LOCUS       NZ_LN850107            21041 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Alloactinosynnema sp. L-07 isolate Alloactinosynnema sp. L-07
            chromosome I.
ACCESSION   NZ_LN850107
VERSION     NZ_LN850107.1
KEYWORDS    RefSeq.
SOURCE      Alloactinosynnema sp. L-07
  ORGANISM  Alloactinosynnema sp. L-07
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2015) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900070365.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:00:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,999
            CDSs (total)                      :: 6,934
            Genes (coding)                    :: 6,831
            CDSs (with protein)               :: 6,831
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 30 of 103
            Pseudo Genes (incomplete)         :: 83 of 103
            Pseudo Genes (internal stop)      :: 1 of 103
            Pseudo Genes (multiple problems)  :: 11 of 103
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:22:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4675337
            Orig. end                         :: 4696378
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN850107.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="27"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11041
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(343..358)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.92"
                     /tool="antismash"
     gene            916..1680
                     /locus_tag="BN1701_RS20790"
     CDS             916..1680
                     /NRPS_PKS="Domain: Thioesterase (20-227). E-value: 6.1e-47.
                     Score: 152.9. Matches aSDomain:
                     nrpspksdomains_BN1701_RS20790_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222578.1"
                     /locus_tag="BN1701_RS20790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase II family protein"
                     /protein_id="WP_157368133.1"
                     /sec_met_domain="Thioesterase (E-value: 2.4e-44, bitscore:
                     150.9, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-11, bitscore:
                     43.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASTDLWIRRFHPAPAAAHRLVIFPHAGGSASFYFPFSKALSPD
                     VDVLTVQYPGRQDRLAEPLIDSVTGLADALTEVVRPWMDRPVTFFGHSMGASVAYELAL
                     RLPPSRLVVSGRMAPSTWREDYIHTLDDAGVMAKTRELAGTEAEALDDPEIMAMVLPTI
                     RNDYRAAELYRGDPRSQVDAPILAMTGDADPRTTSDEVKAWAEHTTGTLDIEVYPGGHF
                     FLIDNVLAIGAVLLASPPGTRARPPQGDVSGT"
     aSDomain        976..1596
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1701_RS20790_Thioesterase.1"
                     /evalue="6.10E-47"
                     /label="BN1701_RS20790_Thioesterase.1"
                     /locus_tag="BN1701_RS20790"
                     /protein_end="227"
                     /protein_start="20"
                     /score="152.9"
                     /tool="antismash"
                     /translation="RLVIFPHAGGSASFYFPFSKALSPDVDVLTVQYPGRQDRLAEPLI
                     DSVTGLADALTEVVRPWMDRPVTFFGHSMGASVAYELALRLPPSRLVVSGRMAPSTWRE
                     DYIHTLDDAGVMAKTRELAGTEAEALDDPEIMAMVLPTIRNDYRAAELYRGDPRSQVDA
                     PILAMTGDADPRTTSDEVKAWAEHTTGTLDIEVYPGGHFFLIDN"
     CDS_motif       1168..1233
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN1701_RS20790_0001"
                     /evalue="9.70E-08"
                     /label="NRPS-te1"
                     /locus_tag="BN1701_RS20790"
                     /protein_end="106"
                     /protein_start="84"
                     /score="24.5"
                     /tool="antismash"
                     /translation="RPVTFFGHSMGASVAYELALRL"
     gene            complement(1749..4511)
                     /locus_tag="BN1701_RS20795"
     CDS             complement(1749..4511)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="BN1701_RS20795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_054051362.1"
                     /transl_table=11
                     /translation="MALVERNEELRTLNRLFADCARNRGQVALISGGVASGKTELLHTF
                     AEHAAGKGATVLTATGSRAEHSLAFGVLKQLASAQTLPEAVAANVASLLSGDTDAARPD
                     PVSIGRSRALILEGLCAALMEAAKSTLVVLCVDDVQFADGPSLQAVLYLQRRMRFARVM
                     IILTEWALPRPTRAVFRAEVTRQPNTTHLRLAPLSKRGVEDLLRAELDTSTARTLAPVH
                     HALSGGNPLLATALIEDFRAATRAGGGREKEMAVGQAYGHAVISCLHRWEPAMLEVARG
                     LALLGDAGTPALVGRLVDMTAEAAGSVLEVLELAGLLDGGRFRHPVAKAAVLHGLGKAD
                     RAARHLRAAWLLHHDGADAAQVADHLVAADQADGPWAVAVLRHAAQEAQVADRLDLAMA
                     RLDLAARSCSDETEHADIVTQLLRVEWRENSAAAERHLTPLLDARASGTLADHNAVHLA
                     KFLLWYGHTEDLAGTLAGLAAAASKPDHPAAAYLGLVVRWLAFVTPGATERIKSMPLPS
                     GKDDPWSRAGAVLDAIRAGKADSETARAAEYILQSCRLGEQAFGAQLSALAALIHADRI
                     DRAATVCEALLAEATNRRAVTWQAVLGGLRGEIALRQGDLPAAAEYARVAADAVSAQGW
                     GVVMGSVTAVRVAAATAMGDHQLAATLLRQPVPESVFQTQFGLQYLYARGAHYLATDRP
                     HAALGDFQRCGELMARWSVDLPALAPWRVGAAQAQLALGNREAARTLVSEHLALPGCRG
                     PRNRGIAMRILAATVDATRRVSILAESVDLLHAGGDRFELARALTDLSQAHQDSGACEK
                     ARAVARRALQMAKRCQAEPLSRDLRPAREAEPYPADAESLSMDVLSEAERRVAVLAALG
                     HTNREIGGKLYITVSTVEQHLTRVYRKLKVTKRTDLPAGLPRQLMAEDR"
     misc_feature    complement(4266..4268)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4573..4586
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(4574..4587)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.53"
                     /tool="antismash"
     misc_feature    4613..4626
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(5064..5078)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.52"
                     /tool="antismash"
     gene            5179..7293
                     /locus_tag="BN1701_RS20800"
     CDS             5179..7293
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="BN1701_RS20800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_054051365.1"
                     /transl_table=11
                     /translation="MWEPDLPRLVSLLADPARHHEAAALLAKVPWIFGAAGLRRWIKAA
                     IDHGEPPGAIAARLTTHNRAVVLRAMAPLVADGHYRPTAARALLLALGGARSAPPPPRD
                     GGYGQAPVDPRPYWERPRPDPEWRQWPPGPYPGWQTGPPLNPGRPLTPSDPGYPIVPPF
                     DPAEPDPEQTGAFPIPEGPEPPTTREAWPALDFPAAVAADERFDIDVGIGPRQDIELFG
                     TGSFTVPSTSVELEVVLMYDPAAFAPVGWANPIRLTVTPTRPYPLATVGMTALGGPNLR
