGHDAADDPALLDGLDREGAGWAAAELHELGR
                     LGGGEQAIEQGRLANEHPPVLRTHDRHGNRVDEVEFHPAWHELMRTAVTHGLHAAPWAD
                     DRPGAHVARAAKFYTWRPDAGHGCPISMTYAAVPALRHAPELAARYEPLLTATSYDFGL
                     RAPLAKRGLLAGMSMTEKQGGSDVRANTTTARPEPDGTYRLLGHKWFTSAPMCDVFLTL
                     AQAPGGLTCFLVPRVLPDGTRNPMRLMRLKDKLGNRSNASAEVEYEHAVAWRVGDEGRG
                     VRTIIDMVNLTRLDCVIGAAAGMRQGVITAAHHATHRQAFGRYLVEAPLMRNVLADLAV
                     ESEAATVLMMRLAGATDRSARGDAAETAFKRLALAVGKYWVCKRWPAHAAEALECLGGN
                     GYVEESGMPRLFRESPLNSIWEGSGNVAALDVLRALAREPEVMAAFQAEVAAAAGADAR
                     LDAAVRRVRAELVDPDDVELRARRVVERLALVLQGALLVRHGHPAVADAFCASRLDGDH
                     GQAYGTLPRGVDFAAIIARAVPEVG"
     gene            complement(18118..18717)
                     /db_xref="GeneID:95803531"
                     /locus_tag="GA0070610_RS18640"
                     /old_locus_tag="GA0070610_3805"
     CDS             complement(18118..18717)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803531"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078470.1"
                     /locus_tag="GA0070610_RS18640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3805"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_089001231.1"
                     /transl_table=11
                     /translation="MVYRSTERVQARLSASRQRIIAAALEIMAEHGYAGCSVAAVAERA
                     GLATGSVYRHFPTKADLVAEVFRTASQREVDTVARAAAREDTVAERVTAVIETFSGRAL
                     RSPRLAYALLAEPADPAVDAERLVFRRAYAELIAGHVAQGVANGELPPQDPELTATALV
                     GALAEAMVGPLAAGVAGPRTIAHLITFLHRALGVSP"
     gene            18850..19596
                     /db_xref="GeneID:95803532"
                     /locus_tag="GA0070610_RS18645"
                     /old_locus_tag="GA0070610_3806"
     CDS             18850..19596
                     /codon_start=1
                     /db_xref="GeneID:95803532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283330.1"
                     /locus_tag="GA0070610_RS18645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3806"
                     /product="hypothetical protein"
                     /protein_id="WP_089001232.1"
                     /transl_table=11
                     /translation="MTPDPTDVNRRLDAALAGVAAAFRDMTAHRRETNCECHWGSAEEL
                     ALLKTPDVPLDEDLLRRTYWTTDWRYPGPLLRRILPPVTRRLAAGEVESLSGMDPLSRL
                     FVMGRWLDWPAAQRDAVREFLDAWWQHTLVDPGAKVPAHEALAFVAEVTGQLAPWLNTW
                     AQLLAGPTARRMLAAAADEWMSDLLGDRLPWSSWRDEEDTPCLALSMWVLRHAPPALRE
                     HDASGELCDLVRLLALPHADRWGGRG"
     gene            complement(19856..20296)
                     /db_xref="GeneID:95803533"
                     /locus_tag="GA0070610_RS18650"
                     /old_locus_tag="GA0070610_3807"
     CDS             complement(19856..20296)
                     /codon_start=1
                     /db_xref="GeneID:95803533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287086.1"
                     /locus_tag="GA0070610_RS18650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3807"
                     /product="hypothetical protein"
                     /protein_id="WP_089003595.1"
                     /transl_table=11
                     /translation="MKRLFSTLMALVTIASVMVIGAPAAQAAGSCSGTIIYSQVQSSGL
                     GELVIYYNSSNGGTNSACFYHRGAAYGKSAPTFVQIYRCAERSGEGAHCTRSGSADTDS
                     GDFSYHAGPVGVTGVASYCVEAVGYIGWAGERHQIYSRRQGC"
     misc_feature    20331..20346
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.79"
                     /tool="antismash"
     gene            complement(20572..21234)
                     /db_xref="GeneID:95803534"
                     /locus_tag="GA0070610_RS18655"
                     /old_locus_tag="GA0070610_3809"
     CDS             complement(20572..21234)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803534"
                     /inference="COORDINATES: protein motif:HMM:NF024698.5"
                     /locus_tag="GA0070610_RS18655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3809"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_089001233.1"
                     /transl_table=11
                     /translation="MSDVQVRPTTRERHIDEAARIWAEATAARDGATEVAPLRLARPLI
                     QAVLDGTPRSLLLVALDAGRVVGFAAVEPVPADGSTAEIRYLGVEPAAWGRGVGRQLLR
