LOCUS       NZ_LT607733            21065 bp    DNA     circular CON 17-OCT-2024
DEFINITION  Micromonospora echinofusca strain DSM 43913 chromosome I.
ACCESSION   NZ_LT607733
VERSION     NZ_LT607733.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora echinofusca
  ORGANISM  Micromonospora echinofusca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900091445.1-RS_2024_10_17
            Annotation Date                   :: 10/17/2024 15:25:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,129
            CDSs (total)                      :: 6,059
            Genes (coding)                    :: 5,948
            CDSs (with protein)               :: 5,948
            Genes (RNA)                       :: 70
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 31 of 111
            Pseudo Genes (incomplete)         :: 94 of 111
            Pseudo Genes (internal stop)      :: 4 of 111
            Pseudo Genes (multiple problems)  :: 17 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:23:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1073515
            Orig. end                         :: 1094580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT607733.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            6..1049
                     /db_xref="GeneID:95800901"
                     /locus_tag="GA0070610_RS05020"
                     /old_locus_tag="GA0070610_1026"
     CDS             6..1049
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787380.1"
                     /locus_tag="GA0070610_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1026"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_089003278.1"
                     /transl_table=11
                     /translation="MADRRTGHPDRGSDARTERDRPGRGPVGPDEGPDSPAELPGAGWK
                     AALRRTAREFQDDSLTDWAAALTYYGVLSIFPGLLVLVSILGLLGPRATQGVKDTVNQA
                     VPQGEIRQIVEGAIDQAQQSGGFAGFAAILGLLAAFWSASGYVAAFMRASNTIYDVPEG
                     RPIWKTLPIRVGVTAVIGVMLLASAVIVVFTGGLAEQVGEAIGLGSTAVTVWNIAKWPV
                     LLLLVSLMFAILYWASPNARHGGFRWVSPGGVLAVVIWLVISGLFALYVSNFGSYNKTY
                     GALAGVIIFLIWLWLSNIAILLGAEFDAELERSRAIEAGHSPEKEPYVELRDDRKLKKK
                     RNAANRS"
     misc_feature    1457..1470
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            1581..2759
                     /db_xref="GeneID:95800902"
                     /locus_tag="GA0070610_RS05025"
                     /old_locus_tag="GA0070610_1027"
     CDS             1581..2759
                     /codon_start=1
                     /db_xref="GeneID:95800902"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287913.1"
                     /locus_tag="GA0070610_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1027"
                     /product="ROK family protein"
                     /protein_id="WP_088998939.1"
                     /transl_table=11
                     /translation="MRTVDPLHVRLLRLLRDEGAVSRAELGDRLQMPRPRLLAELERLV
                     GLGYVAEAGLAASRGGRRSTLVELSPRLRFAAVDLGASSIDVEVVNGRLEPVAAYAEAA
                     DIRTGPKVILQRVNELLHKARVDGAYERLDAVGIGVPGPVSFRDGVPVSPPIMPGWDRF
                     PVRELLTREHGCPAVVDNDVNIMAIGERHGGVAHSVDDFLFVKIGTGIGCGIYLSGEVY
                     RGTDGCAGDIGHIQVDAHGPMCSCGNVGCLEALFSGAALAKDATAAARSGASPALAERL
                     AARGAVTALDVAGGAIEGDVTCIRLIRDGGRRVGGVLAGLVSFTNPSMIVIGGGLAQLG
                     HILLAEIRSVVYRRSLPLATGNLPVVLSELGPRAGVAGAAVLASDVAFGEAS"
     gene            3056..4567
                     /db_xref="GeneID:95800903"
                     /locus_tag="GA0070610_RS05030"
                     /old_locus_tag="GA0070610_1028"
     CDS             3056..4567
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800903"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072431.1"
                     /locus_tag="GA0070610_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1028"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_172896645.1"
                     /transl_table=11
                     /translation="MVLRLTDVVKTFPGVRALDGVQLEVRAGEVHCLLGQNGAGKSTLI
                     KVLAGVHRPDSGLVEWRGSPVTFANPQAAMRAGIATIYQELDLVEDLSVAENAFLGHEP
                     RRLGFVRRGTMARRTRQILGRLGHAEIPPGRMVRALPAAGKQIVSMARALSHEARLIIM
                     DEPSAVLAHDEVGNLFRIIRELTAQGIAVIYISHRLEEIREIGDRVTVLKDGRTTAANL
                     PARDTPTRDLVSRMTGRTIEYVFPDRPAGAADGAQLLTVEGLTRAGEFADVSLDVRAGE
                     IVGIAGLVGSGRSELLETIYGARRAEAGSVRMAGRALRPGSVGAAVRSGMGMAPEERKS
                     QALLLGEPIYRNVTLATFARYARAGFTDAGRERAEADRIAESLELRPRDVRRPVRTLSG
                     GNQQKVVVGRWLLGDTRLLLLDEPTRGVDVGARAELYQVIRGLAARGVGVLLVSSEVPE
                     VLGLADRVLVMREGRVVHEAPARELDENTVLDLVMAGSLMEGAPA"
     gene            4564..5688
                     /db_xref="GeneID:95800904"
                     /locus_tag="GA0070610_RS05035"
                     /old_locus_tag="GA0070610_1029"
     CDS             4564..5688
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800904"
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072430.1"
                     /locus_tag="GA0070610_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1029"
                     /product="ABC transporter permease"
                     /protein_id="WP_088998940.1"
                     /transl_table=11
                     /translation="MTEGPTPTVAPQPAAHLPAQSPPVHPAQTGAAGDKVAAPGRISWW
                     RGDGGEGARRNLGLIGVLVVLVVIGALTRSDLYSNPDWVWDNVLSILKLAAVVGVVTVG
                     MTFVIIGGGIDLSVGAIVALAGVWCTTVATQSYGAGGMVFSALTVGLAVGLVNGLLISY
                     GRLVPFIATLAMLVAARGLAAEISDKQTQVSENGFINGLASNSLLGIPLLVYILAAVVA
                     AGWVLLNRTTFGRRTVAVGGNPEAARLAGINVRRHTVLLYALSGLCCGIAAIMLTAQAN
