LOCUS       NZ_FMHJ01000014        21155 bp    DNA     linear   CON 28-JUL-2024
DEFINITION  Streptomyces sp. WMMB 714, whole genome shotgun sequence.
ACCESSION   NZ_FMHJ01000014
VERSION     NZ_FMHJ01000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. WMMB 714
  ORGANISM  Streptomyces sp. WMMB 714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900090125.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 02:17:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,656
            CDSs (total)                      :: 5,578
            Genes (coding)                    :: 5,496
            CDSs (with protein)               :: 5,496
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 4 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 15 of 82
            Pseudo Genes (incomplete)         :: 72 of 82
            Pseudo Genes (internal stop)      :: 4 of 82
            Pseudo Genes (multiple problems)  :: 8 of 82
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 64398
            Orig. end                         :: 85553
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMHJ01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21155
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21155
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21155
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11155](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11155)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1159..1173
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(1456..1470)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            1566..2930
                     /locus_tag="H181DRAFT_RS23105"
                     /old_locus_tag="H181DRAFT_04659"
     CDS             1566..2930
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157789.1"
                     /locus_tag="H181DRAFT_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04659"
                     /product="MFS transporter"
                     /protein_id="WP_045866329.1"
                     /transl_table=11
                     /translation="MATPPVEKPVPDERTGLRRVLISSFAGTSIEWYDFFLFGSAAALV
                     FPHVFFPGSDPATGTLLSFATYAVAFLARPLGGIVFGRMGDVVGRKKALIATLFLAGGG
                     TFLMGCLPGYDAIGVTAPVLLVLLRLVQGLGLGGEWAGAVTLSAEHAEAGGKRHRRGIL
                     TSWTQLGVPAGNLVAVGALTAASTALPDDAFLSWGWRLPFLASAALVAAGWWMRVKVEE
                     SPLFEAAEPARAPIREVLSTHWRQVLLTVGMRIASDVSYYVFAVFALAYLSGTLGLPRD
                     WGLYAVIVGSVLQLAVIPASAAASDRYGRRPVYIAGSLAVAAGALVAWPMIETRSLAGV
                     LAAVSIGLVAQAVMYGPMAAFITELYSTRLRCSGSSFGYQVAGIAGGAPAPLIAALLVD
                     RFHTTTAVSLYVVATALIAALSAYLAKETRWNRLDQDTGTPAPAPAVAPATGEPS"
     gene            2927..4150
                     /locus_tag="H181DRAFT_RS23110"
                     /old_locus_tag="H181DRAFT_04660"
     CDS             2927..4150
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012766.4"
                     /locus_tag="H181DRAFT_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04660"
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="WP_045866330.1"
                     /transl_table=11
                     /translation="MNDTAVATIRRRLAEEGLSGYVAVTPSNLFYVTGFRSYFVSEWWR
                     MHGTVFALVPADPRKPVTVVLGDFEEKTARAAAPDVELRTYRLWVDLNTAEEMAADPSG
                     AQPASRPEQYDDGELDGVLASALRESGMDQGRVATDMQHLPVPALRRLERCAPGAGWED
                     FTDDIYRVRLVKQPWEVERLALGVELSELGMASAVKHLEEGMTAHDVRLLYQSGVTRAA
                     LDDARFAGYTDNWVLPAVGSRTSAGYGAREGRLAAGDLVKFDCGTTVGGYRCDGGRTFA
                     YRHRTARAERLYGVLAEAQRIARSMIRPGTVVGDVFRAAVHHVHSNGFPSYTRGHVGHS
                     VGIDTFHEEPPYISPSSGTVMEPGMVFAVEVPSYTPDVGAVMIEDMLVVTEDGSRLLHG
                     LPHELAVA"
     gene            4150..5043
                     /locus_tag="H181DRAFT_RS23115"
                     /old_locus_tag="H181DRAFT_04661"
     CDS             4150..5043
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="H181DRAFT_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04661"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_045866331.1"
                     /transl_table=11
                     /translation="MELRLLQALVAVADELHFGRAARRLGIAQPPLSQRIRRLEHELDV
                     RLFERNRQGVSLTTAGAELAEQARRVIAGAEHVEKLAYNIRSGGAGTLRVGAVGSAFYQ
                     ALPALLAPARERLPELSLHIREMETPQLITALLSAELDVALLRPPAGRGLRSRTVWREP
                     LVLALPEGHPLAGEPEVHTRLLDGEPLVLFPRDSGPGYWDRVETLLRAADIALEPVAEA
                     DHVTTMLGLVALGVGLSIVPASARVLRLTGVRYVPLQPRTELPLAAVVNPETLTPAVDR
                     FLTTLPRKPVLAGDPE"
     gene            5257..6012
                     /locus_tag="H181DRAFT_RS23120"
                     /old_locus_tag="H181DRAFT_04662"
     CDS             5257..6012
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308020.1"
                     /locus_tag="H181DRAFT_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04662"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_045866332.1"
                     /transl_table=11
                     /translation="MFTPQGPSLRELARQALSSVEHGYDLLAPKFDHTPFRTPDSLLCA
                     VRRALAEIGPFEHGLDLCCGTGAGMTVLREVCRRSVTGVDFSAGMLEAGRERAALPHPS
                     PGDARGAGAPAVSWVRGDVHALPFKPVFDLVVSFGAFGHFLPHELDGVFAQAHSVLRPG
                     GRFAFPLPAPATPRSSWYWAALGFDAAMRVRNALWRPPFVMYYRPFRLGLARRKLEQAG
                     FTVELCALPEFGRRADGSPRCRMVVATRT"
     gene            6199..6867
                     /locus_tag="H181DRAFT_RS23125"
                     /old_locus_tag="H181DRAFT_04663"
     CDS             6199..6867
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017534.4"
                     /locus_tag="H181DRAFT_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04663"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_045866333.1"
                     /transl_table=11
                     /translation="MDGDREADANRLAAESAARNDPTGWFEKLYAQAAAGEAVVPWNRD