                     AAPAHLAAAGFARAELGVYVDNPRAVSLYEAAGWLPHGEAVPHPRSGRLEQRYRLDWDD
                     SRQDAGEATPPPPTTDLRQSHDVAHAIAATALGRDPGPMTTADSLSHTTSTSAPTSS"
     gene            21562..22383
                     /db_xref="GeneID:95803535"
                     /locus_tag="GA0070610_RS18660"
                     /old_locus_tag="GA0070610_3810"
     CDS             21562..22383
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95803535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788616.1"
                     /locus_tag="GA0070610_RS18660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_3810"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_089001234.1"
                     /transl_table=11
                     /translation="MSQRRDVPDGRAGAARADPEPEVAQAFDRLVEEGDVRLARPWPAL
                     IVTGLLGGIDVGTGVLAYLLVLDATGQKLLAGLAFGIGFVALLLARSELFTENFLVPVT
                     AVAARRNSLAALGRLWAVTLTGNLLGGWLVAWLITRALPGLRDTATSAGTHFAALGVNL
                     HSFTLAVLAGLVITLMTRMQHSTESLGVRLVPALLFGALLAGGELFHSVLDSILMFTAL
                     TAGRAPFGYLDWLGALGWSVLGNIVGGVGLVAFLRMARVPQELARERARNR"
     misc_feature    complement(22745..22760)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
ORIGIN
        1 agccggctga tcagcaactg gaacaaccgc tgcatcgacg tgccgaactc caacttctcc
       61 gacggggtgc ccctgcagac ctggacctgc aacggcaccg ccgcgcagtc ctggaccttc
      121 accggcggca ccctgcgtac gcagaacaac aagtgcatgg acgtggcctg gggctccacc
      181 gccaacggcg cgacgatcca gatcgccaac tgcagcggca acccggccca gcagttcgtc
      241 ctctcggcgg ccggcgacct ggtcaacccg caggcgaaca agtgcgtcga catcaaggag
      301 tggaacaact ccgacggcgc ccgcctgcac ctgtgggact gcgtcggcgg cgccaaccag
      361 aagtggcggc gcggctgacc cggtcccgcc gccgggtcac cgccgctcgt cccgccgtcg
      421 ccgcgcgaga cgtcgcgccg gcgcagttgc caaggaggtc ctacatgttc agagtccgta
      481 cccgtcgacg gccgtgggcg ctcgccctcg ccgcgaccgc gatcatcggt gccaccacgg
      541 ccctcgccgt gccggtccac cccgaaccgg cgcaggccgc catcgggggg atcacctggc
      601 aggacgagtt caacgcgccg gccggcacgc ccgtcgacca gagcaagtgg cgcttcgaca
      661 tcggcggcgg cggctggggc aacaacgagc ggcagtacta caccaacagc acgagcaacg
      721 ccgtccacga cggccagggc aacctggtga tcaccgcccg ccgggagaac ccggccaact
      781 accagtgcca ctacggccgg tgcgagtaca cctcggcccg gctgctcacg gcggccacgt
      841 tcacccaggc gtacggccgc ttcgaggccc gcatcaagat cccccggggt cagggcatct
      901 ggccggcgtt ctggatgctc ggcaacgaca tgggcagcgt gggctggccg aacgcgggcg
      961 agatcgacat catggagaac atcggccggg agcccaacac cgtctacggc accatccacg
     1021 gccccggcta ctcaggcggc ggcggcatca ccggcagccg caccatcggc cagccgctcg
     1081 ccgacgcctt ccacacctac cgggtggact gggaaccgaa ctcgatcgtc tggtacctgg
     1141 acggcgtcga gtaccaccgg gtggacccgg gtcggctcgg cggcaaccgg tgggtgttcg
     1201 accatccgtt cttcatgctc ctcaacgtgg cggtgggcgg gaactggccc ggctaccccg
     1261 acgcctccac gcagttcccg cagcagatgc tcgtcgacta cgtacgcgtc tcgggctaca
     1321 cctcgggggg caacccgccg ggcaccacag cgatcagggg cgcgctcagc ggtcgctgca
     1381 tcgacatccc gagcgccaac ccggtcgacg gggccaagct tcagatctgg gactgcaacg
     1441 gcaccgccgc gcaggcctgg acgttcgcct ccgacggcac gatccgggcg atgggcaagt
     1501 gcatggatcc ggcctgggcc ggcacggcga acggcaccga ggtcaacctc gtcacctgca
     1561 acggcaaccc ggcacaacgc ttcacgctca acgccgccgg tgacctggtc aacctcagcg
     1621 cgaaccgctg cgtcgacgtg cgcgaccgca acaccggcaa cgggggcaag ctgcaactgt
     1681 gggactgcac cggtgacgcc aaccagaagt ggtcgcgcgc ctgacggaac ccacgcgggt
     1741 gacggcaccc gtcggcgacc cgcccagcgg cggggtcggc cgaggcaccc ggcctcgacc
     1801 ggccccgccg cctgctgtcc actctcgcac cgggcgggta gggcgacacg gggacctgct
     1861 gtggatgctg ccgcaccgat ggccgccggg cccgcccggt tgcgcacgtg aggaggtgtc
     1921 ggaagcgcca tcgagatgtg aggatccggt ggaccttggc gtacgcgatc aggaggccgc
     1981 cgtgagtacc ggtttgtcgc tcgtgctctt ccctgtcgcg ttgggcatcg tgatgctcgg
     2041 cctcggcctc accctgaccg tggccgactt ccgccgcgtc gtcgcctatc cccgggcggt
     2101 gatcgtctcc ctggtctgcc agatgctggt cctgccggcc atctgcctcg gcctggtgct
     2161 cgccgccgac ctgcgcccgg aactggccgt cgggatgctg ctgctggccg cctccccggg
     2221 cggcagcacg gccagtctct acagccacct gttcaagggc aacgtcgcgc tcaacgtcac
     2281 cctgaccgcc atcaactcgg tgctcgccct gttcacgctg cccctggtcg tcaacctctc
     2341 cgtcgccgcg ttcatgggtt cggacagctc gctcggcctc cagttcgaca aggtgatcca
     2401 ggtcttcgcc ctggtgctca tcccgatcgt gatcggcatg gccgtccggc gccgtcgccc
