LOCUS       NZ_FIXU01000003        21487 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptococcus pneumoniae strain B18210a, whole genome shotgun
            sequence.
ACCESSION   NZ_FIXU01000003
VERSION     NZ_FIXU01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900052895.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 02:58:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,298
            CDSs (total)                      :: 2,246
            Genes (coding)                    :: 2,088
            CDSs (with protein)               :: 2,088
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 62 of 158
            Pseudo Genes (incomplete)         :: 91 of 158
            Pseudo Genes (internal stop)      :: 44 of 158
            Pseudo Genes (multiple problems)  :: 32 of 158
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21487
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FIXU01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21487
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..21487
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21487
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5132:11487](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5133..11487)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(<1..643)
                     /locus_tag="A1M11_RS11660"
                     /pseudo=""
     CDS             complement(<1..643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /locus_tag="A1M11_RS11660"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIDL
                     LDCNQTTIWRNVKNMRSSDSTLSFKKHVVVVTMHI"
     misc_feature    891..905
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.38"
                     /tool="antismash"
     gene            985..2331
                     /gene="gdhA"
                     /locus_tag="A1M11_RS01700"
                     /old_locus_tag="ERS050419_00331"
     CDS             985..2331
                     /EC_number="1.4.1.4"
                     /GO_function="GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /locus_tag="A1M11_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00331"
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="WP_000199568.1"
                     /transl_table=11
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHPE
                     YIEENILARITEPERVVSFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTVNQ
                     GILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIGPSL
                     DVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVYYTEE
                     MLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGIDFDLLV
                     DVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKRLVAQGV
                     ICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLSWTREEVD
                     GRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     misc_feature    1007..1022
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.08"
                     /tool="antismash"
     gene            complement(2827..2997)
                     /locus_tag="A1M11_RS01705"
                     /old_locus_tag="ERS050419_00332"
     CDS             complement(2827..2997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /locus_tag="A1M11_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00332"
                     /product="hypothetical protein"
                     /protein_id="WP_000711943.1"
                     /transl_table=11
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIVL
                     GSLIVYKNNKN"
     gene            complement(3040..5133)
                     /locus_tag="A1M11_RS01710"
                     /old_locus_tag="ERS050419_00333"
     CDS             complement(3040..5133)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /locus_tag="A1M11_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00333"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_078169235.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.5e-34, bitscore:
                     111.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKGR
                     DGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKVYI
                     MDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGRLIL
                     TLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARSMGIL
                     FSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVGGVVDI
                     GTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLIYSVETE
                     ALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLFAPIIILI
                     FGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVNDIWLENEE
                     NVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQSGSGKSTLS
                     KILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTS
                     QKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRITLARALINNPSIVILDE
                     ATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMD
                     LGG"
     gene            complement(5133..7937)
                     /locus_tag="A1M11_RS11665"
                     /old_locus_tag="ERS050419_00334"
     CDS             complement(5133..7937)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000215516.1"
                     /locus_tag="A1M11_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00334"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_000215516.1"
                     /sec_met_domain="DUF4135 (E-value: 3.6e-78, bitscore:
                     256.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.3e-42, bitscore:
                     136.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESYLNKIEKSITSGTIEENYESTFYTFNNQFSKYFINSLSKD
                     IRRYLSEGSIEMLEKQFYSEIYYLTIRTLIDDFYNWQRVNESVPKEERYHRYCLKLGTV
                     PFFKKIKKAYPVLFIKIFHLHQHTINLIEEAMLSIIRDKDEIKERIGFNFDDGIKEIVL
                     STGDRHNGGKTAVIFKNNNDDKILYKPHSLNNDVFLENFFSLVNRSLPLKLYHPKSISK
                     KNYGWQEFIEFQECNLDNDYEDYFYRYGELLAIAYALQVTDLHKENIIMSKNYPIVIDS
                     ETLFTNPDLSCNRNSTIQNPETVHDLFQKFIKDSVLDTLLLPNNFQSSLFDFDLSPLTN
                     YQQLSENITRFTIENDFSHNIHLKEVHVVLPSSNVKKETNKFYGKIIDGFKACYTILEN
                     SKNYFIEEIKLLSEKYPLYLRQVLRPTMVYVKFLEASTHPDYLTDIKKQRKLFQKLNSS
                     LYKLDSTLGKQVEIEINSLMKGDVPYFYTKFNSLSIYSMENKICNFYATSIQSKLLERF
                     QKLGNKDMLKQLHVIFLSLSTVKDTTFSDINQSPLHDFIIPVNDENSLVLKVGDYVNHQ
                     VVWNNNNEFCILPSVSQIDDKKVILPVSYCLYDGGGVVLLLYYLYLKFNEEKYKIVADG
                     LLKGFESMIEIETNRNFSAFNGIGSVIYIYYCLFILTSEPDYHEKYKFYLAMLEKQDIP
                     LDQPIDFLGISSLIILLCNIYKIEHSSKLFTLLKKCINYCISQLDNITVTGLAHGYSGV
                     AMSLSYYYEINPSTDILKCIEELLYKEDKFFNNILKNWKDIRRNHNDSFPNFWCYGAPG
                     ILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHGSVGTISCLDAILKDEENLL
                     IKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYEISRKQDDRLLNVLLLE
                     LKRT"
     gene            complement(7998..8189)
                     /locus_tag="A1M11_RS01730"
                     /old_locus_tag="ERS050419_00335"
     CDS             complement(7998..8189)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="A1M11_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00335"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_001060181.1"
                     /transl_table=11
                     /translation="MNNKFTGKINELELEQLVGDNQVVGGITPTIIPATISFVGVTFTV
                     TLNAGACPTSGCTKSCNK"
     CDS_motif       complement(8112..8189)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNNKFTGKINELELEQLVGDNQVVGG"
                     /locus_tag="A1M11_RS01730_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7998..8111)
                     /prepeptide="core"
                     /locus_tag="A1M11_RS01730_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.00"
                     /molecular_weight="3517.1"
                     /monoisotopic_mass="3514.9"
                     /core_sequence="ITPTIIPATISFVGVTFTVTLNAGACPTSGCTKSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNKFTGKINELELEQLVGDNQVVGG"
                     /leader_location="[8111:8189](-)"
                     /alternative_weights="3535.1"
                     /alternative_weights="3553.1"
                     /alternative_weights="3571.2"
                     /alternative_weights="3589.2"
                     /alternative_weights="3607.2"
                     /alternative_weights="3625.2"
                     /alternative_weights="3643.2"
                     /alternative_weights="3661.3"
     gene            complement(8212..8382)
                     /locus_tag="A1M11_RS11670"
                     /old_locus_tag="ERS050419_00336"
     CDS             complement(8212..8382)
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057443.1"
                     /locus_tag="A1M11_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00336"
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="WP_000057443.1"
                     /sec_met_domain="mature_ha (E-value: 1.8e-10, bitscore:
                     33.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKDFPQKINSQLLEEISDNSAVGAGWAQLSFISEALGNKGAVC
                     TGTIECQNNCR"
     CDS_motif       complement(8305..8382)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAQKDFPQKINSQLLEEISDNSAVGA"
                     /locus_tag="A1M11_RS11670_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8212..8304)
                     /prepeptide="core"
                     /locus_tag="A1M11_RS11670_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="3099.5"
                     /monoisotopic_mass="3097.5"
                     /core_sequence="GWAQLSFISEALGNKGAVCTGTIECQNNCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAQKDFPQKINSQLLEEISDNSAVGA"
                     /leader_location="[8304:8382](-)"
