LOCUS       NZ_LT607733            20954 bp    DNA     circular CON 17-OCT-2024
DEFINITION  Micromonospora echinofusca strain DSM 43913 chromosome I.
ACCESSION   NZ_LT607733
VERSION     NZ_LT607733.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora echinofusca
  ORGANISM  Micromonospora echinofusca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091445.1-RS_2024_10_17
            Annotation Date                   :: 10/17/2024 15:25:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,129
            CDSs (total)                      :: 6,059
            Genes (coding)                    :: 5,948
            CDSs (with protein)               :: 5,948
            Genes (RNA)                       :: 70
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 31 of 111
            Pseudo Genes (incomplete)         :: 94 of 111
            Pseudo Genes (internal stop)      :: 4 of 111
            Pseudo Genes (multiple problems)  :: 17 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:23:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1514223
            Orig. end                         :: 1535177
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607733.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10954)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(213..228)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.05"
                     /tool="antismash"
     gene            361..750
                     /db_xref="GeneID:95801284"
                     /locus_tag="GA0070610_RS06995"
                     /old_locus_tag="GA0070610_1427"
     CDS             361..750
                     /codon_start=1
                     /db_xref="GeneID:95801284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462975.1"
                     /locus_tag="GA0070610_RS06995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1427"
                     /product="RidA family protein"
                     /protein_id="WP_088999260.1"
                     /transl_table=11
                     /translation="MTVTRLGSGGPWESVYGYCRVVRAGDLAWTAGCTSTVDGAVTHVG
                     DAAAQTAQALRIGLDALAEVGAEPGDVVRTRMYVTDRTYADEVGRAHNAVFGAVRPAAT
                     MVVVAGLLHPDHLVEVELEAFLGDR"
     gene            868..1311
                     /db_xref="GeneID:95801285"
                     /locus_tag="GA0070610_RS07000"
                     /old_locus_tag="GA0070610_1428"
     CDS             868..1311
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801285"
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="GA0070610_RS07000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1428"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_088999261.1"
                     /transl_table=11
                     /translation="MTDHLVLRRQVCFALYAASRALTDVYRPVLDEFGLTYPQYLVLLV
                     LWERDDAPTVSELGAALRLDSGTLSPLLKRLEGAGLVVRTRSARDERRVEVGLTGDGRA
                     LRQRMEEVPLRVARATGLTDAELVELRDTLTRVTETIHRQKEQ"
     gene            1317..1742
                     /db_xref="GeneID:95801286"
                     /locus_tag="GA0070610_RS07005"
                     /old_locus_tag="GA0070610_1429"
     CDS             1317..1742
                     /codon_start=1
                     /db_xref="GeneID:95801286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287575.1"
                     /locus_tag="GA0070610_RS07005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1429"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_089003333.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVDLDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRLVARKAKVDVSGSVVEAEVGIGANGSGGFGLAVTLLVDLPA
                     VERAAAEQVVEQAHQVCPYSNATRGNVEVALTVREAL"
     gene            1739..2740
                     /db_xref="GeneID:95801287"
                     /locus_tag="GA0070610_RS07010"
                     /old_locus_tag="GA0070610_1430"
     CDS             1739..2740
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (20-331). E-value: 1.3e-21.
                     Score: 68.9. Matches aSDomain:
                     nrpspksdomains_GA0070610_RS07010_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:95801287"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014399.1"
                     /locus_tag="GA0070610_RS07010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1430"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_088999262.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-22, bitscore:
                     77.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRNREIHLASRPQGWPTADNFRLVETDVPTPGPGQVVVRNRYM
                     SVDPYMRGRMNDVKSYVPPFALDAPLDGGAVGEVVAGGTEGLRPGDTVLHGLGWREYAL
                     LDAKAARKVDPDLAPVTAYLSVLGMTGLTAYAGLLDVAGMKPGETVFVSAAAGAVGSLV
                     GQIARLRGAGRVVGSAGSAAKVERLRALGFDAAFDYHDGPVRDSLKAAAPDGVDVYFDN
                     VGGDHLEAAISAMRVHGRAAICGMIAQYNDTEPPAAPRNLALVIGKRLTLRGFLVGDHG
                     HLRGEFVREMAGWLRDGKVSYDETVVDGIENAPEAFLGLLRGENLGKMLVRV"
     aSDomain        1799..2731
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070610_RS07010_PKS_ER.1"
                     /evalue="1.30E-21"
                     /label="GA0070610_RS07010_PKS_ER.1"
                     /locus_tag="GA0070610_RS07010"
                     /protein_end="331"
                     /protein_start="20"
                     /score="68.9"
                     /tool="antismash"
                     /translation="DNFRLVETDVPTPGPGQVVVRNRYMSVDPYMRGRMNDVKSYVPPF
                     ALDAPLDGGAVGEVVAGGTEGLRPGDTVLHGLGWREYALLDAKAARKVDPDLAPVTAYL
                     SVLGMTGLTAYAGLLDVAGMKPGETVFVSAAAGAVGSLVGQIARLRGAGRVVGSAGSAA
                     KVERLRALGFDAAFDYHDGPVRDSLKAAAPDGVDVYFDNVGGDHLEAAISAMRVHGRAA
                     ICGMIAQYNDTEPPAAPRNLALVIGKRLTLRGFLVGDHGHLRGEFVREMAGWLRDGKVS
                     YDETVVDGIENAPEAFLGLLRGENLGKMLV"
     CDS_motif       2177..2218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070610_RS07010_0001"
                     /evalue="5.80E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="GA0070610_RS07010"
                     /protein_end="160"
                     /protein_start="146"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GETVFVSAAAGAVG"
     gene            2836..3603
                     /db_xref="GeneID:95801288"
                     /gene="hisF"
                     /locus_tag="GA0070610_RS07015"
                     /old_locus_tag="GA0070610_1431"
     CDS             2836..3603
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801288"
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="GA0070610_RS07015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1431"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_088999263.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASASDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPGGGTPSGFEVTTHGGRRGTGLDAVEWA
                     RRGAELGAGEILLNSMDADGTKAGFDLELIGAVRRVVDVPVVASGGAGEVAHFAPAIGA
                     GADAVLAASVFHFGELTVAEVKDALRGAGHPVR"
     gene            complement(3733..4194)
                     /db_xref="GeneID:95801289"
                     /locus_tag="GA0070610_RS07020"
                     /old_locus_tag="GA0070610_1432"
     CDS             complement(3733..4194)
                     /codon_start=1
                     /db_xref="GeneID:95801289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018821166.1"
                     /locus_tag="GA0070610_RS07020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1432"
                     /product="hypothetical protein"
                     /protein_id="WP_088999264.1"
                     /transl_table=11
                     /translation="MGDCGWRWSDAWIFVSVVIASGAGRHRRAASSRRPEGVRLADVLS
                     TADHLNQAIPERHEVEAAVRRLVGAGLVSVTDGWFRITADGERLWRTRPNAGLATTVDT
                     VQGVLVRRHPPVSAEWHLDEADHAAAVQEYVVRSIPAPRRSPENRPRRD"
     gene            complement(4374..5027)
                     /db_xref="GeneID:95801290"
                     /locus_tag="GA0070610_RS07025"
                     /old_locus_tag="GA0070610_1433"
     CDS             complement(4374..5027)
                     /codon_start=1
                     /db_xref="GeneID:95801290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018832747.1"
                     /locus_tag="GA0070610_RS07025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1433"
                     /product="YitT family protein"
                     /protein_id="WP_088999265.1"
                     /transl_table=11
                     /translation="MTPIGNLRHRPARRLTQLYAGLVLYGVSMALMINSGLGLNPWDVF
                     HQGLSELTGLSFGTVTIAVGALVLLLWIPLRQRPGLGTVSNVLVIGLVVDAALALLPTG
                     GSLGVRGAMLVAGIVANGAATGLYLGARLGPGPRDGLMTGYVARRPGRSIRLVRTAIEV
                     TVLALGWLLGGTVGVGTVAYALAIGPLTQLFLPPFTVAGPRGPAPGPVTPLPTL"
     misc_feature    5010..5025
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.53"
                     /tool="antismash"
     gene            5086..6543
                     /db_xref="GeneID:95801291"
                     /locus_tag="GA0070610_RS07030"
                     /old_locus_tag="GA0070610_1434"
     CDS             5086..6543
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (126-463). E-value: 1e-27.
