LOCUS       NZ_FMHJ01000003        28067 bp    DNA     linear   CON 28-JUL-2024
DEFINITION  Streptomyces sp. WMMB 714, whole genome shotgun sequence.
ACCESSION   NZ_FMHJ01000003
VERSION     NZ_FMHJ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. WMMB 714
  ORGANISM  Streptomyces sp. WMMB 714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Varghese,Neha. and Submissions,Spin.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JUN-2016) DOE - JOINT GENOME INSTITUTE, 2800 Mitchell
            Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900090125.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 02:17:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,656
            CDSs (total)                      :: 5,578
            Genes (coding)                    :: 5,496
            CDSs (with protein)               :: 5,496
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 4 (16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 15 of 82
            Pseudo Genes (incomplete)         :: 72 of 82
            Pseudo Genes (internal stop)      :: 4 of 82
            Pseudo Genes (multiple problems)  :: 8 of 82
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 490569
            Orig. end                         :: 518636
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FMHJ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28067
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..28067
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28067
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18067](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18067)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1763..3262)
                     /locus_tag="H181DRAFT_RS07500"
                     /old_locus_tag="H181DRAFT_01513"
     CDS             complement(1763..3262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531550.1"
                     /locus_tag="H181DRAFT_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01513"
                     /product="thioester domain-containing protein"
                     /protein_id="WP_078895554.1"
                     /transl_table=11
                     /translation="MSFVRTAVTVVGGCATARRRRLLAAALFVPALLAGGLTAAATPAA
                     AGQAAPGEQPTWRGGALATLQGLETHGEAVVREDGEELTTSAGLFEMAVDGGGTLQTYG
                     TDVDSATQDQARYGETDWDQTSLHGNRNAGKILWILRHSYPQVNDLQALAKSSGAGKLT
                     PETAAAGTQVAIWRYSDAGGDVEVEAVDPAAEKLADHLHRKARTLAEPRASLSLDSAGV
                     AEKAKGRFGPLKVRTGAPSAAIAPASRSALRDVRVVGDGGRSAASVRDGGRLYLDVPSE
                     RRTGTASLTVQAATKVPVGRAFAGVGGQAGSQTQILAGSSRSTVSATADVSWDEHGVIP
                     AVGAVKDCRESGVRLTVTNSGDRPFRFRAAGEAHTVPAKRSKKITVPVGEDQAYRIPVS
                     APGVRKAFTGVLDCVTRSEAARPDMSGMTTQSQPATVGGGGSGGSAQDGGDLAETGASN
                     TPVLVGVAVGLVVVGAVAVLAVRRRGPEEAGEPGEAGQHTS"
     CDS             3261..3353
                     /gene="allorf_493830_493922"
                     /locus_tag="allorf_493830_493922"
                     /protein_id="allorf_493830_493922"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDFPSGRDGHDIGGHSVTGGRGRSCLAAQH"
     CDS_motif       3261..3320
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDFPSGRDGHDIGGHSVTGG"
                     /locus_tag="allorf_493830_493922_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3321..3353
                     /prepeptide="core"
                     /locus_tag="allorf_493830_493922_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.10"
                     /molecular_weight="1080.2"
                     /monoisotopic_mass="1079.6"
                     /core_sequence="RGRSCLAAQH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDFPSGRDGHDIGGHSVTGG"
                     /leader_location="[3260:3320](+)"
     misc_feature    3417..3430
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    3432..3447
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.12"
                     /tool="antismash"
     misc_feature    3435..3448
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.88"
                     /tool="antismash"
     gene            complement(3472..3948)
                     /locus_tag="H181DRAFT_RS07505"
                     /old_locus_tag="H181DRAFT_01514"
     CDS             complement(3472..3948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469026.1"
                     /locus_tag="H181DRAFT_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01514"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_045863564.1"
                     /transl_table=11
                     /translation="MNESQVTVVGNVATPVEFRRSAAGLPTARFRLASTVRRYDQRSGG
                     WADAFTNFYTVWAWRSLAANLASSVTVGEPLVVTGQLRIRQTERDGRQFASADLTATAV
                     GHDLSRGTSAFVRTPSRSGPRAGPGRNAEAPGGSSGAVTGGDVEAVIPRQGAAP"
     gene            complement(4123..6423)
                     /locus_tag="H181DRAFT_RS07510"
                     /old_locus_tag="H181DRAFT_01515"
     CDS             complement(4123..6423)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432791.1"
                     /locus_tag="H181DRAFT_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01515"
                     /product="GTPase"
                     /protein_id="WP_052708489.1"
                     /transl_table=11
                     /translation="MSTTDVRIDGSSEEKQAAPDAAAGSDGPTASGENRERQAAAAEGD
                     AAAEPGEGTAADGEAGAWDDGLIARRAHAASAPGERPAWSRAAALWGTDPDPEPPDSGG
                     HGVTAAPGRQIPGWSSDEASPVQPYEDFEGHEEYAQRAHGAGPRGAETSLSQRLAALSR
                     LLDLSRSRIPSGVLAEAQRVLDAAGARKQLPSAYTTVAIAGATGSGKSSLFNALAGTRL
                     SQAGMRRPTTATPVACSWEVPGAGPADGLLDRLAIPQSTRRLMRPESDWRGRIDDSARH
                     ELEGLVLIDLPDHDSAADGHRAQVDRLLRLVDAVVWVVDPEKYADAVLHERYLRPLAGY
                     AEVTFIVLNQTDRLPGEAKDAVLNDLRRLLDEDGMALGDHGEPGARVLATSALGGEGVD
                     ELRTDLAQFVARRRAAGLRLNADLDGVVGRLRAVYVPPGHVPAAASADALSGLTEEVRD
                     DFADRLARAAGAVTAGQAAERAWLRLADRACGTPWARLQHWYDDRRSAKEEPVAAELGD
                     AGAESAEAEAYAFSEAGEQAGREGAGGELPGAPAASAAAPPAGDRLPRVSRPAVAHAVR
                     TVVEQAGAGLPEAWHRSVRDAAWRGAAGLPEALDRALREDDAPEGAADGSERDGQGDGG
                     TARGGRARAAALRRPAWWALAFLGQLVLLLLQLVGAGWVAATALGAGVGEEWMGVALLL
                     GGVLGGSLLSWGCRFAARGPAAAYGQREEWRLRRLVASCGQVRVLEPVAAELLRYREVR
                     EQYVIVSGEAGRL"
     misc_feature    6404..6417
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            complement(6429..8198)
                     /locus_tag="H181DRAFT_RS07515"
                     /old_locus_tag="H181DRAFT_01516"
     CDS             complement(6429..8198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605571.1"
                     /locus_tag="H181DRAFT_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01516"
                     /product="dynamin family protein"
                     /protein_id="WP_074467756.1"
                     /transl_table=11
                     /translation="MAILNVRPELLDALTALREGVAAARFPLPLPGAERARRSRDELLA
                     QLDDYLMPRLRVPDAPLLAVVGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRTPVLVCH
                     PDDREWFSGRRILPRLERVRVPRQDAAQGQFGVGARGDSADDELLGVEETDAEDDGRRP
                     LRIETDSALPPGLALLDAPDIDSLVARNRDLAAELLCAADIWVLVTTAARYADAVPWNL
                     LRTAKEYDVTLVTVLDRVPHQIAPDVARQYGALMIREGLADVPRFTVPELPESAGGSGL
                     LPATAVAGLRNWLAQRALDPAARAVAGRRTAVGALASLRPRVASLANASAAQHAAATRL
                     TGHVEDAFEEARVRVRRHIAVGELLAGDADALWRGFPVDSRGEEVLDAFEEGLTTLLAS
                     AVAAADERIAESWRREPAVPGGESAEATGDLPADRGRGLPEGLRGSDGRGRMNLLVRRW
                     RRCMEELADEEARAVDHGFGRDAEEAAALLATALVGGGHAAGAYRSLAAAFGEVSARKL
                     RECGVRLLATYVERALYGERDRRLAPLEALETAPGPQVDLIAALSVLRKAEAAVLPGPG
                     ARKLTESQSQTER"
     misc_feature    complement(8209..8225)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.93"
                     /tool="antismash"
     CDS             complement(8404..8520)
                     /gene="allorf_498973_499089"
                     /locus_tag="allorf_498973_499089"
                     /protein_id="allorf_498973_499089"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRACLRVTVAWSRIGGPVAGAVCFTSATPCGGSVKRSR"
     CDS_motif       complement(8458..8520)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRACLRVTVAWSRIGGPVAGA"
                     /locus_tag="allorf_498973_499089_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8404..8457)
                     /prepeptide="core"
                     /locus_tag="allorf_498973_499089_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.40"
                     /molecular_weight="1665.9"
                     /monoisotopic_mass="1664.9"
                     /core_sequence="VCFTSATPCGGSVKRSR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRACLRVTVAWSRIGGPVAGA"
                     /leader_location="[8457:8520](-)"
                     /alternative_weights="1683.9"
                     /alternative_weights="1702.0"
                     /alternative_weights="1720.0"
     tRNA            8537..8609
                     /anticodon=(pos:499139..499141,aa:Arg,seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="H181DRAFT_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="H181DRAFT_01517"
                     /product="tRNA-Arg"
     gene            8537..8609
                     /locus_tag="H181DRAFT_RS07520"
                     /old_locus_tag="H181DRAFT_01517"
     misc_feature    8609..8620
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(8810..9769)
                     /locus_tag="H181DRAFT_RS07525"
                     /old_locus_tag="H181DRAFT_01518"
     CDS             complement(8810..9769)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991788.1"
                     /locus_tag="H181DRAFT_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01518"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_175439724.1"
                     /transl_table=11
                     /translation="MRLSILLPFGPVRPEQVVPFANLVHWTCAHRLWQGHGMLLDSHHL
                     INWLAGIGIRVPSGFGVSLMPLRSPYQAALEARSVALNTGHSVVAGFGPGGVAAQRSFM
                     GKPYASPLAASREYVSTVRGLLSGEVTEVHGDHYSSVSRLVEFKPAPVSVGLGVLREKM
                     AALAGEIADVAITWLGSAHYLHETLMPAMEDGARERRSGDPAKVTAIVPVALSGPDRKV
                     ADLAAAACGQHIQAPHYKDALRKAGVEITGDGSSGDAMKLVDGGVFLYGTAEEIHERLD
                     EYRKIGVDEVVLNATGVGNVAGPRAAATDLLAILDAAS"
     gene            complement(9840..10004)
                     /locus_tag="H181DRAFT_RS29130"
                     /old_locus_tag="H181DRAFT_01519"
     CDS             complement(9840..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS29130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_01519"
                     /product="DUF945 domain-containing protein"
                     /protein_id="WP_139131674.1"
                     /transl_table=11
                     /translation="MKKSRGTWGVVVAIGGAIAITSAYSGNTVLAGVVGVLTVVVAAAT
                     FMKFDRKQS"
     gene            complement(10001..12850)
                     /gene="lanM"
                     /locus_tag="H181DRAFT_RS07530"
                     /old_locus_tag="H181DRAFT_01520"
     CDS             complement(10001..12850)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="H181DRAFT_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01520"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_158715420.1"
                     /sec_met_domain="DUF4135 (E-value: 1.6e-61, bitscore:
                     203.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-23, bitscore:
                     78.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPDVSIPAFLPFYAHLAPRSAVEDALRDLAAPVTAPEHLEEVL
                     DQVWSGMLTAVEGQSFRTLIGEFHAFREDHGLPMDAEGDKALQAFRAHLGSDANCRELT
                     GRYPVLRQRLATIRRNLLDAYTDLFAACAADRAELKAAGLLPAGDSEALIEKIFLTGSD
                     PHNDNRQVIQLRLTGGTRLVFKPRALVSDRFVKDLYDAADPYLEHSLRDCIPISVSTDT
                     HGWQQHVASAPMDSPDQPARYFYRFGALCAVFGTLGASDMHDENLLACGETPSVIDTET
                     MLRADAGVDNDSLPHVLVNHMKLSVVSTMLVPVVNPTSPIDVVMAGVGVAGDQKSKLKR
                     AAVRDGTTDRISVTWEPVTYKHHGNVPRLGDERLSAPDYFSDILAGYSDGLAFVRDGGI
                     SKVVDAYPGMPVRSLMRSTMVYGRFLDASTHPDYLREPAEAARLFGLLARMPDYLSPEA
                     ADYVAEEERASLSTGNVPYFMTRADSKELSTLRTGFPGVYKTSPLDMARRGIAMNSERS
                     DLYHHFLLEECFSEVVGEDRPEGLSSESLFGRPVLDSARPGAWWPEIARRIDEIGVRFE
                     GPEGTETGWVCGIGPERNVSTITPGNFVSFHDSGGIVTFLERASRHDSELRSVHAGADR
                     GLRSLLAKYGDLLMQTPESVFTGAASMLLTRPADVDREWLAKVFERIEERAISNELEND
                     LANGPAGLLMVLLSRIGESGVGGESVLCDEKQLGKLRDLTLEHLSADRTAKWFDVAHGE
                     LGLRWACSRLGRVLDDPALVEQSADWLVSRSSSGEQTPYAGWCNGAAGQLLTSAEILGA
                     AGRTDWLKGARLQSLVDKATALPEGRAFDLSVCHGSSGVVQSLVAAGRLLGEKSLFTRA
                     HEYQELVLDRIRRTGFYTGAGGRTSLLGYMFGWSGIGDTDVILQSSGTSPGKSVGDSHL
                     PVALSSGVLDRRTAAGGSQ"
     gene            complement(12853..15039)
                     /locus_tag="H181DRAFT_RS07535"
                     /old_locus_tag="H181DRAFT_01521"
     CDS             complement(12853..15039)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991785.1"
                     /locus_tag="H181DRAFT_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01521"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_045863410.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.9e-28, bitscore:
                     93.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTLRSRKHARRVPTLTQVTQTECGLCCSVALLRYYGRAEDLSS
                     ARAVMDAGRDGLSAGQLARYLRTRGMDAKLFRAKSVSALEKFTSPVILYWEEYHFVVLE
                     KFDGQKATVMDPAVGRRRLSREELEEGFSGIVVSADVGPDFEKTRQKPMTEWRDIPLFA
                     EGSRKRIALVGLLSFSGYGAVLGIPMLTEWAVDQQARWKGLDDLGTVIAVVLGVAAAYL
                     ALHVVRVMVLSSVVAMLGKHLMTHTFSKMLSLPYRFFTVRQPGELLFRLNSVNMIRDLL
                     SSRVAQGILDVGTLLCVTGYLFYVEWRLGLMAVVLFLLNAFYLARTRPKLMEFVDSEIS
                     QLSKSQSTQLDAIVSIPTIKMGGYADEFLESWGKVYGSSLEAMKDRMRMQQGRISGVTT
                     TTQMFGPMILLLSSLYFVSHGYISLGAAIAVQAVSATYFSLSTSVFSTYTEFTEASRYM
                     ARLSDIVKSEPEDPGGTLTGLLSTSIQLEDVSFQYTKHSDLVIRNVSLDIPAGSRVALV
                     GASGSGKSTLGRIICGLYEPTRGNVRFGDVDTRHYDKNALRRQIGYIPQEIHLHNRTIL
                     ENLTLGQDIPADKVREYCAGVGILDFLEDLPMGLKTLVSEMGANFSGGQRQRLAIVRAL
                     LQNPPILVLDEATSALDTVNERRVGEIIEHIGATQVIIAHRLATIKSADHIYVLDNGRV
                     VEQGSHTQLLHGGAVYTDLYADRSPDLDVVVGGE"
     gene            complement(15041..18067)
                     /gene="lanM"
                     /locus_tag="H181DRAFT_RS07540"
                     /old_locus_tag="H181DRAFT_01522"
     CDS             complement(15041..18067)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179558.1"
                     /locus_tag="H181DRAFT_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01522"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_045863411.1"
                     /sec_met_domain="DUF4135 (E-value: 4e-72, bitscore: 238.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-47, bitscore:
                     156.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPAKYYPEFDSAEVEETIVPLSQFDDQFTGVLRAGGESADERP
                     SPGEGTRATVREWLGRPEQYPFQSIIRGVAAGVAGTDPVAPFGKLFSDPDAMLVQLLER
                     TESRVREVYSRPLVAAINHAREEGRLVGETSEERYRYFVDQARLTSFEEVSGLSFPVLR
                     DITRILLANGAESVAELCRRLVADREAIAGTFGIEVPDRIVSCGFSEGDAHNHGRSVSV
                     LEFESGKKLVYKPRDVSCEAAYEHIATELNKEIGTSLAAAQVLERNHYGYVEFIETEDV
                     SDMSGEFMRASGELAAVLYLLNARDMHFENILPTRRGPVPIDLETILHPARVHEGPTPE
                     AVGNAYETIGQSIYGIGILPLVMVGKGEDAGHVDLGFLGDQGRGSSPFKSIFFENPYTD
                     RISLVIRAQEAQGRRTVVNSLGEDEVRVLGDRMAEGFSRVFRTMMASQDSWAELLRKAA
                     SGMRVRYVHNPTALYAQTLRMTSSAGALDDVSPYIALLKRIAIASKTSSRQIVRSEIRQ
                     LAERDIPYFTVSATGVALEDGDGREVGAFFDESPVDRALAKTAHMTETDLREQLRLVYS
                     AFSSRFPDNHLAASGTSDGGAFHAPSDRGTAGDSHGELVELVERLAGNLVETSLPDKFA
                     HLPRTWIGPLASAAANRPWPPGVLGYDLYTGRVGPALALAAAGRFLDRGEYRDLAGQIF
                     STMADILAGHRYERRSIQQAGFGGYTGMAGILFALATTGRLLENDEWVEAAQGALPLVL
                     DQMRDIDPRALPIDVVNGVAGVMGCVTAIGGPHADGSLAALTGMLTDAVRDGHGAVFAQ
                     SGFAHGVSGLLHALSGALPRVPAGQQDVVRATLKDLVGRLQEFYDREQGNWFSNAATPW
                     SFSTGWCHGATGIALALSSYGQVAKDDVVNCMRDVAIGNLVRHGFGRNLTWCHGDLGNH
                     DVLAKLAADDEGLREEVAKIEQRWLQPDVLIRKTNDNQSRYAHTNSLMVGTAGIVLHLV
                     NRLDPSVHISPVTLTFESR"
     gene            complement(18198..18350)
                     /locus_tag="H181DRAFT_RS29345"
                     /old_locus_tag="H181DRAFT_01523"
