LOCUS       NZ_FMHJ01000007        20579 bp    DNA     linear   CON 28-JUL-2024
DEFINITION  Streptomyces sp. WMMB 714, whole genome shotgun sequence.
ACCESSION   NZ_FMHJ01000007
VERSION     NZ_FMHJ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. WMMB 714
  ORGANISM  Streptomyces sp. WMMB 714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900090125.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 02:17:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,656
            CDSs (total)                      :: 5,578
            Genes (coding)                    :: 5,496
            CDSs (with protein)               :: 5,496
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 4 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 15 of 82
            Pseudo Genes (incomplete)         :: 72 of 82
            Pseudo Genes (internal stop)      :: 4 of 82
            Pseudo Genes (multiple problems)  :: 8 of 82
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 64626
            Orig. end                         :: 85205
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMHJ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20579
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="1"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20579
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20579
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10579](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10579)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            complement(243..629)
                     /locus_tag="H181DRAFT_RS14475"
                     /old_locus_tag="H181DRAFT_02913"
     CDS             complement(243..629)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125141.1"
                     /locus_tag="H181DRAFT_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02913"
                     /product="VOC family protein"
                     /protein_id="WP_045864869.1"
                     /transl_table=11
                     /translation="MRIHLSSVFVDDQEEALRFYTDVLGFAKKNDVPLGAHRWLTVVSP
                     EDPDGTELLLEPDAHPAVKPYTSALAEDGIPAASFAVDDVRAEYDRLREAGVRFTQEPL
                     EMGPVTTAVLDDTCGNLIQLVHSA"
     gene            complement(626..919)
                     /locus_tag="H181DRAFT_RS14480"
                     /old_locus_tag="H181DRAFT_02914"
     CDS             complement(626..919)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640268.1"
                     /locus_tag="H181DRAFT_RS14480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02914"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_045865099.1"
                     /transl_table=11
                     /translation="MAEDVFKALADPTRRRILDELVERDGQTLFEICARLVSKHGIGLS
                     RQAIGQHVAVLESAGLVRSRRQGRYKFHDLDTEPLEHIAARWLRPDAPEGTP"
     gene            1093..1860
                     /locus_tag="H181DRAFT_RS14485"
                     /old_locus_tag="H181DRAFT_02915"
     CDS             1093..1860
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (4-246). E-value: 8.3e-74. Score:
                     239.9. Matches aSDomain:
                     nrpspksdomains_H181DRAFT_RS14485_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176252.1"
                     /locus_tag="H181DRAFT_RS14485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02915"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_045864870.1"
                     /transl_table=11
                     /translation="MTVNLEVAEGVGTIRLDRPPMNALDVATQDRLRELAEEASVREDV
                     RAVVIYGGEKVFAAGADIKEMQAMDHAAMVSRSKGLQDSFTAVARIPKPVVAAVTGYAL
                     GGGCELALCADIRIAGEGAKLGQPEILLGLIPGAGGTQRLSRLVGPSKAKDLIFTGRQV
                     KVPEALQMGLVDRVVPDEEVYDRAKEWAARLAAGPAIALRAAKESVDVGLETDIDTGLA
                     VERNWFAGLFATEDRATGMRSFVEEGPGKAKFR"
     aSDomain        1105..1830
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H181DRAFT_RS14485_ECH.1"
                     /evalue="8.30E-74"
                     /label="H181DRAFT_RS14485_ECH.1"
                     /locus_tag="H181DRAFT_RS14485"
                     /protein_end="246"
                     /protein_start="4"
                     /score="239.9"
                     /tool="antismash"
                     /translation="LEVAEGVGTIRLDRPPMNALDVATQDRLRELAEEASVREDVRAVV
                     IYGGEKVFAAGADIKEMQAMDHAAMVSRSKGLQDSFTAVARIPKPVVAAVTGYALGGGC
                     ELALCADIRIAGEGAKLGQPEILLGLIPGAGGTQRLSRLVGPSKAKDLIFTGRQVKVPE
                     ALQMGLVDRVVPDEEVYDRAKEWAARLAAGPAIALRAAKESVDVGLETDIDTGLAVERN
                     WFAGLFATEDRATGMRSFVE"
     gene            2240..2734
                     /locus_tag="H181DRAFT_RS14490"
                     /old_locus_tag="H181DRAFT_02916"
     CDS             2240..2734
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469882.1"
                     /locus_tag="H181DRAFT_RS14490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02916"
                     /product="ATP-binding protein"
                     /protein_id="WP_045865100.1"
                     /transl_table=11
                     /translation="MAGQGEVASVTERVPEVPGEPASDDSANSVLELVGDPTIAEVRLP
                     NRPESARCAREMARTVTESHWGLPGALVDDAVLLVSELVGNAVRHTGAHVFGLRMMRRR
                     DWIRVEVRDPSRGLPCLLPVHGLDTSGRGLFLVDTLCGRWGVDLLPRGKTTWFEMRITG
                     S"
     gene            2866..3402
                     /locus_tag="H181DRAFT_RS14495"
                     /old_locus_tag="H181DRAFT_02917"
     CDS             2866..3402
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS14495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_02917"
                     /product="hypothetical protein"
                     /protein_id="WP_052708588.1"
                     /transl_table=11
                     /translation="MTVRYRYARSKRPFLCTTLLTLALLTGCGGEAGGGSEGGKSADGA
                     GNASGGKDDSPGSGKAGPSPDAADGSDTDACRDAECEVVVRAGDVLRPKTSYGVQEFTV