                     TRRDIGASFYVDGGLRGYASRGIEVTGTPSGVVPLFDGGLLDIGPLLAQDAPDLVVVVE
                     RGEDLRGQTLLWSTRTTLPGVPAAPGPFRSEIGEDPAAFARRIRLDIGAFGGDARGTTL
                     KLIGVGRAIADHIPEEVRAALTAAAAARAPEPATVLLLSSEPHVPWELAVLDPPPPGSP
                     FLGSAMAIGRWVLAKSRPRPTPPTQVRADRHTVVTARYEGVAGWSRLPFAEAEAERLRL
                     AYPPADEIEPLHSAVLDCLEAGPVGGVLHFALHGRYDPENAQDGLVLLAPSDADPTRLV
                     PRFLQPDQVAALEFTTAPFVFLNSCQVGAAGEVLGDYSGLAKAFLAAGAAGVVAPLWNV
                     NDEAAGALADSFYRAAYGPESLAPAEFLRRARSQVTRTDFPAWPATTLAYQFFGHPRLR
                     LRRDKGANHG"
     gene            7286..8758
                     /locus_tag="BN1701_RS20805"
     CDS             7286..8758
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS20805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="triacylglycerol lipase"
                     /protein_id="WP_054051367.1"
                     /transl_table=11
                     /translation="MAEPLRPDGTAVRVGDIVVVSPGLTGRVEVLPPGSEGMRAAEDAR
                     AVLLAALAREGFSEQLTVRLIDPVEVPELASGTSRATSLGEPAITVEVPGPGAGLGQLI
                     LAADEDGALSWHLPDDIDPVDVPDRGGDRRTYTFVRAVAPVDPGASRGLIGAVGSKLLK
                     VLVFPLIDPVLGKVGDHFVSRWEQHNRPVRLRQFTVGGHRESSAASVDWSSLSAGPALL
                     FLHGTGSQSHTGFHGVSDEVLSTLHTRYGGRVFAYDHHTIATDPVANARSLVAQIPVDA
                     GLRLDIVAHSRGGLVGRVLCELPGEIGLTTERMSVRTLVMVATPNAGTPLCDPAHVAKW
                     LDRMTNLLQWVPDNGITDMLDVVLTVVKQVAVGAFRGLSGLMSMDPKGSFLERLNQPSA
                     HSVAYRALASNYDPPKGSSLLRSARNVATDSVFGSAHNDLVVPTDGVFAANGAFGFPVG
                     EVELFDAEVGVDHSGYWTQPRFAAAVDRWLVG"
     gene            complement(8766..9506)
                     /locus_tag="BN1701_RS20810"
     CDS             complement(8766..9506)
                     /NRPS_PKS="Domain: PKS_KR (3-162). E-value: 1.3e-13. Score:
                     43.2. Matches aSDomain:
                     nrpspksdomains_BN1701_RS20810_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332574.1"
                     /locus_tag="BN1701_RS20810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_054051368.1"
                     /transl_table=11
                     /translation="MGPVVILGGRSEIGVAVARRLAERGARTVVLAARRSNDLKAEAAS
                     VRAAGATTVDQIEFDADALDTHRPVLDGIVAEHGPIDTAVIAFGILGDQKRAETDAAHA
                     VAVVHTDYVAQVAILTHLAAMMREQGRGTIVVYSSVAGMRVRKANYVYGSAKAGLDGFT
                     CGLTDALAGSGVRVLLVRPGFVIGRMTDGMTPAPFSSTPDQVAEATVRALAKGRQEVWV
                     PGVLRPLFALLRLLPRPLWRRMPR"
     aSDomain        complement(9021..9497)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1701_RS20810_PKS_KR.1"
                     /evalue="1.30E-13"
                     /label="BN1701_RS20810_PKS_KR.1"
                     /locus_tag="BN1701_RS20810"
                     /protein_end="162"
                     /protein_start="3"
                     /score="43.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVILGGRSEIGVAVARRLAERGARTVVLAARRSNDLKAEAASVRA
                     AGATTVDQIEFDADALDTHRPVLDGIVAEHGPIDTAVIAFGILGDQKRAETDAAHAVAV
                     VHTDYVAQVAILTHLAAMMREQGRGTIVVYSSVAGMRVRKANYVYGSAKAGLDGF"
     CDS_motif       complement(9402..9494)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN1701_RS20810_0001"
                     /evalue="2.90E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BN1701_RS20810"
                     /protein_end="35"
                     /protein_start="4"
                     /score="23.1"
                     /tool="antismash"
                     /translation="VILGGRSEIGVAVARRLAERGARTVVLAARR"
     misc_feature    9576..9590
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.23"
                     /tool="antismash"
     misc_feature    complement(9578..9594)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    complement(9680..9692)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            10001..11041
                     /locus_tag="BN1701_RS20815"
     CDS             10001..11041
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073756.1"
                     /locus_tag="BN1701_RS20815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_054051370.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.2e-62, bitscore:
                     207.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPTEVITGFRSARAVLSQSRSLLDPAIRAAVDSLPATMRRIAGY
                     HFGWWDEHGGPVHADSGKAIRPALVLTSAEAVGGSPRDAVPAAVAVELVHNFTLLHDDV
                     MDGDRTRRHRPTAWTVFGLGPAILAGDSLLTLAYDVLAATGHPRAQDASRVMSAAVLAV
                     QEGQATDLAFEKRADVTLAECVRMAEGKTGALLGCAAAVGALFGGGGAPQVDHLRRFGE
                     RVGLAFQLVDDLLGIWGDPTATGKSVYSDLESRKKSLPVVAALSSNTPASRELATIYHR
                     RTPLSAAELVRAAELIERAGARTWAQAHADGVLTDALTHLDQAAPAPRAAAELTALAHL
                     TVRRDH"
     gene            11060..12223
                     /gene="ispH"
                     /locus_tag="BN1701_RS20820"
     CDS             11060..12223
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685791.1"
                     /locus_tag="BN1701_RS20820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_054051372.1"
                     /transl_table=11
                     /translation="MPDPTAPVTVADHLVGDDTLPCPAAPLIEGTLRRQGKSTRRGPLT
                     TGQATAWVSLSRDTAIAVDSQTAHNALAHWIAVSGPRRILLAAPRAFCAGVERAIDIVD
                     RALEDGPVHVRKQIVHNVHVVNELSARGAIFVDELDAVPDNATVVFSAHGVAPSVREDA
                     GRRGLQVIDATCPLVAKVHAEAIRFAHRGDTILFIGHAGHEETEGTLGEVPDRTILVQS
                     AAEAATVTVPDPSRVAYLTQTTLAVDETAEIIDVLRARFPDLKGPGSDDICYATTNRQD
                     ALLAIAADSDLVLVVGSANSSNSQRLVELANRQGTPAHLIDDAAGIRSEWLEDAHTIGI
                     TAGASAPPTLVDEVVAAIGGLGTITVTEYETARETIHFTLPGQIRRD"
     gene            complement(12210..12671)
                     /locus_tag="BN1701_RS20825"
     CDS             complement(12210..12671)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670979.1"
                     /locus_tag="BN1701_RS20825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_231949664.1"
                     /transl_table=11
                     /translation="MDVMEATRVQATTAAPELYRKLLELHTAADRAAVDAGLERRLLEL
                     VRIRASQLNGCAFCVDLHSTAAVEAGETPRRLHAVTVWRDTPFFTSRERAALALAESMT
                     LLSESHVPDEVYAVASTEFDQAELACLMWTLTVINAFNRLGVAGRLSPV"
     gene            complement(12662..14248)
                     /locus_tag="BN1701_RS20830"
     CDS             complement(12662..14248)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (32-429). E-value: 5.2e-61.
