LOCUS       NZ_LT575476            21380 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Paenibacillus tuaregi strain Marseille-P2472T, whole genome shotgun
            sequence.
ACCESSION   NZ_LT575476
VERSION     NZ_LT575476.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus tuaregi
  ORGANISM  Paenibacillus tuaregi
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Paenibacillaceae; Paenibacillus.
REFERENCE   1
  AUTHORS   Urmite Genomes Urmite,Genomes.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2016) URMITE, 27 Bd J Moulin, 13385 Marseille
            Cedex 05, France, 13385, France
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900086655.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:49:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,150
            CDSs (total)                      :: 5,039
            Genes (coding)                    :: 4,993
            CDSs (with protein)               :: 4,993
            Genes (RNA)                       :: 111
            rRNAs                             :: 7, 8, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 91
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 46
            CDSs (without protein)            :: 46
            Pseudo Genes (ambiguous residues) :: 0 of 46
            Pseudo Genes (frameshifted)       :: 12 of 46
            Pseudo Genes (incomplete)         :: 33 of 46
            Pseudo Genes (internal stop)      :: 6 of 46
            Pseudo Genes (multiple problems)  :: 5 of 46
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:50:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 204604
            Orig. end                         :: 225984
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LT575476.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21380
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21380
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21380
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11380](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11380)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    797..813
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.02"
                     /tool="antismash"
     misc_feature    complement(985..1005)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.46"
                     /tool="antismash"
     gene            complement(2051..2959)
                     /locus_tag="BN6628_RS01355"
     CDS             complement(2051..2959)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019419737.1"
                     /locus_tag="BN6628_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EamA family transporter"
                     /protein_id="WP_068613209.1"
                     /transl_table=11
                     /translation="MWFVFALLTALAWGGADLFYKKGSDSHDRYSHIKIVIVVGLVMGI
                     HATAYMLIQGLSFNPIDMLRYLPVSALYILSMTLGYIGLRYMELSIASPVQNSSGAVTA
                     ILLFIFFTHDLSLIEILGIAIITCGVVGIAVLEKRAEHEALQNHSTQIDRKYQIGFMAI
                     TFPILYCLIDGLGTFADGIYLDELNLISQDAALLAYEFTFFICAVLAYTYLKFVKKQPF
                     NLFRERVKGYAAILETTGQFFYVFAMSSNAIIAAPLIASYSIFSVILSRIFLKERLNAK
                     QYAVVMIVIVGIALLGLADEL"
     misc_feature    complement(2973..2989)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.32"
                     /tool="antismash"
     misc_feature    2974..2989
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(3150..3165)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            3238..5630
                     /locus_tag="BN6628_RS01365"
                     /pseudo=""
     CDS             3238..5630
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431396.1"
                     /locus_tag="BN6628_RS01365"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHRMNVEFIDHVDRVISWLSRRRLSTLHSFIHRSWKRIMCLP"
     misc_feature    3262..3276
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            5806..6153
                     /locus_tag="BN6628_RS01370"
     CDS             5806..6153
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6628_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_068613214.1"
                     /transl_table=11
                     /translation="MDWLNKGIAERWRAEGIRYASDINEYVRVGNETGWPEDLKPPEED
                     QRRSIAGDILQMIREANRCGETKKLREEIPPASWPITSEFPDKLQPVKPLAFLQDGSLL
                     VHAGSGSAGQD"
     gene            complement(7030..8706)
                     /locus_tag="BN6628_RS01375"
     CDS             complement(7030..8706)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="BN6628_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_068613217.1"
                     /transl_table=11
                     /translation="MLLNYMNFIFKYLFGSKLMLVSILLLSILTSIINLFTPYVTSLLF
                     DSGILGSNIYLIVSISFSLLFLSIIKFFIKYFGQILHAQLSVKFTTSIKKDMYSHLLRL
                     PMRYFDNNHKGYLLSRIDEVDALSVLFSSAIFDFFAALITAVGAFYYIFNKSWILLMIS
                     LAFLPVFYFLTSASLKGIYTKSRELYEVNATTKGKLQESIEGIQELKQLNNEERTFKDL
                     TNQVNKLARKITEQSKFAAMGTEGVSLLLNISQIIITLTIGILIVRRQLSIGDYVALTQ
                     YVMLLYAPVQLIAGFSLTIQPGLVALDRVSSILKMDTEEKEIGIKIEELTSIQFKEVSF
                     KYEGATDYVLKGISFTLDKNEILAIQGANGSGKSTIIKILLGLYREYDGIIEINGINFK
