LOCUS       NZ_LN850107            25154 bp    DNA     linear   CON 13-AUG-2024
DEFINITION  Alloactinosynnema sp. L-07 isolate Alloactinosynnema sp. L-07
            chromosome I.
ACCESSION   NZ_LN850107
VERSION     NZ_LN850107.1
KEYWORDS    RefSeq.
SOURCE      Alloactinosynnema sp. L-07
  ORGANISM  Alloactinosynnema sp. L-07
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae.
REFERENCE   1
  AUTHORS   Ramaraj,Thiru.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2015) National Center for Genome Resources (NCGR),
            National Center for Genome Resources (NCGR), 2935 Rodeo Park Drive
            East, Santa Fe, New Mexico, 87505, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900070365.1-RS_2024_08_13
            Annotation Date                   :: 08/13/2024 03:00:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,999
            CDSs (total)                      :: 6,934
            Genes (coding)                    :: 6,831
            CDSs (with protein)               :: 6,831
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 30 of 103
            Pseudo Genes (incomplete)         :: 83 of 103
            Pseudo Genes (internal stop)      :: 1 of 103
            Pseudo Genes (multiple problems)  :: 11 of 103
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:22:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2787223
            Orig. end                         :: 2812377
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LN850107.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25154
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="16"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25154
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25154
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15154](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15154
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    493..506
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            complement(504..1307)
                     /locus_tag="BN1701_RS12380"
     CDS             complement(504..1307)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_197672085.1"
                     /transl_table=11
                     /translation="MASDALEGPVPASSGRGQPILDLLDKAIGLQTPLVRKNIARARQR
                     NPEATPADVVRTLERMYVSALASTGAAVGGAAAAPAVGTGIALALSAGEAFSSLELSTL
                     FVLSVAEVHGVQLDEIERRRTLVMGVLLGKSGSTTIGKVAERTGQHWGRQLISKVPTAA
                     LRQINSVLGRNFITKYGTKQGIIVLGRVAPFGIGAVIGGGANATVAALAVKAARRAFGP
                     APLSWPETSPEPTPESPHETPPGVVPGIVLEPAPESNPESRPQSG"
     misc_feature    1588..1602
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(1934..2122)
                     /locus_tag="BN1701_RS34260"
     CDS             complement(1934..2122)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="BN1701_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_082859817.1"
                     /transl_table=11
                     /translation="MSNDARWRTSSFTSDGESCVEVALAVTSAGIRDTKHRAGGTLTVD
                     RESWKLLIDVIIKSPSS"
     gene            complement(2146..3066)
                     /locus_tag="BN1701_RS12390"
     CDS             complement(2146..3066)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="BN1701_RS12390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_231949583.1"
                     /transl_table=11
                     /translation="MTILGRDRVGLEDSVPTVWPKGDMVAAERLPTALGFLVGNELRVA
                     RDQARIKQSTAADFLGITAGGLAHLESGRNRQQPDVVRALLGHYGVPQPQIDRIARLAG
                     RSDADDWWASNADVVPDWLRTLIGLEGLASSSFAYAPMVVAGLAQTRGYARALLTDNLR
                     VPLVDADRVVDVRTDRQRHLWRDENPLRLHCVLEEAVLHRRIGGSDVFREQLQHLLDLS
                     TKPNVTLQVIPFDVPVHDGLDGKFTLLDFTEARSIGYSEGPEGARSVQEPGQVAAYHLR
                     AERIAERALPVHDTRDLIARYMAAL"
     misc_feature    3195..3204
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    3326..3337
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            3831..4184
                     /locus_tag="BN1701_RS12395"
     CDS             3831..4184
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054048453.1"
                     /transl_table=11
                     /translation="MALIAAARVAKTRAELSPAQRTSPWVPILVITDPWLECWLKWDGR
                     ATTDNQDTVLILNTTTLPGLNKVDVADSVVLDAYLDAFTGSLALRGYLVQTSWSKQDRA
                     TQQRVWRLRRKRG"
     gene            4187..>4921
                     /locus_tag="BN1701_RS37255"
                     /pseudo=""
     CDS             4187..>4921
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222898.1"
                     /locus_tag="BN1701_RS37255"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSTTLIEFPEFEDGRLASLVRAGTVSAYGSLYERHVGAARNLARQ
                     LTRSPAEADDLVSEAFAKVLDTLRQGRGPDSAFRAYLLTALRHTAYDKTRRDKKVELSD
                     DVSQVSGVNPDQVAVPFSDTAVAGLERSLAARAFAMLPERWQAVLWHTEIEGQNPAQVA
                     PILGLTPNGVSALAYRAREGLRQAYLQVHLAENSSDRCRATADRLGAWVRGGLSKRETA
                     QVELHLDDCERCRALSAELADTN"
     misc_feature    complement(5135..5144)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            5425..5766
                     /locus_tag="BN1701_RS37260"
     CDS             5425..5766
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS37260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_067520674.1"
                     /transl_table=11
                     /translation="MSRARRLPWIALLSRLRWQRDRDLWTVRCRDHEGRHTLVRVQIRA
                     EGVVLNASRPGALAFTPLAVGRLRAALRDAVVAHAVFAGSTTKDIDYDRDLDHDLDRSA
                     IGGTDAHAA"
     gene            5750..6172
                     /locus_tag="BN1701_RS12410"
     CDS             5750..6172
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054048455.1"
                     /transl_table=11
                     /translation="MPTRHDLTRALLEYRQHGWDAFTDEHGNIMIGVGEHFDALTFPEP
                     LAAAVAEAVSTAPLFLDARTRRCTLLTAIACGPLELPPSLADARVRALPRRTPLLLPLT
                     DQGGDRSWLTRPISPALPPWDTAVTAIRRAATGWFR"
     gene            6169..6666
                     /locus_tag="BN1701_RS12415"
     CDS             6169..6666
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054048457.1"
                     /transl_table=11
                     /translation="MTTALRPSTPLYEPGLLRALRMVERDQVGAYGLTTPLRTRTDEAA
                     PAWLISALFVLRRDDLVCLDPPRGADLWRSATLTALGRDVLAAWTQDRPAPVRPFQAVG
                     SVTAILHYIATEDGRPRTLATEDGPRWIALCRAWTHPARVSHGSGLVRCARCAAHLVPG
                     AP"
     gene            6699..6932
                     /locus_tag="BN1701_RS12420"
     CDS             6699..6932
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157367938.1"
