LOCUS       NZ_LN850107            40602 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Alloactinosynnema sp. L-07 isolate Alloactinosynnema sp. L-07
            chromosome I.
ACCESSION   NZ_LN850107
VERSION     NZ_LN850107.1
KEYWORDS    RefSeq.
SOURCE      Alloactinosynnema sp. L-07
  ORGANISM  Alloactinosynnema sp. L-07
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2015) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900070365.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:00:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,999
            CDSs (total)                      :: 6,934
            Genes (coding)                    :: 6,831
            CDSs (with protein)               :: 6,831
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 30 of 103
            Pseudo Genes (incomplete)         :: 83 of 103
            Pseudo Genes (internal stop)      :: 1 of 103
            Pseudo Genes (multiple problems)  :: 11 of 103
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:22:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4368508
            Orig. end                         :: 4409110
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN850107.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..40602
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /product="lanthipeptide-class-i"
                     /region_number="24"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..40602
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="chemical_hybrid"
                     /product="ranthipeptide"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..38557
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:28557]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..28557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    138..153
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    537..552
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.35"
                     /tool="antismash"
     gene            complement(931..1869)
                     /locus_tag="BN1701_RS19650"
     CDS             complement(931..1869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657268.1"
                     /locus_tag="BN1701_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="WP_231949651.1"
                     /transl_table=11
                     /translation="MERDTQSTAHGKVGPPRLMGLALAAANDGHFVIPLRPRSKIPALH
                     GEAGCPRTGSCVDGHLGWEERATREPERIRAWWARAPMNIGIATGPSGLHVLDLDDAHG
                     QATPDLWTGTAHGRDVLARLAEEAGESYPGDTLAIGTPSAGEHLYFRAPAEPELRNTVA
                     RLGWRIDTRGAGGYIVAAGSITAAGRYRVVRDLPIAPLPQWLVPLMKSPVIPTSAVRTQ
                     PVTEQSRQAYLNTVLDTVARAEHGRRHHVLVRAAYTLGRLVAGGEYTYAAVHHGLRDAA
                     AQLTDFPTPEAERTIADGLRNGAKSPRRFDA"
     gene            complement(1910..2875)
                     /locus_tag="BN1701_RS19655"
     CDS             complement(1910..2875)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025200.4"
                     /locus_tag="BN1701_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4192 domain-containing protein"
                     /protein_id="WP_054050963.1"
                     /transl_table=11
                     /translation="MPDSSDDTAQFTTPTIPLGELIAAMTTFLGYPPVDSLLVYVVDGP
                     CIRVDLPAPEHCESLAAQMASVAAQHGHDMFVMVIGGQPDRDLPHRGLVESLTRRLKDL
                     RVTIHEAVWSPDVRAGARWVSYTTDHRGVVPDPDTTLVAVHAAYEGIPKFSSRADMAAS
                     LAPDPAEALRRRAELITQLRDQPDIATEAGHDLIKGVIAATNDGTDLDDDTLARVARAL
                     DDPDVRGWCLVSDDIPRDRSTNDAWARLVRALPAPERSFPACLLAIGTYLAGEGALTQI
                     AQEIAVTSDPDDTLAPLLGAAFQYGISPREMRAILRRART"
     gene            complement(2925..3950)
                     /locus_tag="BN1701_RS19660"
     CDS             complement(2925..3950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155732.1"
                     /locus_tag="BN1701_RS19660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF932 domain-containing protein"
                     /protein_id="WP_054050965.1"
                     /transl_table=11
                     /translation="MSTETATWLNRNVLIGFTEARGRAWHYRASAQGAEPNHYPGPIPI
                     ADIQRRLFNWDAIPGRVLIHTAEHGLCAAPTRKAVVASDTGDDLGIHTDRYAIHQYQEW
                     LLEKVDAVLDGGLRAGSAGLLKNRAQAWVSVEVPDSVRTPEGVVFRPHLIACTSHDGSL
                     STTYKRSITNVVCDNTLGAALRGAGQVIKVKHSKNAKFEVLTARQALDMVQVLADDYAT
                     QIAELCRVEVNDTAWREFVRAHAPDKSDSKRSRTLVATHRAELRRLWDHDERVSPWRGT
                     AWGVLQAVNTFEHHYRTVRGVSRAERNLTRTVTNWAETLDSGTLATLDAVLASTPVLAA
                     I"
     gene            complement(4039..4569)
                     /locus_tag="BN1701_RS19665"
     CDS             complement(4039..4569)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050967.1"
                     /transl_table=11
                     /translation="MHHTVHPQSAQPVDPPFALTISHEQGLIAILGPDPLVTITELLGG
                     TAPSTVDTELGILEFWVGAVADSQAPINGPAMILIEELIEAALTGDLAVSDAAQSRIKT
                     LRAHGWAPQIRGHCVVTGPLGDDGVPAPLPERFFRWLEARVHAAQNAHIERVLAELTEA
                     GLHVHLITITENN"
     misc_feature    complement(5193..5208)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.31"
                     /tool="antismash"
     gene            5197..7587
                     /locus_tag="BN1701_RS19670"
     CDS             5197..7587
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="BN1701_RS19670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_054050969.1"
                     /transl_table=11
                     /translation="MISDDGPLSTVHPGSPGDLTTFVGRADLLAEATELLLGPGRRLVT
                     LVGTGGVGKTRLARELAARVVDTFAHGAVLVDLTDVRAADDRVDAAVIEAVGLLDNATS
                     PARARLIEHLRDRSVLLVLDNCEQLVSLDGEGELPRLVSTLLATAPGVRILATSRVALG
                     VSGERRVRIPPMWVSAGGDPDGAVTEALALLLDRADAYDVTIAQSDYPLANELCRMLDG
                     LPLAIELAAGRLDVLTLDEIVDRCEDSMRLLVRSGRAEQRHHQTLHATLRWSFDLLLES
                     DQRMWVMMSVFDGGFDLAAAEGVCAAHGVDSGEVLDLLTRLVHASLLTTQARRGRTYYR
                     MLEVVRRFGHEIADPDELNRIRDSHAAYYGRLVDRAAREWYGPDESEWIDRLRRNLHNI
                     RAAVDHLVGQGDWMAALSIACDVTRTRTHICVGQINEARRLLRAGLNAHPEEPSELEVT
                     AVSMLAYLAMLQGSREEADPLLDRAERVATAIGAHASPALLFARGMRDWLVGQSNEEAA
                     KALTTLTAAIDTLGDTEPSERMAMLIVLAIAASVDGTEPAARETAEAFWAEVAESGVDS
                     VVSWALFAKSIVALRFGTLAQALDLVQRCLRLQYPSEDTWGPAWCLWLRAVIAARMADH
                     VVSARLFGAAHARHRATDVSMSGLKPWWRLQVDAERNVRRALGEDYDVEVAVGAALPYD
                     EAMVLALAVPTENGDGAGAGAHGLTQRQLQIARLVADGLTNKEIAAKLTLSTRTVENHV
                     LRTIGRLGLDGKGKPGLAAWYAENIHAGSPAATPTGSLAPRSG"
     gene            7696..8127
                     /locus_tag="BN1701_RS19675"
     CDS             7696..8127
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050971.1"
                     /transl_table=11
                     /translation="MGAVRALPSAASVRLTDTVAAFLDTITVANTRGYVIGLDRMVRDF
                     GADLNVRLLDPARAETAPDPAEVDMPEDPHEAELRHNAARLLTGAWVAGQLTAIPPRAW
                     PEDFPRHRLAVAARAQIQGEIDENLDQPGECQGAEGGSR"
     gene            8124..8891
                     /locus_tag="BN1701_RS19680"
     CDS             8124..8891
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020500991.1"
                     /locus_tag="BN1701_RS19680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_054055979.1"
                     /transl_table=11
                     /translation="MSRARTRSGGFVEQVRLDPHADTGSYPFTLPIVRHLDRVGGLELD
                     PGVTFLVGDNGTGKSTLVEAIAVAAGFNPEGGSQSFRFATRATESSLGDHLILRWGTRK
                     PRTGFFLRAESYYNVASEIERLDREPGPSLLPAYGGVSPHERSHGESFLDLVTHRFGPN
                     GLYLLDEPEAALSVKGCLALVARMAELIGQGCQFVVATHSPILLAVPRARILQVDGDGE
                     IEQVAFDEADPVTLTRGFLDSPQRFLRHLLADE"
     gene            complement(9120..9974)
                     /locus_tag="BN1701_RS19685"
     CDS             complement(9120..9974)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="WP_067520790.1"
                     /transl_table=11
                     /translation="MTGENELSAADAAHRAWLADVYAKAAATADATLDGALVFGWRDRS
                     AGARVATAAGPRWLRLVIEQHGWAGGAFWTGNADANDVTGVAKPWVLRHWDLTDGDWAV
                     RAELMTLMPGARCSPTPELREPLAVAPAWWEALWSSLAAVAATATTRIALGQDDLSRRV
                     EMFFGDRAGDTTVNTWTAAHGDLHWANLLQPECALLDWEGWGTAPAGYDAACLYVHTLL
                     VPAAAAAVRAELGLLLDTRDGLLAQLYATTRMLMRVDQGDYPGMAIPLHRNAEQVLARL
                     TSA"
     gene            complement(10001..10924)
                     /locus_tag="BN1701_RS19690"
     CDS             complement(10001..10924)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783522.1"
                     /locus_tag="BN1701_RS19690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_157368088.1"
                     /sec_met_domain="PF04055 (E-value: 5.3e-15, bitscore: 54.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.5e-09, bitscore: 34.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARISFLWLELTGFCQLECDHCYAGSGPSGTHGSMTRADWLRVID
                     QAAAAGVGMVQFIGGEPTLHPDLRELIAHALAAGLEVEVFTNLVHVTAPLWEMFTRPGV
                     SLATSYYSDDPDQHAQVTRRPSHARTRANIAAALRRGIPLRAGVIDMGGDQRATQAQTE
                     LVDLGVPAVGYDRLRQVGRGVRDQAPSTDQLCGNCGDGVAAISPDGAVWPCVFSRWLPV
                     GNVLEHELTEILDSPAADAVRAELAAAFAGRAPSACKPDCAPKNQPCNPDCTPSCNPHC
                     QPTCSPRCSPTCDPVRCKPNSCWPRY"
     gene            complement(11054..11191)
                     /locus_tag="BN1701_RS35720"
     CDS             complement(11054..11191)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS35720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157368089.1"
                     /transl_table=11
                     /translation="MRSTSLTDELAAPSRCGEPSMVAGSVTRTLLGGLMLDFVLIPALS
                     "
     gene            complement(11226..12494)
                     /locus_tag="BN1701_RS19695"
     CDS             complement(11226..12494)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BN1701_RS19695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_054050973.1"
                     /sec_met_domain="p450 (E-value: 8.6e-13, bitscore: 46.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPRSGGELFADGFWDRPLDEVDSLRAQSKVYRSTLTSGVRVWVI
                     TGYADAKRALTDPRLRKDARTIHAIIDGQQTRLGDMAQVAGILDTHMLFVDGLDHARLR
                     RIVGLEFTRARVEALRPRIEVLAASMLDALPVDEPVDLVSSLACPLMLAVICDLLGIPS
                     GDRELLSEWTTALMEEDVPRTVRATWALSSYLNTLIDHKRSEPGDDLLSVLIHPRDAGD
                     CLSTEELLGTVFLLLTGFQASANLITTAVFRLLSHQGSWNRLRESPWLLPTAVEEILRF