                     ELINKGVVSWRTVFTTGSGAMQTRGSSVSSTSCTGGECNGRLGRTQGRLETDKLIIDFN
                     SIDDDSAVAKLTAKK"
     gene            complement(3350..3742)
                     /locus_tag="H181DRAFT_RS29935"
     CDS             complement(3350..3742)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024770.4"
                     /locus_tag="H181DRAFT_RS29935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_074467863.1"
                     /transl_table=11
                     /translation="MGNLTEPADQRPTAIVFGNGTVAVAGVSAARRLGPEVPRVSVIGY
                     DDLPPGEIVHPRLTTVGREAEQRGRSGAAGLLALLGGAGLRCGRTAPGRARVHGARSAG
                     LGRRRPGPGATSSPSASPLRCRRRSS"
     gene            3687..3941
                     /locus_tag="H181DRAFT_RS29940"
                     /old_locus_tag="H181DRAFT_02918"
     CDS             3687..3941
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS29940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_02918"
                     /product="hypothetical protein"
                     /protein_id="WP_045864871.1"
                     /transl_table=11
                     /translation="MPKTIAVGRWSAGSVRFPTASPPVLPVEPDGAEVVARDAHGRLHE
                     EPLTAEPRVTAGTLTGLDGLPPGTLELPPYGVVVAELTA"
     gene            4000..5241
                     /gene="manD"
                     /locus_tag="H181DRAFT_RS14510"
                     /old_locus_tag="H181DRAFT_02919"
     CDS             4000..5241
                     /EC_number="4.2.1.8"
                     /GO_function="GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="manD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007456337.1"
                     /locus_tag="H181DRAFT_RS14510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02919"
                     /product="D-mannonate dehydratase ManD"
                     /protein_id="WP_045864872.1"
                     /transl_table=11
                     /translation="MKIESAETVVTSPGRNFVTLRLVTADGVTGLGDATLNGRELAVAS
                     YLRDHVAPLLIGRDARNIEDTWQYLYRGAYWRRGPVTMAAIAAVDTALWDIKAKAAGMP
                     LYQLLGGASRRGALAYGHASGRDVPELLDSVRAHLADGYRAIRVQTGIPGLDSVYGVAS
                     SAAGSGERYDYEPARRATGGPVLPVEETWDTRAYLRHVPSVFEAVREEFGPELPLLHDG
                     HHRMTPIQAAKLGKSLEPYDLFWLEDATPGEDQAALRLIRQHTTTPLAIGEVFNSVHDY
                     TTLLAERLIDYVRSAVTHTGGVTAMKKLLDMAAVHGIRSGMHGPTDISPVGMAAQLHLD
                     LAVHNFGIQEYMRHSPHSLEVFRTSYTFEDGLLHPSDTPGLGVELDLDAAGRFPYEPAY
                     LPVNRLADGTVHDW"
     gene            complement(5279..6571)
                     /locus_tag="H181DRAFT_RS14515"
                     /old_locus_tag="H181DRAFT_02920"
     CDS             complement(5279..6571)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545791.1"
                     /locus_tag="H181DRAFT_RS14515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02920"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_254666857.1"
                     /transl_table=11
                     /translation="MLTACGLDEGPPDERVVRVLMVDNPQMQELEKLTARYFTKRTGIE
                     VDFTPLPENEVRKHIHDDFSAQSGRYDVATVSNFETETYADRGWLKPLDPYIAEDRAFD
                     QSDILLPLQLSLSGGDGKVYAEPFYGESSFLMYRKDVFEQLGLEMPARPTWKDVAELAE
                     KADRPEKGMTGICLRGLPGWGEMTAPFTTVVNTFGGTWFDKRWNARLTSPAFRRAAEFY
                     VGLVRESGEPDPSRTGYADCLRNMKRGKSAMWYDATAGAGSLEAGTSPVKGKMGYVPAP
                     VEKTRSSGWLYTWAWGIQKSSEKPGDAWKFISWASGKEYEALVGREFGWANVPAGKRSS
                     TYDRPQYRKAADAFAEVTEEAIGDADPRSPGVQERPAPGIQFVGVPEFTALGDKVSEEL
                     SAAIAGDQTVDDALRKGQREAEKVGAGYRKR"
     gene            complement(7032..7745)
                     /locus_tag="H181DRAFT_RS14520"
                     /old_locus_tag="H181DRAFT_02921"
     CDS             complement(7032..7745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954332.1"
                     /locus_tag="H181DRAFT_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02921"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_254666843.1"
                     /transl_table=11
                     /translation="MSLTSETGTMLREFLRSPIDTGAVAPSSRRLAEAVTAPVPERGDP
                     VVVELGPGTGAFTGTIQEQLRGRGRHLAIEINPQLAGRLSDRFPGVEVLNAQAAQLPQL
                     LAEQGHERADVVVSGLPWASFPRTVQSETLSAISRVLAPEGAFTTFGYLHARRLAPALR
                     FRRMLHEAFEEVVAGRTVWGNLPPALVYHGRRARKAAPLLGAASGGRSPVGLAPLPRRP
                     AVPGRSVGPRTPSAG"
     gene            complement(8053..>8360)
                     /locus_tag="H181DRAFT_RS14525"
                     /old_locus_tag="H181DRAFT_02922"
                     /pseudo=""
     CDS             complement(8053..>8360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031866.1"
                     /locus_tag="H181DRAFT_RS14525"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="H181DRAFT_02922"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LLLRRWRKLLGRTMGASPAGGAAGTAVRCSASARARPPAPPFRPA
                     GTS"
     gene            complement(8507..9613)
                     /locus_tag="H181DRAFT_RS14530"
                     /old_locus_tag="H181DRAFT_02923"
     CDS             complement(8507..9613)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471116.1"
                     /locus_tag="H181DRAFT_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02923"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_045864874.1"
                     /transl_table=11
                     /translation="MALRFVDLRRSPRAAVLLPVALLITIVVVDVLAPPHIHLGPLLVA
                     APAITPAFGGARLTAFVAVLAVAAQAVIAVLRDDRQLFSANHQAQIVALVVVGASLVLF
                     CLLRERRNRELRQVRHVSETAQRLILRPLPKRIGPLRVASLYLGAEAEARIGGDVYAVE
                     RTDSSTRLLIGDARGKGMPLAGEAALLLDAFHLAGHRQAPLDALAAHLNSSVTWSLADG
                     AESDEPGESFITAAIVEIPDEDDTVRMVDCGHPPPILVRDGRVSTVEAPRPAPPMGLGE
                     LSAAHFHVEEFTLGAGDRLLLYTDGVTEARDPEGVFYPLAARMESWTDCHVEALLHHLK