                     /transl_table=11
                     /translation="MNHHHAEPVWRLSWGSSPFYRGRAHLVAPGWPRALCGTVAEATDG
                     KPAPLVCPECAIVFADTAIARMLADRGGWERW"
     gene            6929..7438
                     /locus_tag="BN1701_RS12425"
     CDS             6929..7438
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157367939.1"
                     /transl_table=11
                     /translation="MTTTHGDRRIRLLGKLLHPARDARDWWRLELIAPLPVGIDHTTLG
                     TYEQGTRHRTVARLFELCDTLGVRASEILAAIENDADNATENDSEAQVGPARFDGVTVD
                     GATVDLVAMSVSHPSSLRPLRLWAEHRHVRLTPAAITVLAGLRGMSPPVTRGRLHRRLT
                     IDARTV"
     misc_feature    7400..7402
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7454..7472
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.01"
                     /tool="antismash"
     gene            7468..8223
                     /locus_tag="BN1701_RS12430"
     CDS             7468..8223
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="BN1701_RS12430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_054048463.1"
                     /transl_table=11
                     /translation="MLDKITLDPPRPVPYKKSEHLCARIVGVALRQAVKERGLTYAEMS
                     QRVGVSISSISRVVGGTTNVRLEDIVAVLAVCGVTGERRDRILGMAKRRGHDSDALLLS
                     YGTEHGVDTAALDDLASLATSVTVVASTAHAIATSRPLGNTRYTFLVTAFALAAMPDDQ
                     RADLATLTRVPTVCLRVLDHGPIGESFELLTFEDRTTAVAVRLRTSHLIFDRGDTVLAY
                     RRHAKALTTRALTPQQSRRLITQRATTPE"
     gene            8425..9666
                     /gene="fxlM"
                     /locus_tag="BN1701_RS12435"
     CDS             8425..9666
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024585.1"
                     /locus_tag="BN1701_RS12435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_054048466.1"
                     /sec_met_domain="PCMT (E-value: 1.7e-40, bitscore: 137.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLRDDAVGRDTPGPASTRIDVLRAAMVDELRRMGAIVTERVAD
                     AVLAVPRHVFAPVGEPAERVYAPTTAIVTKRNGQGAAISSLSEAHIQATMLEQARIEPG
                     MRVLEIGTGGYNASLIAELVGESGQVTSVDIDSDIVSSARGCLAEAGYERVRVVLADAE
                     HGVPDRAPFDRVIVTAGAWDIPPAWIAQLTDRGRIVLPLRLRGLTRSVAFERDGDHLVS
                     LSYRLCGFVPMQGAGAHVERTVPLDGNEVGIRVDGAHELDTDALRESLFGPRVERWSGV
                     VFDQVDGMDFFVATTSPGFGLLTATSAAIKRGLVGPSAIRGVPTIVRGAGFAYRMKRPI
                     EGTDDFETGVLAHGPNAEDLARELVDLLRVWDRDHRHGAGARIEVHPAATPAAGLGDGL
                     VVDKIHTRIVISWP"
     misc_feature    complement(9715..9732)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.5"
                     /tool="antismash"
     gene            9748..9909
                     /locus_tag="BN1701_RS34270"
     CDS             9748..9909
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024584.1"
                     /locus_tag="BN1701_RS34270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_231949584.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 4.9e-15, bitscore:
                     53.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIQMDHTPTATADLDWDLDITIVESGGVVDDLLRLTDDGCGATC
                     ESACNSCP"
     gene            10001..13093
                     /locus_tag="BN1701_RS12440"
     CDS             10001..13093
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024583.1"
                     /locus_tag="BN1701_RS12440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_197672086.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.4e-199,
                     bitscore: 661.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.4e-13,
                     bitscore: 49.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.7e-33, bitscore:
                     113.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHVVDDAVLLRASAYQPTVMPWPDLADTSIEGIEQWRAWLGQVW
                     ASTEFAAAVEAASPALARRVRQIRDGQPRPEREVRRAVLAVARYLLRAQGRSTPFGLFA
                     GIAPCTFGDGPVVRVGDDHRVTTRVDTTWLATVITRLETDPVLRQRLVVVAHNVAFTRD
                     GSLVIAYRQADGGGGEPVDLSIRCLDVVARVMTSARDPIVLGDLAATLAIDFPNQPRSA
                     IDRVLDTLVAQGVLRTELRPPMTSTDPLGHVIATLTRAESDTPADTRELVDALRAIHTD
                     LATHDQSSVPALNHTLRAATEAAMAAVSGTERPLAPDLLLDSDLLLPETIAREAAAAAA
                     ALVRLTPEPFGPPNWQTYHGQFLERFGLNAVVPVTDLVNPDTGLGFPSGYRDSLQPPPA
                     GRAMSDRDSALLGLAQKAAMEQEHEIVLDDEMITELAVDDLRTASVQPHTQLRVRVHAP
                     TLDALLRGDFELVVTGVSRSAGLSAGRFLDPFAPEDRARMLRAYQGLPTITENALPVQL
                     SCPPLYPRAENVARTPRVLPHVLSLAEHPPRHADTHLVPIDDLAVTADARRLHLMSMSR
                     RRAVEPLLFSAVELVKHSHPLVRFLTEISTARAAACTAFSWGAASRLPFLPRLRYQRTI
                     LSPARWVLTATDLPSPSAPWQDWAKSLTTWRHRYRLPDAVYLGDSDRRLRVDLTEPAHL
                     HLLRAELDRTGHVQLREAPDTSAMGWIDGRAHDIAIPLAATVTPLPRVMPRGPAIRRDH
                     GHLPATGGWQYVKLYSHPDRHTTILTNHIPVLLSTMGGEPDWWFLRYHDPAPHLRLRIR
                     LGDSDFGRIATTIGLWTAGLREAGLLGHVQWDTYYPETGRFGHGPAMRAAEVVFAADSA
                     AALAQLDAAGRRGGPHQHALIAASMVDLAIGLAGGTKAGMRLLTDGIRVPATPALDRAV
                     LDQAIRLANPHDQAALRAVPGGGPIAATWTHRRTALAAYRATLTAQGYITPDSLLPDLL
                     HLHHVRMAGTSPDLERTCARLARAAALSWTHRDRRPSKEPS"
     aSDomain        10457..10729
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BN1701_RS12440_Lanthipeptide_LanB_RRE
                     .1"
                     /evalue="9.50E-16"
                     /identifier="RREFam001.1"
                     /label="BN1701_RS12440"
                     /locus_tag="BN1701_RS12440"
                     /protein_end="243"
                     /protein_start="152"
                     /score="49.3"
                     /tool="antismash"
                     /translation="VVAHNVAFTRDGSLVIAYRQADGGGGEPVDLSIRCLDVVARVMTS
                     ARDPIVLGDLAATLAIDFPNQPRSAIDRVLDTLVAQGVLRTELRPP"
     gene            13090..14319
                     /locus_tag="BN1701_RS12445"
     CDS             13090..14319
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024582.1"
                     /locus_tag="BN1701_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_054048469.1"
                     /sec_met_domain="LANC_like (E-value: 1.5e-40, bitscore:
                     137.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPAPQALAAADTIADRLADPTLVYRAGMGRHRPQSLAGGAAGI
                     ALLHIERARCGHGDPAVAHRWLSAAARDGLSVGHNAGLYFGAPTLAFITNAAADQPGKY
                     ARALGELDTNVTALTRSRVHAAHARIDRGERPLLAEFDLIRGLAGLGSHHLHRHPDHEI
                     TRTVLDYLVRLTTPPGRSDELPGWWTDVSPNGVSSPDFPGGHANTGMSHGITAVLALLS
                     LALRHGVVVDGHTEAIGRINAWLDAWRQHDDAGSWWPGYLTHAQARAGQVDRPNRQRPS