                     DTPMRMTTHRYTTEPVEYGGQPIPAGEIVLVWLHAANRDPDLVRCPDAATLNLERSPNS
                     HLSFGHGAHYCFGAPLSRVAATVALGSMTRRYPKVRLLDVVARHAPSATMNGLLALPLV
                     LGPVDLGQPRHGDLRRHTIEHTD"
     misc_feature    complement(12816..12830)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    complement(12931..12943)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(12961..12976)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    13230..13244
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            13470..14879
                     /locus_tag="BN1701_RS19700"
     CDS             13470..14879
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="BN1701_RS19700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diguanylate cyclase"
                     /protein_id="WP_054050975.1"
                     /transl_table=11
                     /translation="MFGRAGVSVSRSGFVVKGRTRDKNQEQSDSLWDLGGATIAVVLLI
                     DLIGALAVTARAIGAAPPRLADWLLFLALLTAAIVYVWLTRPVEERRRGARLAQRTVEH
                     VDQTSIFFAAAGLTLPTLLAVALVVVIRYRRFLVARKPIGLWTSNTFTVLLSVVGVGWV
                     RDLIGGATWLSGSFVADLSTGVRSGVVLGAAIAVYFLAQAVPIGLYRGVRFGAWTLGAT
                     LGAREDNLLIVHTLVLGMFAALVTAHAPILLPVIVALAVRDSRMVGRLATTTADALTDP
                     LTSLPNRRAFDLHATVALEIDRAGRQPTSLLMLDLDHFKAWNTTLGHLGADQVLVAVAD
                     ILRKVKRKGDLIARWGGEELAMVLPNTDPHGAEQIAERIRVAVEDLRLAIRKPAGGVVV
                     CLGTGGVPNCTISIGAATSPHHAVDLPALQECADQALELAKQLGRNRVVSFQPRGSERV
                     LPAVETQESTN"
     gene            complement(15250..18516)
                     /locus_tag="BN1701_RS34430"
     CDS             complement(15250..18516)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BN1701_RS34430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_082859936.1"
                     /transl_table=11
                     /translation="MFLDRWRRTESPSDDLDVLITEYEAGREDNRHTLTQHTTIILAAV
                     TALGGILLLSDNVKMDDGIRVLLCGIALAISTYAAVYFASATARQLYMRAVEERIANLA
                     NTDLGGSLHGENDGPAPVIRLPAIGSIERAINSPRQRNRITVAHWFIYAVVLTVPAAVV
                     LKLTLEIDNHYIERGILLFEMVYCPFISWVIWSTSSSPTRFFAKVLRWTEERGGAGAGA
                     TPRRALIRYLVWPRPADAIKATYYLVACGVGAAIYDPSTEALINALIFWVALEPLAYQA
                     RYAWNDLRDADHDQAHTQAKARGRIPWNKDDPEDPALRLVAIMVVARLGIAFAVVTLLV
                     KGGSAVGWGLVFLLALLVHTFVYEAARVVTKRGTRAGRAAQALKKPKIPEHVVYLLVGL
                     GYGLRATAGLWFGSGATERSPEVLASFFGFSTMLGIANVTMVWLFEGSTLATPAAVGKG
                     SQKSHVTSLWNHYRYRSKLPAIAAEPNRERWLLDRDLIRSPWFIAHIAAGCAAVVLGGV
                     LWHEIAKRGRIGSLPDHGEWFVAAGAVIWCLTGIVLARLPVNDGWLVGLGIPVVAVVAL
                     APRLGPGVIIALAPIVLVIVVYLATRSGNYDTAVSGLGNLIARSRKMVRSIGLGILSWL
                     LPGSVASAVVSERVSERLAEREEAERQLLESGRVPTKWLVQFALAGYGIWLAFSTPIAL
                     LLPGRLQAMLPDAWSVEHGWILAAGAMVAVIVNIMAGYWSDRTTGEFGRRRPFILVGSI
                     GGSLAVAGIGFTANWWQILIAWCVAQAFLNAMLAGLLALMVDKLTRRQLAGAVTMFGAA
                     QIIGPMLGGVVTLSLRPDSPFPWIIVGITAVVLTIPILIGADETPMSTAAPGRRPRLVA
                     IFREHIFGNRNMGMAFTARLSFQAAFTVGVAYLPFYLLKTVGQKVGSFPSMVLSMAVTS
                     FFVGAAALSFGPRAEKLPGSEVVILKRYVTRSGIVMAAGLMCLIAIAFVDSPSLRWVLI
                     VGVAAVLGVGSGLFAPTDLHLNTKVLPDRNHHGAYLGVFNTASALPQVLVLVVALNAAS
                     TSGGHVAVFVIAAAFALISAVFVQFVRVDVTTTSTDDEVH"
     protocluster    15588..40602
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[25587:30602](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      25588..30602
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
     misc_feature    complement(15703..15705)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15745..15747)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16141..16143)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16147..16149)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16480..16482)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16924..16926)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17695..17697)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    18537..18547
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(18620..19444)
                     /locus_tag="BN1701_RS35725"
     CDS             complement(18620..19444)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS35725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157368090.1"
                     /transl_table=11
                     /translation="MTDTSDGRRQIDSPEAFRADLAEALRRGNLSLRQAEKKSGWAKST
                     IARAIKDGIPKLDLVIDVLTAAGVQAPELEEWRARHDRLVLLPPTPPVLDTAAPTDGPP
                     PPRQRPPVRRRWLVLAGVGILVITAALSVMVTFFVTEPTQDQSSTAVSPPSSRPVAIVV
                     QNKVAIGTELLEDFTPAYLSSKPIPFCGRDGCKLEDTDMSSGAALVVDCFVFGATMSNA
                     DLSSEGIDRNPHKHSSSRWYRALLPGDRSGYLAEVYVAPEYRGGLGLAECRG"
     misc_feature    complement(19370..19372)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19400..19414
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(19613..19627)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.6"
                     /tool="antismash"
     gene            19735..20124
                     /locus_tag="BN1701_RS19710"
     CDS             19735..20124
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050979.1"
                     /transl_table=11
                     /translation="MFKRALRIFALAIAALAALLLPGTVATASNSGADTVAACRYATYA
                     PARSGSNVTGWGEKWECGGSTSWTITLQRHRGGGWWQNEARNYATGDGWVSVTAGCVPG
                     TWTYRTILESNVGHKTVSSHAAISC"
     gene            complement(20181..20345)
                     /locus_tag="BN1701_RS37405"
     CDS             complement(20181..20345)
                     /EC_number="3.5.1.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012913.4"
                     /locus_tag="BN1701_RS37405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparaginase domain-containing protein"
                     /protein_id="WP_197672233.1"
                     /transl_table=11
                     /translation="MADTGIVVEVEDFRRKPGASLTFDDLHALADTVRIRCGEGIDGVV
                     AKQGTDTIE"
     gene            complement(20676..20936)
                     /locus_tag="BN1701_RS19715"
     CDS             complement(20676..20936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015786779.1"
                     /locus_tag="BN1701_RS19715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_054050981.1"
                     /transl_table=11
                     /translation="MIYESWAGASFRKSSFSGGESGSCVELAWRKSSFSGGASGSCVEI
                     AQADDLFGIRDSKNISGPVLELTGARGRALIAAVRDGRITE"
     gene            complement(20933..21820)
                     /locus_tag="BN1701_RS19720"
     CDS             complement(20933..21820)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="BN1701_RS19720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_054050984.1"
                     /transl_table=11
                     /translation="MNESGLPRALQSGSPALFRRMINLSLKRWRDEAGLKQAESATRIG
                     RSIAHISNIENDRLPPASDLELLLDLYGKGDRIPFMRELLAAARNANRWWASLSGNVPK
                     WFDLFLGLEFGATELASFDCRTVPGMLQTPAYAHAVISGNPNLSEAEVAQLVEVRVGRQ
                     QILDRDNEPARLVAVVDESVLYRKRGDGHVMIEQMKHLIEASRRPQIELLVLPFDAAPN
                     PAQDGGSFYLLDFPTETDDPGLVYVELVTGGEYVEDARDIEQYRHALDTLRDLAADQKS
                     SRAIIQRALKEVKL"
     gene            22378..22839
                     /locus_tag="BN1701_RS19725"
     CDS             22378..22839
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157368091.1"
                     /transl_table=11
                     /translation="MNSLLTIPWRMPTGNDLATTVSAYRKLGWDTFPDEHGSIMAGVGE
                     RFDVATFPDALAPAFLSELPDAPVFVDARIHRCTVLTSVACDQVRDVAPDLAEARVRAL
                     PRRTPVMLPVLMEDDWDGHRRWLVAPDAAVLPGWDETIAAIGRAIEVAR"
     gene            22836..23330
                     /locus_tag="BN1701_RS19730"
     CDS             22836..23330
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050988.1"
                     /transl_table=11
                     /translation="MTAATAPRMPLYEQGLLRALRMVDRGRIGAFGLTAPLGFHSGDVP
                     PSWLISALFVLRRDELAALGPAESGDGWRPAVLTSLGTALLAAWNKRLSDAKPYVLAVG
                     TVTPVLHVVATEDHLPRVADTDDGPRWIALCRGLTRPERADRTVGVVLCERCALEARGA
                     A"
     gene            23375..23590
                     /locus_tag="BN1701_RS36500"
     CDS             23375..23590
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS36500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050990.1"
                     /transl_table=11
                     /translation="MDYPAETACWWGSSPHYRGRAHLIVGGARSALCGILVDESTGYRP
                     FGRTCPECALAYVDRFFVPTTRGWPS"
     gene            23587..24075
                     /locus_tag="BN1701_RS35735"
     CDS             23587..24075
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="BN1701_RS35735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_067520793.1"
                     /transl_table=11
                     /translation="MRGRSPAAGDPRAAQLGAELRSARLARGWTRSEMAALLPFDVTFQ
                     TLASYELGNRHCTVMRLLDLCDSLEVSASEVVGVVSCHAGDCPAPTGIVVSCAVLARTT
                     RPALHPLRRWAKTMVTRDPSRDRVVLSDAAVVIAAELCGLSPATMDAHLRTCLKYSTR"
     gene            24090..25331
                     /gene="fxlM"
                     /locus_tag="BN1701_RS19745"
     CDS             24090..25331
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698391.1"
                     /locus_tag="BN1701_RS19745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_231949653.1"
                     /sec_met_domain="PCMT (E-value: 3e-45, bitscore: 153.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVQDQTDTSVSDPDLLRAAMVAEMRREGDIRTDEVAAAFAAVP
                     RHLFAPSASVDEAYRRDDIVERKYDENGLVTSSVSAPWLQAMMLEQAELKPGMRVLEIG
                     SGGYNAALIAELVGKSGQVTSVDIDTEVVARARRCLDATGYERVEVVLGDAEHGVAGRA
                     PFDRIIVTAGAWDIPPAWVDQLADDGRLVVPLRMRGLTRSVVFARDADRLVSTGYLLCG
                     FVAMQGEGASAERLILLRGEDVALRVDGDHDFDVAGLRESLSAPRAERWSQVDVGGFES
                     FDGLDLWLAGAADDFALLVATDTARESGLVPPGTRLGAKAIVDGASFAYRTSRPTSEER
                     TTFEFGVFAHGPDADRLAEQYVELIRTWDREHRHGPGARIEVVPAEVPLGALPAGRVID
                     KRHTRVVISWPAAS"
     misc_feature    25378..25391
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     gene            25381..25521
                     /locus_tag="BN1701_RS34435"
     CDS             25381..25521
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="BN1701_RS34435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_082859937.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.7e-17, bitscore:
                     61.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQSAEQFDLDVRFLDSVPVIPELMTNTDDNCGSTCQSACSNSS
                     C"
     CDS_motif       25381..25452
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSTQSAEQFDLDVRFLDSVPVIPE"
                     /locus_tag="BN1701_RS34435_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       25453..25521
                     /prepeptide="core"
                     /locus_tag="BN1701_RS34435_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-9.50"
                     /molecular_weight="2098.2"
                     /monoisotopic_mass="2096.8"
                     /core_sequence="LMTNTDDNCGSTCQSACSNSSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTQSAEQFDLDVRFLDSVPVIPE"
                     /leader_location="[25380:25452](+)"
                     /alternative_weights="2116.2"
                     /alternative_weights="2134.3"
                     /alternative_weights="2152.3"
                     /alternative_weights="2170.3"
     gene            25588..28557
                     /locus_tag="BN1701_RS19750"
     CDS             25588..28557
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024583.1"
                     /locus_tag="BN1701_RS19750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_054050994.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.2e-187,
                     bitscore: 622.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-17,
                     bitscore: 63.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-18, bitscore:
                     66.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGVVDAAVVRVAAHPITTDIPPWPQLTGPDAENVAGWRAWLAAV
                     WAIESFAEAVRTASPTLAGRVAAVCGGQELPARQVRRAVVSVMRYLLRATTRATPFGLF
                     AGVATARFGQVTTVRRVQDAKVVTRVDPVWLAQVVARLEACPALLARIEVVVNDSVRER
                     DGRLVVELRPDPGGVAEPAEVSVRLTRAVRIVMRAARSPIRVAAISDLVCAEFPDTSSD
                     AVDGLVRELVAQRILVTGLRAPMTVTDPLGYLLANLCAAGADRVPEIMPLVAELRAIYT
                     EMTGGRRARAASAMAKIAVADRPVHVDMRADLDLVLPQIVIRETVHAARVLTQLTAHPF
                     GHPRWRDYHHRFLERYGPGAAVPVLDLVDPDVGLGYPAGYRGSLFDRPPPLLSDRDVRL
                     LALAQHSALAGEVEVTLDQSAVDELTCGVPVAWRPHTELSFRLHATSREAVDRGEFDLD
                     VVGMFREAGTTIGRFLDVFAAAERTRMAGVFEALPTSTLGAVRAQLSCPPLYTRTEIVS
                     RSRTMLGHILPIGEHRDPHPGLVDLRDLVVIGEPHRFVLWSTNRRRPVEPTALNAVEAT
                     NFTHPLQRFLAEVTTSRAATSGPFTWGTAAGGLPFLPRLRHRRTILSPARWVLTAADLP
                     RLDASSGCWADELQRWRQHARVPGTVFVGGGDQRLRLDLTEPAHQALLRDTINRDQRVS
                     LHEAPPADAFGWLDGHAHEIVVPLASTQLPAAPMAEPVHVVRRGDEHLPGSDGWLFAKL
                     YGHPDRHTALLAHLPDLLSTWDAPPSWWFLPYRDPDHHLRLRVRADDPATAARVAAWAR
                     HLRERGLISHLCLDTYLPEKARFGTGPAVAAAEAVFAADSAAATSQRHTDSHALTAASL
                     VDIAVSFHGDVEAGMHWLIDNITTDTPVPLPRHQLAHTLHLTHEADALPPSMPARWAER
                     RHALDSYRDSLATIGREPHWALASLLHLHCIRANGINPTAERLSHRLARAAALTWTRRR
                     "
     aSDomain        26047..26319
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BN1701_RS19750_Lanthipeptide_LanB_RRE
                     .1"
                     /evalue="4.90E-20"
                     /identifier="RREFam001.1"
                     /label="BN1701_RS19750"
                     /locus_tag="BN1701_RS19750"
                     /protein_end="244"
                     /protein_start="153"
                     /score="63.0"
                     /tool="antismash"
                     /translation="VVVNDSVRERDGRLVVELRPDPGGVAEPAEVSVRLTRAVRIVMRA
                     ARSPIRVAAISDLVCAEFPDTSSDAVDGLVRELVAQRILVTGLRAP"
     gene            28554..29756
                     /locus_tag="BN1701_RS19755"
     CDS             28554..29756
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024582.1"
                     /locus_tag="BN1701_RS19755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_054050996.1"
                     /sec_met_domain="LANC_like (E-value: 5.2e-40, bitscore:
                     136.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTDIAEVLAQRLADPTTTTTADNTHRPVPQSLANGAAGIALLH
                     IERARTGHGSPATAHAWLTAATAQGVHRGDQAGLFHGAPALAFATNLAAQATGGYQHAH
                     SDFAAATISITTTRLALAHARIDRGDTPALAEFDLIRGLTGLGAYHLTAHPDHPITTAV
                     LAYLVQLAEPHPTGLPGWWTHLAPYGRRSHDYSDGHGNFGVAHGIAGPLALLAIAIREG
                     VVVRGHIAAINRILTWLDTWQQRTPTGTWWPRTITTDELGTGRTQTTRPGPPSWCYGTP
                     GLARAQQLAAIATNDPTRRHTAETALLDCLTDPAQADQITDAGLCHGAAGLLHTTTRIA
                     SDASVPELTSLLPDLTARLIDQLRRQPAGTELLDGSAGAALALHSLTAQPTSWDRCLLL
                     A"
     gene            29772..30602
                     /locus_tag="BN1701_RS19760"
     CDS             29772..30602
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="BN1701_RS19760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_054050998.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.4e-37, bitscore:
                     126.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPQLPWSQAVLHLTDYTTAEHLAVHRLRPLMTTAEHNNDITAWW
                     FIRKAPTWRIRWLPTRPNGDPVVHHALDDLRDTGLLAGWTMTIYEPETHAFGGEPAMDL
                     AHTLFHHDSHHILDHLARTPEPDQRHELTILLCATLMRGAGLDWYEQGDTWARVAHNRL
                     NTDPISHDTTAMRRLLIADTTPNSPKPRNALNQISGWISTFYTAGEHLGRLSRTGKLHR
                     GLRAVLAHHILFHWNRLGVNYRNQHRLANTATTTILDGLTSPKCRSRSTSRTRR"
     gene            complement(31126..31368)
                     /locus_tag="BN1701_RS19765"
     CDS             complement(31126..31368)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054050999.1"
                     /transl_table=11
                     /translation="MIHIAVRLDGAATTAVALACLVLLHTGPALAAWPGRVRAAWYQAR
                     TEAEHAQLAYLRVAAAHVGTDELPVGVRKVPPLDN"
     gene            complement(31365..32204)
                     /locus_tag="BN1701_RS19770"
     CDS             complement(31365..32204)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157368093.1"
                     /transl_table=11
                     /translation="MPKTPPTSPPSAVSRVPLDLPRMPLPGLAVVGRDSVAASGVLMLT
                     HFYVTRLRFFEAVDTARRMLDTDRLWISDKDLLNLLYCWPEHYQRISELHRAQLEARIL
                     GIPHPDVANESRDQIIQGLLVRVLNAFGQPDGRVRRRRADEVDLTSAVSAVRSRLAGSV
                     SGLGTMQIRDLRTQLTAATDILAGLANPLHVRRRSATAKGNVWASLNTLVGQAQRTDGV
                     DMYAAAEQARAWRRIWLLLENHAGGPPSKGQRRAAMLLRPAPSWQPGKPGAGLETVR"
     gene            32555..33949
                     /locus_tag="BN1701_RS34440"
     CDS             32555..33949
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025885.4"
                     /locus_tag="BN1701_RS34440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_157368094.1"
                     /transl_table=11
                     /translation="MTVENGRRTVRTGRPSGEGAAPRLCISAEPDDTTADAVEDLADEG
                     GRVLVIAGARGCRARMCWRLLSSGACDVVSWAPQNNPGAAVVARLARWAEVDAEVSSDL
                     VRGQLVGRSAAWTAALRHVVEVARFTRTTLLVTGESGTGKELVARLFHHLDRRQDKGDL
                     VVLDCTTVVPTLSGSEFFGHERGAFTGAANARDGAFAAADKGTLFLDEVGELPMPLQAE
                     LLRVVQEGTFKRVGGNTWHATNFRLVCATNRDLDAEIRAGRFRLDLYHRLAANRVALPP
                     LCERRGDILELFNHFLAKESGGRVPQLDPAVCALLERRDYPGNVRDLRQLAVRIAARHV
                     GPGPITPGDVPDEERPIDLPAEGDRTIRVLLEEAVGAALKAGRGYREIRDSAADAAVRL
                     AVRRCGDDLQQAALQLGVTDRMVQKWRAQSRTDRSEATARCPDAHAAPAARASSGSDAL
                     RSLVDP"
     misc_feature    32912..32914
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(33861..35312)
                     /locus_tag="BN1701_RS19780"
     CDS             complement(33861..35312)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="BN1701_RS19780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_231949654.1"
                     /transl_table=11
                     /translation="MLLDDPFAAAGLQAETDPGGGGPGASPPPSAEQLALLRTFLGRNV
                     AGAHWRMANFLVPPGLTRRTLLWYRALARGALVNPAKATPVARAVQTLRLRLVDRALDT
                     VTDQEHREMASPRADRRFPAYVRWVQNSLNGLTSAGLAADGIMGPLTRGAVRSFQRRRR
                     LVPDGIVGPLTERALVDAGATSPPRPGRPQPSRRQPDPVAPRSPGSPVSPVVFPPCVEV
                     PAVTDTRSCGEALIQPTRFAGLAAVRDFARSLAACYAERTLAANPRAGAPDAARYLAYL
                     DNDFAGTIRGAHGRYGDRRGLAEIARGWMFGQSERLEFQTRGTAGRRLVDFAPPSKPAG
                     GDALEPIELPGTGTPVQALTNRFLRALRGRHRTVTAGNYAGHGGGSFDSRGYSVDLFLP
                     PPLDGRGFYRPAEAITLLLAVNAAAADVGVRWRALYNDYSVAEAINRHTGVRNVVFMGQ
                     PRTGARPNLNWHGPLVLHVHLDIAP"
     gene            complement(35387..36295)
                     /locus_tag="BN1701_RS19785"
     CDS             complement(35387..36295)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="BN1701_RS19785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase family protein"
                     /protein_id="WP_197672118.1"
                     /transl_table=11
                     /translation="MLRWIVPVVRWGPNGLSIGDWCSVWADYPVVDCHCHAGTGDGLTG
                     PWDTSAPLRDYLRRASAARIDGTVLFAPFSSDYALANAEVARIVAARPRRFVGFAFVHP
                     ERDRGRVAELVSHAVRGYRFLGIKAHRHDGRLTREVCAVADRWRLPVIYDVMGDVAPIE
                     MFAGQYPRVAFVIPHLGSFADDWRAQRAFIDVLARHPNVHTDTSGVRRFDLLVEAVRRA
                     GPHKVLFGSDGPWLHPGVELAKVHALDLTAEAMRLVLGGNVLRLVARVRTGTPLPAHPP
                     AGRLPADTDPWDRLVRLGRTD"
     gene            complement(36377..38257)
                     /locus_tag="BN1701_RS19790"
     CDS             complement(36377..38257)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054051009.1"
                     /transl_table=11
                     /translation="MSSKTFTLRGFPKDPVQVGTTVRLEALVSGKLADAGRYRVDWRIV
                     GPRSDDEQQLSDRGPKIDFAPGAPGAYTVYATRSERDAGIPTGDIGGDIGGGEDGDLFD
                     GGTGGAGDTALPNVVRAARYDGPDNLETDGWEITAQLTGVVSPEGTVPVSLQRTGVTPT
                     SDQVLWTIIRNRTNAIAFRHYKQFIDGVMCRAVDVRNRNGTGHVLNFTGTQAYQVLKQA
                     TDAFLMQECGIVEGDACSTPTAFLDPELMEHELASGSLEATRFLGEEPHRYGRSRPVTL
                     DDLRTMRGLYYDRLGEDGAITLPYLRVIRDRLSDIPLKSPGEITDNCYGILRSRLTGPL
                     AMELIWSYWHEEGMLVQAINAILARFQNRRTVHGVDPLARFDLDPLRPLANLFWGWAED
                     ELHRLTVRRRAFEYDHEYGLTLLGRAVSRQATVDSRSRFVESFHTLLHNCSLFFKEDDD
                     TTVLADGFPLLNALRETHLILAEGAHNQFGDLPSAARAEMLIMEWLLARPEMREFLGGR
                     AMVPYEEEWMDRVDTMKQLQGWANTSVTHTRDMGVFGEQLLLGIRYGNWSVVNDPQQAA
                     NWARYWRPEIQRYTHAYRATTGVDLTERVDATVPGFLLRRRMDVHMRTIR"
     gene            complement(38280..39581)