                     SAQAAMANLYELDAIAAAIIGGTLLSGGRGTIIGSLLGVVIFATITNLFAINGLSTEAQ
                     NMVKGGIIVAAVLVQQVQFRSLTQFLGRNRLTTT"
     gene            5854..6909
                     /db_xref="GeneID:95800905"
                     /locus_tag="GA0070610_RS05040"
                     /old_locus_tag="GA0070610_1030"
     CDS             5854..6909
                     /codon_start=1
                     /db_xref="GeneID:95800905"
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783811.1"
                     /locus_tag="GA0070610_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1030"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_088998941.1"
                     /transl_table=11
                     /translation="MTQHSRDMSRRRLLFGGAAVGAGVLLAGCTSNETKPTEAQTKAAA
                     APGGNNEPGKRVVIGFSAPAADHGWIAAITNNAKAQAGTYSDVEFKSVEAGADAAAQRA
                     ALSTLISQKPDVIVLLPHDGKELNAFGLEAMKAGVPVVNLDRAFPDARAYRLQIKGDNY
                     GMGVAAATYMIEQFKAKGVSNPVIAEIAGMDELELTQERSKGFLDTLTASGFKVANRRA
                     ARFTADSGQQEAAQLLQALPKIDALWNHDDDQGIGVLAAVNQSGRKEFFMVGGAGSKKA
                     MEDIQADNTVLKATVTYSPSMASSAISLARLIGQGRGMSDLVELQVPKEIILASETITK
                     ENAGDYLKLGF"
     gene            6963..8186
                     /db_xref="GeneID:95800906"
                     /locus_tag="GA0070610_RS05045"
                     /old_locus_tag="GA0070610_1031"
     CDS             6963..8186
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800906"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020521533.1"
                     /locus_tag="GA0070610_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1031"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_172896646.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.3e-23, bitscore:
                     81.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-28,
                     bitscore: 97.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGYAFMGAAHSQAWRTVNRVFDLPARARMALICGRDTAKVADAA
                     GRLGWDAHTTDWRELVASDDIDVVDVCTPGDSHAEIALAALAAGKHVLCEKPLANTISE
                     ARAMAAAAVTAQAAGVRSMCGFNYRRVPAVAMMRQLVADGRLGVIRHVRATYLQDWIVD
                     PQFPLVWRLQRDRAGSGALGDIGAHIIDLTQYVTGRRITGVSAVTETFVKERPLPAGSS
                     GLAATVDGAAVDGLTAADANGADGHRPATGMVTVDDAAVFVARLDGGVLATYEASRFAT
                     GRKNALRVEINGSLGTVAFDLERLNELEFYDATRPAAEQGFSRILVTEGEHPYMSAWWP
                     PGHIIGYEHSFTHQARDFIEAVATGVDPAPSFVDGLQVQLVLDAVTRSAELGSSWTEVE
                     PALTTVAA"
     misc_feature    8454..8468
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     misc_feature    8598..8611
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.14"
                     /tool="antismash"
     misc_feature    complement(8598..8612)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.67"
                     /tool="antismash"
     misc_feature    complement(8599..8612)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.72"
                     /tool="antismash"
     misc_feature    complement(8601..8614)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.78"
                     /tool="antismash"
     gene            8672..9832
                     /db_xref="GeneID:95800907"
                     /locus_tag="GA0070610_RS05050"
                     /old_locus_tag="GA0070610_1032"
     CDS             8672..9832
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783813.1"
                     /locus_tag="GA0070610_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1032"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_088998943.1"
                     /transl_table=11
                     /translation="MRTGVWLVGARGSVATTSIVGALALRSGLTGPTGCVTELPDLRGP
                     ALPAFTDLVFGGHDVATTPLAKRAEALAAAGVLPGRLVAALPDELAAVERALRPAPAGG
                     TQTDRAAATVRDLTDFRRRHRLDRVVVVNVSATEPAARPHPGHADPGALAAALADGDEV
                     LPPSSLYAYAAVRAGCPYVDFTPSTGLRLPALTALAAEYGVPYAGHDGKTGETLVKSVL
                     APMFAMRHLAVRSWSGVNLLGGGDGATLADPAANAAKVESKQRVLGETLGHLPQGGTRI
                     EYVEALGDFKTAWDLVTFAGFLGTGMRMEFTWHGCDSALAAPLVLDLARLTAAAHAAGH
                     AGPLVDLAFFFKDPLGAPTHSLAEQWTRLCDLARRLHAGDTDATPR"
     gene            9816..10004
                     /db_xref="GeneID:95800908"
                     /locus_tag="GA0070610_RS05055"
                     /old_locus_tag="GA0070610_1033"
     CDS             9816..10004
                     /codon_start=1
                     /db_xref="GeneID:95800908"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GA0070610_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GA0070610_1033"
                     /product="hypothetical protein"
                     /protein_id="WP_231925912.1"
                     /transl_table=11
                     /translation="MPRLADLAELVRAPAALSVPGDVVAGAAAAGTLGRRTPALAAASV
                     LLYWAGMASPPAPGEGP"
     gene            10001..11065
                     /db_xref="GeneID:95800909"
                     /locus_tag="GA0070610_RS05060"
                     /old_locus_tag="GA0070610_1034"
     CDS             10001..11065
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800909"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018349756.1"
                     /locus_tag="GA0070610_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1034"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_172896401.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-39, bitscore:
                     134.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADAATDTSGLRARFDAALAAFLDRQGRDWPDGAPRGVFTALHR
                     FVLAGGKRLRPLFCYWGWRGADGVDGAPIVTAAAALELFHAFALIHDDILDGSDRRRGG