                     Score: 198.3. Matches aSDomain:
                     nrpspksdomains_BN1701_RS20830_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674221.1"
                     /locus_tag="BN1701_RS20830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_054051375.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-53, bitscore:
                     180.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTDLGTLFDDLVDRGVSTVVELSRPLDIAPDHGTTYDVGELAA
                     LVRGAAGWLHAAGVRPGDRVAVVKENHWDYVLLACAAARVGAVPALLSDHLTPETLQLL
                     LKRLDPALLVTTHAVLDHARDNETDLMGFARRTLTLDGPHPGALDLDRLRGHEPPRPVS
                     RDPDDPLVVNHTSGTTGTPKLVMHSTRTLIHGLAATEAARLPVVSSKPTDTVCSALAYC
                     HGRAIPWTASVLWLAPRKVVVIADADGAEPVLRAHPPTTLEALPSIFVRWQPLAERADN
                     PFRDVRLYVSTFDAMHPPTVRAFLGATARRPLWVQVWGQTETGPLTFRFLTRRSVAERD
                     ARHPSTRNLGRPVPGRMRLRVVDPRTFRPVPAGQPGLVLARTKVRCLGYVGEQERWDAK
                     VVGGWWNTGDVGVRTRTGAYLLLDREVDVIPGQSCVELEDVIEDRLPSVVECVILGTPG
                     ELPVPVLVTDGGALDRRGWAHALRDLPALADPIVLTWDEIPRTGTGKVRRMELRTLIRR
                     GHDTFGSGRWT"
     aSDomain        complement(12962..14152)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN1701_RS20830_AMP-binding.1"
                     /evalue="5.20E-61"
                     /label="BN1701_RS20830_AMP-binding.1"
                     /locus_tag="BN1701_RS20830"
                     /protein_end="429"
                     /protein_start="32"
                     /score="198.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DHGTTYDVGELAALVRGAAGWLHAAGVRPGDRVAVVKENHWDYVL
                     LACAAARVGAVPALLSDHLTPETLQLLLKRLDPALLVTTHAVLDHARDNETDLMGFARR
                     TLTLDGPHPGALDLDRLRGHEPPRPVSRDPDDPLVVNHTSGTTGTPKLVMHSTRTLIHG
                     LAATEAARLPVVSSKPTDTVCSALAYCHGRAIPWTASVLWLAPRKVVVIADADGAEPVL
                     RAHPPTTLEALPSIFVRWQPLAERADNPFRDVRLYVSTFDAMHPPTVRAFLGATARRPL
                     WVQVWGQTETGPLTFRFLTRRSVAERDARHPSTRNLGRPVPGRMRLRVVDPRTFRPVPA
                     GQPGLVLARTKVRCLGYVGEQERWDAKVVGGWWNTGDVGVRTRTGAYLLLDREVDVI"
     CDS_motif       complement(13685..13735)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN1701_RS20830_0001"
                     /evalue="5.90E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="BN1701_RS20830"
                     /protein_end="188"
                     /protein_start="171"
                     /score="15.9"
                     /tool="antismash"
                     /translation="VNHTSGTTGTPKLVMHS"
     gene            complement(14245..15018)
                     /locus_tag="BN1701_RS20835"
     CDS             complement(14245..15018)
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685771.1"
                     /locus_tag="BN1701_RS20835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_054051378.1"
                     /transl_table=11
                     /translation="MAETAVRYVFGTSFEREGERLRLGESLWDKGTKATLADLDVGPGW
                     RCLEVGAGRGSIAAWLAGRGAEVTAVDLDVSRLVGLRGVDVRELDIGADVLPGDFDLVH
                     GRLVMQHVGDRPAAVAALCRSLRPGGHLVLEDTDTTSLFSHANGPFHPEVKRAAYDVMA
                     DAGYHPRCGLLDVDLVEAAGLVDVRAVGRAEVVRGGSDGGRWFALWLAHLRPAMLARGT
                     VSEVDIDRAVADLMDTRHRWLSQVMVTVVGRKDTG"
     gene            complement(15011..16339)
                     /locus_tag="BN1701_RS20840"
     CDS             complement(15011..16339)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003091357.1"
                     /locus_tag="BN1701_RS20840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_054051380.1"
                     /sec_met_domain="DAO (E-value: 4.5e-08, bitscore: 31.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADLDVAIVGAGISGLALAHRLRAAGRSVHVFESSPHVGGRMRT
                     VRREGYVIDTGAEMVGTHGYDATWRLAGELGLSQADAPLLGTPLAMWREGVAHPGVGDL
                     GGLIKGAGMSVSGRASLAKLMVGSGLRKRSYDVDRPDRTPLGSTTVRELARRYHPDVHD
                     YLLQPMAGGFFGWDTERAAAGPLMSHLLAVGPTRTFRTWRHGMDTLARQIAARVDVSTG
                     VTVHEVVAGERDATLVVDGAPLSARTVVLCVPAPVAAELHADAPDFVRACQFRPMVKVI
                     CLLDRPIEPIGGSPAWGIAVPSVENPAFAGLLIDHRKPGRAPAGRGLVTLFAGAAVADG
                     LIDAPNEEVSDLLMSHAARYLPELASACRVSVVVRYRHGLPMPTAAALDEYRDFLHRPV
                     STVEYAGDWCVLRPSSEGAIRSAEMTADRLLVGSDSALAVFGG"
     gene            complement(16336..17274)
                     /locus_tag="BN1701_RS20845"
     CDS             complement(16336..17274)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685769.1"
                     /locus_tag="BN1701_RS20845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_054051382.1"
                     /transl_table=11
                     /translation="MTAILTAAPGRVGAYARLAKLDVWDYYLALPLAWSLLGPALWFDP
                     RVLATLALFGVGTVFVVASAVAFDDVTGFVDGSDGANYGPNASARKLARKPLLTGELTV
                     VDAVRFGWATAGIGAVCWGVCVAAAPFALLWTVGLAVLCLVTAVQYSWGLKISYRGWQE
                     VFLAGFGTGLVLCAVGFAQGAITGFGIVQAVLFGLGPLLFGVYSNTRDADGDAAVGRPT
                     AAVLLSATGNRLFIAALSVAEIAVIVVSAGLGAAPWWFALAMMPAVLLRIAQLRRGVGI
                     GDLLAARTLGLRAHRLTFVLLFAINVLGGWL"
     gene            complement(17271..18404)
                     /locus_tag="BN1701_RS20850"
     CDS             complement(17271..18404)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685768.1"
                     /locus_tag="BN1701_RS20850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_054051385.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-99,
                     bitscore: 332.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPSLPFFPPDLFDDDRELLLDTVRRVGLAEEQKFILGASTARF
                     ESALRDQLGAADVVACGSGTTALMLILRAMDIGPGDEVVVPAFGCAPLAASVVNVGATP
                     VFADVHPWTMVVEPYEVEESITSRTAAIMPAHMFSVMADMPTMRALADRHEVRLIEDSA