                     /alternative_weights="3117.5"
     gene            complement(8452..11487)
                     /locus_tag="A1M11_RS01735"
                     /old_locus_tag="ERS050419_00337"
     CDS             complement(8452..11487)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655315.1"
                     /locus_tag="A1M11_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00337"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_061747015.1"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-95, bitscore:
                     311.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.2e-64, bitscore:
                     209.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDSMINYWLNYFPEYSLETFEKELTKHLGENYIEKLLNFYKDYE
                     TVDVDIIFKYVSLNLEAIPKQFKEIIEEKYLFSSIIIPFISKYFSEFSYTISRNKSIED
                     SDEFLTYSVLDVADRINTLLYRSIIGDISTLKARGVLQGKTSVNRMDYYKNKYIKEEKN
                     LVDFYAKFSELTRLTSYVVKNTFEFYLEIIQQFQEQYVKILELFQCKTDSKVLISKIEL
                     GNGDSHKKNKSVSKIFLSSGNTIIYKPRSLNIEKSFEKMMEFLRDQNAILDYKLPNIIS
                     TEKYGFCEYIDTEECMNDLDVKGFYQRIGELLGILYSLNSVDFHYENIIAKGAYPVPID
                     LETLIHPQIVDRNNDLSAFKKASKKFESSVITTGLLPIFLKGNEVGGVSMNSEQISTFK
                     TDYIKDTNSDNIHIEREYYVISPKNNNPIINGKIVDAKDYIFEIIKGFQGIYKWIMNNR
                     KIYIEKIYELFSNTVGRFIPRATLYYSQLLRISLSPEFTQKHFERKMLLRRLYIGSENS
                     ETMLIDSEFKDLLEADIPYFSFIIGDNKIFDSKGVEVKGVNLTNFKEDFNSKISTFCDE
                     DLKEQIGYIKDSFISRKNQSDSNDIKFQTYYNKLKPELWLSTATKIGDLIIDNSIEGVN
                     EYGRKDLAWISVTMQGFEEDVWLPSVLTNDLYSGNAGISLFLINLWNITGKKRFLEYAK
                     KSVETSKVLLGNKYIHSNHLVGAFTGVGGMIYSLAEIAHLTGDVKNKNFIKKSILSLDE
                     LILRDTSNDLISGNTGLLAVILKLVNSDSYYNTPDIKYVISKIVQKILHESKFVDGLRF
                     WECMPNRNYVGFSHGNAGIHSYLFKAMKYLGDSRAEEILQESLNYEKKCFSSHKNDWYK
                     SKDEKQISYTWCHGSPGILLSKLLLLSSGYNFDNLDNDIRLSIENTKAYGFGNNPTYCH
                     GDLGNLEILNYASKLLHKKNLNNLCTNIYQELFDTVLVKEWDKKNLKSSNTYGLMVGLS
                     GWGYSMLSNYTDHSLNNFLWLD"
     gene            complement(11554..11625)
                     /gene="shp3"
                     /locus_tag="A1M11_RS12585"
     CDS             complement(11554..11625)
                     /codon_start=1
                     /gene="shp3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /locus_tag="A1M11_RS12585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide pheromone SHP3"
                     /protein_id="WP_001812431.1"
                     /transl_table=11
                     /translation="MKKISKFLPILVLVMDIIIIVGG"
     gene            11705..12559
                     /locus_tag="A1M11_RS01740"
                     /old_locus_tag="ERS050419_00338"
     CDS             11705..12559
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /locus_tag="A1M11_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00338"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_000837495.1"
                     /sec_met_domain="TIGR01716 (E-value: 2.5e-66, bitscore:
                     216.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEISC
                     IRLINILDKLHITLDEFLVLYNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDTSD
                     YTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRTINY
                     NSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIKTLLD
                     NELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDHFNKLV
                     NKK"
     gene            complement(12604..14469)
                     /locus_tag="A1M11_RS01745"
                     /old_locus_tag="ERS050419_00339"
     CDS             complement(12604..14469)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /locus_tag="A1M11_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00339"
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="WP_061747016.1"
                     /transl_table=11
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLDF
                     PSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHHLIQSFSPEDNLTPEEINRIG
                     YEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMISDRI
                     SKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLHVQID
                     FSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKSVYSLE
                     ELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYFEDREVR
                     DIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTDNQIEKLV
                     DDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNKENMDNNCF
                     IKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEIKDELVLEIA
                     EIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTESIMLDRLNTYI
                     LKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENALLE"
     gene            complement(14456..14821)
                     /gene="mobC"