                     PSVHRLFADLHARSSWRGDPEAYGRNTALLCGDLCAAWSDQMFHECGLDPGRVHRGYAV
                     YALMRTEVIAGEYLDLVSGVGDGSVASALTVVRMKAARYTVTRPLQIGATLAGAGPERV
                     AALAGFGDPLGDAFQLRDDVLGVFGDPAVTGKSVLDDLREGKPTVMMALARGAADRVQA
                     ARLRELFGNPALDGDGAAELRKIIEATGARERIEGMIRVRAEAALAALASAPVTAEARA
                     ALAGLAAQAVDRPC"
     gene            11373..14240
                     /db_xref="GeneID:95800910"
                     /locus_tag="GA0070610_RS05065"
                     /old_locus_tag="GA0070610_1035"
     CDS             11373..14240
                     /codon_start=1
                     /db_xref="GeneID:95800910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463796.1"
                     /locus_tag="GA0070610_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1035"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_088998945.1"
                     /transl_table=11
                     /translation="MSTQDAPIHRLRRRLSAASALLLAATAGTVALGAGPATLGGPTPA
                     EAHPVVGTDFQQVTLAKGVAEVGEPMTIAVLPDRSVLHTARNGTVRRTDSAGTTSVIGT
                     VPVYTHDEEGLQGIGADPNFATNRHIYLYYAPPLATPAGDAPATGSDFSAWQGVNRLSR
                     FTLNADFTMNTGSKVDILDVPADRGMCCHVGGDIDFDAAGNLYLSTGDDTNPFDSAGYA
                     PIDERTNRNPAYDAQRSAANTNDLRGKILRIKVNANGTYSIPAGNMFVDSDARTRPEIY
                     AMGFRNPFRMSVDRATGIVYVGDYGPDAGTTSARGPSGQVEFNRITGPGNYGWPYCTGT
                     NTATETYAEWDFAAGTAGAKYNCSGGPTNNSFRNTGLPTLPGAKPAWIRYAGDAGTPPE
                     FGGGSESPMGGPVYRYDAALNSTTKFPQSFDGQFFAGELGRGWVKPIHLNADGSPGTID
                     TFPWNGKQIMDMAFGPEGALYILDYGTGYFNGDANSALYRYDYIAGGNRAPTAVAAADK
                     TSGAAPLTVNFSSAGSSDPEGGTLTYSWAFGDGTSSTAANPSKTYTANGTYQVTLTVRD
                     PQGATGTANVQIGVGNTAPTVTIDSPANGKLFSYGDTVPFSITVTDPEDAAIDCTKVKM
                     TYVLGHDNHGHQITSKNGCSGSITIPVDGEHDDAANIFAVFDAEYTDAGGLTTHKQHTL
                     QPRKRQAEHFKTSSGVGTFDKATAEGGKTVGDIHNGDWIAFEPYRIDNATSFSARVSSA
                     GAGGTLQVRVGSPTGTVLGSATVPVTGAWDTFTTVSGSISGAPASTGTLYLTFAGAGTG
                     ALYDVDTFAFTTGAAGVRTGPVVGLGGKCLDVRNAATADGTQIQIYGCNGTAAQTWTVT
                     PNSTVKALGKCLDISGGGSADGTKIQLYGCNGTGAQNWSAQADGTLKNPQSGKCLDVSG
                     NNPADGQAVHLWTCHTGANQKWTLP"
     gene            14316..16424
                     /db_xref="GeneID:95800911"
                     /locus_tag="GA0070610_RS05070"
                     /old_locus_tag="GA0070610_1036"
     CDS             14316..16424
                     /codon_start=1
                     /db_xref="GeneID:95800911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735334.1"
                     /locus_tag="GA0070610_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1036"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_088998946.1"
                     /transl_table=11
                     /translation="MRRLLRPLLGAATAVLAVLACTTPATPASAADAPYDVLVFSKTAG
                     FRHDSIAVGTQAIRDLGAANNFTVTATEDAAQFTTANLSRFEAVVFLNTTGDVLDATQQ
                     SAFESYIGAGGGYVGVHAAADTEYGWSFYGNLVGAYFASHPHIQQANVKAENRAHAATA
                     HLPQTWTRTDEWYNYQTNARSTARVLATLDESSYSGGSMGADHPHSWCKTHSGGRSFYT
                     GGGHTQASYAEPAFRAHLLGGIRYAAGRAKADCRPESGYTPLYNGSTTGWSQAGPGSFS
                     NADATLTSVGGMGLYWYSAKQFTNYSLKLDWRLAGDDNSGVFIGFPASSDPWSAVNNGY
                     EVQIDATDAADRTTGAVYTFKSADIAARDAALNPPGEWNTYELLVEGERLQVFLNGVKI
                     NDFTNTDPVRSLAGHIGLQNHGTGDDASFRNIRIRELGVDPPGGNTTVQAEAFSSAGGV
                     APFAKAGANGGQTLGHIDPGDWAAYAGVDLTGVTSLRARVVSGGPGGTLQVRTGSTTGT
                     VLGSVAVPNTGSWTTFADVTTALSGVPSGTRDLYLTFTGSGTGLFDVDDFTLVRSGGSG
                     GVGPIRGLGGKCLDVRNAATADGTQIQIHGCNGTAAQTWTVTPNSTVKALGKCLDVSGG
                     ASADGTKIQLWTCNGTGAQNWSAQADGTLKNPQTGKCLDVSGNNPADGQAVHLWTCHTG
                     ANQKWTLP"
     gene            16730..17737
                     /db_xref="GeneID:95800912"
                     /locus_tag="GA0070610_RS05075"
                     /old_locus_tag="GA0070610_1037"
     CDS             16730..17737
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463784.1"
                     /locus_tag="GA0070610_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1037"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_088998947.1"
                     /transl_table=11
                     /translation="MARPITLFTGQWADLPFDEVCRLAAEWGYDGLEIACWGDHFEVDK
                     ALADDSYVERKRETLAKHNLKVFAISNHLVGQAVCDHPIDERHQGILPARIWGDGEPEG
                     VRRRAAEEVKDTARAAAKLGVDTVVGFTGSSIWHTLAMFPPVPPSMIERGYQDFADRWN
                     PILDVFDETGVRFAHEVHPSEIAYDYWTTKRTLEAVGHRPAFGLNWDPSHFVWQELDPV
                     NFIFDFADRIYHVDCKDAKVRTGDGRRGRLASHLPWADMRRGWDFVSTGHGDVPWEDCF
                     RALNAIGYAGPISIEWEDAGMDRLVGAPEALQFVRRLAFDAPAAAFDAAFSSKD"
     gene            complement(17919..18323)
                     /db_xref="GeneID:95800913"
                     /locus_tag="GA0070610_RS05080"
                     /old_locus_tag="GA0070610_1038"
     CDS             complement(17919..18323)
                     /codon_start=1
                     /db_xref="GeneID:95800913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463781.1"
                     /locus_tag="GA0070610_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1038"
                     /product="hypothetical protein"
                     /protein_id="WP_088998948.1"
                     /transl_table=11
                     /translation="MRGKMMFLGGLAAGFVLGARAGREKYEELVIRGRKVLDHPTVQEA
                     AGVAQAQATRLYSEGKDKLGQSKLGEKLSTNGQKQELTAADDAFAGTPATVGAKSASGS
                     SSTSATPGSTSATTTPRSKPSSSGTNGSTL"