                     VAQGAVLDGTPAGRWGEAGVFSFVQVKTFGSIGEGGAVVTDDPEIAARVRMLRNHGQDG
                     KQRFVHHVVGFNSRFDEIMAEFQLHRLAGLDARLERRAQIADYYTERFTPLAERGIQPP
                     PPGREGRCYYVYSLLADRRDHLKRHLAELGIGTHVYYPTPLPAQPAFAEYAARDRFWPH
                     AELASARILALPIYPHLTDAQVESIADAVCAFPGGSR"
     gene            complement(18401..19597)
                     /locus_tag="BN1701_RS20855"
     CDS             complement(18401..19597)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018685767.1"
                     /locus_tag="BN1701_RS20855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_054051387.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.2e-111,
                     bitscore: 370.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.7e-07, bitscore:
                     27.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHAATLTGPGAGSAASAPSVPFFTQAASFAAVWPKIEANLNAMV
                     EGGKYSHGPLVAEFESALAEYTGAAHVIGVNSGTDALVLLLRAAGLRPGEEVVVPAFSF
                     VASASSVALAQGRPVFVDIDPVTYAMDPDAVPEVITERTRMIMPVHLFCQLADLSGITE
                     VAQRYALTVVEDSAEAIGMRWGGTHAGLHGAGGVLSFFPTKTLGALGDAGAVITNDPRV
                     GEVAAALRHHGRFGRTLDHFPGISNETVLPGLNSKMDDLQAAVLLAKLATLDADIARRA
                     VLAAAYTERLADRPGVLRLPTVVKRQADTTAVFYVYLIEVERRDDLVAHLAANGVTTET
                     YYPVPLHRQPCFAELGHRAGEFPNAEAACAHAVALPLYPDLTESQVDRVCELIKGFFR"
     gene            19809..20780
                     /locus_tag="BN1701_RS20860"
     CDS             19809..20780
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013567.4"
                     /locus_tag="BN1701_RS20860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_054051389.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.7e-07, bitscore:
                     28.5, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSLVVGLGRAGTALHLPVLRRLRPHQPVVAFDPHRTLDLPGVT
                     ATDSLTHAASITDPASTVVHLCTPPAARVAPLTELAELGFRRILVEKPLAANSVELAEI
                     LRLRDAAGLDLLPVGQWRSSELTRRLRATLAAGNLGRARSITIVQTKPRFGRAGDDHPT
                     AFDVELPHSVLLALLLAGPAKVTAATCSDMLLGDTVHPAMGGATVQLRHDSGIVTEIRT
                     DLTSPVRERRVTVDLDGGTLVGHFAVSDADDHAQLRVNTQGQQLRSVFADDSLGAFLRL
                     AYSHFAGEERIADEPETGVAVVELITAAKRRAGLAVAAGVPA"
     misc_feature    complement(20823..20837)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 tgcccagcgg gtgaccgagc tcggcccgcc gctcggccca cagggtcgct acctccctgg
       61 ccagcccgcg catcctggcg aatgccttgg cccgctccgt ggtgctgacc gcgccgcgcg
      121 cgtcgaggac gttgaaggtg tgcgagcact tgagcacgtg gatgtgggcg ggcaccggca
      181 ggcgcaggtc cagcagcctg cgcgcctcgg cggcgtattc ctcgaacagc cgccgctgcg
      241 agtccacatc ggcgtcgtcg agatagaacc tgctcatctc gtactcggcc tgcccgaaag
      301 cctcgccata ggaaattccc ggcgcgtagg cgatgtcggc gaaatggtcc acaccttgca
      361 acgccatcat gatgcgttcg acgccatagg tgatctcgac cgaaaccggg tcgagcgtca
      421 ttccgcccgc ctgctggaaa taggtgaact gggtgatctc cagtccgtcg agccacacct
      481 cccagcccag tccccacgcg ccgagcgcgg gcgaggccca gttgtcctcg acgaaccgga
      541 tgtcgtgggc gcgcacgtcg atgcccaggg cctgcaggct gcccaggtac agctcctgcg
      601 ggttgcccgg gtccggcttg aggatcacct ggaactgggt gtgggtctgc aggcggttcg
      661 ggttctcccc gtaccgggcg tcgtctggcc gcacactggg ctccacgtag gccacccgcc
      721 acggctccgg ccccagcacg cgcagcacgg tcgccgggtt gagggtgccc gcgcccacct
      781 cggtgttgaa cggctgcacc accatggcgc cgcgctcggt ccagtacctg gtcaacgcga
      841 gcaacgcgtc ctgcatggtc agcacagtgc tacctcatct acgaacctgg atgggatgcg
      901 ggcagtctag tgtctatgtc tgccagcacc gacctgtgga tccgccgctt ccatccggcc
      961 cccgccgccg cacaccgcct ggtgatattc ccccacgcgg gtggctcggc cagcttctac
     1021 ttcccgttct ccaaggcgct gtcccccgat gtggacgtgc tcaccgtcca atatcccggc
     1081 cgccaggacc ggctggccga gccgctgatc gactccgtca ccggtttggc cgatgcgctg
     1141 accgaggtcg tccggccatg gatggaccgt ccggtcacct tcttcggcca cagcatgggc
     1201 gcctcggtgg cctacgagct ggccctgcgg ctgcccccga gcaggctggt cgtgtccggg
     1261 cggatggccc cgagcacgtg gcgtgaggac tacatccaca cgctggacga cgcgggcgtg
     1321 atggccaaga cccgcgagtt ggcgggcacc gaggccgagg cgctcgacga ccccgaaatc
     1381 atggcgatgg tcctgcccac gatccgcaac gactaccgcg ccgccgagct ctaccgcggc
     1441 gatccaaggt cccaggtcga cgccccaatc ctggccatga ccggcgacgc cgaccccagg
     1501 accacatcgg acgaggtcaa ggcatgggcc gagcacacca ccggaaccct cgacatcgag
     1561 gtatacccag gcgggcactt cttcctaatc gacaacgtgc tagcaatagg agctgtgttg
     1621 ttggcgtccc ctccagggac gcgcgctcgg ccgcctcaag gtgacgtttc gggcacgtga
     1681 acacgccaga cttcgtcggc gcattcacgc acccgaaacg tcaccgcggc cgagcggtgt
     1741 tggtgcggct agcggtcctc ggccatcagc tgccggggga ggccagcggg caagtcagtc
     1801 cgtttggtga ccttcagctt ccggtagacc ctggtcaggt gctgttcaac agtgctgacc
     1861 gtgatgtaga gcttgccgcc gatctcgcgg ttggtgtgac cgagcgcggc cagtaccgcc
     1921 acccggcgct cggcctcgct cagtacgtcc atgctgaggc tctccgcgtc ggccgggtag
     1981 ggctcggcct cgcgggcggg ccgcaggtcg cggctgagcg gctcggcctg acagcgcttg
     2041 gccatttgca gcgcccgccg ggccaccgcc cgcgccttct cgcacgcgcc ggagtcctgg
     2101 tgggcctggc tcaggtccgt cagggccctg gccagctcga accggtcgcc gcccgcgtgc
     2161 agcaggtcga ccgactcggc caggatggac acccgccggg tcgcgtcgac cgtggccgcg
     2221 aggatccgca tggcgatccc gcggttgcgg gggccgcggc agccgggcag cgccaagtgc
     2281 tcggagacca gcgtcctggc cgcctcccgg ttgcccaggg cgagctgggc ctgagcggcg
     2341 ccgacccgcc acggggcgag cgcgggcagg tcgaccgacc agcgcgccat cagctcgccg
     2401 cagcgctgga agtcgccgag cgcggcgtgc gggcggtcgg tggccagata gtgcgcgccc
     2461 cgcgcgtaga ggtactgcag gccgaactgg gtctggaaga ccgactccgg caccggctgg
     2521 cgcagcagcg tcgcggccag ctgatggtcg cccatggcgg tcgccgcggc gacgcgcacc
     2581 gccgtcaccg agcccatgac cacgccccag ccctgcgcgg acaccgcgtc ggcggccacc
     2641 ctggcgtact cggccgcggc gggcaggtcg ccctggcgca acgcgatctc cccgcgcagc