                     RDLLAHTGGRLGDDAALVAVERQRTSAQ"
     gene            complement(10001..10579)
                     /locus_tag="H181DRAFT_RS14535"
                     /old_locus_tag="H181DRAFT_02924"
     CDS             complement(10001..10579)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_02924"
                     /product="hypothetical protein"
                     /protein_id="WP_045864875.1"
                     /sec_met_domain="cypI (E-value: 2.7e-34, bitscore: 112.8,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAATLRDAVRGPGAGWRLAGAALIATTVAAQHPHQLFNRIRTR
                     DPLSVVPNWRFFAPHPAIHDSHLLYRTLSADDETSDWTQLSLTPDRTVQHAIWFPDRRL
                     GKAIFDVGDEILRNLPEGFPVVTKLPSYRTLVNYLRREIRESAEGTRAKGFQFAFARST
                     GYDMSEEPEMMFISPYTPMDPVPSHVRAG"
     gene            complement(10576..12498)
                     /locus_tag="H181DRAFT_RS14540"
                     /old_locus_tag="H181DRAFT_02925"
     CDS             complement(10576..12498)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435953.1"
                     /locus_tag="H181DRAFT_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02925"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_045865103.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.2e-10, bitscore:
                     34.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRNTGPLRRLARTVLKPPSLSRDRAIGISERLGALTTLNSSLEY
                     LTQRKQTDAGGMNDWEILRDAQRGRSPLLRKVLDGVSDRRVTTAVHASRAAVAAALLMP
                     GNQRWRGAANLYLSATGMLSYPRHLYGTDGTDQVSLTVQGATGAARLVRSEEAKDALIW
                     YVAVQSNLSYAVSGWVKLFGKSWRDGSALPGVMRTRTYGHRGMWSWTQKHPTAAKYLTH
                     SVLALECGFPVLYAFGGRLARPVLGSAVLFHGANAYLMGLGRFLTAFPSMHPLVAYTAV
                     PRTHPSGAKRDDRMLPVVAAALAAAAGKAVVTAVQRRSRVLEGPPDCRTHTASSGNRLQ
                     YRVHAQGDAGKPVVVFETGLAATPEHFSWMTGHLGSGTGLGLVSYARAGYAGSVREAAG
                     AYRIQESVEDLVDLVGATVGAGRKVILAGHSLGGEIARRAAPLLGDRLEGVVYLDSSHP
                     DELNRSPQQSESSPRLRELFTQMTWYLRSGSGALLSRPDWVDDLPVHTRERAFAQYCDS
                     RLWSAAAREWNAVEAEFSEFSGGLPPAPGRGLVVSAQATVDRDAEQLLMHDELAKSHQG
                     GASSVVIEGATHDGLLSSAEYAIRAASAIAAFAAGSGTSAGSAGSASEQEQDGQEQDEQ
                     ERASK"
     gene            complement(12814..12966)
                     /locus_tag="H181DRAFT_RS29450"
                     /old_locus_tag="H181DRAFT_02926"
     CDS             complement(12814..12966)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS29450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_02926"
                     /product="hypothetical protein"
                     /protein_id="WP_158715439.1"
                     /transl_table=11
                     /translation="MREIIVKAEPKLSESDKGQVVVPQGPVLATPVAAATVAFATGVAV
                     TKAVG"
     misc_feature    complement(13122..13137)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     misc_feature    13285..13300
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            13882..14490
                     /locus_tag="H181DRAFT_RS14545"
                     /old_locus_tag="H181DRAFT_02927"
     CDS             13882..14490
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018529555.1"
                     /locus_tag="H181DRAFT_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02927"
                     /product="response regulator transcription factor"
                     /protein_id="WP_045864876.1"
                     /transl_table=11
                     /translation="MAIRVLLADDEKLILGALSALLSLENDIEVVAEADNGTTALELAG
                     TRSPDVCVLDLHMPGKDGITVTRDLQSAVPAPRCMVLTSHAAPGYLKSALKAGARGFVP
                     KTTSAQRLADIIRDVHRGSQYVDPDMAADALSSGDSPLTRREADILTLAADGAPIGEIA
                     QRAALRPGTVRNYLSDIMGKLEVANRHEAVHAARRFGWI"
     gene            complement(14565..15032)
                     /locus_tag="H181DRAFT_RS14550"
                     /old_locus_tag="H181DRAFT_02928"
     CDS             complement(14565..15032)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_02928"
                     /product="hypothetical protein"
                     /protein_id="WP_045864877.1"
                     /transl_table=11
                     /translation="MTQWNRPDQPPHHPHRRKKSGKGKILGFGCLGLIAVIALVVVITF
                     VAMGGEESGGPAPDETSATPTERSPEPTAEDTAKSYGDGDYTVGRDIPAGTYESAGAKD
                     DVVEGCLITTEPKGDKMPQAKTADRNERIIITLSAGDGTLTVQGCEPLRRR"
     gene            15339..15809
                     /locus_tag="H181DRAFT_RS14555"
                     /old_locus_tag="H181DRAFT_02929"
     CDS             15339..15809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472717.1"
                     /locus_tag="H181DRAFT_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02929"
                     /product="DIP1984 family protein"
                     /protein_id="WP_045865104.1"
                     /transl_table=11
                     /translation="MKLAEALAERADATRRVEQLRTRAVSSARYQEGETPPEDSARLLA
                     EANDVLDTLESLIRRINRTNATVLIGEDGTITDALARRDVLRLRHSVITAAADAAVGRD
                     QRGIARQLRSELIMLSALPVAELRAQADVLARELRELDMRIQRANWEADLLD"
     gene            complement(16041..17438)
                     /locus_tag="H181DRAFT_RS14560"
                     /old_locus_tag="H181DRAFT_02930"
     CDS             complement(16041..17438)
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889625.1"
                     /locus_tag="H181DRAFT_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02930"
                     /product="L-serine ammonia-lyase"
                     /protein_id="WP_045864878.1"
                     /transl_table=11
                     /translation="MAISVFDLFSIGIGPSSSHTVGPMRAARMFARRLKNEGVLAHTAS
                     VRAELFGSLGATGHGHGTAKAVLLGLEGETPRDVDVETADERVEAVRSSKRLRLLAADI
                     GDAHEIAFDEQSQLLLHRRKSLPYHANGMKLFAHDASGGLLLEKTYYSVGGGFVVDESV