     misc_feature    18445..18465
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     tRNA            18596..18668
                     /anticodon=(pos:1092144..1092146,aa:Asn,seq:gtt)
                     /db_xref="GeneID:95800914"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GA0070610_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GA0070610_1039"
                     /product="tRNA-Asn"
     gene            18596..18668
                     /db_xref="GeneID:95800914"
                     /locus_tag="GA0070610_RS05085"
                     /old_locus_tag="GA0070610_1039"
     misc_feature    18646..18659
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            18849..20971
                     /db_xref="GeneID:95800915"
                     /locus_tag="GA0070610_RS05090"
                     /old_locus_tag="GA0070610_1040"
                     /pseudo=""
     CDS             18849..20971
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:95800915"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018738973.1"
                     /locus_tag="GA0070610_RS05090"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GA0070610_1040"
                     /product="MMPL family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPGRGGHGRITLVAVAVVLAWLVVGAVAGPYAGRLSEVATNDNAS
                     FLPAEAEATRAQELSARFVERPTTPALVVYERAGGLTDADAQRVAADAARFARVPGVVG
                     PLPPPIPSEDGQALQVVVPIDDADGERIGTVVEELRAIAGDDRDGLGVDVAGPAGLLAD
                     LIEVFSAIDGTLLIVTLCVVLVILLVVYRSPVLWIFPLLSAGMSFALAAVFVHLLADAD
                     VIKLNGQAQGILTVLVFGAGTDYALLLVARYREELHRHERPWDAMRAAWRGAAPAIVAS
                     GGTVIVSLLCLLLSSLNSNRALGPVAAIGIGATLLVMLTFLPALLVLGGRWAFWPRRPP
                     RTTGPTPGPSTASGAGSPASSPGGRDPSGCSPPSPWPRSHSA"
ORIGIN
        1 gccggatggc cgaccgccgg acgggccacc ccgaccgggg gtccgacgcg cgtaccgagc
       61 gagaccgccc ggggcgcggc ccggtcgggc ccgacgaggg tcccgacagc ccggccgagc
      121 tgccgggcgc cgggtggaag gccgcgctgc gtcgcaccgc acgggagttc caggacgaca
      181 gtctgaccga ctgggcggcg gccctgacgt actacggcgt actctccatc ttccccggcc
      241 tgttggtgct ggtgtcgatc ctcggcctgc tcggtccgcg ggcgacgcag ggcgtcaagg
      301 acaccgtcaa ccaggcggtc ccgcagggcg agatccggca gatcgtcgag ggggcgatcg
      361 accaggcgca gcagagcggc ggtttcgccg gtttcgccgc gatcctgggt ctgctggccg
      421 ccttctggtc ggcgtcgggt tacgtcgccg cgttcatgcg cgcctccaac accatctacg
      481 acgtgccgga ggggcgcccg atctggaaga ccctgccgat ccgcgtcggg gtgaccgcgg
      541 tgatcggtgt gatgctgctg gccagcgccg tgatcgtggt cttcaccggc ggcctcgccg
      601 agcaggtggg ggaggcgatc gggctgggct cgacggcggt gaccgtgtgg aacatcgcca
      661 agtggccggt gctgctgctc ctggtgagcc tgatgttcgc gatcctctac tgggcgtcgc
      721 cgaacgcgcg acacggtggc ttccgctggg tcagccccgg tggcgtactg gccgtggtga
      781 tctggctggt gatctcgggc ctgttcgcgc tctacgtcag caacttcggc tcgtacaaca
      841 agacgtacgg ggcgctcgcc ggtgtgatca tcttcctgat ctggctgtgg ctgagcaaca
      901 tcgcgatcct gctcggcgcg gagttcgacg ccgagttgga gcgcagccgc gccatcgagg
      961 cgggccactc gccggagaag gagccgtacg tcgagctgcg cgacgaccgc aagctcaaga
     1021 agaagcgcaa cgccgccaac cgcagctgac cctccgcccg caaccgcaac tgcacccgtc
     1081 ttcccgccgc cccgccacca gtccggtgcc ggggcggtgg cacgtcccgc gccggcgcgc
     1141 acgtgtccgc ccgcccgcct cttgggcgca cgtgtccgcc cgcccgcctc ttggacgcgc
     1201 ccgcctcttg gacgcgcccg cctcttggcg cgtgccgcct gcctccgcag gggtgagcgc
     1261 cccggtgatc aggacgtggt ggacgtcatc cgccggcttt gaggtacatg gcgtcctgat
     1321 caccggcggc tgggaacgcg gtagcgcagc ggctgggctg cggcagcacc ctcggccggg
     1381 tctcggcgtt cgtggatcgc ctcgtggtgc gcggtggggg ccgcttttct tgatccaccc
     1441 gaagcttttg ctcgtaggga caaaagttcg cgccaaatcg gccgaagctc tggacacgtg
     1501 acacggaaca ctcctactgt gtcgggcacg acacctcggc agtacgtcga tgtgcacgag
     1561 cccgcgaaga ggtgagtccg gtgcggacgg tcgaccccct gcacgtacgg ctgctgcgcc
     1621 tgctccgtga cgagggtgcg gtgtcccggg ccgagctggg cgaccggctt cagatgcccc
     1681 gtccccggtt gctggcggag ctggaacggc tcgtcggcct cggctacgtg gccgaggcgg
     1741 ggctggctgc ctcccggggc ggccgccgct ccaccctcgt cgagctgagc ccgcgcctgc
     1801 gcttcgccgc cgtcgacctc ggcgccagct ccatcgacgt cgaggtggtc aacggtcggc
     1861 tggagccggt cgccgcgtac gccgaggcgg ccgacatccg caccggcccg aaggtgatcc
     1921 tccagcgggt caacgagctg ctgcacaagg cccgggtgga cggcgcctac gagcggctcg
     1981 acgccgtcgg catcggcgtg cccggcccgg tcagcttccg cgacggcgtg ccggtctccc
     2041 cgccgatcat gccggggtgg gaccggttcc cggtgcgcga gctgctcacc cgtgagcacg
     2101 gctgcccggc ggtcgtcgac aacgacgtca acatcatggc gatcggggag cggcacggcg
     2161 gggtcgcgca ctccgtggac gacttcctct tcgtgaagat cggcaccgga atagggtgcg
     2221 ggatctacct cagcggcgag gtctaccggg gcaccgacgg ctgtgccggc gacatcggcc
     2281 acatccaggt cgacgcgcac ggcccgatgt gctcctgcgg caacgtcggc tgcctcgaag
     2341 cgctgttcag cggggccgcg ctggccaagg acgcgaccgc cgccgcgcgc agcggcgcct
     2401 cgcccgcgct ggccgaacgg ctggccgcgc gcggcgcggt gaccgccctg gacgtcgccg
     2461 ggggtgcgat cgagggggac gtgacctgca tccggctgat ccgcgacggg ggtcggcggg
     2521 tcggtggggt cctggccggg ctggtcagct tcaccaaccc gtcgatgatc gtgatcggtg
     2581 gcgggctcgc ccagctcggg cacatcctcc tcgccgagat ccgcagcgtg gtctaccgcc
     2641 ggtcgctgcc gctggccacc ggcaacctgc ccgtcgtgct gtccgaactc ggcccacgcg
     2701 ccggcgtggc cggcgcggcc gtgctcgcca gcgacgtcgc cttcggggag gcatcgtgag
     2761 cgcgaggagt gagccgggtc tgcgagcccc gcagtcgcga acgaaggtgg cgctgtgagc
     2821 gcgaggagtg agccgggtct gcgagccccg cagtcgcgaa cgaaggtggc gctgtgagcg
     2881 cgaggagtga gccgggtctg cgagccccgc agtcgcgacc ggagaaggtg tcgtgaccga
     2941 gcgcgaggag gagaccgtgg cccgaaccga ggagacgccc gccgccgggc cggcgccgct
     3001 cgcccccgcc gacgccccgc tggtcgaggc gcccgccgac gccgtcgcgg gcgaggtggt