                     Score: 89.1. Matches aSDomain:
                     nrpspksdomains_GA0070610_RS07030_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GeneID:95801291"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="GA0070610_RS07030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1434"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_088999266.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-25, bitscore:
                     88.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGAQLARLLGQWHALPGRRRNPDYAALAGAVRGLLADGRL
                     PLGVRLPAERELAEALKISRTTVTAAYRELRESGHLASRRGAGSWTMLPGTHRVASTGL
                     WTPLDDRDMIDLGVAALAAPPELLPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAY
                     TDRGLPTSPDQIMVTNGTQHALDLVLRLALAPGGNVLVEAPSYPNALAALAARRARITT
                     HGLAVEEPGWDADLLLGGLRQARPKLAYLIPDFQNPTGHLMPAALRERVVATAHAVGTD
                     LVVDESFVDLPLDGTVLPPPTASFDRHSRVITIGGMSKPFWGGLRIGWVRASAPQVQRL
                     AAARVGVDMASPVLDQLVAVHLLADAPGIVAARQAQLTAQRDALLAALAQRLPEWRVTV
                     PHGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVE
                     AVGRIAAVRYDLDRGGRSQWREPAVIA"
     aSDomain        5464..6474
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070610_RS07030_Aminotran_1_2.
                     1"
                     /evalue="1.00E-27"
                     /label="GA0070610_RS07030_Aminotran_1_2.1"
                     /locus_tag="GA0070610_RS07030"
                     /protein_end="463"
                     /protein_start="126"
                     /score="89.1"
                     /tool="antismash"
                     /translation="LLPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAYTDRGLPTS
                     PDQIMVTNGTQHALDLVLRLALAPGGNVLVEAPSYPNALAALAARRARITTHGLAVEEP
                     GWDADLLLGGLRQARPKLAYLIPDFQNPTGHLMPAALRERVVATAHAVGTDLVVDESFV
                     DLPLDGTVLPPPTASFDRHSRVITIGGMSKPFWGGLRIGWVRASAPQVQRLAAARVGVD
                     MASPVLDQLVAVHLLADAPGIVAARQAQLTAQRDALLAALAQRLPEWRVTVPHGGVTLW
                     AELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVEAVGRI"
     gene            6630..7943
                     /db_xref="GeneID:95801292"
                     /locus_tag="GA0070610_RS07035"
                     /old_locus_tag="GA0070610_1435"
     CDS             6630..7943
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072131.1"
                     /locus_tag="GA0070610_RS07035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1435"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_231925938.1"
                     /transl_table=11
                     /translation="MGDARGIRWPRAILPSAPGSRTTRLELFYDLVFVFAFLNVTTATA
                     GNPTPRGLVQFLVVLALLWWCWSGFAVVGNVVRTDQGIAPLVGFAVSAAVFVLALSLPK
                     AFVDRPGGLPGPVVFAVCYFLVRATQVTVFLWAVRTDPAVRRRMPVLALPFLIATGLIL
                     AAAMVPQRLFDGTAEIALRLALWLAALGVEYGSGLVQQRAGWTVLSAGHWAERHALIIM
                     VALGESIIALGIGPGTTAALPLTWPVIIAAFLGIAVVAALWWAYFDTLALAMEQVLHRT
                     RERRTRAGLARDVYTYLHLPLITGVILFALGLKGLIHEGADPATPTWGVPLPGFDMLAL
                     FGGVALYLLTLVLLGSRMLGAARWPSIGGVVLLAALTPVATRLPELVALAMLAVAAMLT
                     VSAQTVVDAPRRRRVRQVALEEQLASEAEQTRWRGHHL"
     gene            complement(8036..9862)
                     /db_xref="GeneID:95801293"
                     /locus_tag="GA0070610_RS07040"
                     /old_locus_tag="GA0070610_1436"
     CDS             complement(8036..9862)
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 3.1e-88.
                     Score: 288.1. Matches aSDomain:
                     nrpspksdomains_GA0070610_RS07040_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:95801293"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="GA0070610_RS07040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1436"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_088999268.1"
                     /sec_met_domain="AMP-binding (E-value: 9.2e-88, bitscore:
                     293.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSIPDMFLKRVAASPDRDAFAHPAPDDSGPVWLNWEQM
                     ARRAKAVAAGLHGLGVGLENPVAILANTRLDWVIADLGIMCAGGATTTVYPTTEPDDAT
                     YIIADSGSRVLFAENPAQAAKIAGADLPALTHVVLFDGAADPAAAVPQLTLAELEEQGA
                     RALAAEPDLIDTLVAQIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     ENDLQYLWLPLSHSFGKTLLCGAIHVGLPTYVDGRVDKLVDLLSVIRPTLMCGAPRVFE
                     KVYNKAVTTAQAGGGAKAKIFAWGVRVGKEKVALEQAGRPVPTGLKLKYTVAEKLVFSK
                     LQARLGGRIRVLVSGAAPLSPEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGT
                     VGKAMGDLECRIDTDGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGY
                     LKITDRKKDLVKTSGGKYIAPSHIEGMFKATCPYTSQAVVIGQARNYCTMLVTLDPDAI
                     KGWAAGTPLEGRDYAEIVASPEAKAMVEGYVAELNAKLNRWETIKKVAILPRDLTIEDG
                     EITPSLKIKRRGVESNFAGEIEKLYAGTLAEL"
     aSDomain        complement(8450..9820)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GA0070610_RS07040_AMP-binding.1"
                     /evalue="3.10E-88"
                     /label="GA0070610_RS07040_AMP-binding.1"
                     /locus_tag="GA0070610_RS07040"
                     /protein_end="471"
                     /protein_start="14"
                     /score="288.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVAASPDRDAFAHPAPDDSGPVWLNWEQMARRAKAVAAGLHGL
                     GVGLENPVAILANTRLDWVIADLGIMCAGGATTTVYPTTEPDDATYIIADSGSRVLFAE
                     NPAQAAKIAGADLPALTHVVLFDGAADPAAAVPQLTLAELEEQGARALAAEPDLIDTLV
                     AQIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRENDLQYLWLPLSHS
                     FGKTLLCGAIHVGLPTYVDGRVDKLVDLLSVIRPTLMCGAPRVFEKVYNKAVTTAQAGG
                     GAKAKIFAWGVRVGKEKVALEQAGRPVPTGLKLKYTVAEKLVFSKLQARLGGRIRVLVS
                     GAAPLSPEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGTVGKAMGDLECRIDT
                     DGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGYLKITDRKKDLVKT"
     CDS_motif       complement(8546..8620)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070610_RS07040_0002"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="GA0070610_RS07040"
                     /protein_end="439"
                     /protein_start="414"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GEILVRGRPVMRGYHNLPEETAAAF"