                     WCYGTPGVARAQQLAGLATGDLPRQRDAATAMLGCLRDTAQLDRLTDSGLCHGVAGVLQ
                     TAWRMAADHTDPDLAAELPALTDRLLAHVDTAPDDPEFLDGQAGIALALHTAGTATAPV
                     TTWDACLLLA"
     gene            14354..15154
                     /locus_tag="BN1701_RS12450"
     CDS             14354..15154
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024581.1"
                     /locus_tag="BN1701_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_054048471.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6e-46, bitscore:
                     156.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQAWRQVLIHFDTWDTAEHTAVTELAPMLAQTEASGRIVSWFFV
                     RKAPCWRLRFLPADDATTEAAAFIHHRLDALHAAGRIARWVETIYEPETHAFGGPQAMD
                     TAHTLFHQDSHHILQHLATTAGGGDKRRELAVLLCCAMMRAAGLDWHEQGDVWARVAEH
                     RSLPPDTPPDRLYALQPGLRRLLTVNTTPLTQDNEPLAFLADWQAAFTNAGTNLGDMAR
                     DGVLQRGLRAVLAQHVIFAWNRIGLPHTTQSLLAHVAKAAVFDQ"
     gene            15194..16345
                     /locus_tag="BN1701_RS12455"
     CDS             15194..16345
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054048473.1"
                     /transl_table=11
                     /translation="MQVAGHTRHDGRIAQWFPLVPRPRPPCRALTQRVQEIRDLAHAAS
                     HGTRVDRVVAAAEAHNKAALILSDCGLTDMANQLCWKQYDIFQAAAPLTAKTAKLALQP
                     IINLGRLLIRAGHGDRAYQVFQRAYDAMRTGSATTIDERDIDLGGLVDTADAHRELRRF
                     LWTVLLADGTRALTTSGQWNAALRHVEHHKGIGTRLLDGRQVAILAHSTAGNLNRAINI
                     LDTTNTPEPWEQAVAAHLHARCRTINQQPAGTKIATMVNHYLHLAPEPGQAVFRTRLGL
                     AVLELTVNSNTGAAHEVAARICREALDTADAYLAWDVLNDPNSGWIASDYDRRTLATMV
                     ESSGLHRAAIPADDLDEIDQAVCASGAQLARLLTVMPASLDPR"
     gene            16443..16760
                     /locus_tag="BN1701_RS12460"
     CDS             16443..16760
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157367940.1"
                     /transl_table=11
                     /translation="MSTTWAVVRAQPTGTGDIAGTFSTPERAEILLAELDDHILVRCDE
                     ETGFRVVHYWICHARVSGDDTEIGPPNLLIGASRLAHRDHPIEEVEGVEAKDKETSWTR
                     W"
     misc_feature    complement(16890..16905)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.15"
                     /tool="antismash"
     misc_feature    16891..16904
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.63"
                     /tool="antismash"
     misc_feature    16921..16937
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.23"
                     /tool="antismash"
     gene            17040..17225
                     /locus_tag="BN1701_RS12465"
     CDS             17040..17225
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_054048477.1"
                     /transl_table=11
                     /translation="MATTGFRALMHSGELELRCTACATAGEPTGSWHLTSRAQLPERAE
                     LDDAPYVDLLKSAATA"
     gene            17307..17558
                     /locus_tag="BN1701_RS12470"
     CDS             17307..17558
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN1701_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157367941.1"
                     /transl_table=11
                     /translation="MRLDTPFPPHPTDPDTVVPDGLSTGGTVRAFVSGWFRAADTGAWL
                     AVVNYSIGHADEWKARVMVVDQLVPGHAVTRRDDSRPL"
     gene            17678..18474
                     /locus_tag="BN1701_RS34275"
     CDS             join(17678..18014,18014..18474)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012606213.1"
                     /locus_tag="BN1701_RS34275"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_172803410.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MAKRLVPDELWALAGPLVPPFEPRRQGGGTEPVDDRAVFTAIVYV
                     LTSGCSWRLLPPSFGVTVPTAHRRFSDWTRAGFWRRLHRAVLDELGSQGLIDWSRAVLD
                     GASVRAKKGGSLTGPSPVDRGKPGSKIHVLSDRRGIPLSVAVSAANTNDAAALKPLVMA
                     IPAIKSRRGPRRRKPDKLHADKAYDIKDLRTWVRDQGIAVRIARKGIETSDKLGLHRWV
                     IERTIAWTFNYRRLAIRYERHATNFTAFLTLAATLVAFKKLPT"
     gene            complement(18614..19582)
                     /locus_tag="BN1701_RS12485"
     CDS             complement(18614..19582)
                     /GO_function="GO:0050135 - NADP+ nucleosidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021640.4"
                     /locus_tag="BN1701_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIR domain-containing protein"
                     /protein_id="WP_054048482.1"
                     /transl_table=11
                     /translation="MTSDPLAAVIRFPNDVDEAARAELADALRARDVPVVHGLDLGDRG
                     PLDEFTQAVVSVAGGLADKVGDFAFASRNWLDALSRDATDGALRCVELEDRDSGVTVRV
                     TAYDPDEAIRILKPFLASAGDEPVSWLGTSWGVRQKATRADERRVFVVHGRDKRARRAL
                     YDFLRAINLQPIEWPAALGLTGQGAPYIGQVLDAVLATKVPVIVFQTPDDVAYLKVEHA
                     DDDEDLDVRPAGQARPNVLFEAGMAMALCPDRTLFVEFGKVRPFTDLGGRNVVRLFDSP
                     QRRTLLGRRLADIGCPVDDSGTDWLTAGDLTPPSTTAMPRG"
     gene            19629..22130
                     /locus_tag="BN1701_RS12490"
     CDS             19629..22130
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="BN1701_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_054048484.1"
                     /transl_table=11
                     /translation="MSAGPAEQLLDTLLDPIVAFAGTGVGHDEARDLYAAGDVGGLAAL
                     YHDEGVRAMHSGDDRTAVRMLLAERSAARRNGDTEQTASAVHFLAQHHRVRARFVPAEM
                     CNHVALTTPLRDETALYHARAWRELAAIREATADYDAGLACSARSIDVCERYPRVAAIP
                     QARVLTLLQRSALLRQRGALSDALECVQLARTLAQDEAVNSITEGQVALREAGIEKMIG
                     RPDRALAAYQRAEAIFVGRSPGNVRIARIGQVTCLREAGRADEALPVAIRVEAACRAES
                     DAYGLGQILLEKAEVLQELGDHNGVSDTLAAAAFRYLDDSGLEALRWRRHLARNLLDLG
                     QDPHAAAAHLGFVLTIAASVRRDLNRTMLALFVIYRVPQHALRSPDIRFVACRAALLGA
                     DIQRGELREPGPRWSLHGQREQIYLAAALVHAETDDAAAVAQIIETGRADVLNQLLVGG
                     YPDAGLTDMAMPSTETARLDLVFSAAAEVGAALLRETGPAPLPDLPLPGTLPTADMLGE
                     LGDVVVMVQVGEDTDHWCCVSSVWTHRTGWRTSVQAASPPIHALLRRLRSGEVLPQRGI
                     TRATWDALGSFLFPSDEIWAGTELEPRSVVVCPDPRLWQLPLGALTRGKTYLSDIAELM
                     LTPSLDTSRLVMNRRTSAIAGPALSILDPTLGGYDQELAALDAWKDGHRPISDLAELST
                     ASLLYISGHGDEAGQESALGRGRTTMHELARRELPPLVFLNGCWSGTAASRYGTDPLSV
                     AMGALLGGARTVVAGTGSIGGAGSAAVSAQALSIIGEGGSVRAAVRIAQRRVRTDHPEL
                     GPFEWAGLCVVGVDTVSDLDG"
     gene            22123..24984
                     /locus_tag="BN1701_RS12495"
     CDS             22123..24984
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025056.4"