     3061 gctgcgcctc accgacgtgg tcaagacctt cccgggcgta cgcgccctgg acggggtgca
     3121 gctggaggtg cgcgccggcg aggtgcactg cctgctcggt cagaacggcg ccggcaagtc
     3181 caccctgatc aaggtgctgg ccggggtgca ccggcccgac tcggggctcg tcgaatggcg
     3241 gggcagcccg gtcaccttcg ccaacccgca ggccgccatg cgcgccggca tcgccacgat
     3301 ctaccaggaa ctcgacctgg tcgaggacct ctcggtggcg gagaacgcct tcctcggcca
     3361 cgagccgcgc cggctcggct tcgtccggcg gggcaccatg gcccggcgta cccggcagat
     3421 cctcggtcgg ctcggccacg ccgagatccc gcccgggcgg atggtgcgcg cgctgcccgc
     3481 cgccggcaag cagatcgtca gcatggcccg cgcgctctcc cacgaggccc ggctgatcat
     3541 catggacgag ccgagcgccg tgctggccca cgacgaggtg ggcaacctgt tccggatcat
     3601 ccgggagctg accgcgcagg gcatcgccgt catctacatc tcgcaccggc tggaggagat
     3661 ccgcgagatc ggcgaccggg tcaccgtact caaggacggc cggaccaccg cggcgaacct
     3721 gccggcccgc gacaccccga cccgcgacct ggtcagccgg atgacgggcc gcaccatcga
     3781 gtacgtcttc ccggaccgcc cggccggcgc ggccgacggc gcgcagctgc tcacggtcga
     3841 agggctgacc cgggccggcg agttcgccga cgtctcgctc gacgtccggg ccggcgagat
     3901 cgtcggcatc gccgggctgg tcggctcggg ccgttccgag ctgctggaga ccatctacgg
     3961 cgcgcgccgc gccgaggccg gctcggtgcg gatggccggc cgggcgctgc gccccggcag
     4021 cgtcggcgcg gcggtgcgct ccggcatggg gatggccccc gaggaacgca agagccaggc
     4081 gctgctgctg ggcgagccga tctaccgcaa cgtgaccctg gcgaccttcg cccgctacgc
     4141 ccgcgccggg ttcaccgacg cggggcggga acgggcggag gcggaccgga tcgccgagag
     4201 cctggagctg cgcccccgcg acgtacgccg gccggtgcgc accctctcgg gcggcaacca
     4261 gcagaaggtg gtggtcggcc gctggctgct cggcgacacc cggctgctgc tgctcgacga
     4321 gccgacccgg ggcgtcgacg tcggcgcgcg ggcggagctc taccaggtga tccgggggct
     4381 ggccgcgcgc ggcgtcgggg tgctgctggt ctccagcgag gtccccgagg tgctcggcct
     4441 ggccgaccgg gtgctggtga tgcgggaggg gcgggtcgtc cacgaggccc cggcccgcga
     4501 actcgatgag aacaccgtgc tcgacctcgt catggcgggg tccctgatgg aaggcgcgcc
     4561 ggcatgaccg agggtcctac tcccaccgtg gcgccgcagc cggcggcaca cctgccggcg
     4621 cagtcgccgc cggtgcatcc cgcacagacc ggggcggccg gcgacaaggt ggcggcaccg
     4681 ggccggatct cctggtggcg gggcgacggc ggcgagggcg cccgccgcaa cctcggcctg
     4741 atcggggtgc tggtcgtgct cgtcgtgatc ggcgccctca cccgctccga cctgtactcg
     4801 aacccggact gggtgtggga caacgtcctg agcatcctca agctggcggc cgtggtcggc
     4861 gtggtcaccg tgggcatgac cttcgtgatc atcggcgggg gcatcgacct ctccgtcggc
     4921 gcgatcgtcg cgctggccgg cgtctggtgc accacggtgg ccacccagag ctacggcgcc
     4981 ggcggcatgg tcttcagcgc gctcaccgtc gggctggcgg tcggcctggt caacgggctg
     5041 ctcatctcgt acggccggct ggtgccgttc atcgccacgc tcgccatgct ggtggccgcc
     5101 cggggcctgg ccgccgagat ctccgacaag cagacccagg tgtcggagaa cggcttcatc
     5161 aacgggctcg ccagcaacag cctgctcggc atcccgctgc tggtctacat cctcgccgcc
     5221 gtggtggccg ccggctgggt gctgctcaac cgcaccacct tcggccggcg tacggtcgcc
     5281 gtcggcggca acccggaggc cgcccggctc gccggcatca acgtccggcg gcacaccgtg
     5341 ctgctctacg cgctctccgg cctctgctgc gggatcgccg ccatcatgct caccgcccag
     5401 gccaactcgg cgcaggcggc gatggcgaac ctctacgagc tggacgcgat cgccgccgcg
     5461 atcatcggcg gcacgctgct cagcggcggg cggggcacca tcatcggctc cctgctcggg
     5521 gtggtcatct tcgccaccat caccaacctc ttcgccatca acggcctctc caccgaggcc
     5581 cagaacatgg tcaagggcgg catcatcgtc gccgccgtcc tggtccagca ggtccagttc
     5641 cgcagcctca cccagttcct gggccgcaac cggctcacca ccacctgacc cgcaccacag
     5701 cacaccgggc cgcgtcgcac cgacccgtac ccgaaccgca tccgcactcc gcgcgacatc
     5761 cgggccaccc gaacgacggt ggccgggccc cgtacgccct cttccgtccc gcaccgcgag
     5821 tttcctccac caccgtcaac ccaggaggtc gtcatgaccc agcacagtcg cgacatgtca
     5881 cgccgccgac tgctcttcgg cggggccgcc gtcggcgccg gcgtgctgct cgccggctgc
     5941 accagcaacg agaccaagcc gaccgaggcg cagaccaagg cggcggccgc gccgggcggc
     6001 aacaacgagc ccggcaagcg ggtcgtcatc ggcttctccg cgccggctgc ggaccacggc
     6061 tggatcgccg ccatcaccaa caacgccaag gcccaggccg ggacgtactc cgacgtggag
     6121 ttcaagtcgg tcgaggccgg cgcggacgcg gcggcccagc gggcggcgct gtccacgctg
     6181 atctcgcaga agccggacgt gatcgtgctg ctgccgcacg acggcaagga gctcaacgcg
     6241 ttcggcctgg aggcgatgaa ggccggcgtg ccggtggtca acctggaccg ggcgttcccc
     6301 gacgcgcggg cctaccggct ccagatcaag ggcgacaact acggcatggg ggtggccgcc
     6361 gccacctaca tgatcgagca gttcaaggcc aagggcgtca gcaaccccgt gatcgccgag
     6421 atcgccggca tggacgagct ggagctgacc caggagcggt cgaagggctt cctcgacacc
     6481 ctgacggcga gcggcttcaa ggtcgccaac cggcgggccg cccggttcac ggccgactcg
     6541 gggcagcagg aggcggcgca gctgctccag gccctgccga agatcgacgc actctggaac
     6601 cacgacgacg accagggcat cggcgtgctg gcggcggtca accagagcgg ccgcaaggag
     6661 ttcttcatgg tcggtggcgc cggctcgaag aaggcgatgg aggacatcca ggcggacaac
     6721 acggtgctca aggcgaccgt gacctacagc ccctcgatgg cctcctcggc catctccctg
     6781 gcccgcctga tcggccaggg caggggcatg tccgacctgg tggaactcca ggtgcccaag
     6841 gagatcatcc tcgcctcgga gacgatcacc aaggagaacg cgggcgacta cctcaagctc
     6901 gggttctgac acacgggggg agacccacct tgtccacgac agacagagaa ctgcgggtcg
     6961 gcatggtcgg ctacgcgttc atgggcgccg cgcactcgca ggcgtggcgc accgtgaacc
     7021 gggtgttcga cctgccggcg cgggcccgga tggcgttgat ctgcggccgg gacaccgcga
     7081 aggtggccga cgccgccggc cggctcggct gggacgcgca cacgaccgac tggcgcgagc
     7141 tggtcgcctc cgacgacatc gacgtggtcg acgtctgcac gccgggggac agccacgccg
     7201 agatcgccct cgccgcgctg gccgccggca agcacgtgct gtgcgagaag ccgctggcca
     7261 acacgatctc ggaggcccgg gcgatggccg ccgcggcggt caccgcgcag gccgccgggg
     7321 tgcggtcgat gtgcgggttc aactaccggc gggtgccggc ggtcgcgatg atgcgccagc
     7381 tcgtcgccga cggtcggctc ggggtgatcc ggcacgtccg ggcgacgtac ctgcaggact
     7441 ggatcgtgga cccgcagttc cccctggtct ggcggttgca gcgggaccgg gccggctccg
     7501 gtgcgctcgg cgacatcggc gcgcacatca tcgacctgac ccagtacgtc accggccggc