                     DINIESLRKCIGIVSQNVILFSGTLLENIKMANPNISVEHLNNLLDIFQDKMFKDIDPY
                     SMVLNEKANNLSGGQKQKIALLRAFAKDPDILIFDEATSNLDTESKAFLEEAIKKIFNN
                     KMCIIISHEENNNSIADRIVEIVDGVLIERKYSTSLSTGSS"
     misc_feature    8673..8686
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.76"
                     /tool="antismash"
     misc_feature    complement(8676..8690)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.47"
                     /tool="antismash"
     gene            complement(8770..9978)
                     /locus_tag="BN6628_RS01380"
     CDS             complement(8770..9978)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024747.5"
                     /locus_tag="BN6628_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4Fe-4S cluster-binding domain-containing protein"
                     /protein_id="WP_068613219.1"
                     /transl_table=11
                     /translation="MKFLILKSNCAIVVGNNGSFIYDIANKDYYSLDVHHTEILNKVKK
                     GMCIEEIKNEFDVNVVNDFFNKLIESNLAELADYYYVEEVTRIGHARPVSNMQLNTCYI
                     ELPSSCEVNCKSCRSLKLFSCLTCSCPTVTSPELDMEFYRSLLSDVLKMSVQTLIFHGG
                     DPLTFGDSILELLQYTRENAHENVRIILKTNGRLLDTKMIHHFIKFKINPLFVLRCTNE
                     NNHQISMLETSPETFQVFFENKLEYFCNVVMDSPTQLESVIQKLKNYNFSNISTSLLID
                     EKSNLQTYARVQFSDKLSYNFMLNKNLHPCLMGVIAITADRKVIPCPSMIKHPLLDLGK
                     SHILDLFQYPEILNEFWRFSLEKIERCKACKIRFSCVDCRAVEELLSNDLYKKEICYLG
                     HSN"
     gene            complement(10001..11380)
                     /locus_tag="BN6628_RS01385"
     CDS             complement(10001..11380)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="BN6628_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_082926740.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     3.4e-09, bitscore: 35.0, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.3e-46, bitscore:
                     157.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-10, bitscore: 40.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.3e-14, bitscore: 50.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRGFFFTTNKGNSYYYDDDTSNVKFQGNYEKSNFIFGNSQLQE
                     ASINRKELEDYLDDNSGSQLILLTTQACNIRCTYCVYSGNYENQRSHKREFMSVETAKK
                     AVDKYLKNFKQRKFKNPFDNPLIAFYGGEPFLNYELIKEVVSFTKEKYHNKVQFSTTTN
                     AILLNDEKIHFLAKHSFALSISLNGDRDEHDRMRVFKDGSGTYDIVMRNLSRIRELYPD
                     YFKEYCQLLITIDTGSNLMKLRDFLKENQSILPKIARISQVGTSFTNWYDQYSAEEKEE
                     FINSFNKLKSVYIDQVRSPDGIEADAFLKILFSVPMFSILNRSRNIPFQSRRPAFLPYT
                     GACVPGEKIAVDTSGNLHVCERVNQTRSIGDVDHWLKISSIMRMIEDYQRNITKDCPNC
                     PVHSLCDICYAGVLDGDGEFDKSYMEPNCQKIRTHIQKQFAEIWSLMEEGILAEELIPN
                     F"
     aSDomain        complement(11102..11371)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BN6628_RS01385_Other_Sactipeptide_rSA
                     M_RRE.1"
                     /evalue="1.90E-11"
                     /identifier="RREFam021.1"
                     /label="BN6628_RS01385"
                     /locus_tag="BN6628_RS01385"
                     /protein_end="93"
                     /protein_start="3"
                     /score="35.0"
                     /tool="antismash"
                     /translation="RGFFFTTNKGNSYYYDDDTSNVKFQGNYEKSNFIFGNSQLQEASI
                     NRKELEDYLDDNSGSQLILLTTQACNIRCTYCVYSGNYENQRSHK"
     gene            complement(11515..11673)
                     /locus_tag="BN6628_RS25985"
     CDS             complement(11515..11673)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6628_RS25985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157692447.1"
                     /transl_table=11
                     /translation="MEQMNNVTPQSGWTCSISCAGPCFVACAAGVETGPAALAIVTGSF
                     LYNSYAN"
     gene            12444..13769
                     /locus_tag="BN6628_RS01390"
     CDS             12444..13769
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007131291.1"
                     /locus_tag="BN6628_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_068613221.1"
                     /transl_table=11
                     /translation="MDWLNKGIAERWRAEGIRYASDINEYVRVGNETGWPENLKPPEED
                     QRRSIAGDILQMIREANRCGETKKLREEIPPASWPITSEFPDKLQPVKPLAFLQDGSLL
                     VHAGSGSPGGTLYRAHAGDLTEITGANYAGSSRDGAYVALVNEQGIRVVKGMTGDTEGE
                     QVAVFRWKDVQGRLKAALPDLESLADGEHPERHMDEVIPVDGGRRVMLVCGYGIYLLGG
                     GEGEVEVELLHPELADLREYESEDTIVDMAHGDISPDGRWLAYGSQSSEHQLKDLQSGA
                     VYAYEPASSYPHFARFSEDSREVWFNACHFYNGATFKVPLAEAAQKREWGSPEEWLLTN
                     EEMRVYAGVSLQEGYILGDAYGYLRFIDRKGQEIWRYFVGSTISGMTLTVDEKVLAVGT
                     YGGMLHLLDLKCGQKSEYSIGTAAILETDRWMLWQNQEPLSW"
     misc_feature    13774..13788
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(14117..14131)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.98"
                     /tool="antismash"
     gene            14122..15081
                     /locus_tag="BN6628_RS01395"
     CDS             14122..15081
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015734984.1"
                     /locus_tag="BN6628_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_068613223.1"