     CDS             complement(18198..18350)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179559.1"
                     /locus_tag="H181DRAFT_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01523"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_175439725.1"
                     /transl_table=11
                     /translation="MSDDILGGYDEAELVELSDADAYGGTAWVCATVTLATAAICPTTK
                     CTSQC"
     CDS_motif       complement(18327..18350)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDDILGG"
                     /locus_tag="H181DRAFT_RS29345_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18198..18326)
                     /prepeptide="core"
                     /locus_tag="H181DRAFT_RS29345_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.10"
                     /molecular_weight="4181.6"
                     /monoisotopic_mass="4178.9"
                     /core_sequence="YDEAELVELSDADAYGGTAWVCATVTLATAAICPTTKCTSQC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDDILGG"
                     /leader_location="[18326:18350](-)"
                     /alternative_weights="4199.6"
                     /alternative_weights="4217.7"
                     /alternative_weights="4235.7"
                     /alternative_weights="4253.7"
                     /alternative_weights="4271.7"
     misc_feature    complement(18369..18387)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(18382..18546)
                     /locus_tag="H181DRAFT_RS07545"
                     /old_locus_tag="H181DRAFT_01524"
     CDS             complement(18382..18546)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237622.1"
                     /locus_tag="H181DRAFT_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01524"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_229711746.1"
                     /sec_met_domain="mature_ha (E-value: 1.1e-12, bitscore:
                     42.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKGDVSLVEEIAEQDFDGVAYGACTTNTFSLSDVLGNTGGWCTL
                     TVECQPNCN"
     CDS_motif       complement(18475..18546)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MYKGDVSLVEEIAEQDFDGVAYGA"
                     /locus_tag="H181DRAFT_RS07545_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18382..18474)
                     /prepeptide="core"
                     /locus_tag="H181DRAFT_RS07545_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="3035.3"
                     /monoisotopic_mass="3033.4"
                     /core_sequence="CTTNTFSLSDVLGNTGGWCTLTVECQPNCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYKGDVSLVEEIAEQDFDGVAYGA"
                     /leader_location="[18474:18546](-)"
                     /alternative_weights="3053.4"
                     /alternative_weights="3071.4"
                     /alternative_weights="3089.4"
                     /alternative_weights="3107.4"
     misc_feature    complement(18702..18717)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(18841..18855)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.17"
                     /tool="antismash"
     misc_feature    18842..18853
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.96"
                     /tool="antismash"
     gene            complement(19184..19957)
                     /locus_tag="H181DRAFT_RS07550"
                     /old_locus_tag="H181DRAFT_01525"
     CDS             complement(19184..19957)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130179.1"
                     /locus_tag="H181DRAFT_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01525"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_045863413.1"
                     /transl_table=11
                     /translation="MSDTGAAVAFEWTKIRTLRSTVWSLALFSAASVAVALLFGYVMRG
                     TYADLDAQAQARFDPVASGFSGMKLGMIALVVFGVLTVSSEYSTGSIRSSLAAVPRRGV
                     LYAAKLLTGTATALVVSAVVVTLSFFATQMMLGSPASVSLSDDGVLRALIGGVLYMTLI
                     CAFSMGLASVLRSSALTMGILVPLFFMISTILNSIPGVQKVAQFLPDLAGGLILRSKEP
                     HGDGVLTAWTGMAVLAAWAVLAVAAGYYAMRRRDA"
     gene            complement(19960..20874)
                     /locus_tag="H181DRAFT_RS07555"
                     /old_locus_tag="H181DRAFT_01526"
     CDS             complement(19960..20874)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173620.1"
                     /locus_tag="H181DRAFT_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01526"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_045863414.1"
                     /transl_table=11
                     /translation="MIEVQKLTKRYGETLAVDGLSFQVRPGRVTGFLGPNGAGKSTTMR
                     AMIGLDRPTSGQVLIDGRRYEQIAQPLRKVGALLEAKALHGGRTAYGHLLGLARSNRIP
                     EARVGEVLETVGLSATAKKRAGGFSLGMAQRLGVAAALLGDPEVLLFDEPVNGLDPEGI
                     LWIRELMKKLAGEGRTVFVSSHLMSEMALTAEHLIVIGQGRLLADTTVEDFIARNSRSY
                     IHIRTPEPERMRDVLAGEGIRTDNGPEGVLEALGTTLETVGKLASKHQVTVYEISPRTA
                     SLEEAFMQLTADAVDFRADLEVR"
     CDS             20966..21097
                     /gene="allorf_511535_511666"
                     /locus_tag="allorf_511535_511666"
                     /protein_id="allorf_511535_511666"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKAAERISESAACWRRTSSHGLHVRGTVSRDVPILTIPGDLYD"
     CDS_motif       20966..21001
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKAAERISESAA"
                     /locus_tag="allorf_511535_511666_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21002..21097
                     /prepeptide="core"
                     /locus_tag="allorf_511535_511666_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="3399.8"
                     /monoisotopic_mass="3397.8"
                     /core_sequence="CWRRTSSHGLHVRGTVSRDVPILTIPGDLYD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKAAERISESAA"
                     /leader_location="[20965:21001](+)"
                     /alternative_weights="3417.8"
                     /alternative_weights="3435.9"
                     /alternative_weights="3453.9"
                     /alternative_weights="3471.9"
                     /alternative_weights="3489.9"
     CDS             complement(21050..21262)
                     /gene="allorf_511619_511831"
                     /locus_tag="allorf_511619_511831"
                     /protein_id="allorf_511619_511831"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAPSWARRRAVRVICSAVRVRAPGADGARPPGERAGLCADGQGRT
                     GSPTEPVVPRSVVQIAWNRQDRHVP"
     CDS_motif       complement(21188..21262)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAPSWARRRAVRVICSAVRVRAPGA"
                     /locus_tag="allorf_511619_511831_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21050..21187)
                     /prepeptide="core"
                     /locus_tag="allorf_511619_511831_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="4719.2"
                     /monoisotopic_mass="4716.4"
                     /core_sequence="DGARPPGERAGLCADGQGRTGSPTEPVVPRSVVQIAWNRQDRH
                     VP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAPSWARRRAVRVICSAVRVRAPGA"
                     /leader_location="[21187:21262](-)"
                     /alternative_weights="4737.2"
                     /alternative_weights="4755.2"
                     /alternative_weights="4773.2"
     gene            21419..22078
                     /locus_tag="H181DRAFT_RS07560"
                     /old_locus_tag="H181DRAFT_01527"
     CDS             21419..22078
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H181DRAFT_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H181DRAFT_01527"
                     /product="hypothetical protein"
                     /protein_id="WP_045863415.1"
                     /transl_table=11
                     /translation="MSDSPKAALAASVAAGYLLGRSRKAKLAIAVATFMVSGRLQSKPQ
                     ELLASGLGRLGDSPQFAQLADQVRDELLTVGREALKTAVDRRLGTFADSLAERTSSLNG
                     LGGVLGGVQGGDEDNGGDDGDDGERDEAADEREEPGGEPEEEEESSGRGGEGRRRPPRE
                     RRDEQAAAPRKRAKKTAGKPAAKKAPAKKAPPKKAAKKTGGRKTASNSPAEQRRRR"
     gene            22084..23100
                     /locus_tag="H181DRAFT_RS07565"
                     /old_locus_tag="H181DRAFT_01528"
     CDS             22084..23100
                     /NRPS_PKS="Domain: Polyketide_cyc (119-241). E-value:
                     1.7e-14. Score: 46.1. Matches aSDomain:
                     nrpspksdomains_H181DRAFT_RS07565_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524460.1"
                     /locus_tag="H181DRAFT_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01528"
                     /product="SRPBCC family protein"
                     /protein_id="WP_045863416.1"
                     /transl_table=11
                     /translation="MPQKDSGKDAANDGGSGLDRVREELSNYLTAKTSNLVSSAGGKVS
                     GLAQKVAEGGAPGGGDLPKMGAKLLKGESPAKAVGGQMVKKVKDKTVGKVQELFGGGGE
                     AGDKKTTNIVEVLDIGLPLRRVYDHWTEFEEFSSFMKGVVEASRGDDETTSEWTGKVGP
                     SKRSWKAEVLEQVPDNRIVWKSSGEATTHGSISFHELAPNLTRIVVVVEYTPGGFLEKT
                     ANLWRAQGRRLRLDLKHFLRYVSLGVQEVPEGWRGEIREGEVVRSHEDVLAEDEEDRGD
                     GGGEERDEGDAEEEGNGEDFEDEDDEVDEDEEDRNGEDFEDEEDEYEDEDEREYETR"
     aSDomain        22441..22806
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H181DRAFT_RS07565_Polyketide_cyc
                     .1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="1.70E-14"
                     /label="H181DRAFT_RS07565_Polyketide_cyc.1"
                     /locus_tag="H181DRAFT_RS07565"
                     /protein_end="241"
                     /protein_start="119"
                     /score="46.1"
                     /tool="antismash"
                     /translation="GLPLRRVYDHWTEFEEFSSFMKGVVEASRGDDETTSEWTGKVGPS
                     KRSWKAEVLEQVPDNRIVWKSSGEATTHGSISFHELAPNLTRIVVVVEYTPGGFLEKTA
                     NLWRAQGRRLRLDLKHFL"
     gene            complement(23270..23953)
                     /locus_tag="H181DRAFT_RS07570"
                     /old_locus_tag="H181DRAFT_01529"
     CDS             complement(23270..23953)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984216.1"
                     /locus_tag="H181DRAFT_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01529"
                     /product="hypothetical protein"
                     /protein_id="WP_107068704.1"
                     /transl_table=11
                     /translation="MSTRHQPARSLRVVVTGIVAAAALLAAGAASATPLSGAAGTAAAE
                     STTVTPAGDEYAAKLTGEATFTAGSVTVSCTVSEATGRIPAAPGNHNDAGPVESGINPP
                     TYDSCTASLPGVDATVETTGDWTVSMQNGAPATAGLTMPTAGFVLKTSGLAECTVTAAP
                     TEAATATGTWANGSPSTLTFDEAAVPVTVEGGFGCPTSATSSAFSATYEITDTTDPGAD
                     VTVTS"
     misc_feature    complement(23921..23923)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(24018..24644)
                     /locus_tag="H181DRAFT_RS29820"
                     /old_locus_tag="H181DRAFT_01530"
     CDS             complement(24018..24644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004952551.1"
                     /locus_tag="H181DRAFT_RS29820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01530"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_254666739.1"
                     /transl_table=11
                     /translation="MLLIWRRWRGWRRGRPFWGGLLTVLAGTEIAVIPLAPLKVMLHQG
                     TAGLPTVVLGLVMVVLGFSAWFGPQYRGLAGVLTVLLATAALVLSNLGGFVIGTLLGVV
                     GGALIFAWRPVPAGPPPDGQTEAEPADGTAAHAGTPSGAAADGGRAGGTLAGTARGASA
                     GTAADASKEDTLSSLASAFSVPQQPPPPESPGTPSGNSKTSRSPE"
     gene            complement(24635..25255)
                     /locus_tag="H181DRAFT_RS07580"
                     /old_locus_tag="H181DRAFT_01531"
     CDS             complement(24635..25255)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093340.1"
                     /locus_tag="H181DRAFT_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01531"
                     /product="DUF6230 family protein"
                     /protein_id="WP_045863418.1"
                     /transl_table=11
                     /translation="MKDAHGRPLTGRTSWRKFAVLCVPGFAATAALAIALANGALAASF
                     AVSGQQFKVSAKSLDGDGFVQYGSIDKNARGELIPVAVTGIKTAEMRDLCQSVVTKLPV
                     IGSISLNLTAGTGSKPVEATDLFVDATQLSGDAGFNKIEIGRDASTLDKGPKGGQGLQD
                     LFGQQADDVHISSLKQTAWATNAGKFKLSGLSMKVNKGTKECF"
     CDS             25624..25779
                     /gene="allorf_516193_516348"
                     /locus_tag="allorf_516193_516348"
                     /protein_id="allorf_516193_516348"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAESSSSDTGRECAEGPAEAGSGEERSRGRGKRLRNALCGGWPGR
                     RAPQGS"
     CDS_motif       25624..25689
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAESSSSDTGRECAEGPAEAGS"
                     /locus_tag="allorf_516193_516348_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       25690..25779
                     /prepeptide="core"
                     /locus_tag="allorf_516193_516348_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="3129.5"
                     /monoisotopic_mass="3127.7"
                     /core_sequence="GEERSRGRGKRLRNALCGGWPGRRAPQGS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAESSSSDTGRECAEGPAEAGS"
                     /leader_location="[25623:25689](+)"
                     /alternative_weights="3147.5"
     misc_feature    complement(25843..25854)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     gene            25903..26997
                     /locus_tag="H181DRAFT_RS07585"
                     /old_locus_tag="H181DRAFT_01532"
     CDS             25903..26997
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948475.1"
                     /locus_tag="H181DRAFT_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H181DRAFT_01532"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_045863419.1"
                     /transl_table=11
                     /translation="MSAPTVYDVAGRAGVSIATVSRVYRAPDSVRVGTRERVLEAAREL
                     GYVPSGNARGLASRNTRVLGLCFPDYADPDAEDPDGDYGDAELMLYSDEIIRGMERAAR
                     RHGYALLIAASLAEGPKSLVADVAGRVDGFAVLARTVPTEELEVISRRLPVVMLAGPRE
                     DAPLDHLDHVEVANFDGELALTRHLIADHGITRLAFVGSTEDSPDGEARFRGFQAAHLE
                     AGLPVPERPDVRTRLTQAEGRQAVAELLDSRSELPGGVVFANDQMAVGALSELNRRGVR
                     VPEDLAVAGFDGIPLGRLVTPALTTVRQPMRRLGEEAVDLLVARLEDRDREPESRVLPV
                     SVIRRSSCGCANGHDAVPDTASVT"
     misc_feature    complement(27125..27142)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.96"
                     /tool="antismash"
     misc_feature    complement(27797..27812)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.07"
                     /tool="antismash"
ORIGIN
        1 acgagccgcg tccggaccca gcctctcgat cttgttcttc tcgtacgact cgaagttgcc
       61 ctcgaaccag aaccacttgg actcgccctc gtaggcaagg atgtgcgtgg ccacgcggtc
      121 gaggaaccag cggtcgtggg agacgaccac ggcgcagccc gggaagtcca gcagcgcgtt
      181 ctccagcgac gagagcgtct cgacgtcgag gtcgttggtc ggttcgtcga gcagcagcag
      241 gttgccgccc tgcttcaggg tgagggccag gttgagcctg ttgcgctcac cgccggagag
      301 cacgccggcc ggcttctgct ggtccggtcc cttgaaaccg aacgcggaca cgtaggcccg
      361 ggagggcatc tcgacctggc cgacgttgat gtagtcgagc tcgtcggaga cgacggccca
      421 cagggtcttc ttggagtcga tgttctcgcg gctctggtcg acgtaggaga tcttgaccgt
      481 gtcgccgacc ttgatgctgc ccgcgtcggg ctcctcgatc ccctggatca tcttgaacag
      541 cgtggtcttg cccgcgccgt tggggccgat cacgccgacg atgccgttgc gcggcaggga
      601 gaaggagagg tcgtcgatga ggaccttgtc gccgaacgcc ttgctgaggt tctccacctc
      661 cacgacgatg ttgcccagtc gcgggcccgg cgggatctgg atctcctcga agtccagctt
      721 ccgggtcttc tccgcctcgg cggccatctc ctcgtaacgc gtcagccgcg cccgggactt
      781 ggcctgacgg cccttggcgt tggagcggac ccactccagt tcgtccttga gccgcttctg
      841 acgcttggcg tccttctgac cctcgacctt cagacgcgac tgcttcttct ccaggtacgt
      901 ggagtagttg ccctcgtagc cgatggcacg gccgcggtcc agctccatga tccagccggc
      961 gacgttgtcc aggaagtacc tgtcgtgagt gatcgcgacg acggtgccgg ggtactgcgc
     1021 caggtgctgc tccagccact ggacggactc ggcgtccagg tggttggtcg gctcgtcgag
     1081 gaggagcagg tcgggctgct ccagcagcag cttgcagagg gcgacgcggc gcttctcacc
     1141 gccggacagg ttcgtgaccg gccagtcccc gggcgggcag cccagcgcgt ccatggcctg
     1201 ctcgagctgc gactccaggt cccaggcgtt ggagtggtcc agctgctcct gcagcttgcc
     1261 catctcctcc atcagctcgt cggtgtactc ggtcgccatc tgctcggcga tctcgttgaa
     1321 ccggtccagc ttgcccttgg tctccgcgac gccggcctcg acgttctcca ggaccgtctt
     1381 cgactcgtcc agcggcggct cctgcagcag gatgccgacg ctgtagcccg gggagagctg
     1441 ggcgtctccg ttggagggct ggtcgagccc ggccatgatg cgcagcaccg tggacttacc