     7561 ggatcaccgg ggtcagcgcg gtcaccgaga cgttcgtcaa ggagcggccg ctgccggccg
     7621 ggtcgagcgg gctggcggcg acggtggacg gggcagcggt ggacgggctg acggcggccg
     7681 acgcgaacgg cgccgacggt caccgcccgg ccaccgggat ggtgaccgtc gacgacgcgg
     7741 cggtcttcgt ggcccggctc gacggcggcg tgctggccac gtacgaggcg agccgcttcg
     7801 ccacgggacg caagaacgcc ctccgggtgg agatcaacgg ctcgctgggc acggtggcct
     7861 tcgacctgga acgcctcaac gagctggagt tctacgacgc gacgcgcccg gccgccgagc
     7921 agggcttcag ccgcatcctg gtgaccgagg gggagcaccc gtacatgtcc gcgtggtggc
     7981 cgcccgggca catcatcggc tacgagcact ccttcaccca ccaggcgcgg gacttcatcg
     8041 aggcggtcgc caccggcgtc gacccggccc cctccttcgt ggacgggttg caggtccagc
     8101 tcgtgctgga cgcggtgacc cggtcggcgg agctgggctc ctcgtggacg gaggtggagc
     8161 cggccctgac cacggtggcc gcctgagccg actccggtgc cgaccggcga gggtccggcc
     8221 gcggttgcgc cccgcggccg ggacgaggtc ggaaccggag ggcgtgcggc cgggccggcg
     8281 tggcccggtg ccgcacgagc agaacggtcg tccggtgcgg ccggaccggg attccccggc
     8341 cgcaccggag gaccgtcacc acccggcgac gccgccgggc cgtgtcaccc cacgacgtcc
     8401 ggtcggcgcg cgccgtcgtc ccggccggcg gacgcggggg aggcagggac gggacgccga
     8461 ccggccctgc ctgccagccc cgtccgtccg cgcccgcacc gggagccggg ccggggtcgt
     8521 cgccgccgac gtcgacaccg gaccggcggg ctccacccgg ggcagccggc ggacggggcc
     8581 catccgcata gatccgtatc tttctgaaca aacttctgat atctatgtaa ctcaatgcac
     8641 ggctggttcc tcctgatcgg gaaggagcac catgcgtacg ggtgtctggc tggtgggagc
     8701 gcgcggctcg gtcgcgacca ccagcatcgt gggggcgctc gccctgcggt ccgggctcac
     8761 cggcccgacc ggctgcgtca ccgagctgcc cgacctgcgt gggcccgccc tgccggcctt
     8821 caccgacctg gtcttcggcg ggcacgacgt tgccaccacc ccgctggcga agcgggccga
     8881 ggccctggcc gccgccggcg tgctgcccgg ccggctggtc gccgccctcc ccgacgaact
     8941 ggccgcggtc gaacgcgcgc tgcgcccggc ccccgccggc ggcacccaga cggaccgggc
     9001 cgccgcgacc gtacgcgacc tgaccgactt ccgccgccgg caccggctcg accgggtcgt
     9061 ggtggtcaac gtctcggcca ccgaaccggc cgcccgaccg cacccgggcc acgccgaccc
     9121 gggcgcgctg gccgccgcgc tcgccgatgg cgacgaggtg ctgccgccca gctccctcta
     9181 cgcgtacgcg gcggtgcgcg ccggctgccc gtacgtcgac ttcaccccgt ccaccgggct
     9241 gcggctgccg gccctgacgg cgctggccgc cgagtacggc gtcccgtacg ccgggcacga
     9301 cggcaagacg ggggagaccc tggtcaagtc cgtgctcgcg ccgatgttcg cgatgcggca
     9361 cctcgcggtg cgttcctggt ccggggtcaa cctgctcggc ggtggcgacg gcgccaccct
     9421 cgccgacccg gcggccaacg cggccaaggt ggagagcaag cagcgggtgc tcggcgagac
     9481 cctcggccac ctgccgcagg gcggcacccg gatcgagtac gtcgaggcgc tgggcgactt
     9541 caagaccgcg tgggacctgg tcaccttcgc cggcttcctc ggcaccggga tgcggatgga
     9601 gttcacctgg cacggctgcg actccgcgct ggccgcgccc ctcgtgctcg acctggcccg
     9661 gctcaccgcc gccgcgcacg ccgccggcca cgccggcccg ctggtggacc tcgccttctt
     9721 cttcaaggac ccgctcggcg cgcccaccca ctcgctggcc gagcagtgga cccggctgtg
     9781 cgacctcgcc cgccggctgc acgcggggga caccgatgcc acgcctcgct gacctcgccg
     9841 aactcgtccg ggcaccggcc gcgctgtcgg tacccgggga cgtcgtggcc ggcgcggcgg
     9901 ccgccggcac gctcggccgg cgtacgcccg cgctggccgc cgcgtccgtc ctgctctact
     9961 gggcggggat ggcgtccccg cctgcccccg gggagggacc gtgaccgccg acgccgcgac
    10021 cgacacgagc ggcctgcggg cgcgcttcga cgccgcgctc gccgcgttcc tcgaccggca
    10081 gggccgggac tggccggacg gcgcaccccg gggcgtcttc accgcgctgc accggttcgt
    10141 gctggccggc ggcaagcggc tgcgcccgct cttctgctac tggggctggc ggggcgcgga
    10201 cggcgtcgac ggcgccccga tcgtgacggc cgccgccgcg ctggagctgt tccacgcgtt
    10261 cgcgctgatc cacgacgaca tcctggacgg cagcgaccgc cgtcggggcg ggccgtcggt
    10321 gcacaggctc ttcgccgacc tgcacgcccg ctcgtcctgg cgcggcgacc ccgaggcgta
    10381 cgggcgcaac accgccctgc tctgcggcga cctctgcgcc gcctggtccg accagatgtt
    10441 ccacgagtgc ggcctggacc ccgggcgggt gcaccggggg tacgcggtct acgcgctgat
    10501 gcgtaccgag gtgatcgcgg gggagtacct ggacctggtc tccggggtgg gcgacgggtc
    10561 ggtggcgagc gcgctgaccg tggtgcggat gaaggcggcc cgctacacgg tcacccggcc
    10621 gttgcagatc ggcgcgacgc tggccggggc cgggccggag cgggtcgccg cgctggccgg
    10681 gttcggcgac ccgttgggcg acgcgttcca gttgcgcgac gacgtgctgg gggtcttcgg
    10741 cgacccggcg gtcaccggca agtcggtcct ggacgacctg cgggagggca agccgacggt
    10801 gatgatggcg ctggcccgtg gcgccgcgga ccgggtgcag gccgcgcggc tgcgggagct
    10861 gttcggcaac ccggcgctgg acggggacgg cgccgccgag ctgcggaaga tcatcgaagc
    10921 caccggggcc cgtgagcgga tcgaggggat gatccgggta cgcgccgagg ccgcgctcgc
    10981 ggccctggcg tccgccccgg tgaccgccga ggcccgcgcc gccctggccg ggctcgccgc
    11041 ccaggccgtc gaccggccct gctgagccgc cgcacaccgg cgactttccg cgatatcgac
    11101 gaaagttagt gccggatcgg cggaaggtat ggacacatcg atgtgcgccg cttaatgtcg
    11161 ggccatcacg aatgtgtttc gtcgaggtga accggcggcg cgggaaccca tcgactggtg
    11221 acctccgatc gatggggtcc gccccatccc tcgcaggtca cggccggccg ggcacggcac
    11281 ccggcgggcc gagcgcatcc cccgctacgg catccggcgc gacggcgcgc gcccgccctg
    11341 gcagtcactc gtcaggaagg gacggcacac ccatgtccac ccaggacgcc cccatccacc
    11401 ggctccgccg gcggctcagc gccgcctcgg cgctgctgct ggccgccacc gcgggcacgg
    11461 tcgccctcgg cgccggcccg gccacgctgg gcggccccac cccggccgag gcccaccccg
    11521 tcgtcggcac cgacttccag caggtcacgc tcgccaaggg cgtcgccgag gtcggcgagc
    11581 ccatgacgat agcggtgctg ccggaccggt cggtcctgca caccgcccgc aacggcacgg
    11641 tccggcgtac ggactccgcc ggcaccacct ccgtgatcgg cacggtgccc gtctacaccc
    11701 acgacgagga ggggttgcag ggcatcgggg ccgaccccaa cttcgccacc aaccggcaca
    11761 tctacctcta ctacgccccg ccgctggcca cccccgccgg ggacgcgccc gcgaccggca
    11821 gtgacttctc ggcctggcag ggcgtcaacc ggctctcccg gttcaccctc aacgccgact
    11881 tcacgatgaa caccggcagc aaggtcgaca tcctcgacgt acccgccgac cggggcatgt
    11941 gctgccacgt cggcggcgac atcgacttcg acgccgccgg caacctctac ctgtccaccg
    12001 gcgacgacac caacccgttc gactcggccg ggtacgcgcc catcgacgag cgcaccaacc