                     /locus_tag="BN1701_RS12495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="WP_054048486.1"
                     /transl_table=11
                     /translation="MVEGSLGYDVFLCYKSEDAVAAEELRLALVAKGLTVFRDEISGGD
                     WAPLGASIEQALLRSRTLVALITPHFPISPHCREELHMALTAAYHLDAGDTSRVMAVAQ
                     GVSPDDIRPRQLTRFRLPRSGLPTAELVASIAAGVHRHDRRTFGDAPRPREPKWYPREL
                     PGDSYFRGRYAEMWELHEGLLARSKNRDRGHPVVVVNGLGGQGKTAMCLQYARLFERDH
                     PGGVFVIRLEGSAGPADVGDNLVRSRFEDQLRLIALRLGVPGPDDVPAALERLDEPYLW
                     VLDDLPSGTSGDVLMDLYAPTRAGRTLVTTRGSLTRFASHGLPLGPLGPEISRVVLTAY
                     RSAEPADRGSVAELVGLLGQHPLGLTIAAGLTTLPDFTDYRTLLADLSSSEPEQLEHAA
                     HLEHELPAGCALPFSNALLRAYHAVTDAARDALCAASVLAPTLIPMALLSAMVGGVGGD
                     IDKVADGLRVAANRGLVEELTPAAATVHALISRAIRVLPEASSRRARLRAAALEELAAV
                     METTREEYRHREVGHHLPHVRAVAGLLPGGDRWALTGDERHIMGEAGRVHAESGDTNAS
                     LRTYEALYAACAGSTAVDTYTRLCVLSGLAVAHGLEGHHTLALRMENEVAAGLTLELGP
                     DDRDVLLTQANLGLAHLAIRDYTVASSILRDTYRRSRRVLGPTHRDTLRILNNLAIAKG
                     HLGDAPAEQNRNRRVAHRYWLGAMAAWHRVGRPDDQYALDTRNGTALSYRALAMPSEAL
                     LLMRDLYQRRSRVLGQDHPNTLDALENLLILQEECQVELEARFESVLLGRVRGQGPGHP
                     STRMTLRNLVHGSLHGVTSAGGTPAALPVGVGPDGVRLDGDHVDAEIDLQGYAIDLQEA
                     RVSAFGPDDPRTMLATAYLAYALALGDHLDGQVEAAAYLAQDAYDGLADCHDDGAEHVT
                     ADDVETVRQIVEWIKEKVEYADG"
ORIGIN
        1 gaccatggtc agcacgagat tcagcgagcc ccagaacagg aacgccgtcc agtcgtcgag
       61 taggaacacc cccgcgacga tcgcgaagac caggaacacg ccaccggcca gcactccacg
      121 ccaagtcaac cgcttgaggt cgtgcatccg ctcgcgctgc tcgtcgtcca tctcgcgctt
      181 ccccacgcac caactttccc acatcaagca ggacgcagaa cgattcttgg aggtgcgtcc
      241 gggatgtcgg tcactgcggc gcgtctcgga ttccgccaac caggtccgac acacgcacac
      301 caaactgtcc ggacctggtt ggcgaatcgc aggtcagctt caccgtcctc cgacaagttc
      361 aaccggacgg gacaggtcgt gtcccgtccg gccgaagttg gcggattcca cgccaagttg
      421 gcgggggcct gcggagtccg ggtagttggc gtgacgggcg gaatggttgc tggtggcagg
      481 gccctgccgg tgtggacggg gtctcagccg ctctgcggcc ttgattccgg gttcgactcc
      541 ggtgcgggct ccagcacgat ccccggcacg actcctggcg gtgtctcgtg cggggactcc
      601 ggggttggct ccggcgatgt ctcgggccat gacagcggtg ccgggccgaa cgcgcgtcgg
      661 gcggccttga cggccagtgc ggcgacggtg gcgttggcgc cgccgccgat caccgcgccg
      721 atgccgaacg gggctacccg gccgagcacg atgatccctt gcttggtgcc gtacttggtg
      781 atgaagttcc tgcccaggac gctgttgatc tggcgcaggg ccgctgtggg cactttgcta
      841 atgagctgtc ggccccagtg ctggccggtg cgctcggcga ccttgccgat ggtcgtggat
      901 ccggacttgc cgagtaggac ccccatgacg agtgtccggc ggcgttcgat ctcgtcgagc
      961 tggaccccgt ggacctcggc gaccgagagc acgaacaggg tgctcagttc gagcgaggag
     1021 aacgcctcgc ccgccgacag tgccagcgcg atcccggtgc cgacggcggg cgctgccgcg
     1081 gcgcccccga ccgcggcgcc cgtgctagcc agagcgctga cgtacatccg ctccagggtg
     1141 cggacgacat ccgccggtgt cgcctccggg ttgcgctggc gggcccgggc gatgttcttg
     1201 cggaccagcg gtgtctgcag gccgatggcc ttgtccaaca gatcgaggat cggctggccc
     1261 cgtccgctcg acgccgggac cggtccttcg agtgcgtcag aggccacacc aagctccctt
     1321 gcgtcgtcac gttcctcgcc cagtctcacg cccgagcggc cagagccagt ccttgcgctt
     1381 gatcgtcagg cagaagctgg ccgagagcat gacgttagcg cccgtcgtca gccagaggcc
     1441 caaggctgct ccgagccggg ggtagggcac attatggccg tagaagctgg cgatggcggc
     1501 ggggatcgcg cacgtcatgg tcgttggcga gggagtcgaa cgccgaggtg acagatcgcg
     1561 gcgctgccac cgcccagcgc gccgcgtcga ccagctcggc cactgctctc gtgaacgcgc
     1621 cagcgatagc ggaccgtcgc ggagctgatc agccagctgt ctcacaagcg aacccagccc
     1681 gcgatgctcg gctcgggggc cggggtgtgc gtggtgcacg acgggttcga caacctcatg
     1741 caccaccgtt agggagacgg gggcaacgta gccgagacgg gcggcagctc ccgctgttca
     1801 catcgctgca cgcacttccc gccgcgtcca cggccatcga aacgccacgc tgatggaagt
     1861 tcggagagga aggctgctac caatacgagc cctcgatcaa ggtcgacctg tcattgacgc
     1921 gcgagcacac gcctcacgaa ctcggtgact tgatgatgac gtcgatcagg agcttccacg
     1981 actcccgatc aaccgtgaga gttccgcccg cacggtgttt ggtgtcccgg atgcccgccg
     2041 aggtgacggc caacgcgacc tcgacgcaac tctctccgtc gctggtaaag cttgacgtac
     2101 gccacctggc atcattcgac atgcatggcc cctctgacag ctccttcaca gtgcggccat
     2161 gtacctggcg atcaggtcac gcgtgtcgtg taccggcaat gcccgctctg cgatccgttc
     2221 ggctcttaga tggtaggccg cgacctggcc aggttcctgc accgatcggg cgccttccgg
     2281 cccctccgag tagccgatgc tgcgagcctc ggtgaaatcg aggagggtga acttgccgtc
     2341 caggccatcg tgcacaggca cgtcgaacgg gatgacctgc agcgtcacgt tcggcttggt
     2401 cgacagatcg agcaggtgct gaagctgttc gcggaagacg tcgctaccac cgatccggcg
     2461 gtgcagaaca gcttcctcaa ggacgcagtg caggcgcagc gggttctcgt cgcgccacag
     2521 gtggcgctgg cgatcagttc gcacatcgac gactcggtcg gcgtcgacca gcggcacacg
     2581 gagattgtca gtgagcaggg cccgcgcgta tccacgcgtc tgggccagac cagccacgac
     2641 catgggcgcg taagcgaacg acgaggacgc gagcccttcg agcccgatca acgtcctgag
     2701 ccagtccggc acaacgtcgg cgttggacgc ccaccagtcg tccgcatctg atcgaccggc
     2761 caatcgcgca atccggtcga tctgcggttg tgggacgcca tagtgcccaa gcagcgctcg
     2821 tacgacgtcg ggttgctggc ggttccggcc gctctccaga tgagcaagcc cgcctgcggt
     2881 gatgcccagg aagtccgctg cggtcgactg cttgattcgt gcctggtcgc gggcgactcg
     2941 cagttcattg ccgaccagaa agcccagagc tgttggcaag cgctcggcag ccaccatgtc
     3001 tcccttcggc caaaccgtcg gcaccgagtc ttccagcccc actcgatcac gccccaggat
     3061 ggtcacccaa tcaggggatg gattacggta aagtttaccg ctaactttat caacgcagcc
     3121 cgatgggccg cacgcgggtc gggaggaccg gcggcatccg ttcggcaacg tgctccgacc
     3181 tcccgatcag cgcagaaggc ggcggggtcg aacccacccc agttcgaccc cgccgtcccg
     3241 gttacgggag accaaatggc gatgccaact gtcatcgttg ggctggccgc gtgcgtccta
     3301 tgcgcaaggc ttggcctgct gctctggaag cgaacgcacg acttctccgt cgaggacaag
     3361 cgatgagccc cgcggccgag gccaacctcg atgcctacgc gcaggaactg ctgcgaagcg
     3421 gtggcttcct cgaccacagc ccaacgcgct cgggcaactc gatgtctctc ttgcccgcga
     3481 ccacgacggg ctcgtcgacg cattggttct ctcgccgtta ggccccggcg tggtgggacc
     3541 cagacgtgcc atgggagcac ccgcccgcac acctgcaccg cgttctgcca gcccctgacg
     3601 caattcgtct ggcgttgaac atgacccaga ccagccgccc cgcgccaact gtggccagcg
     3661 gtcgtagtca acgcgcatgc cgccctgagg tcttgacatc ggccaacgat cagtcgaggt
     3721 acctaatgca cccgaatcca cgcaccacga ggttgagcga accggcatcg agcggtcgca
     3781 aggaactacc gctgcgcaat gtcgggactc tcgtagcaaa tgccgagcaa gtggccttga
     3841 tcgctgccgc cagggtcgcc aagacgcggg ccgaactgtc acctgcgcag cgcaccagcc
     3901 cctgggtccc gatcttggtc atcaccgatc cctggctgga atgctggctg aagtgggacg
     3961 gccgagccac caccgacaac caggacaccg tcctcatcct caacaccacg acgctccctg
     4021 gactcaacaa ggtggacgtc gcggactcgg tggtgttgga cgcctacctc gacgcgttca