     1501 ggcgccgttc ggccccacga caccgatctt cgcgcccggc aggaagctca aggtgacgtc
     1561 gtcgaggatc accttgtcgc catgcgcctt gcgcgccttg cgaagggtgt agatgtactc
     1621 agccaagagg aaccgtccgg caatcagtag gtgtcgaagt gcggccgcgc cgcatgggca
     1681 gacagcaccc atcttgccgc acgtcaccgc tcagcccgaa acggggcggt cgcggccccc
     1741 acgccgcggt gtgaactgct cgctacgaag tgtgctgtcc ggcttccccc ggctctccgg
     1801 cctcttccgg cccgcggcgg cgcaccgcga ggaccgcgac ggcacccacg acgacgagtc
     1861 ccaccgcgac gccgacgagc accggggtgt tgctcgcacc cgtctccgcc aggtccccgc
     1921 cgtcctgggc ggagccgccc gagccgcccc cgccgacagt ggccggctgg gactgcgtcg
     1981 tcatcccgct catgtccggc ctggcggcct cgctcctcgt gacgcagtcc agtacgccag
     2041 tgaaggcctt ccgcacgccc ggtgcgctga cggggatgcg gtacgcctgg tcctcgccca
     2101 cgggcaccgt gatcttcttg ctgcgcttcg ccggcacagt gtgggcctcg cccgcggcgc
     2161 ggaagcggaa cggccggtca ccggagttgg tcacggtgag gcgcacgccg ctctcccggc
     2221 agtccttcac cgcgccgacg gcgggtatca cgccgtgctc gtcccagctg acgtcggccg
     2281 tcgccgagac cgtggaccgg ctggagcccg cgagtatctg cgtctggctg ccggcctgcc
     2341 ctcccactcc tgcgaaggcc cggccgaccg ggaccttcgt agcggcctgc acggtcagcg
     2401 aggccgtccc cgtccggcgc tccgacggca cgtcgaggta cagccgcccg ccgtcccgga
     2461 cggaggccgc gctcctgccg ccgtcaccca cgacccgaac gtcgcggagg gcggagcggg
     2521 acgccggggc gatcgccgcg ctcggtgcgc cggtacgcac cttcagcgga ccgaaccggc
     2581 ccttcgcctt ctcggcgacc ccggcggagt cgagggagag tgaggccctg ggctcggcca
     2641 gcgtgcgggc cttgcggtgc aggtggtcgg cgagcttctc cgcggcgggg tcgacggcct
     2701 cgacctcgac gtctcccccg gcgtccgagt acctccagat ggccacctgg gtgcccgccg
     2761 ccgccgtctc cggggtgagc ttgcccgccc cggacgattt cgccagcgcc tgcagatcgt
     2821 tgacctgcgg gtacgagtgc cggagtatcc agaggatctt ccccgcgttc cggttgccgt
     2881 gcagcgaggt ctggtcccag tccgtctcgc cgtaccgagc ctggtcctgc gtggcgctgt
     2941 cgacgtccgt gccgtacgtc tgcagggttc cgccgccgtc gacggccatc tcgaacaggc
     3001 cggcgctcgt ggtcagttcc tcgccgtcct cgcggacgac cgcctcaccg tgcgtctcca
     3061 gcccttgcag cgtggccagg gcaccgcccc gccaggtggg ctgctccccg ggtgccgcct
     3121 gtcctgcggc tgcgggggtg gctgcagccg tcaggccgcc cgccagcagc gccggcacga
     3181 acagcgccgc ggccagcagc cgccgcctcc gcgcggtcgc gcatccgccc acgacagtca
     3241 cagcggtgcg gacaaagctc atggatttcc cctccgggcg agacggacac gacatcggcg
     3301 gtcactcggt gaccggtggt cggggacggt cttgtctcgc cgcacagcac tgaacccccg
     3361 tcagccatgc ggaggatcgt aaggagcggg cgcgacccgc ttcccctcga acgggtcgag
     3421 caagcgttct gatccacaat cgttatcagc gaatccggcg gaccgggacg atcacggcgc
     3481 ggcaccctga cgcggaatga ccgcctccac gtcgccgccg gtcacagctc cggaactccc
     3541 tccgggcgcc tccgcgttgc ggcccggacc agcacgcggg ccgctccgcg acggggtgcg
     3601 gacgaacgcc gacgtgcccc gggagagatc gtggcccacc gccgtggccg tcagatccgc
     3661 cgaggcgaac tgccgtccgt cccgctccgt ctgacggatc cgcaactgcc ctgtgacgac
     3721 gagtggttcc cccaccgtca ccgacgaagc gaggttggcg gccagcgatc tccaggccca
     3781 gacggtgtag aagttcgtga acgcgtccgc ccagcctccc gacctctggt cgtagcgccg
     3841 cacggtactg gccaggcgga accgggctgt cggcagcccc gcggccgacc tccggaactc
     3901 gaccggcgtc gcgacgttgc ccacgacagt cacctgcgac tcgttcacac gcaccccctg
     3961 atcccggcag cgccacccgc gccgctcacg gacctcagag tgcaccgatt tccgaaatcc
     4021 cgctcagagc tggggattac cgaatagttg tggacaaccc gctcacacct gagggggccg
     4081 gagcgcgcct cgacgccgct ccggccccct caggacggac ggttacagcc ggcccgcctc
     4141 gcccgacacg atcacgtact gctcgcgcac ctcccggtag cgcagcagct ccgcggccac
     4201 cggctccagc accctgacct gcccgcacga cgccacgagc cggcgcagcc gccactcctc
     4261 acgctgcccg tacgctgccg ccggcccccg cgccgcgaag cggcagcccc aggagagcag
     4321 cgaaccgccg agcacgcccc cgagcagcag ggcgaccccc atccactcct cgccgacacc
     4381 ggcgcccagc gctgtcgcgg ccacccatcc ggcaccgacg agctggagaa gcagcagcac
     4441 cagctgcccc aggaaggcca gcgcccacca ggccggacgg cgcagcgctg ccgcccgggc
     4501 gcgtccgccc cgcgcggtcc cgccgtcgcc ctgcccgtcc ctctccgagc cgtccgcggc
     4561 accctcgggg gcgtcgtcct cccgcagcgc cctgtccagg gcctccggca gccccgccgc
     4621 tccgcgccac gcggcgtccc gcacggagcg gtgccacgcc tcgggcagcc cggcgcccgc
     4681 ctgctcgacc actgtgcgaa cggcgtgggc gacagcaggc cgcgagaccc tgggcagtct
     4741 gtcgccggcc ggaggtgccg ccgcggaggc ggcgggcgcg ccgggcagct cgcctccggc
     4801 accttccctg ccggcctgct cgcccgcctc ggagaaggcg tacgcctcgg cctcggccga
     4861 ctcggctccc gcgtcgccga gttccgcggc gacgggctcc tccttggcgg agcggcggtc
     4921 gtcgtaccag tgctggaggc gggcccacgg cgtcccgcac gcgcggtcgg ccagccgcag
     4981 ccaggcgcgc tcggccgcct gccccgcggt gaccgcgccc gccgcgcggg ccagcctgtc
     5041 ggcgaagtcg tcgcggacct cctccgtcag cccggacagc gcgtccgctg aggccgccgc
     5101 cgggacgtgg ccgggaggca cgtacaccgc acgcagccgt cccacgacac cgtccaggtc
     5161 ggcgttgagc cggagtcccg cagcgcggcg ccgggcgacg aactgcgcga ggtccgtgcg
     5221 gagttcgtcg acgccctcgc ccccgagcgc ggaggtggcc agcacccgcg cgccgggctc
     5281 cccgtggtcg cccagcgcca tgccgtcctc gtcgagcagc cgccgcaggt cgttgagcac
     5341 cgcgtccttc gcctcgccgg ggaggcggtc ggtctggttg aggacgatga aggtcacctc
     5401 ggcgtacccg gcgagcgggc gcaggtaccg ctcgtgcagc acggcgtcgg cgtacttctc
     5461 ggggtcgacg acccacacca ccgcgtcgac gagccgcagc agccggtcca cctgtgcgcg
     5521 gtggccgtcc gcggcggagt cgtggtccgg gaggtcgatg aggacgagcc cctccagttc
     5581 gtggcgggcc gagtcgtcga tgcgtccccg ccagtccgac tcgggacgca tgagcctgcg
     5641 cgtcgactgc gggatcgcga gccggtcgag gaggccgtcg gccgggcccg cacccggcac
     5701 ctcccacgag caggcgacgg gtgtggcggt ggtggggcgg cgcatgcctg cctgcgaaag
     5761 ccgcgttccg gcaagggcgt tgaagaggga cgacttgccg ctgcccgtgg ctccggcgat
     5821 cgccacggtc gtgtacgcgc tcgggagctg cttgcgggcg cccgcggcgt ccaggacgcg
     5881 ctgggcctcc gcgaggacgc ccgaggggat ccgggagcgg gagaggtcga ggagcctgct
     5941 cagcgcggcg agccgctggg acagcgaggt ctccgctccg cgggggccgg ccccgtgcgc
     6001 acgctgcgcg tactcctcgt ggccctcgaa gtcctcgtac ggctgtaccg gtgacgcctc
     6061 gtcggacgac cagccgggga tctgccgtcc gggcgccgcc gtgacgccgt ggcccccgga
     6121 gtccgggggc tccgggtcgg ggtccgtgcc ccagagtgcg gcggccctcg accaggcagg
     6181 acgctcaccc ggcgccgacg cggcgtgcgc gcgcctcgcg atcagcccgt cgtcccacgc
     6241 tcccgcttcg ccgtccgcgg cggtcccttc acccggctcg gcggcggcat cgccttccgc
     6301 tgcggccgcc tgccgctccc ggttctcgcc gctcgcggtg ggaccgtcgc tgcccgcggc
     6361 ggcgtccggc gcggcctgct tctcttcgga cgagccgtcg atacgaacat ccgttgtgga
     6421 cactgccgtc acctctccgt ctgggactgc gactccgtca acttccgggc tcccggcccc
     6481 gggagaaccg ccgcctccgc cttgcgcagc accgacagcg ccgcgatcag gtcgacctgc
     6541 gggccgggcg ccgtctccag ggcctccagc ggtgccaggc ggcggtcccg ctccccgtac
     6601 agcgctctct ccacgtacgt cgcgagcaac cgcacaccgc actccctcag cttccgcgcg
     6661 ctcacctcgc cgaacgccgc cgccagcgac cggtaggcgc ccgccgcgtg gccgccgccc
     6721 acgagtgcgg tcgccagcag cgccgccgcc tcctcggcgt cccggccgaa accgtggtcg
     6781 accgcgcgcg cctcctcgtc ggcgagctcc tccatgcagc gccgccagcg gcgcacgagc
     6841 aggttcatgc gcccccgccc gtcggacccg cggagacctt ccggcagacc gcggccgcgg
     6901 tctgccggaa ggtctccggt cgcttccgcc gactccccgc cgggcacggc cggttcgcgg
     6961 cgccaggact ccgcgatgcg ctcgtcggcg gcggcgacgg cggaggccag cagcgtggtc
     7021 agcccctcct cgaaggcgtc cagcacctcc tcgccccggc tgtcgacggg gaagccgcgc
     7081 cacagcgcgt cggcgtcgcc cgcgaggagt tcaccgacgg cgatgtgccg ccgtacgcgt
     7141 acacgggcct cctcgaaggc gtcctcgacg tggcccgtca gccgcgtcgc cgcggcgtgc
     7201 tgtgcggcgg aggcgttggc gagcgaggcg acgcgagggc ggagcgacgc gagggccccg
     7261 acggcggtac ggcggccggc gaccgcccgc gcggcggggt ccagggcccg ctgcgcgagc
     7321 caattgcgca ggcccgcgac ggctgttgcg gggagcagcc ccgatccccc ggcggactcc
     7381 ggcagttcgg ggacggtgaa gcgcggcacg tcggccagcc cctcacggat catgagggcg
     7441 ccgtactgcc tcgccacgtc cggggcgatc tggtgcggca ccctgtcgag gacggtgacg
     7501 agcgtgacgt cgtactcctt ggcggtgcgc agcagattcc acggcacggc gtccgcgtag
     7561 cgcgcggcag tcgtgacgag cacccagatg tccgcagcgc acaggagttc cgcggcgagg
     7621 tcgcggttgc gggcgaccag ggagtcgatg tcgggtgcgt cgagcagggc cagaccgggg
     7681 ggcagcgcgg agtcggtctc gatccgcaga ggacgtctgc cgtcgtcctc ggcgtccgtc
     7741 tcctcgacac cgagcagctc gtcgtcggcc gagtccccgc gtgcgccgac tccgaactgg
     7801 ccctgggcgg cgtcttggcg gggcacccgg acccgctcca gccgcggcag gatgcgccgt
     7861 ccggagaacc actcgcggtc gtcgggatgg cacacgagca ccggcgtacg cgtcgtcgga
     7921 cggagcaccc ccgcttcact gaccctgcgc cccacgagcg agttgacgag tgtcgacttg
     7981 cccgctcccg tcgatccccc gaccacggcg agcagcggcg cgtccggaac gcgcagccgc
     8041 ggcatgaggt agtcgtcgag ctgggcgagc agttcgtcgc gcgaacgccg ggcgcgctcg
     8101 gcgcccggaa ggggcagcgg aaagcgtgca gcggcgacgc cttcgcgcag cgcggtaagt