                     APNPLLVGWAEQSGVAGAGRRALVVGCGLGQDAEYTARLGFRTTAFDISPTAVRQARES
                     FPGSAVDYVVADLLDPPGEWAGAFDLVVESVTVQSMPLSVRARAIGNVAKMVAEGGELL
                     VIAGAREEGEQVDGPPWPLTRTEVDSFAVRGLHTAWVERVAHPDAFEQRHWRARFLRTT
                     "
     gene            complement(6910..7116)
                     /locus_tag="H181DRAFT_RS23130"
                     /old_locus_tag="H181DRAFT_04664"
     CDS             complement(6910..7116)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_04664"
                     /product="hypothetical protein"
                     /protein_id="WP_074468009.1"
                     /transl_table=11
                     /translation="MFPVAGPMIVEVTRRHAGSALPDAPQIPEEPRPPGRSRHTLARAL
                     RRLADRLEPPRCTADHALRPHPQ"
     gene            complement(7252..8325)
                     /locus_tag="H181DRAFT_RS23135"
                     /old_locus_tag="H181DRAFT_04665"
     CDS             complement(7252..8325)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="H181DRAFT_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04665"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_045866335.1"
                     /transl_table=11
                     /translation="MEPRTTRATLQTVADEVGVSRTTVSNAYSRPDQLNSALRERILEA
                     ARRLGYPGPDAAARSLRRGRAGAIGLVFTETLSYAFADPYSVGFLRGVAEVAESSGTGL
                     LLIPMPPGTDEAETAMRDAVVDGFCLYCMPVRHPAKKVIQARGLPVVTTDENDDPSIPH
                     VGIDERASARLAAEHLARLGHRRVAVMVDHVVEPGHAGPATVEEQRVSECAVLHGRLAG
                     YREVLEEAGVDWADVPVVAAGRNSRPAAAAAAAHVLDVADRPTAVLATGDVLALGVLDA
                     CEQRGLVPGRDISVAGFDDVPEAARARLTTVRQPMGEKGRRAARLLLEPRDPGEAVPRV
                     QLPTELVVRATTGPAPR"
     misc_feature    complement(8356..8374)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            complement(8459..8995)
                     /locus_tag="H181DRAFT_RS23140"
                     /old_locus_tag="H181DRAFT_04666"
     CDS             complement(8459..8995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354686.1"
                     /locus_tag="H181DRAFT_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04666"
                     /product="Dps family protein"
                     /protein_id="WP_045866447.1"
                     /transl_table=11
                     /translation="MSQQDGGDVIQLLKTRLHALNDLALTLKHIHWNVVGPHFIAVHEM
                     LDPQVDSVRDMTDTTAERISTLGGSPHGTPGAIVEGRHWEDYTIGRAESIEHLGALDLV
                     YTGIIEDHRAAVRATAESDPVTQDMLIEQLRGLELYQWFVRAHLESAGGALSTSSASSE
                     REAASQAGEQARRQP"
     gene            9223..9996
                     /locus_tag="H181DRAFT_RS23145"
                     /old_locus_tag="H181DRAFT_04667"
     CDS             9223..9996
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944614.1"
                     /locus_tag="H181DRAFT_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04667"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_045866448.1"
                     /sec_met_domain="PCMT (E-value: 4.3e-06, bitscore: 20.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLHDSGLTRAFDRAAGAYDPLTALNPGYHRHLRRAAERMLTGD
                     QRARGGDGMRVLDLGCGTGASTAAVLRAAPKARIVAADASAGMLERAGAKAWQGDVTFV
                     RAPAEGLEEAGVRGPFDAVFAAYLVRNLSEPDAVLRDLRRMLGPGGRLAVHEYTLSGAA
                     VHRAVWSAVCRGVIVPLGSLGPGGGRLYRHLWRSVLAFDTAGAFALRLRSAGFESVRCD
                     AVRGWQRGIVHTFHATVPAASREAAAEEAGTGGRP"
     gene            complement(10001..11155)
                     /locus_tag="H181DRAFT_RS23150"
                     /old_locus_tag="H181DRAFT_04668"
     CDS             complement(10001..11155)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="H181DRAFT_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04668"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_139131752.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-44, bitscore:
                     146.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRRPSAHVHEASHDAPPHALGADPDQDTAAVIGTLLERYLAQRR
                     EEAARSSEQFARDVIDVLVDVVLRGGKRTRPAFLWWGWRGCGGESRGANAEAVLKVATA
                     LELLQACAVIHDDLMDGSPSRRGAPAAHVAFADRHRAAGLRGDPDDFGAYAAVLAGDLA
                     LVWAHDLFESAGLDAKARRAAAPAWQAMRTEIIAGQYLDLYGQSTGVDSPEESLRVAYL
                     KSGLYTVERPLHLGAAIAGAGPDLIASLRRAGRSAGVAFQLRNDLVGVFGSDGSGEPSG
                     DDIKDGASTYLTAIALQRARAHSRHEAERQLRDAIGNRDLSPEDLRRVRDLLTRLGAAD
                     AVEARIEQLTADALTVLEQARLRAPAHERLPALVRRVVEKRPAG"
     gene            11595..11954
                     /locus_tag="H181DRAFT_RS23160"
                     /old_locus_tag="H181DRAFT_04669"
     CDS             11595..11954
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006137072.1"
                     /locus_tag="H181DRAFT_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04669"
                     /product="DUF3140 domain-containing protein"
                     /protein_id="WP_045866337.1"
                     /transl_table=11
                     /translation="MSDTEQRTQREQLFTDFEKSVNMPAGQLERWLATSESRNVGRHKG
                     QSESHGHAAGRRIVRLLRTRRADFTADDLVHMRRAVRHIERQLRHRPRGDVSDTAWRFS
                     LMNWGHDPQRHDQAR"
     misc_feature    complement(11644..11659)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.28"
                     /tool="antismash"
     gene            12014..13549
                     /locus_tag="H181DRAFT_RS23165"
                     /old_locus_tag="H181DRAFT_04670"
     CDS             12014..13549
                     /EC_number="6.5.1.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0071897 - DNA biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838664.1"
                     /locus_tag="H181DRAFT_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04670"
                     /product="ATP-dependent DNA ligase"