                     LDEGDGAASPIKLDDTGLRHPFRTGDELLRLTRETGLSISGLMLENEKAWRTEEQIRAD
                     LLEIWRVMQECVRRGLSREGILPGGLKVRRRAATAARQLRAEGSREVHAMEWLTLYAMA
                     VNEENAAGGRVVTAPTNGAAGIIPAVLHYYTEFVPGADEDGIVRFLLAAGAIGLLFKEN
                     ASISGAEVGCQGEVGSACSMAAGGLAEVLGGGPEKVENAAEIGMEHNLGLTCDPIGGLV
                     QIPCIERNGMAAVKAVTAARMSLRGDGRHHVSLDKAIKTMKATGADMKVKYKETARGGL
                     AVNVIEC"
     gene            complement(17634..18908)
                     /gene="glyA"
                     /locus_tag="H181DRAFT_RS14565"
                     /old_locus_tag="H181DRAFT_02931"
     CDS             complement(17634..18908)
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (78-369). E-value:
                     1.6e-12. Score: 39.1. Matches aSDomain:
                     nrpspksdomains_H181DRAFT_RS14565_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469891.1"
                     /locus_tag="H181DRAFT_RS14565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02931"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_045864879.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.5e-12, bitscore:
                     39.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLNSSLHEVDPDVAAAVDAELHRQQSTLEMIASENFAPVAALE
                     AQGSVLTNKYAEGYPGRRYYGGCEHVDAIENIARERIKTLFGAEAANVQPHSGASANAA
                     AMFALLKPGDTVMGLDLAHGGHLTHGMKINFSGKLYNIVAYRVDEESGRVDMDEVERLA
                     REHRPQMIIAGWSAYPRQLDFAAFRRVADEVGALLMVDMAHFAGLVAAGLHPSPVPYAD
                     VVTTTTHKTLGGPRGGAILSKQEFAKKINSAVFPGQQGGPLEHVIAAKAVSFKVASSDE
                     FKERQQRTLDGARLLAERLLKQDAVDAGISVLSGGTDVHLVLVDLRNSELDGQQAEDRL
                     HEIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFQEEDFREAADIIAEALLPTFDE
                     EKGKALGARVSALAAKHPLYPGLGK"
     aSDomain        complement(17802..18674)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H181DRAFT_RS14565_Aminotran_1_2.
                     1"
                     /evalue="1.60E-12"
                     /label="H181DRAFT_RS14565_Aminotran_1_2.1"
                     /locus_tag="H181DRAFT_RS14565"
                     /protein_end="369"
                     /protein_start="78"
                     /score="39.1"
                     /tool="antismash"
                     /translation="RERIKTLFGAEAANVQPHSGASANAAAMFALLKPGDTVMGLDLAH
                     GGHLTHGMKINFSGKLYNIVAYRVDEESGRVDMDEVERLAREHRPQMIIAGWSAYPRQL
                     DFAAFRRVADEVGALLMVDMAHFAGLVAAGLHPSPVPYADVVTTTTHKTLGGPRGGAIL
                     SKQEFAKKINSAVFPGQQGGPLEHVIAAKAVSFKVASSDEFKERQQRTLDGARLLAERL
                     LKQDAVDAGISVLSGGTDVHLVLVDLRNSELDGQQAEDRLHEIGITVNRNAVPNDPRPP
                     MVTSGLRIGT"
     gene            complement(18995..19375)
                     /gene="gcvH"
                     /locus_tag="H181DRAFT_RS14570"
                     /old_locus_tag="H181DRAFT_02932"
     CDS             complement(18995..19375)
                     /GO_component="GO:0005960 - glycine cleavage complex
                     [Evidence IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /gene="gcvH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469892.1"
                     /locus_tag="H181DRAFT_RS14570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_02932"
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="WP_045864880.1"
                     /transl_table=11
                     /translation="MSNPQQLRYSKEHEWLSAAEDGVSTVGITAHAADALGDVVFVQLP
                     EAGESVTAGEPCGELESTKSVSDLYAPVSGEITEINQDVVDDPALVNSAPFEGGWLFKV
                     RLSDEPEGLLSAEEYTAFASGS"
ORIGIN
        1 cttcaacgag tcgatcgtcg gagacgtcgt ggagatcaag aactccaagg acaagaccat
       61 ccagcccgac aacggactca acggctggaa catggactgg gacgagtgga aggctgagca
      121 ggactagcgg acagggccgg cggcacaagg ctgcccggga ccgacgccca ggaccggcga
      181 ggcgcccgcg gtctccacgg ctcgtggaga ccgcgggcgc ctctgctgtc gccggcgtgc
      241 gtctacgcgc tgtgcaccag ctggatcagg ttgccgcagg tgtcgtccag gaccgccgtg
      301 gtgaccgggc ccatctccag cggctcctgc gtgaagcgca ccccggcctc gcgcagccgg
      361 tcgtactccg cccgcacgtc gtccacggcg aaggacgcgg ccgggatgcc gtcctccgcc
      421 agcgccgacg tgtacggctt cacggcgggg tgggcgtcgg gttccagcag cagctcggtg
      481 ccgtcggggt cctcggggga gaccaccgtc agccagcggt gcgcgcccag cggaacgtcg
      541 ttcttcttcg cgaagcccag cacgtccgtg tagaagcgca gggcttcttc ctggtcgtcg
      601 acgaagacgc tcgacaggtg gattctcatg gtgtgccctc cggtgcgtca ggtctgagcc
      661 accgtgccgc gatgtgctca aggggttcgg tgtcgaggtc gtggaacttg tagcggccct
      721 ggcgccgcga acggaccagg cccgccgact ccagcacggc cacgtgctgg ccgatcgcct
      781 gccgggacag cccgatgccg tgcttggaca ccagccgcgc gcagatctcg aacagggtct
      841 ggccgtcccg ttccaccagt tcgtcgagga tgcggcgacg ggtggggtcg gccagggcct
      901 tgaagacgtc ttccgccacg gccaccagca taggaaagtg acggctttcc tatcaagcgg
      961 tctgccggac cggtcttcgg cggttctgcg gccgctcccg gcccggggcc gctcccggcc
     1021 cagggccgtt cccggcccgc ggtgaggaac ggcaccggag gccccgccgg taacggccgt
     1081 taaccttccc ccatgactgt gaatctcgaa gtcgccgaag gcgtcggcac gatccgcctg
     1141 gaccgtcccc cgatgaacgc cctggacgtc gccacccagg accggctccg tgagctcgcg
     1201 gaagaggcgt ccgtacggga ggacgtccgg gccgtggtga tctacggcgg ggagaaggtc
     1261 ttcgcggcgg gggccgacat caaggagatg caggccatgg accacgcggc catggtgtcg
     1321 cggtccaagg ggctgcagga ctccttcacg gcggtcgccc gcatccccaa gcccgtcgtg
     1381 gccgccgtga ccggctacgc gctcggcggc ggctgcgaac tggcgctctg cgcggacatc
     1441 cgcatcgcgg gcgagggggc gaagctgggc cagccggaga tcctcctcgg cctgatcccc
     1501 ggtgccggcg gcacccagcg gctctcccgc ctggtgggcc cctccaaggc caaggacctg
     1561 atcttcacgg gacgtcaggt gaaggtgccc gaggcactgc agatgggact cgtcgaccgg
     1621 gtcgtaccgg acgaggaggt ctacgaccgg gcgaaggagt gggcggcgcg gctggccgcg
     1681 ggcccggcca tcgcgctgcg tgccgcgaag gagtccgtcg acgtgggcct ggagaccgac
     1741 atcgacacgg ggctggccgt cgagcggaac tggttcgccg gccttttcgc cacagaggac