     2701 ccgccgagca cggcctgcca ggtgaccgcg cgccggttgg tggcctcggc cagcagcgcc
     2761 tcgcacaccg tggccgcccg gtcgatgcgg tcggcgtgga tcaacgcggc cagcgccgag
     2821 agctgggcgc cgaaggcctg ctcaccgagc ctgcagctct gcaggatgta ctcggcggcc
     2881 cgcgcggtct cgctgtcggc cttgcccgcg cggatggcgt cgagcaccgc tccggcgcgg
     2941 ctccacggat cgtccttgcc cgacggcagc ggcatggact tgatccgctc cgtggcgccg
     3001 ggggtgacga aggccagcca ccgcacgacc aggccgagat aggccgcggc cgggtggtcc
     3061 ggcttcgacg ccgcggcggc caacccggcc agggtgcccg ccaggtcctc ggtgtggccg
     3121 taccagagca ggaacttcgc cagatgcacg gcgttgtggt cggcgagggt gccgctggcc
     3181 cgcgcgtcga gcagcggggt caggtggcgc tccgcggcgg ccgagttctc ccgccactcc
     3241 acccgcagca gctgggtgac gatgtcggcg tgctcggtct cgtcggaaca ggaccgggcg
     3301 gccaggtcaa gccgggccat ggcgaggtcg agccggtcgg cgacctgcgc ctcctgcgca
     3361 gcgtggcgca gcaccgccac cgcccacgga ccgtcggcct ggtcggcggc gacgaggtgg
     3421 tcggcgacct gggcggcgtc ggcgccgtcg tggtgcagca gccaggccgc ccgcaggtgc
     3481 ctggcggccc gatcggcctt gccgagcccg tgcagcacgg cggccttggc caccgggtgc
     3541 cggaagcggc cgccgtcgag cagaccggcc agctccagca cctccagcac cgacccggcg
     3601 gcctccgcgg tcatgtcgac aagcctgccg accagcgccg gggtgcccgc gtcgcccagc
     3661 agcgccaggc cgcgggcgac ctcgagcatc gcgggctccc agcggtgcag gcaggagatg
     3721 acggcgtggc cgtaggcctg gccgacggcc atctccttct cccggccgcc gcccgccctg
     3781 gtcgcggccc ggaagtcctc gatcagcgcg gtggccagca gcgggttgcc gccgctgagc
     3841 gcgtggtgca ccggggccag cgtgcgcgcg gtgctggtgt ccaactcggc gcgcagcagg
     3901 tcttcgacac cgcgcttgga cagtggagcc aggcgcaggt gggtggtgtt gggctggcgg
     3961 gtgacctcgg cgcggaacac cgcgcgggtc ggacggggca gggcccactc ggtcagaatg
     4021 atcatgaccc gggcgaagcg catccgtcgt tgcaggtaga gcacggcttg cagggagggt
     4081 ccgtcggcga actggacgtc gtcgacgcag agtacgacca acgtgctttt ggccgcctcc
     4141 atgagggcgg cgcagaggcc ttccaggatc agcgcgcggg agcggccgat gctgacggga
     4201 tcgggccggg ccgcgtccgt gtcgccgctg agcaaagagg cgacgttcgc ggccacggcc
     4261 tcgggtaatg tctgcgcgct cgccaattgc ttcagcacgc cgaaggccag gctgtgctcg
     4321 gcccgtgagc ccgtcgcggt gagcaccgtg gcgcccttgc ccgcggcgtg ctcggcgaag
     4381 gtgtgcagta gttcggtctt gccgctggcg accccaccgc tgatcagcgc gacctgcccc
     4441 cggttgcgtg cacagtcggc gaagagccgg ttcagggttc tcagttcctc gttccgctcg
     4501 accagcgcca tccgtcgcct ttcccctgtg agcccaccgc ggccccggcg tcacctccac
     4561 acctgggccg aagtcactca tcgtgaccag tttttcccgt taccccacgg tcgagactga
     4621 atctaacggc atcgcgagca attgtggaag gtttcccaag tgcccaggtg agctttcctc
     4681 gatcttgacg gcgtctcact tttcctgtcc gccgttcggc ccattcgact catccctcgg
     4741 tcgtacaacg gccgcccggg tcggtgaagc gacaactact ttcccacatg ggggcacccg
     4801 gcgggctgaa cgacgaaggt gcacgccggg aagcgttgga gggttggcca gtttccaaca
     4861 gcgaacctca agaccagatc aagtcccctg tggacctggt tgggacaacc gtctccgggc
     4921 agacacctcg acggggttct tcggcaaccc gccacacagg acagacaggg ccgctccacc
     4981 atttcgctaa ctggcggtaa ccaatgtcgg atatccgcac gatctcggag cgagacgatt
     5041 catattgttt ccgtcaccgc cccaattggc aaagaatttt cgcggtccag tggcgggtcg
     5101 cgctttagcc gacgcacccg tgcgcgccta ccgtcacgga agtgactacg ttgacgacca
     5161 acggtgagga ggcgcgagat gtgggaaccg gacctgcccc ggttggtcag tctgctcgcc
     5221 gaccccgccc gccaccacga ggccgccgcc ctgctcgcca aggtcccgtg gatcttcggt
     5281 gcggcaggcc tgcgcaggtg gatcaaggcg gccatcgacc acggcgaacc gccgggcgcg
     5341 atcgccgcgc ggctgacaac gcacaaccga gccgtggtgc tgcgcgcgat ggctccgctg
     5401 gtggccgacg ggcactatcg gccgaccgcc gcgcgggccc tgcttctggc gttgggaggc
     5461 gcgaggtcgg ctccgccccc acctcgcgac ggcggatacg gccaggcacc ggtcgatccg
     5521 cgaccatact gggaacgccc gcggcccgac ccagagtggc ggcagtggcc gcccggcccc
     5581 tatcccggct ggcagaccgg cccaccgctg aaccccggca gacccctcac accatccgat
     5641 ccgggctatc cgatcgtgcc gcccttcgac cccgccgagc cggatcccga acagaccggc
     5701 gccttcccga tccccgaggg cccggagccg cccaccaccc gggaggcctg gcccgcgctg
     5761 gacttcccgg ccgcggtcgc cgccgacgag cgattcgaca tcgacgtcgg catcggcccg
     5821 cgccaggaca tcgaactatt cggcaccggg tcgttcaccg tgccctcgac ctcggtcgaa
     5881 ctagaggtcg tcctcatgta cgaccccgcc gcgttcgctc cggtcggctg ggccaacccg
     5941 atcaggctca cggtcacccc gacccgcccc tacccgctcg ccaccgtcgg catgaccgcc
     6001 ttgggcgggc cgaacctgcg cacccgccgc gatatcggcg cgtccttcta tgtcgacggc
     6061 ggcctgcgcg ggtacgcctc gcgcgggatc gaggtcaccg gcacgccctc cggcgtcgtc
     6121 ccgctgttcg acggcggcct gctcgacatc ggtccgttgc tggcccagga cgcgccggac
     6181 ctggtcgtcg tggtggagcg cggcgaggac ctgcgcgggc agaccctgtt gtggagcacc
     6241 aggaccaccc tgccgggggt gcccgccgcg ccaggtccgt tccgcagcga gatcggcgag
     6301 gacccggccg cgttcgcccg gcggatccga ctcgacatcg gtgcgttcgg cggcgacgcg
     6361 cgcggcacca ccctcaagct catcggcgtc ggccgcgcga tcgccgatca catccccgag
     6421 gaggtccgcg ccgcgctgac cgcggcggcg gccgcccgcg cccccgaacc ggccacggtc
     6481 ctgctgctca gctccgaacc gcacgtgccg tgggagctgg cggtgctcga cccgccgccg
     6541 cccggcagtc ccttcctcgg ctcggccatg gcgatcggcc gctgggtgct ggccaagagc
     6601 aggccccggc cgacaccgcc gacgcaggtc cgcgcggacc ggcacaccgt ggtcaccgcc
     6661 cggtacgaag gggtggcggg ctggtctcgc cttcccttcg ccgaggccga agccgagcga
     6721 ctgcgcctgg cctacccacc cgccgacgag atcgagccgc tgcactccgc cgtgctcgac
     6781 tgcctggaag ccgggccggt gggcggcgtg ctgcacttcg cgctgcacgg cagatacgat
     6841 ccggagaacg cccaggacgg tctggtcctg ctcgccccgt ccgacgccga cccgacccgg
     6901 ctggtgcccc gcttcctgca acccgaccag gtcgccgcgc tcgagttcac cacggcaccg
     6961 ttcgtgttcc tcaactcctg ccaggtcggc gcggcaggcg aggtgctcgg ggactactcc
     7021 ggcctggcga aggcgttcct ggcggcgggg gcggcaggcg tcgtcgctcc actgtggaat
     7081 gtcaacgacg aggccgcggg cgcgctggcc gacagcttct accgcgccgc ctacggcccc
     7141 gagtcgctgg cgcccgcgga gttcctgcgc cgggcccggt cccaggtgac ccgcaccgac
     7201 ttcccggcgt ggcccgcgac cacgctggca taccagttct tcggccaccc tcgcctgagg
     7261 ctgcgccgcg acaagggggc aaaccatggc tgaaccgctg cgtcccgacg ggaccgccgt