                     /protein_id="WP_045866338.1"
                     /transl_table=11
                     /translation="MLLAEVARTSQEITTVSSRKEKVGILARMFRRASPEEVPLVVTYL
                     AGRLPQRRTGVGFSALSGRHPPAAAAQLTVAAVDGALTEIAAVRGKGAQTERARLLAAL
                     MSAATEEEQHFLFRLLTGELRQGALDAFAVEGLAEAVGAPPARVRRAVMFGGSLGAVAR
                     ALLEDGPSALGRFELQTGRPVLPMLAQSAKNVLEALTKLGPSVVEEKLDGIRVQVHKDG
                     DSIALYTRTLDDITDRLPEVVAAAGDLAARQAVLDGEVIALDGHGRPRPFQETSQRVGS
                     QLDVATARTTLPVTPRFFDVLSVDGRDVVDLTVRERHAALARVVPEELRVRRLVLEDPG
                     SAEQRAAAEEFAREVLEQGQEGVMVKALDSSYSAGRRGAAWLKVKPVHTLDLVVLAAEW
                     GHGRRTGMLSNLHLGARRPDGSFAMLGKTFKGLTDKLLAWQTEQLRAIAVAEHPWGVEV
                     RPELVAEIAVDGLQRSTRYPAGVTLRFARVLRYRTDKTAAEADTVDDVLALRR"
     gene            complement(13649..14698)
                     /locus_tag="H181DRAFT_RS23170"
                     /old_locus_tag="H181DRAFT_04671"
     CDS             complement(13649..14698)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542938.1"
                     /locus_tag="H181DRAFT_RS23170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04671"
                     /product="phosphatidylinositol-specific phospholipase C
                     domain-containing protein"
                     /protein_id="WP_045866339.1"
                     /transl_table=11
                     /translation="MSRPRLAVAVSAAALVTAAAAVAVPLSAQAGPEAAAASYGETTSV
                     GVHNAYEKDKYEYFADALDSGASLLELDVWTNIVGKGWRVSHSNPTGNDNNCGNAESAA
                     ELRSNKRDQALDGCLADMRAWHDANPGHPPVLIKVEMKDGFYDKADRGPDELDALLGEK
                     LGDALLRPADVVGDHATLDEAVGASGWPDRDALAGKFVIELIPGTLEEGNPADDLWTDE
                     EYATHLKDLAGKGTLAEAGAFPAVHGAEKGDPRTERYEEALRPWFVLFDGDASTFTGGE
                     IDTAWYRENGYLVVMTDAHKVAPEIDGTSPTEEEAGDRLTQLAASHASFITSDWAKLPS
                     VLSKVVPRG"
     gene            complement(14875..15141)
                     /locus_tag="H181DRAFT_RS23175"
                     /old_locus_tag="H181DRAFT_04672"
     CDS             complement(14875..15141)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569422.1"
                     /locus_tag="H181DRAFT_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04672"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_045866450.1"
                     /transl_table=11
                     /translation="MEIAGIISAIVIGTVIGVLGRLIVPGRQRVGILLTIGVGIVAALV
                     GSAIATYFGVGDTKSVDWIEWLIQLALAALGVAALDRSKRRRR"
     gene            15342..16019
                     /locus_tag="H181DRAFT_RS23180"
                     /old_locus_tag="H181DRAFT_04673"
     CDS             15342..16019
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018519337.1"
                     /locus_tag="H181DRAFT_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04673"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_045866340.1"
                     /transl_table=11
                     /translation="MDALLPRPPVNLGPGAVHVPGWLGIEQQRSLVAACREWACGPVPL
                     RHTKLPRGGVMSVRTVCLGWHWQPYRYSRTADDVNGRRVAELPEWLADLGRRAVAATAG
                     HDDARGEGWTSGRYDPDTALVNFYDGRAKMGMHQDKDERSGAPVVSLSIGDSCRFRFGN
                     TAGRGRPWTDVELASGDLFVFGGPARYAYHGVTRVFEGTGDPATGLAPGRLNLTLRVTG
                     LSG"
     gene            16098..16328
                     /locus_tag="H181DRAFT_RS23185"
                     /old_locus_tag="H181DRAFT_04674"
     CDS             16098..16328
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004019.1"
                     /locus_tag="H181DRAFT_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04674"
                     /product="DUF6480 family protein"
                     /protein_id="WP_045866341.1"
                     /transl_table=11
                     /translation="MDEKYPDPDEPGHTPGLEPGGQVPPGETPPGEDSTAGAGPDERHN
                     PPKGWAKAPVIIIGVLVLLFLIYFVAWAVEL"
     gene            complement(16981..18423)
                     /gene="gndA"
                     /locus_tag="H181DRAFT_RS23195"
                     /old_locus_tag="H181DRAFT_04675"
     CDS             complement(16981..18423)
                     /EC_number="1.1.1.44"
                     /GO_function="GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gndA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848256.1"
                     /locus_tag="H181DRAFT_RS23195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04675"
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="WP_045866342.1"
                     /transl_table=11
                     /translation="MSTTAHIGVTGLAVMGRNLARNFARNGYTVAVHNRTAARTRDLVR
                     DFGDEGSFVAAETAEEFVAALERPRRLIIMVKAGAPTDAVIDEFAALLEPGDVIIDGGN
                     AHYADTRRREADLRERGLHFVGAGISGGEEGALHGPSIMPGGSAEAYESLRPMLESVAA
                     KAEDGTPCTTHVGPDGAGHFVKMVHNGIEYADMQLIGEAYHLLRDVAGFSPARVAETFR
                     QWNTGRLDSYLIEITAEVLSHTDAETGKPFVDVVADQAEQKGTGRWTVQTALDLGVPVS
                     GIAEAVFARSLSGHTDLRSASGHLPGPAASALAPEEAERFAEKVEQALYASKITSYAQG
                     WNMIRSGSEEFGWGIDPGAVGAIWRAGCIIRAAFLDRIRSAFAARPDLPTLLADDHFGK
                     EIGEAQGDWRSVVATAVEHGVPVPGFSAALASYDALRSERLPASLTQAQRDFFGAHTYR
                     RTDRDGSFHTLWGGDRSEVPSD"
     gene            complement(18493..19080)
                     /locus_tag="H181DRAFT_RS23200"
                     /old_locus_tag="H181DRAFT_04676"
     CDS             complement(18493..19080)
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933644.1"
                     /locus_tag="H181DRAFT_RS23200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04676"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_045866343.1"
                     /transl_table=11
                     /translation="MGQVYEHIDDGVRAFIEKQHVFFVATAPLAADGHVNLSPKGLAGS
                     FAVLDDRTVAYLDLGGSGAETVAHLRENGRVTIMWCAFEGPPRILRIHGRGTPVFRDDP