     1801 cgggcgacgg gcatgcgcag cttcgtcgag gagggcccgg ggaaggccaa gttccgctga
     1861 ccgtcccggg gttcggggcc gtgtccgtcc ggcggagccg ccgggccggc ccggcccggg
     1921 ccggccggag cctccggtgc cgtgcggagg gcatcccgcg ggtgactcgc ccgcgccggt
     1981 gccacggtgc gcgcggctcc tcccgcgcgc gccccacctt gtgggggaat gggcgagaac
     2041 tcgcccccgg cgccgtaggc gcaccccgca ccgtccggcg tttcccctcc tgcggtgcgt
     2101 cgtccctggt cgccggggcc tcgcggcgcg ggacgggtag cgggccgcca agtggggacc
     2161 ggtgccgagc agttggttcc gccgccggga tctgaggtaa cagccccacg actccccagc
     2221 tcccgccatg atggtggcca tggcgggaca gggagaagtg gcgagcgtga ccgagcgagt
     2281 gccagaagtc ccgggtgaac cggcgagcga cgactcggcg aacagcgtcc tcgaactcgt
     2341 cggcgacccc acgatcgcag aggtgcggct gccgaaccgc cccgagtccg cgcgctgcgc
     2401 acgcgagatg gcccgtacgg tgaccgagtc gcactggggc cttcccggcg cgctcgtgga
     2461 cgacgccgtc ctgctggtgt cggaactcgt cggcaacgcc gtacgtcaca ccggggcgca
     2521 cgtcttcggg ctgcgcatga tgagacggcg cgactggatc cgcgtcgagg tccgcgatcc
     2581 ctcccgcggc ctgccctgcc tcctgcccgt acacggcctc gacaccagcg ggcgggggct
     2641 gttcctcgtc gacacccttt gcggcaggtg gggtgtcgac ctgctgcccc gcggcaagac
     2701 gacctggttc gagatgcgga tcaccggttc ctgacgtggt gtcacctttg tgcgcgacca
     2761 cccggtagca cgctccgaca gtgctactgt gcgccgctga acgggagtta tcggcgcgcg
     2821 gcgtggaggg gggcagcgct gtgccagaca gagatacggg gacagatgac cgtgcggtac
     2881 cggtacgcga ggtcgaagcg gccgttcctt tgcacgacgt tgctgactct cgccctcctc
     2941 acgggatgcg gcggcgaggc cggcggcggc agtgagggcg ggaagtccgc cgacggggcg
     3001 ggcaacgcct cgggcggcaa ggacgactcg ccggggtccg ggaaggcggg cccctcgccg
     3061 gacgcggccg acggcagcga cacggacgcc tgccgcgatg cggaatgcga ggtcgtggtc
     3121 agggcgggag acgtgctgcg gcccaagacg tcgtacggcg tccaggagtt caccgtcgag
     3181 ctgatcaaca agggagtggt ctcctggcgg acggtgttca ccaccgggtc cggtgccatg
     3241 cagacccggg gttcgtccgt ctcctcgacg agctgtacgg gcggtgagtg caacggcagg
     3301 ctcggcagga cgcagggcag gctcgagacc gacaagctca tcatcgactt caactcgatc
     3361 gacgacgaca gcgcagtggc gaagctgacg gcgaagaagt agcaccgggg cccggccgcc
     3421 ggcggcccag ccccgcggag cgggccccgt ggactcgcgc acgaccaggc gcagtgcggc
     3481 cacatcggag acccgcaccg cccagcaggg cgagcagccc ggcggcgccg gaccggcccc
     3541 gttgctcggc ttcccggccc accgtcgtca ggcgcggatg gacgatctcc ccgggcggca
     3601 ggtcgtcgta gccgatcacg gacacgcgcg gcacctccgg cccgagccgc cgggccgcgc
     3661 tgacgccggc caccgccacg gtgccgttgc cgaagacgat cgccgtgggg cgctggtcgg
     3721 ccggttcggt caggttcccc acggcctccc cccccgtcct gcccgtcgaa ccggacggcg
     3781 ccgaggtcgt cgcgcgggac gcgcacgggc gtctgcacga ggagccgctg acggcggagc
     3841 cgcgggtgac ggccggcacg ctgaccggcc tggacggcct cccgccgggc acgctggagc
     3901 tgccccccta cggcgtcgtc gtcgccgaac tgacagcctg aaggggcgcg gccgcggtcc
     3961 ggcggccgcg gccgcgaaga ggagaggagc agctccacca tgaagatcga gtccgccgag
     4021 accgtcgtca ccagcccggg gcgcaacttc gtcaccctgc gtctggtcac cgccgacggc
     4081 gtcaccggtc tgggcgacgc cactctcaac ggccgtgagc tcgccgtcgc ctcctacctg
     4141 cgcgaccacg tggcgccgct gctgatcgga cgggacgccc gcaacatcga ggacacctgg
     4201 cagtacctct accgcggcgc gtactggcgg cggggccccg tcaccatggc cgcgatcgcc
     4261 gccgtcgaca cggccctgtg ggacatcaag gccaaggccg ccggcatgcc gctgtaccag
     4321 ttgctcggcg gcgcgagccg ccgcggcgcg ctcgcctacg gtcacgcgtc ggggcgcgac
     4381 gtccccgaac tcctcgactc cgtgcgggcc cacctggcgg acggctaccg cgccatccgc
     4441 gtgcagacgg gcatccccgg actcgactcg gtctacggag tggcgtcctc cgccgccggt
     4501 tcgggcgagc gttacgacta cgagcccgcg cgccgcgcga ccggggggcc ggtgctgccg
     4561 gtggaggaga cctgggacac ccgggcgtac ctgcgccacg tgccgtccgt gttcgaagcg
     4621 gtacgcgagg agttcgggcc ggagcttccg ctgctgcacg acgggcacca ccggatgacg
     4681 ccgatccagg cggcgaagct gggcaagtcc ctcgaaccgt acgacctgtt ctggctggag
     4741 gacgcgactc cgggcgagga ccaggcggcg ctgcggctga tccggcagca caccacgacg
     4801 ccgctggcca tcggcgaggt cttcaactcg gtgcacgact acacgacgct gctcgccgag
     4861 cggctgatcg actacgtgcg ctccgcggtc acccacaccg ggggcgtcac cgccatgaag
     4921 aagctgctgg acatggcggc cgtccacggc atccgttccg gcatgcacgg cccgacggac
     4981 atctcccccg tgggcatggc ggcgcagctc catctcgacc tcgccgtgca caacttcggc
     5041 atccaggagt acatgcgcca ctcgccgcac tccctggagg tcttccgcac ctcctacacc
     5101 ttcgaggacg gcctgctgca cccgtcggac accccgggtc tgggggtcga actcgacctg
     5161 gacgcggcgg gccgcttccc gtacgagccc gcgtacctgc ccgtgaaccg gctcgcggac
     5221 ggcaccgtgc acgactggtg accggcggcg ccgggcaccc cgcgtggagc ggggagggtc
     5281 agcgcttcct gtaccccgcg ccgaccttct ccgcttcccg ctgccccttg cggagcgcgt
     5341 catcgacggt ctggtcgccc gcgatcgccg cgctcagctc ctcggagacc ttgtcgccga
     5401 gggccgtgaa ctcggggacg ccgacgaact ggatgcccgg ggcgggacgt tcctgcacgc
     5461 ccggactccg cgggtccgcg tcgccgatgg cctcctcggt gacctcggcg aaggcgtctg
     5521 cggccttcct gtactggggc cggtcgtacg tcgaactccg cttgcccgcc ggcacgttgg
     5581 cccagccgaa ctcgcggccg acgagtgcct cgtactcctt gccggaggcc caggagatga
     5641 acttccacgc gtcgccgggc ttctccgagg acttctggat gccccatgcc caggtgtaga
     5701 gccacccgga ggagcgggtc ttctcgaccg gagcgggcac gtaccccatc ttgcccttga
     5761 cgggcgaggt gccggcctcg agggaaccgg ccccggcggt cgcgtcgtac cacatggcgg
     5821 acttgccgcg cttcatgttg cgcaggcagt cggcgtaccc ggtgcgggac gggtccggct
     5881 cgccggactc gcgtacgaga ccgacgtaga actccgcggc cctcctgaac gcgggggacg
     5941 tcagacgcgc gttccagcgc ttgtcgaacc aggtcccgcc gaaagtgttc acgacagtgg
     6001 tgaacggggc ggtcatctcg ccccagccgg ggagcccgcg caggcagatc ccggtcatgc
     6061 ccttctccgg ccggtcggcc ttctccgcca gctcggcgac gtccttccag gtgggccggg
     6121 cgggcatctc caggccgagc tgctcgaaga cgtccttgcg gtacatcagg aaggacgact
     6181 cgccgtagaa cggctccgcg tagaccttgc cgtccccgcc gctgagggag agctgcagcg
     6241 gcagcaggat gtcggactgg tcgaacgcgc ggtcctcggc tatgtacggg tcgagcggtt
     6301 tcagccagcc tcggtcggcg taggtctccg tttcgaagtt gctgacggtg gcgacgtcgt
     6361 agcggccgga ctgcgcggag aagtcgtcgt gaatgtgctt gcggacctcg ttctcgggca
     6421 ggggcgtgaa gtcgacctcg atgccggtcc tcttcgtgaa gtagcgggcc gtgagcttct
     6481 ccagctcctg catctgcggg ttgtcgacca tcagcacccg gacgacacgc tcgtccgggg
