LOCUS       NZ_LN850107            20699 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Alloactinosynnema sp. L-07 isolate Alloactinosynnema sp. L-07
            chromosome I.
ACCESSION   NZ_LN850107
VERSION     NZ_LN850107.1
KEYWORDS    RefSeq.
SOURCE      Alloactinosynnema sp. L-07
  ORGANISM  Alloactinosynnema sp. L-07
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2015) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900070365.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:00:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,999
            CDSs (total)                      :: 6,934
            Genes (coding)                    :: 6,831
            CDSs (with protein)               :: 6,831
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 30 of 103
            Pseudo Genes (incomplete)         :: 83 of 103
            Pseudo Genes (internal stop)      :: 1 of 103
            Pseudo Genes (multiple problems)  :: 11 of 103
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:22:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3575145
            Orig. end                         :: 3595844
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN850107.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20699
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="20"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20699
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20699
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10699](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10699
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    complement(43..57)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     gene            complement(188..280)
                     /locus_tag="BN1701_RS38215"
     CDS             complement(188..280)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="BN1701_RS38215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_082859873.1"
                     /transl_table=11
                     /translation="MAVRGACSKNSSGPHLTFPDTAWKAFLTTR"
     misc_feature    complement(343..356)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            350..1576
                     /locus_tag="BN1701_RS15635"
     CDS             350..1576
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="BN1701_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_157368005.1"
                     /transl_table=11
                     /translation="MFSAEVIAEMSDVETLDLLRELERRQAALDAAKVRALAHMARLRP
                     DLDAGGHRFAGAEVGAALTWTPAQAATQVTRAVRLTTLFPTTVDALATGRIDLARAHAL
                     AEITATLSDEHAREVETWILARHEHKTIAGWRQALRAKKDRIDPDGADRRRELRRRERR
                     VDLYVAEDGMAHFDVYDTGERLRAVYLVVDKMARTMRAHGSPETLDTLRADALYDLVVH
                     GGGRGVTVELQVAVPYTVLLGANLGGTLDGYGSVPNITIRELISEHDTHWRRILTDPVG
                     KVLEVSTRRHPGADLTRHIRLRDQTCRFPGCHRPAVSCELDHTIPHSHGGTTSAPNLGC
                     LCLFHHKLKDQPGWRLKQTRPGLFIWTTPTGETHTVDQEPLIHYDDTPAPRQRDTRQLA
                     TVREEPAPF"
     gene            complement(1662..1841)
                     /locus_tag="BN1701_RS15640"
     CDS             complement(1662..1841)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="BN1701_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_054049563.1"
                     /transl_table=11
                     /translation="MAAVWRKSSHSGGGGNDDCVEVAVTELAIGVRDSKNSSGPHLTFP
                     AASWAAFLTPVAPD"
     gene            complement(1854..2684)
                     /locus_tag="BN1701_RS15645"
     CDS             complement(1854..2684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667942.1"
                     /locus_tag="BN1701_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5753 domain-containing protein"
                     /protein_id="WP_054049565.1"
                     /transl_table=11
                     /translation="MSPKSIPPFRRRRLGRRIRELREAARMTLEVAAKQLDMTRFTLAR
                     LEKGENKMDVHIGRSMMDVYDCWDDDLLDQIRKAAPTGWWTKYGIRDRGYIDMETEATT
                     VDTFQVVYVPGLLQTEDYMRAVFRSSRAGWSPDQIENQVAARLVRQRRLTDADFPLRLS
                     VILDEAVLRRQVGGVCAMRAQLGYLVESATLGTVTLRVLPHTAGAHPGMDGAFSLLSFP
                     EEDTEIAYVAYSTGAVHIERATEVREARLLFDQLRSMALSPLESVGFIEQVASD"
     gene            complement(2757..3548)
                     /locus_tag="BN1701_RS15650"
     CDS             complement(2757..3548)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465337.1"
                     /locus_tag="BN1701_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_054055885.1"
                     /transl_table=11
                     /translation="MAARRGPGILIRLLVVVLALVAIVGVGWLVRVVVVPTAGPLADDI
                     PALEIEAAPVEPGSVAPGGLAAPQPQAAGGADPLRAWAERLAGPTGIPARALMAYGNAE
                     LAVRSSSPGCRLSWATLAGIGRIESNHGRYGGAELREDGRLSKPIIGVPLNGSPGVKAI
                     SDTDGGLFDGDAQVDRAVGPMQFIPSTWRRWTSDANLDGVGDPQQIDDAAFAAGRYLCA
                     NGRDMGSAQGWWAGVFSYNNSVPYGQKVFGLADEYARTAAA"
     gene            complement(3657..4145)
                     /locus_tag="BN1701_RS15655"
     CDS             complement(3657..4145)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637527.1"
                     /locus_tag="BN1701_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_054049567.1"
                     /transl_table=11
                     /translation="MLDDPGVDALVRQWTAERAQDAEAVEAHRIASEWLADAPVAPIVP
                     GIPGQRVRGGAARWSTVEGTDPRYLAAMRKRLPEVPEELLSAAAGWWQMVGGVAEAEEW
                     WDAGMSPLDQRALDYRAAGLAPSDLRRRLGPLTVLEHLRRGSAPAWCVARLQRQRGAA"