     2461 cgggttcgcc gcgcgcatgc agcgacccgt gaagatcctc tccgtcgtgg tcctcgccgt
     2521 cgtgatcacc ggcgcggtgc tcggcgtcaa ggacgagttc gccgccacca tcggcgcggt
     2581 cggcctcgtc gccctgctgt tcaacctgct cagcctgggc atcgggtacg cggcgccgcg
     2641 gctgctgcgc gtcgggcacc gggactccgt cgcctcgtcg ttcgagatcg gcgtccacaa
     2701 cgccaccctg gccatcacga tcgcgctcag tcccgccctg ctcgacaaca ccgacatcgc
     2761 catgccggcc gcgatctacg gcatcctgat gttcttcacc gccgccgcct tcggcctcgt
     2821 cgccgcgcgc cggggcagcg ccgccgccga gcccacccgg ccgtcggcca cgacggtgtg
     2881 accggcgcgc tgcgcgcccg cgtacgggaa gcgagggctt cccgcgggta gccggggacc
     2941 caccggagtt cgcagcgcct ctcccgctcc ggggacggag cggcgcgtcg ctcgacggtg
     3001 cccaccggtg gccgttcgac ccggtgggcc ggcacgccgg agccgtcggg gtccgtccgt
     3061 tgcagcccag cgtcgcgtgt gcaatcgatc accctccgcg gtcggcgtct ccgtacgctc
     3121 ctggcacggt cgtcccgccg agagaggaac cgccatgaag cgtcggccag cggggcgtcg
     3181 agcgtcctga cggcgcggag ccggcgagtg tcgcccttcc gggtgtcccg ccggctccct
     3241 cgtcgctcgt agactcgaac caggccgggc agggccacgg aggcgatggg catccagatg
     3301 tcgctgacag ctcgacgtac ggaccgcgtc ttcttcgacg agcgtgtggc gtggatgctg
     3361 cgggtcaacc gcaccctcgg cgccgacagc cggtgggtca gggccaagcg cttcgcggcg
     3421 gccttccacg gtggttcgtg ggagaggctg gtcagcgaga gcagcgtgtc gcggtgggag
     3481 accggcggca gccgcccgag ccgcgccgcc atcagccggt acgaggagat cctcgaactc
     3541 gatccgggcg agatcaccgc gacggtcgac acgatccggc gctacgtcga cacccccgga
     3601 tccccgagcg cggcgcccac cggcgccgcg gacggcgccg ccacggccga actcgacgcg
     3661 ctgctcgacc gcgccctgtc ccgggagatc atgaccggcg ccgggtggga ccggctctcc
     3721 gcgctggtca cggccgcccc gcacctcgtc atcgccccga ggtccgcccg ggagagcgtc
     3781 acccagcgcc tcgtcagcga gatgatcatc gcgcacggtc ggccgtggcg gcagcgcttc
     3841 gaagccctca accggctgtt cggccacgag acgctggggc gggaggcggt cgccgcctgc
     3901 gcggcgctgg gcgccgaccg ggagaaccag atcttcatcg agaccgtcgg tgccctcgac
     3961 ggcagccggc accccgacgc cagcgcccac gtgctcgcgc aactgaacga cccgacgaac
     4021 gaccgtgcgc tgcggggtgc gctcctcgcc tgtctccgca aggtgcggtt cgggcacttc
     4081 acgcccgggc agcgccggat gctggtgccc cggatcaccg atctgctgcg ggatccgctc
     4141 ttccacgccg acgccgtccc ggtcgcggcc gccctccagg cgggcgcggg tgtcccgctg
     4201 ggcggcccgc aggtcgcccc ggcgctgccc cacccggtcc cgcacgtggc cgccaccgtc
     4261 gcccgccggg tcttcgacgc cacgaccgcg cggctgccgc gcgagccgca gtccgactgc
     4321 cgcgacgcga cgctgctcac gctgatcggt gagatcctgc tccatccggc cagcgaccgg
     4381 cgcctctacg cggcgatgct cgtcgcctcc accccgtacg gcccgtcgct cgccgccgcc
     4441 ctggcggccg aggtcgtgcc caccgccgcc gaccgcgtgg aactcaacgt ccggctgctc
     4501 gccggcctgc gggtgctcgg cggccaggcc gaacggccga cggtcgagcg cctcgtcacc
     4561 gcggcccggc taccgcgaag cgtcgtcgat gccgccgcgt tcgcgatcgg gcacctgcgg
     4621 ggcaccagcg agcgggggtt ctgggaggcc gcgctgcggc accacgcgcg tcgctggcag
     4681 gcccggcgcg acgcgccgtc ggccgccgcg ctcaccggca tcgtctacag cctcggcatc
     4741 gccggacagc ggcagatcct ggcggacgta cgcgacgacc cggggtcacc tgaaccgagc
     4801 cgggccgcgg cccgttggtg gctcaacctg cccggccacg tctacgacag ctcacgcctc
     4861 tgagaacagc tcacgcctct gagccgggcg ggcaccggcg ccacctcgac gaggcggact
     4921 cccccgccgg acgcccgacc cccgcagcgt tgccaggggc cgggcgtccg gaccgacctt
     4981 ccggggcccg ggtgacgcgt cagtggatga tgacgggggc cttcgcctgc cccggctgct
     5041 cgtcgtcgag caggtgcgac ggctcacgcc ggcggggcag aaacgcggcc gggatgaacg
     5101 tgagcagcac cagcgcgaac gcgacccaga acgtggtggc gaaggaactg gcggcgaagt
     5161 cgagcccacg ggagagcagc gacgggtcga ccgggaaccg gtcggcgagc tccggctgct
     5221 gctgcacgac gatggcgacc ttcgcctcgg tcagcggctc accgtccggg ccgacggcgc
     5281 cggggatctg ccgggagccg ttcatctcgc tggtgaggat caccgacatc gtggcggcgc
     5341 cgacggagcc accgatctgc tggaggatgt tgaccagggt ggagccgcgc gccacctcgt
     5401 gggccttcag ggtcttcagc gccgaggtca tgatcggcat catggtgccg cccatgccga
     5461 ggcccatgac gaacagcgac ccgcagagca gcacgtacga cgtctgcggg tcgatctggg
     5521 tgaaggtgaa gaacccgagg gcgatgagca ccagcgcgaa cggcacggta cgaccgacgg
     5581 ggacccggtc ggccagcatc cccgccaccg gcatggtcac catcgcgccg aggccctgcg
     5641 gcgccatcag caggccggcg gtcagcgtcg actcgccgcg gatctgcagg aagtagctgg
     5701 ggaacagcag gccggcgccc atgaacgcga tgatgaacac gaacatggtc accgtggcga
     5761 tggtgaggtt gcggttggcg aacagccgca ggtcgagcag ggggtgctgg ggccggaagg
     5821 agtagcgcac gaaggcgacg acgagcacgc cgccgaccag catgggagcc cacacctcgg