     6541 ggccttcgtc caggccgcac gccgtgagca tggccgcgag tgcgacggcc gccgccgcgc
     6601 cgcgtgccgc tcttcctgcg agtaaggaca ttcccactgc tctcctcgtc gtgatcgttc
     6661 cgcggtcccg cgagggcgtc cgacggctgc cccggtgggg agccgtgccg cccggagagt
     6721 tctacatgcc cgaacggggt gtgatccggc ccggagcgac ggcgatcgcg cctgcttccg
     6781 cctgctccgg agggcatcgt tccccctccg ggctgcggag gacccccgga gggcgcgcca
     6841 cggccgaccg ccaccgccgc cggggacgcc cgcgtgcggt ccggtgcgcg gtccgcggcg
     6901 cgggagccgc ggccgaccgg gaagggacgg tcgtgccgtt ctgcgaccgg acgtggaggg
     6961 cgccccgggg agggggcacc cgtagcgcgc ggtgacgtgt gctgacagcc gcaccggtgc
     7021 cgtccgggcg ctcagccggc cgacggtgtc cggggaccga ccgaacgccc gggcaccgcc
     7081 ggccggcggg ggagcggtgc gagacccacc ggggagcggc cgccggaggc ggcgccgagg
     7141 aggggagccg ccttgcgcgc acgccttccg tggtagacga gcgcgggcgg cagattgccc
     7201 cacacggtgc ggcccgcgac gacttcctcg aacgcctcgt ggagcatgcg ccggaagcgg
     7261 agcgccggcg cgaggcgcct cgcgtgcagg tacccgaacg tggtgaaggc gccctcgggc
     7321 gccagcaccc ggctgatggc cgagagggtc tccgactgca ctgtgcgggg gaacgaggcc
     7381 cagggcagtc cgctgacgac gacatcggcc ctttcgtggc cctgctcggc gagcagctgc
     7441 ggcagctgtg cggcctgggc gttgagcacc tcgacacccg ggaagcggtc gctgagcctg
     7501 cccgccagct gcgggttgat ctctatcgcg agatggcgtc cgcgtccgcg cagctgctcc
     7561 tggatggtgc cggtgaacgc gcccgtgccg ggaccgagtt ccaccaccac ggggtccccg
     7621 cgttccggaa cgggggccgt cacggcttcg gcgagtctgc gggagctggg ggccactgcg
     7681 ccggtgtcga tgggcgaccg caggaactcg cggagcatgg tgccggtctc gctcgtcaaa
     7741 ctcatggcct ctcgggatcg gtcgtcggtg cgttccgaaa gtctcgctgc gcgcacggat
     7801 ccctggagac gcggccggct cgcgcgcagc tcgaagcggt ggcggtacga cggcgccgag
     7861 cggcccagtg cgcttgcggc cccaccgtac ctacggcccc aggggccacg aagacgggtc
     7921 gcggtacgga gacgagaccc acacagcagc tcctccggtc ccaccggcca ctcccgtccc
     7981 ggcgcgcggc cgcgttccgc ttctcccgct catggcccgc tgccgccggt gggacgcccc
     8041 ggttcgcccc ggtcaggagg gccgcccccc gaactgccag ctgtgcacgc cggcctccgc
     8101 gtaggcgtcc gcagtgagga cggcgggcgc cgccgccgga tccggcgccc cgaccagtgc
     8161 ggcggtgccc acccaggtgc ctccgtcgtc ggacagcagc ggcccgtacg cgatcagctc
     8221 gtcccggccg ggcggaacgg cggtgccggc ggcctcgccc gcgccgaggc cgagcaccgg
     8281 acagcggttc ccgccgctcc gcccgccggg gaagccccca tcgtgcgacc cagcagcttg
     8341 cgccaccggc gcagcagcaa gaactccatg cccgggagtc ttccggggcg gtggtacggc
     8401 gtacagcgga catcggcggg cccggcccgc acggccgcca gggggcgagg cgccggtcag
     8461 cgcccgtacg gcccgccctc gcgcgccccc ggctcagcga gcgcggtcac tgcgcggagg
     8521 tccgctgccg ctccacggcg accagggcgg cgtcgtcccc gagccgcccg ccggtgtggg
     8581 cgagcaggtc gcgcttcagg tggtgcagca gcgcctccac gtggcagtcc gtccagctct
     8641 ccatgcgtgc ggccagcgga tagaagaccc cctccgggtc gcgggcctcc gtgacgccgt
     8701 ccgtgtacag cagcagcctg tctccggcgc cgagggtgaa ctcctccacg tggaagtgcg
     8761 cggcggacag ttcgccgagg cccatgggag gcgcggggcg gggggcctcg acggtggaca
     8821 cgcggccgtc gcgcacgagg atgggcggag ggtgaccgca gtcgaccatg cggaccgtgt
     8881 cgtcctcgtc agggatttcg acgatcgcgg ccgtgatgaa gctttcgccg ggctcgtcgc
     8941 tctcggcgcc gtcggcgagg ctccacgtga cgctgctgtt cagatgcgcc gccagcgcgt
     9001 cgaggggcgc ctggcggtgc ccggcgaggt ggaacgcgtc gagcagcagc gcggcctcac
     9061 cggcgagggg catgcccttg ccgcgggcgt cgccgatgag caggcgggta ctggagtcgg
     9121 tgcgctcgac ggcgtacacg tcgccgccga tacgggcctc ggcctccgcg ccgaggtaca
     9181 gggaggcgac cctgaggggg ccgatcctct tgggcagcgg tctgaggatg aggcgctggg
     9241 ccgtctcgga gacgtggcgg acctgccgca gctcccggtt ccgccgctcg cgcagcaggc
     9301 agaacagcac gaggctggcg cccaccacga ccagcgcgac gatctgcgcc tggtggttgg
     9361 ccgagaagag ctggcgatcg tcgcggagca ccgcgatgac cgcctgtgcc gccaccgcga
     9421 gcacggcgac gaaggcggtg aggcgggcgc cgccgaaggc cggcgtgatc gcgggcgctg
     9481 cgaccagcag ggggcccaga tggatgtggg gaggcgcgag gacgtcgacc accacgatcg
     9541 tgatcagcag cgcgaccggg aggagcaccg ccgcccgcgg ggaccgccga agatcaacga
     9601 accgtagcgc catacctctt ctgtacaccg ccggtgaggg ccgcgcaccg ggaggacggg
     9661 gcgagcccgg acggggcccg cgcggcggga gcctggcccg cggacgcccg cctgcggcgc
     9721 cgggcgtcgg gtcctcccgc ctgcggcagg tgaccgccac ctacggggac agctcgctgt
     9781 tctccgtccc tgccggccgg ccggaccgcg ctccgtgtcc gacgtccgcg gcccgtacga
     9841 cgtccgcggc ccgtacgacg tccgccgcgc ctccgacgtc cgccgcgcct ccggcgtgcg
     9901 cgagcgtttg cgtcctgcgc aggcggggcg cgcgtcccgg gtctccccga cggggggcgg
     9961 ggccccgggc acgcgcgccc ctcttcccga ggagcgccgg tcaacccgcc cgtacgtggc
    10021 tggggaccgg gtccatcggg gtataggggg agatgaacat catctccggc tcctcgctca
    10081 tgtcgtagcc ggtggagcgg gcgaaggcga actggaaacc cttcgcccgc gtaccctccg
    10141 cggactcgcg gatctcgcgg cgcaggtagt tcacgagcgt gcggtacgag ggaagcttcg
    10201 tcacgaccgg aaagccctcc ggcaggttgc ggaggatctc gtcgcccacg tcgaagatcg
    10261 ccttgccgag cctgcggtcg gggaaccaga tcgcgtgctg caccgtgcgg tcgggcgtca
    10321 gcgacagctg cgtccagtcc gacgtctcgt cgtcggccga gagggtccgg tagagcaggt
    10381 gggagtcgtg tatcgccgga tgcggggcga agaaccgcca attggggacg acgctcagcg
    10441 ggtccctcgt ccggatgcgg ttgaagagct gatgcgggtg ctgagcggcg accgtggtgg
    10501 cgatcagggc ggcgccggcg aggcgccatc ccgcgcccgg gccacgcacc gcgtcccgca
    10561 gcgtggcggc gaggctcatt tcgaggccct ttcctgctcg tcctgttcct gcccgtcctg
    10621 ttcctgctcg ctggcggatc cggcggatcc ggcggacgtg ccgctcccgg cggcgaacgc
    10681 ggcgatggcg ctcgcggcgc ggatcgcgta ctccgccgag gacagcagcc cgtcatgcgt
    10741 ggcgccctcg atgacgaccg aagacgcccc gccctgatgg gacttggcca actcgtcgtg
    10801 catgagcagc tgttcggcat cccggtcgac cgtcgcctgg gcggagacga ccaggccccg
    10861 gcccggtgcc ggcggaaggc cgccgctgaa ctcgctgaac tccgcctcca ccgcgttcca
    10921 ttcacgcgcc gccgccgacc acagcctgct gtcgcagtac tgggcgaagg cgcgctccct
    10981 ggtgtgcacg ggcagatcgt cgacccaatc gggacggctg agcagcgcgc cgctgcccga
    11041 gcggaggtac cacgtcatct gcgtgaagag ctccctgagc cgcggcgagc tctcggactg
    11101 ctgcggggag cggttgagct cgtcggggtg ggaggagtcg aggtacacca cgccctccag
    11161 ccggtctccc agcagcggcg cggcgcgccg cgcgatctcg ccgccgagcg agtgcccggc