                     /transl_table=11
                     /translation="MSAIHMLAGIPGSGKSHYAKEICKRERAVLVATDAIRERLFGSET
                     RQKNTYRIFEEAFAEIERALASGRNVVFDATNVARDRRIQFLKRFRDVSVECHACITPY
                     EIARERVQARKRKIEDKVLEKYTKNFEFPVLAEGFDSLHIVHTPANTGMERAELEQLLA
                     QRPGHDQLFGYLKRSPYFNVMLGYDQENPYHSKTLSEHTHAVLDYINALYEGEHLLEMQ
                     LAALFHDAGKPFCKVWKPNRGYYSYFGHEHVSAGIACHVLKGLGYGDDFILHVVNMVSF
                     HMEILHGGDAGASKIYHLLGDQLLAELYFFAEADTYAK"
     gene            15096..15725
                     /locus_tag="BN6628_RS01400"
     CDS             15096..15725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018754286.1"
                     /locus_tag="BN6628_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA ligase family protein"
                     /protein_id="WP_068613224.1"
                     /transl_table=11
                     /translation="MKVKYPKTMHLPWSRSYTDDDRILRDTDHFAGKEIVITEKMDGEN
                     TTMYQDFIHARSLDSKDHSSRHYVKTLHGGIRYMIPEGYRLCGENVYAKHSLHYTSLPG
                     YYMLFSVWDDRNICLSWDETTAWAEKLGIPHVPILYRGIWSEEAAKACYTKQSKCGGEQ
                     EGYVVRLASEFPYEDFKRSVAKFVRKNHVQTDEHWLSKPIEPNGLA"
     misc_feature    15751..15767
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.77"
                     /tool="antismash"
     gene            16013..16810
                     /locus_tag="BN6628_RS01405"
     CDS             16013..16810
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016993278.1"
                     /locus_tag="BN6628_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_068621832.1"
                     /transl_table=11
                     /translation="MDPKAKKILMNTHWSSGRWREGSFICSDEDFQYAKSKGVMFDPVT
                     ISHDECVQRLSELHERSITKDKVVRAFLHSLSTRKVYWRSALSSYALTHHLPIHSYVQQ
                     PVAGLSYTICGDCTARQLMAKEQYIDEDLNVLNFERVKWGGVRLNWLIYCLMDLEFLAR
                     EEDFEISREDTEILKRMLEAVEACGDKDAARQLEKRWKDVFASNQYERDFVMEIWGYAG
                     LLQSQDDYRKERGRGTDFRSMATWRGEDGLCREQVEFYFGDYL"
     gene            16886..19144
                     /locus_tag="BN6628_RS01410"
     CDS             16886..19144
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018884832.1"
                     /locus_tag="BN6628_RS01410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_068613225.1"
                     /transl_table=11
                     /translation="MKTRAISLINLVFFVPAILLSWFVWNDYSRYMTNINDHLASMKGI
                     YFLDEGRKVVGISDQKDGAYYRAHLFDASTGTLLKETTIRSSFYGELGAVSYQQGGVIV
                     PTYDNSLGLQLNYFRPSGEVDELAQGTLHIPSSMSSGVYSWRGRLIITGETIGSALYMA
                     QVKGGEVGKLLLSSPGHLPARPVRVTDVHGSFTNDKALPIFEVSLKDDRVAFVSGILDK
                     NNKPSVLIKNKDENTFDAEDRAAAQFAKHFGFDNAKLIRTDGDYPGKARFYNANEKRWG
                     AAVPTPKPVYQSRVFLLNDQEVLIAGSTAEDELKGTVLGYVFNQKTGKFTDVTGFLSKF
                     SYEALKNDNMTFHKELDKENLYFVNEDQGAGSYQMKNHDIKIVTNKQVGLWMAGEGGDR
                     ISWRSFWNYVKQGGALIINWVVWLVIPLFMFVGLGMIPRLLMRARARKIAEGQQIPGTI
                     VRMEETGLQVNNQPQVRFTVQFEDDGQMKEVEIKKVISFLSDIKVGDPVIISYNKSKNR
                     AVFVTQEDIREPQKLEVIRNAELRRIEPCGKVKRSQVLQLHFTANGRDYTVPVVQPPGF
                     EYRVGERANLALIQGTARIHSYGNGDGLAGSEQISMQGEVLRVEEYPVSIAGRQLMILE
                     IMMTEGPQRIRKVNSLFVPKGLPVQAGVVIPVVMRRDDYAREARLHKGKQGAAKVTSVR
                     FTGTIGERPLAEITVERNGTTYHISQTIEPVYGVETGDELWIAYDENTREAVIVNYAS"
     gene            19444..20826
                     /locus_tag="BN6628_RS01415"
     CDS             19444..20826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019534562.1"
                     /locus_tag="BN6628_RS01415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_068613228.1"
                     /transl_table=11
                     /translation="MYEEQLNRIRRKLELAAEADPDYQVFGARSHRYKMKQPLQPAELQ
                     QFEQTHGVVLPEDYAAFLTGIGNGGAGPYYGIHPLGKKQSMELDGLAQPSHLHPKVGPS
                     GAGGHSELHETNLDSLSDEEYDQYEARMFQGLLNIGEQGCTYETMLVVTGEHRGKVVYL
                     DLDSYRSFFTYEQNFLDWYERWLDETIASYDSSWFGLRRGGDERELESLYSSTADKHVR
                     IEALQGMLKLPEITDEMAAFLKEQCREESGEVSQWALQVLAKMRFDQAEPLLRQKLNGK
                     DNDARLFALQLIRWYMPQGDQRFAEEIVLLLPLETNIEAFRFMTYILDDAGVDLLQLML
                     PLFNHPLAEFRLQAIYQAGKSTSKEDALPYFTKALEDPDIGVKRIAIQALSNVPEPALL
                     EVYERLLLQHKTGDDYIRSNISRRLQEFAFASMDEVERAVPASLSQVRGMFRASLEPYR
                     RK"
ORIGIN
        1 cagtaagaac agatcggaac tggccgatgt atacggcggc gcagacgtta tggtggctaa
       61 ggtcggaggc atgtgggacg ctctgctcgg tgaagggcgc cgtttctgga acttcacgaa
      121 ttccgatttc cactttaaag tgagcagcaa ccgcaattat tcaagcggct actggcctag
      181 tgagtattca cgaaattata catgggtcga gggcaatact tttaaagatg ttgtagcggg
      241 aatgcgttca ggtaaatcct atgccgtata tggcgatctt atcaatgcgc ttgattttaa
      301 agctgctggt aatggccaac aggccgaaat gggtgggaat ctgcaagtga ccgaagggga
      361 tcttacaacc atcagcatcc gcttcaagag cccggagcac aacaactatg cgccaattag
      421 cccgcatgat acttcagtta cgaataatat caaggttgac catgtcgatc tgatctctgg
      481 agaagtgacc gggaagctca atgagagcca atacgccggt aataccacca atgatacgac
      541 aaaagtcatt aaacgcttta cccaggaaga ctggggacag cccgatgcgg aagggtatta