     CDS_motif       complement(9248..9307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GA0070610_RS07040_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="GA0070610_RS07040"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     misc_feature    complement(9890..9905)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            complement(10001..10954)
                     /db_xref="GeneID:95801294"
                     /locus_tag="GA0070610_RS07045"
                     /old_locus_tag="GA0070610_1437"
     CDS             complement(10001..10954)
                     /codon_start=1
                     /db_xref="GeneID:95801294"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="GA0070610_RS07045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1437"
                     /product="terpene synthase"
                     /protein_id="WP_088999269.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-70, bitscore: 237.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFAVSALREPPFPERQHDATERVARESTEWALDHGLIGDGHRL
                     HRLRRADAAGLAGRACPESPVDGLRLLTDLISWLFVMDDACDEDGLGDSPTRLAPTVAA
                     LLDVLDGQGSPTDGPATVAGPLGEALADLCRRAHAAGGPAALLRFVGDVREYLLALLWE
                     AANREHGRVPGLAEYAQMRRHTGAVHPSFTLTELAGGTLPGAAHRTEPSLVALDLLAAD
                     LVCWCNDVFSYRKEHLTQPDVHNLVAVIAAGRADGDESAALRAAADRFNGALSAYLAAE
                     TALLATGDAGLRSALTARRNWIRATYDWSLRAARYA"
     gene            complement(11080..11709)
                     /db_xref="GeneID:95801295"
                     /locus_tag="GA0070610_RS07050"
                     /old_locus_tag="GA0070610_1438"
     CDS             complement(11080..11709)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="GA0070610_RS07050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1438"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_088999270.1"
                     /transl_table=11
                     /translation="MPRYARSEREALADLMQTLGPEAPTVNEGWDIRDLAAHLVLRERR
                     PDAAGGILLPPLRGYAERVRLRVAARPWPRLLDEVRRPPLWSPVSNPVTDELANTLEFF
                     IHHEDVRRARPGWLPRDLSAGLDAALWKRCAGLARLALRRFPADVFIQAPGYGELSVGR
                     GGEPVRVVGAPGELALFLSGRQRVSRVQIDGPATLSERLRDASLGM"
     gene            11857..13737
                     /db_xref="GeneID:95801296"
                     /locus_tag="GA0070610_RS07055"
                     /old_locus_tag="GA0070610_1439"
     CDS             11857..13737
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801296"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="GA0070610_RS07055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1439"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088999271.1"
                     /transl_table=11
                     /translation="MASRTSRDVLVRGLVVLGRAIREEPRIFAVAVSGSVLFGAMTVAS
                     AFVVGAVVGDVVVPAIERGAVGVGGLALAAVALFGISVLRVAGIFGRRLGAGYMQYRLQ
                     AAYRRRVTRRYLELPLAWHHRNATGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     ASLFVTDWALALVGLAVFPALFALNVAYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETDRFAARAGELRDSLVAVGRLRGVFDPLLETLPSLGTLAVLVVGAIRLR
                     QGEISVAELISVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVSRVLDATGEMPYGDTT
                     LDVSEPRPASLAFSGVRFGYEPAEAHLPGTEVLGEVSFTVPAGKIVALVGPTGSGKSTI
                     AALAVRLVDPLAGTVCLDGVDVRRLTAASLTGTAALVAQVPFVFDDTVRANVTLDRPGI
                     GDDDVWAALRLAEADGFVAALPEGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRSSAGEAGAPAASILVVAYRRATIALADEVVYLEQGRVVA
                     RGPHAELLATVPGYVDLVTAYEQAEVDHTKDETYDEVAPLTSGLEIEVDR"
     gene            13936..15663
                     /db_xref="GeneID:95801297"
                     /locus_tag="GA0070610_RS07060"
                     /old_locus_tag="GA0070610_1440"
     CDS             13936..15663
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801297"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018824279.1"
                     /locus_tag="GA0070610_RS07060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1440"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_089003334.1"
                     /transl_table=11
                     /translation="MRRGLALSPELRVGLAGTLGLALVYMVGRAAVPVAVQQGIDNGLV
                     GGLDLGVVWTVVAATAAVLVVTTICGYLMMRRLFTVSETALANVRIRAFRHVHDLSMLH
                     QQSERRGSLVSRVTSDVDQITQFLQWGGVILVINLGQLAVTTLVMFAYSWQLTLVVFAA
                     FLPAVFLIRLLQRRLAGAYGVVRQRTGALLGAIGESVVGAPVIRAYGIAGRTARRLDEA
                     IDGQRRAQQKAIRISIMGSSVGELAAGLALAGVVVLGVTLGADRTLSIGEVTAFLFLVT
                     LFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVEPDVADPGEQGRDLPAGPLDIRFAGVR
                     FAYPGGPPVLHDVSLEIPAKSRVAVVGETGSGKTTFAKLLTRLMDPTAGQVLLSGVPLE
                     RVRFASLRSRVVMVPQDGFLFDATVAENVRFARPELTDEQLAAAFTELGLADWLDGLPS
                     GLHTPVGERGEALSVGERQLVALARAYVADPDLLVLDEATSAVDPATEVRLQRTLDAVT
                     RGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHDELVRDPESVYGLLYASWLEQTR"
     gene            complement(15720..16331)
                     /db_xref="GeneID:95801298"
                     /gene="rpsD"
                     /locus_tag="GA0070610_RS07065"
                     /old_locus_tag="GA0070610_1441"
     CDS             complement(15720..16331)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801298"
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015561.1"
                     /locus_tag="GA0070610_RS07065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1441"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_088999272.1"
                     /transl_table=11
                     /translation="MTQPRPKARLSRALGIPLTRKCVRYVERRPYPPGVHGRQRRKTSD
                     YQVRLLEKQRLRHQYNVSETQLRHVFEEAARGAGKTGDGLVALLERRLDAVVHRAGLAR
                     SIYQARQLVAHGHFTVDGRKVDRPSYRLRPGQVVAVRERSRAALPVQLAATGANATEGP
                     GQPYLSVELAELRTTLLREPARHEVPVICDEQLVVQFYSR"
     misc_feature    16368..16386
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.62"
                     /tool="antismash"
     gene            16400..17161
                     /db_xref="GeneID:95801299"
                     /locus_tag="GA0070610_RS07070"
                     /old_locus_tag="GA0070610_1442"
     CDS             16400..17161
                     /codon_start=1