    12061 gcaaccccgc gtacgacgcg cagcgcagcg cggccaacac caacgacctg cgcggcaaga
    12121 tcctgcggat caaggtgaac gccaacggca cgtactcgat cccggccggc aacatgttcg
    12181 tcgactcgga cgcgcggacc cgccccgaga tctacgcgat gggcttccgc aacccgttcc
    12241 ggatgagcgt cgaccgggcc accggcatcg tctacgtcgg cgactacggc ccggacgccg
    12301 gcaccaccag cgcccggggc cccagcggcc aggtcgagtt caaccggatc accgggcccg
    12361 gcaactacgg ctggccgtac tgcacgggca ccaacaccgc caccgagacg tacgccgagt
    12421 gggacttcgc cgccgggacc gccggggcga agtacaactg ctccggcggg ccgaccaaca
    12481 actcgttccg caacacgggc ctgcccaccc tgcccggcgc gaagccggcc tggatccggt
    12541 acgccggcga cgccggcacc ccgccggagt tcggcggcgg ctccgagtcg cccatgggcg
    12601 gccccgtcta ccgctacgac gccgcgctca actccaccac caagttcccg cagtccttcg
    12661 acgggcagtt cttcgccggc gaactcggcc ggggctgggt gaagccgatc cacctcaacg
    12721 ccgacggcag cccgggaacc atcgacacgt tcccctggaa cggcaagcag atcatggaca
    12781 tggcgttcgg gcccgagggc gcgctctaca tcctcgacta cggcaccggc tacttcaacg
    12841 gcgacgccaa ctcggcgctc taccgctacg actacatcgc cggcggcaac cgggcgccga
    12901 ccgccgtcgc cgcggccgac aagacctccg gcgcggcccc gctgaccgtc aacttctcct
    12961 cagccgggtc cagcgacccg gagggcggga cgctcacgta ctcctgggcg ttcggcgacg
    13021 gcaccagctc gacggcggcc aaccccagca agacgtacac cgccaacggc acctaccagg
    13081 tcacgctgac cgtacgcgac ccccagggcg ccaccggcac ggcgaacgtg cagatcggcg
    13141 tcggcaacac cgcgcccacg gtcaccatcg acagcccggc caacggcaag ctgttcagct
    13201 acggcgacac cgtgccgttc agcatcaccg tgaccgaccc cgaggacgcc gccatcgact
    13261 gcaccaaggt caagatgacg tacgtgctgg gccacgacaa ccacggccac cagatcacct
    13321 cgaagaacgg ctgctcgggc tcgatcacca tccccgtcga cggtgaacac gacgacgcgg
    13381 cgaacatctt cgccgtcttc gacgccgagt acaccgacgc cggtgggctg accacgcaca
    13441 agcagcacac cctccagccg cgcaagcgcc aggcggagca cttcaagacc tcctccggcg
    13501 tcgggacctt cgacaaggcc acggccgagg gcggtaagac cgtcggcgac atccacaacg
    13561 gcgactggat cgcgttcgag ccgtaccgga tcgacaacgc gacctcgttc agcgcccggg
    13621 tctcctcggc cggcgccggc ggcaccctcc aggtgcgggt cggctcgccc accggcaccg
    13681 tgctcggctc cgccaccgtc ccggtcaccg gcgcctggga cacgttcacc accgtcagcg
    13741 gcagcatctc cggtgcgccg gccagcaccg ggaccctcta cctcacgttc gccggcgcgg
    13801 gcaccggcgc gctctacgac gtggacacgt tcgccttcac caccggcgcg gcgggggtcc
    13861 gcaccggccc ggtcgtcggg ctcggcggca agtgcctgga cgtgcgcaac gcggccacgg
    13921 ccgacggcac ccagatccag atctacggct gcaacggcac ggccgcgcag acgtggacgg
    13981 tgacgccgaa ctcgacggtg aaggcgctgg gcaagtgcct ggacatctcc ggcggcgggt
    14041 ccgccgacgg cacgaagatc cagctgtacg gctgcaacgg caccggcgcg cagaactggt
    14101 cggcccaggc ggacgggacg ctgaagaacc cgcagtccgg caagtgcctg gacgtctcgg
    14161 gcaacaaccc ggccgacggg caggccgtgc acctgtggac ctgccacacc ggcgccaacc
    14221 agaagtggac cctgccctga cctgaggcgg ggaggggccg ccgtgcccct ccccgccccg
    14281 gcgggccctc gacagccccg gcattggaga gcgacatgcg cagactcctc cgacccctcc
    14341 tcggcgcggc caccgccgtc ctcgccgtcc tcgcctgcac caccccggcc acccccgcca
    14401 gcgccgccga cgccccgtac gacgtgctgg tcttctcgaa gacggccggc ttccggcacg
    14461 actccatcgc ggtcggcacg caggcgatcc gcgacctcgg cgcggccaac aacttcaccg
    14521 tcaccgccac cgaggacgcc gcccagttca cgaccgccaa cctgtcccgc ttcgaggcgg
    14581 tggtcttcct caacaccacg ggcgacgtgc tcgacgccac gcagcagagc gccttcgagt
    14641 cgtacatcgg cgccggcggc gggtacgtcg gcgtgcacgc cgccgccgac accgagtacg
    14701 gctggtcctt ctacggcaac ctggtcgggg cgtacttcgc ctcgcacccg cacatccagc
    14761 aggcgaacgt caaggcggag aaccgggcgc acgcggcgac cgcgcacctg ccgcagacct
    14821 ggacccgcac cgacgagtgg tacaactacc agaccaacgc ccgctccacg gcccgggtgc
    14881 tggccaccct cgacgagtcc tcctactcgg gcggctcgat gggcgccgac cacccgcact
    14941 cctggtgcaa gacccacagc gggggccggt ccttctacac cggcggcggg cacacccagg
    15001 cgtcgtacgc cgagccggcc ttccgcgccc acctgctcgg cggcatccgg tacgcggccg
    15061 gccgggccaa ggccgactgc cggcccgaga gcgggtacac gccgctctac aacggctcca
    15121 ccaccggctg gtcgcaggcc gggccgggca gcttcagcaa cgccgacgcc accctcacct
    15181 cggtcggcgg gatgggtctg tactggtaca gcgcgaagca gttcaccaac tactcgctga
    15241 agctggactg gcggctcgcc ggcgacgaca actccggcgt cttcatcggc ttcccggcct
    15301 ccagcgaccc ctggtcggcg gtgaacaacg gctacgaggt gcagatcgac gccaccgacg
    15361 cggccgaccg cacgaccggc gccgtctaca ccttcaagtc cgccgacatc gccgcccggg
    15421 acgcggcgct caacccgccg ggggagtgga acacctacga actgctcgtc gagggcgagc
    15481 gcctccaggt cttcctcaac ggggtgaaga tcaacgactt caccaacacc gacccggtcc
    15541 gctcgctcgc cggccacatc gggctccaga accacggcac cggcgacgac gcgtcgttcc
    15601 gcaacatccg gatcagggaa ctcggcgtcg acccgccggg cgggaacacc accgtccagg
    15661 cggaggcgtt cagctcggcc ggcggggtcg ccccgttcgc caaggccggc gccaacggcg
    15721 ggcagaccct cggccacatc gacccgggcg actgggccgc gtacgccggg gtcgacctga
    15781 ccggggtgac gtcgctgcgg gcgcgggtcg tctccggcgg gccgggtggc accctccagg
    15841 tgcgtacggg atccacgacc ggcaccgtgc tcggctcggt cgccgtgccg aacacgggga
    15901 gctggaccac cttcgccgac gtcacgaccg ccctgtccgg ggtgccgtcc ggcacccggg
    15961 acctctacct gaccttcacc ggctcgggca cggggctctt cgacgtggac gacttcaccc
    16021 tggtcaggtc cggtggcagc ggcggcgtcg gtccgatccg cggcctgggc ggcaagtgcc
    16081 tggacgtgcg caacgcggcc acggccgacg gcacccagat ccagatccac ggctgcaacg
    16141 gcacggccgc gcagacgtgg acggtgacgc cgaactcgac ggtgaaggcg ctgggcaagt
    16201 gcctggacgt ctccggcggc gcctcggcgg acgggacgaa gatccagttg tggacgtgca
    16261 acggtacggg cgcgcagaac tggtcggccc aggcggacgg gacgctgaag aacccgcaga
    16321 ccggcaagtg cctggacgtc tcgggcaaca acccggccga cgggcaggcc gtgcacctgt
    16381 ggacctgcca caccggcgcc aaccagaagt ggaccctgcc ctgatccgct gaccctcccg
    16441 ttccgccccg cgatccggcg gtccggcccg gcacggtgtg cgcaccgggg gcggacagcc
    16501 gcaggatcgc ggggcggggc ggggctttcg tggggggccc ggtggtccta gagtgggggc