     8161 gcatcgagca gttctggccg tacgttcaag atcgccacat gcgcagaatg cccaaatttg
     8221 ctgccttttt gaagcctatc cacggcactg cgcagcgaaa acaatcggtt tcggatgcga
     8281 atgggccatt cgccccatgt gacccgccac tcgtcaccac cgctgccgac gcacccataa
     8341 cgactgcgca acacccgtac ggcacacggc gaaaaccgct gcacgaatcg caccggcctg
     8401 cgattatcgg gagcgcttca ctgaacctcc acatggtgtc gcggacgtga agcaaacagc
     8461 gccagccacg gggcccccta tccttgacca cgccacggtc acccggaggc acgcccgcac
     8521 tccgcgaccg agaccggccc ccgtagctca gtggatagag caggcgcctt ctaagcgctt
     8581 ggccgcaggt tcgagtcctg ccgggggcgc acacgaacgc cgcgttctac atgcgtagag
     8641 cgcggcgttt cacggttccg gaagtacgag cacgcggcgc gcggacgggg acggggcggc
     8701 ccgcgggcgg gccgagagga aagccccggc cagcaggggg gttgctgacc ggggcggcag
     8761 ggtggagcgg ggtcggggtg cggccccctg gcggcgcccg cggccggcgt caggaagccg
     8821 cgtcgaggat cgccaggagg tcggtggcgg ccgcgcgggg gcccgcgacg ttgccgacgc
     8881 cggtggcgtt cagcacgacc tcgtcgacgc cgatcttccg gtactcgtcc agccgctcgt
     8941 ggatctcctc ggccgtgccg tacaggaaga caccgccgtc gacgagcttc atggcgtccc
     9001 cggagcttcc gtcgccggtg atctcgacac cggccttgcg cagggcgtcc ttgtagtgcg
     9061 gggcctggat gtgctgaccg caggccgcag cggccagatc ggccaccttg cggtcgggcc
     9121 cggagagggc gacgggcacg atggccgtca ccttggccgg gtcgccggag cggcgctccc
     9181 gcgcgccgtc ctccatcgcc ggcatcagcg tctcgtggag gtagtgcgcg gagccgagcc
     9241 aggtgatggc cacatcggcg atctcaccgg ccagggcggc catcttctcc cgcaggacgc
     9301 ccaggcccac ggagacgggc gccggcttga actccaccag gcgcgagacg gacgagtagt
     9361 ggtccccgtg gacctccgtg acctcgccgg acagcaagcc tcgcaccgtg ctgacgtact
     9421 cgcggctcgc cgcgagcggg ctggcgtacg gcttgcccat gaaactgcgc tgggccgcga
     9481 cccctccggg gccgaacccg gccacgacgg aatgccccgt gttgagggcc acggaacgtg
     9541 cttccagtgc ggcctggtac ggagagcgga gcggcatcag ggagacaccg aacccggaag
     9601 ggaccctgat gccgattcca gcgagccaat tgatcagatg atggctgtcc aggagcattc
     9661 cgtggccctg ccacaacctg tgcgcacacg tccagtgcac caggttcgcg aaagggacga
     9721 cctgctccgg acggacagga ccgaagggga ggagaatcga gagccgcacc ccgggaattc
     9781 ctttctacgg gcttttccgc atcgaggtgt gcgcgctgcg ctcccctggc cccgattcgt
     9841 caggactgct tgcggtcgaa tttcatgaac gtggccgctg cgacgacgac ggtcagcaca
     9901 ccgaccactc cggcgagcac ggtgtttccg ctgtatgcgc tcgtgatcgc gatggcgccg
     9961 ccgatagcga cgacgacacc ccaagtgccg cggctcttct tcactgtgaa cctcctgctg
    10021 ctgtccgtcg gtcgagaaca ccactggaaa gcgcgaccgg aaggtgagaa tcgccgacgc
    10081 tttttccagg gctcgttccg gaggactgga gaatgacgtc ggtgtcaccg ataccggacc
    10141 acccgaacat gtatcccaag agggatgtcc ggcctccagc ccctgtataa aatccggtcc
    10201 tccggattct gtcaagaacg agttcctgat actcatgggc tctggtaaag agggatttct
    10261 ctccgagaag gcggccggcg gcgacgagcg actggacgac accgctgctg ccgtggcaga
    10321 cggagagatc gaacgcccgg ccctccggaa gggccgtcgc cttgtcgacc aggctttgca
    10381 gccgcgcacc cttgagccag tccgtacggc ctgccgcgcc gaggatctcc gccgaggtca
    10441 gaagctggcc ggcggcgccg ttgcaccagc ccgcgtacgg ggtctgctcg cccgaggagg
    10501 accgtgagac gagccagtcg gccgactgct ccaccagagc cggatcgtcg agcactcttc
    10561 ccagccgcga acaagcccag cgcagcccca gctcgccgtg ggcgacgtcg aaccacttcg
    10621 ccgttctgtc cgcggagagg tgctcgagag tgaggtcgcg cagcttcccg agctgtttct
    10681 cgtcgcagag aacgctctcc ccgcccactc cgctttcccc gatgcgcgac agcagaacca
    10741 tcaggagacc ggccgggcca ttcgccaggt cgttttcgag ttcgttcgag atcgcccgct
    10801 cctcgattct ctcgaaaacc ttcgccaacc attcacggtc gacgtccgcg ggtctcgtga
    10861 gcagcatcga ggcggcgccc gtgaagacgg attccggtgt ctgcatcagc aggtcgccgt
    10921 acttcgcgag cagacttctc agaccccggt cggctccggc gtgaacggaa cgcagttcgc
    10981 tgtcgtggcg cgacgccctc tccagaaagg tgactatccc gccggagtcg tggaacgaga
    11041 cgaagttgcc cggcgtgatg gtcgagacgt tccgctccgg gcctatgccg cagacccagc
    11101 cggtttcggt tccctccggc ccctcgaacc gcacgccgat ttcgtcgatc cggcgtgcga
    11161 tctccggcca ccaggcgccg gggcgtgcgc tgtcgaggac cggtctcccg aacaggctct
    11221 ccgacgagag tccttccggt ctgtcctcgc ccacgacctc gctgaaacac tcttccagca
    11281 ggaaatggtg gtagaggtcg ctgcgttcgg agttcatggc gatcccgcgg cgcgccatgt
    11341 cgagcggaga ggtcttgtac acccccggaa agccggtcct cagcgtggac agttccttcg
    11401 agtccgcccg cgtcatgaag tacgggacgt tccccgtcga gagcgacgcg cgttcctcct
    11461 ccgccacgta gtcggccgcc tcgggcgaga ggtagtccgg catgcgggcg agcagcccga
    11521 acagccgtgc ggcctcggcg ggctcgcgca ggtagtcggg gtgcgtggag gcgtccagga
    11581 accggccgta gaccatcgtc gaacgcatca ggctgcggac cggcatgccg ggataggcgt
    11641 cgacgacctt cgagatcccg ccgtcacgca cgaaggcgag gccgtcggag tacccggcga
    11701 ggatgtcgct gaagtagtcg ggggccgaca gccgttcgtc tccgaggcgg ggcacgtttc
    11761 cgtggtgctt gtacgtgacg ggttcccagg tgacggagat cctgtccgtg gtcccgtcac
    11821 ggaccgccgc gcgcttgagc ttcgacttct ggtcgccggc gactcccacg cccgccatga
    11881 cgacgtcgat gggcgacgtc gggttcacca cggggacgag catcgtggag accaccgaga
    11941 gcttcatgtg gttcacgagc acgtgcggaa gggagtcgtt gtcgacgccg gcgtcggcac
    12001 ggagcatcgt ctcggtgtcg atgacgctcg gggtctcgcc gcacgccagc aggttctcgt
    12061 cgtgcatgtc cgaggcgccg agggtgccga agaccgcgca gagcgccccg aaccggtaga
    12121 agtagcgcgc cggctggtcc ggggagtcca tcggtgcgga cgcgacgtgc tgctgccacc
    12181 cgtgcgtgtc cgtggagacg gagatcggta tgcagtcgcg cagcgagtgc tcgaggtagg
    12241 ggtctgccgc gtcgtagagg tccttcacga agcggtcgga gaccagggcg cgcggcttga
    12301 agaccagccg tgtcccgccc gtcagccgaa gctggatcac ctgccggttg tcgttgtggg
    12361 ggtcggagcc ggtgaggaag atcttctcga tcagcgcttc ggagtccccc gccgggagca
    12421 gtccggccgc cttcagctcc gcgcggtccg ctgcgcaggc agcgaacagg tcggtgtacg
    12481 cgtcgagcag gttccgccgg atcgtggcga ggcgctgccg gagtaccggg tatctgccgg
    12541 tcagctcgcg gcagttggcg tcgctgccca ggtgggcgcg gaacgcctgg agcgccttgt
    12601 cgccctcggc gtccatgggg agtccgtggt cctcgcggaa ggcgtggaac tccccgatca
    12661 gcgtccggaa ggactggcct tcgacggcgg tgagcattcc gctccacacc tggtccagca
    12721 cctcttcgag gtgttcgggc gcggtgaccg gtgcggcgag gtcgcgcagt gcgtcctcga
    12781 ccgcgcttct gggggccagg tgcgcgtaga aggggaggaa cgccggtatg gagacgtccg
    12841 gttcagccac gttcactcgc ctccgacgac gacatcgagg tccggtgacc tgtccgcgta
    12901 caggtccgtg tagaccgctc cgccgtgcag cagctgcgtg tggctgccct gttcgaccac
    12961 gcggccgttg tcgagcacgt agatgtggtc ggcggatttg atggtcgcca gacggtgggc
    13021 gatgatcacc tgggtggcgc cgatgtgctc gatgatctcg ccgacccggc gctcgttgac
    13081 ggtgtccagg gccgacgtcg cctcgtcgag cacgaggatg ggcgggttct ggagcagcgc
    13141 ccgcacgatg gcgaggcgct ggcgctgacc gccggagaag ttcgctccca tctccgagac
    13201 gagggtcttg aggcccatgg gcagatcttc gaggaagtcg aggatgccga cgccggcgca
    13261 gtactcgcgc accttgtccg cggggatgtc ctggccgagc gtcaggttct ccaggatcgt
    13321 gcggttgtgg agatggatct cctgtgggat gtagccgatc tgccgccgca gcgcgttctt
    13381 gtcgtagtgc cgcgtgtcga cgtcgccgaa cctgacgttg cccctggtcg gctcgtacag
    13441 cccgcagatg atgcggccca gggtgctctt gcccgaaccc gaggcgccca cgagggcaac
    13501 acgggagccg gccgggatgt ccagcgagac gttccggatc accaggtcgc tgtgtttcgt
    13561 gtactggaag ctgacgtcct ccagctggat ggacgtcgag agcagaccgg tgagggtgcc
    13621 gcccgggtcc tccggctccg acttgacgat gtcgctcagc ctggccatgt agcgggacgc
    13681 ctcggtgaac tcggtgtagg tcgagaacac cgacgtcgac agggagaagt aggtcgccga
    13741 gaccgcctgc acggcgatgg ccgcgcccag cgatatgtag ccgtggctga cgaagtagag
    13801 gctggagagc agcaggatca tcggaccgaa catctgggtc gtcgtcgtga cacccgagat
    13861 gcggccctgc tgcatgcgca tccggtcctt catcgcctcc agcgaggagc cgtagacctt
    13921 gccccagctc tccaggaact cgtccgcgta gccgcccatc ttgatcgtgg ggatcgacac
    13981 gatcgcgtcc agctgtgtgg actggctctt gctcagctgg ctgatctccg agtcgacgaa
    14041 ctccatcagc ttcggccgcg tacgggccag gtagaacgcg ttgagcagga acagcacaac
    14101 ggccatcagt ccgaggcgcc actcgacgta gaacaggtag ccggtgacgc acagcagcgt
    14161 ccccacgtcg aggattccct gcgccactct cgacgacagc aggtccctga tcatgttgac
    14221 gctgttcagc cggaacagca gctcaccggg ttgccggacc gtgaagaacc tgtacggcag
    14281 cgacagcatc ttgctgaacg tatgggtcat cagatgcttg cccagcatcg ccacgacgga
    14341 cgagaggacc atgactctga ccacgtgcag ggccaggtag gcggccgcca cgcccaggac
    14401 gacggcgatg accgtgccca ggtcgtcgag ccccttccac ctcgcctgct ggtcgaccgc
    14461 ccattccgtc agcatgggaa tgcccagcac cgcgccgtag ccgctgaagg agagcaggcc
    14521 gacgagggcg atccgcttgc gcgaaccctc cgcgaagagc gggatgtcgc gccactccgt
    14581 catcggcttc tgacgcgtct tctcgaagtc cgggccgacg tccgcggaga cgacgatgcc
    14641 gctgaagccc tcctccagct cctcgcggct cagccgccgg cgcccgacgg ccgggtccat
    14701 gacggtcgcc ttctgaccgt cgaacttctc gaggacgacg aagtggtact cctcccagta
    14761 gaggatcacc ggcgaggtga acttctccag cgcggagacg ctcttggcgc ggaagagctt