    11221 caggatcacc ttgcgccccg cgccgaccgt ggcaccgacc aggtcgacca ggtcctccac
    11281 cgattcctgg atgcggtagg cgcccgcggc ctcgcggacg gagcccgcgt agccggcgcg
    11341 ggcgtaggag acgagcccca gcccggtgcc cgatccgagg tggccggtca tccaggagaa
    11401 gtgctcgggt gtggctgcca ggccggtctc gaagaccacg accggcttgc ccgcgtcgcc
    11461 ctgtgcgtgt acgcggtact gcagccggtt gcccgaactc gccgtgtgcg tacggcagtc
    11521 cggcggaccc tcgaggacgc gggaccgccg ctgcaccgcc gtgaccacgg ccttgccggc
    11581 cgccgcggcc agagcggcgg cgacgacggg cagcatgcgg tcgtcccgct tcgcgccgga
    11641 ggggtgcgtc ctgggcacgg ccgtgtaggc gacgaggggg tgcatggagg ggaaggcggt
    11701 gaggaaccgc ccgagcccca tcaggtaggc gttcgccccg tggaagagca cggccgaccc
    11761 gagcacgggg cgggcgaggc gtcccccgaa ggcgtacagc acggggaagc cgcattcgag
    11821 ggcgagcacg gagtgggtca ggtacttcgc cgccgtcggg tgcttctggg tccaggacca
    11881 catgccgcgg tggccgtacg tgcgcgtccg catcacgccg ggcagggcgg agccgtcgcg
    11941 ccacgacttg ccgaagagct tcacccagcc cgagacggcg taggagaggt tggactgcac
    12001 cgcgacgtac cagatcaggg cgtccttggc ctcttccgac ctgacgagcc gggcggcgcc
    12061 ggtggcgccc tgcaccgtga gggagacctg gtcggttccg tcggtcccgt acaggtggcg
    12121 ggggtaggag agcatccccg tcgccgagag gtagaggttc gcggcgccgc gccacctctg
    12181 gttcccgggc atcaggaggg ccgcggccac cgctgccctg ctcgcgtgga cggcggtggt
    12241 gacacggcgg tcggagacgc cgtcgagaac cttgcgcagg aggggactgc gtccgcgctg
    12301 ggcgtcgcgg aggatctccc agtcgttcat gccgcccgcg tcggtctgct tcctctgcgt
    12361 caggtattcg agggaggagt tcagcgtggt gagcgcgccc aggcgttcgg agatgccgat
    12421 ggcgcggtcg cgtgacaggc tcgggggctt cagcacggtg cgggcgagcc ggcgcagagg
    12481 ccctgtgttc cttcgcatgt tcgtatcccc ctcgtggtgt cggaagctcg gtgacgtgac
    12541 ggagccggcc gtggccgagt acggcggacg cggcatcccg tcgaccgccg tcacggaagg
    12601 cggctcgggc gggacgtgtg tgtgcgggcg ccgaacgcag cgccgcgggc gcggagtcga
    12661 cccgtcggcg gtgcgtctcc ggggcgcacc cgccgtgaag tgcggcgtat cctctacgga
    12721 aagggcctgt gtgcacttcg actgcacaca ggcccctccc gaacgtcagg ctgctgccgg
    12781 gcccgtggga agctcgggcc acgcggcgtc agttcagccg acggccttgg tgacggcgac
    12841 gccggtcgcg aaggcgacgg tggcggcggc gaccggggtc gccaggacgg ggccctgggg
    12901 cacgacgacc tggcccttgt ccgactccga cagcttcggc tcggccttca cgatgatctc
    12961 gcgcatagtg atcgctcctt gtgtgagaga gacttccttc ttcaccccgg cccccgtgat
    13021 gtcacgtgaa cgagagggat cccggccccg gctacctcta ccaccggtaa cgagtgacgc
    13081 cggtcacgga ggggatgaaa gcagcaccga accggggtgc gtatgacgcg gatcacagca
    13141 cgaacggaca ggcctgttcc gcttgtctga cgtcggtcac gggccgcgca tgacaggtgt
    13201 cagggcgtgc catgagtcaa ctcatgcctt gagcatggga tttgaggttg tggagacggg
    13261 gccggagcgc ttcgcggagc ggaatgtgac cgacgccaca ccatcgggcg tgcctcccgt
    13321 gtccatatgc ggaggagctt tctccgctta actggcatct gtcatggggc ggttgtgaca
    13381 ttcggcaagg tgtttgatga acctcctcac gctccagatc cgggcggctg acgagaattg
    13441 acgcgtgaga accaccgaga ctgagcacgc gtcacaagcc cgcgccccgg agcgccgcgg
    13501 cgccacgcga agggcgtcag gtggtccccc gggcgtccga ggcgctgccg ggcctcccgc
    13561 tggcggcgtc ctcccacggg cacacggcgg cgagatgcac gggcaggcgc tcctcgctgc
    13621 gggaacgccg tagcgccgct cacccgcact ctctcccccg caacttcgcg gcgcgttccg
    13681 gggatggacg cgcccgcggg gagcccggcg tcggccgggc tgtgcgttcc gcccccaccg
    13741 gccaggggac ggtacgaccg cggggctgga ccgcgtggcg gcgacaccgg acgaccgcac
    13801 tgccggccgg ccgtgccgcc gaccacgtat cgagccctcc catcgcaacg cacccgctcc
    13861 cactccggga aggactgagc cgtggcaata cgcgtcctac tggccgatga cgagaagctg
    13921 atcctcgggg ccctctcggc cctgctctcc ctcgagaacg acatcgaagt ggtggccgag
    13981 gccgacaacg gcacgacggc gctggaactc gccggcaccc gcagtccgga cgtctgcgtc
    14041 ctggacctgc acatgcccgg caaggacggc atcaccgtca cccgcgacct gcagagtgcc
    14101 gtgcccgccc cccgctgcat ggtgctcacg tcacacgcgg cacccggata cctcaagtcc
    14161 gcgctgaagg cgggagcgag gggcttcgtc cccaagacga cctccgcgca gcggctggcg
    14221 gacatcatca gggacgtcca ccggggctcc cagtacgtcg acccggacat ggccgcggac
    14281 gcgctctcct cgggggactc gccgctcacg cggcgcgagg cggacatcct caccctggcc
    14341 gcggacgggg ctccgatcgg ggagatcgcc cagcgggccg ctctgcgccc ggggaccgta
    14401 cgcaactacc tctcggacat catggggaag ctggaggtcg ccaacaggca cgaagccgtg
    14461 cacgccgcgc gccgcttcgg ctggatctga gctccgccgc cgctccgtcc cgtcgggccc
    14521 ctgaccggac gggcggggcg gccagcggct cgcgggcggc ggtgtcagcg gcgccgcagc
    14581 ggctcgcaac cctgcacggt gagcgtgccg tccccggccg acagggtgat gatgatccgc
    14641 tcgttccggt cggcggtctt ggcctgcggc atcttgtcgc ccttcggctc ggtggtgatg
    14701 aggcagccct cgacgacgtc gtccttcgcg ccggcgctct cgtacgtgcc cgccgggatg
    14761 tccctgccga cggtgtagtc cccgtcgccg tagctcttcg ccgtgtcctc ggccgtcggc
    14821 tcggggctgc gctcggtcgg cgtcgccgac gtctcgtccg gggcgggccc gccgctctcc
    14881 tcacctccca tggccacgaa ggtgatgacg acgacgaggg cgatcacggc gatcaggccg
    14941 aggcagccga agcccaggat cttccccttg ccggacttct tgcggcggtg cggatggtgc
    15001 gggggctggt ccggccggtt ccactgggtc atggcgtccc tcctgcgggc ggccgccggt
    15061 ggctggaggg gaggggccgg cgtcgttccg cccggtatca ggctgcaccg cggcgggggc
    15121 caccgcaccc ggagacacct ccgaccgggc cagtgcgtgc gctccccgcg cccggcggcc
    15181 gggcggggcg ttcaccgttc cgggcgttca ccgtccctgg ccgtccaccg ctcgtcgagg
    15241 acatctgcgg ccgacctggc cgaaacccgg gtgcgtgacg atgttgtacg cccgcatact
    15301 tgtgcggaat gagccagcaa cggggaaggc agaggcagtt gaagctcgca gaggcgttgg
    15361 ccgagcgcgc ggacgcaacg cggcgggtgg agcagttgcg tacccgcgcg gtgagcagcg
    15421 cgcggtacca ggagggcgag acccctccgg aggactccgc ccggctgctg gcggaggcga
    15481 acgacgtcct cgacacgctc gagtcgctga tccgccggat caacaggacc aacgccaccg
    15541 tgctgatcgg tgaggacggc accatcaccg acgccctggc gcgcagggac gtgctccggc
    15601 tgcggcactc ggtgatcaca gctgccgcgg atgccgcggt cgggcgggat cagcggggta
    15661 tcgcccgcca gctgcgatcc gagctgatca tgttgtccgc gctcccggta gcggagctgc
    15721 gcgctcaagc cgacgtgctg gcaagggagt tgcgcgaact cgacatgcgc atccaacggg
    15781 cgaactggga ggcggatctc ctggactgag ggcgaggaac gacgcggagc aggtagtcgt
    15841 accggaggcg tgcacacacc gcggccggcg gttcatccgg cctctcctgg cgcgtggaga