                     RWARLLPHFGEEMRARTDLRAVITVEAERISDTCGFAVPFMEHQGERPLHTQRFARETA
                     DSFAAYCEKKEHVGVSLDGLPGLPLPLPPRTL"
     gene            complement(19209..20009)
                     /locus_tag="H181DRAFT_RS23205"
                     /old_locus_tag="H181DRAFT_04677"
     CDS             complement(19209..20009)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016162.4"
                     /locus_tag="H181DRAFT_RS23205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04677"
                     /product="DUF427 domain-containing protein"
                     /protein_id="WP_045866344.1"
                     /transl_table=11
                     /translation="MSLTLGGGPLASRPPATVNYSIDGPAHRLLWQPFPRRVRALLSGE
                     EVLESDNAKLLHESNLLPQVYVPASDVRPELLEESPHTTHCPFKGDARYWSVRAGERLA
                     ENAVWGYPEPLPGAEWLRGHVAVYWASMDTWFDEDEEAVGHIRDPYHRVDVRPTSRHVV
                     VEAAGRQVAESKRAMLLSETGLPNRYYLPQSDVRGELLERSATRTHCPYKGQASYLTVR
                     DGATAIEDAAWCYEKPLDEARRVARHLCFLADGVQTFVDGEPLA"
     misc_feature    complement(20003..20013)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            20212..20415
                     /locus_tag="H181DRAFT_RS23210"
                     /old_locus_tag="H181DRAFT_04678"
     CDS             20212..20415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010264175.1"
                     /locus_tag="H181DRAFT_RS23210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04678"
                     /product="hypothetical protein"
                     /protein_id="WP_045866345.1"
                     /transl_table=11
                     /translation="MDTAKLELAARRCREAEEALEAARSDLRTEAVVALRGADRDGQAA
                     VSRITGWSRAYLRKLMRADRAG"
     gene            complement(20496..21128)
                     /locus_tag="H181DRAFT_RS23215"
                     /old_locus_tag="H181DRAFT_04679"
     CDS             complement(20496..21128)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061808.1"
                     /locus_tag="H181DRAFT_RS23215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_04679"
                     /product="response regulator transcription factor"
                     /protein_id="WP_045866346.1"
                     /transl_table=11
                     /translation="MRVVIAEDNVVLAEGLALLLRAEGHEVLAQVSCGEALVDAVLGER
                     PDVAVVDVRLPPSFRDEGLRAALRIRRERPGQPLLVFSQYVERSYALELLSDRAGGIGY
                     MLKDRVARVEEFLRALEHVAAGGTSMDPEVVSQVLARHDPLTALTGREREVLRLMAQGF
                     ANGEIARRLVVTERAVHKHVGNIFAKLDLPVEDSGHRRVLAVLAYLS"
ORIGIN
        1 cccggcggcc ccaacccgcc cgtcgggaag cagcggctgg agcccgaggg catctggtac
       61 acgccctcgt cgggcatctg gcagaccgtg tggatggaac ccgtcgccgc ggagcacacc
      121 accgacgtca agacgacgcc ggacgtgagc ggtgagcagg tgagcgtgac ggcgcgcggc
      181 gtgcccgacg gtgtgcccgt cacggcggtg gcgtacgacg aacggggcgg tgagaagggc
      241 gccgggagca agggccggga ggtcggacgg gccaccggca gcggcgacac ccccttcgac
      301 gtccccgtgc ccgatcccga gctctggtcg cccggcgatc cgcacctcta cacgctgaag
      361 gtgaccgtcg gggaaggggc ctccgccgac accgtcgaga gctacttcgg catgcgcgag
      421 atcggcgtcg agaccgtcga cggcaagcgg cgcatggtgc tcaacggcga gccggtcttc
      481 tccatggcca cgctcgacca gggcttctgg ccggacggcc tgcacacccc gcccacggac
      541 gaggccctcg cccacgaact ggaggcgcac aagaagctcg gcttcaactc ggtgcgcaag
      601 cacatcaagg tggaacccga ccgctggtac taccacgccg accggctggg cctgctggtg
      661 tggcaggaca tgccgtccat gcgctcggac cgcacaccgg accgggccgc gcgggagcag
      721 tacgagcacg agatgaagcg catgatcgcg cagcacgaca gccacccctc ggtgatcatg
      781 tgggtcacct tcaacgaggg ctgggggcag tacgaccagg ccaggatcgc cgactacgcc
      841 aaggggctcg acccgacgcg gctggtgaac aacatgagcg gccacaactg ctgcggtgcc
      901 gtcgacggcg gcaacggcga catctccgac gcccacggct atcccggcgc gcaactgccc
      961 gaacccgacg gccggcgcgc gctggtcagc ggcgagtacg gcggactcgg ccttgcggtg
     1021 cccgggcacg cgtggccggt gcgccacacc tacgtcggcg tcgagaagga ggagttcacc
     1081 gacgagtacc tcgcgaagct ggaggacatc gagcagttcg ccgcatgcga cggcagcagc
     1141 ggcgccgtct acacccagat caccgacctc gaaggggagt tgaacggcct gctgacctac
     1201 gaccgcaagg tcgccaaggc cgacggcgaa cgtctcgccg cggcgcacgc cgccctgctg
     1261 aacggcgccg ccgagggcac gctgacctgc gaacgggagt aggaagcccg gccaggtggc
     1321 cgtcgcggcc ctccggccgg ggccgcgacg gctgaggcgg gtgcctagac gggaggtgcg
     1381 aggcggcgag acgtgcgagg cggagggtgc gaggcgtggg tggtgcgcgc gggcgacggc
     1441 cgctccggtg ggcagttcgc cacccgtgat accgaacgcg tatcacgaga gccgcatctg
     1501 atattggacg ccgcaattcc gcattcttac ggtggggcga acgacgccca cgccgaggag
     1561 gccgcatggc cacacccccc gtcgaaaagc ccgtacccga cgagcgcacc ggcctgcgtc
     1621 gcgtcctgat ctccagcttc gccggtacct cgatcgagtg gtacgacttc ttcctcttcg
     1681 ggtcggcggc cgcgctggtc ttcccgcacg tcttctttcc cggcagcgac cccgccaccg
     1741 gcacgctgct ctccttcgcc acctacgccg tcgcgttcct cgcccgcccg ctcggcggca
     1801 tcgtcttcgg gcgcatggga gacgtcgtcg gccgcaagaa ggcgctcatc gcgacgctct
     1861 tcctcgccgg cggcggcacc ttcctcatgg gctgcctgcc cggctacgac gcgatcggcg
     1921 tgacggcgcc cgtgctgctc gtgctgctgc gcctcgtcca gggcctcggc ctgggcggcg
     1981 agtgggccgg ggcggtgacc ctgtccgccg agcacgcgga ggcgggcggc aaacggcacc
     2041 ggagggggat cctcacctca tggacgcagc tgggcgtccc cgccggcaac ctcgtcgctg
     2101 tgggtgcgct gactgccgcg agcacggcgc tgcccgacga tgccttcctc tcctggggat
     2161 ggcggctgcc gttcctggcg agcgcggccc tggtcgccgc cgggtggtgg atgcgggtga
     2221 aggtcgagga gtcgccgctg ttcgaggccg ccgaacccgc ccgggcgccc atccgcgagg
     2281 tgctctcgac gcactggcgc caggtcctgc tgacggtggg tatgcgcatc gcctccgacg
     2341 tgtcgtacta cgtgttcgcc gtcttcgcgc tggcatacct ttcgggaacg ctcgggctgc
     2401 cgcgcgactg gggcctgtac gccgtgatcg tgggttccgt gctgcagctc gccgtcatcc
     2461 ctgcgtcggc ggccgcctcg gaccgctacg gccgccgccc cgtctacatc gccggttccc
     2521 tcgccgtcgc ggcgggcgcc ctcgtggcgt ggccgatgat cgagacccgc agcctggcgg