                     /db_xref="GeneID:95801299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441676.1"
                     /locus_tag="GA0070610_RS07070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1442"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_088999273.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPGIAHVAHRPGPHQVRHVTDPDGRVLLL
                     VPVVSDLAAALRPAGGDSEVALVLDVLDLPPAAGAPSLGRAWVSGWAARLDGDEERRAA
                     LDFAAVEPTGDLLDVGTRFRLHRFEVVEARWERGDTVRRIDPEAYAEAEADPLHAVEAE
                     LLTDLADHHGTEVAGYLCRQLGLADDAGDAAPRVVRIDRYGLLVTHGRPGARRRVRLAF
                     PRPLQCQAELTRLLHPLVGRHASSPRHADHA"
     gene            complement(17189..17797)
                     /db_xref="GeneID:95801300"
                     /locus_tag="GA0070610_RS07075"
                     /old_locus_tag="GA0070610_1443"
     CDS             complement(17189..17797)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801300"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183498.1"
                     /locus_tag="GA0070610_RS07075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1443"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_088999274.1"
                     /transl_table=11
                     /translation="MARRTGRRPGNPDTRQAILDAARAAFAERGFDAASIRAVAAAAEV
                     DPALVHHYFGSKDQLFLAAMHAPVDPAELLPRVLAGDRVGLGERLVRTFLGVWDSPAGT
                     AGVALLRSAVSNEWTARLLREFLVTQVLRRVLDQLDVDPAELPLRGSLVASQLIGLAMM
                     RHVVRLEPVASAAPETLVAAVGPTVQRYLTGDLAEVFAG"
     gene            complement(17811..18548)
                     /db_xref="GeneID:95801301"
                     /locus_tag="GA0070610_RS07080"
                     /old_locus_tag="GA0070610_1444"
     CDS             complement(17811..18548)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801301"
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="GA0070610_RS07080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1444"
                     /product="ABC transporter permease"
                     /protein_id="WP_088999275.1"
                     /transl_table=11
                     /translation="MNPRILAATTGRILRQLRHDRRTVALLLVVPSALLALVHSMYVDQ
                     PSTFDRVALVMLGFFPFVVMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFGYGIAFG
                     LAAVLQAAVATVVAYGVFGLDTAGNSGLVVLVAALNAVLAVALGLFCSAFARTEFQAVQ
                     FMPVVVVPQLLLCGLFVPRGEMAGWLQAVSDALPLSYAVEALQEVGAHAEPTGTMWRDV
                     AVVAGAAALALVLAAATLRRRSG"
     gene            complement(18545..19273)
                     /db_xref="GeneID:95801302"
                     /locus_tag="GA0070610_RS07085"
                     /old_locus_tag="GA0070610_1445"
     CDS             complement(18545..19273)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95801302"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020608815.1"
                     /locus_tag="GA0070610_RS07085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1445"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088999276.1"
                     /transl_table=11
                     /translation="MDEAIAVRDLVVERGGRRVLHGVSASVPRGVVTGLLGPSGSGKTT
                     LLRAVVGVQVVGAGSVTVLGRPAGSPELRHRVGYLTQAPSVYADLTVRENARYFAALHG
                     RGRAEADRAVAEVGLGSAAGQLVGTLSGGQRSRASLACALVGEPELLVLDEPTVGQDPV
                     LRADLWARFHAMAAAGTTLLVSSHVMDEAARCDRLLLIREGRLIADDTPDAVRAAAGTD
                     DLDEAFLRLIRAGAAGREAS"
     misc_feature    19570..19583
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.17"
                     /tool="antismash"
     misc_feature    complement(19571..19584)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.63"
                     /tool="antismash"
     gene            19656..>20252
                     /db_xref="GeneID:95805938"
                     /locus_tag="GA0070610_RS31325"
                     /pseudo=""
     CDS             19656..>20252
                     /codon_start=1
                     /db_xref="GeneID:95805938"
                     /inference="COORDINATES: protein motif:HMM:NF037778.5"
                     /locus_tag="GA0070610_RS31325"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATAHSDVDVDVLLAGAPYAARQAFLAEHGGRLTHV
                     SVAARDVRSWLARLGEPADWAFGLPVAAPARLLWADPHWRPRIDLPVLCQPAGEPQLEE
                     LIATLGKVAGARDADDHLGVRLAAADLARLCPSVLRLANPTVRVASRRGAFAAALDLPV
                     APPNYRDDLLLCLGLRPGSVGQLCAAAARLVAGVLP"
     gene            20433..20870
                     /db_xref="GeneID:95805939"
                     /gene="hisI"
                     /locus_tag="GA0070610_RS31330"
     CDS             20433..20870
                     /EC_number="3.5.4.19"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95805939"
                     /gene="hisI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183495.1"
                     /locus_tag="GA0070610_RS31330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="WP_089003335.1"
                     /transl_table=11
                     /translation="MPVPDAPVTGAHPSPQEPAADGTARSSRLDPAIAARLRRTPDGLV
                     AAVVRQHDSGEVLMVAWMDDEALHRTLTTGRATYWSRSRREYWVKGATSGHHQYVRAVA
                     LDCDGDALLVDVDQVGAACHTGHRTCFFTELPVGGEGAGAR"
ORIGIN
        1 cgaccgggtg gcgatcgggc tggacgtgcg gggccgtacc ctctcggccc ggggctggac
       61 ccgcgacggc ggcgacctgt tcgaggtgct ggagcggttg gacaaggcgg gcgcgacgcg
      121 ctacgtcgtc acggacatca ccaaggacgg cacaatgcgc gggccgaacc tggacctgct
      181 gcgcgaggtc tgcgcccgca ccgacgcccc ggtgatcgcc tccggcggcg tctccaccct
      241 ggacgacctg cgggcgctgg ccaccctgga gccgatcggg gtcgagggcg tgatcgccgg
      301 caaggccctg tacgcgggcg ccttcacggt ggcgcaggcg ctggaaaccc tggcgacggc
      361 gtgaccgtca cgcggctcgg ctcgggcggc ccgtgggagt cggtgtacgg ctactgccgg
      421 gtggtccggg ctggcgacct ggcctggacg gccggctgca cctccacggt ggacggcgcg
      481 gtcacccacg tcggcgacgc ggcggcgcag accgcccagg cgctgcggat cgggctggac
      541 gcgttggccg aggtgggcgc ggagcccggc gacgtggtgc gcaccaggat gtacgtgacg
      601 gaccgcacgt acgccgacga ggtcggccgg gcgcacaacg cggtcttcgg cgcggtccgt
      661 ccggcggcca cgatggtggt ggtggccggt ctgctccacc cggaccacct ggtggaggtg
      721 gagttggagg cgtttctcgg cgaccgctga gccggcgggc gcggcggtgg cggcggtgca
      781 gtcgcggccc gccgtggcgg cggtggcgcg ggtcaccgcg cgccccggtc ggttgtgtgc