      601 tacggtttcg tataaggtgc cagcggacac taaccgctac taccggttgc ggggtacgaa
      661 tttgggtaca gacgtacctg gctacaccgt taacggcgag cctgtgcagg ataagtcctt
      721 cgattatagc ggcagtgtaa cgccagagca gaacgaggaa cgcttcaata atattaatga
      781 ccgtaactat acaggcttgt ggttttattc caacccgatc tttgtgaatg ttgcagcgct
      841 cagtgacgag caggccatga acgatacaat tgccaatata acttcaaccc ttggggatac
      901 aagtgccgtg acttccgaca ttcttcttcc ttcggaaggg cttcacggaa ccaagattga
      961 atggaagagc agcaacacgg atgttattcg ccttgataac gataaagcgg tagttacccg
     1021 tccatctgct ggcacaggag atatgcgtgt cacgttaact gcaacggtat cccgtggagg
     1081 taaaagtatg gataagccgt acacctttat tgtaaaagcc tacccgccga gcggtggctc
     1141 gtcaggcaat agtccatcag gcggcagcag cccgtcagac aacagtgcgc caggcatcgg
     1201 cagctccaac aagccgaatg tgtccgtccc aggcggcggg ggaaccgtta cggcgggttc
     1261 aaatggaagt gtaaccatta cacctgacaa gggctaccag gtcaaggatg ttacggtcaa
     1321 cggggtgtcg aaaggggcac tcactcaatt gacaggcctg aaatcttcgg accaagttgt
     1381 ggtgaccttc gagaagcttc cagagcagcc tggaaagcct gagcagcctc agaaacctgc
     1441 tgttactttt agtgatattt cgaatcattg ggcagcttca gcaattaact atgttgtaga
     1501 gcatgaattg ttcacgggta cagcagccaa taaattcagt ccagacacca ccatgacccg
     1561 ggggatgctg gccaccgtga tgcaccgttt agcaggtaag cctgaagcag gggcagcatc
     1621 ccatcacttc caggatgtaa atgcaaatgc ttattaccgt gatgcggtag cttgggcaag
     1681 tcagaataac atcgtccaag gggttaatcg cagccagttt gctcccgatc agccaattac
     1741 ccgggaacag cttgtacaga tcctcttcaa ttatgccaag gctaacaagt taaatatgaa
     1801 tgctaaccaa tccctgtccc cgttcgcaga ctcgggcaaa atttccactt gggcaattga
     1861 tgccatgaag tggtctgtaa gcaatgagct gatctccggc aagggcaacg gcaagcttga
     1921 tccgaagggc gccgtatccc gtgcagaagc cgcagccttg atcaaccgtt ttatgacaac
     1981 ctttaatttg taatcccaaa atctgctccc gcaatgaaag cccggccgtt atggccgggc
     2041 tttctgtttg ctagagctca tccgcgaggc ctagcaaagc gattcccaca atcacgatca
     2101 tcacaacggc gtattgcttg gcattcagcc gttccttgag aaatatccgg gatagtatga
     2161 cggagaaaat gctatatgag gcaatgagag gggctgcaat aatggcattg ctggacatgg
     2221 cgaacacata gaagaattgc cccgtggttt ccaggatggc cgcataacct ttgacacgtt
     2281 cccggaaaag gttgaacggc tgttttttca caaacttgag gtatgtatat gccagtacgg
     2341 cgcagatgaa aaaagtgaat tcataagcga gcagggcggc gtcctggctg atcaggttca
     2401 gttcatccag atagatgccg tcggcgaagg tgccgagccc atcgatcagg cagtacagaa
     2461 tcggaaaggt aatagccatg aagccgattt gatactttct atcgatttgt gtcgaatgat
     2521 tctgaagcgc ctcatgctca gctctctttt ccaagactgc aatgccaaca acgccgcagg
     2581 taattattgc tatacccaat atctcaatga ggctcagatc atgagtgaag aagataaaga
     2641 gcagaatggc cgtaacggct cctgaggaat tctgtacggg agatgcaatg gacagctcca
     2701 tataccttag tccaatataa ccgagggtca tcgacaggat atatagtgcg gagacgggca
     2761 ggtagcgcag catgtcgatg ggattaaagc ttaatccctg aatgagcata taagccgtgg
     2821 cgtgaattcc cataacgagg cccaccacaa tgacgatttt aatatgacta taccggtcat
     2881 gactgtcact gcctttttta taaaagagat ccgcacctcc ccaagctaaa gctgttaata
     2941 aagcaaatac aaaccacata gtcggcgact ccttgtaata aaattcacaa tataagtgat
     3001 acagtgcaag ctttattatt ataagacttc attatgtatg tcaatagcca aaaagagcac
     3061 gtattgaaca gggagtcata tcctgcaata aaaatttcgt aactaagaag aatctttccc
     3121 gtactaagac ttaatatgat tatgcctagt tgaacttgaa ttcgatcatt cctgcccatg
     3181 gagaaacctc cattcccata tagcatatag gtattacatc taatagaaaa tgaggtcata
     3241 caccgaatga atgtcgaatt tatcgatcat gtcgataggg ttatcagttg gctgagcaga
     3301 aggcggctca gtactttgca ttcctttata cacaggtcat ggaaaagaat tatgtgccta
     3361 ccctgatgag agatatccag ttgtggaaaa gagaccatgt atctccccgt ttatgggcgg
     3421 ttgcctcgcg tttaaggaat aaaccggatc cccgggatta ccacagatat ctaggttggc
     3481 ttgagaagac agggggcttg gatgattacc tggatcgaag tgtgtcctat atttatatga
     3541 gggatttggg ccaggttttg gattctcctg atacccggat caggatcaag cgtttagtcg
     3601 ctaacatcaa acgccacctg gttcattcca ccatggcaaa ccaggggggc cagccagagt
     3661 acatgagttt ggcgggggct taccgctggg cacagaggga aggcatagag accaccgtaa
     3721 tctggttgat tagcaagctt aagactgtat cctcaaacct accgaaggag ctagatgccg
     3781 agcaagctca acgcaagctg ctgaagatta ttctgggggt tgtcctgcat gtcattgaag
     3841 aaatggggga tcaagtgccg cctgaggaac gctcaaggca gctggatgaa gctatcaggc
     3901 tgggctattc ctatggtctt acctatcctt tcattgacga tcttctggat tcgcaggtct
     3961 taaccgctca agagaaagaa caatattccc ttgttatccg caccacactg cttaccgggt
     4021 ctgtaccgga agtagataag gggtgggccg gaaataacgt ggatatgatg caatacatcc
     4081 atgcagaact cagggatgct tttgagtata ttaaggacta tcagaagccg gagaccaggc
     4141 agaaattttt tgagcaatcc tatgtgtttt ttcattccca ggagctggac cgcaagaagg
     4201 atctgacgaa tgctaactac tcgaatgaag agctttatat accgatcatt ttgaaatcct
     4261 catcttcccg attgcttgcc cgttccgtaa tcagtgcccc tgtagatgag ggctttgagg
     4321 atcggacctt ctattatggc atctataacc aactggcaga tgattttgcg gatatgcttg
     4381 acgacatgag agacggtgcg gtaaccccct atacctacta tttaaaatac cacgatcagc
     4441 gggtggatct gataaatccc tttgaattat actgggcggt catctcgcat ctgattcata
     4501 acgtgtacca ttccgatgcc aagacccgtg aggttatcct aaaccgcgcc atcaatggtc
     4561 tgaaacgatt taaagacagg atgggtactg agaaatatca tgaaatcatg aacttgctta
     4621 ctcctcgaaa ttcggaattt catcgtctta tccagatgat ggttcgaagg gcagatcacg
     4681 tggatttctt cgacaagctg cttagggacc aggtgattgc cactctgaga aacgaccgga