     5881 ggtcggcgaa cgtgccggcg tcgggcagcg aggagacgcc gtagaggaag agggcgagcc
     5941 ccggcgagag catcagcatt ccgacgaagt cgaacgactc ggagggctcg gggttgtcct
     6001 tcggcagcgc cagggcggcg tagacgagcg ccacggcacc gatcggcagg ttgatcagga
     6061 agatccagtg ccagctcgcg atgtcgatca gccagccgcc gaggatcggc cctccgatgg
     6121 gcccgagcag catcgggatg ccgaggacgg ccatcagccg gccgatccgg tgcgggcccg
     6181 ccgcccgggt catgatcgtc atgccgagcg gcaggagcat gccgccgccg aggccctgga
     6241 gcacgcggta gccgaccagt tgcccgatcg tgtcggcgtt ggcgcacagc cccgacccga
     6301 tcgtgaacag cgtcagggcg atcatgtaga gccgcttggt gccgaaccgg tcggcggccc
     6361 agccgctgag cgggatcacc gtggccagcg cgagcgtgta ggccgtcatg gtccaggcga
     6421 cgtcggcgta cgacgcgtcg aactcgcgct ggaaggtcgg caacgcgacg ctgacgaccg
     6481 tcacgtcgag gatcgacatg atcgcgccga ggacgacgac cccggccacc ttgagcaccg
     6541 aggcgtcgag tttgtccgag gtcgcgatgg attgctgtgt cacgaattct cctgaagtcc
     6601 ccgttgtggc cggcgccggg ccatgcctcg acctgtcacc tgccgagcag tgtccgcagg
     6661 cagactaacg agcgacaccg acgatcggcc gacgattttc gaccggcagg aacggcgggt
     6721 gccgaccggc ggaagcggcg acccgtcccg gcggtgacgt cggcggcgtc ccggcggcgc
     6781 gcggctacgc cgggaacgtg cccgccagtt cgagccggct gcgcaccccc agcttgtggt
     6841 acgagcgctg gaggtggttc tccaccgtgc gcaccgacag gcgcagccgg tgggcgatcg
     6901 cggtgttgtc cagccccgtg gcggccagct cgcagatctc gcgttcccgg ccggtcaacg
     6961 ggctcggcgc ggactcgacc cgcccgcacc aggccggcca gtacgcgtcg cagtgcccgc
     7021 gtagcttctc ggcgcgggcg gcgtgggcgt tggcggcgcg gtggtcgccg cgccggcgcc
     7081 gggccgcgcc ggcggcgatc gtcgcctcca gctccagggt ggtgtatccc cgctgcccga
     7141 acgtcgccgc caactcctcc agcgcgtcgg gatccgcccc cgccagcgcc gcggccaggt
     7201 cggcgtagag cccgaagagc ggactgtcgc aggcgtcggc gacctgacgg agcgccgagg
     7261 ccgccgaggt ggacggcgcc acccgggaca gcaggtgcag cgcctgcgcg gcgatggtgc
     7321 gtacgccgtt ctcgcgggcc tgcgcggcca gcgcggtgag ctgcccggcc gcgacggcga
     7381 ggcgcccctc ggcgacgttc gtccaggcct cggcgaggcc ccagaagtcg gcgggcccgc
     7441 tgtgcgtggg gaagctccca cccagctcgt cgcggacctc ccggacgtcg cgcgccgcac
     7501 cggcctgcgc ggcgaaccag gcgctgacgg acaggacgta gccccggatg ggaaacagcg
     7561 tgtgcccgtc gacgagggca cgcgcctcgc gcagccagcg cagcgcgtcc cccaggcgcc
     7621 cccggtggta gcggcagttg ccgaccatca gggcgagcag ggccacgcca tcggcggagc
     7681 cgcggtcgac cgcgtccagg tagtaggcct ccgccgactc cgtggcctgg gtcaggttcc
     7741 ccgacatcac cagcgcctgc acgtgcaggg cctgggtggc ggcgcgcatg gtgggccagg
     7801 cctgcgggaa ggtgacctcg tcgccgtcga acatcgcggc ggcgcgggcc ggctgaccgg
     7861 agaagaccag caggtagggc aggagcgggg cgccggccat gcccagcagc gggtcgcgcg
     7921 gcgggtgctg gccgagccgg gtgacggcgt cgcgcccctc ggctatccgg ccgtcgaaga
     7981 cggccatcgc ggcgacggcg gtcagcagcc cgtcgtgcac ggcggcgggc agcgccgacg
     8041 ccgcgtcggc gagcacggtg ctggcggccc cgggccggcg cagcccccag aacaggttca
     8101 ccgcccgcag cgccgccgtc tcggcgcggt cgcgggggtc gtccagcgag tcgtacgcgc
     8161 ggcggaggtg ctcgtcggcc tcctcgccgc gcccctgcgc gaccagggcg cggccgagct
     8221 ggcgcgcgcc ccggggcgag gcgacccgcc gggcgagccg ctcggcgagg cgggccccgc
     8281 gtcgcagcag cgccgactcg gaggcggcca gcaggtccgc gtcgtcgacc gccaggtcgg
     8341 cctcgcaccg ccacgacacc acccgcaggt ggtcctcgta ctgggccggc gaggtgtcct
     8401 ccagggcgtc cgccaactcg cgcaggatgc ggcgggtacg cagcgcgccg gtgctcgccc
     8461 gggccgcctc ggcgtagagc gggtgcgcca cccggaccag gccgcgctgc tcgccggtgg
     8521 tcagctcgat gagcccccgc tcctccagcc gctcggcgac ctgcgccggg acgagccgct
     8581 cgacgacggg cagcggcgcg ggctcgccgt gcgccacgta ctgcaacgcc tcgatctcgt
     8641 cgggaccgag ctggccgagc gtctcggcga tgaggtcgct caggtgcggg tgttccagcg
     8701 gggtgctgcg ccaggtccac acgccgcgcc gtcgggcgag ggcgtcggtc tgccgcccgc
     8761 cgcgcagcat ctcccgcagg aacagggggt tgccgcgtac cgcctgccag acggtggcga
     8821 gggtcaggcc gtcggtgggc ccgccgagca tcgcctggat cagctcggcc gtctcctcct
     8881 ggctcatcgc cgccagctcc acccgctcga cggggccgag gcggcgcagg gcggtgacgg
     8941 ccgggctggc gaccgcctcg ctgcgggcgg tggcgaggac ccgcaccccc tcgccggcca
     9001 cgagccgctc cagcagcgcc gacgacgcgt cgtcgagcca gttcacgtcg tcgacgacga
     9061 cgaggacggg ccggtcggcg gcgatggcgc gcagcctggc ggccacgtcg cggaaggcct
     9121 cgacgaccga cggacccacc ggctgggcga cgagctgggc gagtacgccg aagggcacgc
     9181 tctgccagcc cggcgtcgcg gtcacccgca gcgccaggaa gccgcgccgc cccgcctcgg
     9241 ccagcacctc cgtggcgagg cggctcttgc cgatgccggc ctccccggtc accagggtgc