                     /locus_tag="A1M11_RS01750"
                     /old_locus_tag="ERS050419_00340"
     CDS             complement(14456..14821)
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /locus_tag="A1M11_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00340"
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_000263049.1"
                     /transl_table=11
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLNP
                     NMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKEVD
                     KEFQVEVKRLKEFHGSH"
     gene            complement(14831..15190)
                     /locus_tag="A1M11_RS01755"
                     /old_locus_tag="ERS050419_00341"
     CDS             complement(14831..15190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /locus_tag="A1M11_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00341"
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="WP_061747017.1"
                     /transl_table=11
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILMT
                     DDKQLAAKEWFSLWQSQKFEQFSRDVHLVLIIARENHQVTQEHVSILLTCVQELIAEVN
                     QVQSLSRGFREKYMR"
     CDS             15235..15399
                     /gene="allorf_015235_015399"
                     /locus_tag="allorf_015235_015399"
                     /protein_id="allorf_015235_015399"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MCHTGNFLKSLFGLCEFRHCDHNTQKIISPANQNLPVLTANDKIT
                     WWLRPQTPR"
     CDS_motif       15235..15276
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCHTGNFLKSLFGL"
                     /locus_tag="allorf_015235_015399_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15277..15399
                     /prepeptide="core"
                     /locus_tag="allorf_015235_015399_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="4653.2"
                     /monoisotopic_mass="4650.4"
                     /core_sequence="CEFRHCDHNTQKIISPANQNLPVLTANDKITWWLRPQTPR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCHTGNFLKSLFGL"
                     /leader_location="[15234:15276](+)"
                     /alternative_weights="4671.3"
                     /alternative_weights="4689.3"
                     /alternative_weights="4707.3"
     misc_feature    complement(15266..15281)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            complement(16009..16881)
                     /locus_tag="A1M11_RS13340"
                     /old_locus_tag="ERS050419_00343"
     CDS             complement(16009..16881)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1M11_RS13340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS050419_00343"
                     /product="hypothetical protein"
                     /protein_id="WP_001812430.1"
                     /transl_table=11
                     /translation="MLAEAIIKNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIH
                     PHILHGVEISAADKLHIVCIYDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQK
                     IVNYIAHFNSYDILKKGSHLSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGV
                     LSLGQKVVAMLDFLLAYSDYSKDFRPLIIDRPEDNLDNRYIYRHLVQQFRDVKAQRQII
                     LATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKM
                     SIYETALSE"
     gene            complement(16875..17165)
                     /locus_tag="A1M11_RS13345"
                     /old_locus_tag="ERS050419_00344"
     CDS             complement(16875..17165)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1M11_RS13345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS050419_00344"
                     /product="hypothetical protein"
                     /protein_id="WP_001213954.1"
                     /transl_table=11
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFSN
                     WTATKYRKITEDELYDIFFENKKIKVDKTIFLVILIRLFFLVQKNILVFLC"
     gene            complement(17193..17954)
                     /gene="pezT"
                     /locus_tag="A1M11_RS01780"
                     /old_locus_tag="ERS050419_00345"
     CDS             complement(17193..17954)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="pezT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /locus_tag="A1M11_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00345"
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="WP_000405362.1"
                     /transl_table=11
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAGK
                     TTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLVTK
                     LSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEELYI
                     INPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTTSAAD
                     VLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(17954..18430)
                     /gene="pezA"
                     /locus_tag="A1M11_RS01785"
                     /old_locus_tag="ERS050419_00346"