     4741 aggaacaaga ggacttcctg gagacggtca agatggccca gaatcagatt aaccgcacct
     4801 tgccgatacc gaagcatgac gggatgccac cgatgaaagg gccgcttatt gatgcggcta
     4861 attacagcct tgaaggggat gggaaacgtc tgcggcctgt attgatttgg gtgatgggtg
     4921 tgaacgaata tggactggat ggatcggcaa tcgtgccgct gttgagatcc atggagtata
     4981 tgcatacggc atctttgatt ttcgacgatc tgccgtccca ggataacgcg ttatttcgta
     5041 gagggcgtcc gaccctgcat ctcgtgaatg ataccgccac ggccgaatta accggcctgt
     5101 ttctgattca gaaggcgatt caggaacaaa catcgcttga tcagttcaat gccaagaccg
     5161 tgcttgcctt gatgcagtat tcggcgcaga aggcagaaga cctttgtatg ggacagatga
     5221 tggacctgaa ttccagagga aaagcgttaa ccttggagca gttgaatacg ataagttttt
     5281 acaaaaccgg catagcattt gaggcttctc tggtcatgcc tgctattctt gctgaggcta
     5341 aggaggagga aattgcgggt ctgaagaaat tcgcctatca tgcgggcatt gcttttcaga
     5401 ttaaggatga tttgcttgat ttggaggggg atgcgaacct gctgggaaag cccgtgggca
     5461 aggatgccga gaacaacaac tccacgtttg tatccatcct cggtccggaa ggcgcgacca
     5521 aagagatgtg ggagcactac tgtcttgcta tggaagcgct gaggggaata ccacgcaata
     5581 ttgcttttct gaagcattta ttgaaatata tgattcaccg ggatcgttaa cttcgtatag
     5641 gactttatgc ttacctgtaa atgggaaaat attctcccag agagctcact agccttccat
     5701 tactcccctt ttttctgcat attttgtacc tttctcttcc tggcttttcc agtgtatcat
     5761 gaagagatat gtagaatgtg gcgatatata aggagaatca tatatatgga ttggttgaat
     5821 aagggaattg cagaacgctg gcgggctgaa gggattagat acgcatctga tattaatgaa
     5881 tacgtgcgtg tcggcaatga aacaggatgg ccggaggatt tgaagccgcc ggaagaggac
     5941 cagcgtagaa gcatagcggg ggacatcttg cagatgattc gcgaagctaa ccgatgtggg
     6001 gaaacgaaga agctgcgtga ggaaattccg ccggcttctt ggccgattac ctccgaattt
     6061 cccgataagc tgcagccagt gaaaccgctg gcattcttac aggatggcag cttgctggtg
     6121 cacgccggtt ccgggagtgc agggcaggat taagacggtt ctctcggatg tggaatctct
     6181 agccgatggg gctttcttcg tttcttaacc atatcgattc aatgtttacc ccttctttgc
     6241 ttggcatacg aaaaatcccc tccggtaaac agaaatgagc ccattttaac atgagcactt
     6301 ttcttactgt ctaccttaag gggatagtac caccttttgc attacctctt atttttttgt
     6361 ttttttttaa taattacata cgagcaccat aaaactacaa agacggatgc aagttgccat
     6421 attgaggatc ccgtcatcag tgaatatgta atacttatag catagagcac aactgcaatt
     6481 ataaaaatca acttggagtt catagctcat cccacctttt tccttatttt atcactacta
     6541 attgttattt ggaaatatga aaagtaactt tttgccaaca attgtctaag tcattaagta
     6601 attatattgc aggaaaaatt taggcgatta aaactttggt atttatttgt gcattgaaag
     6661 caggcagtaa ttgaatcaac agcatattca aactgaactt ttggatttga gtgcttcttt
     6721 ttattctatg cagttagttt taatatagtg tctttcattt tttaagttgt tccaacagaa
     6781 agaactataa acatccttta ctcagatatt ttttccttag aatgaaaata taaacctaga
     6841 gacgtcttat aaatctcttt tgtttttaaa ggagtacttt tttaacattg atattattag
     6901 tctaaatggt tctagtctct aaatgtttgt atcaagtaat caatttaaat gtagaggctt
     6961 ttaaacctat tattttgtaa cgatccaaaa gctcaccatc attcgcatag ttacctgcga
     7021 agcatttcat cagctacttc ccgtggataa agaagtactg tatttccttt caattagcac
     7081 tccatccaca atttccacta ttctatccgc aatggagtta ttattttcct catgagatat
     7141 gataatgcac attttattgt taaagatttt ttttatagct tcttccaaaa atgctttaga
     7201 ttccgtatcc aaatttgaag tggcttcatc aaaaatcaat atatccggat ctttagcaaa
     7261 tgcccttaat aaagcgattt tttgtttttg ccctccagag agattgttgg ctttctcatt
     7321 taaaaccatc gagtaaggat ctatatcctt aaacatttta tcctgaaaaa tatccaaaag
     7381 attattaaga tgctctacgc taatatttgg attagccatt tttatatttt ccaaaagtgt
     7441 accagagaac aaaatgacat tttgcgaaac aattcctatg cattttctga gagattctat
     7501 attaatatcc ttaaagttga ttccgtttat ttctattatt ccatcatatt ctctgtacaa
     7561 tcctagcaat atcttaatta tcgtcgattt accagaaccg ttagctcctt gaattgctaa
     7621 aatttcattt ttatctaatg taaaactaat ccctttcaga acgtaatctg ttgctccttc
     7681 gtatttgaac gatacttctt taaactgaat agatgttagc tcttcaattt taattcctat
     7741 ctctttctct tcagtgtcca ttttcaaaat agagcttact ctgtcgagtg ctactaatcc
     7801 aggttgaatt gtcaagctaa atcccgcaat taactgtacg ggagcataga gcagcattac
     7861 atattgagtt agagctacgt aatccccaat agacaactgt ctgcgtacta taagtatccc
     7921 tatggttaga gtaatgataa tttgagatat gtttagtagt aaagatactc cttccgttcc
     7981 catagcagca aatttacttt gctcagtgat ttttcgtgct aatttattca cctgatttgt
     8041 caagtcttta aatgttcttt cttcgttatt gagctgcttt agttcctgta taccttcaat
     8101 tgattcttgc aacttccctt ttgtagttgc attcacttca tataattctc tagattttgt
     8161 ataaatccct ttgagtgatg ctgaagttaa aaaataaaat actggcaaaa aagcaagtga
     8221 aatcatcagt aatatccagc tcttattgaa aatataataa aacgcaccca ctgcagttat
     8281 taaagctgca aaaaagtcaa agatggcgga agagaataat actgacaaag catcgacctc
     8341 atcaatcctt gagagcagat aacctttgtg gttattatca aaatatctca ttggcaaacg
     8401 aagcagatga gaatacatat cttttttgat agatgtagtg aattttacag acaattgagc
     8461 atgtaggatt tgaccaaaat acttaataaa aaacttaatt atgctcagaa acagtaggga
     8521 aaaagatata ctaacaatta ggtaaatgtt ggagcctaga atgccagagt caaaaagcaa
     8581 actggttaca taaggtgtaa acagattaat aatactggtt aaaattgata atagtaaaat
     8641 gctgactaac attaacttag agccaaataa gtatttgaaa ataaaattca tataattaag
     8701 taacattatt atcaaactcc aaaaaaaaca ataattatat tggtcatcaa aggaagaatt
     8761 ttatcagctt cagttcgaat gtccaagata gcaaatttcc ttcttatata aatcattgct
     8821 tagtaactcc tctacagctc tgcaatcgac acaagagaat cgtattttac aggccttgca
     8881 cctttcaatt ttttcaagtg aaaaacgcca aaattcattt aatatttctg gatattgaaa