     9301 accgggtcac gccgctgtcg aggctgtcga gcagccggtc cagctcccgc cgccgcccga
     9361 cgagtggcca tggtgtggac aacgggtccc tccccacaag acgtctgccg tgacagacgc
     9421 tgtcagcggc gcacgaggtt gtcggccggg atgacggtag ggcaaccgcg atcgttgagt
     9481 accgaattcc gccggccctg agtagccccg ccggcacccg cgtacgcatg ctgacctgcg
     9541 catgtagtta tctttcagcg cgccccccgt atgtggcgtc aggtttcaga caccgtcgcg
     9601 cacgtcgcca cacgcggtcg gcggtgaccg gttcgcgact gcggtggagt agccgctact
     9661 caagccccgg cccgcgcccc cggccagtct cgaagggacg gaccgcggca tccggccgcc
     9721 ggtcgcgacc aaggaggaac ctgatgtcga tcaccgacgt cgtccgtgcc tggaaggacg
     9781 agtaccaccg cggcgaggcg tcgcccgacc accctgtcgg cctggtcgag ctgagccgcg
     9841 aggagctgga gacggtcgcc ggcggcatgc cgccgatcga cgggcacacc gagaagtgct
     9901 gccactgcat gtcgccctgc tgacctgtcc atcacggcga ccgcgccgga gcccggcgag
     9961 ctgccgggct ccggccccgc cccgcacccg aggatcggcg atgaccgttg ggttcctacc
    10021 cgccctctcg ctcaccgagc gcgtcccggt cgacggggcc ggcgcgtacc ccgtctccga
    10081 ccgcgcccgc tggcggctct cccggtggcg cgactcgcag gccttcgcca ccgccggggc
    10141 ctggcagcgc cgcctcgccg ccgacgcgtg cgacgaggac gtcctgctgc gcctgctcga
    10201 cgagcccgcc acggtgatcg cggcccggct cgcgcgcccc ccggagtggt cgcgacgctt
    10261 gcagggcctg tactccgggc cggcccccga cgactggcgc ccggaacggc tgccgggccg
    10321 cccgctcgac gacgcgctgg tcgtcgccgc cccgctgctc gccgacgccc gccgccgcgt
    10381 gcgcgaggcc gcggcggagc tggccggccc cgccacgccc gtcgaccccg ccgccgtcga
    10441 cgcgctcggc ctcgccgagc tgctcgacga gctggtccgg ctgctcagcc gcgcgagcgt
    10501 gctcgagctg aacgtcgccc gcgtgcgcgg cgagctgacc gggccgacgc cggcgcggcg
    10561 cttcgccacc ttcttcgccc ggatggcgca gccccgcgtc gcgctggact tcctcaccga
    10621 gtacccggtg ctggcccgcc agctcctgac cgtggtcgac gcctgggcct cgtccaccgt
    10681 cgagttcctg cgccggctgc acgacgactg ggccgcgatc gcgccggccc tcggcgtacg
    10741 cccggacgcg cggctcaccg ggctcacgcc cgccggcgac gcccaccggg gcgggcggcg
    10801 ggtgtgcgtc gcccgcttcg acgacggctc gcgcgtggtc tacaagcccc gcgacctcgc
    10861 cgtggacgcc cgcttccagc ggttgctggg ctggctcgcc cggcgcgacg ccggcctggg
    10921 cctgcgcccc ttcggggtgc tgacccgcga cggctacggc tggacggagt tcgtcgccgc
    10981 cgccgcaccg acgtcgctgc cccgctacgc ccgccactac ggcagcctgc tcgccctgct
    11041 gcacgcgctg ggcgccggcg actgccatcc cggcaacgtg gtgggtgccg gcgacacacc
    11101 ggtgctcgtc gacctggaga ccctgttcac cccggcgctg gagcgcggtg gcggcgccgc
    11161 cgacggcggg gccgtggcgt cctgtgtcct cgccgtcggg ctgctgccgg ccggcgagcc
    11221 accggcgggc gagacgggtg cgtgcaactg cgccgagtgg ctcggcgcgg gcaccgacga
    11281 gatgcagttg cacgtacccg gcgtgcacgt cgggcacggg gcaccggccg ccgtcgaggg
    11341 cgtccggccg gcggacctgc gggcgtacga ggccgacgtc gtcgccggct tccgccgcgc
    11401 gtacgacgtg ctcagcgccg agaccggggc gctggccgac cgggtacgcg ccttcgccgg
    11461 cgacgagatc cgggtggtgc tgcgcccgac gcgcacctac gcccggctcc aggaggcgct
    11521 gctgcacacc gaccacctgc gcgacgccct cgaccgggac cggctgctgg actggctctg
    11581 ggtcggcgtg gaggagctgc cggtgctggc cgcgacgatc gccgccgaac gcgctgacct
    11641 ggcggccggg gacacgccgc tgttcaccgc ccgggtgggc tcgcgcgacc tgtgggccgg
    11701 ccgcgaccgg cggctgcccg gcgccctggc cggctcggcg ctggacgggg cgctgcgtcg
    11761 catcgccggc ctgggcgggg ccgaccggga gcggcaggtg tggctcatcc gcgccacgtt
    11821 cgcgtccctg gccgagacgc ccgacgcccc gcacgccgag gtccgctggc gtcccgggcc
    11881 ggtgccggcg gagccgtcga cgttccgtcc gctgctggcg caggccgccg agatcggcga
    11941 gcgggtcgcg gcgatggcgc acggcgggac gtggttcacg ttcggtccca ccgccggggc
    12001 ccgctgggcg ccggtgccga tgggggccgg cctctacgac ggcctgtcgg gcctggccct
    12061 gttctacggc tacctgggcg aggtcaccgg gcacggagac ttcaccgacc tggccgccgg
    12121 gatcgcccgc cggctgaacc agcggctgcg cgccgacggg ttccccctga ccgccgtcgg
    12181 ggcgttcaac ggctggggcg gcccgtgcta cgcgtacggc catctggccg ccctgtgggg
    12241 cgacgacccg accgtccacg ccggactgga cctggcgctc acccggctga cggcgctgac
    12301 cgacgacgcc ggcgacgccg acgtggtcga cgggctggcc ggcgcggtgc tcgcggtgct
    12361 ggcgtgcggc gcggagccgc agcgcgcggt cgacctggcg cgtcgcctcg gcgaccggct
    12421 cgtcgcggcg ctgcccgccg cgctccggct gggcggcctg tcgcacggcg ccgccgggat
    12481 ggcgacggcg ctgttcgagc tgtggagcgt caccggcgtg gagcgctacg ccgaggcggg
    12541 gcgccgcgcc ctggagttcg accgctcgct gttcgacccg gccacgggca actgggcgga
    12601 cctgcgccgg cccggcctgc tcagcaacgc ctggtgccac ggcgcacccg gcatcgggct
    12661 gtcgcgagtg cgcatccggc gggcgctgtc ccgccgcccg ctgccgcagg tcgacggcct