     2581 gggtcctggc cgcggtgagc atcgggctgg tggcacaggc ggtgatgtac gggccgatgg
     2641 ccgcgttcat caccgagctg tacagcacgc ggctgcgctg ctccgggtcc tccttcggct
     2701 accaggtcgc cggaatagcc ggcggcgctc ccgcaccgct gatcgccgcc ctcctcgtcg
     2761 accgcttcca caccaccacg gcggtgagcc tctacgtcgt ggccaccgcc ctcatcgccg
     2821 ccctgagcgc ctacctggcg aaggagaccc gctggaacag gctcgaccag gacaccggca
     2881 cgcccgcacc cgcacccgcc gtcgcacccg ccaccggaga gccgtcttga acgacaccgc
     2941 cgtcgccacg atccgccgcc gcctcgctga ggagggcctg tcggggtacg tcgctgtgac
     3001 gccctcgaac ctcttctacg tcaccgggtt ccgcagctac ttcgtctccg agtggtggcg
     3061 gatgcacggc accgtcttcg cgctggtccc cgctgacccg cggaagcccg tcaccgtggt
     3121 gctcggcgac ttcgaggaga agacggcccg agccgccgca cccgacgtgg agctgcggac
     3181 ctaccggctg tgggtggacc tcaacacggc cgaggagatg gcggcggacc cgtccggcgc
     3241 gcagcccgcc tcacgccccg agcagtacga cgacggcgag ctcgacggcg tcctcgcctc
     3301 cgcgctgcgc gagtcgggca tggaccaggg ccgggtcgcg acggacatgc agcatctgcc
     3361 cgtaccggcg ctgcgccggc tggagcggtg cgcgcccgga gcgggctggg aggacttcac
     3421 cgacgacatc taccgcgtac ggctcgtcaa gcagccgtgg gaggtggagc ggctcgcgct
     3481 gggcgtggag ctgtcggaac tcggcatggc cagcgccgtg aagcacctgg aggagggcat
     3541 gacggcgcac gacgtgcggc tgctgtacca gtcgggcgtc acccgggccg cactggacga
     3601 tgcgcggttc gccggctaca ccgacaactg ggtcctgcct gcggtgggtt cccgtacgtc
     3661 cgccggctac ggggcgcggg aggggcgtct cgccgcgggg gacctggtga agttcgactg
     3721 cggcacgacg gtcggcggct accgctgcga cggcgggcgg accttcgcct accggcaccg
     3781 caccgcgcgg gcggagcggc tgtacggggt gctggcggag gctcagcgca tcgcccgctc
     3841 catgatccgg ccggggacgg tcgtggggga cgtcttccgg gcagccgtcc accacgtgca
     3901 cagcaacggc ttcccctcct acacgcgggg ccacgtcggg cactccgtgg ggatcgacac
     3961 cttccacgag gagccgccct acatcagccc ctcgtccggg acggtgatgg agcccgggat
     4021 ggtcttcgcc gtcgaggtgc cctcgtacac acccgacgtg ggtgcggtga tgatcgagga
     4081 catgctggtg gtcaccgagg acgggtcgcg gctgctgcac ggcctgcccc acgaactggc
     4141 cgtcgcctga tggaactccg cctgctgcag gcgctggtcg ccgtcgcgga cgaactccac
     4201 ttcggccgtg ccgcccggcg cctcggcatc gcgcagccgc cgctcagcca gcgcatccgg
     4261 cgcctcgaac acgagctgga cgtcaggttg ttcgagcgga acaggcaagg ggtgtcgctg
     4321 accacggcgg gcgcggagct cgcggagcag gccaggcgag tcatcgccgg cgcggagcac
     4381 gtggagaagc tggcgtacaa catccgcagc ggcggagcgg ggaccctgcg agtcggcgct
     4441 gtcggctccg ccttctacca ggcgctgccc gccctgctgg cacccgcgcg cgagcggctt
     4501 cccgaactga gcctgcacat aagggagatg gagaccccgc agctcatcac cgcgctgctc
     4561 tcggcggaac tggacgtggc cctactgcgg ccgcccgcgg gccgggggct gcggtcgcgg
     4621 accgtctggc gtgagccgct ggtcctcgca ctgccggagg ggcatcccct cgccggtgag
     4681 ccggaggtgc acacccggct gctcgacggc gagcccctgg tgctcttccc ccgcgactcg
     4741 ggccccggct actgggaccg cgtcgagacg ctgctgcggg ccgcggacat cgcgctggaa
     4801 cccgtcgccg aggcggacca cgtgaccacc atgctcggac tcgtcgcgct cggagtgggg
     4861 ctgagcatcg tccccgcctc cgcccgggtg ctgcgtctga ccggtgtgcg gtacgtcccg
     4921 ctccagcccc ggacggagtt gccgctggcc gccgtcgtca acccggagac gctcaccccg
     4981 gccgtggacc gcttcctcac cacgctgccc aggaagcccg tcctcgccgg cgaccccgaa
     5041 tgacgggcgc tcctgcggtc gtgaccgccg gcggcagcga gcagcatgca gcgcgggacg
     5101 ggcgcgacca cagcgcatgg acgacgacag gcaactaccg tccgctgccc cgtagtcgtc
     5161 gcccgcgccg agggaacccg ggccaccggg ggggggtaga gggcggcgcc ggctcagcct
     5221 cccacctcgg tcccccacca gggctaagct ggcgcgatgt tcacaccgca aggcccgagc
     5281 cttcgcgaac tcgcccgtca ggcactctcc tccgtcgagc acggctacga cctcctcgcg
     5341 ccgaagttcg accacacgcc cttccgcacc cccgactcgc tcctctgcgc ggtgcggcgg
     5401 gcgctcgcgg agatcggccc gttcgagcac gggctggacc tgtgctgcgg caccggagca
     5461 ggtatgaccg tgctgcgcga ggtgtgccgg aggagcgtca ccggagtgga tttcagcgcc
     5521 gggatgctgg aggcgggcag ggagcgagcc gctctccccc acccgtctcc cggcgacgcc
     5581 cggggcgccg gggcacccgc cgtctcatgg gtgcgcggcg acgtccacgc gctgcccttc
     5641 aagcccgtct tcgacctggt cgtcagcttc ggcgcgttcg ggcacttcct gccgcacgag
     5701 ctggacggtg tgttcgccca ggcccactcg gttctccggc ccggcgggcg cttcgcgttc
     5761 ccgcttcctg cccccgcgac gccccgctcc tcctggtact gggcggcact gggcttcgac
     5821 gcggcgatgc gcgtccggaa cgccctctgg cggccgccgt tcgtcatgta ctaccggccg
     5881 ttccggctgg gcctggcccg gcggaagctg gagcaggcgg ggttcacggt ggagctgtgc
     5941 gccctgcccg agttcggccg tcgggccgac ggaagcccgc ggtgccggat ggtcgtggcg
     6001 acgcggacgt agccgacggt ggcgacgctg aaggagccgg cgggggccgg ccgtcggccc
     6061 gccccgcgtg accggcccgc gcgggctgcc cgcgcggatg ggcggcggcc cgactggccc
     6121 gactccccgc ccggaggcgg cagttcagcg gcgaccggac ggcgcgcccc tggcagccga
     6181 gtacgcgaca ctggtgccat ggacggtgac cgcgaagcgg acgcgaacag gctggcggcg
     6241 gaatcggccg cccggaacga ccccacgggg tggttcgaga agctctacgc ccaggccgcg
     6301 gcgggtgagg ccgtcgtgcc gtggaaccgg gacgcgccca accccctcct cgtcggctgg
     6361 gcggagcagt ccggagtcgc gggcgcgggc cggcgggcgc tcgtcgtggg ctgcgggctg
     6421 ggacaggacg ccgagtacac cgcgaggctc gggttccgca cgaccgcgtt cgacatctcg
     6481 cccaccgccg tgcgccaggc gcgggagagc ttccccggct cggccgtcga ctacgtcgtg
     6541 gccgacctcc tcgacccgcc cggggagtgg gcgggcgcct tcgacctcgt cgtcgagtcc
     6601 gtcacggtgc agtccatgcc gctttcggta cgggcgcggg cgatcggcaa cgtggccaag
     6661 atggtcgccg agggcgggga gctcctggtg atcgccggcg cccgcgagga gggcgagcag
     6721 gtggacggcc cgccgtggcc gctcacccgc acggaagtgg actccttcgc cgtccgcggg
     6781 ctccacaccg cctgggtcga gcgggtggcc catccggacg ccttcgagca gcgccactgg
     6841 cgcgcccggt tcctgcgcac cacctgaccc ggcgacgcgg gcagacctgc gccggatgca
     6901 ccccgcagtt cactgagggt gcggccgcag cgcgtggtcg gcggtgcagc gcggcggctc
     6961 cagccggtcg gcaagacgcc tcaacgcgcg ggcgagagtg tgccgggacc ggccgggcgg
     7021 gcgcggctcc tccgggatct gcggcgcgtc cggcagcgcg gacccggcgt gccgcctggt
     7081 gacctccacg atcatgggac ctgctacggg gaacatggcg tctcctccgg ttcgtcggtt
     7141 cgggtgcgtt cggttcgggt gcgttcggta cgaatgccgc tgtactggcg gagcgttcgc