                     /locus_tag="BN1701_RS19795"
     CDS             complement(38280..39581)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054051011.1"
                     /transl_table=11
                     /translation="MNSQPATPAAFLEQEARALLTRLDRVRPFVLHETMVSAAAPLPSA
                     LSAVERFLLDGRAVLRDQVTEYLRWLAGPGRAVAPSEQQQRFALIRMAFNDILNQFDLF
                     TEAITQRSEFQTGVWLSGLDLLATDALRLPGGYFEPPPVICYLARGPGAAIRRARTRLP
                     GGGSNPVALIRVPRERMIGHGIASSLVHEVGHQAAALLDLVGSLRQTLRAAQASAVGPA
                     GAAWRSWSRWISEIVADLWSVAKLGIGSTLGLIGVVSLPRWFVFRPSGDDPHPVPWIRV
                     QLSCAMGDALYPDPQWRRLAAMWSSLYPLAQAPAGLASRLAALLGHVPAFIDTLLDHRP
                     PALGGAALGTALHLPDRQRAELETNFRAWPHVPQALRDAPPALVFAAVGQARADGVISP
                     EQESHLLGAQLTRWAVRSSLDTSVLCARASTLPI"
     misc_feature    complement(38289..38291)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(39595..40389)
                     /locus_tag="BN1701_RS19800"
     CDS             complement(39595..40389)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS19800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054051013.1"
                     /transl_table=11
                     /translation="MSAFETQEWEGFETPGEWEALEWGEMGQLESQEHTLGEMFGGEME
                     SLGEMQEFELANELLEVASEEELEQFLGKLLRGAAKAAGGMLRSPIGRALGGTLKGVAK
                     AALPMAAGALGNMVLPGIGGMVGSQLGSMASKMFELELEGLGEQEAELEVARRYVRFAT
                     AAARNAARAPSGAPPRAVVRAAVLSAARRHAPGLVRRPPGRWNSPHGPRQGGYGFGADG
                     ADGIEPSFMDSDADLDATDATSGTAQTGRWVRRGRKIVILGA"
ORIGIN
        1 ctggcctggc cagtccggcg ccgccaccca caagagcggg tacggatatc gtgtggtggg
       61 gcgcgctgaa cggcgggacc gtggccagtg ccgggttgtc ggtaagactc cgggccgcgg
      121 agtggatcgc cgcgctttcc aaggcctgtt cgactgtgag cggcgggagg atccccgcga
      181 ggctcttcgc gagcgtcgtc ttgcctgatc cgacgggacc gacgaggaga acatgatggc
      241 cgcccgcagc ggccacctcc agcgctcgtc gggcctctgc ttgccccacg acgttggcaa
      301 gatccggtgg atctgccgga ccgttcctcg tggcgatgtc gggaacggcg aggacatcac
      361 cgtcaccgcg gagccagccg aggacctcgt tgaggctcgt cgctccgcgc acttccaggt
      421 ccggaaccag tgccgcctcg ccgagcgcgt cggttgggac gaccgcgcgt cgaagtccgc
      481 tgcgccggac cgcgaggagg cgcgggagga cgcccctgac agaccggagc ttgccgtcga
      541 aggccagttc gccgatcagg gcagcttcgg cgacacggtg aggcggtact tcgccgtcgg
      601 cgacgaggac ggcgaccgcc agcgcgaggt cgaacgcggg gtccgcggtc gttgccgcgg
      661 acgagacctc aaggacgacc gtggtatcgg gccagcggac acgactgttg cgcacggcgg
      721 ctcggatgcg gtctttggtt tcctgtggca cggctgcgga gttgccgacc gtcgttgtgg
      781 ttggtggccc gtcggagatg gcggcggcga ccgggacggg gacactgtcc acgccgatca
      841 ggcccgcgga ccaggcggct gcgatgggca tggcgaagct cctttggtta gtggtggaat
      901 ggcagcccgc gaatgcgggc gaacgaggat tcaggcgtcg aaacggcgcg gggacttcgc
      961 cccgttgcgt aggccgtcgg cgatggtgcg ttcggcttcc ggtgtgggga agtcggtgag
     1021 ctgggctgcc gcgtcacgca gaccgtgatg gacagcggcg tacgtgtact cgccgcccgc
     1081 gacgaggcgg cccagcgtgt atgccgcgcg caccaggacg tggtggcggc ggccgtgctc
     1141 ggctcgggcg acggtgtcga ggacggtgtt caggtaggcc tgtctgctct gctcggtcac
     1201 cggctgggtc cgaacggccg aagtcgggat caccggcgat ttcatgaggg gtaccagcca
     1261 ctgcggcagc ggcgcgatcg gcaggtctcg cacgacgcgg tacctgcccg ccgcagtgat
     1321 cgagcccgcg gcgacgatgt agccgcccgc gccgcgcgtg tcgatccgcc acccgagccg
     1381 cgcgaccgtg ttgcgcagct cgggttcggc gggcgcacgg aagtacaggt gctctcccgc
     1441 cgagggggtg ccgatggcca gggtgtcgcc ggggtacgac tcgccagctt cctcggccag
     1501 tcttgcgaga acgtcacggc catgcgccgt gccggtccac aggtcgggcg tcgcttggcc
     1561 gtgtgcgtcg tcgaggtcga gtacgtggag tccggacggc ccggtggcga ttccgatgtt
     1621 catcggagcg cgcgcccacc atgccctgat ccgctcgggt tccctggtgg cgcgttcttc
     1681 ccacccgagg tgtccgtcca cacaggatcc cgtgcgtgga caaccggctt ctccgtgcag
     1741 ggcggggatc ttgctgcgtg ggcgcagggg gatcacgaag tggccgtcgt tggcggccgc
     1801 gagcgcgagg cccatcaatc gaggtggccc cactttgccg tgcgctgtgg actgcgtgtc
     1861 acgctccatg cgtcatctcc ccaggtgatc gagcgtacgc cgacatcggt cacgttcggg
     1921 cgcggcgaag gatcgcccgc atctctcgcg gcgagatccc gtactggaag gctgctccca
     1981 gcagcggtgc cagtgtgtcg tctgggtcgg aggtcaccgc gatctcctgg gcgatctgcg
     2041 tgagcgcacc ttccccggcc aggtatgtgc cgatggccag cagacaggcc gggaaggacc
     2101 gctcgggcgc gggaagcgcc cgaacgagtc gcgcccatgc gtcgttcgtt gacctgtctc
     2161 gcggaatgtc gtcgctgacg aggcaccacc cgcgaacgtc aggatcgtcg agggcgcggg
     2221 cgacgcgcgc caatgtgtcg tcgtcgaggt cggtgccgtc gttggtcgcc gcgatcacgc
     2281 ctttgatcag atcgtgaccg gcttcggtgg cgatgtcagg ctggtcgcgt agctgggtga
     2341 tgagttcggc gcggcgacgc agagcttcgg cggggtcggg tgccaggctg gcggccatgt
     2401 cggccctgga ggagaacttg gggatgcctt cgtaggccgc gtggaccgcg acgagggtgg
     2461 tgtcggggtc ggggaccaca ccacggtggt cggtggtgta gctgacccac cgggcgcctg
     2521 ccctgacgtc gggcgaccac actgcctcgt ggatggtgac cctgaggtct ttcagcctgc
     2581 gagtcagcga ctcgaccagg ccccggtgtg gaaggtcgcg gtcaggctgg ccgccgatga
     2641 ccatgacgaa catgtcgtgc ccgtgttggg cggcgaccga tgccatctgc gcggcgagcg
     2701 actcgcagtg ctcgggcgcg ggtaggtcca ctcggatgca gggtccgtca acgacataga
     2761 caagcaggga gtcgactggc gggtatccga ggaaggtcgt catggcggcg atcagctcgc
     2821 cgagcgggat ggtcggtgtg gtgaactgcg cggtgtcgtc actggaatca ggcatgtcgc
     2881 gtcctttatg gaggttgggc ggtggatgtg gtcgttctcg ccgctcagat cgcggcgagg
     2941 actggggtgg acgcgagaac ggcgtccaag gtggcgaggg tgccgctgtc gagggtctcg
     3001 gcccagttgg tgacggtgcg ggtgaggttg cgttcggcgc gggagacgcc gcggacggtg
     3061 cggtagtggt gttcgaaggt gttgaccgcc tgcagcacgc cccacgctgt gccgcgccac
     3121 ggcgacaccc gctcgtcgtg gtcccaaagg cggcgcagct cagcgcggtg cgtggccacc
     3181 aaggtccgcg agcgcttgct gtccgacttg tccggggcat gggcgcggac gaactctcgc
     3241 catgcggtgt cgttgacctc gactcggcac agttcggcga tctgggtggc gtagtcgtcg
     3301 gcgaggacct ggaccatgtc gagggcctgg cgggcggtga ggacttcgaa cttggcgttc
     3361 ttggagtgct tgaccttgat cacctggccc gcaccgcgca gcgcggcgcc tagggtgttg
     3421 tcgcacacga cattggtgat gctgcgcttg taggtggtgg agaggctgcc gtcgtggctg
     3481 gtgcaggcga tgaggtgcgg gcggaacacc acaccttccg gtgtgcggac gctgtcgggg
     3541 acctcgacgg acacccatgc ctgggcgcgg ttcttcagca gtccggcgga cccggcacgc
     3601 aggccaccgt ccaggaccgc gtcgaccttc tccagcaacc attcctggta ctggtgaatc
     3661 gcgtagcggt cggtgtggat acccaggtcg tcaccggtgt cgctggcgac caccgctttg
     3721 cgggtgggcg cggcgcacaa cccgtgttcg gcggtgtgga tcagcacgcg gcctgggata
     3781 gcgtcccagt tgaacagtcg gcgttggatg tcggcgatcg ggatcgggcc cggatagtga
     3841 ttcggttcgg cgccttgggc tgaggcccgg tagtgccacg cgcggccgcg cgcttcggtg
     3901 aagccgatga ggacgttgcg gttgagccac gtggctgttt cggtcgacat gtcgttgcct
     3961 ttctcctcgt gcgtagaacg gcccggccct ggtgagttac cgggccgggc cgtgtgggta
     4021 ctcgcggtgg tgctgttgtc agttgttctc ggtgatcgtg atgaggtgga cgtggagacc
     4081 ggcttcagta agttcggcca agacccgctc gatgtgcgcg ttctgggcgg cgtggacgcg
     4141 ggcctcaagc catcggaaga agcgctcggg cagcggcgcg ggcacgccgt catcgccgag
     4201 ggggccggtg acgacgcagt ggcctcggat ctgcggcgcc cagccgtgtg cgcgcagcgt
     4261 cttgatccgc gactgggccg cgtcgctgac cgcgaggtcg ccggtgagcg cggcctcgat
     4321 caactcctcg atcaggatca tcgcgggacc gttgatcggc gcctggctgt cggccaccgc
     4381 gccgacccag aactcgagga tgccgagttc ggtgtcgacg gtgctcgggg cggtaccgcc
     4441 gagcagttcg gtaatggtga cgagcgggtc tgggccgagg atggctatca ggccctgttc
     4501 gtgcgagatc gtcaacgcga acggcgggtc gacgggctgg gcggactggg gatggacagt
     4561 gtggtgcact tcgtgttcct ttcggtggag gttcaggcga cgtcgttgtg cgcgcgggcg
     4621 gcgaggagat ggctggcggc actacgccgg gtctcgcgga caggccggga actgtctgct
     4681 tcggccgtgt ggccaaagca cagacgactc cactgtggac agatgggcga gatgcccgcg
     4741 gcacggacta cgtcgccgtg acgaccgctt gtcgagtgga tctgttcggt gtccgcctgt
     4801 ccggctgggg cgcacttcgt cgggatcggc gccgggggtg gtgtcaaccc ctagcggagc
     4861 ggggttgaca ccacccccgg ggtcgatcac ggtgcgccgc cccagccgga caggcggaca
     4921 ccgtgccgat caacccaccg cacgcctgta acacatggtt acctcgaacg ggtctacttt
     4981 tcgcgattca cgcgtttccg cagttcaaac acccgctatc attgactctg agtagcgacc
     5041 gtggcgagaa tgggttgatc gcgccgactg gggagtcggc tgtccgggag ggggctcggg
     5101 atgagggtgc gggtagtgga aggtgctggg cgccggcgac tcacggaggc gggacggccc
     5161 cgcactgggc tacgctcacg gccgtgacct gcgcgaatga tcagcgatga cgggccattg
     5221 agcactgtcc accctggatc gccgggcgac ctgacgacat tcgtcggccg ggcggatctg
     5281 ctcgccgagg cgaccgagct gcttctcggg ccgggcaggc ggttggtgac cctggttggc
     5341 accggcgggg tgggcaagac gcggttggcc agagagctgg cggcgcgggt cgtcgacacg
     5401 ttcgcccacg gcgcggtcct ggtggacctg accgatgtcc gcgccgcgga cgaccgggtc
     5461 gacgccgcgg ttatcgaggc ggtgggcttg ttggacaacg cgacgtcccc ggctcgggct
     5521 cggttgatcg agcacctgcg cgacaggtcg gtgctgctgg tcctggacaa ctgcgagcaa
     5581 ctggtgagtc tggacggtga gggcgagttg ccgcggttgg tcagcaccct gctcgccacg
     5641 gcgccggggg tgcggatcct ggcgacgagc cgggtcgcgc tgggggtttc gggagagcgc
     5701 cgtgtgcgga ttccgccgat gtgggtgtcg gccggtgggg acccggatgg ggcggtcacc
     5761 gaggcgctgg ccctgttgct ggaccgggcc gacgcctacg acgtgacgat cgcgcagtcg
     5821 gactatccgc tggccaacga gctgtgtcgg atgttggacg gactcccgct ggccatcgaa
     5881 ctggccgcgg gcaggctcga tgtgctgacc ctggacgaga tcgtcgaccg ttgcgaggac
     5941 tcgatgcggc tgctggtgcg ctccggccgc gccgagcagc gacaccacca gaccttgcac
     6001 gcgacgctgc gctggtcctt cgacctgctc ctcgagtccg atcagcgcat gtgggtcatg
     6061 atgtcggtgt tcgacggcgg gttcgacctg gccgcggccg agggcgtgtg cgccgctcac
     6121 ggcgtcgact cgggcgaggt tctcgacctg ctgacccggc tggtccacgc ctccttgttg
     6181 accacccagg cgcggcgggg ccgcacctac tatcggatgc tcgaggtcgt ccgccggttc
     6241 ggccatgaga tcgccgatcc cgacgagctc aaccggatcc gcgactcgca cgccgcctat
     6301 tacggcaggc tggtcgaccg tgcggcgcgc gagtggtacg ggccggacga gtccgagtgg
     6361 atcgaccggc tgcggcggaa cctccacaac atccgcgccg cggtcgacca tctcgtcggt
     6421 cagggcgatt ggatggccgc gttgtcgatc gcgtgcgatg tgacccggac gcgaacccac
     6481 atctgcgtgg gccagatcaa cgaggcgcgt cgcctgctgc gggccggtct gaacgcccac
     6541 cctgaggagc cgtcggagct cgaggtcacc gcggtgtcga tgttggcgta tctggcgatg
     6601 ctgcagggca gccgcgagga ggccgacccg ctgctggacc gtgccgagcg ggtcgcgacc
     6661 gcgatcggcg cgcacgcgag cccggcgctg ttgttcgccc gcggcatgcg cgactggctg
     6721 gtcggacagt ccaacgaaga agcggcgaaa gccctgacca cgctgaccgc cgcgatcgac
     6781 accctcggcg acaccgagcc gagcgagcgg atggcgatgc tgatcgtgct ggccatcgcc
     6841 gccagcgtcg acggcaccga gccagccgcg cgcgagacag ccgaggcatt ctgggccgag
     6901 gtcgccgagt ctggtgtgga cagcgtggtt tcgtgggcct tgttcgccaa gtcgattgtc
     6961 gcgttgcggt tcggcacgct cgcgcaagcg cttgatcttg tccagcggtg cctgcgtctc
     7021 caatacccga gcgaggacac gtggggccca gcgtggtgcc tgtggctgcg cgcggtgatc
     7081 gccgcgcgga tggcagacca cgtcgtctcg gcgcgcctgt tcggagccgc gcacgcccgt