    12721 cgacgccgag atcgcggtgg cgctgcgcac cacgttcggg cacggcttcg gacgcaacca
    12781 cagcctgtgc cacggcgacc tcggcaacct cgacctgccc ctgctcgccg gggcggaccc
    12841 ggcggcggtc ggtgcggtcg tcgacggcgt gctgcgcgac gtggccgccc acgggtggcg
    12901 ctgcgccaac ccggccgggc tcgactcgcc ggagctgatg accgggctgg ccggcatcgg
    12961 ctaccagctg atgcggctgg cggagccgca gcgcgtcccg tcgctgctga ccctggcggg
    13021 tgccccgtga ggcggcgcgg ccgggtgccc gtcgtgttgc agatgaccga caccgactgc
    13081 ggcgccgcct gcctcgcgat gatcctgcgc cacgcgggcg tacgcgcctc gctcgccggg
    13141 tgccgcgaac gcctcggcgt gggccgcgac ggggtcagcg cgctggccct gctggacgcg
    13201 gcgcgggagc tggggctgcg cgccaacgcc taccgggcgg cccccgagga cctcgcgtcg
    13261 ctgccgatgc cgctgatcgc gcactgggag ggctcgcact tcgtcgtggt ggagcgccgc
    13321 acccggcacg ggttctcgat ggtggacccc gccctcgggc gcaggacggt gccgttcgcc
    13381 gaggccgccg agttcctcac cggcaccgtg ctggtcttca ccggccgcgc gacgacgccc
    13441 ggcccggccg gacgcgccgg ggccgcccgt acgccgtggc tgcgccgggg ttaccggctg
    13501 gcgcgggggt tcctgcccgc gctggggacc gtgctgtccg tctccgtcgc cctgcaactg
    13561 ctcggcctcg ccctgccgct ggccatgtcg acggccctcg acgcgatcct gccggcgcgg
    13621 gagaccgggc tgctgcccta cctcggcctg gcggtgctgg ccctggccct gacccagttc
    13681 gggctggcgc acctgcgctc gatgctgctg gtgaacctcc agtcgcgggt ggaccgggag
    13741 ctgatgaccc ggctgttcgc ccacctgatg agcctgccgt tccgcttctt ccagcagcgc
    13801 tccagcggcg acctgatgca gcggctggcg agcagcgtgc tgctgcgcga gatcgtgacg
    13861 acccaggtgc tgaccgccgc catcgacggc gcgctggtgc tcgggtacct cgcggtgctc
    13921 ttcgccgccg acaccgggtt cgccgtggtg gcgctgggga tcggcctgat ccaggtctgc
    13981 gcggtcgcgg ccgtcaaccg ccgcctgctg cggctgaacc accgccagct caccgtgcag
    14041 gcggaggcgg agagcgtgct catcgaggcg ctgtcgggca tcgccaccat caagtcgatg
    14101 ggcgccgaga agcaggtgta cgaccactgg ctgggccgct actcggcggc gctggcggtg
    14161 gaccgcgcac gcagccggct gtcgtcgacc gtcgacaacg tggcggcgac cgtacggctc
    14221 gtgggcccgc tggccctgct ctggctgggc atgtaccgca tcttcgccga cggcatgagc
    14281 ctgggcgacg cgatgggcct gcagatgctg gccctggccg tgatcgcccc gctgggctcg
    14341 ctggtcgcca gcgcgcaggt gctccagtca gtcgcctcga ccgtgcagcg gctgcgcgac
    14401 gtgttctccg cccggcccga gatcgaggac ccgtcgcggc tgctgtcgcc gacgctgcgc
    14461 ggcaaggtcg aggtgcgcgg gctcagcttc cgctacgacg gcacgggccc gtacgtgctg
    14521 cgggacgtct cgttcaccgt gcagccgggc cggacggtgg cggtggtcgg cgcctcgggc
    14581 agcggcaaga gcaccctggc gatgctgctg accgggctct accggcccag cggcggccag
    14641 gtccgcttcg acggggtgcc gctggagcgg atcgccccgg acgcgctgcg ccgccagttc
    14701 ggcgtggtgt tccaggagag ctacctgttc cgcgactcga tccggcgcaa catcgccctc
    14761 gcccggccgg acctgccgat ggcggacgtg cggcgggtcg cccggctggc cgccatcgac
    14821 gccgacgtcg aggccatgcc gctgcgctac gacacccggg tggccgagcg gggccaggcg
    14881 ctctccggcg ggcagcgcca acgcctctcc atcgcgcggg cgctcgccgg ggagccggtg
    14941 gtcctgctgc tcgacgaggc caccagccac ctggacgtgg ccaccgagcg ccgggtgagc
    15001 caggccgtgg cggccctgcg ctgcacccag atcgtcatcg cgcaccggct gagcacggtg
    15061 cgccacgccg acgagatcct cgtgctcgac ggcggcacgg tcgccgagcg cggcagtcac
    15121 gacgagctgc ttgcgctcgg cggcaggtac gcggcgctgg tccgcgcgca gctcgacggc
    15181 caggccgccg acgacgccgc cgaggtcgta cgcggcagca cgggagcacc cgtggaacac
    15241 gagccggtcg tcaccggagg gagtcaccga tgagcgtcac gttgccgttc gagcgggtcc
    15301 tcgtcgccgc ctgcggatcc agcggcgcca tgtcgctgcc gcagtcgttg ctggcgatga
    15361 ggcacgcgct ccacctcgag gtgcgggtgg tgatgaccgg ggccgccgcg acgttcgtga
    15421 ccccgacggc gctcgcggcg atcaccggcc acccggtgac cgtcgaggag gcccaggggc
    15481 agccgggtgt cccccacctg gacctgaccg gatgggcgca gctggtgctc gtactgcccg
    15541 ccacggccaa caccctggcc aaggcggcgg cggggatggc cgacaacctg gtcaccgcgt
    15601 gcgtgctggc ctccgccgcg cccgtggtgt tcgtccccgc gatgaacgta cggatgtggg
    15661 agaagcccgc cgtccagcgc aacgtggcgc agctgcgcgc ggacgggcac ggcgtcgtac
    15721 cgccctcgcg ggtcctcgcg ctcagctccg gcacggccac gggcatcggg gtgcccggca
    15781 tcgagaccgt gctggagtgg acggtggccc acctggcctc ggcggcctcc gatgcctgac
    15841 gcgatcgacc gggaggcgcg ggcgacgcgg tgggtggcgg ggctgatggc gctgctgggc
    15901 gtcggcctgg cgggctgggt ggcggcgccg atcgcgcggc agcggctggc tccgcccccg
    15961 ccgatcgcgt cgttcggggt gcccgaggcg gcggccggct gcgatccgga gctgacggac
    16021 ccggtgtcgg gcaagggcgt ccacgtcggg cggggcgccc gcgtcgccta cctcaccgtg
    16081 ccgccgtcgt cggggccgca ctacgaactg cccgcgccgc tgcgccggtt ctacctggcc
    16141 ggcgaccggc ccccggtgga ggtgctggtg cacaacctgg agcacggcta cacggtggtg