     misc_feature    complement(4306..4319)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.87"
                     /tool="antismash"
     gene            complement(4370..4531)
                     /locus_tag="BN1701_RS36460"
     CDS             complement(4370..4531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681111.1"
                     /locus_tag="BN1701_RS36460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_172803261.1"
                     /transl_table=11
                     /translation="MDAKKAAILVVVAISLFYVITQPTAAADAVQGIFGWLRDGAEAII
                     TFLKNLFA"
     gene            complement(4850..5980)
                     /locus_tag="BN1701_RS15660"
     CDS             complement(4850..5980)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681110.1"
                     /locus_tag="BN1701_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_054049569.1"
                     /transl_table=11
                     /translation="MGPLAGLKVVELAGLAPAPFACTVLADLGADVVRVDRAKPGFDVL
                     SFPNDPLTRGRRWIGVDMKSPEGLDLVLRLVDEADVLVEGFRPGVAERMGLGPDALLAR
                     NPGLVYGRITGWGQDGPLAPAAGHDINYIAISGALEPIGQAGAKPTVPLNLLGDFGGGG
                     LMLAMGVLAALFERQSSGRGQVVDASMVDGAALLTTSLFGLRNLGLWNKPRGENLLDGG
                     APFYDTYETSDGKYVAVGAIETRFFGELVKVLGLEDVPDHLNPENWPALRDLFGATLRT
                     RTRDEWAKLAEGTDACLSPVLTPEEAPSHPHNVARATFVEVGGITQPAPAPKFSRTVPP
                     VPAPPSQARADTSAVLGELGLSEAEISRLRAAGTVA"
     gene            complement(5999..7141)
                     /locus_tag="BN1701_RS15665"
     CDS             complement(5999..7141)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240107.1"
                     /locus_tag="BN1701_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_054049571.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.4e-34, bitscore:
                     115.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.5e-27, bitscore:
                     93.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.3e-41, bitscore:
                     138.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYRSPWMDEDLDAFRDLAKNFCEKELTPNVERWMENHEVDRDLW
                     RKAGEVGLLCLSIPEEYGGGGGTFAHETVLVEQQARAGDSGWGVLLHNGIVAHYILAYG
                     TEEQKHAWLPKMASGEWVGAIAMTEPGTGSDLQSVKTKAVRDGDEYVVSGSKTFITNGG
                     QADVIIVVAKTDTSKGADGTSLIVVEADRPGFRRGRVLDKIGLKAQDTAELFFDNVRVP
                     ASNLLGSAEGQGFVQLMQQLPQERLIIGVTSVIAMELALETTLAYTKDRQAFGRPVYNF
                     QNTKFKLAEIATEARIGRVFLDDCVAKHLKGELDIPTVAMLKWWTSERAMVAIDECLQL
                     HGGYGYMNEYPIARMWTDQRVQKIYGGTNEIMKEIISRTL"
     misc_feature    complement(7177..7193)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            7255..7866
                     /locus_tag="BN1701_RS15670"
     CDS             7255..7866
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465342.1"
                     /locus_tag="BN1701_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_231949609.1"
                     /transl_table=11
                     /translation="MITRTHRTQQERRAQTREALLDATIATLVELGYARTTVQEICARA
                     GVSRGAQQHHFTTKAELLTSALEHLFDRLIAEVTQAAGALPPGRERLIKGIDLLWEAYS
                     GALSTAAVELWVAARTDEELRQTLLPVDRALGHATLEVLRAAAEGEPQKTASDAETVLL
                     LTINLVRGLALDAMIGGDPRRRARLLDEWKAMILDRYLRT"
     gene            complement(7912..8355)
                     /locus_tag="BN1701_RS15675"
     CDS             complement(7912..8355)
                     /GO_process="GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337744.1"
                     /locus_tag="BN1701_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="co-chaperone YbbN"
                     /protein_id="WP_054049573.1"
                     /transl_table=11
                     /translation="MSTWKRLLCGAIGVLALVTGPAVGAAQAAPTAPAAENVIDVTAAN
                     HAEVLNISKTKLVILDFGATWCPPCQKMKPVLAKLAKEYNGRILVGMVDADRSRDLMRQ
                     YSVRYLPTLVPLRNGKELPSSRLVGFPGERQLKAWIDKQLAKG"
     misc_feature    complement(8340..8355)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.79"
                     /tool="antismash"
     gene            complement(8403..8753)
                     /locus_tag="BN1701_RS15680"
     CDS             complement(8403..8753)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634598.1"
                     /locus_tag="BN1701_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_054049575.1"
                     /transl_table=11
                     /translation="MLPLISRDELRSAMTGGTVIVVDTMPVSYYEKEHLPGARNIPGFP
                     YENAAEFTDRFAPSVVPDKAATIVVYCSNIPCRNSEFVGRRLLELGYADVRKYREGIED
                     WVSAGLPTDTGA"
     gene            complement(8843..9811)
                     /locus_tag="BN1701_RS15685"
     CDS             complement(8843..9811)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337742.1"
                     /locus_tag="BN1701_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_054049577.1"
                     /transl_table=11
                     /translation="MRLQIRHLRVICAIADSGSLNRAAGILGLGQPALSHQLRRIERLV
                     GGELFHRDQNGVRATGLGSIVLRRAKAIVLTFDEVERDFQRRETDDGPLRVGWNDSVLA
                     VPLLDSLRDLRPDAEVRSRGDGSRARLLAQAAHGGIDLALVTACGTRGHTTPASVRTLT
                     LVAEPSFVALPSGHPLAERGEVALADLARENWIVPSCGDGCRVTFREMCLAHGFDAKIV
                     HDVDEVTARENLVIGGHGVGLVQPTRPQREGMVCRQLAGSPLFVRHMIAWREGGPCADY
                     AQEIANRVTADYWRMAQGVPHYRYWLTRNANVEVGGSPAEG"
     gene            10001..10699