     7141 caccgtgcga ccgacgtctc gatgagtggc ctgaaaccct ggtggcggct ccaagtcgac
     7201 gccgaacgca acgtccgccg cgcgctcggt gaggactatg acgtcgaagt ggcggtcggc
     7261 gccgcactcc cctacgacga agcgatggtg ctcgccctgg ccgtgccgac cgagaacggc
     7321 gacggcgccg gcgccggagc ccacgggctc acccagcgcc agctgcagat cgcgcggctc
     7381 gtggccgacg gcctgacgaa caaggagatc gccgccaagc tcacgctcag cacccgcacg
     7441 gtcgagaacc acgtgctgcg gaccatcggc aggctgggcc tggacgggaa aggtaaacct
     7501 gggctggcgg cctggtacgc cgagaacatc cacgcagggt cacccgcggc tacgccgaca
     7561 ggttcgctgg cacccagatc gggttgatcg ccgcgcgggg gcgaagccgt gtcggaggat
     7621 ccgccagtga tcgaaatggg cgtcgtggag aagtatgcgg cacactatct gcggtaacac
     7681 tgggaggcgg ttcgagtggg cgcggtgcgg gcgctgccat cggcggcgag tgtgcggttg
     7741 actgacacgg tggccgcgtt cctggacacg atcacggtgg ccaacacccg cgggtacgtg
     7801 atcgggttgg accggatggt gcgcgacttc ggtgcggact tgaatgtgcg gctgctggat
     7861 ccggcccgcg ccgagaccgc accggaccca gcagaagtcg acatgcccga agacccgcac
     7921 gaggcggagc tgcggcacaa cgccgcgcgg ctgctcacgg gcgcctgggt ggccggtcag
     7981 ctcacggcga tccccccgcg tgcctggccc gaggatttcc cccggcatcg cctggcggtc
     8041 gccgcccgcg cccagatcca gggcgagatc gacgagaacc tcgaccagcc cggcgagtgc
     8101 cagggcgccg agggcggctc ccggtgagcc gcgcgcgcac ccgttcaggt gggttcgtcg
     8161 agcaagtccg gctcgatccg cacgcggaca ccggcagcta cccgttcacg ctgccgatcg
     8221 tgcgccacct cgaccgggtc ggcgggctgg agctggaccc cggggtgacg ttcctggtcg
     8281 gcgacaacgg caccggcaaa tccaccctgg tcgaggcgat cgccgtggcc gcggggttca
     8341 acccggaggg cggatcccag tcgttccggt tcgccacccg cgccaccgaa tcgtcgctgg
     8401 gcgatcacct gatcctgcgg tggggcaccc gcaaaccgcg caccggattc ttcctgcgcg
     8461 ccgagtccta ctacaacgta gccagcgaga tcgagcggct ggaccgcgag ccgggcccgt
     8521 cgctgctgcc ggcatacggc ggggtgtccc cgcacgaacg ctcccacggc gagtcctttt
     8581 tggacttggt gacgcaccgg ttcggcccca acgggttgta tctgctcgac gagccggagg
     8641 cggcgctgtc ggtgaaggga tgcctggcgt tggtggcgcg gatggcggag ttgatcgggc
     8701 agggctgtca gttcgtggtg gccacgcact cgccgatcct gctcgcggtt ccaagggcgc
     8761 ggatcctgca ggtcgacggc gacggggaga tcgaacaggt agccttcgac gaggcggatc
     8821 cggtcaccct gacccgtggg ttcctggatt cgccgcagcg gttcctgcgt catctgctgg
     8881 ccgatgagta ggccgggcgc gtgaccggat cctggtggtg ggatctggtg atcggcgtgg
     8941 cggtggcgtt gctggcggcc gtgatccccg acttcatccc aatcgtgggc tacgccgacg
     9001 acgctgtcat cgtcaccgcc gtgctgcgcg ggaggtccgc cccgcggggc tcgacgcggt
     9061 gcgcaggcac tggcccggaa ccgacgacgg gttcgccgcg ctggccaggc tcaccgggct
     9121 cacgccgagg tgaggcgggc caggacctgt tcggcgttgc ggtgcaacgg aatcgccatt
     9181 cccggatagt cgccctggtc gacacgcatc agcatccggg tggtggcgta cagctgggcg
     9241 agcagcccgt cgcgggtgtc cagcaacagg ccgagttcgg cgcggacggc ggccgcggcg
     9301 gcggggacga gcagggtgtg cacgtacagg caggccgcgt cgtagccggc tggggccgtg
     9361 ccccagccct cccagtcgag cagggcgcac tccggttgca gcaggttggc ccagtgcagg
     9421 tccccgtggg ccgcggtcca ggtgttgacg gtggtgtcgc ctgcacggtc gccgaagaac
     9481 atctccaccc gtctgctcag gtcgtcctgg ccgagggcga tccgggtggt ggcggtcgcg
     9541 gcgactgccg cgagcgagga ccacaacgct tcccaccagg ctggggccac ggccagcggc
     9601 tcgcggagct cgggggtggg tgagcaacgg gcgccaggca tcagggtcat cagttcggcg
     9661 cgcaccgccc agtccccgtc ggtgaggtcc cagtgccgca gcacccacgg cttggctacc
     9721 ccggttacgt cgttggcgtc ggcgttgccg gtccagaacg ctccgcccgc ccagccgtgt
     9781 tgctcgatga ccagccgcag ccaccgcggt ccggccgctg tggcgacccg ggccccggcg
     9841 gaccggtcgc gccagccgaa taccaacgcc ccgtcgagcg tggcgtcggc ggtggccgcg
     9901 gccttggcgt agacgtcagc cagccacgcc cggtgcgccg cgtccgccgc ggacagctcg
     9961 ttctcgccgg tcataaagcc caggctaatg ccgccggtga tcagtagcgg ggccagcagg
    10021 agttgggttt gcacctgacc gggtcacagg tcgggctgca ccgcggtgag caggtcggtt
    10081 gacagtgcgg gttgcaggac ggtgtgcagt cggggttgca cggctggttc ttcggcgcgc
    10141 agtccggctt gcacgcgctc ggtgcccgcc cggcgaacgc ggcggccagc tcggcgcgca
    10201 ccgcgtcggc ggctgggctg tccaggatct cggtgagctc gtgttcgagg acattgccga
    10261 ctggcagcca gcgggagaac acgcacggcc acaccgcccc gtccggggag atcgcggcga
    10321 cgccgtcgcc gcagttgccg cacagctggt cggtgcttgg cgcctggtcg cggacaccgc
    10381 gaccgacctg gcgcagccgg tcatagccga ccgccgggac accgagatcc accaactcgg
    10441 tctgggcctg cgtggcgcgt tggtcgccgc ccatgtcgat cactcccgcc cggagcggga
    10501 tgccccggcg cagcgccgct gcgatgttgg ctcgggtgcg ggcgtggctg ggccgccggg
    10561 tgacctgcgc gtgctggtcg gggtcgtcgg agtagtagct ggtggccagc gacaccccgg
    10621 gccgggtgaa catctcccac agcggggcag tgacgtggac gaggttggtg aacacctcca
    10681 cctccagccc ggccgccagg gcatgggcga tcagctcccg caggtccggg tgcagggtcg
    10741 gctcaccacc gatgaactgc accatcccga ccccggcggc cgcggcctgg tcgatcaccc
    10801 gcaaccagtc ggcgcgggtc atcgagccgt gcgtccccga cggcccggat ccggcgtagc
    10861 agtgatcgca ttcgagctgg cagaagccag tcaattccag ccacaggaag gaaatccgcg
    10921 ccacgccagc cccctgatcc tcggtccggt caccgccgcc gatcagtgtg acgcagagaa
    10981 ccgacaagat caccccacgc gactcgaccg gctcagtcgt ggcgggcgag ttcgaccgcc
    11041 gagatcagca ggatcacgac agcgcgggga tcagcacgaa gtccagcatc aggccgccga
    11101 ggagggttct agtgacggat ccggcaacca ttgacggctc gccgcagcgc gatggggcgg
    11161 cgagttcgtc ggtgaggctt gtcgagcgca tggcccgatg atgcaggatg tcgagctgga
    11221 tgtggctagt cggtgtgctc gatcgtatgc cgtcggagat ctccgtgccg cggctgcccg
    11281 aggtcgactg ggcccaacac gagtggcagc gcgagcaggc cgttcatggt cgcactgggt
    11341 gcgtgcctgg cgacgacgtc gagcagtcgc accttggggt accgacgcgt catactccca
    11401 agcgccacgg tggctgcgac tcgggacaac ggcgcgccga agcaatagtg cgcgccatgt
    11461 ccgaagctca gatgggagtt gggtgaacgc tcgaggttga gagtggcggc atccgggcat
    11521 cgaacgaggt ccgggtcacg gttggccgcg tggagccaca ccaggacgat ctccccggcg
    11581 gggatcggct ggccgccata ttcgaccggc tcagtcgtgt atcggtgggt ggtcatccgc
    11641 atcggcgtgt cgaaccgcag gatctcctcg accgcggtcg ggagcagcca gggtgactcg
    11701 cgcagccggt tccagctgcc ctggtgcgag agcaggcgga acaccgcggt ggtgatcaga
    11761 ttggccgacg cctgaaagcc ggtcagcagc aggaacaccg tgcccagcag ttcctcggtg
    11821 gacagacagt cgcctgcgtc gcgtgggtgg atcaacaccg acagcaggtc gtcgcccggt
    11881 tcggagcgct tgtgatcgat cagcgtgttc agataggagc tcaatgccca ggtggcgcga
    11941 acggtccgcg gtacgtcttc ctccatcagc gccgtcgtcc actcgctgag cagctcgcgg
    12001 tcgcccgagg ggatccccag cagatcgcag atcacggcga gcatcagcgg acaggccagc
    12061 gacgacacga gatcgaccgg ttcgtcgacc ggcagcgcgt cgagcatcga cgcggcgagg
    12121 acctcgatcc tcggccgcaa cgcctcgact cgggcccgcg tgaactccag accgacgatt
    12181 cgccgcaagc gcgcgtgatc gagcccgtca acgaacagca tgtgcgtgtc gagaatgccc
    12241 gcgacctggg ccatgtcgcc gagccgagtc tgttgcccat caatgatggc gtggatcgtg
    12301 cgtgcgtcct tccgcagccg tgggtcagtc agggcgcgct tggcgtcggc gtacccggtg
    12361 atcacccaga cccgcacgcc gctggtcaac gtcgagcgat agaccttcga ctgggcgcgg
    12421 agcgagtcca cctcatccag tggtcgatcc cagaaaccgt ccgcgaacag ttcaccgccg
    12481 ctccgtggct ccacagcgcg tgtccctcca ttggaccttt cgccgcatcc ggccccgaaa
    12541 gcacgccctg gacggccagc acgaggtgag ttatgcgtgg ccgccagggc ctgctctccc
    12601 ccagcgagtg accagcacct gacccacccc catcgcggca tcggttcgca ggggcgaatc
    12661 cacaccgcgg gtcagttgcc gaccacattc attcggtatt gcaggttcca gcatggcccg
    12721 agagctgctc cagcgccatc cgaaattgca ctcaagtgga cccagacctc attactcaac
    12781 acccagtcag attgagtaat gaactactca agccaggcgc agattgagta ctcgaccaca
    12841 aatgcctggc gtcgacgaac gcagaacgtg catgcccttt gagtacaatc aaccgtacta
    12901 acccgataag gtgatttcgc agagagttca gtgacaatgt cgcctaccaa tagcctcgtc
    12961 gcttagattt gaaattgccc gtggggggcg aaaggcgttg actgggggcg aaagatgtcg
    13021 acggcacaag ctaagcatca cgggcgggcg tccaacgaac ggcgccgtgc tcggtggacg
    13081 gcaacggaac gggccgccgc acaggagccg ggatggctgc gggcagcgtt gcgcgcgggc
    13141 cagggcaccg gcgaggacgc aggcgttcct tccggcctgc ttcgatcacc ggccccggcc
    13201 gtcacgattg tgcggataag gtgcggcgga tcacatgtct cggtcgccct ggctcatggc
    13261 tatgcctccc ttcgcggcgg cccacgctcg ggtggacacg agcgcgcggg aagtgcggcg
    13321 acccgtgcag gcgaacggcg cggatcccgc gacagccgtg cacggcacgg gacgccgggc
    13381 atggctaact cccatccgct gctcggtgtc tccgatgcgg gggcaggtgg cggcaggtcc
    13441 ggtgggcctt gtctgccgcg gtcggggtcg tgttcggacg ggccggggtc agcgtgtcac
    13501 gcagcgggtt cgtcgtgaag ggccgtacgc gggacaagaa ccaagaacaa agtgacagtc
    13561 tgtgggacct tggcggcgcg accatcgcgg tcgtgctgct catcgacctg atcggcgcac
    13621 tggccgtcac cgcacgcgcg attggcgccg cgccgccaag gctcgccgat tggttgttgt
    13681 tcctggcgct actgaccgcg gccatcgtgt acgtgtggct gacccgcccc gtcgaagagc
    13741 gcaggcgcgg tgcccgactc gcccaacgca cggtcgagca cgtcgatcag acgtccatct
    13801 tctttgccgc agcagggctg acgctgccga cactgttggc cgttgcgctg gtcgtcgtga
    13861 tccggtatcg ccgtttcctc gtggctcgta agcccatcgg gctgtggacc agcaacacgt
    13921 tcacggtcct gctgtcggtc gtcggcgtcg gttgggtgcg tgatctgatc ggtggtgcga
    13981 cctggctctc tggctcattc gtggcggatc tgagcacggg agtgcggagc ggggtcgtgc
    14041 tcggggccgc gatcgccgtc tactttctag cccaagctgt tcccattggg ctgtaccggg
    14101 gcgttcgatt cggagcgtgg accctggggg cgactctcgg cgcgcgcgag gacaacctgc
    14161 ttatcgtgca cacgctcgtc ttgggcatgt tcgccgcact ggtgactgcg cacgcgccga
    14221 tcttgctgcc cgtcatagtc gcgctggcgg tacgtgacag cagaatggtc ggcagattgg
    14281 ccacgaccac ggccgacgca ttgaccgatc ctttgacctc gttgcccaat cgtcgagcgt
    14341 tcgatcttca tgcgacggtg gcgctcgaga tcgaccgggc aggtcgccaa cccactagcc
    14401 tgctcatgct ggatctggat cacttcaagg catggaacac gacgttgggc cacttgggcg
    14461 ccgaccaggt gctggtcgcc gtggccgata tcctccgcaa ggtcaagagg aaaggagacc
    14521 tcatcgcgcg gtggggcggc gaagagttgg ccatggtgct gccgaacacc gacccgcacg
    14581 gcgcggaaca gatcgctgag cgaatccgtg tcgcggtcga ggaccttcga ctggctatcc
    14641 gcaagccagc gggcggggtg gtcgtctgcc tggggaccgg cggcgtacca aattgcacga
    14701 tctcgattgg cgccgcgacc tccccgcatc acgcagttga cttgcccgca cttcaagaat
    14761 gtgcggatca ggctctcgaa ctggcgaaac agctgggtcg aaatcgagtg gtttccttcc
    14821 agccgcgagg gagcgaaagg gtattgccgg ccgtcgagac ccaggaatcc actaattagt
    14881 ccgttcttct acccaccgct tgacctgcgc gcccgcgctg ttggtccatt cggttgacgc
    14941 aacgccaaca gccgaccttg ccacccatgt aacatagcgt gtacagccaa gttcggaggg
    15001 aaatagaggg ccgattggta gaggaagcag ggagcgtgac tggacagcgg attcggttgc
    15061 ccggcggcga gttcacagcc aatatggttc gcgccacatt gtgccgtcga acagcaacgt
    15121 cgaggagatc caactcgccc atcgtgcgtg ggcttggctt gaccccataa cccgcagttc
    15181 tcggcaacta cccgtagcgc gtagatcacg cccgacgtct cgtacggcag gacccggcca
    15241 cctgctcagc taatggacct cgtcgtccgt cgaggtcgtc gtcacatcga ctcgcacgaa
    15301 ctgaacgaac accgcactga tgagagcgaa ggcagccgcg atcacgaaca cggctacatg
    15361 tccgcccgag gtcgaggccg cgttgagagc gaccacaagg acgagaacct gcgggagggc
    15421 gctcgccgtg ttgaaaacgc ccaggtacgc gccgtgatgg tttcgatcgg gcagtacctt