     7201 tgttctgggc ggcgttcagg acggctgttc agggcagggg ccgggcggtg ttcagcgggg
     7261 cgcgggaccg gtcgtggcac gcacgacgag ttcggtgggc agctggacgc gcggaacggc
     7321 ctcgcccgga tcccgcggtt cgagaaggag ccgtgcggcg cggcgcccct tctcccccat
     7381 cggctggcgg accgtcgtca ggcgggcacg ggccgcttcg ggcacgtcgt cgaagcccgc
     7441 gaccgagatg tcccggccgg ggacgagacc ccgctgctcg caggcgtcga gcacgcccag
     7501 cgcgaggacg tcaccggtcg ccagtacggc tgtcggcctg tcggcgacgt cgaggacgtg
     7561 cgcggccgcg gcggcagcgg cggggcgtga gttgcggccc gccgccacga cggggacgtc
     7621 cgcccagtcg acgcccgcct cctccagcac ctcgcggtat ccggccagac ggccgtggag
     7681 tacggcgcac tcggagaccc gctgctcctc gacggtggcg ggcccggcgt ggcccggttc
     7741 gacgacgtgg tcgaccatca cggcgacgcg ccggtggccc agcctggcga ggtgctcggc
     7801 cgccagccgc gccgaggcgc gctcgtcgat gcccacgtgc gggatcgacg ggtcgtcgtt
     7861 ctcgtcggtg gtgaccacgg ggaggccgcg cgcctggatc accttcttcg ccgggtgccg
     7921 cacgggcatg cagtacaggc agaagccgtc caccacggcg tcgcgcatcg ccgtctccgc
     7981 ctcgtcggtc ccgggcggca tcgggatcag cagcaggccg gtgccggacg actcggcgac
     8041 ctcggccact ccccggagga agccgacgga gtacgggtcc gcgaacgcgt aggagagggt
     8101 ctcggtgaag accaggccga tcgcccccgc cctgccccgc cgcagcgagc gggccgccgc
     8161 gtcagggccg gggtagccga gccggcgggc ggcctcgagg atccgctcgc gcagcgcgct
     8221 gttgagctgg tcgggacggc tgtaggcgtt ggagacggtc gtgcgtgaga cgcccacctc
     8281 gtccgccacc gtctgcagcg tcgctcgcgt ggtccggggc tccatggctt gctcgcctgc
     8341 cttctgtatc gatcaagtct gtatcgatac agtagaaagc gcggcgtgcg tctgtccact
     8401 ccttttccgt cgctctcagc gggctacgcc cgcagcagac cggcgcaccg gcccgcgctc
     8461 agggctgcct gcgcgcctgc tcgccggcct gcgaggcggc ctcacgctcg gagctcgcgc
     8521 tgctggtgct cagcgcgccg ccggcgctct ccaggtgcgc gcgcacgaac cactggtaga
     8581 gctccaggcc ccgaagctgc tcgatgagca tgtcctgggt gacgggatcg ctctcggcgg
     8641 tcgccctgac ggccgcgcgg tggtcctcga tgatccccgt gtagacgagg tccagggcac
     8701 cgagatgctc gatggactcc gccctgccga tcgtgtagtc ctcccagtgc ctgccctcca
     8761 cgatcgcccc gggggtgccg tgcggcgagc cgccgagcgt cgagatgcgt tcggcggtcg
     8821 tgtcggtcat gtcgcgcacc gagtcgacct gcgggtcgag catctcgtgc accgcgatga
     8881 agtgcgggcc gaccacgttc cagtggatgt gcttcaacgt cagggcgagg tcgttgaggg
     8941 cgtgcaggcg cgtcttgagc aactggatga cgtcgccgcc gtcctgctgg ctcatgccgg
     9001 ggacggtgta cttcgggttg ggggcgctgc tggacacggc tgtctccctc tccacgtcga
     9061 ctgtccgccc gcgcggcggg ccacatccat gccaccaccg tgtgccgcgc ggcgcctgcc
     9121 ggggcgcacg cccgtacccc attcgggacg caggcggtcc gtgcggtgcg cgccgcggcg
     9181 tcgtacgccc cggtacgtcc gggcggcggc gagggtgtgg tcatgactgt gctccacgac
     9241 agcggcctga cccgcgcgtt cgacagggcc gcgggggcgt acgaccccct gaccgcgctg
     9301 aaccccggct accaccgcca cctgcggcgc gcggccgagc ggatgctgac cggcgaccag
     9361 cgcgcccgcg gcggcgacgg catgcgcgtc ctcgatctgg ggtgcggtac gggcgcctcc
     9421 acggcggcgg tgctccgggc ggcgccgaag gcccggatcg tggcggccga cgcgtcggcg
     9481 gggatgctgg agcgggccgg ggccaaggcg tggcagggcg acgtcacctt cgtgcgggct
     9541 ccggcggagg ggctggagga ggcgggggtg cgggggccgt tcgacgcggt cttcgccgcc
     9601 tacctggtcc gcaacctgag cgaaccggac gccgtgctcc gggacctgcg gcggatgctg
     9661 ggtccgggcg ggcggctggc cgtccacgag tacaccctca gcggcgccgc ggtgcaccgg
     9721 gcggtgtggt ccgcggtgtg ccggggcgtc atcgtgccgc tcggatcgct cggcccggga
     9781 ggcgggcggc tgtaccggca cctgtggcgc agcgtcctcg cgttcgacac ggccggagcc
     9841 ttcgccctcc gcctccggtc ggccggtttc gagtcggtgc gctgcgacgc tgtgcgtgga
     9901 tggcagagag gcatcgtcca caccttccac gcgacggtgc cggctgcctc ccgggaggct
     9961 gccgcggagg aagcgggtac cggcgggcga ccgtgaccgg ttagccggcg gggcgcttct
    10021 ccacgacgcg gcgcacgagc gcggggagcc gctcgtgcgc cggggcccgc agacgggcct
    10081 gttcgaggac cgtcagggcg tccgcggtga gctgttcgat gcgcgcctcg acggcgtcgg
    10141 cggcgccgag gcgggtgagg agatcgcgga cccgccggag gtcctcgggg gacaggtccc
    10201 tgttgccgat ggcgtcgcgc agttggcgct cggcctcgtg tctgctgtgg gcgcgggcac
    10261 gctgcagggc gatggccgtc agatacgtcg aggcgccgtc cttgatgtcg tcgcccgacg
    10321 gttccccgga gccgtcgctg ccgaacacgc cgacgaggtc gttgcgcagc tggaaggcga
    10381 cgccggcgct gcgtcccgcc ctgcgcaggg acgcgatcag gtcgggaccg gctcccgcga
    10441 tggccgcgcc caggtggagg gggcgctcga cggtgtagag gccgctcttg agataggcca
    10501 cgcgcagcga ctcctcgggc gagtccacgc cggtgctctg cccgtacagg tcgaggtact
    10561 ggccggcgat gatctcggtg cgcatggcct gccaggccgg ggccgccgcc ctgcgggcct
    10621 tggcgtccag gccggcgctc tcgaagaggt cgtgggccca caccagggcg aggtccccgg
    10681 cgagcacggc ggcgtacgcg ccgaagtcgt cggggtcgcc gcgcagtccg gcggcgcggt
    10741 gccggtcggc gaaggcgacg tgggcggcgg gcgccccgcg ccgcgagggc gagccgtcca
    10801 tcaggtcgtc gtggatcacc gcgcaggcct gcagcagctc cagcgcggtc gccaccttca
    10861 gcacggcctc ggcgttcgcg ccgcgggact ccccgccgca gcctcgccag ccccaccaca
    10921 ggaacgcggg ccgggtgcgc ttgccgccgc ggaggacgac gtcgacgagc acgtcgatga
    10981 cgtcccgcgc gaactgctcg ctgctgcggg cggcctcttc gcggcgctgg gcgaggtacc
    11041 gctcgaggag ggtgccgatg acggcggcgg tgtcctggtc gggatcggcg cccagggcgt
    11101 ggggcggggc gtcgtggctc gcctcgtgca cgtgtgcgct cggtcggcgc tgcacggcga
    11161 ctccttcctg agaggtcggc ccggcagagc acaccgagtg cggtcacgga cggcgcagaa
    11221 gggtctccgg agagtttttc agcagccgcc gggtcgtgca cctcggccgc caccagcagc
    11281 gggacgcgcc gcaggcattc accggagatg ggagggcact cgggggtcga aatgcgcaaa
    11341 gcgcctgaaa ggcacatgta catgtcgatg agtaggaaga tggacagggg tggccggcgc
    11401 tcctggagga tccacggaag cgccgctgtc gggagggtcc gccgcaagat ggcggagagt
    11461 acccgcgcgg tcagcggccc agagggttcc ggcaccgtcc ggccggggcg gagggaggcg
    11521 ctccgggcgc gggagaccgc cggcagcgcc acccacgacg cagcggacct tcacgaggga
    11581 ggtgggcgca gctcatgagc gacacggaac agcgcaccca gcgggaacag ctcttcacgg
    11641 acttcgagaa aagcgtcaac atgccggccg gacagctgga gcgctggctc gccaccagcg
    11701 aatcccgcaa cgtcggacgg cacaagggcc agagcgagag ccacgggcac gcggcgggcc
    11761 gccgtatcgt gcggctgctg cgcacgcgca gagccgactt caccgcggac gatctcgtgc
    11821 acatgcgcag agcggtccgc cacatagagc ggcagctgcg gcaccggccg cgcggcgacg