     8941 taaatctaga atatgagact ttcccaaatc taataatgga tgcttaatca ttgaagggca
     9001 cggaattacc tttctatctg cagttatggc gattacaccc atcaagcaag gatgtaagtt
     9061 tttattaagc ataaagttat aagaaagttt atctgaaaat tgtaccctcg cataagtttg
     9121 cagattactt ttctcatcaa ttaaaagact tgtcgatatg ttactaaagt tataattctt
     9181 gagtttttga ataactgact ccagctgtgt tggagaatcc attacaacat tacaaaaata
     9241 ttcaagctta ttttcaaaga acacctgaaa agtttcgggt gacgtttcta acatactgat
     9301 ttggtggtta ttctcattgg tgcatcttaa aacaaacaac ggattgattt taaattttat
     9361 aaaatggtgg atcatcttgg tatcaagtaa ccgaccatta gtttttaaaa ttatacgcac
     9421 attttcatgt gcattttctc tcgtgtattg aagaagttct aatatggaat ctccaaaagt
     9481 taatgggtct ccaccatgaa aaattaatgt ttgtactgac attttcaata catcagatag
     9541 aaggcttcta taaaactcca tatctaactc agggcttgtt acagttggac aactacaagt
     9601 taggcaacta aatagcttta agcttcgaca acttttacaa tttacctcac atgaggaagg
     9661 taactcaata taacaggtat taagttgcat attactaaca ggtctagcat gtccaattcg
     9721 ggttacttcc tcaacataat aatagtctgc caactccgca agattgcttt ctattagctt
     9781 attaaaaaaa tcatttacca cattcacgtc aaactcattc tttatttctt caatgcacat
     9841 cccctttttt actttattga gaatttcagt atgatgaaca tcaagagaat aatagtcctt
     9901 attggctata tcgtaaatga aagagccgtt attccccact acgattgcac aattagactt
     9961 taatataaga aatttcatat tagtcccctt ctattaagag ttaaaagttt ggaattaatt
    10021 cttccgccaa gataccctct tccataaggc tccaaatctc agcaaactgt ttttgaatat
    10081 gtgttctaat tttttgacaa tttggttcca tataagattt gtcaaattct ccgtctccgt
    10141 ccaatacccc tgcatagcat atatcacaaa gactatgaac tggacaatta ggacaatcct
    10201 tcgttatatt tctttgatag tcctcaatca ttctcattat tgaagatatc tttaaccaat
    10261 gatcaacatc cccaatagac ctagtttggt tcactctttc gcacacatga agattgccac
    10321 ttgtatctac tgctattttc tctcctggta cacacgctcc ggtatatggc agaaaagcag
    10381 ggcgtctact ttgaaagggt atattcctag aacgattcaa tatggagaac atgggtacac
    10441 tgaataatat tttcagaaaa gcatctgctt ctatgccatc cggagatcta acttgatcaa
    10501 tataaactga ttttagttta ttaaacgagt tgatgaactc ctccttttct tctgctgaat
    10561 attgatcata ccaatttgta aaagatgtac caacttgcga tattcttgcg atttttggta
    10621 atatactttg attttctttt agaaagtctc ttagtttcat taaatttgaa cctgtatcta
    10681 tagttattaa taattgacag tattctttaa aataatctgg atacaactct ctaattctac
    10741 ttaagttcct cattacaata tcataggtac ctgaaccatc tttaaatact ctcattctgt
    10801 catgttcatc tctgtctccg tttaaactga tcgatagagc aaaagaatgt ttggctaaaa
    10861 aatgtatttt ttcatcatta agtaatatag cattagttgt agtagaaaat tggactttat
    10921 tatgatattt ttcttttgtg aaactcacta cctctttgat taattcataa ttaagaaaag
    10981 gttctcctcc ataaaatgca atgagtggat tatcgaaagg atttttaaat tttctttgtt
    11041 taaaattttt taaatattta tcaaccgcct tcttagcggt ctccacactc atgaattctc
    11101 ttttatggct tctttggttt tcgtagtttc ctgaatatac gcagtaggta catctaatat
    11161 tacaggcttg tgttgttaaa agaattaatt gacttccact attgtcatcc agataatcct
    11221 ctaattcttt cctattaatc gaagcctcct gtagctgtga atttccaaag atgaaattac
    11281 ttttttcata gtttccttgg aacttcacat tgcttgtatc gtcatcataa tagtatgagt
    11341 ttcctttgtt tgtagtaaag aagaaccctc tgtcactcat aataatcccc ccttaaggta
    11401 ctttataaag agggcatata gaatcaagcc gactcaaaaa gattcgtttc ctaattctat
    11461 atgcctccta caaaatataa gtatattaaa tctcttaaat ttccttatta atcattaatt
    11521 agcatagcta ttgtataaga aagagccagt gacaatagcc aacgctgctg gccctgtttc
    11581 tactccagct gcacaagcaa cgaaacaggg tccagcacaa ctaatagaac aagtccaacc
    11641 actttgcggt gtaacattat tcatttgttc catctttttc cacctccttt cttttgttat
    11701 ttttccactt tcttactaat aaatcaatag tttgagaaaa aattcacata tttgtcaacg
    11761 atcaccacaa tcaaatttta tgtatgtttt tgtcatttga atagttgttt cagttagttg
    11821 aaacgaaccg ctagtgttat agagcaatct gttgttactc ctagctatca aaacctttag
    11881 aagtattact taaggatgta ggtgacgtgg gttcggctgg tcaaccaaga atacataagc
    11941 attcgtgaag tggtgaagga tttggatatt ccatacaaac ctcaaatata tgacattaaa
    12001 gcaattggat acatacagtt tttataagac ctaaattgaa gatatttgtt tgatttgcag
    12061 gggatacgct ccactggaaa aacctcattg gcgaggaagg tatgccgaga acaacaactc
    12121 cacgtttgta tccatcctcg gtctggaagg cgcgaccaaa gagatgtggg aacactactg
    12181 tcttgctatg gaagcgctga ggggaatacc acgcaatatt gcttttctga agcatttatt
    12241 gaaatatatg attcaccggg atcgttaact tcgtatagga ctttatactt acctgtaaat
    12301 gggaaaatat tctcccagag agctcactag ccttccatta ctcccctttt ttctgcatat
    12361 tttgtacctt tctcttcctg gcttttccag tgtatcatga agagatatgt agaatgtggc
    12421 gatatataag gagaatcata tatatggatt ggttgaataa gggaattgca gaacgctggc
    12481 gggctgaagg gattagatac gcatctgata ttaatgaata cgtgcgcgtc ggcaatgaaa
    12541 caggatggcc ggagaatttg aagccgccgg aggaggatca gcgcagaagc attgcggggg
    12601 acatcttgca gatgattcgc gaagctaacc gatgtgggga aacgaagaag ctgcgtgagg
    12661 aaattccgcc ggcttcttgg ccgattacct ccgaatttcc cgataagctg cagccagtga
    12721 aaccgctggc attcttacag gatggcagct tactggtgca cgccggttcc gggagtccag
    12781 ggggaacgct ctacagggct cacgcggggg acctgaccga aattaccgga gcgaattatg
    12841 ccggcagctc gcgggacggc gcgtatgtgg cacttgtgaa tgaacaaggc attcgtgtgg
    12901 tgaaaggtat gactggcgat acggaagggg agcaggtcgc tgtttttcgc tggaaggatg
    12961 ttcagggcag gcttaaagcg gctctcccgg atttggaatc tctggccgat ggggagcatc
    13021 cagaaaggca catggatgag gtgattcctg ttgacggggg cagaagggtg atgctcgtat