     7321 ccgcgtcggc gacatcgtcg tcgtctcacc gggcctgacc ggcagggtgg aggtgctgcc
     7381 gccgggcagc gaggggatga gggccgccga ggacgcgcgg gcggtgctgc tggctgcgtt
     7441 ggcgagggaa gggttctccg agcagctcac cgtccggctc atcgatccgg tcgaggtccc
     7501 ggaactggct tccgggacga gccgggcgac cagccttggc gaacctgcga tcacggtgga
     7561 ggttcccggg ccgggcgccg gtcttggtca gctcatcctc gcggccgatg aggacggggc
     7621 gctgagttgg cacctgcctg acgacatcga ccccgtcgac gtcccggacc ggggcggtga
     7681 ccgccgcacg tatacctttg tccgcgccgt cgcgccggtc gaccccggcg cttcgcgcgg
     7741 gttgatcggc gcggtggggt cgaagttgtt gaaggtactc gtgtttccgc tcatcgatcc
     7801 ggtgcttggc aaggtcggcg atcactttgt cagccgttgg gagcagcaca atcggccggt
     7861 tcggttgcga cagttcactg tgggcggtca tcgggagtcg tcggcggcgt cggttgattg
     7921 gtcctcgctg agcgcgggac ctgctctgtt gttcctgcat ggcactggaa gtcagagtca
     7981 taccgggttt catggggttt cggacgaggt tctgtctact ttgcacactc ggtatggtgg
     8041 tcgggtcttt gcctatgacc atcacacgat cgcgacggat cctgtggcca acgcgcgttc
     8101 gttggtcgcg cagattcctg ttgacgctgg gctacggctt gacattgttg cccattcgcg
     8161 cggcgggctt gtcgggcggg tgttgtgcga gttgccgggg gagatcgggc tgacgacgga
     8221 gcggatgagt gtacgcacgt tggtcatggt cgcgacgccg aacgctggca ctccgctgtg
     8281 cgatccggct catgtggcga agtggcttga tcggatgacg aatctgctgc agtgggtgcc
     8341 ggacaatgga atcactgaca tgttggacgt cgtactgacg gtggtcaagc aggtggcggt
     8401 gggggcgttc cgggggcttt cggggttgat gtccatggat cccaagggtt ctttccttga
     8461 gcggctcaat cagccttcgg ctcactcggt tgcttaccgt gctttggcgt cgaactatga
     8521 tccgccgaag gggtcatcgc tgttgcgcag cgcccggaac gtggcgacgg actcggtgtt
     8581 cggctcggcc cacaatgatc tcgttgttcc gactgatggt gtgttcgctg cgaacggtgc
     8641 tttcggtttc ccggtggggg aagtcgagct gttcgacgcc gaggtcggcg tggatcacag
     8701 tgggtactgg actcagccga ggttcgccgc cgctgtcgac cgctggctgg tcggctgaga
     8761 atcgatcagc gcggcatccg acgccagagc gggcggggca ggagtcgcag cagggcgaac
     8821 agggggcgca ggacgccggg tacccagacc tcttggcggc ccttggccaa cgcccggacg
     8881 gtggcctcgg cgacctggtc cggggtgctg gagaacggtg cgggggtcat gccgtcggtc
     8941 atcctgccga tgacgaaacc tggacggacc agcagcactc ggacacctga gcccgccagc
     9001 gcgtcggtga gcccgcaggt gaagccgtcg aggcccgctt tggccgaacc gtagacgtag
     9061 ttggccttgc gcacgcgcat gcccgcgacc gacgagtaca cgacgatcgt tccgcgtccc
     9121 tgctctcgca tcatcgcggc gaggtgggtc aggatggcca cctgcgcgac atagtcggtg
     9181 tggactacgg ccaccgcgtg cgcggcgtcg gtctcggcgc gtttttggtc gccgaggatt
     9241 ccgaaggcga tcaccgccgt gtcgattggt ccgtgttctg ccacgatccc gtcaaggacc
     9301 gggcggtggg tgtcgagggc gtcggcgtcg aactcgattt ggtcgacagt ggtcgcgcct
     9361 gcggcccgga ctgacgccgc ctcggctttg aggtcgttgc tgcggcgggc ggccaggacg
     9421 acggttcgcg ctccccgctc ggccagtcgc cgcgcgacgg cgacgccgat ctcgctgcgt
     9481 ccgccgagga tcaccacagg tcccattggg ccagtctgcc gggcggcgcg ggtgatcgac
     9541 acggcgggtt ccggacggcc cacgatgatc gagtgacgtg tcggaaaatg actactcgcc
     9601 gtcgccatta cgactggatc gagtggattt cgcgaggtta tcaccagccc atccggtgac
     9661 tgccgaacac catttcccgg tgataacttc acagggtcgg cagccagcgg acaacgcgaa
     9721 atctcgatga gagaacacag aggacgtcga gacgcgggtc gggactccgc gccatcggcc
     9781 gacgcttcca cacactagat gattgattcc tgactatcgc ctggtatcgg ctggtccacg
     9841 gcgtcgctgc caaggcgcag ggacagcgcg cgtaccgggt gtacgtggct gttcctgtaa
     9901 cgcgggcagc ggcgtcgtgg gccggtcgag acctggtgat agtcaggaat caatcatcta
     9961 ggcctatttc cccatgcccg cgaggagatc gaccaccacc atggcaccca ccgaggtgat
    10021 caccgggttc cgttcggcgc gtgcggtgct ctcccagagc cgctcgctgc tcgaccccgc
    10081 catccgcgcc gccgtcgact cgttgcccgc gacgatgcgg cgcatcgccg ggtatcactt
    10141 cggctggtgg gacgaacacg gcgggccggt gcacgccgac agcggcaagg cgatccgtcc
    10201 ggccctggtg ctcacctcag ccgaggcggt cggcggatcg ccgcgcgacg ccgtgcccgc
    10261 ggcggtggcg gtggagctgg tccacaactt caccctgctg cacgacgacg tcatggacgg
    10321 cgaccggacc cgcaggcacc gcccgaccgc gtggaccgtc ttcggtctcg gccccgcgat
    10381 tctcgcgggc gactccctgc tcacgctggc ctacgacgtg ctggccgcca ccgggcatcc
    10441 ccgcgcgcag gacgcctcca gggtcatgtc cgccgccgtg ttggcggtgc aggagggcca
    10501 ggccaccgac ctggccttcg agaagcgcgc cgacgtcacc ctcgccgagt gcgtgcggat
    10561 ggccgagggc aagaccggcg ccctgctcgg ctgcgccgcc gcggtcggcg cgctcttcgg
    10621 cggcggcggc gcaccccagg tcgaccacct ccgccgcttc ggcgaacgcg tgggcctggc
    10681 cttccaactg gtcgacgacc tgctcggcat ctggggcgat ccgaccgcca ccggcaaatc
    10741 ggtgtactcg gatctggaga gccgcaagaa gtccctgccg gtcgtggccg cgctcagctc
    10801 caacacgccc gcgagccgcg aactcgccac gatctaccac cgtcgcaccc ccctgtccgc
    10861 cgccgagttg gtccgcgccg ccgagctgat cgaacgggca ggcgcgcgca cctgggccca
    10921 ggcccatgcc gacggagtct tgaccgacgc ccttacccac ctcgaccaag ccgcgcccgc
    10981 cccgcgcgcc gccgccgagc tgaccgcgct ggcccacctg accgtccgcc gcgaccactg
    11041 atccacggag gccgtgacaa tgcccgatcc caccgcaccg gtcaccgtcg ccgatcacct
    11101 cgtcggcgac gacaccctgc cctgtcccgc cgccccgctc atcgagggaa cgctgcgcag
    11161 gcaaggcaaa tccacccgcc gcggcccgct gaccaccggt caggcgacgg cctgggtgtc
    11221 cctgtcccgc gacaccgcga tcgccgtcga cagccagacc gcgcacaacg ctctagccca
    11281 ctggatcgcc gtcagcggcc cgaggcgcat cctgctggcc gccccgcggg cgttctgcgc
    11341 gggcgtcgag cgggccatcg acatcgtcga ccgggcgctt gaagacggcc cggtgcacgt
    11401 ccgcaaacag atcgtccaca acgtccacgt ggtcaacgaa ctcagcgcgc gcggcgcgat
    11461 cttcgtcgac gaactcgacg cggtgcccga caacgccacc gtcgtcttct ccgcgcacgg
    11521 tgtcgcgccc tcagtgcgcg aggacgctgg caggcgcggc ctccaggtca tcgacgccac
    11581 gtgtccgctg gtcgccaaag tgcacgccga agccatccgg ttcgcccacc ggggcgacac
    11641 gatcctgttc atcggccacg cgggccacga ggagaccgaa ggcaccctcg gcgaggtccc
    11701 ggaccgcacc atcctcgtcc agtccgccgc cgaggccgcc acggtcaccg tccccgaccc
    11761 gagccgcgtc gcctacctca cccagaccac gctcgccgtg gacgagaccg ccgagatcat
    11821 cgacgtgctg cgcgcccggt tccccgactt gaagggcccc ggctcggacg acatctgcta