    14821 cgcgtccatc ccgcgcgtgc gcaggtagcg ggcgagctga ccggcgctca gaccgtcgcg
    14881 gccggcgtcc atcacggcgc gagcgctgga gaggtcctcc gcacgcccgt agtagcgcag
    14941 cagtgcgacg gagcagcaca gcccgcactc tgtctgcgtc acctgcgtga gcgtgggcac
    15001 gcggcgggcg tgcttgcggc tgcggagtgt gaggctcatg tcatcggctc tcaaaggtaa
    15061 gggtgaccgg tgagatgtga acgctcggat cgagacggtt gacgaggtgc aggacgatgc
    15121 cggcggtgcc gaccatgagg ctgttcgtgt gcgcgtaccg gctctggttg tcgttggtct
    15181 tccgtatgag gacgtccggc tggagccacc gctgctcgat cttggcgacc tcctcgcgca
    15241 ggccctcgtc gtccgccgcg agcttggcga gcacgtcgtg gttgcccagg tcgccgtggc
    15301 accacgtcag gttccgcccg aagccgtggc gtacgaggtt gccgatcgcg acgtcgcgca
    15361 tgcagttcac gacgtcgtcc ttcgcgacct gaccgtacga ggacagtgcg agggcgatgc
    15421 cggtcgcgcc gtggcaccag ccggtcgaga acgaccaggg cgtggccgcg ttggagaacc
    15481 agttgccctg ctccctgtcg tagaactcct gcagccggcc gacgaggtcc ttcagggtgg
    15541 cccgcacgac gtcctgctgc ccggccggca cgcgcggcag agcgccgctc agcgcgtgca
    15601 ggagcccgct gacgccgtgc gcgaagccgg actgggcgaa gacggcgccg tgcccgtccc
    15661 ggacggcgtc ggtcagcatc cccgtcaggg ccgccaggga cccgtcggcg tgcgggccgc
    15721 cgatcgcggt gacgcagccc atgacaccgg cgacgccgtt gaccacgtcg atggggagcg
    15781 cccgcggatc gatgtcgcgc atctggtcga ggaccagcgg cagggcgccc tgggcggctt
    15841 cgacccactc gtcgttctcc agcagccggc ccgtggtggc cagtgcgaat aggatgccgg
    15901 ccatgccggt gtagccgccg aagccggcct gctggatgct gcgcctctcg taccggtgcc
    15961 cggcgaggat gtccgccatc gtggagaaga tctgcccggc cagatcccgg tactcgccgc
    16021 ggtccaggaa ccggccggcg gcggccaggg ccagcgcggg gccgaccctg ccggtgtaca
    16081 ggtcgtatcc gagcactccc ggcggccagg gcctgttggc cgcggccgag gcgaggggtc
    16141 cgatccaggt gcgcggcagg tgcgcgaact tgtcgggcag cgatgtctcg acgaggttgc
    16201 cggcgaggcg ctcgacgagt tcgacgagct cgccgtggga gtcacccgcc gtcccgcggt
    16261 ccgacggcgc gtggaaggct ccgccgtccg aagtgccgga ggcggcgagg tggttgtcgg
    16321 ggaagcggga ggagaaggcc gagtagacga gccggagctg ctcgcgcagg tcggtctccg
    16381 tcatgtgcgc cgtcttcgcg agggcgcggt cgaccgggct ctcgtcgaag aaggctccga
    16441 cctcgcggcc gtccccgtcc tccagggcga cgcctgtcgc ggagacggtg aagtagggga
    16501 tgtcgcgctc ggccagctga cggatctcgg agcggacgat ctgccgggac gaggtcttgc
    16561 tggcgatcgc gatgcgcttg agcagcgcga tgtagggcga gacgtcgtcg agggcgccgg
    16621 cgctggacgt catccgcagc gtctgcgcgt acagcgccgt cgggttgtgg acgtagcgca
    16681 cacgcatgcc cgacgccgct ttccgcagca gctccgccca gctgtcctgg gaggccatca
    16741 tcgtgcggaa gacgcgggag aacccctcgg ccatccggtc gcccaggacg cggacctcgt
    16801 cctcgcccag ggagttgacg accgtgcggc ggccctgcgc ctcctgggcg cggatcacca
    16861 ggctgatgcg gtccgtgtac gggttctcga agaagatcga cttgaacggc gaggagcccc
    16921 gcccctggtc gccgaggaac ccgaggtcga cgtggccggc gtcctcgccc tttccgacca
    16981 tcacgagcgg caggatgccg atgccgtaga tggactgccc gatcgtctcg taggcgttcc
    17041 ccacggcctc cggcgtgggg ccttcgtgga cgcgcgccgg gtgcaggatc gtctcgaggt
    17101 cgatgggcac ggggccacgg cgggtgggca ggatgttctc gaagtgcatg tcgcgcgcgt
    17161 tgaggaggta gagcaccgcg gcgagttcgc cgctggcgcg catgaactcc ccggacatgt
    17221 ccgagacgtc ctcggtctcg atgaactcga cgtatccgta atggttccgc tcgaggacct
    17281 gggccgcggc cagtgaggtc ccgatctcct tgttgagttc cgtggcgatg tgctcgtacg
    17341 cggcttcgca ggagacgtcg cggggcttgt agacgagctt cttgccggac tcgaactcga
    17401 gcacggagac gctgcgtccg tgattgtggg cgtctccctc ggagaagccg caggagacga
    17461 tccggtccgg gacctcgatg ccgaaggtcc cggcgatcgc ctcgcggtcc gcgacgagcc
    17521 ggcggcagag ttcggcgacg ctctccgcgc cgttggcgag caggatccgg gtgatgtcgc
    17581 gcagcacggg gaaggacagt ccgctcacct cctcgaagga cgtgagcctc gcctggtcga
    17641 cgaagtaccg gtagcgctcc tcggaggtct ccccgacgag ccgtccctcc tcgcgcgcgt
    17701 ggttgatcgc ggcgaccagc ggacggctgt agacctcgcg caccctgctc tcggtacgtt
    17761 cgagcagctg caccagcatg gcgtccgggt cgctgaagag cttcccgaac ggggcgacgg
    17821 ggtcggttcc ggcgacgccg gcggcgacac ccctgatgat gctctggaac gggtactgct
    17881 ccggccggcc gagccactcc cgtaccgtcg cgcgcgtccc ctcgcccggc gaggggcgct
    17941 cgtccgcgct ctcaccgccg gcccggagca caccggtgaa ctggtcgtcg aactgcgaca
    18001 gcgggacgat tgtttcttcg acttcggcgc tgtcgaactc cgggtagtac ttggctggag
    18061 aaatcacggt gttgctgctc ccgttttcgc gagatgtcgt cagacggccg aagtcgaggc
    18121 cgcggaatgg aggcccgaaa ggggcctcca ttccgcttcg tactgctaca tgaccaccga
    18181 gagaggtgaa gtcacattca gcactggctg gtgcacttcg tggtggggca gatggccgcg
    18241 gtggccagcg tgaccgtggc gcagacccac gccgtgccgc cgtaggcgtc ggcgtcgctc
    18301 agctcgacga gctcagcctc gtcgtaacca cccagaatgt cgtcgctcat gatctacctc
    18361 ttcccttttc tgtttttctg gtcagttgca gttcggctgg cactcgacgg tcagggtgca
    18421 ccagccgccg gtgttgccca gcacgtcgga gagggagaag gtgttggtgg tgcaagcacc
    18481 gtaggcaaca ccgtcgaagt cctgctccgc gatttcttca accagcgaaa cgtcgccctt
    18541 gtacacgatg gaactccatt ctgcgagtac agacatgaat tgctcttgcg caccggtggc
    18601 gctccgaccg cgtacttctg aatttctttg cgatccgcgc cccccagcgg tgcgggctag
    18661 acagtatttg ctccatggtt tcgccacaac aattttccac acgtgatcca catcacatga
    18721 catctgtcag ttgactggcg tggacaaggg gcggaacaaa gaattccgga tgttacgccc
    18781 cgctcccgga agctccgccc cgcattcgag acgtcgcacg aaacggcagc tcaagaacca
    18841 tgaaaaggct ttcctggcgc cgtcggaccg gggccgaaat cacggatcaa gtgattccgg
    18901 atgttatgga agaggacctc ggccgcgaac tccgcacgac ccgcgggacc ccctccccgg
    18961 acacgatcgg aatcccccgc tccgaatgtg ctcggaattc ccggactttc acccgccccc
    19021 tgtggggatt cattgcggtc cggggcttac tccacctgga aggcgttatg tccgaaatca
    19081 cgggtggccg ccggtcgagc ctccggaaag acaggagaag cccgcccggc ggccgcgccg
    19141 gaatgtcgcg attctccgcc gaaaagggcg ccctgacggc tggtcaggcg tcccggcggc
    19201 gcatcgcgta gtaccccgcg gcaacggcca gcacggccca ggccgccagt acggccatgc
    19261 ccgtccaggc cgtcagcacc ccgtcgccgt gcggctcctt gctgcgcagg atgaggccgc
    19321 cggccaggtc gggcaggaac tgcgcgacct tctgaactcc gggaatgctg ttgaggatcg
    19381 tcgagatcat gaagaagagc ggcacgagga tgcccatggt cagcgccgaa ctgcgcagca
    19441 cgctcgcgag gcccatggag aaggcgcaga tcagcgtcat gtagagcact cccccgatga
    19501 gggcgcgcag cacgccgtcg tcggagaggg agacgctcgc gggagagccc agcatcatct
    19561 gcgtggcgaa gaagctgagg gtcaccacga cggccgagac gaccagcgcc gtcgccgtgc
    19621 cggtgagcag cttcgccgcg tagaggacgc cccggcgcgg tacggccgcc agtgagctgc
    19681 ggatggagcc cgtcgagtac tcgctgctca cggtcagcac gccgaagacg accagtgcga
    19741 tcatcccgag tttcatcccg ctgaagccgg aggcgaccgg gtcgaagcgg gcctgcgcct
    19801 gcgcgtccag gtctgcgtag gtaccgcgca tgacgtaacc gaagagaagg gccacggcca
    19861 cgctggcggc ggagaagaga gcgaggctcc agaccgtgga ccgcagtgtg cggatcttcg
    19921 tccattcgaa cgcgactgcc gcgccggtgt ccgacatcgt caccgcacct ccaggtccgc
    19981 gcggaagtcc accgcgtccg cggtgagctg catgaacgcc tcttcgagcg aggccgtacg
    20041 ggggctgatc tcgtagaccg tcacctggtg cttcgaggcc agcttgccca ccgtctccaa
    20101 ggtggtgccg agtgcttcga gcacgccttc gggcccgttg tccgtccgga tgccctcgcc
    20161 ggccaggaca tcgcgcatgc gctcgggttc gggcgtccgg atgtggatgt acgagcgcga
    20221 gttgcgggcg atgaagtcct cgaccgtggt gtccgccagg agacgcccct gcccgatgac
    20281 gatcaggtgc tcggcggtca gggccatctc gctcatcagg tggctggaga cgaagaccgt
    20341 acggccctcg ccggccagct tcttcatcaa ctcccggatc cacaggatgc cttcgggatc
    20401 gagaccgttg acgggctcgt cgaacagcag cacctccgga tcgccgagca gcgcggccgc
    20461 gacgccgagc cgctgcgcca tgcccaggga gaacccgccg gcgcgcttct tcgcggtggc
    20521 ggacagcccg accgtctcca gcacctcgcc cacccgcgct tcggggatgc ggttgctgcg
    20581 ggcgagaccg agcaggtgcc cgtacgcggt acgtccgccg tgcagggcct tggcctccag
    20641 cagcgcgccc accttccgca ggggctgagc gatctgctcg tagcgcctgc cgtcgatgag
    20701 cacctggccg gacgtcggcc ggtccaggcc gatcatcgcc cgcatcgtcg tggacttgcc
    20761 tgcgccgttg ggcccgagga agcccgtgac gcggccgggt ctcacctgga aggagagccc
    20821 gtcgacggcg agcgtctccc cgtagcgttt ggtcagtttc tgaacctcga tcattcgacc
    20881 ccgttccccc ttgcgtagac cggcaactga gcgcacttgg cccgggagcg acctccccga
    20941 ggccgacgcc gctgcggtgg gatgagtgaa ggcggcggag aggatctctg aatccgccgc
    21001 gtgttggcgc cggacatctt cgcacggcct tcacgttcgc gggacggttt cacgggacgt
    21061 gccgatcttg acgattccag gcgatttgta cgactgatcg cgggacgacc ggttccgtgg
    21121 gagagccggt ccggccctgc ccgtccgcac agagccctgc cctctccccc gggggccggg
    21181 caccgtccgc gcctggcgcc cgtacccgta cggcggagca gatgacgcgg accgcccggc
    21241 gccgtgccca ggatggagcc atgtcgtctc acgaacctgt ccgtccgccc tggccggcac
    21301 cgccgtgcgt cgggcgccgg acaccgcgtg gtggaccgcg aggcgtcccg cgatcagcag
    21361 acggccgggc cggcggtgcg gacgccgccg gatcgaggag aaggatgggg atgcgcgcat