      841 aatctaattg cgcgctacgt ttttccggtg accgaccatc tggtgctgcg ccggcaggtg
      901 tgcttcgcgc tctacgccgc gtcgcgcgcc ctcaccgacg tctaccggcc cgtcctcgac
      961 gagttcggcc tgacctaccc gcagtacctg gtgctgctgg tgctctggga gcgcgacgac
     1021 gcccccacgg tctccgagct gggcgccgcg ctgcggctgg attccggcac gctctcgccg
     1081 ttgctcaagc ggttggaggg ggcggggctg gtcgtccgga cgcgctcggc gcgcgacgag
     1141 cggcgggtgg aggtgggcct gaccggcgac gggcgggccc tgcggcagcg gatggaggag
     1201 gtgccgctgc gggtcgcccg cgccacgggc ctcaccgacg cggagctggt cgaactgcgc
     1261 gacaccctca cccgggtcac cgagacgatc caccgacaga aggagcagtg accatcatgc
     1321 aggtgctcta caccgcgtcc gcccgggcca ccggggacgg tcgggacggc cacgtccgca
     1381 cctccgacgg caccgtcgac cttgacctgg ccgtgccgaa ggagatgggt ggcgccggcg
     1441 gcgccgccaa ccccgagcag ctcttcgcgg ccggttacgc cgcctgcttc cactcggcgc
     1501 tgcgcctggt cgcccgcaag gcgaaggtcg acgtctcggg ctcggtcgtc gaggccgagg
     1561 tcggcatcgg cgccaacggc agcggcggct tcgggctggc cgtcaccctc ctggtcgacc
     1621 tcccggccgt cgagcgggcc gccgccgagc aggtcgtcga gcaggcccac caggtctgcc
     1681 cctactcgaa cgcgacccgc ggcaacgtcg aggtcgccct caccgtgcgc gaggcgctgt
     1741 gagcacccgc aaccgcgaga tccacctcgc ctcccgcccg cagggctggc cgacggccga
     1801 caacttccgc ctcgtcgaga ccgacgtgcc cacccccggc ccgggccagg tcgtggtccg
     1861 caaccggtac atgtcggtcg acccgtacat gcggggacgc atgaacgacg tcaagtcgta
     1921 cgtgccgccg ttcgcgctcg acgcgccgct ggacggcggg gcggtcggcg aggtcgtggc
     1981 cggtgggacc gagggcctgc ggcccggcga caccgtgctg cacggcctcg gctggcgcga
     2041 gtacgcgctg ctcgacgcga aggccgcccg gaaggtcgac cccgacctcg ccccggtcac
     2101 cgcctacctg agcgtgctgg gcatgaccgg cctgaccgcg tacgccgggc tgctggacgt
     2161 cgccgggatg aagcccgggg agacggtctt cgtctccgcc gccgccggcg cggtcggcag
     2221 cctggtcggc cagatcgcca ggctgcgcgg cgcggggcgc gtggtcggca gcgcaggctc
     2281 ggcggccaag gtcgaacggc tgcgggcgct cggcttcgac gccgcgttcg actaccacga
     2341 cgggccggta cgcgactcgc tgaaggccgc cgcgcccgac ggcgtcgacg tctacttcga
     2401 caacgtcggc ggggaccacc tggaggcggc gatctccgcg atgcgggtgc acggtcgggc
     2461 cgcgatctgc ggcatgatcg cgcagtacaa cgacaccgag ccgccggccg cgccgcgcaa
     2521 cctggcgctg gtcatcggca agcggctcac cttgcgcggc ttcctggtcg gcgaccacgg
     2581 ccacctgcgc ggcgagttcg tccgcgagat ggccggctgg ctgcgggacg ggaaggtctc
     2641 ctacgacgag acggtcgtcg acggcatcga gaacgccccg gaggcgttcc tcggcctgct
     2701 gcgcggcgag aacctcggca agatgctcgt ccgggtgtga gcgggggcgt cgctgccggc
     2761 gcccccggga ccccgacgcg gtggccggcc tcaccggccg gtcaccgccg gggccgggaa
     2821 ggataggctc gcggcatgac ggtggcggta cgggtcatcc cgtgtctgga cgtggacgcc
     2881 ggtcgtgtgg tcaagggggt caacttcctc gacctgcgcg acgccggcga cccggtggag
     2941 ctggcggcgg cgtacgaccg cgccggcgcg gacgagctga ccttcctcga cgtcaccgcc
     3001 tccgccagcg accggggcac gatgctcgac gtggtccgcc gcacggcgga gtcggtcttc
     3061 atcccgctca ccgtcggcgg tggcgtccgg caggtcgccg acgtcgacac cctgctgcgt
     3121 gccggcgcgg acaaggtcgg ggtgaacacc gccgccatcg cccgccccga gctgatcgcc
     3181 gagatcgccg accgcttcgg ccggcaggtg ctggtgctct cgctcgacgt ccggcgggcg
     3241 cccgggggcg gcacgcccag cgggttcgag gtgaccaccc acggcggtcg acgcggcacg
     3301 gggctcgacg cggtcgagtg ggcccgtcgc ggcgccgaac tgggcgcggg cgagatcctg
     3361 ctcaactcga tggacgccga cggcaccaag gccgggttcg acctcgaact catcggcgcg
     3421 gtgcgccggg tggtcgacgt gccggtggtg gccagcggcg gcgccggcga ggtggcgcac
     3481 ttcgcgccgg cgatcggcgc cggcgcggac gcggtgctcg ccgccagcgt cttccacttc
     3541 ggcgagctga ccgtcgccga ggtcaaggac gcgctgcgcg gcgccgggca ccccgtgcgc
     3601 tgaccgtcgc cgcaccggac acccgtgcgc tggccctccg ccgccgcacc ggacacccgt
     3661 gcgctgaccg tccgccgcgt tggcagcccg accgggcggc tggccggccg ccgggcgcgg
     3721 cggcacccgg tgtcagtcgc ggcgtgggcg gttctcgggc gagcgccgcg gcgccgggat
     3781 cgaccgcacc acgtattcct ggacggcggc ggcgtggtcg gcctcgtcca ggtgccactc
     3841 cgcgctgacc ggggggtgcc gccgtaccag cacgccctgc acggtgtcca cggtggtggc
     3901 gagcccggcg ttcggccggg tgcgccagag gcgctcaccg tcggcggtga tccggaacca
     3961 gccgtcggtg acgctgacca gcccggcccc gacgaggcga cggaccgccg cctccacctc
     4021 gtgccgctcg gggatcgcct ggttgaggtg gtcggcggtg gagagcacgt cggcgaggcg
     4081 tacgccctcg gggcggcggc tggacgccgc gcggcggtgc cgtcccgcac cactggcgat
     4141 caccaccgac acgaagatcc aggcatcgct ccagcgccat ccgcagtccc ccatgcgagg
     4201 attctgccgg gcgtggcgtc cgaagggaac accggcgtcg ggcccgcgtc tccgggacag
     4261 gggtcacccg ggacgtggct cggggtggtg cggggcgggc cgggcagcgg cgcgacgggc
     4321 gtccgcgccg acctcgatca cgccgaactg gtcggccccg gggcgggatc cgctcagagc
     4381 gtggggagcg gcgtgaccgg gcccggggcg gggcccctcg gcccggcgac ggtgaacggc
     4441 ggcaggaaga gctgggtcag cgggccgatg gccagcgcgt aggcgaccgt gccgacgccc
     4501 acggtgccgc cgagcaacca gcccagcgcc agcaccgtga cctcgatggc ggtgcggacg
     4561 agccggatcg agcggccggg ccggcgggcg acgtagccgg tcatcagacc gtcgcggggg
     4621 cccggcccga ggcgggcgcc gaggtagagg cccgtcgccg ccccgttggc gacgatgccg
     4681 gcgaccagca tcgcgccccg tacgcccagc gacccgccgg tcggcagcag tgcgagcgcc
     4741 gcgtccacca ccagcccgat caccaggacg ttgctgaccg tgccgaggcc ggggcgctgg
     4801 cgcaggggta tccagagcag cagcaccagc gcgccgaccg cgatggtgac ggtgccgaag
     4861 gagaggccgg tcagctcgga caggccctgg tggaacacgt cccacgggtt caggccgagc
     4921 cccgagttga tcatgagggc catgctcacg ccgtacagga cgaggcccgc gtagagctgg
     4981 gtgagccgcc gcgctggacg gtgtcggaga ttgccaatcg gtgtcaccca tgccacgcta
     5041 aaggccaatt cgcgcagcgt aagagccaat ccgggaggag tggccatgac cagtcaggtt
     5101 cggggtgctc aattggcccg gctcctcggt cagtggcatg cccttcccgg ccgccgccgc
     5161 aaccccgact acgccgccct ggccggcgcc gtacgcgggc tgctcgccga cggccgactg
     5221 ccgctgggcg tacgcctgcc cgccgagcgg gagctggccg aggcgctgaa gatcagccgg
     5281 accacggtca cggccgcgta ccgggagctg cgggagagcg ggcatctcgc gagccggcgg
     5341 ggcgccggca gctggacgat gctccccggc acccaccggg tggcgagcac cgggctctgg
     5401 accccgctgg acgaccgcga catgatcgac ctcggggtcg ccgcgctcgc cgcgccgccc
     5461 gaactgctgc cggcagcccg cgcggcggcc gaggacctgc cccgctacct gggcggcgcc
     5521 ggctaccacc cgaccggcat catcgagctg cgcgaggcgg tggcccgcgc ctacaccgac
     5581 cggggcctgc ccacctcgcc cgaccagatc atggtcacca acggcaccca gcacgccctc
     5641 gacctggtgc tccggctggc cctcgccccc ggcgggaacg tgctggtcga ggcgcccagc
     5701 tacccgaacg cgctggccgc gctcgccgcc cggcgggccc ggatcaccac ccacgggctg
     5761 gccgtcgagg agcccggctg ggacgcggac ctgctgctcg gcggcctccg gcaggcccgg
     5821 cccaagctgg cctacctgat cccggacttc cagaacccga ccggtcacct gatgccggcg