    11881 tcagcgacac ggcctggcgt ttctccctga tgaactgggg ccacgacccg cagcgccatg
    11941 accaggcgcg ctgatccgct ccgcctccgg cggggccgcc gcgcaccggg cggggccggg
    12001 cgaggatgga accatgctgc tggctgaggt cgcccgtacg tcgcaggaga tcacgacggt
    12061 ctcctcccgc aaggagaagg tggggatcct cgcgcggatg ttccgccgcg cctccccgga
    12121 ggaagtgccc ctggtggtca cgtacttggc ggggagactg ccgcaacgca ggacgggcgt
    12181 gggattcagc gcgctctccg ggcgccatcc tcccgctgct gccgcgcagt tgaccgtcgc
    12241 ggcggtggac ggggcgctga cggagatcgc cgccgtccgc ggcaagggcg cccagacgga
    12301 acgcgcacgg ctgctggcgg cgctgatgtc ggcggccacc gaggaggagc agcacttcct
    12361 cttccggttg ctgacgggcg agttgaggca gggcgcgctg gacgcgttcg ccgtggaggg
    12421 cctggcggag gcggtgggcg cacccccggc cagggtgcgg cgcgcggtga tgttcggcgg
    12481 ctccctcggc gccgtcgcac gggcgctgct ggaggacggg ccctccgcgc tgggccggtt
    12541 cgagcttcag acgggccgcc cggtgctgcc gatgctggcg cagagcgcga agaacgtgct
    12601 ggaggcgctg acgaagctcg gcccgtccgt ggtggaggag aagctggacg gcatccgggt
    12661 gcaggtgcac aaggacggcg acagcatcgc gctctacacc cgcacgttgg acgacatcac
    12721 cgaccggctg cccgaagtcg tcgccgccgc cggggacttg gcggcgcgcc aggccgtact
    12781 cgacggcgag gtgatcgctc tcgacggcca cgggcgcccg cggccgttcc aggagacttc
    12841 ccagcgggtg ggctcccagc tggacgtggc gacggcgcgc acgacactgc cggtcactcc
    12901 gcggttcttc gacgtgctgt cggtggacgg ccgcgacgtg gtggatctga ccgtgcggga
    12961 gcggcacgcg gcactcgcca gggtggtgcc cgaggagctg cgcgtgcgcc gtctcgtcct
    13021 ggaggatccc ggaagcgccg aacagcgcgc cgcggcagag gagttcgccc gcgaggtgct
    13081 ggagcagggc caggagggcg tcatggtcaa ggctctggac tcgtcctaca gcgcggggcg
    13141 gcgcggcgcg gcatggctga aggtgaagcc ggtgcacacc ctcgatctgg tggtgctcgc
    13201 ggcggagtgg ggccacgggc ggcgtacggg catgctgtcg aacctgcacc tgggggcccg
    13261 gcgccccgac gggagcttcg ccatgctcgg caagacgttc aaggggctca ccgacaagct
    13321 gctcgcgtgg cagacggagc agctgcgcgc gatcgccgtc gccgagcacc cgtggggcgt
    13381 ggaggtgcgg cccgaactgg tcgcggagat cgccgtcgac gggctgcagc gctccacccg
    13441 ctacccggcc ggcgtgacgc tgcgcttcgc gcgggtgctg cgctaccgca cggacaagac
    13501 cgccgccgag gccgacaccg tcgacgacgt cctcgcgctg cgcaggtagc ccgcagcgca
    13561 gcgcgaggtg ccgggacgtc gggacgtcgg gagggcaaca ggacgggacg gacggtgaag
    13621 ggtgaacggg ccgggcctcg cggcgtgttc agcctcgcgg caccaccttg gacaggacgg
    13681 agggcagctt cgcccagtcc gaggtgatga aactggcgtg cgaggcggcg agttgggtga
    13741 gcctgtcgcc ggcctcctct tcggtggggc tggtcccgtc gatctccggg gcgaccttgt
    13801 gggcgtcggt catcaccacg agatagccgt tctcccggta ccaggccgtg tcgatctcgc
    13861 cgccggtgaa ggtggaggcg tcaccgtcga agaggacgaa ccacgggcgc agcgcctcct
    13921 cgtagcgttc ggtgcgggga tcgcccttct cggcgccgtg caccgcgggg aaggcaccgg
    13981 cctcggcgag ggtgcccttg cctgcgaggt ccttgaggtg agtggcgtac tcctcgtcgg
    14041 tccacaggtc gtccgccggg ttgccctcct cgagggtgcc ggggatcagc tcgatgacga
    14101 acttgcccgc gagggcgtcc cggtcgggcc atccggaggc gcccacggcc tcgtccaggg
    14161 tggcgtggtc gccgaccacg tcggcggggc gcagcagggc gtcgcccagc ttctccccca
    14221 gcagggcgtc cagttcgtcg gggccccggt cggccttgtc gtagaagccg tccttcatct
    14281 cgaccttgat gagcacgggc gggtgtccgg ggttcgcgtc gtgccaggcg cgcatgtcgg
    14341 ccaggcagcc gtcgagtgcc tggtcgcgct tgttggagcg cagttccgcg gccgactcgg
    14401 cgttcccgca gttgttgtcg ttgcccgtgg ggttgctgtg ggagacccgc catcccttgc
    14461 cgacgatgtt ggtccacacg tcgagttcga ggagcgaggc accggagtcg agtgcgtcgg
    14521 cgaagtactc gtacttgtcc ttctcgtagg cgttgtgcac gccgaccgac gtggtctcgc
    14581 cgtaacttgc ggcggcggcc tcggggcctg cctgcgcgga gaggggcacg gccactgctg
    14641 cggctgccgt gacgagggcc gccgccgata cggcgacggc caggcggggt ctgctcatgg
    14701 ggctgatacc tcggtctgtg ggggccaagt gagcatcagc gtagagctgt tcgagcagcg
    14761 tggggcgggc ttggcagaac gggcagtacg gcggcgggcc ccgcagcgaa gcctcctgcc
    14821 gcccggaagg gtcggcagga ggcggctgcg gcttctccgt gcggcagggc ccgttcagcg
    14881 gcggcggcgc ttggagcggt cgagagcggc gacgccgagg gctgcgaggg ccagctgtat
    14941 gagccactcg atccagtcga cgctcttggt gtcacccaca ccgaagtagg tggcgatggc
    15001 cgatccgacc agcgcggcga cgatgcccac gccgatggtc agcaggatgc cgacgcgctg
    15061 ccgtccggga acgatcagcc gccccagtac accgatcaca gtaccgatca cgatggcgct
    15121 gatgatgcct gcgatctcca tgatcacccc ttgtccgtcg tggtgttccc ttctcttgcc
    15181 cgcatccgga cgccgcactc ggcgctcttt tcgaacggtg agtagggttc gggacggacc
    15241 gccgggagac gccgacgacg gcggtcccgc agcgcggtgc ggcaccccgg cgccgcaccg
    15301 ctgcccgtcc cccgcggagt ccctcacgga aggagccggc gatggacgcg ctgcttccgc
    15361 gccctccggt gaacctcggc cccggcgccg tgcacgttcc gggctggctc ggcatcgaac
    15421 agcagcggag ccttgtcgcg gcctgccggg agtgggcgtg cggaccggtg ccgctgcggc
    15481 acacgaagct gccgcggggc ggcgtgatgt ccgtccggac ggtgtgcctg ggctggcact
    15541 ggcagccgta ccgctattcc cggacggcgg acgacgtgaa cggccgccgc gtggccgaac
    15601 tgccggaatg gctggccgac ttggggcgcc gcgccgtggc cgccaccgcg gggcacgacg
    15661 acgcgcgcgg tgagggctgg acgtccgggc gctacgaccc ggacacggcc ctggtcaact
    15721 tctacgacgg ccgggcgaag atgggcatgc accaggacaa ggacgagcgg tccggcgccc
    15781 ccgtcgtctc gctgagcatc ggcgactcct gccgcttccg cttcggtaac accgcggggc
    15841 gcggccggcc ctggaccgac gtcgagctgg cgtcgggcga cctgttcgtc ttcggcggtc
    15901 cggcgcgcta cgcgtaccac ggcgtgacca gggtcttcga aggcaccggc gaccccgcga
    15961 cgggcctcgc ccccgggcgc ctcaacctga cgctgcgggt caccggcctg agcggctgac
    16021 gccgcctgtt gcggggcgcg tgccgtacct cgccctccgc atgtgtaaga ccgcccgtac
    16081 gtgcctaccc gtagcccatg gacgagaagt accccgaccc ggacgagccg ggccacactc
    16141 cgggactcga acccggcggg caggtaccgc ccggcgagac cccgccgggt gaggacagca
    16201 cggccggggc cgggccggac gagcgccaca accctccgaa gggatgggcc aaggcaccgg
    16261 tgatcatcat cggcgtgctc gtcctgcttt tcctcatcta cttcgtggcc tgggcggtcg
    16321 agctgtgaac cgcccggacc ggcgcaccgg cggcgggcag gactcgtgac ggtggcctga
    16381 ccgcccgccg ggcaccgccg gggccgcggg tacgcaagcg catcccttcc cgcttccgta
    16441 cccgcggccc cggcgttttc acgtcggctt cgtcggcggc gtcggcttcg tcagcggtgt