    21421 gagtgacagc ccgaaggccg cgcttgcggc gagtgtcgcc gccggatacc tcctcggacg
    21481 gagccgcaag gcgaaactcg ccatcgccgt cgccaccttc atggtcagcg gacggctcca
    21541 gtccaaaccg caggagctgc tggcctcggg cctgggccgg ctcggcgact ccccccagtt
    21601 cgcccagctc gccgaccagg tgcgcgacga gttgctgacg gtgggacgcg aggcgctgaa
    21661 gacagccgtc gaccgccgcc tcggcacgtt cgcggactcg ctggccgagc gcacgtcgtc
    21721 gctcaacggc ctcggcggcg tgctcggcgg cgttcagggc ggtgacgaag acaacggggg
    21781 cgacgacggg gacgacgggg aacgggacga ggctgcggac gagcgtgagg aacccggcgg
    21841 cgagccggag gaggaagagg agtcgagcgg gcgcggcggg gagggccgcc ggaggccccc
    21901 gcgcgagcgc cgggacgaac aggccgcggc accgcggaag cgcgcgaaga agaccgccgg
    21961 caagcccgcc gcgaagaagg cccccgccaa gaaggcgccg ccgaagaagg ccgccaagaa
    22021 gacaggcgga cggaagaccg ccagcaattc gcccgccgag cagcgccgcc ggaggtagga
    22081 gccatgccgc agaaggactc gggcaaggac gccgcgaacg acggcggttc gggcctggac
    22141 cgggtacgcg aggaactctc caactacctg accgcgaaga cgagcaatct cgtcagctcg
    22201 gcgggcggca aggtctcggg gctggcgcag aaggtcgccg agggcggcgc tccgggcggc
    22261 ggcgacctgc cgaagatggg ggcgaagctg ctgaagggcg agtcgccggc gaaggccgtc
    22321 ggcggtcaaa tggtcaagaa ggtcaaggac aagaccgtcg gcaaggtcca ggaactcttc
    22381 ggcggcgggg gcgaggccgg cgacaagaag acgaccaaca tcgtcgaggt gctcgacatc
    22441 ggtctcccgc tgcgcagggt ctacgaccac tggaccgagt tcgaggagtt cagcagcttc
    22501 atgaagggcg tggtcgaggc gtcacgcggc gacgacgaga ccacgtccga atggacgggc
    22561 aaggtcggcc cctcgaagcg cagttggaag gccgaggtcc tcgagcaggt gcccgacaac
    22621 cggatcgtgt ggaagtcctc gggggaggcg acgacccacg gcagcatctc cttccacgag
    22681 ttggcgccga acctgacgcg gatcgtggtg gtcgtcgagt acacgcccgg cggcttcctg
    22741 gagaagacgg ccaacctctg gcgcgcgcag gggcgccggc tccgcctcga cctcaagcat
    22801 ttcctccgct acgtctcgct cggcgtccag gaggtcccgg agggctggcg gggtgagatc
    22861 cgggagggcg aggtcgtgcg cagccacgag gacgtgctcg ccgaggacga ggaggaccga
    22921 ggcgacggcg ggggcgagga gcgggacgag ggcgatgcgg aggaagaggg gaacggcgag
    22981 gacttcgagg acgaagacga tgaagtagac gaagacgaag aggaccggaa cggcgaggac
    23041 ttcgaagacg aggaagacga gtacgaggac gaggacgagc gcgagtacga gacccggtga
    23101 cgcgcgggac gccgggcctc ttcctgcggc gggcccggcc gagcaccggg aacgccctgg
    23161 gtcctctccg ctctgacgag gaagcggaga ggaccggctg ccgggtcggg tgaccgtctc
    23221 cacgcgtgcc gcggcgcggt ggcgggcgtg cgcggcggcg gagcgtggat caggaggtga
    23281 cggtcacgtc cgcgccgggg tctgtggtgt cggtgatctc gtaggtcgcg ctgaaggcgg
    23341 agctggtggc gctcgtcggg cagccgaatc cgccttcgac cgtcacgggg acggcggctt
    23401 cgtcgaaggt cagagtcgac ggtgaaccgt tggcccatgt gccggtcgcc gtcgccgcct
    23461 cggtgggagc ggcggtcacg gtgcactcgg cgagcccgct ggtcttgagc acgaaccccg
    23521 cggtcggcat ggtgagtccg gcggtcgcgg gcgcgccgtt ctgcatggag accgtccagt
    23581 cgccggtggt ctccacggtg gcgtcgacgc ccggcaggct cgccgtgcag gagtcgtagg
    23641 tgggcgggtt gatgcccgac tcgacaggtc ccgcgtcgtt gtggttgccg ggcgcggccg
    23701 ggatccggcc ggtggcctcc gagacggtgc agctcacggt caccgatccg gcggtgaacg
    23761 tcgcttcgcc ggtgagcttc gcggcgtact cgtctccggc cggtgtgacg gtggtggatt
    23821 cggcggcggc cgtgccggcg gcgccgctga gcggggtggc gctcgcggcg ccggccgcca
    23881 ggagtgcggc ggcggcgacg atgccggtca cgacgacccg taacgaccgg gcgggctggt
    23941 ggcgcgtgct catcatgcgg ctccttgtag ttcggctcgc ggaaacagaa ggggcgatgg
    24001 cactcgttcg ctcagtctta ctcggggctc cggctcgttt tgctgttccc cgacggggtg
    24061 ccgggggatt cggggggcgg tggctgctgc gggacggaga aggccgaggc cagcgaggag
    24121 agcgtgtcct ccttggaggc gtccgcggcc gtgccggccg aagcgccgcg cgccgtgccg
    24181 gcgagggtgc ccccggcgcg gccgccgtcc gcggccgctc ctgacggcgt gccggcgtgg
    24241 gccgccgtgc cgtcggccgg ctccgcctcc gtctgcccgt ccggcggcgg cccggccgga
    24301 accggccgcc acgcgaagat cagggcaccg ccgaccacgc ccagcagcgt gccgatcacg
    24361 aaaccgccca ggttggacag tacgagcgcg gccgtcgcga gcagcacggt cagcacgccc
    24421 gcgagtcccc tgtactgggg gccgaaccag gcgctgaacc cgaggaccac catgaccagc
    24481 cccagtacga cggtcggcag cccggccgtc ccctggtgca gcatcacctt cagcggagcc
    24541 agtgggatga ccgcgatctc cgtaccggcg aggacggtca gcagaccgcc ccagaaaggc
    24601 cggccgcggc gccacccgcg ccaccggcgc cagatcagaa gcattccttc gtgcccttgt
    24661 tcaccttcat gctcaggccc gacagcttga acttgcccgc gttcgtggcc caagcggtct
    24721 gcttgaggct ggagatgtgg acgtcgtccg cctgctggcc gaagaggtcc tggaggccct
    24781 ggccgccctt ggggcccttg tcgagggtcg aggcgtcccg gccgatctcg atcttgttga
    24841 agccggcgtc gccggagagc tgcgtcgcgt cgacgaagag gtcggtggcc tccaccggct
    24901 tgctgccggt gcccgcggtc aggttcagcg aaatgctgcc gatcacggga agtttggtga
    24961 cgacggactg gcagaggtcc cgcatctcgg cggtcttgat cccggtgacc gccacgggga
    25021 tcaactcgcc cctggcgttc ttgtcgatgc tgccgtactg gacgaagccg tcgccgtcca
    25081 ggctcttcgc ggacaccttg aactgctgtc ccgacacggc gaacgacgcg gcgagcgctc
    25141 cgttggccag tgcgatggcg agggccgccg tcgccgcgaa gcccggcacg cacaggacgg
    25201 cgaacttccg ccaactcgtg cgtcctgtca gcggtctgcc gtgcgcatcc ttcatggtgt
    25261 gtccccttga gtgcagttga cgagcgtgac cgtggtgtgg gggatgtgga gcacgtgcga
    25321 ggtatcaggg gggagcgcac agaaggcgac cctgccgtgc ggaagagtta ctggcgagtc
    25381 aggttatgga caccggcgat tcccggcaag gtttcgcgca gtcgagtttc cgccgaagct
    25441 ctggccatgg atgcgaacgc tcggcgcccg gcggccagtt gcggccgggc gtccgcccct
    25501 cccccgcgcc caccaggtac gtaccgagct ggcgttacct gaagtagcag gcgtgcggcg
    25561 cgagttcggg cccgccgggg gccacggggc gggggcgcgg cgagcgctca gacggttgga
    25621 tcagtggccg aaagcagttc gtcggacacg ggccgggagt gcgccgaggg gccggcggaa
    25681 gcgggaagcg gcgaggagcg gagccgcgga cggggcaagc gattgcggaa cgccctgtgc
    25741 ggcgggtggc ccggacgccg ggcgccgcag ggaagttgat caccgtcggg ccggtgctcc
    25801 ctcgtcgcct tcttgccgtc gccttcgggg gcgtcgtacg atgaatgcgc tttcaatcca
    25861 tcggccggca cggccgcggc aaggcaggag agcatcggtc gcgtgagtgc tcccactgtg
    25921 tacgacgtcg ccggacgggc gggcgtctcg atcgcgacgg tctcgcgagt ctaccgcgcc
    25981 ccggactccg tccgcgtggg tacgcgggag cgcgtactgg aggcggcacg cgaactcggc
    26041 tacgtgccga gcggcaacgc ccggggcctc gccagccgca acacgcgcgt cctcggcctg
    26101 tgcttccccg actacgcgga cccggacgcg gaggaccccg acggggacta cggcgacgcc
    26161 gagttgatgc tctactccga cgagataatc cgcggcatgg agcgcgccgc ccgccgccac
    26221 ggctacgcgc tgctcatcgc cgcgtctctc gcggagggcc ccaagagcct cgtggccgac
    26281 gtggccggcc gggtcgacgg cttcgccgtg ctggcccgca cggtccccac cgaggaactc
    26341 gaggtgatct cgcggcggct gcccgtggtg atgctggccg gtccgcgcga ggacgcgccg
    26401 ctcgaccacc tcgaccacgt ggaagtggcg aacttcgacg gcgaactggc tctgaccagg
    26461 cacctcatcg ccgatcacgg catcacgcgg ctggccttcg tcgggagcac ggaggactcc
    26521 cccgacggcg aggcccgctt ccgcggcttc caggccgctc acctggaggc cgggcttccg
    26581 gtgcccgagc gcccggacgt acggacgagg ctgacgcagg ccgaggggcg ccaggccgtc
    26641 gcggagctgc tcgacagcag gtcggagctc ccgggcggag tcgtgttcgc caacgaccag
    26701 atggcggtcg gggcgctctc cgaactgaac cgccgcggag tgcgggtgcc cgaggacctc
    26761 gccgtggcgg ggttcgacgg catcccgctc ggacgtctgg tcacccccgc gctgacgacc
    26821 gtccgccagc cgatgcgccg gctcggcgag gaggcggtgg acctgctggt cgcacggctg
    26881 gaggaccgcg accgcgagcc cgagtcgcgg gtgctgccgg tctccgtgat ccggcggtcc
    26941 agctgcggtt gcgcgaacgg ccacgacgcg gtccccgaca cggcttccgt tacatagtcg
    27001 taataccccc gggccttgca cgcccgggcg gtcgcttcca gagtatgtat gcgcttacag
    27061 actctcttac ggccacgcgg ccgcccgagt cccccggcct cggcctacga acatccggcg
    27121 ccccataacg ctccgctaac gaggaggagc ccctccatgc agcccatacc ccgcatcgcc
    27181 gccgccacag cggccacgac cgctctcgcg ctgctgctca ccggctgcgg cagcgggggg
    27241 agcgaacagg cctccgccaa ggacaagcag accctcaccg tctggggcat gggagaggag
    27301 ggcaagcacc tcgcgaagct cggcaaggag ttcaacaaga agcactcgaa catcacggtg
    27361 aaggtcactc cggtcggctg ggacgtcgtc caccagaagc tgacctccgc cgtggccgcc
    27421 ggagagctcc ccgacatggc ccagatgggc agcacgatga tgggcgagtt catcgagctg
    27481 gacgccctcg agcccgtcga cgagaagacc ttcgacaagg gcgacttctt ccccgccgcc
    27541 tggaacagcg gcgtgaagga cggcaaggcg tacggcgtcc cctggtacgt cgacacccgc
    27601 gcgctctact accgcacgga cctggccgag aaggccggag tggacgagcc cccggccacc
    27661 tgggacgacc agcgcgagct cgcgaaggcc tacaaggaca aggcgaaggc ggagtggggc
    27721 acctaccacc agcccgccaa cgtcggcacc tggcagacct ggctgccctt cctctactcg
    27781 gccggcggca agctcctcga caagtcgggc aagcccgccc tggactcgcc ggagtccgtg
    27841 aaggcgctgg aggagtacgc gcactacttc gacaagggcc tgtccaggaa gagctcgccg
    27901 ccggactacg acgtggtcaa ggacttcggc tccggcgacg cccccatgtt catctccggc
    27961 ccctggatcg tgaacaacat caaggaccag cagccgcagc tcaaggggaa gtacgccacc
    28021 gccccgctcc cggcggacga gtccagcacc tcatgggtgg gcggcgc
//