     5881 gcgcttcggg agcgggtggt ggccacggcg cacgccgtcg gcaccgacct cgtcgtcgac
     5941 gagtcgttcg tggacctgcc gctggacggg accgtgttgc ccccgccgac cgccagcttc
     6001 gaccggcact cccgagtgat caccatcggc ggcatgagca agccgttctg gggcggcctg
     6061 cgcatcggct gggtccgggc ctccgccccg caggtgcagc ggctcgccgc cgcccgcgtc
     6121 ggcgtcgaca tggccagccc ggtcctggac cagctggtcg cggtccacct gctcgccgac
     6181 gcgccgggca tcgtcgccgc ccggcaggcc cagctgaccg cccagcgcga cgcgctgctc
     6241 gccgcgctcg cgcagcgcct gcccgagtgg cgggtcaccg tcccgcacgg cggggtgacc
     6301 ctctgggccg agctcgacgg gccgatctcc agcgcgctgg cccgggccgc cgaggaggtc
     6361 ggcgtacgcc tggcgcccgg tccccgcttc ggcctggacg gcacgctgga gcgcttcctg
     6421 cggctgccgt tcaccctgcc ggccgccgac ctggtcgagg cggtcggtcg catcgccgcc
     6481 gtccgctacg acctggaccg gggcggccgg tcgcagtggc gggaaccggc ggtcatcgcc
     6541 tgagggccgg gccggcgtgc cggccggaac tcgcggcccc gtcggtcaat cgcgcctgcg
     6601 cgacgccccg cggctgggag actgcgcagg tgggggacgc gcgggggatt cggtggccgc
     6661 gcgcgatcct gccgagcgca ccgggctccc gcaccacccg gctcgaactc ttctacgacc
     6721 tcgtcttcgt cttcgccttc ctcaacgtga ccacggcgac ggccggcaac ccgaccccgc
     6781 gagggctggt ccagttcctg gtggtgctcg ccctgctctg gtggtgctgg agcggcttcg
     6841 ccgtggtggg caacgtggtc cgcaccgacc aggggatcgc gccgttggtc gggttcgccg
     6901 tctccgccgc cgtcttcgtg ctcgcgctga gcctgccgaa ggcgttcgtc gaccgccccg
     6961 gcgggctgcc cggcccggtg gtcttcgccg tctgctactt cctggtccgc gcgacccagg
     7021 tgacggtctt cctctgggcc gtacgcaccg acccggcggt gcgccggcgg atgcccgtgc
     7081 tggccctgcc gttcctgatc gccacggggc tgatcctggc cgccgcgatg gtgccgcagc
     7141 gactcttcga cggcacagcc gagatcgcgc tccggctggc gttgtggctc gccgcgctcg
     7201 gtgtcgagta cggctccggc ctggtccagc agcgcgcggg ctggacggtg ctctcggcgg
     7261 ggcactgggc ggaacggcac gcgctgatca tcatggtggc gctcggtgag tcgatcatcg
     7321 cgttggggat cggacccggc accaccgccg ccctgccgct gacctggccc gtgatcatcg
     7381 cggcgttcct cggcatcgcg gtggtcgcgg cgctgtggtg ggcgtacttc gacaccctcg
     7441 ccctggccat ggagcaggtg ctgcaccgca cccgggagcg gcgcacccgc gccgggctgg
     7501 cccgggacgt gtacacgtac ctgcacctgc cgctgatcac gggcgtgatc ctgttcgccc
     7561 tgggcctcaa ggggctgatc cacgagggcg ccgacccggc gaccccgacc tggggggtgc
     7621 cgctgcccgg cttcgacatg ctggccctct tcggcggggt cgcgctctac ctgctcacgc
     7681 tggtcctgct cggcagccgg atgctgggcg cggcgcgctg gccgtcgatc ggcggggtgg
     7741 tgctgctcgc cgcgctgacc ccggtggcca cgcggctgcc ggaactggtg gccctggcca
     7801 tgctggcggt ggccgccatg ctgacggtct cggcgcagac ggtcgtcgac gcgccacggc
     7861 ggcggcgcgt gcggcaggtg gcgctggagg agcagctcgc ctccgaggcc gagcagaccc
     7921 ggtggcgggg ccaccacctc tgagggatcc gtccccggcg tccgccgccc cgcacccagc
     7981 cctgcccgac gccggtgacc ccacgccgca gcgcggggtc accggcgtcg cgtgctcaga
     8041 gctcggccag cgtgcccgcg tacaacttct cgatctcgcc ggcgaagttg ctctccacgc
     8101 cgcgacgctt gatcttgagc gacggggtga tctcgccgtc ctcgatggtc aggtcgcgcg
     8161 gcaggatggc gaccttcttg atcgtctccc agcggttgag cttggcgttg agctcggcca
     8221 cgtacccctc gaccatggcc ttcgcctccg gcgaggcgac gatctcggcg tagtcgcggc
     8281 cctccagcgg ggtgccggcg gcccagccct tgatcgcgtc cgggtccagc gtgaccagca
     8341 tcgtgcagta gttgcgggcc tggccgatca cgaccgcctg ggaggtgtac gggcaggtgg
     8401 ccttgaacat cccctcgatg tgcgagggcg cgatgtactt gccgcccgag gtcttgacca
     8461 ggtccttctt ccggtcggtg atcttgaggt agccgtcggc gtccagggtg ccgatgtcgc
     8521 cggtgcggaa gaagccgtcc tcggtgaacg cggcggcggt ctcctcgggc aggttgtggt
     8581 agccgcgcat caccggccgg ccacgcacca ggatctcgcc gtcggtgtcg atgcggcact
     8641 ccaggtcgcc catcgccttg ccgacggtgc cgatgcgcag cccgtccggc gggttgacga
     8701 agttgccggc gctggtctcg gtaaggccgt agccctcgga gatcggcagg ttcgccgcgg
     8761 cgaagaaggt ggcgatctcc gggctgagcg gggcggcgcc ggagacgagc acccggatcc
     8821 gaccgccgag gcgggcctgg agcttgctga acaccagctt ctcggccacc gtgtacttca
     8881 gcttcagccc cgtcgggacg ggcctgccgg cctgctccag ggcgaccttc tccttgccga
     8941 cccgtacgcc ccaggcgaag atcttcgcct tcgcgccgcc gccggcctgc gcggtggtca
     9001 ccgccttgtt gtagaccttc tcgaacaccc ggggcgcgcc gcacatcagc gtcggccgga
     9061 tcaccgagag caggtcgacc agcttgtcca cccgaccgtc gacgtacgtc ggcaggccca
     9121 cgtggatcgc cccgcagagc agggtcttgc cgaacgagtg cgacagcggc agccagagat
     9181 attgcaggtc gttctcgcgc agcagcccca gctcggcctg tgccacgccc tcccagcacc
     9241 agccgccgtg cagcagctcg acgcccttcg ggcgcccggt ggtgccggag gtgtagatca
     9301 gggtggccag gtggtcgggg ccgatctggg cgaccagcgt gtcgatcagg tcgggctcgg
     9361 cagccagcgc gcgggcgccc tgctcctcca actcggcgag ggtgagctgg gggacggcgg
     9421 cggccgggtc ggcggcgccg tcgaagagca cgacgtgggt cagcgccggc aggtccgcac
     9481 cggcgatctt ggcggcctgg gccgggttct cggcgaacag cacgcgggag ccggagtcgg
     9541 cgatgatgta ggtcgcgtcg tcgggctccg tggtcgggta gacggtggtg gtcgcgccgc
     9601 cggcgcacat gatgccgagg tcggcgatca cccagtcgag ccgggtgttc gccaggatcg
     9661 cgaccggatt ctccaggccg acaccgaggc cgtgcagccc ggcggcgacc gccttggcgc
     9721 gacgggccat ctgctcccag ttcagccaga ccggcccgga gtcgtcgggg gccgggtggg
     9781 cgaaggcgtc gcggtcgggg gacgccgcca cgcgcttgag gaacatgtcg gggatggaac
     9841 ggtacggtac atcgagagcc atcgctgtag ccgccttcgg gggtggagac gtgaccacgg
     9901 tcacgtcggc gttcgttacc gaagggtatt gcctgcgccc ggacatcggc tagccctgtc
     9961 gatcacggct gggccacgtc tcggaggatg gacacccggc tcaggcgtac cgggccgccc
    10021 gcagcgacca gtcgtaggtg gcgcggatcc agttgcgccg ggccgtcagg gcggaccgca
    10081 ggccggcgtc gccggtggcg agcagcgccg tctcggccgc caggtacgcc gagagggccc
    10141 cgttgaaccg gtcggccgcc gcccgcaggg ccgccgactc gtcgccgtcc gcccgccccg
    10201 cggcgatcac cgcgaccagg ttgtgcacgt cgggctgggt gaggtgctcc ttgcggtacg
    10261 agaagacgtc gttgcaccag cagaccaggt cggcggcgag caggtcgagg gcgaccagcg
    10321 acggctcggt gcggtgggcc gcgcccggca gggtgccgcc ggccagttcg gtgagggtga
    10381 agctggggtg gaccgcgccg gtgtgccggc gcatctgggc gtactcggcc agccccggca
    10441 cgcgcccgtg ctcccggttc gcggcctccc agagcagcgc cagcaggtac tcccgcacgt
    10501 ccccgacgaa gcgcagcagc gccgcgggcc cgccagccgc gtgggcccgc cggcacaggt
    10561 cggccagcgc ctcgccgagc ggcccggcca cggtggccgg cccgtcggtc gggctcccct
    10621 gcccgtcgag cacgtccagc agggcggcga cggtcggcgc cagccgggtg ggggagtcgc
    10681 cgaggccgtc ctcgtcgcag gcgtcgtcca tgacgaacag ccaggagatc aggtcggtga
    10741 gcaaccgcag cccgtcgacc gggctctcgg ggcaggcccg cccggccagc ccggcggcgt
    10801 cggcccggcg cagtcggtgc agccggtgtc cgtcaccgat cagcccatgg tcgagcgccc
    10861 actcggtgct ctcccgtgcc acccgctcgg tggcgtcgtg ctggcgctcg ggaaaggggg