     4081 ccggaagcct tgccctgcgc ggttatctcg tgcagacctc gtggagcaaa caagatcgcg
     4141 cgactcaaca acgagtatgg cgacttcgcc gaaagcgcgg ctgaggatga gtaccacact
     4201 gatcgaattc ccggaatttg aggacggccg cctcgccagc ctggtccgcg ccgggaccgt
     4261 gtcggcctac ggatcgctct acgagcggca cgtcggcgcg gcgcggaacc tggcccgcca
     4321 actcaccagg tcgcccgccg aggccgacga cctggtgtcc gaggcgttcg cgaaagtcct
     4381 cgacaccctg cgccaaggcc gcggccccga ctccgccttc cgcgcctacc tgctcaccgc
     4441 tctgcgccac accgcctacg acaagacccg ccgcgacaag aaggtcgaac tctccgacga
     4501 cgtctcccag gtcagcggcg tcaaccccga ccaggtcgcg gtccccttct ccgacaccgc
     4561 cgtcgccgga ctcgaacgca gcctcgccgc ccgcgccttc gccatgctcc ccgaacgctg
     4621 gcaagccgtc ctctggcaca ccgagatcga aggccagaac cccgcccagg tcgcccccat
     4681 cctcggcctc acccccaacg gcgtctccgc cctggcctac cgcgcccgcg aaggactccg
     4741 ccaggcctac ctccaagtcc acctcgccga aaacagcagc gaccgctgcc gcgccaccgc
     4801 cgaccgactc ggcgcctggg tccgcggcgg actgtccaag cgcgagaccg cccaggtcga
     4861 actccacctc gacgactgcg aacgctgccg cgccctgtcc gccgaactcg ccgacaccaa
     4921 caccacactc ccccgccgcc actgcacctc gaccacacgg gcgctgcgat cacatcgcgg
     4981 caagacctgg tgtcggcgga cattcacccg acgaacccac accggacagg tccagtcaga
     5041 caaagcatcc aaagaggacg ccatcacaga ccgggcagcg tcgactcgtc cgacccattg
     5101 caacctgaac cgggcgcttg ggcagatctc cggctcagaa aacaaacctg cacgtgcagg
     5161 ctcacagctg gctgtccagc atggtgtccg cgccgatgcg ctcgtcccca ttggcgatcc
     5221 cctgtccatc caatcgcccg ggtcccatcc ctgttctcgg cattccgtcc ttgcttgtgc
     5281 ggttcgcgtg gcatgcgcct cccatgtcat gcgcccgagc agggtggatg ccttcctggc
     5341 cggtccgcgc gaccgtcccc cgaccgccct gaccactcgg gcgcagtcgt gcggaccggc
     5401 cccatccctt tggcggcggt cgtgatgtcc cgcgcccgcc gcctgccgtg gatcgcgctg
     5461 ctgagccgcc tgcggtggca acgcgaccgc gacctctgga cggtccgctg ccgcgaccac
     5521 gaaggacgac acacgctagt gcgggtccag atccgcgccg aaggcgtcgt tctcaacgca
     5581 tcgcgtccgg gcgctctcgc cttcacccct ctggcggtgg gccgactacg tgccgcgctc
     5641 cgcgacgcgg tggtcgccca cgccgtattc gctggatcca ccaccaagga catcgactat
     5701 gaccgcgacc ttgatcacga ccttgaccgc tccgcgatcg gcggcacgga tgcccacgcg
     5761 gcatgacctc acccgggcgc tattggagta ccggcagcac gggtgggacg cgttcaccga
     5821 cgaacacggc aacatcatga tcggcgtcgg cgagcacttc gacgccctca ctttccccga
     5881 gccactggcg gcggcggtcg ccgaggccgt gtcgaccgca ccgctgttcc tcgacgcacg
     5941 cacccgccgc tgcacccttc tgaccgccat cgcgtgcggc ccattggagc tgccacccag
     6001 cctcgccgac gcgcgggttc gcgctctgcc acgccgcacg cccctgctcc tgcccctgac
     6061 cgaccagggc ggcgaccgga gctggctgac ccggccgatc tcgcctgcgc tgccgccgtg
     6121 ggacaccgcc gttaccgcca tccgtcgcgc cgcgactggg tggttccggt gaccacggcg
     6181 ctgcggccgt cgacgccgct ctacgagccc ggactgctgc gcgcgctgcg catggtcgaa
     6241 cgcgatcagg tcggtgctta cggtctcacc acgccgctgc gaacgcggac cgacgaggcg
     6301 gccccggcct ggttgatcag cgcgctgttc gtgctgcgcc gcgacgacct cgtctgcctc
     6361 gatccacccc gaggcgccga cctgtggcgc tcggcgaccc tgacggcgct cggccgcgat
     6421 gtgctcgccg cctggactca ggaccgaccc gcgccagtgc ggccgtttca ggcggtcggg
     6481 tcggtcaccg cgatcctgca ctacatcgcg accgaggacg gtcgaccgcg caccctggcc
     6541 accgaggacg ggccgcgctg gatcgcgttg tgccgggcgt ggactcatcc cgcgcgggta
     6601 tcgcacggca gcgggctggt ccggtgtgct cgatgcgccg cccaccttgt gccgggtgcg
     6661 ccgtgacagc cgccgccgtc ccgttcgggg agcccatcat gaaccaccac cacgctgagc
     6721 cggtatggcg gctgtcgtgg ggcagcagcc cgttctaccg cgggcgggca cacctcgtcg
     6781 cgccgggttg gccccgtgct ttgtgcggga ccgtcgccga ggcgaccgac ggcaagcccg
     6841 cgccgctggt gtgcccggag tgcgcgatcg tcttcgccga caccgcgatc gcccgcatgc
     6901 tggccgatcg cggcggatgg gagcggtggt gaccacgaca cacggtgatc gccgcatccg
     6961 actgctgggc aagctgctgc accccgcgcg cgacgccaga gactggtggc gcctggagtt
     7021 gatcgcgccg ctgcccgtag ggatcgacca cacgacgttg gggacctacg agcagggcac
     7081 ccgtcaccgc accgtggcca ggctgttcga gctgtgtgac acgctcggcg tgcgggcaag
     7141 cgagatcctg gccgcgatag agaacgatgc cgacaacgcc accgagaacg acagcgaggc
     7201 acaggtcggc ccggcgcggt tcgatggggt gacggtcgat ggtgcgacgg tcgatctggt
     7261 cgcgatgtcg gtgtcgcacc cgtcgtcgtt gcgtccgcta cggctgtggg ccgagcaccg
     7321 ccatgtccgg ttgaccccag cggcgatcac ggtcctcgcg ggtctgcgcg gcatgagtcc
     7381 gccggtgacc cgagggcgat tacaccgccg gctcaccatc gacgcaagaa cggtgtgaca
     7441 ccgctatccg tctcgattgg acacaggatg ctcgacaaga tcacgctcga cccgccgcga
     7501 ccggtgccct acaagaaatc tgagcatctc tgcgcacgca tcgtgggcgt ggcgttgcga
     7561 caagcggtca aggagcgcgg gctgacctat gccgagatgt ctcaacgggt cggcgtgtcg
     7621 atcagcagca tctcccgggt ggtcggcggc acaaccaatg tgcggttgga ggacatcgtc
     7681 gcggtcctcg cggtgtgcgg ggtcaccggt gagcggcgcg accgcatcct cggcatggcc
     7741 aagcgccggg gtcatgacag cgacgcgctg ctcctcagct atggcaccga acacggtgtc
     7801 gacaccgccg cgctggacga cttggcgagc ctggccacca gcgtcaccgt ggtcgcctcc
     7861 accgcccacg ccatcgccac gagtcgccca ctcgggaaca ctcgctacac ctttctggtc
     7921 acggcgttcg cgttggccgc catgcccgac gaccaacgcg ccgacctggc cacgctgacc
     7981 cgtgtgccga ccgtgtgtct gcgcgttctc gaccacggtc ccatcggtga gtccttcgag
     8041 ctgctgacct tcgaagaccg caccaccgcc gtggcggtcc ggctgcgcac ctcgcacctg
     8101 atcttcgacc gcggggacac cgtgctcgcc taccgccggc acgccaaagc cctcaccacc
     8161 cgagccctca ccccccaaca aagccgtcga ctcatcaccc aacgcgccac cacgccggaa
     8221 tgacccggcc ggcgcgagac ctcggcaccg gcatcggcgc gccacgcact ggaccgaggc
     8281 ctcgcccgac ctgtcggtgc tctggtcgaa cctgatccac ggcgagctcg accgaccgcg
     8341 tcgccagcat cgggctcgcc cagcgagtcc gtctttgacc gggacaccct cacaccgccc
     8401 aaagagagct gaaagagtga tcacatgaac acactccgag atgacgctgt tggtcgtgac
     8461 accccggggc ccgcctcgac gcgcatcgac gtgcttcgcg cggcgatggt cgacgaactc
     8521 cgccggatgg gcgcgattgt caccgagcgt gtcgcggacg cggtcctcgc ggtgccccgg
     8581 catgtcttcg cgccggtggg cgagccagcg gagcgggtct atgccccgac cacggccatc
     8641 gtcaccaagc gcaacgggca gggcgcggcg atcagttcgt tgtccgaggc gcacatccag
     8701 gccacgatgc tcgaacaggc gcggatcgag cccgggatgc gtgtcctgga gatcgggacc
     8761 ggcggctaca acgcctcgtt gatcgcggag ctggtcggcg agtcgggcca ggtcacctcg
     8821 gtggacatcg actccgacat cgtgtccagc gcacggggat gcttggccga ggcgggatat
     8881 gagcgggtcc gggtggtgtt ggccgacgcg gagcatggtg tgcccgatcg cgccccgttc
     8941 gatcgggtga tcgtgaccgc cggggcatgg gacatcccgc ccgcgtggat cgcccagctc
     9001 accgatcggg gtcggatcgt gctcccgctg cggctgcgcg gcctgaccag gtcggtcgcg
     9061 ttcgagcgcg acggggacca cctggtgagc ctgagctacc gcctgtgcgg gttcgtcccc
     9121 atgcaaggcg caggcgcaca cgtggaacgc acggtgccgc tcgacgggaa cgaggtcggc
     9181 atccgggtcg acggcgccca tgaactcgac acagacgccc tgcgggagtc gttgttcggc
     9241 ccgcgtgtcg agcgctggtc cggggtggtg ttcgaccagg tcgacggaat ggacttcttc
     9301 gtcgccacca cctcccccgg cttcggtctg ctcaccgcga cgtcagcggc gatcaagcgc