     CDS             complement(17954..18430)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="pezA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /locus_tag="A1M11_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00346"
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="WP_000579608.1"
                     /transl_table=11
                     /translation="MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTEL
                     IDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISI
                     DDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(18875..19330)
                     /locus_tag="A1M11_RS13350"
                     /pseudo=""
     CDS             complement(18875..19330)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /locus_tag="A1M11_RS13350"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNL"
     gene            complement(19605..21344)
                     /locus_tag="A1M11_RS01800"
                     /old_locus_tag="ERS050419_00349"
                     /pseudo=""
     CDS             complement(19605..21344)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /locus_tag="A1M11_RS01800"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00349"
                     /product="glycoside hydrolase family 13 protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDPF
                     IFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGCVE
                     NSLENLHAIGNGFKLP"
     misc_feature    21380..21391
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.81"
                     /tool="antismash"
     misc_feature    complement(21400..21418)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.62"
                     /tool="antismash"
     misc_feature    21419..21435
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.85"
                     /tool="antismash"
ORIGIN
        1 gaaattctcg tatatagtga ctatggacat gtggacctac tcctattgga gaccaacaag
       61 atcccagtct actgattcta ccgaaaccag cctcatcttg gtacatcaag cgaaccttac
      121 gaaaacgtct actggtttta aagcgctttc ttttcttctt gaattgagat tttattttta
      181 gacgcgacaa tggtttgagc gtctgctttc ttaggatgtt ctggacgtgg cataatattt
      241 cgccaaccat ggcgcttcaa cagttgatag aaggcatcac gtgtgtagga acgacctaac
      301 tcctttttat aagcctgaaa taaggcatca attgtaacaa attctcctgc ctctgcagcc
      361 ttcaaatgac gggcaagaaa ggctttctct tccccaaccg tcatatatgc atggttacga
      421 ccaccacgtg tttcttgaag gagagagtcg agtccgaact cctcatattt tttacatttc
      481 gccaaatcgt tgtttgatta cagtctaaaa gatctataat ctctttataa gatttgccca
      541 tcagacgaaa tagaacgatt tgaaggcgtt tatgatattt agctgtacga gagtctttta
      601 aaagtgtttt gatggtttgg atttcttctt tagttgattt catattacta ttgtataatg
      661 ctttttgatt ttagtctggt ataaatattg ctttcctcca aaatggtcat aattttacta
      721 gcaaatctaa catatcacgg ataaattaac aagtgatttc tgaattgcta aacattttct
      781 tttcttatag cataccatac tttaagattt tgtctttgag aaagatattt ccaagaaaaa
      841 cgttcgtttt tttatctatt ttcaaaaaaa ccaaaaaact gaattgaaag aatttttaga
      901 aaatttctgt tttttcttta cagtgaaaaa aaattctgct ataatgtctt atgtaataaa
      961 atatgacaat aaaaggagaa cgatatgaca tctgctaaag aatatatcca aagcgtgttt
     1021 gaaactgtga aagctcgtaa cgggcacgag gctgaattcc tccaagctgt tgaagaattt
     1081 ttcaacactt tagaacctgt atttgaaaaa caccctgagt atatcgaaga aaatatcttg
     1141 gcacgtatta ctgagcctga gcgcgtggtt tctttccgtg ttccttgggt tgaccgtgat
     1201 ggaaaagttc aagtaaaccg cggttaccgt gttcaattca actcagctgt tggaccatac
     1261 aaaggcggac ttcgtttcca cccaactgta aaccaaggga tcttgaaatt cctcggattt
     1321 gaacaaatct ttaaaaatgt cttgactgga cttcctatcg gtggaggtaa aggtggatca
     1381 gacttcgatc ctaaaggtaa aacagatgct gaagtgatgc gcttctgcca aagcttcatg
     1441 actgaattgc aaaaacacat cggaccatca cttgacgtac ctgctggtga tatcggtgtt
     1501 ggtggacgtg aaattggtta cctttacggt caatacaaac gtcttaacca atttgatgct
     1561 ggtgtcttga ctggtaaacc tcttggattt ggtgggagct tgattcgtcc agaagcaact
     1621 ggttacggtt tggtttacta tactgaagaa atgctcaaag ctaacggtaa cagctttgct
     1681 ggtaagaaag tcgttatttc aggttctggt aacgttgctc aatatgctct tcaaaaagca
     1741 actgaactcg gtgcaactgt tatttctgtt tctgactcaa atggttatgt catcgatgaa
     1801 aatggtatcg acttcgatct tttggttgat gttaaagaaa aacgtcgtgc tcgtttgact
     1861 gagtatgcag ctgaaaaagc aactgcaacc taccacgaag gtactgtatg gacttacgct
     1921 ggaaactatg acattgctct tccatgtgcc actcaaaacg aaatcaacgg tgaagcagct
     1981 aaacgtttgg ttgctcaagg cgttatctgt gtatctgaag gtgccaacat gccgagcgac
     2041 cttgatgcca tcaaagttta caaagaaaat ggtatcttct acggacctgc aaaagctgcc
     2101 aacgctggtg gtgtagccgt ttcagctctt gaaatgagcc aaaacagtct tcgcctctca
     2161 tggactcgtg aagaagttga tggccgtctc aaagacatca tgacaaacat cttcaacaca
     2221 gctaaaacga cttcagaaac atacggtctt gataaagact accttgcagg agctaacatt
     2281 gctgcctttg aaaatgtagc aaacgctatg attgcccaag gtattgttta agatttattt
     2341 gcttaatcct caatcactac gattggggat ttttagttga gttagacagt tgggaaattc
     2401 taattaaatg aaataaaaac tgaacaaatt gattgcggaa ttcaaaccaa tttctaacat