    10921 gttcccgtag cgccgagacc gcaaaggtcc gcatggtgcc ccctgtcgcg ccgttcccgg
    10981 acgggacggt gcggcacagc gtacgggaac agggatcggc cgttatcgtt ggggcgtccg
    11041 gccccgcggc ctgctccgtg accgtttgcg cgcagtcggt cacatgccca ggctggcgtc
    11101 ccggagccgc tcggacagcg tcgcgggccc gtcgatctgc acccgggaca cccgctgccg
    11161 gccgctgagg aacagggcca gctcgcccgg cgcccccacc acccgcacgg gttcgccgcc
    11221 ccggccgacg gagagttcgc cgtagccggg ggcctggatg aagacgtcgg ccgggaaccg
    11281 gcgcagcgcc agccgggcca acccggcaca ccgcttccag agcgccgcgt ccagccccgc
    11341 cgacaggtcg cgcggcagcc agcccggacg ggcgcggcgg acgtcctcgt ggtggatgaa
    11401 gaactccagc gtgttggcca gctcgtcggt gaccgggttg ctcaccgggc tccacagcgg
    11461 cgggcggcgc acctcgtcga gcagccgcgg ccaggggcgc gcggcgacgc gcaggcgcac
    11521 ccgctcggcg tagccgcgta gcggcgggag caggatcccg ccggcggcgt cgggccggcg
    11581 ttcccggagc accaggtggg cggcgaggtc gcggatgtcc cacccctcgt tgaccgtcgg
    11641 cgcctccggt cccagcgtct gcatcaggtc ggcgagcgcc tcgcgctccg atcgggcgta
    11701 ccgcggcatg gcccgatcgt aggcgcgtac gacccgatcg gcgcgccgag tgggccgcgg
    11761 gccgccgtga cggcggacat agcggaccgg ggcggcggag ctggctccga ccggtaagga
    11821 tgaggaagat aattgcggct tacggcgggg gagagtgtgg cgagcaggac aagtcgggac
    11881 gtgctggttc ggggcctggt cgtcctgggg cgggcgatcc gggaggagcc ccgcatcttc
    11941 gcggtcgcgg tgagcggcag cgtcctcttc ggtgccatga cggtggccag cgccttcgtg
    12001 gtgggtgccg tggtcggcga cgtggtggtg cccgcgatcg agcgcggcgc ggtcggggtc
    12061 ggggggctcg ccctggccgc cgtcgcgctg ttcggcatca gcgtgctgcg ggtggccggc
    12121 atcttcggtc gccggctcgg cgcgggctac atgcagtacc gtctccaggc cgcctaccgg
    12181 cgccgggtga cccgccgcta cctggagctg ccgctggcct ggcaccaccg caacgccacc
    12241 ggcacgttgc tgtccaacgc caactccgac gtcgaggccg cctggtaccc gatcgctcca
    12301 ctgccgttcg cggtcggcac cctggtgatg ctggtcggcg cggtggcgtc gctcttcgtc
    12361 accgactggg cgttggcgct tgtcggtctc gcggtcttcc cggcgctctt cgcgctcaac
    12421 gtcgcctact cccggcggat ggcgccccgc caggcccggg cccagcggct gcgcgccgag
    12481 gtcagcggca tcgcgcacga gagcttcgac ggcgccctgg tcgtcaagac gatgggccgg
    12541 gaggcgcagg agaccgaccg gttcgccgcc cgcgcgggcg agctgcgcga ctcgctggtg
    12601 gcggtcgggc ggctgcgcgg cgtcttcgac ccgctgctgg agaccctgcc cagcctcggc
    12661 accctcgccg tgctggtggt cggcgcgatc cggctgcggc agggcgagat cagcgtcgcc
    12721 gagctgatca gcgtcgcctt cctcttcacg gtgctggcgt tccccgtccg ggccatcggc
    12781 tgggtgctgg ccgagctgcc gcgcagcgtc gccggctggg accgggtcag ccgggtgctc
    12841 gacgccaccg gcgagatgcc gtacggcgac accacgctcg acgtgtccga gccccgcccg
    12901 gccagcctcg cgttctccgg cgtgcgcttc ggctacgaac cggccgaggc gcacctgccc
    12961 ggcacggagg tgttgggcga ggtctccttc accgtgccgg ccgggaagat cgtcgccctg
    13021 gtcgggccga ccggctcggg caagtcgacg atcgccgcgc tggccgtacg gctggtcgac
    13081 cccctggccg gcacggtgtg cctggacggg gtcgacgtcc gccggctcac cgccgcctcg
    13141 ctgacgggca cggccgcgct ggtggcccag gtgccgttcg tcttcgacga cacggtgcgg
    13201 gccaacgtca ccctggaccg gccgggcatc ggcgacgacg acgtctgggc cgcgctgcgg
    13261 ctggccgagg cggacggttt cgtcgcggcc ctgcccgagg ggctcgacac gatggtcggc
    13321 gagcggggca cctcgctctc cggcggtcag cggcagcggc tcaccctggc ccgcgcgctc
    13381 gccggccggc cgcgcctgct ggtgctcgac gacgcgacca gtgcggtcga tccccgggtg
    13441 gaggcggcca tcctggccgg gctgcgctcg tcggcgggcg aggccggggc gccggccgcg
    13501 tcgatcctgg tggtcgccta ccggcgggcc accatcgcgc tggccgacga ggtggtctac
    13561 ctggagcagg gccgggtggt ggcccggggc ccgcacgccg agctgctggc cacggtgccg
    13621 ggctacgtcg acctggtcac cgcctacgag caggccgagg tcgaccacac caaggacgag
    13681 acgtacgacg aggtcgcccc gctgacgtcg ggcctggaaa tcgaggtgga ccggtgagtg
    13741 cgaggagtgc agcggagcgg agccccgcag tcgcgaacga aaggccagcc cggtgagtgc
    13801 gaggagtgca gcggagcgga gccccgcagt cgcgaacgaa aggccagccc ggtgagtgtt
    13861 gccactaccg cgggaacggc gcggaagccc gcgaccgacg agccgcccga gaaccccgag
    13921 acgacctggc agacgctgcg tcgtggcctg gctctctccc cggagctgcg ggtcggcctg
    13981 gccggcacgc tcggcctggc cctggtctac atggtcggcc gggcggccgt gccggtggcg
    14041 gtccagcagg gcatcgacaa cggcctcgtc ggcggcctgg acctgggcgt cgtctggacg
    14101 gtggtcgccg cgaccgccgc ggtgctggtg gtgaccacga tctgcgggta cctgatgatg
    14161 cgccggctct tcacggtcag cgagaccgcg ctggccaacg tgcggatccg ggcgttccgg
    14221 cacgtgcacg acctgtccat gctgcaccag cagtcggagc ggcgcggttc gctggtctcc
    14281 cgggtgacca gcgacgtcga ccagatcacc cagttcctcc agtggggcgg cgtgatcctg
    14341 gtgatcaacc tcggccagtt ggcggtcacc acgctggtca tgttcgcgta ctcctggcag
    14401 ttgaccctgg tggtcttcgc cgccttcctg cccgccgtgt tcctgatccg gctgctccag
    14461 cgccgcctcg cgggggcgta cggggtggtc cggcagcgta cgggggcgct gctcggcgcg
    14521 atcggggaga gcgtggtcgg cgcgccggtg atccgggcct acgggatcgc cgggcggacg
    14581 gcccgccggc tggacgaggc gatcgacggc cagcgccggg cccagcagaa ggcgatcagg
    14641 atcagcatca tgggcagctc ggtcggtgag ctggccgccg ggctggcgct ggccggcgtg
    14701 gtggtgctgg gggtgaccct cggcgccgac cgcaccctga gcatcggcga ggtgaccgcc
    14761 ttcctcttcc tggtcacgct cttcatccag ccggtgcaga tcgccaccga ggtcctcaac
    14821 gaggcgcaga atgccatcgc gggctggcgt cgggtgctgg acgtgctgga cgtcgagccc
    14881 gacgtggccg acccgggcga gcaggggcgg gacctgccgg ccggtccgct ggacatccgc
    14941 ttcgcggggg tgcgcttcgc gtaccccggc ggtccgcccg tgctgcacga cgtgagcctg
    15001 gagattccgg cgaagagccg ggtggcggtg gtgggggaga cgggcagcgg caagaccacc
    15061 ttcgccaagc tgctgacccg cctgatggac ccgaccgccg gccaggtgct gctctcgggc
    15121 gtgccgctgg agcgggtccg gttcgcctcg ctgcggtcgc gggtggtgat ggtgcctcag
    15181 gacggtttcc tcttcgacgc cacggtggcg gagaacgtcc gcttcgcccg cccggagctg
    15241 accgacgagc agctcgcggc ggccttcacc gagctggggc tggccgactg gctggacggg
    15301 cttccgtcgg gcctgcacac cccggtgggg gagcgcggcg aggcgctgag cgtgggggag
    15361 cggcagctgg tcgcgttggc ccgcgcgtac gtggccgacc cggacctgct ggtgctggac
    15421 gaggcgacca gcgcggtcga cccggccacg gaggtgcggc tgcaacgcac cctggacgcg
    15481 gtgacccggg gccgtaccac cctcgcgatc gcacaccggc tctccacggc gcaggccgca
    15541 gacgaggtga tcgtggtgga ccggggccgg atcgtccagc gcgggccgca cgacgagctg
    15601 gtccgcgacc cggagtcggt ctacggcctg ctctacgcct cctggctgga acagacccgc
    15661 tgagccgacc cgtcgcgccg gcggcgcgcg gcccggcggt gcgccgggcc gcgcggtggt
    15721 cagcgggagt agaactgcac gacgagctgc tcgtcgcaga tcaccggcac ctcgtgccgg
    15781 gcgggctcgc gcagcaacgt ggtgcgcagc tcggccagct ccaccgacag gtacggctgg
    15841 ccgggcccct cggtggcgtt ggcgcccgtg gcggcgagct ggaccggcag ggcggcgcgg
    15901 ctgcgttcgc ggacggccac cacctgtccg ggccgcagcc ggtacgacgg ccggtcgacc