     9361 gggttggtcg gtccgtcggc gattcggggt gtgcccacga tcgtgcgcgg cgccggcttc
     9421 gcctaccgga tgaagcgtcc gatcgaggga accgacgact tcgagaccgg cgtgctggcg
     9481 cacggcccga acgccgagga cctcgcgcgg gagctcgtcg atctgctgcg cgtctgggac
     9541 cgcgaccacc ggcacggtgc cggggcgcgg atcgaggtcc atcccgccgc cacgccagcg
     9601 gcagggctgg gtgacgggct ggtcgtggac aagatccaca cccggattgt catttcctgg
     9661 ccctgaccga ggggcgggat ctggcttacg ggcacctttc cgggtgcccg gaacgaaaca
     9721 ccaccatcac atcgaaaggg aggttccgtg gccattcaga tggatcacac gcccacggcg
     9781 acggcggact tggactggga tcttgacatc accatcgtgg agtcgggcgg ggtcgtcgat
     9841 gacctgctgc ggctgaccga cgacggctgc ggcgcgacgt gcgagtcggc ctgcaactcc
     9901 tgcccgtaga gcgagaccgc tcgatcacct gtccggtaga ggtctgtgcc cggcggcgcg
     9961 ccgcgccgcc gggcacggct ttgcgttgtg gggagcgaaa gtgttccacg tcgtcgatga
    10021 cgcggtgctg ctgcgcgcat ccgcgtacca gcccaccgtc atgccttggc cggatttggc
    10081 cgacacctcg atcgagggca tcgagcagtg gcgggcctgg ctgggccagg tctgggcgtc
    10141 cacggagttc gccgcggccg tcgaggcggc cagcccggcc ttggcccggc gcgtccggca
    10201 gatccgcgac ggacagccac ggcccgaacg cgaggtccgg cgcgcggtgt tggccgtcgc
    10261 ccgctacctg ctgcgcgcgc agggccggtc gacaccgttc gggttgttcg ccggtatcgc
    10321 gccgtgcacc ttcggcgatg gcccggtggt ccgcgtcggc gacgaccatc gggtgaccac
    10381 gagggtggac acgacgtggc tggccacggt gatcacgcgc ctggagaccg accccgttct
    10441 gcggcagcgg ttggtggtgg tcgcgcacaa cgtcgcgttc acccgcgatg gctcgctcgt
    10501 catcgcctac cgccaggctg atggtggcgg cggtgaaccg gtggacctgt cgatccggtg
    10561 cctcgatgtc gtcgcccgtg tcatgaccag cgcgcgggac ccgatcgtgc tgggggacct
    10621 ggcggccaca ctggcaatcg acttcccgaa ccagccgcgg tcggcgatcg accgggtgct
    10681 ggacaccctg gtggcccagg gtgtcctgcg caccgagctg cgccccccga tgaccagcac
    10741 cgacccgctc gggcacgtca tcgccaccct cacccgggca gagtcggaca cgccggccga
    10801 cacccgtgaa ctcgtggacg cactgcgcgc gattcacaca gacctggcca ctcacgacca
    10861 gtccagcgtg cccgcgctca accacaccct gcgagccgcg accgaggcgg cgatggcagc
    10921 cgtgtccggt accgaacggc cactcgcccc ggacctgcta ctcgacagcg acctcctcct
    10981 gcccgagacg atcgcccggg aggccgcggc cgccgccgcg gcactggtgc ggctgacccc
    11041 cgaaccgttc ggccccccga attggcagac ctaccacggg caattcctcg aacggttcgg
    11101 cctcaacgcg gtcgtccccg tgaccgacct ggtcaacccc gacaccggcc tcggctttcc
    11161 ctccggctac cgggactccc tccagccacc gcccgctggg cgggcaatgt ccgatcggga
    11221 cagcgccctg ctcggcctgg cccagaaagc ggccatggag caggaacacg agatcgtgct
    11281 cgacgacgag atgatcaccg aactcgcggt cgacgacctg cgcacagcca gcgtgcaacc
    11341 acacacgcag ctgcgggtcc gggtccacgc gcccaccctc gacgccctcc tgcgcggtga
    11401 tttcgagctg gtcgtcaccg gtgtgtctcg gtcggcgggc ctgtcggccg gtcggtttct
    11461 cgacccgttc gcccccgagg atcgcgcccg gatgcttcgc gcctaccagg gcctgccgac
    11521 gatcaccgag aacgcgctgc cggtgcagct gtcgtgcccg ccgctgtacc cacgggcgga
    11581 gaacgtcgcc aggacacccc gggtcctccc ccacgtcctc tccctcgccg agcacccgcc
    11641 ccggcacgcc gacacgcacc tggtcccgat cgacgatctc gcggtgaccg cggacgcccg
    11701 gcggctgcac ctgatgtcga tgtcgcggcg gcgcgcggtg gaaccgttgt tgttcagcgc
    11761 ggtggaactg gtcaaacaca gccacccgtt ggtgcggttc ctgaccgaga tcagcaccgc
    11821 ccgcgccgcg gcgtgcaccg cgttctcctg gggcgccgcc agtcgcctac cgttcctgcc
    11881 caggctgcgc taccaacgca ccatcctgtc cccggcccgc tgggtcctca ccgccaccga
    11941 cctgccaagc ccatcggccc cgtggcagga ctgggcgaag agcctcacca cctggcggca
    12001 ccgataccgc ctgcccgacg ccgtctacct cggcgacagt gaccgccgcc tgcgcgtgga
    12061 cctcaccgaa cccgcgcacc tccacctgct gcgcgccgag ttggaccgta ccgggcacgt
    12121 ccagctccgg gaagcaccgg acaccagcgc catgggctgg atcgacggac gcgcccacga
    12181 catcgcgatc cccctcgccg ccaccgtcac accgctgccg cgggtgatgc cacgcggccc
    12241 ggcgatccgc cgcgaccacg ggcaccttcc cgccacgggc gggtggcagt acgtgaagct
    12301 ctacagccac ccggatcgac acaccaccat cctcaccaac cacatcccgg ttctactgtc
    12361 cacaatgggc ggtgaacccg actggtggtt cctgcgctac cacgacccgg cgccgcatct
    12421 gcggctgcga atccggctcg gcgacagcga cttcggccgg atcgccacca cgatcggact
    12481 gtggacggcc gggctgcgcg aggcaggtct gctcgggcac gtccaatggg acacctacta
    12541 ccccgagacc ggccggttcg gccacgggcc ggcgatgaga gcggcggaag tggtgttcgc
    12601 cgccgactcc gccgccgccc tcgcccaact cgacgccgcc gggcggcgtg gcggcccgca
    12661 ccagcacgcc ctcatcgccg cgagcatggt cgacctggcc atcggcctcg ccggcggcac
    12721 caaagccggg atgcgcctac tgaccgacgg catccgcgtt cccgccaccc cggcgctcga
    12781 ccgcgccgta ctcgatcagg cgatccgatt ggccaatccg cacgatcagg ccgccctgcg
    12841 cgcagtgccc ggcggcggcc ccatcgccgc cacctggaca caccggcgca cggcgctggc
    12901 cgcctaccgc gccaccctca ctgcccaggg atacatcacc ccggactcgc ttctgccgga
    12961 tctgctgcac ctgcaccacg tccgcatggc gggaacctcg ccggacctcg aacgcacctg
    13021 cgcgcgcctg gcccgcgccg ccgcgctgag ctggacccac cgtgaccggc gtccgtcgaa
    13081 ggaaccctca tgatctcgcc cgcgccgcag gcgctcgccg ccgccgacac catcgccgac
    13141 cggctcgccg accccaccct cgtctaccgg gcgggcatgg gccgccacag gccgcagtcc
    13201 ctcgccggcg gggccgccgg catcgccctg ctgcacatcg aacgagcccg ctgcggccac
    13261 ggcgaccccg ccgtcgccca ccgctggctc tcggccgccg cacgggacgg gctgagcgtc
    13321 ggtcacaacg cgggcctgta cttcggcgcc cccaccctgg cgttcatcac caacgccgcg
    13381 gccgaccaac ccggcaagta cgcgcgggca ttgggtgaac tcgacaccaa cgtcaccgcg
    13441 ctcacccgca gcagagtcca cgccgcccac gctcgcatcg atcgcggcga gcggccactg
    13501 ctggccgagt tcgacctcat ccgcgggctc gccgggctcg gcagccacca cctgcaccgc
    13561 caccccgacc acgagatcac ccgcaccgtc ctcgactacc tggtccgact gaccacacca
    13621 ccgggccggt cggacgagct gcccggctgg tggaccgacg tctcacccaa cggggtatca
    13681 agcccggact tccccggtgg gcacgccaac accggaatgt cgcacggcat cacggcagtc
    13741 ctggcgttgc tgtccctggc actgcgccac ggagtcgtcg tggacgggca caccgaggcg
    13801 attggacgga tcaacgcctg gctcgacgcc tggcgccagc acgacgacgc cggatcatgg
    13861 tggcccggct acctcaccca cgcccaagcc cgcgcaggcc aggtcgaccg gcccaaccgg
    13921 caacggccgt cctggtgcta cggaaccccc ggcgtcgccc gcgcccagca actcgccgga
    13981 ctcgccaccg gcgacctgcc acgccaacgt gacgccgcaa ccgcgatgct cggctgcctc
    14041 cgcgacaccg cccagctcga ccgcctcacc gacagcggcc tgtgccacgg tgtcgccggg
    14101 gtcctgcaga cggcgtggcg catggccgcc gaccacaccg atccggacct ggccgcagag
    14161 ttgccagccc tcaccgaccg gctgctcgcc cacgtcgaca ccgcacccga cgatcccgag
    14221 ttcctcgacg gccaagccgg tatcgcactc gcactacaca ccgccgggac cgcgaccgca
    14281 ccggtcacga cctgggacgc ctgcctactc ctggcctaac aaaccagaac ccccacggaa
    14341 gtagggaaac agcgtgagcc aggcctggcg gcaagtcctg atccacttcg acacctggga
    14401 caccgccgaa cacaccgcgg tcaccgaact cgccccgatg ctcgcgcaga ccgaggcgag
    14461 cgggcggatc gtctcctggt tcttcgtcag aaaagccccg tgctggcgcc tccggttcct
    14521 gcccgccgac gacgccacga cggaggcggc agccttcatc catcatcggc tcgacgccct
    14581 ccacgccgca gggcggatcg cacggtgggt cgagaccatc tacgaacccg agacccacgc
