GCF_900052895.1 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_FIXU01000001.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	RiPP-like	2,451	15,754

NZ_FIXU01000003.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 3.1	lanthipeptide-class-ii	1	21,487

NZ_FIXU01000005.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 5.1	T3PKS	1	21,720

NZ_FIXU01000011.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 11.1	RiPP-like	10,924	21,220

NZ_FIXU01000013.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 13.1	RiPP-like	33,747	51,604

NZ_FIXU01000014.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 14.1	terpene-precursor	16,558	37,433

NZ_FIXU01000027.1 (Streptococcus pneumoniae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 27.1	RiPP-like	17,401	27,327

Region	Type	From	To	Most similar known cluster
Region 1.1	RiPP-like	2,451	15,754
Region 3.1	lanthipeptide-class-ii	1	21,487
Region 5.1	T3PKS	1	21,720
Region 11.1	RiPP-like	10,924	21,220
Region 13.1	RiPP-like	33,747	51,604
Region 14.1	terpene-precursor	16,558	37,433
Region 27.1	RiPP-like	17,401	27,327

No secondary metabolite regions were found in these records:: NZ_FIXU01000002.1 (Streptococcus pneumoniae); NZ_FIXU01000004.1 (Streptococcus pneumoniae); NZ_FIXU01000006.1 (Streptococcus pneumoniae); NZ_FIXU01000007.1 (Streptococcus pneumoniae); NZ_FIXU01000008.1 (Streptococcus pneumoniae); NZ_FIXU01000009.1 (Streptococcus pneumoniae); NZ_FIXU01000010.1 (Streptococcus pneumoniae); NZ_FIXU01000012.1 (Streptococcus pneumoniae); NZ_FIXU01000015.1 (Streptococcus pneumoniae); NZ_FIXU01000016.1 (Streptococcus pneumoniae); NZ_FIXU01000017.1 (Streptococcus pneumoniae); NZ_FIXU01000018.1 (Streptococcus pneumoniae); NZ_FIXU01000019.1 (Streptococcus pneumoniae); NZ_FIXU01000020.1 (Streptococcus pneumoniae); NZ_FIXU01000021.1 (Streptococcus pneumoniae); NZ_FIXU01000022.1 (Streptococcus pneumoniae); NZ_FIXU01000023.1 (Streptococcus pneumoniae); NZ_FIXU01000024.1 (Streptococcus pneumoniae); NZ_FIXU01000025.1 (Streptococcus pneumoniae); NZ_FIXU01000026.1 (Streptococcus pneumoniae); NZ_FIXU01000028.1 (Streptococcus pneumoniae); NZ_FIXU01000029.1 (Streptococcus pneumoniae); NZ_FIXU01000030.1 (Streptococcus pneumoniae); NZ_FIXU01000031.1 (Streptococcus pneumoniae); NZ_FIXU01000032.1 (Streptococcus pneumoniae); NZ_FIXU01000033.1 (Streptococcus pneumoniae); NZ_FIXU01000034.1 (Streptococcus pneumoniae); NZ_FIXU01000035.1 (Streptococcus pneumoniae); NZ_FIXU01000036.1 (Streptococcus pneumoniae); NZ_FIXU01000037.1 (Streptococcus pneumoniae); NZ_FIXU01000038.1 (Streptococcus pneumoniae); NZ_FIXU01000039.1 (Streptococcus pneumoniae); NZ_FIXU01000040.1 (Streptococcus pneumoniae)

Compact view

NZ_FIXU01000001.1 - Region 1 - RiPP-like

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Location: 2,451 - 15,754 nt. (total: 13,304 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001388.3	0.53	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000619.3	0.52	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.52	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0000624.3	0.51	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.50	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002577.2	0.48	ribosomal	lactococcin G	Lactococcus lactis
BGC0001229.4	0.43	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001862.4	0.41	ribosomal	pallidocin	Aeribacillus pallidus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001388.3	0.53	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000619.3	0.52	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.52	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0000624.3	0.51	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.50	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002577.2	0.48	ribosomal	lactococcin G	Lactococcus lactis
BGC0001229.4	0.43	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001862.4	0.41	ribosomal	pallidocin	Aeribacillus pallidus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.71 out of 26.06

Confidence: medium

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 18.42 out of 19.52

Confidence: strong

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 20.08 out of 24.78

Confidence: medium

Additional weak hits (1):

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.85 out of 32.93

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AfsQ1	Two-component system AfsQ1-Q2, activator of antibiotic production
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes

NZ_FIXU01000003.1 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 21,487 nt. (total: 21,487 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