    15481 ggtgtttaga tggagatcgg tcggggcaaa cagtcccgaa ccgaccccga gaaccgccgc
    15541 cacgccaacg atgagaaccc acctcagcga ggggctatct acaaatgcaa tcgcgatcaa
    15601 gcacatcaat ccggcggcca tcacgattcc cgaacgggtc acgtaacgct ttagtataac
    15661 aacctcacta ccaggcaact tctcagcccg aggcccgaag gataaagcag cagcacccac
    15721 gaagaagctc gtgaccgcca tacttaatac cattgacgga aaagacccta ccttctgtcc
    15781 gacggtcttc aagagataga acgggagata agcgacgcca acggtgaatg cagcctggaa
    15841 cgagaggcgc gccgtaaaag ccattcccat gtttcgattc ccaaagatgt gctcccgaaa
    15901 tatcgccacc aggcgtggtc gacgccctgg tgcggccgtg ctcatcggtg tctcgtcggc
    15961 gccaattagg atcgggatgg tgagcaccac tgccgtaatc ccgacgatga tccatggaaa
    16021 aggcgagtca ggccgaagcg agagggttac gactccccca agcatcggcc caataatctg
    16081 tgcggcgccg aacatcgtca cggctccggc aagctgtcgg cgagtaagct tgtcgaccat
    16141 taatgctaat agcccggcga gcatcgcatt gaggaaggcc tgagcgacgc accaagcaat
    16201 gagaatctgc caccagttgg cggtaaatcc gatcccagca acggccaagc ttccgccgat
    16261 tgagccgacg agaatgaacg gccgccgccg accaaactcg cccgtcgtgc ggtctgacca
    16321 gtacccggcc atgatgttga caatgacagc caccatagcg ccagcagcca ggatccaccc
    16381 gtgttcgaca ctccacgcgt cgggcagcat ggcttgtagg cgcccgggca ggaggagtgc
    16441 gatgggagta ctgaacgcta gccagattcc gtagcctgct aacgcgaact gcaccagcca
    16501 ctttgtcggc acacgtccgc tctcaagcag ctgtctctcc gcctcttcac gttcagcgag
    16561 gcgctcgctc accctttctg atacgaccgc cgacgctacg ctgccaggca acaaccaact
    16621 gagaatcccg agaccgatgc tgcggaccat cttgcgagac ctagctatca ggtttccgag
    16681 gccactaacg gcggtgtcat agttgcccga gcgagtggcc agatatacca cgatgaccag
    16741 gactattggg gcgagcgcaa ttatgacgcc cgggccaagc cgcggcgcca aggcaacgac
    16801 ggccaccacc ggtatcccga gtccaacgag ccagccatca ttgacgggga ggcgcgctag
    16861 gacgatgcct gtcaaacacc agattacggc tccagcagcg acgaaccatt caccgtgatc
    16921 aggtaaagag ccaatccttc cccgcttagc aatctcatgc cacagcacgc ccccaagaac
    16981 aactgctgcg catccggcag caatatgggc gatgaaccat ggagaccgaa tcagatcacg
    17041 gtccaatagc caccgttcgc ggttgggctc ggccgcgata gctggcagct tggaccggta
    17101 tcggtagtga ttccataggg acgtgacatg acttttctga gatcctttac cgacggcagc
    17161 tggcgttgcc agagtcgagc cttcaaagag ccagaccata gtgacattgg cgatgcctag
    17221 catagtagag aatccaaaga atgaggcgag gacctcgggg gagcgctctg tcgcaccgga
    17281 cccaaaccac agacccgcgg tcgcacggag accgtagcct agcccgacga gtagatagac
    17341 aacgtgctcc gggatctttg gcttcttcaa cgcttgagcc gctctacccg cgcgagtccc
    17401 ccttttggta acgacgcgtg ccgcttcata cacgaaagtg tggacaagaa gcgccaagag
    17461 aaaaacgagc ccccaaccga cggcgcttcc acctttgacc aaaagcgtaa ccacggcgaa
    17521 cgcgatgccg aggcgggcga ccaccatgat agccacgagg cgaagtgcgg gatcctcagg
    17581 gtcatctttg ttccaaggta tccggccgcg cgctttagct tgggtatgcg cctggtcgtg
    17641 gtcggcatcc cgcaagtcgt tccacgcata ccgcgcctga tatgcgagcg gttctaaagc
    17701 cacccaaaag attagcgcgt tgatgagggc ctcagtgctt ggatcgtaaa tggcggcacc
    17761 cactccacag gcgacgaggt agtaggttgc cttgatagcg tcagctggtc gcggccaaac
    17821 gagatatcga atgagcgcac gtcgaggggt cgccccggca cccgcgccgc ctcgctcctc
    17881 ggtccatcgc aacaccttcg caaagaatct agtcggactg gaactggtcg accagatcac
    17941 ccacgagatg aacggacagt acaccatctc aaacagcaga attccgcgct cgatgtagtg
    18001 attgtcgatt tcaagggtga gcttgagaac aaccgccgcg ggaacggtca acacgaccgc
    18061 gtatatgaac cagtgggcaa cagtgattcg gttgcgctgg cgtggactgt tgatcgcccg
    18121 ttcgatgctg ccgatagcag gcaaccggat aacgggcgca ggtccatcgt tttctccgtg
    18181 aaggctgccc ccgagatcgg tatttgcgag attggcaatc cgctcctcaa ccgcgcgcat
    18241 gtacagctgc ctagccgttg ccgacgcgaa gtagaccgcg gcataggtac taatggcaag
    18301 cgcgatcccg cagaggagga cgcgaatacc atcatccatt ttgacgttgt ccgagagcag
    18361 caggatcccg ccgagagccg tgaccgcagc gaggatgatc gtcgtatgct gcgtcagagt
    18421 atgccgattg tcttccctgc ccgcctcgta ttcggtgatc agaacgtcga gatcatcgct
    18481 tggcgactca gtccgacgcc agcggtcgag gaacatggca tcctttctac aagcacggca
    18541 atgtcacaag ctggcggcca tctcactcaa ggcggaacga cacgaggtaa ggatccgctc
    18601 gcaggcgcag atcggcccac taccctcgac actcggcgag tcccagacca ccgcgatact
    18661 cgggagcgac atacacttcg gcgagatatc ctgagcgatc tccaggcaag agtgcgcggt
    18721 accaccgcga agaggaatgt ttgtgagggt tgcgatcaat tccctcgctc gacaaatctg
    18781 cgttcgacat cgtcgcgcca aacacgaagc aatctacgac gagggctgcc cccgacgaca
    18841 tgtcagtatc ttcgagcttg catccatcgc gcccgcagaa cgggatgggc tttgacgaca
    18901 agtaggccgg ggtgaagtcc tccagcaact cggtgccaat ggccaccttg ttctggacca
    18961 cgatcgccac cgggcgagag gacggcggcg agacggccgt actcgactga tcctgcgtcg
    19021 gctccgtaac gaaaaaggtc accatgaccg acagcgcggc ggtgatcacc aggatcccaa
    19081 ccccagccag caccagccaa cgacgtcgaa ctggcggtcg ctgccgtggt ggcggaggac
    19141 cgtctgtcgg cgccgcggta tccaaaacgg gcggcgttgg cggcagcaat acaaggcggt
    19201 cgtgacgcgc cctccactcc tcgagctctg gcgcctgcac acctgcggcg gtcagtacgt
    19261 cgatcacgag gtcgagcttc gggatcccgt ccttgatggc tcgggcgatg gtcgacttgg
    19321 cccagccgga cttcttctcg gcctgccgca aggagaggtt gccccgccgt aacgcttcgg
    19381 ccaggtcggc ccggaacgcc tcaggactgt cgatttgtct tcgtccgtcg gaagtgtcgg
    19441 tcacccggca agcatgccga aggcgttgct gcgcccgata gcagcgaccg ggcgatctgg
    19501 catccaccag gcaggtgatc agctgtcccg ccgaatgtcc cgggacaccc tggcccaagc
    19561 gggacaaggt ccgcggacca cgacatcagt cgatcgggac acgcacgtag gacggaccga
    19621 atcggcccag ggacgccaag ccctgtcgac cacaggcagc tcgctgccaa cgtcgttctc
    19681 ggcgcaggca ctcgccgctg ccgctcatcc cgaacccgct ctttaggaga catcatgttc
    19741 aaacgtgcgt tgaggatctt cgcgctagcc atcgccgcgc tggccgcgct gctgctgccc
    19801 ggcaccgtcg ccaccgcatc gaactcgggt gccgacaccg tggctgcctg ccggtacgcc
    19861 acctacgccc cggccaggag cggcagtaac gtcacgggct ggggcgagaa gtgggagtgc
    19921 ggcggcagca ccagctggac catcaccctg cagcggcacc gcggcggcgg ctggtggcag
    19981 aacgaggcac gcaattacgc caccggcgac ggctgggtgt cggtcacggc ggggtgtgta
    20041 ccgggcactt ggacctaccg cacgattctg gagtcgaacg tgggccacaa gaccgtgagc
    20101 tcccacgcgg ctatcagctg ctgatcgcct tgaagtagct cggacgcggt gggcgccgga
    20161 caactgtccg ggccccacct tcactcgatc gtgtcggtgc cttgcttggc caccacgccg
    20221 tcgatgcctt cgccgcaacg aatgcggacg gtgtcggcga gggcatggag gtcatcgaaa
    20281 gtcaatgagg cgcccggctt gcggcgaaag tcttcgactt cgacgacgat cccggtgtcc
    20341 gccagcccct gggacggccg ccacgagttg gtccgcggac agagcgggca ccataccccc
    20401 ggcgtcggtc ttggacatgg cgatggcgcc gcctagaccg accacggcaa cacggcgccc
    20461 cgacagctgg ggatcagaca ccctggaatt ccttcgacca cgtccggata ccgatcggca
    20521 gcctactgcc ggccgtggtg ttcgccgagg ttgccgacgc caggtgagac gccaccggcg
    20581 agttgcccag tgtcacccgg tcgggcagca tcagacctgg gtgtctacgc gcacacgccc
    20641 cgacccacta gtcctgggtc ggggcgtgtt gcgttctact cggtgatgcg gccgtcccgg
    20701 acggccgcga tcagagcccg gccgcgggcg ccggtcagtt cgagcaccgg tcccgagatg
    20761 tttttcgagt cgcggatgcc gaacaggtcg tcggcctggg cgatctcgac acaggaaccg
    20821 ctggcgccgc cgctgaagct ggacttccgc caggctagct cgacgcagga accgctttcg
    20881 cctccgctga agctggactt gcggaagctt gctccagccc aagactcata gatcatagtt
    20941 tcacctcctt caatgcgcgt tggatgatcg cacgcgacga cttctgatca gcggcgagat
    21001 cgcgcagagt gtccaacgcg tgccgatact gctcgatgtc gcgagcgtct tcgacgtact
    21061 cccctccagt gacgagttcg acgtaaacga gtcctggatc atctgtctcg gtcgggaagt
    21121 caaggaggta gaaggatccg ccatcctgag ccgggttggg agcggcatcg aacggcagga
    21181 cgagcagctc tatctgcggc cgcctggacg cctcgatgag gtgtttcatc tgctcgatca
    21241 tcacgtgacc gtcaccgcgc ttgcggtaga gcacagactc atcaaccacg gcgacaagcc
    21301 gtgcgggctc gttgtcgcga tcaagaatct gctgacggcc cacgcgaacc tcgaccagct
    21361 gggcgacctc ggcctctgac aggttgggat tgccgctgat caccgcgtgc gcatacgcag
    21421 gggtctgcag catcccaggc acggtcctgc agtcaaagct cgcgagctcc gtcgcgccga
    21481 actcgagtcc gagaaacagg tcgaaccact tcggcacgtt gccggaaagg gatgcccacc
    21541 aacgattggc gttcctcgcc gcggccagca gctcccgcat gaatgggatg cggtcgccct
    21601 tgccgtagag gtcgaggaga agttcgaggt ccgacgctgg cggcagcctg tcgttctcga
    21661 tgttgctgat atgcgctatc gatcggccga tgcgcgtggc ggactctgcc tgcttgaggc
    21721 cagcctcatc tcgccatcgc ttgagcgaga ggttgatcat gcgccggaac agcgccgggc
    21781 tgcctgactg cagcgctcgt ggaagtcctg actcgttcac acagccaccc tttcgactcg
    21841 gccgagtcta tagcggagag atcacccgat cggacgtacg atgtcggatt gacgttgtga
    21901 atttcacagc gcaaagttta catcggctgg ttcacacttg cgccagcccc aggagcgccg
    21961 caggcgtaga caccccatcc gcaacctgcg gcgttcctgg cccatcgttt gtgcacctgg
    22021 aggcgttatg tcagcggtgc gttcgactcc cggcgggcgg gctgaacccc cgacccgtcc
    22081 gctcgccggg gttccatccc tgatccgggc atccggttcc tgctcgtgcg gctgcgtggt
    22141 ccccgcctcc cggaccgcgc gcccgagcag tgcggatgcc gtcccggccg gtccgcgcga
    22201 cattcccccg accgccctga ccatgcgggc gcagtcgcgc ggaccggccc tcctcgggac
    22261 atcaccatgg cgggccgcct cgtctggcct gcccaagact ccgacggtcc cgtcatcgac
    22321 ctcgtgcagc gcagtcagcg ccgtgggcga cggcggccat cgacctggag gtcgatcatg
    22381 aactctctct tgaccatccc atggcgaatg cccaccggga acgatctcgc gaccacggtg
    22441 tccgcctacc ggaagctggg ctgggacacg ttccccgatg agcacggttc gatcatggcc
    22501 ggggtcggcg agcgattcga cgtcgctacc ttcccggatg cgctggcacc ggcgttcctc
    22561 agcgagctgc ccgatgcgcc ggtattcgtc gacgcccgga tccaccgctg cacagtgctc
    22621 acgtcggtgg cgtgcgacca agtccgcgat gtcgcccctg atctcgccga ggcgcgggtt
    22681 cgcgcgctgc ctcggcggac gcccgtgatg ctgccggtct tgatggagga cgactgggac
    22741 gggcatcgcc gctggttggt cgcgcccgac gctgcggtgc ttccggggtg ggacgagacg
    22801 atcgccgcga tcgggcgtgc gatcgaggtg gcacgatgac cgccgccacg gcaccgagga
    22861 tgccgctgta cgagcagggt ttgctgcgtg cgttgcggat ggtcgaccgc ggccggattg
    22921 gcgcgttcgg gctcactgct ccgctgggtt tccactccgg cgacgtgcca ccgtcatggc
    22981 tgatcagtgc cttgttcgtg ctgcgtcgtg acgagttggc cgcactgggg cctgccgagt
    23041 ccggggacgg gtggcggccc gcagtgctga cgtcgctggg aaccgctctg ctcgcggcgt
    23101 ggaacaagcg gctcagtgac gccaagccgt acgtcctggc tgtcgggacc gtcaccccgg
    23161 ttctgcacgt cgtcgccacc gaggatcacc tgccccgggt cgccgacacc gacgatggtc
    23221 cgcgctggat cgcgctgtgc cgtgggctga cgcggccgga gcgtgccgat cggacggtcg
    23281 gagtcgtcct gtgtgagcgg tgcgcgctgg aagcccgagg tgcggcgtga gcgcggcgtt
    23341 ggcgcggtcc ctccctctaa ccacggagcc cgagatggac taccccgccg agacggcgtg
    23401 ctggtggggc agcagcccgc actatcgggg ccgagcccac ctgatcgtcg gcggcgcccg
    23461 gtccgcgctg tgcgggatcc tggtcgacga gtccaccggc taccggccct ttggccgcac
    23521 ctgcccggag tgcgcgctcg cctacgtcga ccggttcttc gtcccaacga cccgcggctg
    23581 gccgtcgtga ggggacgatc ccccgcggcg ggcgatcctc gggccgcgca gttgggcgct
    23641 gagctgcgct ccgcacgtct ggcccgaggg tggactcggt cggagatggc ggctcttctg
    23701 ccgttcgacg tcacgttcca gacgttggcc agctatgaac tgggcaaccg gcactgcacg
    23761 gtcatgcgac tgctcgacct gtgcgacagc ctggaggtct cggcctccga ggtggtcggc
    23821 gtcgtgtcct gccacgccgg ggactgcccg gctccgacgg ggatcgtcgt cagttgcgcg