    11881 cgccaccacc aaccgccagg acgcgttgct ggccatcgcc gccgactcgg acctggtgct
    11941 ggtggtggga tcggccaact cgtccaactc acagcggctg gtcgaactcg cgaaccgcca
    12001 aggcacaccc gcccacctga tcgacgacgc cgcgggcatc cgctcggagt ggctggaaga
    12061 cgcccacacc atcggaatca ccgcgggtgc ctcggcaccg ccgaccctgg tcgacgaggt
    12121 cgtcgccgcg atcggcggcc tcggcaccat caccgtcacc gagtacgaaa ccgcgcgcga
    12181 aaccatccac ttcaccctgc ccggccaaat cagacgggac tgagcctgcc cgccacccca
    12241 agccgattga acgcgttgat caccgtcagc gtccacatca gacacgccag ctcggcctgg
    12301 tcgaactccg tcgacgcgac cgcgtagacc tcgtccggca cgtgcgactc cgacagcagc
    12361 gtcatcgact cggccagcgc cagcgccgcc cgctcgcgcg aggtgaagaa cggcgtgtcc
    12421 cgccagaccg tcaccgcgtg cagccgacgc ggcgtctcgc ccgcttccac cgcggccgta
    12481 gagtgcaggt cgacgcagaa cgcgcagccg ttgagctggg aggcacggat gcgcaccagt
    12541 tccagcagcc gccgctccaa acccgcgtcc accgcagcgc ggtccgcggc cgtgtgcagc
    12601 tccaacagct tgcgatacag ctccggcgcc gcggtcgtcg cctggacccg ggtcgcttcc
    12661 atcacgtcca tcgtccgctc ccaaaggtgt cgtggccgcg ccggatcagc gtgcgcagct
    12721 ccatccgtcg caccttgccg gtgccggtcc gcgggatctc gtcccaggtc agcacgatcg
    12781 ggtcggccag cgcgggcagg tcacgcagcg cgtgcgccca gccccgccga tcgagcgcgc
    12841 cgccgtcggt gaccagtacc ggcaccggca gctcacccgg cgtccccagg atcacgcact
    12901 cgaccacgga gggcagccgg tcctcgatca cgtcctccag ttcgacgcag ctctgcccgg
    12961 ggatgacgtc gacctcgcgg tccagcagca ggtaggcccc ggtccgggtg cgcacgccga
    13021 cgtcgccggt gttccaccac ccgccgacga ccttggcgtc ccaccgctcc tgctcaccca
    13081 cgtaccccag gcaccgcacc ttcgtccgcg ccaacaccaa acccggctga ccagcgggaa
    13141 caggccggaa cgtgcgcgga tcgaccaccc gcagccgcat ccgccccggc accggacggc
    13201 ccagattccg ggtcgagggg tgccgcgcgt cgcgttcggc gaccgagcgg cgggtgagga
    13261 aacggaacgt gagcggcccg gtctcggtct gcccccacac ctgcacccac agcggccgcc
    13321 gcgctgtcgc gccgaggaac gcgcgcacgg tcggcggatg catggcgtcg aaggtgctga
    13381 cgtagagccg gacatcgcgg aacgggttgt cggcacgctc ggccagcggc tgccagcgca
    13441 cgaagatcga cggcagcgcc tccagcgtgg tcggcggatg cgcccgcagt accggttcgg
    13501 ccccgtcggc gtcggcgatg accaccacct tgcgcggcgc gagccacagc acgctggccg
    13561 tccacgggat cgcccgaccg tggcagtagg ccagggccga gcacaccgtg tcggtgggtt
    13621 tggacgacac caccggcagg cgggccgcct cggtggcggc gaggccgtgg atgagcgtcc
    13681 gggtgctgtg catgaccagc ttgggcgtgc cggtggtccc cgaggtgtgg ttgacgacca
    13741 aggggtcatc ggggtcgcgc gagaccggtc gcggcggttc gtgcccgcgc agccgatcca
    13801 ggtcgagcgc gccggggtgc ggtccgtcga gggtgagcgt gcgccgggcg aagcccatca
    13861 ggtcggtctc gttgtcgcgg gcgtggtcga gcaccgcgtg ggtggtgacc agcagcgccg
    13921 ggtcgagccg cttgagcagc agttgcaggg tctcgggggt caggtggtcc gacagcagcg
    13981 cgggcaccgc gccgaccctc gccgccgcgc aggccagcag cacgtagtcc caatggttct
    14041 ctttgaccac cgcgacccgg tcgccgggcc gcaccccggc cgcgtgcagc caccccgccg
    14101 cgccgcgcac cagggcggcc agttccccga cgtcgtaggt ggtcccgtgg tcgggcgcga
    14161 tgtcgagcgg cctgctcagt tcgacgaccg tgctgacacc ccggtcgacc aggtcgtcga
    14221 acagcgtgcc cagatcggtg ggcttcatcc ggtgtccttc ctgccgacga cggtcaccat
    14281 cacctgcgac agccagcggt gccgcgtgtc catcaggtcg gccaccgccc ggtcgatgtc
    14341 cacttcagac actgtgccgc gggcaagcat cgcgggccgc aggtgcgcca gccagagcgc
    14401 gaaccaccgg cccccgtcgc tcccgccgcg cacgacctcg gcccgcccga cggcccgcac
    14461 gtcgaccaac ccggccgcct cgacgaggtc gacgtcgagc agaccgcagc gcgggtggta
    14521 gcccgcgtcc gccatcacgt catacgccgc gcgtttcacc tcggggtgga acggcccgtt
    14581 cgcgtgactg aacagcgaag tcgtgtccgt gtcctccagc accaggtggc cgcccggccg
    14641 cagggaccgg cacagcgcgg cgaccgcggc gggccggtcg ccgacgtgct gcatgaccag
    14701 cctgccgtgg acgaggtcga agtcgccggg cagcacgtcg gcgccgatgt cgagttcgcg
    14761 gacatcgacc ccgcgcagcc cgaccagccg cgacacgtcc aggtcgaccg ccgtgacctc
    14821 ggccccacgc ccggccaacc aggccgcgat cgacccgcga ccggcgccga cctccagaca
    14881 ccgccagccc ggccccacgt ccaggtcggc caaggtcgcc ttggttccct tgtcccacaa
    14941 ggactcaccg agccgcagcc gttcaccttc ccgctcgaag gacgtgccga agacgtagcg
    15001 gaccgcggtc tcagccaccg aacaccgcca acgcgctatc cgacccgacc aacagccgat
    15061 ccgcggtcat ctcggccgac cgaatcgcac cctcactgct cggccgcaac acgcaccagt
    15121 caccggcgta ctccacagtg gacaccggcc ggtgcagaaa gtcccggtat tcgtccaaag
    15181 ccgccgctgt cggcatcggc agaccatgcc gatagcggac caccaccgac acccggcacg
    15241 ccgaggccaa ctccggcagg tagcgggcgg cgtgcgacat cagcaggtcg gagacctcct
    15301 cgttcggggc gtcgatcagg ccatcggcga cggccgctcc cgcgaacaag gtcaccagtc
    15361 ctcgacccgc gggcgcccga cctggcttgc ggtggtcgat gaggaggccc gcgaacgccg
    15421 ggttctccac cgacggcacc gcgatccccc acgcgggact tccgccgatc ggctcgatcg
    15481 ggcggtccag caggcagatc accttgacca tcggccggaa ctggcacgcg cgcacgaagt
    15541 cgggcgcgtc cgcgtgcagt tccgccgcca ccggggcggg cacgcacagc acgaccgtgc
    15601 gcgcgctcag cggcgctccg tcgactacca gcgtcgcgtc ccgttcgccc gcgacgacct
    15661 cgtggacggt gacgccggtg ctcacgtcga cccgtgcggc gatctgccgg gcgagggtgt
    15721 ccatgccgtg ccgccaggtg cggaacgtgc gggtggggcc gaccgcgagc aggtggctca
    15781 tcagcggtcc ggccgccgcc cgttcggtgt cccagccgaa gaagccgccc gccatcggct
    15841 gcagcagata gtcgtgcacg tcggggtggt agcggcgcgc gagttcgcgg acggtggtcg
    15901 agccgagcgg ggtgcggtcg ggccggtcga cgtcgtagga gcgcttgcgc aggccggagc
    15961 ccaccatcag cttggccagg ctcgcgcgac cgctcaccga catccccgcg cccttgatga
    16021 gcccgccgag atcgccgacg ccggggtggg ccacgccttc gcgccacatc gccaggggtg
    16081 tgccgagcag cggcgcgtcg gcctggctca ggcccagttc cccggccagc cgccaggtcg
    16141 cgtcgtagcc atgggtgccg accatctcgg cgcccgtgtc gatgacgtag ccctcgcgcc
    16201 gcaccgtgcg catccggccg ccgacgtggg ggctggactc gaacacgtgc accgaccggc
    16261 ccgccgcgcg cagccggtgg gcgagggcga ggccggagat gcccgcgccg acgatcgcga
    16321 cgtccaggtc cgcgctcaca gccaccctcc cagcacgttg atggcgaaca ggagcacgaa
    16381 ggtcagccgg tgcgcccgca gcccgagcgt gcgggcggcg agcaggtcgc cgatgccgac