                     /locus_tag="BN1701_RS15690"
     CDS             10001..10699
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF028025.4"
                     /locus_tag="BN1701_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_231949611.1"
                     /sec_met_domain="CDPS (E-value: 9.2e-74, bitscore: 246.4,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLRPLPLTQHCASPLAEAEHVCIGVSPFNSYFTTERIADLARWA
                     VSSFASFHFFVPDAPSAYTLEAIGYTPRDAARKAQRQGNYTRNKIHRALAQCAIDPGPV
                     ILDSAALEVNPMYSKLRTEAHHRFTSDPGFAKHCLSATSWVLEKRLRDAEPTHAQSMHA
                     VRYFLAEMPMFVNTVEIAGVSSSVFAYHQRVPFLEKLFARELSWQPHPAQGFVVVEPVV
                     AEQVAAESAL"
     gene            10696..12006
                     /locus_tag="BN1701_RS15695"
     CDS             10696..12006
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013675201.1"
                     /locus_tag="BN1701_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytosine permease"
                     /protein_id="WP_054049579.1"
                     /transl_table=11
                     /translation="MTVTQKPSGHDDYSLSRVPPEQRVSWITVAVQRFGQVSSFHQFLL
                     GAVLGFGMTFWEAVIAITVGSVMLEIITIMMGIAGTKEGLSTALLTRWTGFGRSGSAMV
                     GLLISLSLAGWFGVQNDVFAHGLHALMGGPPVWVWALAGGALVTAIVVFGFHAMAWTAY
                     LTVPAFLALAGYSIIDALGEHSLADLVAAAPPGPAMSLAQGTTLVAGAFIMGAVMTPDM
                     TRFNGSPADVVKQTLVSVTLGQYVIGLVGVLLAHAAKSSDVVGIITSSSGVLGTLILVT
                     AILKINDWNLYSSSLGLINTVEVLFSRTLDRVTATCLLGAIGTVLSAIGILTHFTTFLM
                     WIGVITPPVAGVVIAEYFLVKRWRAELEASRATGDLPATCPNWVPLGLVCWAGGAAVGF
                     LVPIGIPTINSVIAALVMYVALSKVTTNRAISRAVGR"
     gene            12015..12962
                     /locus_tag="BN1701_RS15700"
     CDS             12015..12962
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028563.1"
                     /locus_tag="BN1701_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_054049581.1"
                     /transl_table=11
                     /translation="MHLDVHHLRVVRAVAESGSLSRAAAALGVTQPAASAQLKRLEQLL
                     GYQLFERRGGIVVPTAMGDLLLRRITSVLPQMDRLLEDIGLANGADLPPSTARVGAVCS
                     AVVAHLASAISSVWPEIDETTIVHDDDSDGLLALLEEGRAECAMVKDYPGYELTLPRAV
                     DMAVVAVEPTFVMLPEHHPLACNAEIELTDLRDANWVLAGNGTSAVFTEFFTRTCADAG
                     FVPDITHMVSSQPMAQMVVRSGAVGLVQPCCEGHAGVAIRPLRGEVLRRRHVLAWRGDT
                     FVAERQEKLVAALSEAYWSEAERSPAYRRYLSCN"
     gene            complement(13014..14465)
                     /locus_tag="BN1701_RS15705"
     CDS             complement(13014..14465)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632027.1"
                     /locus_tag="BN1701_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_054049586.1"
                     /transl_table=11
                     /translation="MTPRIRRLVPPSVGAIALVAMLTGGGPPAAAAESTIGTDGYVHVS
                     PMGTVLGADPYYPKDGNGGYDVGDYNLAIEYLPSSTSIRAKATITATATQDLSRFNLDL
                     CGLSVYSVKVDGVGATHARVGDHELVVTPRTMLAAGAAFTVEIVYGGSPRPLGTARGLV
                     GWQRGYESAVAVGMPRSAMTWFPVNNTEVDKATLHVALTVPNGWQAVSNGTRVSDTPIS
                     GYRHTVTWAEETAVAPSAVMAAMGRRWQVDTATLPDGRSVYNAYATWALDKRALGNKLP
                     EVIEFLSGVLGDYPQSAAGGMFLDRPATTHPAQTRPVYGVYAGMSDLVYATAYQWWGDG
                     VTTKMWKDTQLTESFARYAVWLWDAEKNGVDLDQRYLDQVTAAKADARFWAPKLTDPGA
                     RAEYTPTAKGVLMVHALRKTVGDELFFQMYSGFPAINQQSNQGWYDFGLYAEAVAERDL
                     SGFFGAWWNGTVIPADEFLFPGEGR"
     gene            14652..15845
                     /locus_tag="BN1701_RS15710"
     CDS             14652..15845
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337737.1"
                     /locus_tag="BN1701_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_054049588.1"
                     /transl_table=11
                     /translation="MRHYRNPPASALLALATTVFLGCLAEVLPAGLLLDMSADLGVTPS
                     MTGQLVTVYAITTAATAIPLTAATVRVPRRALLLGLIVGFLVTNAVIAVAPDYETVFVA
                     RIVSGALTGVMWSLVAGYAMRLARPVVRGRALAVAMAGTPIGFAVGVPAGTFLGEVAGW
                     RWAFATMALITIPLLMWVVIALPRLPGEVSRPTPARAASRLPGMAALLAIVVAFSLGHN
                     VIYTYIGPVLADAGNGGLLGVTLLAFGAATIAGQCAVGAALDRHPRRVLALCSGLSAAG
                     VVLMELSAGEPVLMVAAAAVWGTAFGGAPTAFQAATALIAGHTADAAQSLTIAAWNGAV
                     AIGALVGGLLLRVGPSTLPWTAACLVALPLIILAYALPPAAMDRSADTVQLRLNSHR"
     gene            complement(16100..16810)
                     /locus_tag="BN1701_RS38220"
     CDS             complement(16100..16810)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024826.4"
                     /locus_tag="BN1701_RS38220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SidA/IucD/PvdA family monooxygenase"
                     /protein_id="WP_157368006.1"
                     /transl_table=11
                     /translation="MAPPAPSATEHNARPGSGIRRFLERQPDFGLYRGMLIDDATMRVF
                     LKDLVTQRHRAVDPALPAGCAPLAGRGRGESTGPMAEAVVTGAAIVREYRLFVARRSRP
                     QSVAGFWELPGAEVAPGQDEQSALSDRFTSEFSISLRCVDRILSDRALTAWPTDDEDYD
                     SAILRIWRCQLPSESTLDLDLGDPRPNMYVYDETRWVPIDELDQVSPWRDADRITASEI
                     ADHYLADDWWQAAD"
     gene            16971..19238
                     /locus_tag="BN1701_RS37320"
     CDS             16971..19238
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="BN1701_RS37320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_157368007.1"
                     /transl_table=11
                     /translation="MSGGSAGAGRVTASYLVLTLALLGVAGWCLLSRALAPSDGATVNV