    23881 gtgctggcgc gcacgacgcg accggcgctg catccgttgc ggcgctgggc gaagaccatg
    23941 gtcacgcgcg atcccagccg tgaccgcgtg gtgctgtcgg acgcggcggt ggtgatcgcc
    24001 gccgagctat gtggtctgag tccggccacg atggacgcgc acctgcgtac atgcctgaag
    24061 tactccaccc gatgatggga cgtgactgag tgaactccgt gcaggaccag accgacacca
    24121 gtgtgtccga tccggaccta ctgcgagcgg cgatggtcgc cgagatgcgc cgagaaggcg
    24181 acatccgcac cgacgaggtg gcggcggcgt tcgcggcggt gcctcggcac ctgttcgcac
    24241 cgagcgcgtc ggtcgacgag gcgtaccggc gcgacgacat cgtggagcgc aagtacgacg
    24301 agaacggcct tgtgaccagt tcggtgtcag cgccgtggtt gcaggcgatg atgctggagc
    24361 aggccgaact caagcctggg atgcgggtgc tggagatcgg gtcgggcggc tacaacgccg
    24421 cgttgatcgc ggagttggtc ggcaagtcgg ggcaggtgac gtcggtcgac atcgacaccg
    24481 aggtggtggc gcgggctcgg cgctgcctgg acgcgaccgg ctacgagcgg gtcgaggtcg
    24541 tactcggcga cgccgaacac ggggtggcgg ggcgcgcgcc gttcgatcgg atcatcgtga
    24601 ccgccggggc gtgggacatc ccgcccgcat gggtcgacca gctcgctgac gacggtcgtc
    24661 tggtggtgcc gttgcggatg cgggggctga cccggtcggt ggtgttcgcc cgcgacgcag
    24721 atcggctggt ctccaccggg tacctgctgt gcgggttcgt cgcgatgcag ggcgagggcg
    24781 ccagcgcgga gcggctgatc ctgctgcgcg gcgaggacgt cgcgctgcgg gtcgacggcg
    24841 accatgactt cgacgtcgcc gggctgcgcg agtcgctgtc ggcgccgcgg gcggagcgct
    24901 ggtcgcaggt ggacgtcggc gggttcgagt cgttcgacgg attggacctg tggctggcgg
    24961 gcgccgccga cgacttcgct ctgctggtgg ccaccgacac ggcccgggag tccgggctgg
    25021 tgccgcccgg cacacggttg ggcgccaagg ccatcgtgga cggtgccagt ttcgcctatc
    25081 gcacgtcgcg gccgacatcg gaggagcgca cgacgttcga gttcggcgtg ttcgcccacg
    25141 gccccgacgc cgaccgactc gccgagcagt acgtcgaatt gatccgcacc tgggaccggg
    25201 aacaccggca cggtccgggc gcgcgcatcg aggtcgtccc ggccgaggtg ccactcggtg
    25261 cgcttccggc cgggcgtgtg atcgacaaga ggcacacccg cgtcgtgatc tcctggcccg
    25321 ccgcgtcctg acggcaggcc aggtgtctgt gaaatccctt atctgaaagg aaaatcgcgt
    25381 atgagcacgc agtccgccga gcagttcgac ctggatgtgc ggttcctcga ctccgtgccg
    25441 gtgatcccgg agctgatgac caacaccgac gacaactgcg ggtcgacctg ccagagcgcc
    25501 tgctccaaca gcagctgcta gccagcctat ttcggccggt ggcggggtcc ccgccaccgg
    25561 ccgttccatg tccgaaagga gttcccgatg tatggggtcg tcgatgccgc ggtcgtccgg
    25621 gtggccgctc acccgatcac gaccgacatc ccgccgtggc cgcagctgac cggcccggac
    25681 gcggagaacg tggcggggtg gcgggcgtgg ttggccgcgg tctgggcgat cgagtcgttc
    25741 gccgaggccg tgcgcacggc gagcccgacc ttggcgggcc gggtcgcggc tgtgtgcggt
    25801 gggcaggagt tgcccgctcg gcaggtgcgt cgcgcggtcg tgtcagtgat gcggtacctg
    25861 ctgcgggcca ccacgcgggc gaccccgttc gggctgttcg ccggggtcgc caccgcccgc
    25921 ttcgggcaag tcacgaccgt gcgccgcgta caggacgcga aggtggtgac cagggtggac
    25981 ccggtgtggc tcgcgcaggt ggtggccagg ttggaggcct gtccggcgtt gttggcacgc
    26041 atcgaggtgg tggtgaacga ctcggtccgt gaacgcgacg gacggctggt ggtcgaactt
    26101 cgccccgacc caggcggggt cgccgagcct gccgaggtat cggtgcggct cacccgcgca
    26161 gtgaggatcg tgatgcgcgc tgctcgctcg cccatccggg tcgcggcgat ctccgatctg
    26221 gtgtgcgcgg agttcccgga cacgtcctcg gacgcagtcg atgggctggt tcgggagttg
    26281 gtcgcgcaac ggatactggt gaccgggctg cgcgcgccga tgaccgtgac cgacccgctg
    26341 ggatacctgc tggcgaacct ctgtgccgcg ggtgccgatc gggtcccgga gatcatgccg
    26401 ctggtcgcgg aactgcgggc gatctacacc gaaatgaccg gcgggcggcg ggctcgtgcg
    26461 gcgtcggcga tggccaagat cgcggtcgcg gatcgacccg ttcacgtgga catgcgcgct
    26521 gatctggacc ttgtcctgcc acagatcgtc atccgggaga cggtccacgc cgctcgggtg
    26581 ttgacgcagc tcaccgcgca cccgttcggg cacccgaggt ggcgcgacta ccaccaccgt
    26641 ttcctggaac gctacgggcc gggagcggct gtgcctgtgc tcgatctcgt tgaccccgat
    26701 gtcgggctcg gctatccagc gggctaccgc ggctcgctgt tcgaccgtcc gccacctctc
    26761 ctgtccgacc gcgatgttcg gctactcgcg ctggcccagc actccgcgtt ggcaggcgag
    26821 gtcgaggtca ctctcgatca gagcgcggtc gacgagttga cgtgtggcgt gcccgtggcg
    26881 tggcgcccac acaccgagtt gtcgttccgt ctgcacgcca ccagccggga ggcggtcgac
    26941 cggggtgagt tcgacctcga tgtcgtcggc atgttccgag aagcgggcac aaccatcggc
    27001 cgattcctcg acgtgttcgc cgcagcggag cgcacccgaa tggcaggcgt gttcgaggcg
    27061 ttgccgacct cgacgctcgg cgcggtgcgc gcgcaactgt cgtgcccgcc gctctacacg
    27121 cggaccgaga tcgtctcccg cagccgaacg atgctcgggc acatcctgcc catcggcgag
    27181 catcgcgacc cacaccctgg cctcgtggac ctgagggacc tcgtggtgat cggcgaacca
    27241 caccgcttcg tgctgtggtc gacgaacagg cgacggccgg tggagcccac cgcactcaac
    27301 gcggtcgaag ccaccaactt cacgcacccg ctgcaacggt tcctcgccga ggtcaccacc
    27361 tcccgcgcag cgaccagcgg gccgttcacc tggggcacag cggcaggcgg gctcccgttc
    27421 ctgccgcgac tgcgccacag acgcaccatc ctgtcccccg cgcgatgggt cctgaccgcc
    27481 gctgatctcc cccgcctcga cgcgtcgtcg ggctgctggg ctgacgaact gcagcggtgg
    27541 cgacagcacg cccgcgtgcc gggcacggtg ttcgtcggcg gcggcgatca acggctccgg
    27601 ctcgacctca ccgaacccgc gcaccaggcc ctcctgcgcg acacgatcaa ccgagaccag
    27661 cgggtatccc tgcacgaagc accacccgct gacgcgttcg ggtggctcga cggacatgcc
    27721 cacgagatcg tcgtcccgct cgcctccacc caactgcccg ccgcgccgat ggccgaacct
    27781 gtgcacgtgg tccggcgcgg cgacgaacac ctccccggct ccgacggctg gctgttcgcc
    27841 aagctctacg gccaccccga ccggcacacc gccctgctcg ctcacctccc cgacctactg
    27901 tccacctggg atgcaccgcc ctcgtggtgg ttcctgcctt accgcgatcc cgaccaccac
    27961 ctgcgcctgc gcgtccgcgc cgacgacccg gccacagcag ccagggtcgc ggcctgggca
    28021 cggcacctac gtgaacgcgg gctgatcagc cacctctgtc tcgacaccta cctgccagag
    28081 aaagccaggt tcggcaccgg cccagcggtg gccgccgccg aggcggtgtt cgccgccgac
    28141 tccgctgcgg ccacctccca acgccacacc gacagtcacg cgctcaccgc cgcaagtctc
    28201 gtcgacatcg ccgtgtcctt ccacggcgac gtcgaagccg ggatgcactg gctcatcgac
    28261 aacatcacca ccgacacccc cgtcccgctc ccgcgacacc aactggccca cacactccac
    28321 ctcacccacg aagccgacgc actcccgcca tcaatgccgg cgcgctgggc tgaacggcgc
    28381 cacgcgctcg actcctaccg cgacagcctc gccaccatcg gccgcgagcc gcactgggcg
    28441 ctcgcctccc tgctgcacct gcactgcatc cgcgccaacg ggatcaaccc gaccgccgaa
    28501 cgcctcagcc accgactcgc ccgagccgct gccctcacct ggacccgtcg ccgatgaaca
    28561 caaccgacat cgccgaggtc ctggcccagc gactggccga ccccaccacc acaaccaccg
    28621 ccgacaacac ccaccgcccc gtcccccagt ccctggccaa cggcgccgcc ggaatcgccc
    28681 tgctccacat cgaacgcgcc cgcaccggcc acggctcccc cgccaccgcc cacgcatggc
    28741 tgaccgccgc caccgcccaa ggcgtgcacc gcggcgacca ggcgggcctg ttccacggcg
    28801 cccccgccct cgccttcgcc accaacctcg ccgcccaagc caccggcggc taccagcacg
    28861 cgcactccga cttcgctgcc gcgaccatct ccatcaccac aactcgcctc gccctcgcac
    28921 acgcccgcat cgaccgaggc gacaccccgg cactcgccga gttcgacctc attcgcggcc
    28981 tcaccggcct cggcgcctat cacctcacag cacaccccga ccacccgatc accacagcgg
    29041 tgctggccta cctcgtccaa cttgccgagc cccaccccac ggggttgcca ggctggtgga
    29101 cccacctggc accctacggc cgccgctctc acgactactc ggacggacac ggcaacttcg
    29161 gcgtcgccca cggcatcgcc ggaccactgg ccctgctcgc gatcgccatt cgggagggcg
    29221 tcgtcgtgcg cggccacata gcggccatca accgcatcct cacgtggctg gacacctggc
    29281 agcaacgcac cccaacaggt acctggtggc cgcgcaccat caccaccgac gaactcggca
    29341 caggccgcac ccaaaccacg cggcccggac caccctcctg gtgctacggc actcccggcc
    29401 tcgcccgcgc ccaacaactt gccgccatcg ccaccaacga cccaacccgc cgccacaccg
    29461 ccgagaccgc gctactcgac tgcctcaccg accccgccca agccgaccag atcaccgacg
    29521 caggcctgtg ccacggcgcc gcaggactgc tccacaccac aacccgcatc gcctccgacg
    29581 ccagtgtccc cgaactcacg agtctgctgc ccgacctcac cgcgcggctc atcgaccaac
    29641 tccgacggca accggcgggt accgaactac tcgacggctc cgccggcgcg gccctcgccc
    29701 tgcacagcct caccgcccag cccaccagct gggaccgctg cctactactc gcctgacccg
    29761 gagaaaccgc cgtgcgaccc cagctcccgt ggagccaggc cgtccttcac ctcaccgact
    29821 acacgacagc cgaacacctc gccgtccacc gcctgcggcc cctcatgacc accgccgaac
    29881 acaacaacga catcaccgcc tggtggttca tccgcaaagc accgacctgg cgcatccgat
    29941 ggctccccac acgccccaac ggcgacccgg tcgttcacca cgcgctcgac gaccttcgcg
    30001 acactggcct actcgccggc tggaccatga cgatctacga gcccgaaacc cacgccttcg
    30061 gcggcgaacc cgcaatggac ctcgcccaca ccctcttcca ccacgacagc caccacatcc
    30121 tcgaccacct cgcccgcacc ccagaaccgg accagcgcca cgaactgacc atcctgctct
    30181 gcgccaccct catgcgcggc gccggactgg actggtacga gcagggagac acctgggccc
    30241 gcgtcgccca caaccgccta aacacagatc ccatcagcca cgacaccaca gccatgcgcc
    30301 gcctcctcat cgccgacacc acccccaact cccccaagcc caggaacgcc ctcaaccaga
    30361 tctccggctg gatcagcacc ttctacaccg ccggagaaca cctgggccga ctctcacgga
    30421 ccgggaaact ccacagagga ctccgggcgg tgctcgcgca ccacatcctg ttccactgga
    30481 accgactggg cgtcaactat cgcaaccaac accgcctcgc gaacacagcc acaactacca
    30541 tcctcgatgg gctcacgtcc ccgaagtgcc gctcgcgcag tacttcgcga actcgacgtt
    30601 gaacgacgcc tcgaccaccg cgttgtccac cgccgaccag gctcgtagcg tccaatggcg
    30661 cttccttcgg cgggtacgac tatgccgcct gagtcgaaat aggttccgtt acgacgcgac
    30721 ggttgcgaca tcttccaggg tgagtcgcca acgaggagat ccgcgcacag cgcgacaaca
    30781 tcgggcggct gctcggcgcg atctgcgacc tggaggccga ccaaccagag aacggcatct
    30841 agccatcctc tcccagaaca cctcactcaa gcagcagatc cgccaactcg gtcagaacaa
    30901 ccgccagctc catgagcaac tgcagggcgc acaggacaac aaccgggccc tcgacaacga
    30961 gtcgccgacc tgaagcccag atggctccaa ccccgatcgc ggggacacct ctgaacgttc
    31021 gctgaatcgg tgtccgactc ctcggaacct cagttgccgg tttccaggta cagcgtggcg
    31081 gcgacatctc gtagatgtgg tgccgtcgat ggagctgagc cgccgtcaat tgtccaacgg
    31141 cggcaccttt cgcactccga ccggcagttc gtcagtgccg acgtgggcgg cagcgacgcg
    31201 caggtatgcc agctgcgcgt gctcggcctc tgtgcgcgcc tggtaccagg ccgcgcggac
    31261 tcggccaggc catgcggcga gcgcaggccc ggtgtgcagc agcaccagac atgccagtgc
    31321 cacggcggtg gtcgccgcac cgtccagccg caccgcgatg tggatcaccg caccgtctcc
    31381 agccccgctc cgggttttcc aggttgccaa cttggtgccg gacgcaacaa catcgccgcg
    31441 cgccgttgtc ccttcgaggg cggcccacca gcgtgatttt ccagcaacaa ccagatgcgc
    31501 cgccacgcac gggcctgttc ggcagcggcg tacatgtcca ccccgtccgt acgctgcgct
    31561 tggccgacga gtgtgttcag cgaggcccac acgttgccct tcgccgtggc ggaccggcgc
    31621 cggacgtgca gtgggttggc cagtccggcg aggatgtcgg tggcggcggt cagctgtgtc
    31681 cgtaggtcgc ggatctgcat cgtgccgagt ccggacactg atccagccag gcgtgaccgt
    31741 accgcggata cagccgacgt caggtcgacc tcgtcggcgc gcctgcgccg gacgcgcccg
    31801 tcgggttggc cgaacgcgtt gagcactcgg acgagcaggc cctggatgat ctggtcgcga
    31861 gactcgttgg cgacatcggg atgcggtatg ccgaggatcc tcgcctcgag ttgtgcccgg
    31921 tgcagttcgc tgattcgctg gtagtgctcg ggccagcaat acagcaggtt gagcaaatcc
    31981 ttgtcgctga tccacagccg gtcggtgtcg agcattcgcc tggccgtgtc gacggcctcg
    32041 aagaagcgca accgcgtcac gtagaagtgg gtgagcatca ggacacctga cgcggcgacg
    32101 ctgtcgcggc cgaccacggc aaggcctggc aggggcatcc gcggcaggtc cagtggcacc
    32161 ctcgaaacgg cgctgggtgg actggtgggt ggggtcttgg gcatgacaga actcctgacg