    16441 cccgcgccgc agctgcgcga tccgaagcag gacggcgggc atcatcgcca gcgcgaacca
    16501 ccacggggcc gcgccgagcc cggcggaaac cacgatgact gcgatctcgg ccaccgacag
    16561 cgcggcgatg aacagccggt tcccggtcgc cgagagcaga accgccgccg tgggccgccc
    16621 gaccgcggcg tcgccgtcgg cgtcgcgggt gttggagtag acgccgaaca gcagcgggcc
    16681 gagcccgaag agcacggcct gcacgatgcc gaacccggtg atcgcgccct gcgcgaaccc
    16741 gaccgcgcac agcaccagtc cggtgccgaa cccggccagg aacacctctt gccacccgcg
    16801 gtagctgatc ttgagtcccc acgagtactg cacggccgtg accaggcaca acacggccaa
    16861 cccgactgtc cacaagagag cgaacggggc cgccgcgacg cagacccccc agcacaccgc
    16921 gccgatcccg gcggtggccc agccgaaccg aacagcgtcg acgacagtca gttcgccggt
    16981 cagcaggggt ttgcgggcca gtttgcgggc tgacgcgttc ggcccgtagt tggcgccgtc
    17041 gctgccgtcg acgaagccgg tgacgtcgtc gaaggccacc gcggaggcga ccacgaacac
    17101 cgtgcccacg ccgaacagcg ccagcgtcgc gagcacgcgc gggtcgaacc acagcgccgg
    17161 gccgagcagc gaccacgcca gcggcagcgc gaggtagtag tcccacacgt ccagcttcgc
    17221 cagccgggcg taggcgccga cccgtccggg cgcggcggtg aggatggcgg tcatcgcgag
    17281 cctcccggga aggcgcagac cgcgtcggcg atcgactcga cctgggcgtc ggtcaggtgc
    17341 gggtagatcg gcagcgcgag gatgcgcgcg ctcgcgagct ccgcgtgcgg ccagaaccgg
    17401 tcgcgcgcgg cgtactcggc gaacgcgggc tgggcgggca gcggggtcgg gtagtagacg
    17461 tgcgtgccga tgcccaactc ggccaggtgg cgcttgaggt ggtcgcggcg gtcggccagc
    17521 agggaatata cgtagtagca acggccttca cgccccggtg gcggcggctg gatcccgcgc
    17581 tcggccaggg gtgtgaagcg ctcggtgtag tagtcggcga tctgggctcg gcgttccagg
    17641 cgggcgtcga gtcccgccag ccggtgcagc tggaactcgg ccatgatctc gtcgaagcgg
    17701 ctgttgaacc cgacgacgtg gtgaacgaag cgctgcttgc cgtcctggcc gtggttgcgc
    17761 agcatgcgga cccgcgcggc gatctccggg tcgtcggtga ccaccgcgcc gccctcgccg
    17821 atcgagccga acgtcttgac ctgcacgaac gagaagacgc ccgcctcacc ccagcggcca
    17881 gccggggtcc cgtcgagcac cgcgccctgg gccaccgcgg agtcctcgat cagccggacc
    17941 tcgtgccggt cggccagcgc gcgcatggtc ggcatgtcgg ccatcaccga gaacatgtgc
    18001 gcgggcatga tcgccgcggt ccggctggtg atcgactcct cgacctcgta gggctcgacc
    18061 accatcgtcc acgggtgcac gtcggcgaag accggtgtgg cgcccacgtt gaccaccgac
    18121 gcggcgagcg gggcgcagcc gaacgcgggg acgaccacct cgtcgccggg cccgatgtcc
    18181 atcgcgcgca ggatcagcat cagcgcggtc gtgccgctgc cgcaggccac gacgtcagcc
    18241 gcgccgagct ggtcgcgcag cgcggactcg aagcgggcgg tgctcgcgcc gaggatgaac
    18301 ttctgctcct cggcaaggcc gacgcggcgg acggtgtcga gcagcagctc gcggtcgtcg
    18361 tcgaacaggt ctgggggaaa gaagggcagc gagggaacgg tcatcggaag aaccccttga
    18421 tcaactcgca cacccggtcg acctggctct cggtgaggtc cgggtagagc ggcagggcga
    18481 cggcgtgcgc gcaggcggcc tcggcgttgg ggaactcgcc cgcgcggtgg cccagctcgg
    18541 cgaagcacgg ctggcggtgc agggggaccg ggtagtacgt ctcggtggtg acgccgttgg
    18601 ccgccaggtg ggcgaccagg tcgtcgcggc gctcgacctc gatcaggtac acgtagaaca
    18661 cggcggtggt gtcggcttga cgcttcacca ccgtgggcag gcgcagcacg cccgggcggt
    18721 ccgcgagccg ctcggtgtag gccgcggcga ggacggcgcg gcgggcgatg tcggcgtcga
    18781 gggtggcgag cttggccagc agcacggcgg cctggagatc gtccatcttg ctgttgagcc
    18841 cgggcaggac tgtttcattg ctgatgcccg ggaagtggtc gagcgtgcgt ccgaagcggc
    18901 cgtggtggcg cagtgccgcc gcgacctcgc cgacccgcgg gtcgttggtg atcaccgcgc
    18961 ccgcgtcgcc gagcgcgccg agggtcttgg tggggaagaa cgacagcacg ccgcccgcgc
    19021 cgtgcaggcc cgcgtgggtg ccgccccagc gcatcccgat ggcctcggcg ctgtcctcca
    19081 ccacggtcag cgcgtaccgc tgcgccacct ccgtgatccc ggacaggtcg gcgagctggc
    19141 agaacaggtg caccggcatg atcatccgag tgcgttcggt gatcacctcc ggcacggcgt
    19201 cggggtccat cgcgtaggtg accgggtcga tgtcgacgaa caccggccgc ccctgggcca
    19261 gcgcgaccga cgacgccgag gccacgaagc tgaacgccgg gaccacgacc tcctcacccg
    19321 gccgcaaccc ggccgcgcgc agcagcagga ccagcgcgtc ggtgccggag ttgaccccga
    19381 tcacgtgcgc ggcgccggtg tactcggcca gcgccgactc gaactcggcc acgagcgggc
    19441 cgtgggagta cttgccgccc tcgaccatcg cgttgaggtt ggcctcgatc ttgggccaca
    19501 cggcggcgaa gctcgcggcc tgggtgaaga acggcaccga aggggcggac gccgccgaac
    19561 ccgcgccggg acccgtcagt gtcgcggcgt gctccatgcg tgtcctttcc ggacggatgg
    19621 ttgagtggtg aagttcctgg acgcgcccga ggcagcgctt tccaacctag tcagagcaca
    19681 tccgttgaac cgcaacggaa tccaaagatc acacggtcgg gtggagaccc ccggtccacg
    19741 ttgacacctg tcccccgcac ctccagtgtt ggcgggcgtc acccgatccc gcgcaggagg
    19801 cagcaccgat gctcggctcg ctcgtcgtcg gactcggccg ggcgggaacg gcgctgcacc
    19861 tgccggtcct gcgcaggctg cgcccccacc agcccgtggt cgcctttgat ccacatcgga
    19921 ccctcgacct gccaggggtc accgcgaccg actcgctcac ccacgcggca tcgatcaccg
    19981 acccggcctc gaccgtggtg cacctgtgca cgccgcccgc ggcccgcgtc gccccgctca
    20041 ccgagctggc cgagctgggc ttccgccgga tcctggtgga gaagccgctg gcggcgaaca
    20101 gcgtcgagtt ggccgagatc ctgcgcctgc gcgacgccgc gggcctggac ctgctgccgg
    20161 tcggccagtg gcgctccagc gagctgaccc gccgcctgcg cgccaccctg gcggccggga
    20221 acctgggccg ggcccggtcg atcacgatcg tgcagaccaa gccccgcttc ggccgcgcgg
    20281 gtgacgacca cccaaccgcg ttcgacgtcg agctgccgca ctcggtgctg ttggccctgc
    20341 tgctcgccgg accggccaag gtcaccgccg cgacctgctc ggacatgctg ctcggcgaca
    20401 ccgtccaccc cgcgatgggc ggcgcgaccg tccaactgcg ccacgacagc gggatcgtca
    20461 ccgagatccg caccgacctg acctctccgg tgcgcgagcg gcgcgtcacc gtcgacctcg
    20521 acggcggcac gctggtcggg cacttcgcgg tcagcgacgc cgacgaccac gcccagctgc
    20581 gggtcaacac ccagggccag cagctgcgct cggtcttcgc cgacgactcc ctcggcgcgt
    20641 tcctcaggct cgcgtactcg cacttcgcgg gcgaggagcg gatcgccgac gagcccgaga
    20701 ccggcgtcgc cgtggtcgag ttgatcaccg cggccaagcg ccgggccggg ctggccgtcg
    20761 cggccggggt gcccgcgtga ggccgctgct cgcgggcatc ggggacgagg ccggtcccgc
    20821 gctggccgac cagctcgccg ccgtcgccga actcggctgg accgcgatcg agctgcgcac
    20881 ggtcgacggc gtccacatcg ccgacctgga ccgccgcgcc ttcgagcggg ccgccgacac
    20941 catcgccgag cacggcgtgc gcacggtctg cgtcgactcc cgcatcggcg actggtcctc
    21001 ggcgatcacc ggcgacttcg agcgcgatct ggacgagctg c
//