    15961 ttgcgcccgt cgacggtgaa gtggccgtgg gcgaccagtt gccgggcctg gtagatgctg
    16021 cgggccaggc cggcccggtg caccaccgcg tcgagccgcc gctccaggag cgccaccagg
    16081 ccgtcgccgg tcttgcccgc gccccgggcg gcctcctcga agacgtgccg cagctgggtc
    16141 tcgctgacgt tgtactggtg gcgcaggcgc tgcttctcca gcagccgcac ctggtagtcc
    16201 gaggtcttgc ggcgttgccg gccgtgcact cccggcgggt aggggcgtcg ctcgacgtac
    16261 cgcacgcact tgcgggtcag cgggatgccg agggcgcggg agaggcgggc cttgggcctg
    16321 ggttgggtca cgctggacgt ctccgatccg gtgctctagt ctccgagtta ggtaaggcta
    16381 acctacgaag gagtcgtcca tgcggcccag cccggcggag atcgtccgca ccctcgtcgc
    16441 cggccggctg cccggcatcg cccacgtcgc gcaccggccc ggcccgcacc aggtccggca
    16501 cgtgaccgac ccggacggcc gggtgctgct gctggtgccg gtggtcagcg acctcgccgc
    16561 cgcgctgcgt cccgccggcg gcgactccga ggtcgcgctc gtgctggacg tgctggacct
    16621 gccgcccgcg gccggcgcgc cgagcctcgg ccgggcctgg gtctccggct gggcggcccg
    16681 actggacggg gacgaggagc gccgcgccgc gctggacttc gcggccgtgg agccgaccgg
    16741 tgacctgctc gacgtcggca cccggttccg gctgcaccgc ttcgaggtgg tcgaggcccg
    16801 ctgggaacgc ggcgacaccg tccgccgcat cgaccccgag gcgtacgccg aggcggaggc
    16861 cgacccgctg cacgcggtcg aggccgaact cctgaccgac ctcgccgacc accacggcac
    16921 cgaggtggcc ggctacctgt gccgtcagct cggcctcgcc gacgacgccg gcgacgccgc
    16981 gccccgggtg gtgcgcatcg accggtacgg cctgctggtc acccacggcc gacccggcgc
    17041 ccggcggcgc gtccggctgg cgttcccgcg cccgttgcag tgccaggcgg agttgacccg
    17101 gctcctgcac ccgctggtcg gccgccacgc ctcatcgccc cggcacgccg accacgcctg
    17161 accgggtgcc gccgccccgg ccgtccggtc agccggcgaa gacctcggcg aggtcgcccg
    17221 tcaggtagcg ctgcacggtg gggccgaccg ccgcgacgag cgtctccggg gcggccgagg
    17281 cgaccggttc cagccggacc acgtgccgca tcatggccag cccgatcagc tggctggcca
    17341 ccagcgagcc gcgcagcggc agctcggccg ggtcgacgtc gagctggtcg aggaccctgc
    17401 gcagcacctg ggtgaccagg aactcccgca gcagccgggc ggtccactcg ttgctcaccg
    17461 ccgagcgcag cagggccacg ccggcggtgc cggccgggga gtcccagacg ccgaggaagg
    17521 tgcgcaccag ccgctccccg agccccacgc ggtcgcccgc gagcaccctc ggcagcagct
    17581 cggccgggtc gaccggcgcg tgcatcgcgg ccaggaagag ctggtccttg ctgccgaagt
    17641 agtggtgcac cagcgccggg tccacctctg cggcggcggc gacggcccgg atcgaggccg
    17701 cgtcgaagcc ccgctcggcg aaggcggcgc gggccgcgtc gaggatggcc tgccgggtgt
    17761 ccgggttgcc gggtcgtcgt ccggtccgcc gcgccatcgt cgcccttcgc tcagccgctg
    17821 cgtcgccgga gggtggccgc ggcgagcacc agcgccagcg ccgccgcgcc ggcgaccacc
    17881 gccacgtccc gccacatcgt gccggtcggc tcggcgtggg cgccgacctc ctggagcgcc
    17941 tcgacggcgt acgacagggg cagcgcgtcg ctgaccgcct gcaaccagcc cgccatctcg
    18001 ccccggggca cgaagagccc gcagagcagc agttggggca cgaccacgac cggcatgaac
    18061 tgcacggcct ggaactcggt gcgggcgaag gcgctgcaga atagcccgag cgcgacggcg
    18121 agcacggcgt tcagcgcggc gaccaggacc accagcccgc tgttgccggc ggtgtccagc
    18181 ccgaagaccc cgtacgccac cacggtcgcg actgccgcct ggagcaccgc ggccagcccg
    18241 aacgcgatgc cgtagccgaa gagcaggtcg agcttgccca gcggggtggt gagcagccgt
    18301 tcgagggtgc ccgtggtgcg ctcgcgcagc atcgcgatgc tggtcaccag gaacatgacc
    18361 acgaagggga agaagccgag catcaccagg gcgacccggt cgaacgtcga cggctggtcg
    18421 acgtacatgg agtggaccag ggcgagcagc gccgacggga ccaccagcag cagcgccacg
    18481 gtgcgccggt cgtgccgcag ctggcgcagg atgcggccgg tggtggcggc caggatccgg
    18541 gggttcacga cgcctcccgt ccggcggcgc ccgccctgat caaccgcagg aacgcctcgt
    18601 ccaggtcgtc ggtgccggcc gcggcgcgga ccgcgtcggg ggtgtcgtcg gcgatcagcc
    18661 gcccctcgcg gatcagcagc agccggtcgc agcgggccgc ctcgtccatg acgtggctgg
    18721 agaccagcag ggtggtgccg gcggcggcca tggcgtggaa ccgggcccac aggtcggccc
    18781 gcagcaccgg gtcctgaccg acggtgggtt cgtcgaggac gagcagttcc ggttccccga
    18841 ccagggcgca ggccagcgac gcccggctgc gctgcccgcc ggagagggtg ccgaccagtt
    18901 ggccggcggc cgacccgagc ccgacctcgg cgaccgcccg gtcggcctcg gcccgccccc
    18961 ggccgtgcag ggcggcgaag tagcgcgcgt tctcccgcac cgtcaggtcg gcgtagacgc
    19021 tgggcgcctg ggtgaggtag ccgacgcggt ggcgcagctc cggcgacccg gcggggcgcc
    19081 ccagcacggt caccgagccg gcgccgacca cctgcacgcc gaccaccgcc cgcagcagcg
    19141 tggtcttgcc gctgccgctc gggccgagca gcccggtgac cacaccgcgc ggcacggacg
    19201 cgctgacacc gtgcagcacc cgccgcccgc cccgctcgac gaccaggtcg cgaacggcga
    19261 tcgcctcgtc caccggcgcc tccggggaaa ctcatcatcc gttgaactca cgctagtggg
    19321 gatgtccgcc ggagcgcaac ggtcgacttc cgggcgctcg aacggcaggt cagcgccggc
    19381 gtcggcggcg agccgggtcg gcgcgcacgc tgcaccgccc cggcgcgatc gccgaagcgc
    19441 gtaccccggg gcggcgatgc ggttggtcgg gcattagcct tcggaccgga cagcgggtcc
    19501 ggcaacgggc atccggcgcg gcagcgggca ttgcgccctg atcggacgta cggcacgatg
    19561 gcgccgtggg tcacgctgcg tcaccggacg agaggttcct cggcgaatgg gcggcccggc
    19621 tgcgggccgg tgccgagcaa cccgtggtcg gcatcatgct gcgcggcagc catgcccggc
    19681 gggccgccac cgcgcacagc gacgtcgacg tcgacgtgct gctcgccggc gccccgtacg
    19741 ccgcccgcca ggccttcctg gccgagcacg ggggccggct gacccacgtc tcggtggccg
    19801 cccgcgacgt gcgttcctgg ctggcccgcc tcggcgagcc cgccgactgg gcgttcgggc
    19861 tgccggtggc ggcgccggcc cggctgctgt gggcggatcc gcactggcgg ccccggatcg
    19921 acctgcccgt gctgtgccag cccgccggcg agccgcagct ggaggagctg atcgcgacgc
    19981 tcggtaaggt ggccggcgcg cgggacgccg acgaccacct cggtgtccgg ctggccgccg
    20041 ccgacctcgc ccggctctgc ccgtccgtgc tgcggctggc caaccccacg gtccgggtgg
    20101 cgtcccgccg gggtgccttc gccgccgccc tcgacctgcc ggtggcgccc ccgaactacc
    20161 gcgatgacct gctgctctgc ctcggcctgc ggcccggctc cgtcggtcag ctctgcgccg
    20221 ccgcggcccg cctggtcgcc ggcgtgctgc cgctgatccg cccgtacgcc gccgaggtcg
    20281 cgcgggtggc cggggcggac ctcgccgccg ccctgaccga cggccggctg gaccgctacg
    20341 tcgaccaact gacccggccc gcccacctgc ccccgcgacc ccggcgggag ccgtcgcccg
    20401 tgcccgcgcc gcgtgcggga caattggtca ctgtgcccgt acctgacgcg cccgtgaccg
    20461 gcgcccaccc cagtccgcag gagcccgcgg ccgacggcac cgcccgctcc tcccggctcg
    20521 acccggccat cgccgcccgg ctgcgccgca cccccgacgg cctggtggcc gccgtggtcc
    20581 gccagcacga ctccggcgag gtgctgatgg tcgcctggat ggacgacgag gcgctgcacc
    20641 gcaccctgac caccggccgg gccacctact ggtcgcgcag ccgccgcgag tactgggtca
    20701 agggcgccac ctccgggcac caccagtacg tccgggcggt ggcgctggac tgcgacggcg
    20761 acgcgctgct cgtcgacgtc gaccaggtcg gcgcggcctg ccacacgggg caccgcacct
    20821 gcttcttcac cgagctgccc gtcggcggcg agggggcggg ggcccggtga gcgcgtcgcg
    20881 cgcgacgccc ggcgggtccc gcaccgacgg cgcggtcagc ccggacctgg ccaccttcac
    20941 cgagctggcc gccc
//