    14641 cttcggcggc ccccaagcga tggacaccgc ccacaccctg ttccaccagg acagccacca
    14701 catcctgcaa cacctcgcca ccacagcggg cggtggggac aagcgccgcg aactggcggt
    14761 cctgctctgc tgcgccatga tgcgcgccgc cggcctggac tggcacgaac aaggcgacgt
    14821 ctgggcccgc gtcgccgaac accggtccct gccacccgac acaccgcccg acagactcta
    14881 tgcgctgcag ccaggtctgc ggcggctgct caccgtgaac accacacccc tgacacagga
    14941 caacgagcca ctcgcgttcc tggccgactg gcaggccgcg ttcaccaacg cgggcaccaa
    15001 cctcggggac atggcccgcg acggcgtcct ccaacgcggc ctgcgcgctg tgctcgccca
    15061 gcacgtgatc ttcgcgtgga accggatcgg cctgccccac accacccaga gcctgctcgc
    15121 acacgtcgcc aaagccgccg tcttcgacca gtaacccacc gaacccagct acgtgatcac
    15181 gaaggaggtg gccatgcaag tagccggtca cacgcgccac gacgggcgga tcgcacagtg
    15241 gttcccgctc gttccccgcc cccgcccgcc ctgccgagca ctcacacaac gggtccagga
    15301 gatccgcgac ctcgcgcacg cggcatccca cggcacacgc gtcgaccgcg tcgtcgcagc
    15361 cgccgaagcc cacaacaagg cagccctcat cctcagcgac tgcggcctca ccgacatggc
    15421 caaccagctg tgctggaagc aatacgacat cttccaggcc gccgcaccgc tcaccgcgaa
    15481 gaccgcgaaa ctcgccctcc aaccgatcat caacctcggc aggcttctca tccgagctgg
    15541 ccacggcgac cgggcctacc aggtcttcca acgcgcctac gacgccatgc gcaccggatc
    15601 cgccacgacg atcgacgagc gcgacatcga tcttggcggc ctggtcgaca ccgccgacgc
    15661 tcaccgtgaa ctccgccgat tcctctggac cgtgctcctg gccgacggca cccgagccct
    15721 caccaccagc ggccaatgga acgccgccct ccgacacgtc gaacaccaca agggcatcgg
    15781 cacccggctc ctcgacggcc gccaagtcgc catcctcgcc cacagcaccg caggcaacct
    15841 caaccgcgcc atcaacatcc tcgacaccac caacacgcca gagccctggg aacaagccgt
    15901 cgccgcgcac ctgcacgccc ggtgccgcac catcaaccag caacccgccg gcacaaagat
    15961 cgccaccatg gtcaaccact acctccacct cgccccggaa ccagggcagg cggtgttccg
    16021 aacccggctc gggctcgccg tcctcgaact caccgtcaac tccaacaccg gcgcagcaca
    16081 cgaggtagcc gccagaatct gtcgagaagc cctcgacacc gccgacgcct acctggcctg
    16141 ggacgtactg aacgacccca acagcgggtg gatcgcctcc gactacgaca gacgcacact
    16201 ggccaccatg gtcgagtcgt caggtctaca ccgcgcagcc attccagccg atgacctcga
    16261 cgagatcgac caagccgtgt gtgccagtgg cgcgcagctc gcccggcttc tcacagtgat
    16321 gccagcgtcg ctggacccgc gatgatctcg gcgcgttccg gcaacaccgc tcccccgagc
    16381 tcgctcaccc gaccgagcga acctccacca cccttcggat aggaaccgac atcatggcga
    16441 ccatgagcac cacctgggcc gtcgtccgcg cacagccgac agggaccggc gacatcgcgg
    16501 gaaccttcag cacacccgaa cgcgccgaga tccttctcgc cgaactcgac gaccacattc
    16561 tggtccgctg cgacgaggaa accggcttcc gagtcgtcca ctactggatc tgccacgccc
    16621 gcgtcagcgg ggatgacacc gagatcgggc ctcccaacct gttgatcggg gccagccgcc
    16681 tggctcaccg cgaccacccc atcgaagaag tcgaaggtgt cgaggccaaa gacaaggaga
    16741 cgagctggac tcggtggtaa gcggccaagc catccatcac ttctacgcct acgccagcag
    16801 cagcggccgc gcccaagaac tcgcagaaac ccatgcccgg aaactgctcg cacgcgcacg
    16861 ctgacccacc gcgaccagca aagatcgact cgaacatacg ttctaccggg tggtacgttt
    16921 tgtactatgt aggcgcgatc ccagtcaacc accgaaggct cactcaggta ccgctccgac
    16981 ggcctcggag gccgcgtcgc catcctgccc gcagcctgca gacagggcct ccaaccccct
    17041 tggccaccac cggattccgg gcgctgatgc actccgggga actcgaactt cggtgcaccg
    17101 cgtgcgccac cgcgggggag cccaccgggt catggcacct gacgtcgcgc gcacagctcc
    17161 ccgagcgggc cgaacttgac gacgcgccct acgtggacct gttgaagtcc gccgccacgg
    17221 cgtaggaccc gatgctcaac actccttaca cccgctggag cggcgacggc ctgcaaggac
    17281 gccacgcgca gtagacccct gcgtgggtgc ggttggacac gccgttcccg ccgcacccga
    17341 ccgacccgga cacggtcgtc ccggacggat tgagcacggg cggaaccgtg cgcgcgttcg
    17401 tgtccggatg gttccgcgcg gcggacacgg gtgcgtggct ggcggtggtg aactactcga
    17461 tcggtcacgc cgacgagtgg aaggccaggg tgatggtggt tgaccaactc gtccctggcc
    17521 acgcggtcac ccgccgcgac gacagccggc cgctgtgacc tctccatgtt ctgaaggtgt
    17581 gcgacgtcat ctgctattac tcctggccag gtgcttagag cgcgtctcat gtggatctcg
    17641 atggtcggtt ctgacatgat cttgagctgt ggccgtgttg gcgaagcggt tggtgccgga
    17701 cgagttgtgg gccttggcgg gtccgttggt tccgccgttc gagcctcgtc ggcagggcgg
    17761 tggcaccgaa ccggtcgatg accgggcggt gttcaccgcg atcgtgtatg tactgaccag
    17821 cggttgctcg tggcggttgt tgccaccgtc gttcggggtg acggttccga ccgcgcatcg
    17881 gaggttcagt gattggacca gggccgggtt ctggcggcga ctgcaccgcg cggtgctcga
    17941 cgaactcggc tcgcagggct tgatcgactg gtcccgcgcg gttctggacg gtgcgtccgt
    18001 ccgcgcgaaa aaaggggatc tctgaccggc ccgagtccgg tcgaccgggg caaacccgga
    18061 tcgaagatcc acgtcctatc cgaccggcga ggtattccgc tgtcggtggc cgtttccgcg
    18121 gccaacacca acgacgccgc cgcgctcaaa ccgctggtca tggcgatccc cgcgatcaag
    18181 tcacgccgcg gaccacggcg ccgcaagccc gacaaactcc acgcggacaa ggcctacgac
    18241 atcaaggacc tgcgcacatg ggtccgcgac caaggcatcg cggtcaggat cgcccgcaag
    18301 ggcatcgaaa ccagcgacaa actcggcctg caccggtggg tcatcgaacg caccatcgcc
    18361 tggaccttca actaccggcg gctcgccatc cgatacgagc gccacgcaac caacttcacc
    18421 gcgttcctca cactcgccgc caccctggtc gcgttcaaga aactccccac atgagacgcg
    18481 ctcttagcag cccacggatt ggttcgaaca acgacctcag tcgcggtgac gcggacaatc
    18541 ctcaccctgc ccctcgtagc ggcacgatcg tccagattgg tccagacctt accgcaggag
    18601 tctcgtcgcg ccattacccc cgaggcatcg ccgtagtgct cggcggggtg aggtcacccg
    18661 ccgtcagcca gtccgtgccg ctgtcgtcca ccgggcagcc gatgtcggcc aggcgccgcc
    18721 ccagcagcgt tcgccgctgg ggcgagtcga agagccgcac gacgttgcgt ccgccaaggt
    18781 cggtgaaggg gcgaaccttg ccgaactcga cgaacagggt tcggtccgga cacaacgcca
    18841 tggccatgcc cgcctcgaac aacacgttcg gccgagcctg tccggcgggc cgcacgtcga
    18901 ggtcctcgtc gtcgtcagcg tgctcgacct tgaggtaggc gacgtcatca ggggtctgga
    18961 acacgatcac cggcaccttc gtggcgagga cggcgtccag cacctggccg atgtacggag
    19021 cgccttgccc agtcaaaccc agcgcggcag gccactcgat tggctgaaga ttgatcgcgc
    19081 gcaggaagtc atacagcgcg cgccgggccc gcttgtcccg accgtggacc acgaataccc
    19141 gtcgttcgtc ggcgcgggtg gctttctgac gcacacccca agacgtcccg agccagctga
    19201 ccggctcatc tccggccgaa gccaggaaag gcttgagtat ccgaatcgcc tcgtcggggt
    19261 cgtacgccgt gactcggacc gtgacaccgc tgtcccgatc ctcgagttcc acgcaccgga
    19321 gcgcgccatc cgtggcgtcg cgggaaagcg cgtcgagcca gttccgggag gcgaaggcga
    19381 agtcgccgac cttgtccgcc aagccacccg cgacactgac aaccgcctgc gtgaactcgt
    19441 cgaggggccc acgatcgcca aggtcaaggc catggacgac tgggacatca cgcgcgcgca
    19501 gcgcatcggc cagttccgct cgggcagcct catcgacatc gttgggaaat ctgatcaccg
    19561 cggcgagcgg atcactggtc atcacctgat gatgtcatcc cgccgacctc gcgtggttac
    19621 atggtttgat gagcgccgga ccagccgagc aactgctcga cacgttgctc gacccgatcg
    19681 tcgcgttcgc cggaacaggg gtcggccacg atgaggcgcg cgatctctac gccgcggggg
    19741 atgtcggcgg cctcgccgcg ctctaccacg atgaaggcgt gcgggccatg cacagcggcg
    19801 acgaccgtac agcggtccgg atgctgctcg ccgagcgaag cgcggccagg cgcaacggcg
    19861 atactgagca aacagcttca gcggtccatt tcctcgccca gcaccaccgg gtccgggccc