     2461 atttctagaa attaatttga cttttctaat cgatttgttc atatcttatt tcaatttact
     2521 atacttactt aacccttttt atactcaatg aaaatcaaag agcaaactag gaagcgagcc
     2581 gcaggctgta cttgagtacg gcaaggcaaa gctgacgtgg tttgaagaga ttttcaaaga
     2641 gtattaaaca aaaagaaaaa ccgctactcc taagaatagc gatttaatca tgtttttaag
     2701 ctactactgt agttgctcta ttatttaagt gttatgaata acttcaatat ctttaaagct
     2761 ttttgttaga tttataattt caactatagc catctctact ccttagttta cagcaaaaaa
     2821 ttatgcttaa ttcttattgt ttttgtaaac aatcagcgaa cccaatacta ttccattcaa
     2881 caagcctaaa gaaataccat attcaactgg aaaatctaaa aaaattgcaa acactattcc
     2941 aatcatcacc cctagtgagg ctgttgttaa aattacatat tcattttctt tcttcatttt
     3001 ctttacacct catttccttg ttgtatataa gctgtagtac tatccaccaa gatccattaa
     3061 gtacttatga tttcctgact caacaatctt accacctttc attacaaaaa taatatccgc
     3121 atccttaatc gttgacaatc tatgagctat aattatttga gtacaaccct gactttgtat
     3181 atactttgtt attctttcct cattaatagt gtctaatgca ctagttgctt catctaaaat
     3241 tacaatacta ggattattta ttaatgcacg tgccagtgtt atccgttgcc tttgcccacc
     3301 tgaaatattt gaccccatct ctgagatgat agtattaaat ttcatcggca tagccatgat
     3361 ttcatcatag atttgaactg ctttacaaac ttcctctatc ttttgtgaag taacttcgtt
     3421 ctttaaagtt atattatcaa gaatacttcg gttcaataaa aatgaatcct gtggaactac
     3481 tcctaaattt tgacttaata tttttttatc tatttgatta atatttacac catcaaataa
     3541 aatttttcct gtatcaatct tatataatcc tgatagtatt tttgataacg tactttttcc
     3601 tgaccccgat tgaccgacta gtgcaattct ctgtcctggc tcaatagtca aatttaaatt
     3661 ttctattaca ggagctgagt ctttggaata agagaaagat aggtccttaa tatctattct
     3721 accttctaaa gaacactttt taagaccatt ttcaacattc tcttcatttt caagccagat
     3781 atcatttact ctatttaagt atcctgctgc caaaatatac tgcgtataag cattaaatat
     3841 tgagatttct gaactaaata aaattgatgc catggtttga aatgcgacaa cctcacccaa
     3901 taaaattttt ccatttaaaa cattatcaag tccaaaaatc aatataatta taggagcgaa
     3961 caattgaaat acattagtag ctgaattgta taaaatatgc acaatacttc gttttttata
     4021 ctttgtcaat acgtttttta aatacttaga ccagttttca tatatttcat cttctaatcc
     4081 cgatattttt attgaagaaa tagtatttaa tgcttctgtt tctactgagt aaatcaatga
     4141 ttgttcttgt aattctctat taaccgtatc atacattatt tttctagtac taaacagaaa
     4201 caaaaaattg attaaactca atataagagc tataattgat aatgtttttg aactaagaaa
     4261 catatatatt acaacactta gaatagtccc gatatctact actcccccaa caacttggtt
     4321 agtaaatagc tccctaaaac cactaagact agaaattctg tataaaatat ctccttttgc
     4381 cctgagttca aaaaaactat atggtagttt aagcaaatgc ttaaatgtaa aactttcaat
     4441 atctctacta aaaaatatat tagaaaatag aattcccata ctcctagcca agatagaaat
     4501 aagatacaaa caaagtagag aaaataaaat taaaaacgag gtttgaaaag aaaatgtatt
     4561 ccctaatgca gaattaataa actttgaagt cattactggt acggaaagta ttattaagta
     4621 acttattatt gaaaatagta acgtcaaaat caatcgacct tttacctttg aaaaactaga
     4681 gaatactctt atccatggag aaggaaactg cgacttcaaa gattgataat tttcgttagg
     4741 aaatgatagc agtactatat tactaaaatg ttttgaaaac tccttaaact cataatttat
     4801 atatccttta gaaggatcca ttatatagac cttattcttt tttactttgt aaataactac
     4861 ataatgttga ttatcccaga atgctattaa tggtaacgga agttcactaa ttttatttac
     4921 atctttaact tgatatgagc cagtatcaaa atttcgttta ttcaataact gtttcaagtc
     4981 acctatacta taaccatctc tccctttttc tatatcacgt cttaaatcta gtaatgtctc
     5041 tttgctttta tagaaatgta gtatggacaa gcagcaacat aaaccacatt ctatttgaga
     5101 catttgctca atattaggta cttttctagt catcatgtcc tctttaactc cagtaataaa
     5161 acattaagta atctatcatc ttgttttcga gatatttcat agacaactcc agatactccc
     5221 agcataaaag aaaatgtatt catagtattc aaatccgtac ttaattctgg tttgataacc
     5281 tgagaaacga cattatcaaa ataaaaatct atagattctt ttattaatag gttttcttca
     5341 tctttcaata ttgcatcaag acaactgata gtacctacag aaccgtgaca taaattcaat
     5401 tctcttattt tttctacatt agttaataca ttttcaatta ttgataaatc attattccca
     5461 atattagttt tatcgaaaat ttcttttcta gctaataaaa tgcccggagc tccataacac
     5521 caaaaattag gaaaggaatc attatgattt cttcttatgt ctttccaatt ttttaatata
     5581 ttattgaaaa atttatcttc tttatatagt aattcctcta tacattttaa tatatctgta
     5641 ctaggattaa tttcataata atatgataat gacattgcta ctccagaata accgtgtgct
     5701 aaacctgtta ctgttatatt atctaattgt gaaatacaat aattaataca cttttttaat
     5761 agtgtaaaaa gttttgagct atgttctatc ttataaatat tacacaataa aataattaaa
     5821 ctggatattc ctaaaaaatc aattggttga tctaacggaa tatcttgttt ttctagcatt
     5881 gctaagtaaa acttatattt ttcatgatag tctggttccg atgttagtat aaaaaggcaa
     5941 taatatatat atattactga tccaatgcca ttaaacgccg aaaagtttct atttgtttca
     6001 atttcaatca ttgactcgaa cccctttagt aaaccatccg caactatctt atacttttct
     6061 tcgttgaatt ttaaatatag ataatataat agtaaaacta ctccaccacc atcatacagg
     6121 caataagaaa ctggtaaaat aactttctta tcatcaatct gactaacaga aggaagtatg
     6181 caaaactcat tattattatt ccaaacgact tgatgattaa catagtcgcc gacctttaat
     6241 actagagaat tttcgtcatt aacaggaata ataaaatcgt gtaatgggct ttgatttatg
     6301 tcagagaaag tcgtatcttt aactgtcgat aaagataaaa aaatcacatg caactgcttt
     6361 aacatatcct tatttcccag tttttgaaat ctttcaagta gtttactttg gatagatgta