                     GDTAIVATGSGSVLVKQVRAGPLRVGDEILTIDHIRPASHILPGGPAAMAGDRLAYQLV
                     RDGQVVEVEVVVRAYPVFRDLLDGWPTILVVGVLGATSVLIFLARPGEPAARAALVAAA
                     LAVVTTTGATFFPLQPLDLVAGEQFWRWFIGEAGFVLLWSAMLHFSLAFPTVTVRRFRQ
                     WVALGYLAGPLLYAVVCAIALATADSPLDRLAVLGSPAVPALFVFPVLILAVLARQYRA
                     CADPAARRRLRWLATTLGTGAVGYLAVWAVPTMVAGAPLLPDRFHTLAFLPVPIAVGLA
                     VLRHRALDIEVVLSRSLVYGALSAGVVGTYIAVVASLSLLFPPMDQMWQQAVAAAAVAI
                     LVQPLRGWLQGLVNRRLFGFADDPYRVVSRLASRLENTHEPGAMLPGIVETVANALRLP
                     FVAIEIQAKGGPEVAASTGTPSGDRHELPLTFQGERVGTLVVGGRAVLRARDRLALADV
                     ARHAGTAVYTARLTMDLRRSRDRLVRAREQERRRILHELHDGVGPTLAAIALGLDASRR
                     GVGADTATGVLLARMRAELQDAITEIRRLAAGLRPPVLDQIGLVPALREYAGALASRTA
                     KLDGTDEGVTIMLEVPTVMPRLPSSIDVAAYRIVCEALTNVTRHAYARSCAVRLWVDDD
                     LHIEVVDDGIGLPRHTFGGVGLASMRERAAELGGDCLVAAEAEGGTRVLATLPLPKEVA
                     TQ"
     gene            19399..20055
                     /locus_tag="BN1701_RS15725"
     CDS             19399..20055
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804079.1"
                     /locus_tag="BN1701_RS15725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_054049594.1"
                     /transl_table=11
                     /translation="MTEARPRVLVVDDHPLFRFGLCTVLAAEPSVDLVGEAATGAEAIA
                     AARELAPDVVVMDVHLPDMTGIDAARAIVGERLGTGVLVLTMFNDSESVFAAMRAGARG
                     YLLKGSGQDEIVRAVHAVGRGEAIFGPDIATRVLGFFNAGPEVPGPVFPELTVREREVL
                     ALIADGVSNSGIATRLSLSPKTVRNHVSSIFTKLHVADRAQAIVRARKAGLGDGH"
ORIGIN
        1 ttggagcacg tagccgaggt tctggaaggt tccattggtc gactcgaacc gctcccactg
       61 ccaccaggcc aggccgaggc acgcggcgag cgacagcaca cagaccccga tgaccagggc
      121 cttacgcgca tatccggaac cgtcacccac gcgccgatgg tagaccgggg tagctgagag
      181 accgccgtca cctggtggtg aggaaggcct tccaggcggt atcggggaag gtgaggtggg
      241 gaccggacga gttcttggag cacgcgcccc gaaccgccat cgttccacga tcgggtgatc
      301 agtgcttgac ctgcgggaat ctgccgggtt cgacggtaag atcgaacaca tgttcagtgc
      361 tgaggtgatc gcggaaatga gcgacgtcga aacgctggat ctgctgcggg agctggagcg
      421 caggcaggcc gccctcgacg ccgcgaaagt ccgcgcgctg gcccacatgg cccggctgcg
      481 accggacctc gacgccggtg gccaccgctt cgcaggcgcc gaagtcggcg cggcgttgac
      541 ctggacccca gcccaagcgg ccacccaggt aacccgcgcg gttcgcctga ccaccctgtt
      601 cccgaccaca gtggacgcct tggccacggg ccggatcgac ctggcccgcg cgcacgcgct
      661 ggccgagatc acggcgaccc tgtccgacga gcacgcccgc gaggtggaga cgtggattct
      721 cgcccgccac gagcacaaga ccatcgccgg atggcggcag gccctgcggg cgaagaaaga
      781 ccggatcgac cccgacggag ccgaccgccg ccgcgaacta cgacgcaggg aacggcgggt
      841 cgatctgtat gtcgccgagg acggcatggc gcacttcgat gtgtacgaca ccggagaacg
      901 gctgcgcgcg gtgtatctgg tggtggacaa gatggcgcgc acgatgcgcg cccacggctc
      961 gccggagaca ctcgacaccc tgcgcgccga cgccctgtat gacctggtcg tccatggcgg
     1021 cggacgcggt gtgaccgtcg agttgcaggt cgccgtgccc tacacggtgt tgctgggggc
     1081 gaacctgggc ggcaccctcg acggatacgg cagcgtcccg aacatcacca tccgggagct
     1141 gatcagcgaa cacgacaccc actggcggcg catcctcacc gaccccgtcg ggaaagtcct
     1201 cgaagtcagc acccgccgcc accccggcgc cgacctcacc cgccacatca gactccgcga
     1261 ccaaacctgc cgcttccccg gatgccaccg accagcggtg tcctgcgaac tcgaccacac
     1321 catcccgcac agccacggcg gcaccaccag cgcacccaac ctcggctgcc tgtgcttgtt
     1381 ccaccacaaa ctcaaagacc aacccggctg gcgactcaaa caaacccgac caggactatt
     1441 catctggacc acacccaccg gagagacaca cacagtcgac caagaaccac tcatccacta
     1501 cgacgacaca cccgcaccaa gacaacgcga cacgcggcaa ctcgccaccg tgagggagga
     1561 acccgcgccg ttctagaccg ttcgacaggt cgaaggctgg gtgccgaccg ctgccggcgg
     1621 agaccggtca agggcgcgca aggctgggtg cggccagccc ttcagtcggg cgcgacgggg
     1681 gttaggaatg ccgcccagga agccgcagga aaggtgaggt ggggaccgga cgagttcttg
     1741 gagtcccgaa ccccgatggc gagctcggtg acggcgacct cgacacagtc gtcgttgccc
     1801 ccacccccgc tgtggctgct cttccgccag accgctgcca tgtggccagc ccttcagtcg
     1861 gatgcgacct gttcgatgaa acccactgat tcgagcgggc tcaacgccat cgatcgaagt
     1921 tgatcgaaca gcagtctagc ctcgcgcacc tctgtcgctc gctcgatatg gaccgcgcca
     1981 gtcgagtagg cgacgtaggc gatctcggtg tcctcctcgg gaaagctgag caggctgaac
     2041 gccccgtcca tccccgggtg ggcgcctgcg gtgtgtggca gaacccgcaa ggtgacggtc
     2101 cccaatgtcg cggattcgac caggtacccg agttgggctc tcatcgcgca caccccgccg
     2161 acctgtcgcc gcaacaccgc ctcgtccaag atcactgaca gccgcagagg gaagtcagcg
     2221 tcggtgagcc gccgctggcg aaccaaacgg gccgcgactt gattctcgat ctggtccggc
     2281 gaccatcccg cgcgactcga tcggaagacc gcccgcatgt agtcctcggt ttgcagcaga
     2341 cctggcacgt acacgacctg gaatgtgtcg accgtggtgg cttcggtctc catgtcgatg
     2401 tagccgcgat ctcggatccc gtacttcgtc caccagccgg tcggcgccgc cttgcggatc
     2461 tggtccagga gatcgtcgtc ccagcagtcg tagacatcca tcatcgatct gccgatgtgc
     2521 acgtccatct tgttctcgcc cttctccagg cgagcgaggg tgaaccgggt catgtccagc
     2581 tgcttcgcgg cgacttccaa cgtcatccgg gcggcctcgc gcaactctcg gatgcggcgg
     2641 ccgagtctgc ggcggcggaa cggcggtatg gacttgggtg acaccgacta cctcccgtgt
     2701 gcgaccggtc acccaatgat ccagggtgca cagtgcacat cgggattcac accgaactac
     2761 gccgccgccg tccgcgcgta ctcgtcggcg aggccgaaga ccttctggcc gtacggcacc
     2821 gaattgttat acgagaaaac gcccgcccac caaccttgcg ccgaccccat gtcccgtccg
     2881 ttggcgcaca ggtaccggcc agcggcaaag gcggcgtcgt ctatctgctg aggatcgccg
     2941 acgccgtcga ggttggcgtc ggaggtccag cggcgccagg tcgacgggat gaactgcatg
     3001 gggccgaccg cccggtcgac ctgggcgtcg ccgtcgaaga ggccgccgtc ggtgtcgctg
     3061 atggccttga cgcccggcga gccgttcaag ggcacgccga tgatcggctt ggacagacga