    19921 gctttgtccc cgcggaaatg tgcaaccacg tggcgctcac gacgcccctg cgggatgaga
    19981 ccgcgctgta ccatgcccgc gcctggcggg aactggccgc gatccgtgag gccacggcgg
    20041 actacgacgc aggactggcc tgctccgcgc ggtcgatcga tgtgtgcgaa cgctacccac
    20101 gagtcgccgc cattccacag gcgcgcgtgc tgactctgct acagcgttca gcgttgctcc
    20161 ggcagcgcgg agcgctcagc gacgctctcg agtgtgtgca actggcccgc acactcgccc
    20221 aggacgaggc cgtgaactcg atcacggagg gacaggtggc gctgcgcgag gccgggatcg
    20281 agaagatgat cgggcgaccg gatcgcgctc tggccgcgta tcagcgagct gaggcgatct
    20341 tcgtcggccg cagcccgggc aatgtgcgga tcgcgcggat cgggcaggtc acctgccttc
    20401 gggaagcggg cagggccgac gaggctctcc cggtggccat ccgggtggag gccgcgtgca
    20461 gagctgagag cgacgcgtac ggactgggcc agatcctctt ggagaaggcc gaggtgctcc
    20521 aggaactggg tgatcacaac ggagtctcgg acaccctggc cgccgcggcg tttcgatacc
    20581 tggacgactc cgggctcgaa gcactgcggt ggcgccgcca tctggcccgc aacctgctcg
    20641 acctcggcca ggatccccac gccgcggccg ctcacctggg tttcgtcctc acgatagccg
    20701 caagcgtgcg acgcgacctg aaccggacca tgctggcact gttcgtcatc taccgcgtgc
    20761 cccaacatgc gttgcgctcg cccgacatca ggttcgtcgc gtgccgggcc gctctgctcg
    20821 gtgccgacat ccagcggggt gaactgcggg agcccgggcc tcgttggtca ttgcacggcc
    20881 aacgcgagca gatctatctc gcggcggcgc tggtgcacgc cgagaccgac gacgccgcgg
    20941 ccgtcgccca gataatcgag accgggcgcg cggacgtgct caaccaacta ctcgtgggcg
    21001 gctatccgga cgctggcctg accgacatgg cgatgccgtc cacggaaacg gcgcgtcttg
    21061 acctcgtttt ctccgccgcg gcggaggtcg gggccgcgtt gctacgggaa accggtccag
    21121 ccccgctacc cgacctgccg ctgccgggca ccctgcccac agcggacatg ctcggtgaac
    21181 tcggcgatgt cgtggtcatg gtccaggtcg gagaggacac cgaccactgg tgctgcgtca
    21241 gttcggtctg gacacaccga accggttggc ggacatcggt tcaggcggca tctcccccga
    21301 tccatgccct gctacgaaga ttgcggtcgg gtgaggtgtt gccgcaacgg ggtatcacac
    21361 gcgcgacctg ggatgcactc ggatcgttcc tcttcccgtc cgacgagatc tgggcgggta
    21421 ccgaactcga gccccgctcg gtcgtcgtgt gccctgaccc ccggctgtgg cagctcccac
    21481 tcggcgcact cacccgtggt aagacctatc tgtcggacat cgcggaactg atgctcacac
    21541 cgagcctcga cacctcccgc cttgtgatga accgcaggac cagtgccatc gccggaccgg
    21601 cactgagcat cctggacccc acgctcggcg gatacgacca ggaactggcc gcactcgacg
    21661 catggaaaga cggccaccgt cctatctcgg acctggcgga gctctcgacc gcgtcgttgc
    21721 tctatatcag cggtcatggt gacgaagcag gccaagagtc agctctgggg cgtggccgga
    21781 cgacgatgca cgagctggcg cgacgggaac tgccgccact ggtcttcctg aacggatgct
    21841 ggagcggcac cgcggcgagc cgatacggta cggacccact aagcgtcgcg atgggcgccc
    21901 tgctcggtgg agcgagaacc gtcgtcgcgg gcacaggttc catcggtgga gctgggtcgg
    21961 ccgccgtcag cgcccaagcg ctctcgatca tcggcgaggg cggatcggtc cgcgcggcgg
    22021 tccgcatcgc ccagcgtcgc gttcggacgg atcatcctga gctcggcccg ttcgagtggg
    22081 caggcttgtg tgtggtggga gtcgacacgg tgagtgatct tgatggttga gggcagcctg
    22141 ggctatgacg tattcctctg ctacaagtcc gaggacgccg tggccgccga agaactacgg
    22201 cttgccttgg tcgccaaggg cttgactgtg ttccgcgacg agatcagcgg cggcgactgg
    22261 gcgccgctcg gtgcctcgat cgaacaggcc ctgctgcggt cgcgcacact cgtcgccctc
    22321 atcaccccgc acttcccgat cagtccgcac tgccgcgaag aactgcatat ggcgttgacc
    22381 gcggcgtatc acctcgacgc gggcgacaca tctcgggtga tggccgtggc tcaaggagtc
    22441 tcgccggacg acatccggcc tcgacagctg accaggttca ggctgccccg ctccggattg
    22501 ccgacggccg agctcgtagc gtcaatcgcc gcaggtgtcc accggcacga ccgcaggacc
    22561 ttcggggacg cgccgaggcc gcgcgagccg aagtggtatc cccgagaact accgggagac
    22621 agctacttcc gtggccgcta cgccgagatg tgggagttgc acgagggcct gctggcccgg
    22681 tcgaagaatc gcgaccgagg ccaccccgtg gtggtggtga acggactggg cggccaggga
    22741 aagaccgcga tgtgtctgca gtacgcgcga ttgttcgagc gcgatcatcc aggtggcgtg
    22801 ttcgtgatca ggctggaagg cagcgcgggc ccggccgatg tcggggacaa ccttgtccgg
    22861 tccagattcg aggaccaact caggctcatc gccctgcggc tgggcgtccc aggcccggac
    22921 gacgttcccg ccgcactgga gcgactcgac gagccttacc tgtgggtgct cgacgacctg
    22981 ccgtccggga cgagcggcga cgtcctgatg gatctttacg caccgacgcg ggcaggccgc
    23041 acactcgtca ccacccgcgg gtctctgaca agattcgcgt cccatggcct accgcttggt
    23101 ccactcggcc cggagatcag ccgtgtggtg ctcaccgcct accggtccgc tgaacccgcc
    23161 gaccgcggat cggtggcgga actcgtcgga ctgctcggcc agcacccact tgggctgacc
    23221 atcgccgccg ggctgacgac acttccggac ttcaccgact accgaactct gctggcggac
    23281 ctgtcgtcaa gtgagcccga acagctcgag cacgcggcgc acctggaaca cgaactgccc
    23341 gcgggttgcg ctcttccgtt ctcgaacgcg ttgctgcgcg cctaccacgc ggtcaccgac
    23401 gcggcgaggg acgcgctctg cgcggcgagc gtcctcgcgc cgacgttgat cccgatggcg
    23461 ctgctgagcg ccatggtggg cggagtgggg ggtgacatcg acaaggtcgc cgacgggctg
    23521 agagtcgccg cgaaccgcgg gttggtcgag gaactgacgc ccgcggcggc cacggtccat
    23581 gcgttgatct cacgtgcgat cagagtgctc ccggaggcgt cgagccgacg cgcacggctc
    23641 cgcgcggccg cgctggagga actggccgcc gtcatggaga ccacccgcga ggagtaccgg
    23701 catcgtgagg tcggccatca cctgccacac gtgcgcgctg tcgcgggcct gctgccaggt
    23761 ggtgaccgct gggcgttgac gggcgatgaa cgccacatca tgggcgaagc cggtcgagtg
    23821 cacgcggaat cgggcgatac caatgcctcg ttgcgcacct acgaggctct ctacgccgcg
    23881 tgtgcgggct cgactgctgt cgacacgtac accagacttt gcgttctcag tggactcgcc
    23941 gtcgcccacg gtcttgaggg ccatcacacg ctggccctgc gcatggagaa cgaggtggcc
    24001 gccgggctga ccctcgagct gggacccgac gatcgggacg tgttgctcac ccaggccaac
    24061 ctcggtctcg cccacctcgc catccgggac tacaccgtgg cgagctcgat tctgcgggac
    24121 acgtaccggc gaagcaggcg tgtgctcggt ccgacgcacc gggacacact ccggattctc
    24181 aacaacctgg ccatcgccaa gggacatctt ggtgacgcgc ctgccgaaca gaacaggaac
    24241 cgccgcgtcg cccaccgata ttggctgggc gcgatggcgg cctggcacag ggtcggcagg
    24301 ccggatgacc agtacgcgct cgacacccgg aacgggacag cgctgagcta tcgggcactc
    24361 gccatgccca gcgaggcctt gttgctgatg cgagacctgt accagagacg gtcgcgggtt
    24421 ctcggccaag accatccgaa cactctggac gcattggaga atctgctcat cctccaggaa
    24481 gagtgccagg tagaactcga agcccggttc gagtccgtgc tgctgggacg agtacggggg
    24541 cagggtccgg ggcatcccag cacaaggatg actttgcgca acctggtcca cggctcgctt
    24601 cacggggtca cgagcgcggg cggcacaccg gccgcgctac ccgtcggggt cgggccggac
    24661 ggcgtgcgcc tcgacggcga ccatgtcgac gcggagatcg acttgcaggg gtacgcgatc
    24721 gacctgcagg aggcccgcgt gagcgcgttc ggccccgacg atccccggac gatgctggct
    24781 accgcctacc tcgcctacgc cctggcgctt ggagaccatc tggacggtca agtggaagca
    24841 gcggcgtacc tggcacaaga cgcctacgac ggcctggccg actgccacga cgacggcgcg
    24901 gaacatgtga cagccgacga cgtcgaaaca gtccggcaga tcgttgagtg gatcaaggag
    24961 aaggtcgagt acgccgacgg ttgaccagat cggccagttc ggcgcggacc tgatccgcct
    25021 tcgccgcccc gacggactca agcagcccga gcgcggtctc gaagtgccgt tcggccgact
    25081 gatcgtggcc tcgggaaaca gctacctggc caaggcccca gtgcgcgagg ccttcctcat
    25141 actcgctacc gcac
//