    16561 ggcgaccgtc gcggttgccg gtgaccggcg ggaggcgcaa cccgcccggt ccaggtgcgc
    16621 aggcacccac cggcgctccg cagcggcccg ccgtgtgccg gcccggccgg tcaccctcgc
    16681 cccggtcacg cacccacgga atcccccatc accacagggg agaagcacca tggcgcgacc
    16741 catcacgctc ttcaccggcc agtgggccga ccttccgttc gacgaggtct gccggctcgc
    16801 cgccgagtgg ggctacgacg ggctggagat cgcctgctgg ggcgaccact tcgaggtcga
    16861 caaggcgctc gcggacgact cgtacgtcga gcggaagcgg gagaccctcg cgaagcacaa
    16921 cctgaaggtc ttcgcgatct ccaaccacct ggtcggccag gccgtctgcg accacccgat
    16981 cgacgagcgg caccagggca tcctgcccgc ccggatctgg ggcgacggcg aacccgaggg
    17041 cgtacgccgc cgcgccgccg aggaggtcaa ggacaccgcg cgggcggcgg cgaagctggg
    17101 ggtcgacacc gtcgtcggct tcaccggctc gtcgatctgg cacacgctgg cgatgttccc
    17161 gccggtgccg ccgtcgatga tcgagcgcgg ctaccaggac ttcgccgacc ggtggaaccc
    17221 gatcctggac gtcttcgacg agacgggggt gcgcttcgcc cacgaggtgc acccgagcga
    17281 gatcgcgtac gactactgga cgacgaagcg gacgctggag gcggtcgggc accggcccgc
    17341 gttcgggctg aactgggacc cgtcgcactt cgtctggcag gagctggacc cggtgaactt
    17401 catcttcgac ttcgccgacc ggatctacca cgtcgactgc aaggacgcga aggtgcgtac
    17461 gggcgacggg cggcggggcc gactcgcctc gcacctgccg tgggcggaca tgcggcgcgg
    17521 ctgggacttc gtctccaccg gccacggcga cgtgccctgg gaggactgct tccgggcgct
    17581 gaacgcgatc ggctacgccg gcccgatctc gatcgagtgg gaggacgcgg ggatggaccg
    17641 cctcgtcggc gccccggagg cgttgcagtt cgtccgccgg ctcgccttcg acgccccggc
    17701 cgcggcgttc gacgccgcgt tcagcagcaa ggactgaccg ctccgggcct acccgggcgg
    17761 gccgggaccg agggtcaggc agccgggcgg gccggcgtcg agggtcccgc acccgggcgg
    17821 gcctgcgtca gcgggcgcac acgggggcgg ccggcggcag cgggcaacac ccgagcgggc
    17881 cgggcgcccg aaggcgtccg gcccgctcgg aggtgcgatc agagggtgct gccgttggtg
    17941 cccgagctgg acggcttgct acggggcgtg gtggtggccg acgtcgaccc gggggtcgcg
    18001 ctcgtgctcg acgacccgga ggcgctcttc gcgccgaccg tggccggcgt gccggcgaac
    18061 gcgtcgtcgg cggcggtcag ctcctgcttc tggccgttgg tgctcagctt ctcgcccagc
    18121 ttcgactggc cgagcttgtc cttgccctcg ctgtagaggc gggtcgcctg ggcctgcgcg
    18181 acaccggccg cctcctggac ggtcgggtgg tcgagcacct tgcggccccg gatcaccagc
    18241 tcctcgtact tctcccgacc ggcacgggcg cccaggacga atcccgcagc cagcccgcca
    18301 aggaacatca tctttccgcg catggcggct ccttccgtac ctgacgcgcc gtcgtccggc
    18361 gggctacccc accggaggcg accaaatcgc gcctgtcttc tctgtccgca gctaactacc
    18421 catcctgctc tccgctcata cctccttgtg ccgggatgac gatttgtctc ggtttattat
    18481 cgtctggccc agggaacggt tccgggggta accccctgga ccgacacccc ccggaatcct
    18541 gtactcttgt ccccgtcgca cggcgcagcg aaatcggcgc cggacgacgc aacggtcccc
    18601 cgtagctcaa ttggcagagc agccggctgt taaccggcag gtttttggtt cgagtccaaa
    18661 cgggggagct tccacacctg acgcccgtcg gccacgccgg cgggcgttcg ccgttcccgc
    18721 ctccgtgacc cgttcccgcc ccgtgacccg tttccgtcac cccgggcccg ctcgcccggc
    18781 aggatggtcg atgtcgactt ggactcccgc tgcgtcgatt gatacgtcga ttcatggggt
    18841 gggtacggat gcccggaaga ggtggccacg gcaggatcac gctcgtcgcc gtggcggtcg
    18901 tgctggcgtg gctggtcgtc ggggcggtcg ccggtccgta cgccggcagg ctcagcgagg
    18961 tcgccaccaa cgacaacgcc tccttcctgc ccgccgaggc cgaggccacc cgggcgcagg
    19021 agctgtccgc ccggttcgtc gagcgaccga ccacccccgc cctcgtggtc tacgaacgtg
    19081 ccggcggcct caccgacgcc gacgcgcagc gggtggccgc cgacgccgcc cggttcgccc
    19141 gggtgcccgg cgtcgtcggc ccgctgccgc cgccgatccc cagcgaggac gggcaggcgc
    19201 tacaggtggt cgtacccatc gacgacgccg acggcgaacg gatcggcacg gtcgtcgagg
    19261 aactgcgcgc gatcgccggc gacgaccgcg acgggctcgg cgtggacgtg gccggccccg
    19321 ccggcctgct cgccgacctg atcgaggtct tctccgccat cgacggcacc ctgctgatcg
    19381 tcaccctctg cgtggtgctg gtcatcctgc tcgtcgtcta ccgcagcccc gtcctgtgga
    19441 tcttcccgct gctctccgcc gggatgtcct tcgcgctggc cgcggtcttc gtccacctgc
    19501 tcgccgacgc cgacgtgatc aagctcaacg ggcaggcgca gggcatcctc accgtgctcg
    19561 tcttcggcgc cggcaccgac tacgcgctgc tgctggtcgc ccgctaccgg gaggaactgc
    19621 accggcacga gcgcccctgg gacgccatgc gggcggcctg gcgaggcgcc gcgccggcca
    19681 tcgtcgcctc cggcggcacg gtcatcgtga gcctgctctg cctgctgctg tccagcctga
    19741 actcgaaccg ggcgctcggc cccgtcgccg ccatcggcat cggcgccacc ctgctggtca
    19801 tgctgacgtt cctgcccgcc ctgctggtgc tgggcgggcg gtgggcgttc tggccgcgcc
    19861 gccccccccg tacgaccggg ccgacccccg ggccgagcac ggcatctgga gccggatcgc
    19921 cggcttcgtc gcccggcggg cgcgacccgt ctggctgctc accaccctcg ccatggccgc
    19981 gctcgcactc ggcctgacgc agctcggcgc gaccacgctc ggccagtccg acctcttcac
    20041 cgggcgcacc gactcggtcg ccgggcagga ggtgatcgcc cggcactacc cggccggcac
    20101 cggcagcccc gccaccatct tcaccacccg cgacaccgcc caggaggtcg cccgggtggc
    20161 ccggggcgtg ccggggatcg ccaccgtacg acccgtcacc gcccaccgga ccggcccgcc
    20221 cgacccgaac gcgccccccg ccgtcgtcga cgacaccgtg cagttggagg cgacgctcgc
    20281 cgacccgccc gacagcgacg gcgccgagcg ggccgtccgc gcgctgcggg cggcggtgca
    20341 cggcgtaccc ggctccgacg ccgtcgtcgg cggcttcacc gcgatcaacg tggacacctc
    20401 cgccgcctcg acgcgggacc gcaacgtgat cattcccgtc gtgctggtgg tgatcgcgat
    20461 catcctggcc ctgctgctgc gggcgctcct ggcgccgctc ctgctgatcg ccaccgtcct
    20521 gctgagcttc gccgccacgc tcggcctctg cgcgctggtc ttccggtacc tcctcgactt
    20581 ccccggcgtg gacgcctcgt ttcccctctt cgccttcgtc ttcctggtcg ccctcggcat
    20641 cgactacaac atcttcctga tgagccgcgt ccgcgaggag tccgtccggc ggggcacccg
    20701 ggccggcgtg ctcgccgggc tcgccgtcac cggcggcgtg atcacctccg ccggcatcgt
    20761 gctcgccgcg accttctccg cgctggccgt actgccgctg gtggtgctgg tcgagctggg
    20821 cgtcgcggtc gcggtcgggg tgctgctcga caccatcgtc gtccgctcgc tgctggtgcc
    20881 cgcgctggcg tacgacatcg ggccgaagat ctggtggccg ggccggctgt cccggacgaa
    20941 cggagagcgg gaggcgcgag atgctcgctg agaccgacgt gatcgtggtc ggcggcggcc
    21001 tggccgggct cgccgcggcc cggcggttgc accgcgccgg cgtgccgtgg cggctgctgg
    21061 aggcc
//