     3121 ccgtcctcgc ggagttcggc gccgccgtag cggccgtggt tggactcgat gcggccgata
     3181 cccgccaggg tggcccacga gagcctgcac cccggcgacg acgagcgcac cgccagctcc
     3241 gcgttcccgt acgccatgag cgcgcgggcc gggattccgg tgggcccggc tagccgttct
     3301 gcccaggccc gcagcgggtc agcgcccccg gcagcctgcg gctggggggc ggcgagcccg
     3361 ccaggggcca ccgaacctgg ttcgaccgga gccgcctcga tctccagagc cgggatgtcg
     3421 tcggcgagtg gtccggcggt cggcacgacc acgacccgga ccagccaccc cacacccacg
     3481 atcgcgacca gggcgagcac caccacgaga agcctgatga ggatgcccgg accacgccgg
     3541 gccgccatca cgtccgtgtc cgccaccgtg ctccagcctg ggtcgccaac gctgccactg
     3601 acagcatcaa cgaactgggc acttcggcgt tactcgaagt ggctcacgcc accggctcag
     3661 gccgctccgc gctgtcgctg cagcctagcc acacaccacg cgggggcact gccccggcgc
     3721 aggtgttcca gcacggtcag gggaccgagc ctgcggcgga ggtccgacgg cgccagtccg
     3781 gccgcgcggt agtcgagggc gcgctggtcc agcgggctca tgcccgcgtc ccaccactcc
     3841 tcggcctcgg ccacgccgcc gaccatctgc caccagcccg ccgcggcgga gagcagttcc
     3901 tccggcacct ctggcagccg cttgcgcatg gccgcgaggt agcgcggatc ggtgccttcc
     3961 accgtcgacc agcgcgccgc accgccgcgg acccgctggc cgggtattcc aggcacgatc
     4021 ggcgccacgg gagcgtcggc gagccattcc gatgcgatgc ggtgcgcctc caccgcttcg
     4081 gcgtcctggg cacgctcggc ggtccactga cgaaccagag catctacccc ggggtcgtcg
     4141 agcattctgc ctcctggagg tctcatgatc actcgatggc ccaaaccgta gggggcagca
     4201 ccgacagatc gccagaccca aagccccaga acttcgccaa cctggccttc cagggggcag
     4261 atccacccgg acggtccaat ttggatcttt ttccaccgaa gatcaacacg gagggtgacc
     4321 accctccggg cggacttcac ctcagtgtta cttgccggta agttcccggt caggcaaaga
     4381 ggttcttgag gaacgtgatg atcgcttccg cgccgtcccg cagccagccg aagatcccct
     4441 gcaccgcgtc ggcggcggcc gtcggctggg tgatgacgta gaacaggctg atcgcgacca
     4501 ccacgaggat cgctgccttc ttcgcatcca tcggctcact ccgtccgctc cgcccggcct
     4561 gcgggctcac ccaacccatg atcccccaag atgacgccaa agagggtctt tttcccgcgt
     4621 ttggcggcac gctgggtgag aacatcgctc ggaccgacac tctcactgtt cgatgatcac
     4681 tctagagggc tagggcgacc atcactccag gagacacagt atgaccctcg gtctcgatcg
     4741 ggtgagctgc cccggcctgg ccgcgtcctg ttcattgggg tgaaacattc actccgcaga
     4801 ggggtgaacg cccgcgagcc gcccgttcgg acaggcggct cgcggcgact caggcgaccg
     4861 tgcccgccgc tcgcaggcgg ctgatctccg cttcgctcag tcccagctca cccagaacgg
     4921 ccgacgtgtc ggcacgggcc tggctcggtg gggccgggac cggcgggacc gtgcggctga
     4981 acttcggcgc gggcgcgggc tgcgtgatac cgccgacctc cacgaaagtg gcgcgggcga
     5041 cgttgtgcgg gtggctgggc gcctcctcgg gcgtgagcac cggcgacagg cacgcgtcgg
     5101 tcccctcggc gagcttggcc cactcgtccc gggtgcgggt gcgcagcgtg gcgccgaaca
     5161 ggtcgcgcag cgcgggccag ttctccggat tcaggtggtc gggcacgtcc tccagcccca
     5221 acaccttcac cagctcgccg aagaaccgcg tctcgatggc gccgacggcg acgtacttgc
     5281 cgtcggaggt ctcgtaggtg tcgtagaacg gggcgccgcc gtcgagcagg ttctccccgc
     5341 gcggcttgtt ccacaggcct aggttcctca acccgaacag gctcgtggtg agcagcgcgg
     5401 caccgtccac catggacgcg tcgaccacct ggccgcgccc ggaggactgc cgctcgaaca
     5461 gggccgccag cacgcccatg gccagcatca gcccgccgcc gccgaagtcg cccagcaggt
     5521 tgagcgggac ggtcggcttg gcgcccgcct ggccgatcgg ctccagcgca ccggagatgg
     5581 cgatgtagtt gatgtcgtgg cccgccgccg gggccagcgg gccgtcctgg ccccaaccgg
     5641 tgatccggcc gtagaccagg ccggggttgc gcgccagcag cgcgtccggg cccagtccca
     5701 tccgctcggc gacacccggc cgaaagccct cgacgagcac gtcggcctcg tcgaccagcc
     5761 gcaggaccaa gtcaagccct tccggcgact tcatgtcgac gccgatccag cgcctgccgc
     5821 gggtgagcgg gtcattgggg aacgagagca cgtcgaagcc aggcttggcc cggtcgaccc
     5881 gcacgacgtc cgcgccgagg tcggcgagga cggtgcaggc gaacggggcc ggggccaggc
     5941 ccgccagctc gacgactttc agaccggcga ggggtcccat agatcattcc ttcgagagtc
     6001 agagcgtgcg ggagatgatt tccttcatga tctcgttggt gccgccatag atcttctgca
     6061 cgcgctggtc cgtccacatg cgagcgatcg ggtactcgtt catgtagccg tagccgccgt
     6121 gcaactgcag gcactcgtcg atggcgacca tcgcgcgctc gctggtccac cacttgagca
     6181 tcgccacggt cgggatgtcg agctcgccct tgaggtgctt ggcgacgcag tcgtcgagga
     6241 acacccggcc gatgcgggcc tcggtggcga tctcggcgag cttgaacttg gtgttctgga
     6301 agttgtagac cggcctgccg aacgcctggc ggtccttggt gtaggccagg gtggtctcca
     6361 gcgccagctc catcgcgatc accgacgtga cgccgatgat cagccgctcc tgcggcagct
     6421 gctgcatgag ctggacgaag ccctgcccct cggccgaccc gagcaggttc gacgccggga
     6481 cgcggacgtt gtcgaagaac agttcggcgg tgtcctgggc cttgagcccg atcttgtcca
     6541 gcacccggcc gcggcggaaa ccggggcggt cggcctcgac cacgatcagc gaggtgccgt
     6601 cggcgccctt ggacgtgtcg gtcttagcca ccacgatgat cacgtcggcc tggccgccgt
     6661 tggtgatgaa ggtcttggag ccgctcacga cgtactcgtc accgtcgcgc acggccttgg
     6721 tcttcacgct ctgcaggtcc gaacccgtgc ccggctcggt catcgcgatg gcgccgaccc
     6781 actcgccgga ggccatcttc ggcagccacg cgtgcttctg ctcctcggtc ccgtaggcga
     6841 ggatgtagtg ggcgacgatg ccgttgtgca gcagcacgcc ccagccgctg tccccggccc
     6901 gcgcctgctg ctcgaccagc acggtctcgt gggcgaaggt gccaccgccg ccgccgtatt
     6961 cctcggggat cgacagacac agcaggccga cctcgcccgc cttgcgccac aggtcgcggt
     7021 cgacctcgtg gttctccatc caccgctcga cgttcggcgt gagctccttc tcgcagaagt
     7081 tcttcgcgag gtcacggaag gcgtcgaggt cttcatccat ccacggcgag cggtacgaca
     7141 tggcccctcc agctggggtc aggcaaacaa tccggcatgc atgtaagtta caaggcgaag
     7201 gtacctgcac gacggactgt ccgtaaagtg ccctggacat cacgaggagg acacgtgatc
     7261 acgcgcaccc accgcacgca gcaggaacgc cgcgcgcaga caagggaagc cctgctcgac
     7321 gcgacgatcg cgaccctggt cgaactgggc tacgcgcgga ccacggtcca ggagatctgc
     7381 gcgcgggccg gggtgtcccg gggcgcgcag cagcatcact tcaccacgaa ggccgaactg
     7441 ctgacctcgg cgctggagca cctgttcgac cgcttgatcg cggaggtgac gcaggccgct