    13081 gcggatacgg gatttatctg ctaggcggcg gtgagggtga ggtagaggtt gaactgctcc
    13141 atcctgagct tgccgacttg agagagtacg agagcgagga tacgatcgtg gatatggcac
    13201 acggtgacat atcccccgat ggccgatggc tggcctacgg ctcgcagagc agtgaacatc
    13261 aattgaagga cctgcagagc ggagcggtat atgcttacga gccagcctca agctatccgc
    13321 actttgcccg tttctcggag gacagccgtg aggtgtggtt caatgcgtgc cacttttaca
    13381 acggggcgac ctttaaagtg cctttggcgg aggccgcaca aaagagagag tggggcagcc
    13441 cggaagagtg gctgctgacc aacgaggaaa tgcgtgttta tgcgggagta tctctgcagg
    13501 aaggttatat tcttggtgac gcttacggtt atcttaggtt cattgacagg aagggtcagg
    13561 agatctggcg ttattttgta ggcagtacga tctcgggcat gacattaacg gtggatgaaa
    13621 aggtgcttgc cgtcggcacg tacgggggca tgctgcattt actggatttg aagtgcggcc
    13681 agaagagcga gtacagcatt ggaacggcgg ccattctgga aacggaccgc tggatgctgt
    13741 ggcagaatca ggagcctcta agctggtagc ggaggatgtc ttcggccttc caagctcccc
    13801 caaaacaata aatagtacac ttaagctgga gacagcttgg gaaagacacg taaatttggc
    13861 gaaatcaagc aaactaagcc ttatactcta aagaatcggc gatttaatgt gtttaatcca
    13921 ttagtccgcc gatttttgtt taggccgggg ctctctatat aaattgaact ttagaattta
    13981 ctgatccgag cggagagggc gagtgattct gtaacagggg tcataagaac acttggcatt
    14041 gcagcgcctg agaagtgtaa ccttcgtaag ttcatattat atcgttatat tatctgtaga
    14101 acctgaaagg aggtgatgaa gatgagtgcc attcatatgc tggccggtat cccgggcagc
    14161 ggcaagagcc attatgcgaa ggaaatttgt aaacgtgaac gagcggttct cgttgcgacg
    14221 gatgccatac gggagaggct gttcggaagt gaaacccggc agaagaacac gtaccggatc
    14281 tttgaggaag cttttgctga gattgagcgg gccttggctt ccggaagaaa cgtggtcttt
    14341 gacgccacga acgttgcgcg ggaccggcgg attcaatttc tgaagcggtt tagggatgtg
    14401 tccgtggagt gccatgcctg tataactccc tatgaaattg ccagagagcg ggtacaggca
    14461 agaaaacgga agattgaaga caaggtgctg gagaagtaca ccaagaactt cgagtttccg
    14521 gtgcttgctg aaggctttga cagtctccat atcgtgcata cgccagcgaa caccggaatg
    14581 gagcgggctg aacttgagca gcttcttgca cagaggccgg gtcatgatca gctatttggt
    14641 tatctgaaga ggtctcccta tttcaatgtg atgctgggct acgaccagga gaatccatat
    14701 cattccaaaa ccttgtctga gcatacacat gccgtattag attatatcaa tgccctttat
    14761 gaaggagagc atctgcttga gatgcagctg gcggccctgt ttcatgatgc cggcaagcca
    14821 ttctgcaagg tctggaagcc aaatcgggga tattattcat atttcggaca tgagcatgtt
    14881 tccgccggaa tagcctgcca cgtgctgaag gggctggggt acggcgacga ttttatttta
    14941 catgtggtga acatggtgag cttccacatg gagatcctgc atggaggaga cgccggagca
    15001 tccaagatct atcatttgct cggcgatcaa ctgttggcag agctgtattt cttcgcggaa
    15061 gcggacacgt acgccaaata gaggtgattt aagttatgaa agttaaatat ccaaagacga
    15121 tgcatcttcc ttggtccaga agttatacgg acgatgaccg gatacttcgg gatacggacc
    15181 attttgccgg gaaagagatt gtcattaccg agaaaatgga cggggaaaat acaacgatgt
    15241 atcaagactt cattcacgcg aggtcgctcg acagtaagga ccactcttcc cgtcattatg
    15301 tgaagacgct gcatggaggg atccggtata tgattccgga agggtatcgg ctgtgtgggg
    15361 aaaatgtgta cgccaagcat tcactacact acacgtctct gcctggttat tacatgcttt
    15421 tctcggtatg ggatgaccga aatatttgcc tctcctggga tgagaccacg gcgtgggcgg
    15481 agaagctggg gattccgcat gttcctattc tataccgcgg gatatggagc gaggaagccg
    15541 ctaaggcatg ttatacgaag cagtccaagt gtggtggtga gcaagagggg tatgtggtcc
    15601 ggctggcctc cgaatttcct tatgaggatt tcaaacgctc ggttgccaag tttgtccgga
    15661 agaaccatgt gcagaccgat gagcactggc ttagcaagcc gatcgagcct aacgggttag
    15721 cttaagcaca tttagcggaa aggcatgtgg gtgaaagaat ataacataaa gataaggaga
    15781 gggttatcat gtaattcgta tgcggtttgc agcaaagttg ggtcacatat tgtagtgatt
    15841 tagaaattca aatttgatag ttttctagtt gtatagattt cccatacata gagttaatta
    15901 tgatttggta catagggtat gcgatttttg cgagatatga ggatttaggg ttgatctcag
    15961 gttttaagta gattaaggat cagaaatgaa caggaggcag atgacgatga tgatggaccc
    16021 caaggctaag aaaatattga tgaacaccca ttggagctcc ggccgctggc gggaggggag
    16081 cttcatttgc tcggacgagg atttccaata tgccaaaagc aagggagtca tgttcgaccc
    16141 ggtgacgata tcgcatgacg aatgcgttca gaggctgagc gagctgcacg agcggagtat
    16201 cacaaaagac aaggtggtac gcgcattcct gcacagcttg tcaacacgta aggtctattg
    16261 gcggagtgcc ttgtccagct acgcgctgac gcatcattta cccatacata gttatgtaca
    16321 acagccggtc gctgggctga gttatacgat ttgcggtgat tgcaccgcca gacaactgat
    16381 ggcaaaagaa caatatatcg atgaagactt aaacgtgctt aattttgaac gggtgaaatg
    16441 gggaggcgtg cgtttaaatt ggctgattta ttgcttgatg gatcttgagt ttctcgccag
    16501 ggaagaggat ttcgagataa gccgggagga cacggagatc ttgaagagga tgcttgaggc
    16561 cgtagaagcc tgcggcgata aagacgcagc taggcagctc gagaaacgat ggaaggatgt
    16621 gttcgcctcc aaccaatatg agcgggattt cgtgatggaa atttggggat atgccggact
    16681 tctgcaatct caggacgatt accgcaaaga gcgcgggcgg gggacagatt ttaggtcaat
    16741 ggccacctgg cggggcgagg atggactgtg cagggaacaa gtggagttct attttgggga
    16801 ctatttatga tgatctgtgc aggcggcatg atctgagcta aagctgggaa ggcaagctct
    16861 gcaggtatgg aaggggggaa gacagatgaa aacacgtgcg atatcactca taaacctggt
    16921 gttctttgtt ccggctatcc tgcttagctg gtttgtatgg aatgattaca gccgctacat
    16981 gacgaatatc aatgaccacc tggcgtccat gaaagggatc tatttcctgg atgaggggag
    17041 aaaggtggta gggatttccg atcagaaaga tggagcctat tatagggcgc atctgttcga
    17101 cgcaagcacc gggacattgt taaaagagac tacaatacgc tccagttttt acggggagct
    17161 tggtgctgta tcttatcagc agggaggtgt catcgtacca acctatgaca acagcttggg