    16201 tggtactccg ccgacctgcc ggtgccccag gtggaggccc tgcgcggcct ggccgcccgg
    16261 ctcggcgccg acgagcggac cgccaagttc gtcgccgcgc cgtgggacgc ctcctacggc
    16321 cggttcccgc cggggcgccg cgtcggcatc agccgctggg gcgccaccgc cggctaccgc
    16381 ctgctgtgcg ggtcggtcag cggcgccgtc atcgagcgct tcctcgccgc ccacccggcg
    16441 accgactcgc ccgaaccgga gggggcgtga cggcggccgg cgccgccgcc ggtcagccca
    16501 cctcgggcac cgcgcgggcg atgatcgcgg cgaagtcgac gccgcggggc agcgtgccgt
    16561 acgcctggcc gtggtcgccg tcgagccgcg aggcgcagaa ggcgtcggcg acggcggggt
    16621 ggccgtggcg caccagcagc gcgccctgca ggaccagggc gaggcgctcg acgacgcggc
    16681 gggcccgcag ctcgacgtcg tcgggatcga ccagctcggc ccgaacccgg cgtacggcgg
    16741 cgtcgagccg ggcgtcggcg ccggccgcgg cggcgacctc ggcctggaac gccgccatga
    16801 cctcgggttc cctggcgagg gcgcgcagca cgtccagcgc ggcgacgttg ccggagccct
    16861 cccagatcga gttcagcggg gactcgcgga acagccgggg catgcccgac tcctcgacgt
    16921 agccgttgcc gcccaggcat tcgagggcct cggcggcgtg cgccggccag cgcttgcaga
    16981 cccagtactt gccgacggcg agggcgaggc gcttgaacgc ggtctcggcg gcgtcgccgc
    17041 gcgcggaccg gtcggtggcc ccggcgagcc gcatcatcag cacggtggcg gcctcgctct
    17101 cgaccgcgag gtcggcgagc acgttgcgca tcaggggcgc ctcgacgagg taccggccga
    17161 aggcctgccg gtgggtggcg tggtgggcgg cggtgatcac gccctggcgc atcccggccg
    17221 ccgcgccgat gacgcagtcc agccgggtca ggttgaccat gtcgatgatg gtgcgtacgc
    17281 cgcgcccctc gtcgccgacc cgccaggcga ccgcgtgctc gtactcgacc tcggcggagg
    17341 cgttggaacg gttgccgagc ttgtccttga ggcgcatcag ccgcatgggg ttgcgcgtgc
    17401 cgtcgggcag gacgcgcggc acgaggaagc aggtgagccc gcccggcgcc tgggcgaggg
    17461 tgaggaagac gtcgcacatc ggcgcggacg tgaaccactt gtgcccgagc aggcggtagg
    17521 tgccgtccgg ctcggggcgg gcggtggtgg tgttggcgcg tacgtccgag ccgccctgct
    17581 tctcggtcat cgacatgccg gccagcagtc cccgcttggc cagcggcgca cgcagcccga
    17641 agtcgtacga cgtggcggtg agcagcggct cgtagcgcgc ggccaactcc ggggcgtgcc
    17701 gcagcgccgg cacggccgcg taggtcatcg agatcgggca gccgtgcccg gcgtcgggac
    17761 gccaggtgta gaacttggcc gcccgcgcca cgtgcgcgcc gggccgatcg tccgcccacg
    17821 gtgcggcgtg caggccgtgc gtgaccgccg tgcgcatcag ctcgtgccag gcggggtgga
    17881 actccacctc gtcgacgcgg ttgccgtgcc ggtcgtgggt acgcagcacc ggcgggtgct
    17941 cgttggccag ccgcccctgc tcgatggcct gctcgccgcc gccgaggcgg cccagctcgt
    18001 gcagctcggc ggcggcccag ccggcgccct cgcggtcgag cccgtcgagc agggccgggt
    18061 cgtcggccgc gtcgtgaccg accagcggcg gaacctggtt gaagacctcg tgcgtcgtca
    18121 cggcgacact cccagcgcgc ggtggaggaa cgtgatcagg tgtgcgatgg tgcgcggccc
    18181 ggcgaccccg gcggccaggg gaccgaccat ggcctcggcc agggcgccga ccagcgcggt
    18241 ggcggtcagc tcgggatcct gcgggggaag ctcgccgttc gccaccccct gcgcgacgtg
    18301 gccggcgatc agctcggcgt acgcgcggcg gaagacgagc cgctcggcgt cgaccgccgg
    18361 gtcggccggc tcggcaagca gggcgtacgc caaccggggg gaccgcagcg cccggccgga
    18421 gaacgtctcg atgacggcgg tgacccgctc ggcgaccgtg tcctcccgcg ccgccgcgcg
    18481 cgccaccgtg tcgacctcgc gctgcgaggc cgtgcggaac acctcggcga ccaggtcggc
    18541 cttggtgggg aagtgccggt agacgctgcc ggtcgccaac cccgcccgct cggcgaccgc
    18601 ggcgacggag cagccggcgt acccgtgctc ggccatgatc tccagcgcgg cggcgatgat
    18661 ccgctgccgg gacgcgctca gccgagcctg cacgcgctcg gtgctccggt agaccacgcc
    18721 aaggattgaa ccatcgttca ctccttggcg gcaaggcgct cctggccggc ggaggaccgc
    18781 ccgcgacgcg gtctaggatc actctcttcg gcaggcgtac gccccggagt cctcgaaggc
    18841 ggtcccgccg tgacccctga tccgaccgac gtgaaccgcc gcctggacgc ggcgctggcg
    18901 ggcgtggccg ccgccttccg ggacatgacc gcccaccggc gggagaccaa ctgcgagtgc
    18961 cactggggca gcgccgagga actggcactg ctcaagaccc ccgacgtgcc gctcgacgag
    19021 gacctgctgc gccgcacgta ctggaccacg gactggcgct acccggggcc gctgctgcgc
    19081 cgcatcctgc ccccggtgac ccggcgcctc gcggcgggtg aggtggagtc gctctccggg
    19141 atggaccccc tgtcccgcct gttcgtgatg ggtcgctggc tggactggcc cgccgcgcaa
    19201 cgcgacgcgg tacgggagtt cctggacgcc tggtggcagc acaccctggt ggaccccggg
    19261 gcgaaggtcc ccgcccacga ggccctggcc ttcgtcgccg aggtcaccgg gcagctcgcc
    19321 ccttggctga acacctgggc gcagctgctg gccggcccga cggcgcggcg gatgctggcc
    19381 gcggcggccg acgagtggat gtccgacctg ctcggcgacc gcctgccctg gtcgagctgg
    19441 cgcgacgagg aggacacgcc gtgcctcgcg ctgtcgatgt gggtgctacg gcacgcgccg
    19501 cccgcgctgc gggagcacga cgcgtccggc gagctgtgcg acctcgtacg gctgctcgcc
    19561 ctcccccacg ccgaccggtg gggcgggcgc ggctgaggtc tgttccgcaa gccgtgactg