     7501 ggggcactgc cgcccggccg cgaacggctg atcaagggca tcgacctgct gtgggaggcg
     7561 tactccggcg cgctgtcgac cgcggcggtg gaactgtggg tcgcggcccg cacggacgag
     7621 gaactgcggc agaccctgct cccggtcgac cgcgccctgg gccacgcgac gctggaggtg
     7681 ctgcgggcgg ccgcggaggg cgagccccag aaaacggcct ccgacgcgga gaccgtcctg
     7741 ctcttgacca tcaacctcgt gcgcggcctc gccctcgacg ccatgatcgg cggcgacccg
     7801 cgacggcgtg ctcggctgct cgacgagtgg aaggccatga tcctggaccg ctacctgcgg
     7861 acatgagaaa gcggggtccg gagagaagct ccggaccccg ccactgcgag atcagccctt
     7921 cgcgagctgc ttgtcgatcc acgccttgag ctgacgctca cccgggaaac cgaccagacg
     7981 cgacgacggc agttccttgc cgttgcgcag cgggaccagg gtgggcaggt agcggacgct
     8041 gtactggcgc atcaggtccc ggctgcggtc ggcgtcgacc atgccgacca ggatgcggcc
     8101 gttgtactcc ttggcgagct tcgcgaggac cggcttcatc ttctggcacg gcgggcacca
     8161 ggtggcgccg aagtccagga tcaccagctt ggtcttcgag atgttcagga cctcagcgtg
     8221 gttcgccgcg gtcacatcga tgacgttctc agccgccggg gcggtggggg cggcctgagc
     8281 cgcgccgacg gcggggccgg tgaccagggc gagcacgccg atggcgccgc aaagtagacg
     8341 tttccaagtg gacactgtga actccttctg tgcagggatt tctcgatgcc ccgagtgggg
     8401 cgtcacgcgc cggtgtcggt cggcagtccg gccgacaccc agtcctcgat gccttcccgg
     8461 tacttgcgca cgtcggcgta gcccagttcg agcagccgcc tgccgacgaa ctcactgttg
     8521 cggcagggaa tgttcgagca gtagacgacg atcgtcgcgg ctttgtccgg gacgacggac
     8581 ggagcgaacc ggtcggtgaa ctcggcggcg ttctcatagg gaaatccggg gatgttgcgg
     8641 gccccgggca ggtgttcctt ctcgtagtac gagactggca tcgtgtcgac cacgattact
     8701 gttccccccg tcatggcgga gcgcagttcg tctcggctga tcaacggcaa catggcaacc
     8761 ctttcggaca ggtgatcgac accaattcat cgtcgggtcg cgtggcaccg aacctctaat
     8821 gccgcctgtc catgtcggac cgttatccct ccgccgggga gccgccgacc tcgacgttgg
     8881 cgtttcgggt cagccaatac cggtaatggg gaacgccttg tgccatgcgc cagtagtccg
     8941 cggtcacccg gttggcgatc tcctgggcgt agtccgcgca cgggccgcct tcgcgccacg
     9001 cgatcatgtg ccggacgaac agcggcgacc cggccagctg cctgcacacc atgccctccc
     9061 gctgcggccg ggtcggctgg accaggccga ccccgtgccc gccgatcacc aggttctctc
     9121 tcgcggtcac ctcgtcgacg tcgtggacga tcttggcgtc gaagccgtgc gccaggcaca
     9181 tctcacggaa ggtcacccgg cagccgtcac cgcagctcgg gacgatccag ttctcccgcg
     9241 ccaggtcggc gagcgcgacc tcgccccgct cggcgagcgg gtgcccggag ggcagcgcga
     9301 caaaggacgg ctcggccacc agggtcagcg tgcgcacgga cgcgggcgtc gtgtgcccgc
     9361 gggtgccgca cgcggtcacc agagccaggt cgattccgcc gtgggccgcc tgcgccagta
     9421 gccgcgcgcg cgacccatcc ccacgcgagc ggacctccgc gtccggccgc aggtcccgca
     9481 gcgaatcgag cagcggaacc gcgaggacac tgtcgttcca cccgacccgc agcgggccgt
     9541 cgtcggtctc gcggcgctgg aagtcgcgct ccacctcgtc gaacgtgagc actatcgcct
     9601 tggcgcggcg cagcacgatc gacccgagcc cggtggcccg caccccgttc tggtcgcggt
     9661 ggaacagctc cccacccacc agccgctcga tccggcgcaa ctggtggctc agcgcgggct
     9721 gaccgaggcc gagaatgccc gccgcccggt tgaggctccc ggagtcggcg atcgcgcaga
     9781 tcacccgtag atgtcgaatt tgcaaccgca tacctcggta taccgctacc agcacccatt
     9841 cccgaatact tgccagttcc caattaattc ccaattgcct acgcaactca taatccgatg
     9901 acaacggaca aaggcaatac ccgaccccct ggacgcgggt catagtcggc gctacctccg
     9961 agctccctgc ctcggatgcc ttcgatcacc cccaggagtc atggtgctgc gaccactccc
    10021 gctgacccag cattgcgcca gtccactagc cgaagccgaa cacgtatgca tcggagtcag
    10081 tccgttcaac agttatttca caaccgaacg gatcgccgat ctcgcccgct gggcggtgtc
    10141 gtcattcgcg agcttccatt tcttcgtgcc cgacgcgccg tcggcctaca ccctcgaagc
    10201 gatcgggtac accccgcgcg acgccgcgcg taaggcacag cgtcaaggca actacacccg
    10261 caacaagatc caccgtgcgc tggcgcagtg cgccatcgac cccggcccgg tgatcctcga
    10321 ctcggccgcg ctggaggtga acccgatgta ctccaagctg cggaccgagg cgcaccaccg
    10381 gttcacctcc gaccccggct tcgccaagca ttgcctgtcg gctacgtcgt gggtgctgga
    10441 gaagcggctg cgcgacgcgg agcccaccca cgcccagtcg atgcacgcgg tgcgctactt
    10501 ccttgccgag atgccgatgt tcgtcaacac cgtcgagatc gcgggcgtgt ccagctcggt
    10561 gttcgcctac caccagcgcg ttccgttcct ggagaagctc ttcgcgcgcg agctgtcctg
    10621 gcagccgcac ccggcgcagg gcttcgtcgt cgtcgagccg gtcgtcgccg aacaggtcgc
    10681 cgcggagagt gcgctgtgac tgttacgcag aagccttccg gtcacgacga ctactccttg
    10741 tcccgggtcc caccggagca gcgcgtctcg tggatcaccg tcgccgtgca gcggttcggg
    10801 caggtgtcgt cgttccacca gttcctgctc ggcgccgtgc tcggtttcgg catgacgttc
    10861 tgggaagcgg tcatcgccat caccgtcggc tcggtgatgc tggagatcat caccatcatg
    10921 atggggatcg cgggcaccaa agaaggtctg tccacggcgc tgctgaccag gtggaccggg
    10981 ttcggccgca gcgggtcggc catggtcggg ctgctgatct cgctgagcct cgcgggctgg
    11041 ttcggggtgc agaacgacgt gttcgcccac ggcctgcacg cgctgatggg cgggccgccg
    11101 gtgtgggtgt gggcgctggc aggcggcgcg ctggtcacgg cgatcgtggt gttcggcttt
    11161 cacgcgatgg cgtggacggc ctatctcacg gtgcccgcct tcctcgcgct ggccgggtac
    11221 tcgatcatcg acgcgctcgg tgagcactcg ctggccgacc tggtcgcggc ggccccgccc
    11281 gggcccgcga tgtcgctggc gcagggcacc accctggtgg cgggggcgtt catcatgggc
    11341 gcggtcatga ccccggacat gaccaggttc aacgggtcgc ccgccgacgt ggtgaagcag
    11401 acgctggtca gcgtgaccct cggccagtac gtgatcggcc tggtgggggt gctgctcgca
    11461 cacgcggcca agagctccga tgtggtcggc atcatcacct cgtcgtccgg ggtgctcggc
    11521 acgctgatcc tggtcacggc catcctcaag atcaacgact ggaacctgta ctcgtcgtcg
    11581 ctcgggttga tcaacaccgt cgaggtgctg ttctcccgga cgctggaccg cgtcaccgcc
    11641 acgtgcctgc tcggcgcgat cggcacggtg ctgtccgcga tcggcatcct cacccacttc
    11701 accacgttcc tgatgtggat cggggtgatc acacccccgg tcgccggtgt ggtgatcgcc
    11761 gagtatttcc tggtcaagcg gtggcgcgcg gaactcgaag cctcccgcgc cacgggcgat
    11821 cttcccgcca cttgcccgaa ctgggtaccc ttgggacttg tctgctgggc gggcggcgcc