A1M11_RS01735: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

A1M11_RS11665: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	0.56	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.55	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3	0.55	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000525.5	0.54	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0001210.5	0.52	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001311.5	0.51	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0000532.3	0.51	ribosomal	mutacin II	Streptococcus mutans
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	0.56	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0002110.3	0.55	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3	0.55	ribosomal	thusin	Bacillus thuringiensis serovar rongseni
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000525.5	0.54	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0001210.5	0.52	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001311.5	0.51	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0000532.3	0.51	ribosomal	mutacin II	Streptococcus mutans
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for A1M11_RS01735

A1M11_RS01730

Leader:

MNNKFTGKINELELEQLVGDNQVVGG

Core:

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

Core with dehydrations:

IDhbPDhbIIPADhbIDhaFVGVDhbFDhbVDhbLNAGACysPDhbDhaGCysDhbKDhaCysNK

antiSMASH-DB 4.0 matches for A1M11_RS01730

100.0%

NZ_CKMQ01000043.1and 8 others:

NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS09950_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptideNZ_LR216041.1 Lanthipeptides: E0F00_RS05470_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide

Lanthipeptides: AE832_RS09950_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

94.6%

NZ_PNGD01000001.1and 1 other:

NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide

Lanthipeptides: CJ239_RS00165_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

ITPTII ATISF GVTFTVTLNAGACPTSGCTKSCNK

1

ITPTIIAATISFAGVTFTVTLNAGACPTSGCTKSCNK

37

63.2%

NZ_CP017953.1and 15 others:

NZ_CP017953.1 Lanthipeptides: BAMY_RS16390_lanthipeptideNZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptideNZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptideNZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptideNZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptideNZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptideNZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptideNZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptideNZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptideNZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptideNZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptideNZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptideNZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptideNZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptideNZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide

Lanthipeptides: BAMY_RS16390_lanthipeptide

2

TPTII-PATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

TPT++ ATI G TFTVTL+A +CPTS CTK CNK

2

TPTVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK

38

with 83 more sequence matches

Only the first 10 are displayed here.

53.8%

NZ_CP033054.1and 11 others:

NZ_CP033054.1 Lanthipeptides: D9777_RS18840_lanthipeptideNZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptideNZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptideNZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptideNZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptideNZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptideNZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptideNZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptideNZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptideNZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptideNZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide

Lanthipeptides: D9777_RS18840_lanthipeptide

5

IIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

++ ATI G TFTVTL+A +CPTS CTK CNK

7

VLTATIGLTGTTFTVTLSAASCPTSACTKQCNK

39

51.3%

NZ_WHOM01000078.1and 1 other:

NZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29290_lanthipeptide

Lanthipeptides: GCN81_RS29290_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

ITPTI+PAT VG + + G CPTSGCTK C

8

ITPTILPATGVIVGASAALQ---GGCPTSGCTKRC

39

45.9%

NZ_CP047645.1and 7 others:

NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide

Lanthipeptides: GSN02_RS17435_lanthipeptide

11

SFVGVTFTVTLNAGACPTSGCTKSCNK

37

+ G TFTVTL+A +CPTS CT CNK

10

ALTGTTFTVTLSAASCPTSACTNLCNK

36

45.9%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

I+ T+ AT V FTVT S CTKSCNK

4

ISATVASATA--VSALFTVT--------SACTKSCNK

30

42.9%

NZ_BMRY01000003.1and 19 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12360_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide

Lanthipeptides: IE140_RS12360_lanthipeptide

2

TPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

TPTIIPAT + G CPTSGCTK C

9

TPTIIPATAVTTVIVGASAAMQGGCPTSGCTKRC

42

42.9%

NZ_BMSZ01000006.1and 4 others:

NZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12790_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18195_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide

Lanthipeptides: IE135_RS12790_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

ITPTI+PAT + G CPTSGCTK C

8

ITPTIVPATAVTTVIVGASAAMQGGCPTSGCTKRC

42

40.5%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide

Lanthipeptides: PO853_RS06520_lanthipeptide

2

TPTI-IPATISFVGVTFTVTLNAGACPTSGCTKSC

35

TPTI IP +I+ G ++ CPTS CT++C

2

TPTITIPISIAVSGW-----ISDKTCPTSVCTRAC

31

40.5%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

+ P PAT + +G T VT A CPT+ CT C

3

VNPETTPATPTIIGATIAVT--ASLCPTTKCTSRC

35

39.5%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

ITPTIIPATIS-FVGVTFTVTLNAGACPTSGCTKSC

35

+ P PAT S + +T VT++A CPT+ CT C

3

VNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

37.8%

NZ_CM000756.1and 17 others:

NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide

Lanthipeptides: BTHUR0011_RS14765_lanthipeptide

7

PATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

PA ++ + VT + CPTS C+KSCNK

8

PAIVTAISAVTAVTAQS-PCPTSACSKSCNK

37

MIBiG 4.0 matches for A1M11_RS01730

21.6%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

19

VTLNAGACPTSGCTKSC

35

V ++A CPT+ CT C

21

VGVSAAFCPTTKCTSRC

37

16.2%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

26

CPTSGCTKSC

35

CPT+ CT C

17

CPTTKCTSKC

26

A1M11_RS11670

Leader:

MAQKDFPQKINSQLLEEISDNSAVGA

Core:

GWAQLSFISEALGNKGAVCTGTIECQNNCR

Core with dehydrations:

GWAQLDhaFIDhaEALGNKGAVCysDhbGDhbIECysQNNCysR

antiSMASH-DB 4.0 matches for A1M11_RS11670

100.0%

NZ_CKMQ01000043.1and 10 others:

NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS11585_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_LR216041.1 Lanthipeptides: E0F00_RS05465_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide

Lanthipeptides: AE832_RS11585_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

GWAQLSFISEALGNKGAVCTGTIECQNNCR

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

60.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

GW LS ++LGNKG VCT T ECQ CR

2

GWKDLS---KSLGNKGYVCTLTKECQKLCR

28

53.3%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

+S LGNKGA CT T+ECQNNC

6

VSCRLGNKGAWCTLTVECQNNC

27

with 100 more sequence matches

Only the first 10 are displayed here.

53.3%

NZ_FOBE01000018.1:

Lanthipeptides: BMW61_RS13085_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNC

29

GW S +S ALGN+G+ CT T ECQ C

1

GW--YSEMSAALGNRGSYCTLTKECQACC

27

50.0%

NZ_CP006058.1and 23 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGNKGA CT T+ECQ++C

6

ISCKLGNKGAWCTLTVECQSSC

27

50.0%

NZ_CP061033.1and 1 other:

NZ_CP061033.1 Lanthipeptides: IAU67_RS09320_lanthipeptide

Lanthipeptides: IAU67_RS09320_lanthipeptide

9

SEALGNKGAVCTGTIECQNNCR

30

S ALGN+G CTGTIECQ C+

1

SWALGNEGNFCTGTIECQKTCQ

22

46.7%

NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

IS LGNKG CT T ECQ +C+

6

ISCQLGNKGQWCTLTKECQRSCK

28

46.7%

NZ_BJTV01000004.1and 1 other:

NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide

Lanthipeptides: TNCT1_RS10200_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S+ALGN G CT T ECQ NC

8

LSDALGNHGGWCTLTKECQANCN

30

46.7%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S+ALGN G CT T ECQ NC

8

LSDALGNSGGWCTLTKECQPNCN

30

46.7%

NZ_CP016795.1and 5 others:

NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide

Lanthipeptides: BC342_RS18360_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

+S+ALGN G CT T ECQ NC

8

LSDALGNHGGWCTLTKECQPNC

29

46.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGN G CT T ECQ NC

6

ISCHLGNTGRFCTLTKECQPNC

27

46.7%

NZ_KE384107.1:

Lanthipeptides: G586_RS23925_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNC

29

GW + +S +LGN+G+ CT T ECQ C

1

GW--YADLSASLGNRGSYCTITKECQACC

27

44.7%

NZ_CM000756.1and 7 others:

NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide

Lanthipeptides: BTHUR0011_RS34475_lanthipeptide

7

FISEALGNKGAVCTGTIECQNNCR

30

ISE GNKG VCT T+EC NNCR

14

IISETFGNKGKVCTYTVECVNNCR

37

MIBiG 4.0 matches for A1M11_RS11670

46.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGNKGA CT T+EC +C

6

ISCRLGNKGAYCTLTVECMPSC

27

46.7%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S ALGN G CT T ECQ NC

8

LSNALGNNGGWCTLTKECQPNCN

30

18.9%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

11

ALGNKGAVCTGTIECQNNC

29

A+G A C T +C + C

20

AVGVSAAFCP-TTKCTSRC

37

with 1 more sequence matches

17.9%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

19

CTGTIECQNNC

29

CT + ECQ NC

28

CTLSKECQPNC

38

allorf_015235_015399

Leader:

MCHTGNFLKSLFGL

Core:

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

Core with dehydrations:

CysEFRHCysDHNDhbQKIIDhaPANQNLPVLDhbANDKIDhbWWLRPQDhbPR

antiSMASH-DB 4.0 matches for allorf_015235_015399

100.0%

NZ_CKMQ01000043.1and 5 others:

NZ_CKMQ01000043.1 Lanthipeptides: allorf_11887_12051_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: allorf_046172_046336_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: allorf_046172_046336_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: allorf_015235_015399_lanthipeptideNZ_LR216041.1 Lanthipeptides: allorf_0995261_0995425_lanthipeptide

Lanthipeptides: allorf_11887_12051_lanthipeptide

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

38.9%

NZ_AP023392.1and 3 others:

NZ_CP015557.1 Lanthipeptides: allorf_0952604_0952840_lanthipeptideNZ_CP100430.1 Lanthipeptides: allorf_0940325_0940561_lanthipeptideNZ_JAEUXF010000003.1 Lanthipeptides: allorf_111883_112119_lanthipeptide

Lanthipeptides: allorf_0989669_0989905_lanthipeptide

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

CE +C HN K N NL +A+DK TWWLRPQTP+

2

CELSYCAHNNLKSNRQLNPNLTGWSADDKKTWWLRPQTPK

41

37.5%

NZ_MRXY01000010.1:

Lanthipeptides: allorf_005966_006160_lanthipeptide

1

CEFRHCDHNTQKIISPANQNL

21

CE R+C HN KIISPA+QNL

2

CELRYCVHNIPKIISPADQNL

22

with 3 more sequence matches

27.5%

NZ_CP065430.1:

Lanthipeptides: allorf_1209205_1209336_lanthipeptide

1

CEFRHCDHNTQKIISPAN

18

CE R+C HN KIIS A+

2

CELRYCVHNIPKIISSAD

19

22.5%

NZ_CAKMMP010000011.1:

Lanthipeptides: allorf_230038_230169_lanthipeptide

4

RHCDHNTQKIISPANQNLPVLTANDKITW

32

RHC + +NL L N +I W

2

RHC-RQAAFFVKMLEKNLRKLFTNTRIVW

29

10.0%

NZ_JAAXRC010000001.1:

Lanthipeptides: allorf_596278_596487_lanthipeptide

8

HNTQKIISPANQNLPVLTANDKITWWLRP

36

H + I+ ++P + +++ +W RP

24

HLYARTITETTWSIPGVRTHERYPYWTRP

52

MIBiG 4.0 matches for allorf_015235_015399

10.0%

BGC0000503.5 (cinA):

Lanthipeptide: cinnamycin

6

CDHNTQ

11

CD NT+

14

CDGNTK

19

Lanthipeptide(s) for A1M11_RS11665

A1M11_RS01730

Leader:

MNNKFTGKINELELEQLVGDNQVVGG

Core:

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

Core with dehydrations:

IDhbPDhbIIPADhbIDhaFVGVDhbFDhbVDhbLNAGACysPDhbDhaGCysDhbKDhaCysNK

antiSMASH-DB 4.0 matches for A1M11_RS01730

100.0%

NZ_CKMQ01000043.1and 8 others:

NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS09950_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptideNZ_LR216041.1 Lanthipeptides: E0F00_RS05470_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide

Lanthipeptides: AE832_RS09950_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

94.6%

NZ_PNGD01000001.1and 1 other:

NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide

Lanthipeptides: CJ239_RS00165_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

ITPTII ATISF GVTFTVTLNAGACPTSGCTKSCNK

1

ITPTIIAATISFAGVTFTVTLNAGACPTSGCTKSCNK

37

63.2%

NZ_CP017953.1and 15 others:

NZ_CP017953.1 Lanthipeptides: BAMY_RS16390_lanthipeptideNZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptideNZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptideNZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptideNZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptideNZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptideNZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptideNZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptideNZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptideNZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptideNZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptideNZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptideNZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptideNZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptideNZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide

Lanthipeptides: BAMY_RS16390_lanthipeptide

2

TPTII-PATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

TPT++ ATI G TFTVTL+A +CPTS CTK CNK

2

TPTVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK

38

with 83 more sequence matches

Only the first 10 are displayed here.

53.8%

NZ_CP033054.1and 11 others:

NZ_CP033054.1 Lanthipeptides: D9777_RS18840_lanthipeptideNZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptideNZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptideNZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptideNZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptideNZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptideNZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptideNZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptideNZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptideNZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptideNZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide

Lanthipeptides: D9777_RS18840_lanthipeptide

5

IIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

++ ATI G TFTVTL+A +CPTS CTK CNK

7

VLTATIGLTGTTFTVTLSAASCPTSACTKQCNK

39

51.3%

NZ_WHOM01000078.1and 1 other:

NZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29290_lanthipeptide

Lanthipeptides: GCN81_RS29290_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