    16501 cggcgcggcg tcggcggcgt ctccgccccc gcatctccgc gccacggcgt cagcgccggg
    16561 ggccgcttct gagccgcccg gctgtgccct ggcggctgcg ggccggaggg cggctcacgg
    16621 cggcggagcc ggctgcggct cgggctccgg aggcaccggc tcggggccgg gcgacggggg
    16681 ctgcgggatc gggtcgggtg ccggaccggg cggcggagcc ggtgtcggcc ccggaacggg
    16741 atcgggggcg ggacccggcg gcggcgtggg tttcggcgga accgggtcgg gccgccggcc
    16801 cgtggcggcg tcgtatgact gctgcggcat ggaaactcca gcggtctcgc atagcggcat
    16861 gtccgtaccc gcgccgggtg cccgttcccc gggggtgcca ctctccccgt ccccgggccg
    16921 ccggcggagg cccggggacg ggagaggcag ccgcaacgag cggtacgggc cgcgcggggg
    16981 tcagtccgag ggcacctcgc tgcggtcgcc gccccagagg gtgtggaagg agccgtcgcg
    17041 gtccgtacgg cggtaggtgt gcgcaccgaa gaagtcccgc tgggcctggg tcagggacgc
    17101 ggggagccgc tcgctgcgaa gggcgtcgta cgacgcgaga gcggcagaga agccgggcac
    17161 cgggacgccg tgctcgaccg cggtcgccac caccgagcgc cagtctccct gggcctcgcc
    17221 gatctccttg ccgaagtgat cgtcggcgag cagcgtcggc aggtccggac gggcggcaaa
    17281 tgcggagcgg atgcggtcca ggaacgcggc ccggatgatg cagcccgcgc gccagatggc
    17341 cccgaccgcg ccggggtcga taccccagcc gaactcctcg ctgccgctgc ggatcatgtt
    17401 ccagccctgc gcgtacgacg tgatcttcga ggcgtacaag gcctgctcca ccttctccgc
    17461 gaagcgctcg gcctcctccg gcgcgagggc cgaggccgcc gggccgggca ggtgcccgct
    17521 cgccgagcgc aggtcggtgt ggcccgagag ggagcgggcg aagacggcct cggcgatgcc
    17581 cgagaccggc actcccaggt cgagcgccgt ctgcacggtc cagcggccgg tgcccttctg
    17641 ctcagcctgg tcggcgacga cgtcgacgaa gggcttgccg gtctccgcgt cggtgtggga
    17701 aagaacctcc gccgtgatct cgatgaggta cgagtccagg cgtccggtgt tccactgccg
    17761 gaaggtctcg gccacgcgtg cggggctgaa cccggcgacg tcccgcagca ggtggtaggc
    17821 ctcgccgatg agctgcatgt cggcgtactc gatgccgttg tgcaccatct tcacgaagtg
    17881 gcccgcgccg tcggggccga cgtgcgtcgt gcagggggtg ccgtcctcgg ccttggcggc
    17941 gacgctctcc agcatgggac gcagcgactc gtacgcctcg gccgagccgc ccggcatgat
    18001 gctcgggccg tgcagcgctc cctcctcgcc cccggagatg cccgcgccga cgaagtgcag
    18061 gccccgctcg cgcaggtcgg cttcgcggcg gcgggtgtcg gcgtagtggg cgttgccccc
    18121 gtcgatgatg acgtcgccgg gttcgagcag cgcggcgaac tcgtcgatca cggcgtccgt
    18181 gggcgccccg gccttgacca tgatgatgag gcggcgcggc cgctccagcg cggcgacgaa
    18241 ctcctccgcc gtctcggcgg cgacgaagct cccctcgtcc ccgaagtcac gcaccaggtc
    18301 gcgggtcctg gccgccgtgc ggttgtgcac cgcgaccgtg tacccgttgc gggcgaagtt
    18361 ccgggcgagg ttgcggccca tcacggcgag gccggtgacg ccgatgtgtg cggtggtgct
    18421 catgcggatg ctcccggggt ggactggtcc ggagtacgga acgcgtttcg gcggtggcaa
    18481 ttctgcccgc cgtcagagtg tgcgcggcgg gaggggcagg ggcaggccgg ggagaccgtc
    18541 gaggctcacc ccgacgtgct ccttcttctc gcagtaggcg gcgaaggagt cggcggtctc
    18601 gcgggcgaac cgctgcgtgt gcagggggcg ctccccctgg tgctccatga acggcaccgc
    18661 gaagccgcat gtgtcgctga tcctctcggc ctcgaccgtg atgacggccc gcaggtccgt
    18721 gcgggcccgc atctcctccc cgaagtgcgg cagcagccgc gcccagcgcg ggtcgtcgcg
    18781 gaagacaggg gtgccgcgtc cgtggatgcg caggatccgg ggcgggccct cgaacgcgca
    18841 ccacatgatc gtcacgcgcc cgttctcccg caggtgcgcg acggtctccg cgccgctgcc
    18901 gccgagatcg aggtaggcga cggtgcggtc gtcgaggacc gcgaaggatc ccgcgagccc
    18961 cttcggtgag aggttgacgt ggccgtcggc tgcgagcgga gcggtggcga cgaagaagac
    19021 gtgctgcttc tcgatgaagg cgcgcacccc gtcgtcgatg tgttcgtaga cctgacccat
    19081 ccccgcatta tcggcccgcc gggcgccccg ccggacccgg atcggccaac ggcccggatc
    19141 gtccgacggc gggacgggcc cgcgccggac ggcggcgcgc ccgccccacg tcccgccggt
    19201 tccggggctc aggccagcgg ctcgccgtcg acgaacgtct gcacgccgtc ggcgaggaag
    19261 cacagatgcc gtgcgacgcg ccgggcctcg tccagcggct tctcgtagca ccaggcggcg
    19321 tcctcgatgg cggtggcgcc gtcgcgcacc gtcaggtagg aggcctggcc cttgtacggg
    19381 cagtgcgtgc gcgtggcgct ccgttcgagc agttcaccgc ggacgtcgct ctgcgggagg
    19441 tagtagcggt tgggcagccc ggtctccgac agcagcatgg cgcgcttgct ctccgcgacc
    19501 tggcgtccgg cggcctcgac caccacgtgc cggctggtgg gccgtacgtc gacccggtgg
    19561 tacgggtcgc ggatgtggcc gacggcctcc tcgtcctcgt cgaaccaggt gtccatcgac
    19621 gcccagtaca cggcgacgtg gccgcggagc cactctgcgc cgggcagcgg ttcggggtag
    19681 ccccacacgg cgttctcggc cagccgctcc cccgcccgga cgctccagta gcgggcgtcg
    19741 cccttgaagg ggcagtgggt ggtgtggggg ctctcctcca gcagttccgg ccgtacgtcc
    19801 gaggccggga cgtacacctg cggcagcaga ttgctctcgt gcaggagctt ggcgttgtcg
    19861 ctctccagga cctcctcccc ggagagcagt gcccgtaccc ggcgcgggaa gggctgccac
    19921 agcagccggt gcgccgggcc gtcgatgctg tagttgacgg tggccggtgg ccgcgacgcg
    19981 agcggcccgc cgccgagggt gagtgacatg gcgtgacgac ctccgggcgt ggcggtgatg
    20041 tgcgctgcct gctctgctct ccactgtcgc accgccacgc cccgcggggc aggcgaaggg
    20101 atgcacgccc cgcggggcag gcgaagggat gcacgccccg cggggcaggc gaatctcgcg
    20161 gcggtgcgcg gctgcgcaca tgctgcgccg ggctggtgga atgctccggg catggacacc
    20221 gcgaagctcg aactggccgc ccggcgctgc cgcgaagcgg aagaggccct cgaagcggcc
    20281 cgcagcgacc tgcgtacgga agccgtcgtg gcactgcgcg gcgccgaccg cgacgggcag
    20341 gccgccgtct cccgtatcac cggctggtcc cgcgcctacc tcaggaagct gatgcgcgcc
    20401 gacagggccg gctgaccagg gccggccgag gctccccggc ggttccggcc ccggcggccg
    20461 cgccgcccgc cgccctcggt gcgctgcgga cgccttcagc tgaggtatgc gaggacggcc
    20521 agtacgcgcc ggtggccgct gtcctcgacg ggcagatcga gcttggcgaa gatgttcccg
    20581 acgtgcttgt gcacggcacg ctcggtgacc acgagccgcc gggcgatctc tccgttggcg
    20641 aacccctgtg ccatgaggcg cagcacctcg cgttcacggc cggtgagcgc cgtcagcgga
    20701 tcgtgccggg cgagcacctg ggagacgacc tccgggtcca tcgacgtacc gcccgcggcc
    20761 acgtgttcga gcgcccgcag gaactcctcc actctggcca cccggtcctt gagcatgtag
    20821 ccgatcccgc cggcgcggtc ggagagcagc tcgagggcgt aactcctctc cacgtactgg
    20881 gagaagacca gcagcggctg tcccggacgc tcgcggcgga tgcgcagcgc cgcgcgcagc
    20941 ccctcgtcgc ggaacgacgg cggcagccgc acgtcgacca cggcgacgtc gggccgctcg
    21001 ccgaggacgg cgtccacgag cgcctcgccg caggagacct gcgcgaggac ctcgtggccc
    21061 tcggcgcgca gcagcagggc cagcccttcg gccagcacga cgttgtcctc ggcgatcacg
    21121 acccgcacgg gatgtccaca gctacgcaag tcggg
//