    32221 tgacgggtgg ctgtgagtga tgcgcacatc acgaatcgtg gcggacgtgc cccacgcgct
    32281 cgggggatcc tcaggtcacg ccaacaattc tgatgtcgct cgactgtgaa cagggcgctc
    32341 gccgcaggca cggccgcctg cgtccctgca cctgtgatac gccgaatacc cgccgagcac
    32401 aaggctttcg tccctatggg gttcgtgacc gcccggctac cgtctggatg ggatccgatg
    32461 cggggggtgt tgtattcact gcacgattca tctggtcggc gaacgcgacg ccgccttggc
    32521 ggcagccgtg cgatctgacc tgctgagacg tgccgtgaca gtggagaacg gcaggcggac
    32581 ggtgcgcacg ggccggccgt cgggggaagg agcggccccg cggctgtgca tcagcgccga
    32641 gccggatgac accacggccg acgcggtcga ggacctcgcc gacgaaggcg gccgggtgct
    32701 ggtgatcgca ggcgcgcgcg gctgccgcgc gcggatgtgc tggcggctgc tgtccagcgg
    32761 ggcgtgcgat gtcgtctcct gggctccgca gaacaatccg ggggccgcgg tggtcgcccg
    32821 actcgccaga tgggccgagg tggacgcgga ggtcagctcg gatctggtcc gcggtcagct
    32881 cgtcgggcgc agtgcggcct ggacggcggc attacgtcac gtggtcgagg tcgcgcgttt
    32941 cacccgcacg accctcctcg tgaccggcga gagcggcacc gggaaagaac tcgtcgcgcg
    33001 gttgttccac catctcgacc gccgtcagga caagggggac ctggtcgtac tcgactgcac
    33061 gacagtggtc ccgaccctgt ccggcagcga gttcttcggg cacgaacgcg gcgcgttcac
    33121 cggcgcggcg aacgcacgcg acggcgcgtt cgcggcagcc gacaaaggca cgctgttcct
    33181 cgatgaggtc ggggaactgc ccatgccgct gcaggccgaa ctgttgcggg tggtccagga
    33241 aggcacgttc aagcgggtcg gcggcaatac ctggcatgcc acgaacttcc ggctggtctg
    33301 cgcgacgaat cgggatctgg acgccgagat tcgggcgggg cggttccggc tcgacctgta
    33361 ccaccggctg gccgcgaaca gggtcgcgtt gccgccgctg tgcgagcgca ggggcgacat
    33421 actcgagctg ttcaaccact tcctcgccaa ggagagcggg ggacgcgtcc cgcagctgga
    33481 cccggccgtc tgcgcactgc tcgagcggcg ggactacccg ggcaacgtgc gagacctgcg
    33541 gcagctcgcg gttcgaatcg ccgcccggca tgtcggaccg ggcccgatca ctcccggcga
    33601 cgtgcccgac gaggaacgcc ccatcgacct gcccgccgag ggcgaccgca cgatccgggt
    33661 gctgctggag gaggcggtgg gcgcggccct gaaagcgggc cgtggatacc gagagatccg
    33721 agactcggcc gcggacgccg cggtacggct cgcggtacgt cgctgcgggg acgacctgca
    33781 gcaggccgcg ctacaactgg gcgtcaccga ccgaatggtg cagaaatggc gtgcgcaatc
    33841 acgaaccgac cggtcggagg ctacggcgcg atgtccagat gcacatgcag caccagcggc
    33901 ccgtgccagt tcaggttcgg acgcgctccg gtccttggtt gacccatgaa caccacgttg
    33961 cgaacgccgg tgtgcctgtt gatcgcctca gcgaccgagt agtcgttgta cagcgcgcgc
    34021 caacggacgc cgacgtcggc cgctgcggcg ttcaccgcga gcagcaacgt gatcgcctcc
    34081 gccgggcggt agaacccgcg gccgtccagc gggggcggca ggaacagatc gaccgaataa
    34141 cccctgctgt cgaacgaacc cccaccgtga cctgcgtagt tgcccgcggt cacggtccga
    34201 tggcgtccgc gcagcgcccg caggaaccgg ttggtcagtg cctgcacggg tgtaccggtg
    34261 cccggcaatt cgatcggctc gagggcatcg ccgcccgcag gcttggaggg aggtgcgaag
    34321 tcgacaagtc gtcggcccgc ggtgcctctg gtctggaact ccagccgctc actttgaccg
    34381 aacatccaac cccgtgcgat ctccgcgagc ccgcgccgat caccgtaccg gccatgtgcg
    34441 ccacgaatgg ttcccgcgaa atcgttgtcg aggtaggcga ggtagcgtgc ggcgtccggg
    34501 gcgccagccc gcggattcgc ggccaaggtg cgctcggcgt agcaggcagc gagcgagcga
    34561 gcgaagtccc ggaccgcggc cagtccggcg aaccgcgtgg gctggatgag cgcctcgccg
    34621 cagctgcggg tgtcggtgac ggcgggaacc tccacgcacg gcgggaacac caccggcgag
    34681 acgggcgaac cgggcgatcg cggtgcgacc gggtccggct gtcgtcggga cggttgcggt
    34741 cggcccggcc tcggtgggct tgtcgctccc gcgtcgacca gcgcacgctc ggtcagtggg
    34801 ccgacgatcc cgtcgggcac taggcgcctg cggcgctgaa acgagcgcac ggcacctctg
    34861 gtcagcgggc ccatgatgcc gtcggcggca agcccggcgc tggtcagccc gttgaggctg
    34921 ttctgcaccc accggacata ggcggggaac cgccggtccg cccgaggcga ggccatctca
    34981 cggtgctcct ggtcggtgac cgtgtcgaga gcgcggtcca cgagccgcag ccgaagcgtc
    35041 tgcactgccc gcgccacagg ggtggccttc gccgggttga ccagcgcgcc gcgggccagt
    35101 gcccgatacc acagcagggt ccgcctagtc agccccggcg gaaccaggaa attcgccatg
    35161 cgccagtgcg ctccggccac attgcggccg aggaacgtcc gcagcagcgc cagctgttcg
    35221 gcgctcgggg gtggtgaggc cccgggacct ccgccgccgg gatcggtttc cgcctgcagg
    35281 cctgccgcgg cgaacgggtc gtcgagcagc aacaccgcac cgtggcggtg ccaggttccg
    35341 gctagcgggc gtcggttcgg gcactgtgtc atgggggtga ctccgatcag tctgtgcgac
    35401 cgagccgaac cagccggtcc cacgggtcgg tatcggcagg caatcggcct gcgggtgggt
    35461 gggcgggcag cggggtgccg gtgcgcaccc tcgcgaccag gcgcaacacg ttgccgccga
    35521 gtaccagccg catggcctcc gcggtgaggt cgagcgcgtg caccttggcc aactcgacgc
    35581 cggggtgcag ccacggcccg tccgagccga acagcacctt gtgcgggccc gccctgcgca
    35641 ccgcctccac cagcaggtcg aaccgtcgta ccccggaggt gtcggtgtgc acgttggggt
    35701 gacgtgccag cacgtcgatg aacgcgcgct gggcccgcca gtcgtcggcg aagctgccga
    35761 ggtgcgggat cacgaacgcc acccttgggt actgcccggc gaacatctcg atgggcgcga
    35821 cgtcgcccat cacgtcgtag ataaccggca gccgccaccg gtctgcgacc gcgcagacct
    35881 cccgcgtgag ccgcccgtcg tgccggtggg ccttgatgcc gaggaaccgg tagccgcgga
    35941 ccgcgtggct gaccagctcc gctactcgcc cgcggtcgcg ctccgggtgc acgaacgcga
    36001 acccgacgaa ccggcgcggt ctcgcggcga cgatccgtgc cacctcggcg ttggccaagg
    36061 cgtagtcgga gctgaacggg gcgaacagca cggtgccatc gatgcgggcg gctgatgccc
    36121 ggcgtaggta gtcgcgcagc ggcgccgagg tgtcccacgg gccggtcagc ccgtcgccgg
    36181 ttcccgcgtg gcagtgacag tcgacgaccg ggtagtcagc ccacacggag caccagtccc
    36241 cgatgctcag gccattcggc ccccaccgga ccaccggcac gatccatctc agcaccggag
    36301 tgctcgatcg cgattgcgaa gccgcgcatt ccgagaaccg gcgacgaggc gacgtccagc
    36361 atggcgacac gcccgttcag cgaatcgtgc gcatgtgtac gtccatgcgc ctgcgcagca
    36421 ggaaccccgg cactgtggcg tccacccgtt cggtcaggtc gacgcccgtt gtcgcacggt
    36481 acgcgtgggt gtaccgctgg atctccggcc gccagtagcg tgcccagttg gctgcttgct
    36541 gtgggtcgtt caccacgctc cagttgccgt agcggatgcc tagcagcagc tgctcaccga
    36601 agacacccat atccctggtg tgcgtgacgc tggtgttcgc ccacccctgc aactgcttca
    36661 tggtgtcgac ccggtccatc cactcctcct cgtagggcac catcgcccgt ccgccgagga
    36721 actcgcgcat ctccggccgt gcgagcagcc actccatgat cagcatttcc gcgcgggcgg
    36781 ctgacggaag gtcgccgaac tggttgtgcg cgccctcggc gaggatcagg tgcgtctcgc
    36841 gcagcgcgtt gagcagcggg aacccgtcgg caaggaccgt ggtgtcgtcg tcctccttga
    36901 agaacaggga gcagttgtgc agcagggtgt ggaacgactc gacgaagcgg gaccggctgt
    36961 ccaccgtcgc ctgtcgggaa acggcgcggc cgagcagggt gagtccgtac tcgtggtcgt
    37021 attcgaaggc ccgcctccgt acggtcagcc ggtgcaactc atcctccgcc catccccaga
    37081 acaggttggc gagcggccgg agcggatcca ggtcgaagcg ggccagcggg tcgacaccgt
    37141 ggacggtgcg ccggttctgg aaccgcgcga ggatcgcgtt gatcgcctgc acgagcatgc
    37201 cctcctcgtg ccagtacgac cagatcaact ccatggccag cggtccggtc agccgcgagc
    37261 ggagaatccc gtagcagttg tcggtgatct cgcccgggct cttcagcggg atgtcggaca
    37321 ggcggtccct gatgacgcgc aggtagggca gagtgatcgc gccgtcctcg ccgagtcggt
    37381 cgtagtacag gccgcgcatc gtccgcagat cgtccagcgt gaccggcctc gagcggccgt
    37441 agcggtgcgg ttcctcgccg aggaagcggg tcgcttccag tgacccggac gcgagctcat
    37501 gctccatcag ttcggggtcg aggaacgctg tcggtgtcga acaggcatca ccttcgacaa
    37561 tgccgcactc ctgcatcagg aacgcgtcgg tcgcctgctt gagcacctgg taagcctggg
    37621 tgccggtgaa attcagcacg tgcccggtgc cgttgcggtt gcgcacatcc accgcgcggc
    37681 acatgacgcc gtcgatgaac tgcttgtagt gccggaacgc gatcgcgttc gtgcggttgc
    37741 ggatgatcgt ccagagcacc tgatcggagg tcggggtcac accggtgcgc tgcaggctga
    37801 ccggcacggt gccctccggg ctgaccacgc ccgtcagttg cgcggtgatc tcccacccgt
    37861 cggtctccag gttgtccggg ccgtcatagc gcgcggcacg gaccacgttg ggcaacgcgg
    37921 tgtcaccggc gccacccgtg ccgccgtcga acaggtcgcc gtcctcacct ccgccgatgt
    37981 caccgccgat gtcgcctgtt ggaatcccgg cgtcgcgttc ggaccgcgtg gcgtacacgg
    38041 tgtaggcacc cggggcacca ggcgcgaagt cgatcttcgg tccgcggtca ctgagctgct
    38101 gctcgtcgtc ggaccgcggg ccgacgatcc gccagtcgac ccggtacctc cccgcgtcag
    38161 ccagcttgcc gctgaccagc gcctccaacc gcaccgtggt gccgacctgg accggatcct
    38221 tcgggaatcc cctgagcgtg aacgtcttgc tggacacggg gtgtctcctc atcgcctcgt
    38281 catatcggta atgtcgatgc ccgggcgcag agcacggagg tatccaggct gctgcgcacc
    38341 gcccatcggg ttagctgcgc accgagcagg tggctctcct gctcgggact gatcacgccg
    38401 tccgcccggg cttggccgac tgcggcgaat accagcgcag gcggggcatc gcgcagtgct
    38461 tgtgggacat gtggccatgc ccggaagttc gtttcgagct cggcgcgctg ccgatcgggc
    38521 aggtgcagtg ccgtccccag ggccgcgcca cccaacgcgg gcgggcggtg gtcgagcagt
    38581 gtgtcgatga acgcaggcac gtggccaagc agcgccgcaa ggcgcgatgc gaggccagcc
    38641 ggcgcctggg cgagcggata cagggacgac cacatggcgg ccagccgccg ccactgtggg
    38701 tccgggtaga gcgcgtcgcc catagcgcag ctgagctgca cccgaatcca cggaaccgga
    38761 tggggatcgt caccgctggg acggaacacg aaccagcgtg gcaggctgac caccccgatc
    38821 aggcccagcg tggagccgat cccgagcttg gcaaccgacc agaggtccgc gacgatctcc
    38881 gatatccacc tcgaccagct ccgccacgcc gcaccggcgg ggcccacggc actggcctgc
    38941 gcggcccgca gcgtctggcg cagcgagccg accaggtcga gcagtgcggc cgcctggtga
    39001 ccgacctcgt gcacgagcga ggacgcgatg ccgtgaccga tcatccgttc ccgaggtacc
    39061 cgaatcagcg cgaccgggtt ggacccgccg ccgggtagcc gggtccgcgc cctgcggatg
    39121 gccgcccccg ggccccgagc cagataacag ataaccggcg gcggctcgaa gtagccgccg
    39181 ggaagccgca gtgcatcagt cgccagcagg tccaaaccgg acagccacac accggtctgg
    39241 aactcgctgc gttgggtgat cgcctcggtg aacaggtcga actggttcag gatgtcgttg
    39301 aacgccatcc tgatcagtgc gaagcgctgc tgttgctcgc tcggcgcgac agcccggcca
    39361 gggcctgcca accagcgcag gtactcggtg acctgatcgc gaagcaccgc ccggccgtcg
    39421 agcaggaacc gctcgacggc ggacagcgcg gacggcagcg gggccgccgc cgagaccatc
    39481 gtctcgtgca ggacgaacgg gcgcacccga tccaaccggg tgagcaacgc gcgagcctcc
    39541 tgctcgagga aggcagcagg cgtggcaggt tgggagttca ccgtcgcacc ccggtcacgc
    39601 gccgaggatc acgatcttgc gaccgcgccg gacccaccgc ccggtctgcg cggttccgct
    39661 cgtggcatca gtggcgtcga ggtcggcatc actgtccatg aaggatggtt caatgccgtc
    39721 ggcgccgtcg gcgccgaacc cgtagccgcc ttgccgaggc ccatgtggcg agttccagcg
    39781 gccaggcggg cgacggacca ggccaggggc gtgcctgcgg gccgcggaca gcacggcggc
    39841 gcgaaccaca gcgcgcggtg gcgcaccact tggtgcgcgg gcggcgtttc gagccgcagc
    39901 ggtcgcgaaa cgcacgtagc gccgggccac ctcgagctcg gcctcctgct cgccgagtcc
    39961 ctccaactcc agttcgaaca tcttgcttgc catcgagccg agctgcgagc cgaccatccc
    40021 gccgatgccc ggcagcacca tgttgcccag tgcgcccgcc gccatcggca acgccgcctt
    40081 ggcaacgccc ttcagcgtgc cacccagtgc ccggccgatc ggcgacctga gcatcccgcc
    40141 tgccgccttg gccgcgcccc tgagcagctt gccgaggaac tgttcgagct cctcctcact
    40201 ggcgacctcc agcagctcgt tggccagctc gaactcctgc atctcgccga gcgactccat
    40261 ctcgccgccg aacatctcac cgagggtgtg ctcctggctc tcgagctggc ccatctcccc
    40321 ccactccaag gcttcccact caccgggggt ctcgaagcct tcccactcct gggtctcaaa
    40381 cgcgctcatc cgtcctgctc ctgctcgtcg ggacgcgacc gcctgccgcg tcggctgatc
    40441 actcgatgtg gttcacgatc tggtcgccgt gtcgttatcc gcggccgctg ccgcctgctc
    40501 gcgcaccgcc cgccgcgagg gcagccagcc cgggcgcgtg tcgatgggcg gcgctggaaa
    40561 cggcggcctt ggcgacggtc atgggccgcg cgtcgagtgg tg
//