ITPTI+PAT VG + + G CPTSGCTK C

8

ITPTILPATGVIVGASAALQ---GGCPTSGCTKRC

39

45.9%

NZ_CP047645.1and 7 others:

NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide

Lanthipeptides: GSN02_RS17435_lanthipeptide

11

SFVGVTFTVTLNAGACPTSGCTKSCNK

37

+ G TFTVTL+A +CPTS CT CNK

10

ALTGTTFTVTLSAASCPTSACTNLCNK

36

45.9%

NZ_CP086141.1and 1 other:

NZ_CP086141.1 Lanthipeptides: LL065_RS24780_lanthipeptide

Lanthipeptides: LL065_RS24780_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

I+ T+ AT V FTVT S CTKSCNK

4

ISATVASATA--VSALFTVT--------SACTKSCNK

30

42.9%

NZ_BMRY01000003.1and 19 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12360_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide

Lanthipeptides: IE140_RS12360_lanthipeptide

2

TPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

TPTIIPAT + G CPTSGCTK C

9

TPTIIPATAVTTVIVGASAAMQGGCPTSGCTKRC

42

42.9%

NZ_BMSZ01000006.1and 4 others:

NZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12790_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18195_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide

Lanthipeptides: IE135_RS12790_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

ITPTI+PAT + G CPTSGCTK C

8

ITPTIVPATAVTTVIVGASAAMQGGCPTSGCTKRC

42

40.5%

NZ_AP026714.1and 21 others:

NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptideNZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide

Lanthipeptides: PO853_RS06520_lanthipeptide

2

TPTI-IPATISFVGVTFTVTLNAGACPTSGCTKSC

35

TPTI IP +I+ G ++ CPTS CT++C

2

TPTITIPISIAVSGW-----ISDKTCPTSVCTRAC

31

40.5%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSC

35

+ P PAT + +G T VT A CPT+ CT C

3

VNPETTPATPTIIGATIAVT--ASLCPTTKCTSRC

35

39.5%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

ITPTIIPATIS-FVGVTFTVTLNAGACPTSGCTKSC

35

+ P PAT S + +T VT++A CPT+ CT C

3

VNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

37.8%

NZ_CM000756.1and 17 others:

NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptideNZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide

Lanthipeptides: BTHUR0011_RS14765_lanthipeptide

7

PATISFVGVTFTVTLNAGACPTSGCTKSCNK

37

PA ++ + VT + CPTS C+KSCNK

8

PAIVTAISAVTAVTAQS-PCPTSACSKSCNK

37

MIBiG 4.0 matches for A1M11_RS01730

21.6%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

19

VTLNAGACPTSGCTKSC

35

V ++A CPT+ CT C

21

VGVSAAFCPTTKCTSRC

37

16.2%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

26

CPTSGCTKSC

35

CPT+ CT C

17

CPTTKCTSKC

26

A1M11_RS11670

Leader:

MAQKDFPQKINSQLLEEISDNSAVGA

Core:

GWAQLSFISEALGNKGAVCTGTIECQNNCR

Core with dehydrations:

GWAQLDhaFIDhaEALGNKGAVCysDhbGDhbIECysQNNCysR

antiSMASH-DB 4.0 matches for A1M11_RS11670

100.0%

NZ_CKMQ01000043.1and 10 others:

NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS11585_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptideNZ_LR216041.1 Lanthipeptides: E0F00_RS05465_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptideNZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide

Lanthipeptides: AE832_RS11585_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

GWAQLSFISEALGNKGAVCTGTIECQNNCR

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

60.0%

NZ_LR134483.1and 1 other:

NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide

Lanthipeptides: EL241_RS01725_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNCR

30

GW LS ++LGNKG VCT T ECQ CR

2

GWKDLS---KSLGNKGYVCTLTKECQKLCR

28

53.3%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

+S LGNKGA CT T+ECQNNC

6

VSCRLGNKGAWCTLTVECQNNC

27

with 100 more sequence matches

Only the first 10 are displayed here.

53.3%

NZ_FOBE01000018.1:

Lanthipeptides: BMW61_RS13085_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNC

29

GW S +S ALGN+G+ CT T ECQ C

1

GW--YSEMSAALGNRGSYCTLTKECQACC

27

50.0%

NZ_CP006058.1and 23 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGNKGA CT T+ECQ++C

6

ISCKLGNKGAWCTLTVECQSSC

27

50.0%

NZ_CP061033.1and 1 other:

NZ_CP061033.1 Lanthipeptides: IAU67_RS09320_lanthipeptide

Lanthipeptides: IAU67_RS09320_lanthipeptide

9

SEALGNKGAVCTGTIECQNNCR

30

S ALGN+G CTGTIECQ C+

1

SWALGNEGNFCTGTIECQKTCQ

22

46.7%

NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

IS LGNKG CT T ECQ +C+

6

ISCQLGNKGQWCTLTKECQRSCK

28

46.7%

NZ_BJTV01000004.1and 1 other:

NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide

Lanthipeptides: TNCT1_RS10200_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S+ALGN G CT T ECQ NC

8

LSDALGNHGGWCTLTKECQANCN

30

46.7%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S+ALGN G CT T ECQ NC

8

LSDALGNSGGWCTLTKECQPNCN

30

46.7%

NZ_CP016795.1and 5 others:

NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptideNZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide

Lanthipeptides: BC342_RS18360_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

+S+ALGN G CT T ECQ NC

8

LSDALGNHGGWCTLTKECQPNC

29

46.7%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGN G CT T ECQ NC

6

ISCHLGNTGRFCTLTKECQPNC

27

46.7%

NZ_KE384107.1:

Lanthipeptides: G586_RS23925_lanthipeptide

1

GWAQLSFISEALGNKGAVCTGTIECQNNC

29

GW + +S +LGN+G+ CT T ECQ C

1

GW--YADLSASLGNRGSYCTITKECQACC

27

44.7%

NZ_CM000756.1and 7 others:

NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptideNZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptideNZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptideNZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide

Lanthipeptides: BTHUR0011_RS34475_lanthipeptide

7

FISEALGNKGAVCTGTIECQNNCR

30

ISE GNKG VCT T+EC NNCR

14

IISETFGNKGKVCTYTVECVNNCR

37

MIBiG 4.0 matches for A1M11_RS11670

46.7%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

8

ISEALGNKGAVCTGTIECQNNC

29

IS LGNKGA CT T+EC +C

6

ISCRLGNKGAYCTLTVECMPSC

27

46.7%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

8

ISEALGNKGAVCTGTIECQNNCR

30

+S ALGN G CT T ECQ NC

8

LSNALGNNGGWCTLTKECQPNCN

30

18.9%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

11

ALGNKGAVCTGTIECQNNC

29

A+G A C T +C + C

20

AVGVSAAFCP-TTKCTSRC

37

with 1 more sequence matches

17.9%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

19

CTGTIECQNNC

29

CT + ECQ NC

28

CTLSKECQPNC

38

allorf_015235_015399

Leader:

MCHTGNFLKSLFGL

Core:

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

Core with dehydrations:

CysEFRHCysDHNDhbQKIIDhaPANQNLPVLDhbANDKIDhbWWLRPQDhbPR

antiSMASH-DB 4.0 matches for allorf_015235_015399

100.0%

NZ_CKMQ01000043.1and 5 others:

NZ_CKMQ01000043.1 Lanthipeptides: allorf_11887_12051_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: allorf_046172_046336_lanthipeptideNZ_CKMR01000002.1 Lanthipeptides: allorf_046172_046336_lanthipeptideNZ_FIXU01000003.1 Lanthipeptides: allorf_015235_015399_lanthipeptideNZ_LR216041.1 Lanthipeptides: allorf_0995261_0995425_lanthipeptide

Lanthipeptides: allorf_11887_12051_lanthipeptide

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

38.9%

NZ_AP023392.1and 3 others:

NZ_CP015557.1 Lanthipeptides: allorf_0952604_0952840_lanthipeptideNZ_CP100430.1 Lanthipeptides: allorf_0940325_0940561_lanthipeptideNZ_JAEUXF010000003.1 Lanthipeptides: allorf_111883_112119_lanthipeptide

Lanthipeptides: allorf_0989669_0989905_lanthipeptide

1

CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR

40

CE +C HN K N NL +A+DK TWWLRPQTP+

2

CELSYCAHNNLKSNRQLNPNLTGWSADDKKTWWLRPQTPK

41

37.5%

NZ_MRXY01000010.1:

Lanthipeptides: allorf_005966_006160_lanthipeptide

1

CEFRHCDHNTQKIISPANQNL

21

CE R+C HN KIISPA+QNL

2

CELRYCVHNIPKIISPADQNL

22

with 3 more sequence matches

27.5%

NZ_CP065430.1:

Lanthipeptides: allorf_1209205_1209336_lanthipeptide

1

CEFRHCDHNTQKIISPAN

18

CE R+C HN KIIS A+

2

CELRYCVHNIPKIISSAD

19

22.5%

NZ_CAKMMP010000011.1:

Lanthipeptides: allorf_230038_230169_lanthipeptide

4

RHCDHNTQKIISPANQNLPVLTANDKITW

32

RHC + +NL L N +I W

2

RHC-RQAAFFVKMLEKNLRKLFTNTRIVW

29

10.0%

NZ_JAAXRC010000001.1:

Lanthipeptides: allorf_596278_596487_lanthipeptide

8

HNTQKIISPANQNLPVLTANDKITWWLRP

36

H + I+ ++P + +++ +W RP

24

HLYARTITETTWSIPGVRTHERYPYWTRP

52

MIBiG 4.0 matches for allorf_015235_015399

10.0%

BGC0000503.5 (cinA):

Lanthipeptide: cinnamycin

6

CDHNTQ

11

CD NT+

14

CDGNTK

19

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.38 out of 27.78

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.81 out of 20.97

Confidence: medium

Additional weak hits (4):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.03 out of 30.22

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 25.62 out of 36.54

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.08 out of 29.65

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 21.85 out of 30.98

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

A1M11_RS01730 - Class II

Cleavage pHMM score: -1.00

RODEO score: 0

Monoisotopic mass: 3514.9 Da

Molecular weight: 3517.1 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3535.1 Da N = 1; 3553.1 Da N = 2; 3571.2 Da N = 3; 3589.2 Da N = 4; 3607.2 Da N = 5; 3625.2 Da N = 6; 3643.2 Da N = 7; 3661.3 Da N = 8

A1M11_RS11670 - Class II

Cleavage pHMM score: -5.50

RODEO score: 0

Monoisotopic mass: 3097.5 Da

Molecular weight: 3099.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3117.5 Da N = 1

allorf_015235_015399 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 4650.4 Da

Molecular weight: 4653.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4671.3 Da N = 1; 4689.3 Da N = 2; 4707.3 Da N = 3

A1M11_RS01730 - Class II

Cleavage pHMM score: -1.00

RODEO score: 0

Monoisotopic mass: 3514.9 Da

Molecular weight: 3517.1 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3535.1 Da N = 1; 3553.1 Da N = 2; 3571.2 Da N = 3; 3589.2 Da N = 4; 3607.2 Da N = 5; 3625.2 Da N = 6; 3643.2 Da N = 7; 3661.3 Da N = 8

A1M11_RS11670 - Class II

Cleavage pHMM score: -5.50

RODEO score: 0

Monoisotopic mass: 3097.5 Da

Molecular weight: 3099.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3117.5 Da N = 1

allorf_015235_015399 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 4650.4 Da

Molecular weight: 4653.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4671.3 Da N = 1; 4689.3 Da N = 2; 4707.3 Da N = 3

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria

NZ_FIXU01000005.1 - Region 1 - T3PKS

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Location: 1 - 21,720 nt. (total: 21,720 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

additional biosynthetic genes

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binding site

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Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: reductase

A1M11_RS03145: hydroxymethylglutaryl-CoA reductase

smcogs: SMCOG1187: hydroxymethylglutaryl-CoA reductase

Transferases: phosphotransferase

A1M11_RS03165: Glucose-specific phosphotransferase enzyme IIA

smcogs: SMCOG1145: Glucose-specific phosphotransferase enzyme IIA

Ligases: synthase

A1M11_RS03140: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000486.4	0.41	ribosomal	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000519.4	0.41	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000616.4	0.40	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0000592.5	0.40	ribosomal	microviridin B	Microcystis aeruginosa NIES-298
BGC0000205.3	0.40	PKS	bryostatin	Candidatus Endobugula sertula
BGC0001743.3	0.39	ribosomal	plantaricyclin	Lactobacillus plantarum
BGC0001928.2	0.39	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000486.4	0.41	ribosomal	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000519.4	0.41	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000616.4	0.40	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0000592.5	0.40	ribosomal	microviridin B	Microcystis aeruginosa NIES-298
BGC0000205.3	0.40	PKS	bryostatin	Candidatus Endobugula sertula
BGC0001743.3	0.39	ribosomal	plantaricyclin	Lactobacillus plantarum
BGC0001928.2	0.39	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.40 out of 30.25

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.76 out of 27.78

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.14 out of 20.97

Confidence: strong

Additional weak hits (1):

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.25 out of 30.97

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator

NZ_FIXU01000011.1 - Region 1 - RiPP-like

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Location: 10,924 - 21,220 nt. (total: 10,297 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0001638.4	0.40	ribosomal	klebsazolicin	Klebsiella pneumoniae subsp. ozaenae
BGC0000571.3	0.36	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000513.3	0.36	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000551.5	0.36	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000504.5	0.36	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002698.2	0.35	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000501.3	0.35	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000500.5	0.35	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0001638.4	0.40	ribosomal	klebsazolicin	Klebsiella pneumoniae subsp. ozaenae
BGC0000571.3	0.36	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000513.3	0.36	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000551.5	0.36	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000504.5	0.36	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002698.2	0.35	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000501.3	0.35	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000500.5	0.35	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