     6421 gcataaaaat tacaaatttt attttccata gaataaatac tcagactatt aaattttgta
     6481 taaaagtacg gtacatctcc tttcattaaa ctattaattt caatttctac ttgcttgcct
     6541 aaagtactgt ctaatttata taacgagcta ttaagttttt gaaatagctt tctctgtttt
     6601 ttgatatccg taaggtaatc tgggtgggtt gaagcttcta aaaacttaac atataccata
     6661 gttggtctta gaacctgtct cagatataga ggatattttt ctgacaataa ttttatttct
     6721 tcaataaaat aattcttact attttcaagt atagtataac aagctttgaa tccatcaatt
     6781 atcttaccat aaaatttatt agtttctttt ttgacattac tactcggaag tactacatgt
     6841 acttctttta aatgaatatt atgtgaaaaa tcattttcta ttgtaaatct agtaatattt
     6901 tcagataatt gttgataatt agtcagcgga cttaaatcaa aatcaaataa agagctttga
     6961 aaattatttg gtaacaataa tgtgtctaaa actgagtctt tgataaactt ttgaaataaa
     7021 tcatgtacag tttcagggtt ttgaatagtt gaattcctgt tgcagcttaa gtctggattt
     7081 gtaaataaag tctcagaatc aataacaatc ggataattct tactcattat tatgttttct
     7141 ttatggagat ctgtcacttg cagtgcataa gctattgcaa gaagttcacc atatctataa
     7201 aagtaatctt cgtaatcatt atcaagatta cattcttgaa actctataaa ctcctgccat
     7261 ccataatttt tttttgaaat tgatttagga tggtataatt ttaaaggtaa acttctatta
     7321 actaaactaa aaaaattctc caaaaatacg tcattattta atgaatgagg cttatataaa
     7381 attttatcat cattattatt tttaaatata actgcagtct ttcccccgtt atgcctatca
     7441 ccagtagaaa gtacaatttc tttgattcca tcatcaaaat tgaatcctat acgctcctta
     7501 atttcatctt tatctctaat gattgataac attgcttctt ctattaaatt aatcgtatgt
     7561 tgatgcaaat gaaaaatttt aataaataag actgggtatg ctttcttaat ttttttaaaa
     7621 aaaggaaccg tccctaattt taaacagtat ctatgatatc tttcttcttt cggtacactc
     7681 tcattaactc tttgccaatt gtaaaaatca tcaatcaaag tacgaattgt caaataatat
     7741 atctcagaat aaaattgttt ttctagcatc tctatagatc cttctgaaag ataacgtcgt
     7801 atatctttcg ataaagagtt aataaagtac tttgaaaatt gattattaaa agtataaaat
     7861 gtactttcat aattttcctc tatagtacct gaagtaattg atttttcaat tttatttaaa
     7921 taactttcaa ctgtcataat tatctcctat tcaaaagcat tatactgggc tatatcgtca
     7981 aaaatgttgt tacttaatta tttattgcaa ctctttgtac atccggaagt tggacatgca
     8041 ccagcattta atgttacggt aaatgtaaca cccacaaaag aaattgtagc gggaataata
     8101 gtaggggtta ttccacctac aacttgatta tctccaacta attgttcgag ttctaattca
     8161 ttaatttttc ctgtaaattt attattcatt atttttctcc actaaatatt attatctaca
     8221 attattttga cattcaattg tacctgtgca aactgcacct ttatttccaa gagcttcact
     8281 tataaaacta agctgcgccc atcccgctcc aactgcactg ttatcactaa tttcttctaa
     8341 taactgactg ttaatttttt gaggaaaatc tttttgtgcc atctaactat tctctcctaa
     8401 ctaattttaa tttatatagc ccagaataat gcttttgaaa aaagagacgt atcaatctaa
     8461 ccatagaaag ttattcaaag agtgatccgt ataatttgat aacatggagt aaccccaccc
     8521 cgataaacca accattagac cgtatgtatt cgaagatttt aaattttttt tatcccattc
     8581 tttaacaaga acagtatcaa atagttcctg atatatattt gtacataaat tatttagatt
     8641 ctttttatga agtagtttag aagcataatt taatatttct aaatttccta aatcaccgtg
     8701 acaatatgta ggattattcc caaatccata agctttagtg ttctcaatac ttagtctaat
     8761 gtcattatct aaattatcaa aattatatcc tgaagaaagc aataataatt tacttaaaag
     8821 tatcccaggt gatccatgac accacgtata agatatttgt ttttcatctt tagatttata
     8881 ccaatcattt ttatgagaag agaagcattt tttttcatag ttcaatgatt cttgcaaaat
     8941 ttcctctgca cgactatctc ccaaatattt cattgcctta aataaataag aatggatacc
     9001 tgcatttccg tgagaaaaac caacataatt tctatttggc atacattccc aaaaccttaa
     9061 cccgtctaca aactttgatt catgtaatat tttttgaact attttggaaa taacatattt
     9121 aatatcaggt gtgttgtaat atgaatctga attaacaagt tttaaaatta cagccaatag
     9181 ccctgtattc ccactaatta aatcatttga agtatccctt aaaattagtt catctaaact
     9241 taagatagat tttttaataa aatttttatt ttttacatct ccagtgagat gagcaatttc
     9301 agcaagtgaa tatatcatcc ctcctacacc tgtaaaagcc cctactaaat gattagagtg
     9361 aatgtactta tttcccaata atacctttga ggtttcaaca gatttcttgg catactctaa
     9421 aaatcttttc ttacctgtta tgttccataa attgattaaa aataacgaaa ttcctgcatt
     9481 cccactatac aaatcatttg ttaaaacaga aggtaaccaa acatcctctt caaaaccctg
     9541 cattgttaca ctaatccagg ccaaatcttt tcgaccgtac tcattaactc cttcaattga
     9601 attatcaata atcaaatctc caattttagt agcagtagac aaccataatt ctggttttaa
     9661 tttattataa tatgtttgaa atttaatgtc attgctgtca gattgatttt ttctacttat
     9721 aaaagaatcc ttgatatagc caatctgttc ttttaaatct tcatcacaaa aagtagagat
     9781 cttactgtta aaatcttctt taaaattggt taaatttacg ccttttactt ctaccccttt
     9841 agaatcaaat attttattat caccgataat aaaagaaaaa taaggaatat ctgcttctag
     9901 taaatcttta aattctgaat caatcaacat tgtctcagaa ttttcgcttc ctatatataa
     9961 tcttctaagt aacatctttc tctcaaaatg cttctgagta aattctgggc ttagtgatat
    10021 ccttaacaat tgtgaatagt ataaagtagc ccttggtata aatcttccaa ctgtgttact
    10081 aaaaagctca tatatttttt caatatatat ctttctatta ttcataatcc atttatatat
    10141 accttgaaat ccttttataa tttcaaaaat atagtctttg gcatctacaa tcttaccatt
    10201 gataatagga ttgttgtttt taggagaaat gacataatac tctctctcaa tatgaatatt
    10261 atcgctgtta gtatccttga tatagtcagt tttaaaggtt gatatttgct cactattcat