    15901 gcagcgcggg gggttcgatt cccccagtca tatggcagct cagcaaggcg cacaggtgac
    15961 cgtgcacgac gcacaacgca tcaccacgtg cagatccggg acggtgaggg cgggtacggg
    16021 gctctccgcg cggaaactcc tcagcactcg atgacgttca cggccagccc gccccgcgcc
    16081 gtctccttgt acttgacctt catgtcggcg ccggtggcct tcatggtctt gatggccttg
    16141 tcgagggaga catggtggcg gccgtccccg cgcagcgaca tccgggcggc ggtgacggcc
    16201 ttcaccgccg ccatgccgtt ccgctcgatg caggggatct ggacgaggcc gccgatgggg
    16261 tcgcaggtca gcccgaggtt gtgctccatg ccgatttccg ctgcgttctc caccttctcg
    16321 ggaccgccgc ccagcacctc ggcgaggccg cccgcggcca tcgagcaggc cgagccgacc
    16381 tcgccctggc agccgacctc ggcgcccgag atcgacgcgt tctccttgaa cagcagtccg
    16441 atcgcgccgg cggccagcag gaaccgcacg atgccgtcct cgtcggcgcc gggcacgaac
    16501 tcggtgtagt agtgcagcac cgccgggatg atcccggcgg cgccgttcgt cggcgcggtg
    16561 acgacccgtc cgcctgccgc gttctcctcg ttcaccgcca tcgcgtagag cgtcagccac
    16621 tccatcgcgt gcacttcgcg gctgccctcg gcgcgcagct ggcgggcggc cgtcgcggcc
    16681 ctgcggcgca ccttgagccc gccgggcagg atgccctcgc gactgaggcc gcgccgcacg
    16741 cactcctgca tgacgcgcca gatctccagg aggtcggccc ggatctgctc ctccgtgcgc
    16801 cacgccttct cgttctccag catcagcccg gagatggaca ggcccgtctc acgggtcagg
    16861 cggagcagtt cgtcgcccgt gcggaacgga tggcgcagcc cggtgtcgtc gagcttgatg
    16921 gggctggcgg cgccgtcccc ctcgtcgagg acggactcgt cgacgacgaa gccgccgccc
    16981 accgagtagt aggtcttctc cagcagcagg ccgccggacg cgtcgtgggc gaagagcttc
    17041 atcccgttgg cgtggtacgg gagcgacttg cgcctgtgca ggaggagctg ggactgctcg
    17101 tcgaacgcga tctcgtgggc gtcccctatg tccgccgcca gcagccgcag ccgcttcgag
    17161 gagcgcacgg cctcgacccg ctcgtcggct gtctccacgt cgacgtcgcg cggggtctcg
    17221 ccctccagcc ccagcagcac ggccttggcg gtgccgtgcc cgtgccccgt cgcaccgagc
    17281 gaaccgaaca gctccgcccg caccgacgcg gtgtgcgcca ggacgccctc gttcttcagt
    17341 cgccgggcga acatgcgggc tgcgcgcatc ggtccgaccg tgtgggagct ggacgggccg
    17401 atgccgatgg agaagaggtc gaagacggag atcgccatgg cggcggcctc ctttccttgc
    17461 gtgcggttcg gttcggtgcg ctggagtgcg gcggcgggcc cccggcggca gtggccggcg
    17521 ccgcctccgg tgccgacccg gagggacgcc gcggcggtat gcctgcggcg tgccctccgg
    17581 ttgcggcgcc gtgtcacggc gccgccccac ggcgtgaggt cacccgctcc cggctacttg
    17641 cccagcccgg ggtagagcgg gtgcttggcc gcgagagcgc tgacgcgtgc gcccagcgcc
    17701 ttccccttct cctcgtcgaa ggtcggcagc agcgcctcgg cgatgatgtc ggcggcctcc
    17761 cggaaatcct cctcctggaa gccgcgggtg gccagcgcgg gcgtgccgat gcgcaggccg
    17821 gaggtgacca tgggcggccg gggatcgttg ggcaccgcgt tccggttgac cgtgatgccg
    17881 atctcgtgga gccggtcctc cgcctgctgg ccgtccagtt cgctgttgcg caggtcgacc
    17941 aggacgaggt gcacgtcggt gccgccggag agcacggaga ttcccgcgtc gaccgcgtcc
    18001 tgcttcagga gccgttcggc gagcagccgg gcgccgtcca gggtgcgctg ctggcgctcc
    18061 ttgaactcgt cactcgacgc gaccttgaag gagacggcct tcgccgcgat gacgtgctcc
    18121 agcggaccgc cctgctggcc cgggaagacc gcgctgttga tcttcttcgc gaactcctgc
    18181 ttggagagga tcgcgcctcc gcgcgggccg ccgagcgtct tgtgcgtcgt ggtggtgacg
    18241 acgtccgcgt acggcacggg cgaggggtgc agccccgcgg cgaccaggcc ggcgaagtgc
    18301 gccatgtcga ccatcagcag cgcgccgacc tcgtccgcga cgcggcggaa ggcggcgaag
    18361 tcgagctggc gcgggtacgc ggaccagccg gcgatgatca tctgcgggcg gtgctcgcgg
    18421 gcgagccgct cgacctcgtc catgtcgacc cggccgctct cctcgtcgac gcggtaggcg
    18481 acgatgttgt agagcttgcc ggagaagttg atcttcatgc cgtgggtgag gtgcccgccg
    18541 tgcgccaggt cgaggcccat gaccgtgtcg cccggcttga gcagcgcgaa catcgcggcg
    18601 gcgttggcgg aggcgccgga gtgcggctgc acgttcgcgg cctcggcgcc gaagagcgtc
    18661 ttgatgcgct cacgggcgat gttctcgatg gcgtcgacgt gttcgcagcc gccgtagtag
    18721 cggcggcccg gatagccctc ggcgtacttg ttggtgagga ccgacccctg ggcctccagg
    18781 gcggcgaccg gagcgaagtt ctccgaggcg atcatctcga gggtggactg ctggcggtgg
    18841 agttcggcgt cgaccgcggc ggcgacgtcc gggtccacct cgtggagcga gctgttcaga
    18901 agcgacatgg aaccatccct agtggcgggc cgggcaggca ctgtggcggg cagtgggcgg
    18961 ggactcgggc ggatggggcg ggcgcggcgc gcggtcagct gccggaggcg aaggcggtgt
    19021 actcctcggc ggagagcagc ccttccggct cgtccgagag ccgtaccttg aacagccagc
    19081 cgccctcgaa gggtgcggag ttgacgaggg ccgggtcgtc gacgacgtcc tggttgatct
    19141 cggtgatctc gccggagacc ggtgcgtaca gatcgctcac cgacttcgtc gactccagct
    19201 caccgcaggg ttcgcccgcg gtgacggact cgcccgcctc cgggagctgg acgaagacga
    19261 cgtcgccgag ggcgtccgcg gcgtgcgcgg tgatgccgac cgtcgagacg ccgtcctcgg
    19321 cggccgacag ccactcgtgc tccttgctgt aacgcagctg ctgggggttg ctcatggtgc
    19381 gattctcctg gatgtgaggg ggacgaggaa aacggtcttg gccagtggga cgggcgccgc
    19441 acgcccggac ctgcggaccc ggggcggccg ggcacggagg tgatccttcc caggcggcgc
    19501 cgcggccacg acacccggca ctgtgggatc ggcgaccccg gcccgcctgg gcttcagcgc
    19561 tgccgcttgt agaaggggag cgccacgacc tcgtacggct cgtgcttgcc gcggatgtcc
    19621 accgcgacgc cctccgtgcc gggctcggcg tgtgccgcgt cgacgtaggc gatggcgatc
    19681 ggcttgccga gagtcggcga gggagccccg gaggtcacct cgccgatgac cgagccgtcc
    19741 gcggcggaga ccacggtgta tccggcgcgc ggcacccggc ggccttccgc gacgaggccg
    19801 acaagcttcc gcgggggcgc ctgctcggca cgcgcggcgg cggcctccag gggctcacgg
    19861 cccacgaagg agccgtcgtt ggtggtcttc tcgaacttca cgatgcggcc gagccccgcg
    19921 tcgaacggcg ttgtcgccgt ggacagttcg tgcccgtaca gcggcatgcc ggcctccagg
    19981 cggagcgtgt cacggcagct cagcccgcag ggcaccagcc ccaccggggc gcccgcctcg
    20041 gtgagcgcct cccagaccgc gacggcgtcg gcgggcgata cgaacagctc gaagccgtcc
    20101 tcaccggtgt agccggtacg ggcgatgagc gcctcgcgcc cggcgacggt gcccggcagg
    20161 cccgcgtagt acttcaggcc gtccaggtcg gcgtcggtga gcgccttgag gatgccggcg
    20221 gcctccgggc cctgcacggc gatcagcgcg taggcgtccc ggtcgtcgcg gaccgtcgcg
    20281 tcgaagcccg tgctgcgctc gtgcaacgcg tccagcacga cctgggagtt ggcggcgttc
    20341 gccacgacca tgtaccgctg ctcgcccgtg cggtagacga tcaggtcgtc gaggatgccg
    20401 ccctgaccgt cgcagatcat cgtgtagcgg gcgcggcccg ccttcagcgc cgagaggttg
    20461 cccaccaggg cgtagtccag cagctcgccc gcctgcgcgc cctcgacggc gatctcgccc
    20521 atgtgggaga ggtcgaacag ccccgcgcgg gtgcgcacgg cgacgtgctc gtcgcgctc
//