Additional weak hits (1):

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.05 out of 28.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ToxT	Regulator of MSHA biosynthesis

NZ_FIXU01000013.1 - Region 1 - RiPP-like

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Location: 33,747 - 51,604 nt. (total: 17,858 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: aminotransferase

A1M11_RS07235: aminotransferase

smcogs: SMCOG1019: aminotransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002577.2	0.56	ribosomal	lactococcin G	Lactococcus lactis
BGC0000624.3	0.55	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0000619.3	0.50	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.50	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0001388.3	0.50	ribosomal	gassericin E	Lactobacillus gasseri
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000558.5	0.48	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002005.2	0.46	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0001229.4	0.43	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002577.2	0.56	ribosomal	lactococcin G	Lactococcus lactis
BGC0000624.3	0.55	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0000619.3	0.50	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.50	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0001388.3	0.50	ribosomal	gassericin E	Lactobacillus gasseri
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000558.5	0.48	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002005.2	0.46	ribosomal	RaxX	Xanthomonas oryzae pv. oryzae
BGC0001229.4	0.43	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.09 out of 26.06

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.13 out of 20.97

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 24.43 out of 24.78

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.31 out of 26.06

Confidence: medium

Additional weak hits (2):

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.98 out of 29.25

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes

NZ_FIXU01000014.1 - Region 1 - terpene-precursor

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Location: 16,558 - 37,433 nt. (total: 20,876 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: back translocase

A1M11_RS07425: GTP-binding protein LepA

smcogs: SMCOG1190: GTP-binding protein LepA

Ligases: synthetase

A1M11_RS07450: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000648.3	0.31	terpene	carotenoid	Myxococcus xanthus
BGC0001456.3	0.30	terpene	isorenieratene	Streptomyces argillaceus
BGC0001756.3	0.28	terpene	retigeranin, arathanatriene	Arabidopsis thaliana
BGC0001594.3	0.27	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0001595.3	0.26	other (other)	fischerindole	Fischerella sp. SAG 46.79
BGC0000668.5	0.26	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000648.3	0.31	terpene	carotenoid	Myxococcus xanthus
BGC0001456.3	0.30	terpene	isorenieratene	Streptomyces argillaceus
BGC0001756.3	0.28	terpene	retigeranin, arathanatriene	Arabidopsis thaliana
BGC0001594.3	0.27	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0001595.3	0.26	other (other)	fischerindole	Fischerella sp. SAG 46.79
BGC0000668.5	0.26	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

A1M11_RS07450: PT_FPPS_like

Domain 1 (27 - 272): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.39 out of 27.78

Confidence: medium

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.19 out of 23.79

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.20 out of 24.78

Confidence: medium

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 17.68 out of 19.52

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.35 out of 26.06

Confidence: medium

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
AfsQ1	Two-component system AfsQ1-Q2, activator of antibiotic production
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
IolR	Regulator of the inositol catabolism
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes

NZ_FIXU01000027.1 - Region 1 - RiPP-like

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Location: 17,401 - 27,327 nt. (total: 9,927 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: hydrolase

A1M11_RS10575: HAD-superfamily hydrolase, subfamily IA, variant

smcogs: SMCOG1115: HAD-superfamily hydrolase, subfamily IA, variant

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000504.5	0.41	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001638.4	0.40	ribosomal	klebsazolicin	Klebsiella pneumoniae subsp. ozaenae
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0000500.5	0.40	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0002049.3	0.40	ribosomal	microviridin N9, microviridin N8, microviridin N7, microviridin N6, microviridin N5, microviridin N4, microviridin N3	Nostoc punctiforme PCC 73102
BGC0001576.3	0.39	ribosomal	divamide A	Prochloron didemni
BGC0001887.3	0.39	ribosomal	huazacin	Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0002111.3	0.39	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000504.5	0.41	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001638.4	0.40	ribosomal	klebsazolicin	Klebsiella pneumoniae subsp. ozaenae
BGC0001639.3	0.40	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0000500.5	0.40	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0002049.3	0.40	ribosomal	microviridin N9, microviridin N8, microviridin N7, microviridin N6, microviridin N5, microviridin N4, microviridin N3	Nostoc punctiforme PCC 73102
BGC0001576.3	0.39	ribosomal	divamide A	Prochloron didemni
BGC0001887.3	0.39	ribosomal	huazacin	Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0002111.3	0.39	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.39 out of 27.78

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.64 out of 26.06

Confidence: medium

Additional weak hits (3):

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 26.23 out of 31.73

Confidence: weak

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.44 out of 39.62

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 24.79 out of 33.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
MogR	Repressor of flagellar motility genes