    17221 gcttcagctc aattatttcc gcccgtcggg tgaggtggat gagctagccc agggtacgct
    17281 tcatattccg tcttcgatga gctcgggtgt gtattcatgg cgtggaagat tgattattac
    17341 cggtgagacc atcggctcgg ctctgtacat ggcccaagtg aaaggggggg aggttggaaa
    17401 gcttcttcta agttccccgg gtcatctccc ggcgagacct gtccgggtga cggatgtaca
    17461 cggcagcttt acgaacgata aggcgctccc gatttttgag gtgagcctga aagatgatag
    17521 agttgctttt gtcagcggaa ttctggataa gaacaacaag ccttccgtgc tgataaagaa
    17581 taaggatgag aacacctttg atgcggagga tcgggccgca gcccaatttg ccaagcattt
    17641 tggctttgac aatgccaagc tgattcgaac ggatggcgat taccctggaa aagccaggtt
    17701 ctataacgcc aatgagaaga gatggggagc cgcggtgcct acgcctaagc cggtgtacca
    17761 atcccgggtt ttcctgctga acgaccagga ggtgctgatt gccggatcga cagcggaaga
    17821 tgaattgaag ggcactgtcc ttggttatgt gttcaatcag aaaaccggta aatttacaga
    17881 tgtcaccggg ttcctgagca agttttcgta tgaggctctg aagaatgata acatgacttt
    17941 tcataaagaa ttggataagg agaaccttta cttcgtgaat gaagatcaag gggccggttc
    18001 ttaccaaatg aagaaccatg acatcaagat cgtgacgaac aagcaggtcg gactttggat
    18061 ggctggggaa ggcggagacc gaatttcctg gaggagcttc tggaactatg tgaagcaggg
    18121 cggcgcactg atcatcaact gggtggtatg gctggtcatc ccattgttta tgttcgtcgg
    18181 gctaggtatg attccgcgcc tgttgatgag agcaagagcc cgaaaaatcg cggaagggca
    18241 acagattccg gggacgatcg tccggatgga ggagaccggc ctccaagtga acaaccagcc
    18301 gcaggtaagg tttaccgtcc agtttgagga cgacggacag atgaaagagg ttgagatcaa
    18361 gaaggtgatc tccttcttaa gtgacatcaa ggttggggac ccggtgataa tcagctacaa
    18421 caagagcaag aacagagctg tattcgttac gcaggaggat atccgggaac cacagaagct
    18481 ggaagtgatc agaaatgctg agctgcggcg tatcgaacct tgcggcaagg tgaaacgcag
    18541 tcaagtgctc cagcttcatt ttacggcgaa cggccgggac tatacggtac cggtcgtgca
    18601 gcctcccggt tttgaatacc gtgtaggaga gcgggccaac cttgcgctga ttcaagggac
    18661 ggcgagaatt cacagctatg ggaacggtga cggcctggca ggctcggagc agatctcgat
    18721 gcagggagaa gtgctcaggg tggaggaata cccggtctcg attgcaggac ggcagcttat
    18781 gattctagag atcatgatga ccgaagggcc gcagcgaatc cgcaaggtca acagcctctt
    18841 cgtgccgaaa ggtcttcctg tgcaagccgg tgtggtcatt ccggtcgtga tgagacgaga
    18901 tgactatgcg agggaagccc gtctgcataa aggcaagcag ggggccgcaa aagtgacttc
    18961 ggtacgattc actggaacaa ttggcgaacg gccgctagct gagatcacag tggaaagaaa
    19021 cggaacgact taccacatca gccagacgat tgaaccggta tacggggtgg agactggcga
    19081 tgagttgtgg atcgcttacg atgagaatac gcgggaagca gtgattgtaa attatgcttc
    19141 atagtaaatc gccttctgtg cacttgtcta accgattttc aagcgtgcgc ttctaatcgg
    19201 ttcgcaagtg tgcatggagg ggcgaaagct tcgatcccga gtgattctga agaagcggag
    19261 cgtccgcctt tgtctccgaa ataccctact ttgatatcta tttcaaggat ttcggggaca
    19321 acagtggtcg taagaacact cggcatcgca gcgcccaaaa gggtaacttt cataagttca
    19381 ttttatatac ataaaaatat ttggacgcta aattcgggaa cgcgagcagg gggaaaagaa
    19441 tgtatgtatg aggaacagct aaaccggatt cgccggaagc tcgagctggc ggctgaggcc
    19501 gacccggatt atcaagtatt cggggcaaga tcacaccgct acaagatgaa gcaaccgctt
    19561 cagccagctg agctgcagca gttcgagcag acacatgggg ttgttctgcc tgaagattat
    19621 gcggcttttc taaccgggat tggaaacggt ggggccgggc cgtattatgg catccatccg
    19681 ctcggcaaga agcagtctat ggagcttgac gggcttgcac aaccttctca cctgcacccc
    19741 aaggtgggac cgagcggggc tggaggccac tcagagcttc acgagaccaa tctcgactcc
    19801 ttgagtgacg aggaatacga tcaatacgaa gcccgcatgt tccaaggctt gctaaatatc
    19861 ggtgagcagg gctgcaccta cgagacgatg ctggttgtta cgggggaaca ccgggggaag
    19921 gtggtttatt tggatctgga cagctaccgg tcctttttta cctatgaaca gaacttcctg
    19981 gattggtatg aacggtggct cgatgagacg attgccagct atgacagctc ctggttcggc
    20041 ttacgccggg gaggcgacga acgagaatta gagagcctgt attcatccac ggcggataaa
    20101 catgttagga tcgaggcgct gcagggcatg ctcaaactgc cggagattac cgatgagatg
    20161 gccgcatttt tgaaagaaca gtgtcgtgaa gaatctggcg aagtaagcca gtgggcgctg
    20221 caggttctgg ccaagatgag gttcgatcag gccgagccgc tgcttcggca gaagctgaac
    20281 ggaaaagaca acgatgcccg tctgttcgcc cttcagctca ttagatggta catgccgcag
    20341 ggagatcagc gttttgctga ggagatcgtt ctcttgcttc cgctcgaaac gaatatagaa
    20401 gcattccgct ttatgactta tatattggat gatgccggag tggatctgct tcagcttatg
    20461 ctgccattgt tcaaccatcc ccttgcagag tttcgcttac aggctatcta tcaggctgga
    20521 aaatcaacaa gcaaagagga tgcgcttccc tatttcacca aggctctgga agacccggat
    20581 atcggggtga agcgtatcgc catacaggct ttatcgaatg tgccggaacc ggcactgctt
    20641 gaggtgtatg agcggctgct gctgcagcac aagacgggtg atgattatat ccgctctaat
    20701 ataagccgga ggctgcaaga gtttgctttt gcttcaatgg acgaagtgga gcgggcggtg
    20761 cctgcatcct tgtcccaggt gagaggcatg ttcagagcca gcctggagcc ttatcgcagg
    20821 aagtagaaat aacggaggtg gcacgacgat gacagaacgg attccttgcg aaacggcagg
    20881 ctgcaagtca accatcctgc ccgccaccgc cgccaaaaca ggcggctact gcatgccctg
    20941 ccatcaggag caggagcgtc agaagagaca ggcttatatt gaacagcatc gcagaacggt
    21001 gaacttatat gagggcctca ccgacccggt ggaaatctta aaaatcatgc atgccaaggc
    21061 gtcgtatgac ccgctggttc aatatgttcc atatccgctg agcagggagc agctgtacct
    21121 ggatctaacg gccgaacagg cggtgaaaat gcaggagtat gccgtgaagc atttgactga
    21181 aggaggcaag gacaccgccg agaatatatt gttatcgctg gtttgctacc ggaatgataa
    21241 cattgctggg gtcctgccgg accttatgga acatgggata tattatcccg ttatattgta
    21301 caaggacgca ccttcgggaa tgcgggaccg cctgcttaga caagtggatt gggatgaaga
    21361 gaaccgcaat gatatcctgc
//