    11881 gcggtcggct tccttgtgcc gatcgggatt cccacgatca actctgtgat cgcggccttg
    11941 gtgatgtacg tggcgctgag caaggtgacc accaaccgcg cgatatcccg agccgtcggg
    12001 aggtaggaca cttcatgcat ctggatgttc accacctacg tgtggtgcga gcggtcgcgg
    12061 aatccgggag tctctcccgg gccgcggccg cgctcggcgt cacccagccc gcggcgagcg
    12121 cacagctcaa gcggctggag caactgctgg gctaccaact gttcgagcgg cgcggcggca
    12181 tcgtggtccc caccgcgatg ggagacttgc tgctgcgccg catcacctcg gtgctaccgc
    12241 agatggaccg gctgctggag gacatcggcc tggccaacgg cgcggacctc ccgccgagca
    12301 ccgcgcgcgt cggcgcggtg tgcagcgcgg tcgtggcgca cctggcctcg gccatctcca
    12361 gcgtctggcc cgagatcgac gagaccacga tcgtccacga cgacgacagc gacggactgc
    12421 tggccctact ggaggagggc agagcggagt gcgcgatggt caaggattac ccgggctatg
    12481 agctcacact cccccgcgcc gtcgacatgg ccgtcgtcgc ggtcgagccg actttcgtga
    12541 tgctgccgga acaccaccca ctggcctgca acgccgagat cgagctgacc gacctgcgcg
    12601 acgcgaactg ggtgctggcg ggcaacggca cgtccgcggt gttcaccgag ttcttcaccc
    12661 ggacctgcgc cgacgcgggc ttcgtccccg acatcaccca tatggtgagc tcccagccga
    12721 tggcgcagat ggtggtgcgc tcgggcgcgg tgggcctcgt ccagccgtgc tgcgagggcc
    12781 acgcgggcgt cgcgatacga ccgctgcgtg gggaagtcct gcgccgcagg cacgtgctgg
    12841 cctggcgcgg cgacaccttc gtcgccgaac ggcaggagaa actggtcgcg gccctgagcg
    12901 aggcgtactg gtcggaggcc gaacgcagcc ccgcctaccg cagatatctg tcctgcaact
    12961 gacaatgtcg ggtcaacggg tcccaacgga cccgttgacc cgacattgtg tgcttatcga
    13021 ccttcgccgg ggaacaggaa ctcgtccgcc gggatcaccg tgccgttcca ccacgcgccg
    13081 aagaagccgc tcaggtctcg ttcagccacc gcctccgcgt agaggccgaa gtcataccag
    13141 ccctggttgc tctgctggtt gatcgccggg aatccgctgt acatctggaa gaacagctcg
    13201 tcaccgaccg tcttgcgcag cgcgtgcacc atcagcacgc ccttggcggt gggcgtgtac
    13261 tcggcacgcg cgccggggtc ggtgagcttg ggggcccaga accgcgcgtc ggctttcgcc
    13321 gcggtcacct ggtccaggta gcgctggtcg aggtcgacgc cgttcttctc cgcgtcccac
    13381 agccacaccg cgtaccgcgc gaaggactcc gtcagctgcg tgtccttcca catcttcgtg
    13441 gtcacgccgt cgccccacca ctggtatgcc gtggcgtaga cgaggtcgga catcccggcg
    13501 tacacgccgt agaccgggcg ggtctgcgcc gggtgcgtgg tggccgggcg gtccaggaac
    13561 atgccgcccg cggcggactg cgggtagtcg ccgagaacgc cggagaggaa ctcgatcacc
    13621 tcgggcagct tgttcccgag cgcgcgcttg tccagcgccc acgtcgcgta tgcgttgtag
    13681 acgctgcggc cgtcgggcag cgtggcggtg tcgacctgcc agcggcgacc catggccgcc
    13741 atcaccgcac tcggggcgac cgcggtttcc tcggcccagg tgacggtgtg ccggtagccg
    13801 ctgatgggcg tatcggagac gcgcgtgccg ttggacaccg cctgccatcc gttgggcacg
    13861 gtcagcgcga cgtgcagggt ggccttgtcg acctcggtgt tgttgaccgg gaaccacgtc
    13921 atcgccgagc gcggcatgcc aacggcgaca gcggattcgt agccgcgctg ccagccgacc
    13981 agtcccctgg ccgtgccgag cggccgcggc gagccgccgt agacgatctc gaccgtgaac
    14041 gccgctcccg ccgcgagcat ggtcctgggg gtcacgacga gttcgtggtc accaaccctg
    14101 gcgtgggtgg cgccgacacc gtcgaccttc accgagtaga cggagagccc gcacaggtcc
    14161 aggttgaacc ggctgaggtc ctgggtcgcc gtggcggtga tggtcgcctt ggcccggata
    14221 ctggtggaag agggcaggta ctcgatggcg aggttgtagt cgccgacgtc gtagccgccg
    14281 ttgccgtcct tggggtagta gggatcggca ccgagcacgg tccccatggg cgagacatgg
    14341 acatagccgt cggtgccgat cgtggactcc gcggccgccg cgggcgggcc gccgccggtc
    14401 agcatggcga ccagcgcgat cgcgccgacc gacggcggca caagccgcct gatcctgggt
    14461 gtcatcgatg atgcctttct agtgcagggt tacggacgcg acgaggcgtc ccgccggtca
    14521 tcctgcgagc gggtgtcggc ttccgggcag tgccaccggg tgatgccgcg gcgttattcc
    14581 cgacacgaat aacgcggcga catccgccaa cgggactatc cgcgcggcgc tgcgtcgcgc
    14641 atgttcgatc tgtgcgccac taccggaatc cacccgcctc ggctctgctt gccttggcca
    14701 ccacggtgtt tctcggctgc ctcgccgagg tgcttccggc cgggctgctg ctcgacatgt
    14761 ccgccgatct cggggtgacg ccgtcgatga ccggccaact ggtaacggtg tacgcgatca
    14821 ccacggccgc cacggccatc ccgctgaccg cggccacggt ccgggtaccg cgccgggcgc
    14881 tgctgctggg gttgatcgtg gggttcctcg tgaccaacgc ggtgatcgcg gtggcgccgg
    14941 actacgagac cgtgttcgtc gcccggatcg tgtccggcgc gctgaccggg gtgatgtggt
    15001 cgctggtcgc gggctacgcg atgcggctgg cccgacccgt ggtccgcggc cgggcgctcg
    15061 ccgtggcgat ggcgggcacc ccgatcggat tcgccgtcgg cgtcccggcg ggcacctttc
    15121 tcggcgaggt ggcggggtgg cgctgggcgt tcgcgacgat ggcgctgatc acgattccct
    15181 tgctgatgtg ggtggtcatc gctttgcccc ggctgccggg ggaggtcagc cgccccaccc
    15241 ccgcccgggc cgcgtcgcgg ctgcccggga tggccgcgct gctggcgatc gtggtggcgt
    15301 tctccttggg gcacaacgtg atctacacct acatcggccc ggtgctcgcc gacgcgggca
    15361 acggcggcct gctcggtgtc accctgctgg cgttcggcgc cgccaccatc gcgggccagt
    15421 gcgcggtcgg cgcggcactg gaccgccacc cgcgccgggt cctggcgctg tgttcgggtc
    15481 tgtcggccgc aggcgtcgtg ctgatggagc tgagcgcggg tgagccggtg ctgatggtgg
    15541 ccgccgccgc ggtgtggggc acggcgttcg gcggcgcccc gaccgcgttc caggccgcca
    15601 ccgcgctcat cgcgggccac acggccgacg cggcccagtc cctcacgatc gccgcctgga
    15661 acggcgcggt cgccatcggc gcactcgtcg gcggcctact gctgcgagtc ggccccagca
    15721 ccctgccctg gacagcggcc tgcctggtcg cgctccccct gatcatcctc gcctacgccc
    15781 tgccccctgc ggccatggac cgatcagcag acacggtgca actcaggctc aactctcacc
    15841 gctgatcacc gccaccggac acgtgaccca cgacgcagcc gccacccaag gggcaccgtg
    15901 acgcaggacg accacggtga ccgccatccg caagattcgg acagagggtg acccagccta
    15961 aaattccggg gaggcggact agtgatcgca ggggccgacc cggccctcgc tcgggtcggc
    16021 gcctgctaca taaggaagag gggggaatcc tcgtttagtg acgttcgctt ttgctaacac
    16081 ttctctaaag gccgcgtttt cagtccgcgg cctgccacca gtcgtcggcc aggtagtggt
    16141 cggcgatctc cgacgcggtg atgcgatcgg cgtcgcgcca ggggctgacc tggtccaact
    16201 cgtcgatcgg gacccatcgg gtctcgtcgt agacgtacat gttgggacgc ggatcaccca
    16261 ggtccaggtc cagtgtcgac tcgctgggca gctggcagcg ccagatccgc aggatcgccg