    19621 gctgcaccgg actcgacggg ccggcggtgt agtccccctc gcctcgatac cgcacaggca
    19681 ttttcatacc tcacaggtat cggcgttccg gcggcagcgg tccgtcagcc tcacgcgcct
    19741 tccacgtcct ccgtcagcca gaacgccatc gctgccacga acggcgacag gggcaccccc
    19801 gtctccggga ggtgcccctg tcgcggcggc cggtacgcgg cccgatgagc tgcggtcagc
    19861 agccctgccg tcggctgtag atctggtgac gctcgcccgc ccacccgatg tagccgactg
    19921 cctcgacgca gtaggacgcc acgccggtga cgccgaccgg gccggcgtgg tagctgaagt
    19981 cgcccgagtc ggtgtccgcg ctgcccgagc gggtgcagtg cgcgccctcg cccgagcgct
    20041 cggcgcagcg gtagatctgc acgaaggtgg gcgccgactt cccgtaggcc gcgccacggt
    20101 ggtagaagca cgcgctgttg gtgcccccgt tgctgctgtt gtagtagatc accagctcgc
    20161 cgaggcccga ggactgcacc tggctgtaga tgatcgtgcc cgagcaggag ccggcggcct
    20221 gcgcggcggg cgcgccgatc accatgaccg acgcgatggt caccagcgcc atcagggtcg
    20281 agaacagtct cttcatgatc accaagccta tccacagtcg actgtcgcct gttgtggatc
    20341 atgatcgcac gacgcggcct ccggcggtgc cccggcctag cgccaccagg ggcggtcgac
    20401 gacgagttcc tcaaggtcac ggacgttctc ggcgaccgcc cgcgcggggg tgtccgggcg
    20461 ttgcagcgcg acccggaggt ccgaggatag atagctcgcc tcacgcacct cgcactcctg
    20521 gcgcagggcc gccgggacgt ctccgcgagt ggcccgcggc gtggatgatc ttcacgacga
    20581 cgtcggcgcc gacgtagacg tggtgtgcga gaggctgtcg gccgtggtca tcgggccggg
    20641 gtcgcggccc agggccgtgg cggcgatcgc atgggcgacg tcgtgggact gtcgcaggtc
    20701 ggtcgtcggc ggtggcgggg tcgcctcacc cgcgtcctgg cgggagtcgt cccagtcgag
    20761 tcggtagcgc tgttcgaggc gaccgctgcg cgggtgcggg acggcctcgc cgtggggcag
    20821 ccagccggcg gcctcgtaca ggctcaccgc ccgcgggttg tcgacgtaga cgcccagctc
    20881 ggcacgggcg aaacccgccg ccgcgaggtg ggcgggggcg gcccgcagca actgccggcc
    20941 gacgccccga ccccaggcgg cgggttccac gccgaggtac cggatctcgg cggtcgagcc
    21001 gtccgccggc acgggctcga ccgccgcgaa accgacgacc ctaccggcgt cgagggccac
    21061 cagcaggagc gagcggggtg tgccgtcgag caccgcctgg atcagggggc gggcgaggcg
    21121 gagcggcgcg acctcggtgg cgccgtcgcg ggccgcggtc gcctccgccc agatccgggc
    21181 ggcctcgtcg atgtgccgtt cacgggtggt cggccgtacc tgcacgtcgc tcatcgacac
    21241 agtctgtcga tgcggcgtcc cggtggcgac ccggtttgtc gcgccgctcc gcgcgacgcc
    21301 ggccccacac agcgcgctac ggggcgacgg ggcgacgggg cgacggggca agcttccagg
    21361 cgatcacgcc ggccgcgacc agcaggacgg cggcgagggc gcgtcccacg cccagtcgaa
    21421 gccgccttcg gccgcccgac gcgtcagggc cgggatctcc cggccgacgg cggcgagtgg
    21481 ccgagcgccc tcagcccggt cctgccgggc gtgacccgcc ccgacaggag tagccggtgc
    21541 gggaacgggc agacgggggc ggtgagccag cgtcgcgacg ttcccgacgg ccgggccggt
    21601 gccgcgcgcg ccgaccccga gccggaggtg gcgcaggcgt tcgaccggct ggtcgaggag
    21661 ggcgacgtcc ggctcgcccg gccctggccg gcgctgatcg tcaccggcct gctcggcggg
    21721 atcgacgtgg gcaccggggt gctggcgtac ctgctggtcc tggacgccac cgggcagaag
    21781 ctgctggcgg ggctcgcgtt cggcatcggg ttcgtggccc tgctgctggc ccgcagcgag
    21841 ctgttcaccg agaacttcct ggtgccggtg acggccgtgg ccgcccgccg gaactcactc
    21901 gccgccctgg gccggctctg ggccgtcacg ctgaccggca acctgctggg cggctggctg
    21961 gtggcgtggt tgatcacccg cgcgttgccc gggctgcggg acaccgccac ctcggccggc
    22021 acccacttcg ccgcgctggg cgtgaacctg cactcgttca ccctggcggt gctcgccggg
    22081 ctggtgatca ccctgatgac ccggatgcag cactccaccg agagcctcgg cgtacggctg
    22141 gtgccggcgc tgctcttcgg cgcgctgctc gccggcgggg aactcttcca cagcgtgctc
    22201 gactcgatcc tgatgttcac cgcgctcacc gccggccggg cgccgttcgg ctacctggac
    22261 tggctcggcg ccctcggctg gtcggtgctg ggcaacatcg tcggcggggt gggcctggtg
    22321 gccttcctcc gcatggcccg ggtgccgcaa gagctcgccc gggaacgcgc ccgcaaccgc
    22381 tgaccggagg caccgcacgc cggcgggacg cggggaggcc gtacggaacg gcccggaacg
    22441 cgggcgagcc ccggtcgatg gtgcgatcga ccggggctcg tcacgtggta cgggtcaggc
    22501 gaggtcgaac cggtcgagtt ccatgacctt cgtccaggcc gcgacgaagt cggcgacgaa
    22561 cttctcgcgc gcgtcctggc tggcgtatac ctccgcgagg gcccgcagct gggagttgga
    22621 gccgaagacg aggtcgaccg cggtggcggt ccacttcacc tcgtcggtgg ccaggtcccg
    22681 gatctcgtag acgtgctcgt cggactgcga cgccttccac cgggtgcccg gggagagcag
    22741 gttggcgaag aagtcgttgg tgagcacgcc gggcttgtcg gtgaggacgc cgtgccggct
    22801 gccgccgacg ttggccccga gcgagcgcag gccgccgacg aggacggtca tctcgggcgc
    22861 ggtcaggttg agcatgtacg cccggtcgag cagcagcacc tccggctggg tcttctcgcc
    22921 cgcccgcagg tagttgcgga acccgtcggc gcgcggttcg aggacccgga aggactcgac
    22981 gtcggtctgc tcgaggctgg cgtcggtgcg gcccgggtgg aacggcacgg
//