    16321 agtcgtagtc ctcgtcgtcg gtcggccacg cggtcagtgc ccggtcgctc aggatccggt
    16381 cgacgcagcg cagcgagatg ctgaactcgc tggtgaaccg gtccgacagc gcgctctgct
    16441 cgtcctgtcc cggcgcgacc tcggcgccgg ggagttccca gaagcccgcg actgactgcg
    16501 gacgggacct gcgcgcgacg aacagccggt attcgcgcac gatcgccgcg cccgtcacca
    16561 ccgcctcggc catgggtcca gtggactcgc cgcgaccgcg tccggcgagc ggtgcgcagc
    16621 cggccggaag ggcgggatcg actgcccgat ggcgctgcgt caccaggtcc ttgaggaaga
    16681 cccgcatggt ggcgtcgtcg atgagcatgc cccggtacag gccgaaatcg ggttggcgtt
    16741 ccaggaagcg ccgtatcccg ctgcccggtc gcgcgttgtg ttcagtggcg ctcggcgccg
    16801 ggggcgcgat tcgtcatgcc cgcacgacac tgtgtcgagt ggactgctcc ggtcgccgca
    16861 acacgttccg cagccaatcc gagcgtccgt tcacccggac aggtgacggg ggtaggtgcg
    16921 tccaggcgac acgtctgggt ttggggctac tcctgcggga tgatccagtg gtgtccggtg
    16981 gctcggcggg cgcggggcgg gtgaccgcgt cgtacctagt gctcacgctc gcactcctcg
    17041 gggtggccgg gtggtgcctg ctgtcccgcg cgctcgcgcc cagcgatggc gcgacggtca
    17101 acgtgggcga caccgccatc gtcgcgaccg gttccggctc tgtgctggtc aagcaggtgc
    17161 gggcgggccc gttgcgggtc ggcgacgaga tcctgaccat cgatcacatc cggcccgcca
    17221 gtcacattct gcccggcggt ccggcggcga tggcgggcga ccggctggcc taccagctcg
    17281 tgcgcgacgg ccaagtcgtc gaagtcgagg tcgtcgtccg ggcctacccg gtgttccgcg
    17341 acctgctcga cggctggccg acgatcctgg tcgtcggcgt cctcggggcg acctcggtgc
    17401 tgatcttcct ggcccggccg ggcgagcccg ccgcccgcgc cgccctggtg gccgcggcac
    17461 tggcggtcgt caccacgaca ggggcgacgt tcttcccgct gcagccgctg gacctggtcg
    17521 cgggcgagca gttctggcgg tggttcatcg gtgaggccgg gttcgttttg ctctggtcgg
    17581 cgatgctgca cttctccctc gcgttcccca ccgtcaccgt ccgccggttc cgacagtggg
    17641 tggcgctggg gtacttggcc gggccgctgc tttacgccgt ggtctgcgcg atcgcgctgg
    17701 ccaccgctga ctcacccctg gaccggctcg ccgtcctggg ctcgcccgcg gtgcccgcgc
    17761 tgttcgtctt ccccgtgctg atcctcgcgg tgctcgcccg ccagtaccgc gcctgcgccg
    17821 acccggccgc gcggcgccga ctgcggtggc tggccacgac cctgggcacc ggcgcggtcg
    17881 ggtacctggc ggtgtgggcg gtgccaacca tggtggcggg cgctcccctg ctgccggacc
    17941 ggttccacac gctggccttc ctgccggtgc cgatcgcggt cggcctggcg gtgctgcggc
    18001 accgggcgct cgacatcgag gtcgtgctca gccggtcgct ggtctacggc gcgctgagcg
    18061 cgggggtggt cggcacctac atcgcggtgg tcgcgagcct gtcgctgctg ttcccaccga
    18121 tggaccagat gtggcagcag gcggtggccg cggcggcggt cgcgatcctg gtccagccgt
    18181 tgcgcgggtg gctgcagggc ctggtcaacc ggcggctgtt cggcttcgcc gacgacccgt
    18241 accgggtggt ctcgcggctg gcgtcgcggc tggagaacac ccacgagccg ggggcgatgc
    18301 tgccggggat cgtggagacg gtggccaacg cgctgcggct gccgttcgtg gccatcgaga
    18361 tccaggccaa gggcggcccg gaggtcgccg cgagcaccgg caccccgtcg ggcgaccggc
    18421 acgaactgcc gctgaccttc cagggcgaac gcgttggcac cctggtcgtg ggcggtcgcg
    18481 cggtcctgcg cgcccgcgac cggctcgcgc tggccgatgt cgcccggcac gcggggacgg
    18541 cggtctacac cgcgcggctg accatggacc tgcgccgcag ccgcgaccgg ctggtccgcg
    18601 cgcgtgagca ggagcgaaga cggatcctgc acgagctgca cgacggcgtc ggcccgaccc
    18661 tcgccgcgat cgcgctggga ctggacgcga gcaggcgcgg cgtcggcgcc gacaccgcga
    18721 ccggcgtcct gctggccagg atgcgcgccg agctgcagga cgcgatcacc gagatccgca
    18781 ggctcgccgc cgggctgcgg ccgccggtgc tcgaccagat cggcctcgtc ccggcgctgc
    18841 gcgagtacgc gggcgcgctg gccagccgca ccgccaagct cgacggcacc gacgagggcg
    18901 tcacgatcat gttggaggtg ccgacggtga tgccccggct gccgtcgtcg atcgacgtgg
    18961 cggcctaccg gatcgtgtgc gaggcgctca ccaacgtcac ccgacacgcg tacgcgagat
    19021 cgtgcgcggt gcggctgtgg gtggacgatg atctccacat cgaggtggtc gacgacggga
    19081 tcggcctgcc ccggcacact ttcggcggcg tcggcctggc gtccatgcgc gagcgcgccg
    19141 ccgaactcgg cggcgactgc ctggtcgcgg ccgaggccga gggcggcacc cgggtgctgg
    19201 cgaccctgcc gctgcccaag gaggtcgcca cccagtgatc tgctcagtga tcagctcagt
    19261 gatcgaccca cattgaccgg atcccgcgaa cacccgccga aggaagccac cactcagtga
    19321 tcagctcagt gatcagctca gtgatcgacc cacgatgacc ggatcccgcg aacacccgct
    19381 gaaggaggcc accactccat gaccgaggca cgcccgcggg tgctggtcgt cgacgaccac
    19441 ccgctgttcc gcttcggtct gtgcacggtg ctggccgccg aacccagcgt cgacctggtc
    19501 ggcgaggccg ccaccggagc cgaggccatc gccgcggccc gcgagttggc ccccgatgtc
    19561 gtggtgatgg acgtccacct gcccgacatg accggcatcg acgccgcccg cgccatcgtc
    19621 ggcgaacgcc tcggcaccgg cgtgctggtg ctgaccatgt tcaacgacag cgagtccgtc
    19681 ttcgccgcga tgcgcgcggg tgcccgcggc tacctgctca agggctccgg ccaggacgag
    19741 atcgtgcggg ccgtgcacgc ggtcggccgc ggcgaggcca tcttcggccc ggacatcgcc
    19801 acccgcgtcc ttggcttctt caacgcgggc cccgaggtgc ccggcccggt cttcccggag
    19861 ctgacggtcc gcgagcgcga ggtgcttgcc ctgatcgccg acggtgtcag caactccggc
    19921 atcgctaccc ggctctcgct gagccccaag acggtccgca accacgtgtc gagcatcttc
    19981 accaaacttc acgtcgccga ccgcgcccag gccatcgtcc gcgcccgaaa ggcgggcctg
    20041 ggcgacggcc attaggacgc gcccgaggtc acggttcgtg cccggtcggg cacaatcggg
    20101 acatgggtcc catgcgtccg ggacgcacga aggggcaagg tggactctcc gggatccttt
    20161 gaggcgaagg tgggtttgtg atgctggacc agagcaggac acccgtgatc gtgcgtgcga
    20221 cggacccgat cctgcagaac ggtgtccata tggcattgcg gacccggccg gaggtctggc
    20281 tggtcgacga ggaggacgcc accgccgagg cggtggccct ggtcgtgacg gaccggttcg
    20341 acgaccgggc gaatcacctg ctcaagacgt tgcagtgccg gggtttcgcc agagtcgtcc
    20401 tcgtcgcggg cgaactggag gacagcgaga tcctcaccgc cgtggagggc ggggtctgcg
    20461 cggtcgcgcg acgagcggac accacgcctg acgtcctggt ccgcctcgtc aaggccgcct
    20521 cagcgggcga gggcgcgctg ccccccgacc tgctgggccg actgctgaac cgcgtctccc
    20581 gcctccagcg acacgtcctg gagccgcgcg ggctgcacct ggccgggatc accaaccggg
    20641 agaccgaagt cctgcgcctg gtcgcatccg gactgtccac aaaggaaatc gccgacaaa
//