    10321 actaacacca ccaacttcat ttccttttaa aaaaatgggt aaaagccctg tagttattac
    10381 tgagctttca aattttttag aagctttttt gaatgctgat aaatcattat ttctatccac
    10441 tatctgagga tggattaatg tttctaaatc aattggaact ggataagctc ctttcgcaat
    10501 aatgttttca taatgaaaat ctacagaatt caaagaataa agtattccca acaattctcc
    10561 tattctttga taaaacccct ttacatccaa atcattcata cattcttctg tatctatata
    10621 ttcacaaaat ccatattttt cagttgaaat aatattaggt agtttataat ctaaaatcgc
    10681 attttgatct cgtaagaatt ccatcatttt ttcaaacgat ttttcaatat taagcgagcg
    10741 aggcttatat attatagtgt ttccgcttga taaaaaaatt ttactcacac tcttattctt
    10801 tttatgtgaa tcaccatttc ccaattctat tttagaaatc aatactttag aatccgtttt
    10861 acactgaaat agttcaagaa ttttcacata ttgctcttga aattgttgaa taatttctaa
    10921 ataaaattca aaagtgtttt ttactacata ggaagttaaa cgtgttaact cggaaaattt
    10981 tgcatagaaa tcaactaaat ttttttcttc ttttatatat ttattcttgt aataatccat
    11041 tctgttgaca gaagtttttc cctgaagaac gcctctagct tttagagtag agatatctcc
    11101 aataattgaa cgatacagca aagtgttgat tctatccgca acatccaata cagagtaagt
    11161 taaaaattca tccgaatctt caatgctctt atttctggaa atggtataag aaaactcaga
    11221 aaaatatttg ctaataaacg gtataataat tgaagaaaat aaatattttt cttcaattat
    11281 ttctttaaat tgttttggaa tagcctctaa atttaaacta acgtacttaa atataatatc
    11341 tacatccaca gtctcgtaat ctttatagaa atttaaaagt ttctcgatat aattctctcc
    11401 taaatgcttt gttaactcct tttcaaacgt ttctaaacta tactccggaa aataatttaa
    11461 ccaataatta atcatactat ctttcatcgt atcctccaac cagtactaag tctttagatg
    11521 atatctaaag acttaggtgt acacctaagc atcttaccca ccaacaatga tgataatatc
    11581 catcaccaaa accaaaatcg gtaaaaattt tgaaattttc ttcatacttg gacttccttt
    11641 ccgtttttat ttattgtaca ataaataaaa acggatttaa tttttgttgg gaaaatggga
    11701 aattatgaaa tcaaaacttg gcatcacact tagaaaagtt cgtaaaggaa aacaaattag
    11761 tctatgctct gtagcagatg aacatctttc aaaatcacaa atatctcgtt ttgaacgtgg
    11821 ggagtcagag atatcttgta ttcgactaat caatatttta gacaaattac atattacttt
    11881 ggatgagttc cttgttttat acaatgacga ctataccagt tccgaatcat ttgctaatct
    11941 agtacagtac attcgtaagc aatattcatc acaaagtatc aataatatag catgtctact
    12001 ttctgatact tctgattaca ctctaaattc ttttgagaaa acaatggtaa aatctatttt
    12061 acacacaatg gattcgaaca tcattccatc agatgaagag cttcttcatc tgacagacta
    12121 tcttttcaaa gttgaaaaat ggggctatta tgaaatcatt ttattaggta actgtgtacg
    12181 cacaattaac tacaactcct acttcttatt aactaaagag atgttaaata actatattta
    12241 ctcatctctg aataaaacta ataagcagat tgtctctcag cttgctatta attgcttcat
    12301 tctaagcatt gataaggaag aattttctaa ttgctcctat ttaattagta agataaagac
    12361 attgttggac aatgaactaa acttttatga acaaacagtt tttctctatg caactggtta
    12421 ctttgaattt aaacgttgcc aatcaaccag tggaattgaa aaaatgaaac aagccataca
    12481 agtcttcgat attttaggag aagataagtt aaaattacac tatactgacc attttaataa
    12541 actagtaaat aaaaaataaa tgaaattatt ctctatcttt taactaatta gtcgtaaata
    12601 atattattct agtaaggcat tctcgtgaaa ttttagaact gtaaatttat tggtattaat
    12661 aattttcaca aacaaatcca atcttctagc tatctcctca tatttattaa tttcattacc
    12721 aagttcctgt tgtaatttta aaatatacgt attgagtcga tctaacatta ttgattccgt
    12781 catgttcatt tggtcaaaat catacttagc taattttcta gtctcatgat cttcactctt
    12841 caaattgata aggacttccg ccatcttgtt taaggtggcg attttttctt gggtttcttc
    12901 tagctgcata tcaatctctg caatttctaa tacaagctca tctttgattt cttggtattg
    12961 tttgttcgtg ttagatagtt caatcataag attaatttca gaaatcttct ctttaagact
    13021 ttttaaagtt ggtcgtctat aggggagttt ttggctatcg ttgctcaatt gtctgattaa
    13081 ggtcctaccc ttgatgaaac aattattatc catgttttct ttattataga caaagtaaga
    13141 agacgtttct cgaatgtaga ctttatattt tttatgattg tcttcctcaa aaatatctag
    13201 ctggtagtta ggaataaaga tgagtccact ctgtttgata ccaaacgaaa cctgtatata
    13261 gacaccatca tcaaccaact tctctatctg attatccgta agttcaatct caaactcatg
    13321 gatagcatct cgtttttcct tgtatttctt gaaggcttcc tcgatttctt cagcggagac
    13381 tttctcctta tgctgctcct ctcgaaaagt ctgaaaatct tcctgaagat tttctaatgc
    13441 ttgaatatct ctaacttctc tatcttcaaa ataacgatta aaaaattgaa catcgtacaa
    13501 tttcttatcg ctaatttttt tatgactcag gcttatcttt ttgccatctt cttctagggt
    13561 aaacatcaca tttttctgtt ttaactcgat ggttagattc aactctttag cctttacatg
    13621 caattcttct aatgaataaa cagactttag taaaaatttt aaacgacttt caatctcttg
    13681 tttggcaaaa tatgttttaa aaaagtcttc atcatataaa tctcgtttgc tgagttggcg
    13741 tcctcgaatt ggttttatca tcgttctatc tgtcatcaaa aaacggctat gcttttgact
    13801 aaaatcaatc tgaacatgca actgctttgc tttctctaaa aaatcatcaa acgatttaga
    13861 ttgctgtagc aaaaaataaa gacgttgttt caattcaaac ttatgactag attccctata
    13921 ttttttataa tctcgatagg aataacgttt ctcaataatt tttgcaccag tcactttaga
    13981 aatacggtct gaaatcatac ggaggtttcg ttccaaggca tagttccata tcaacttttt
    14041 atctgaattg cggtcaatag cgttgattag gatgtgatta tgaacatgat ctttgtctgt
    14101 gtgagttgct acgataaact taaaacgacc tcctgtcaat tccatcatga tctcataacc
    14161 aatgcggtta atttcttcag gtgtcagatt atcttcagga gaaaatgatt ggatgagatg
    14221 atgagcatga atagtttgtt ggtgtttttc ttgtcggtcg tttctggatt cgtacaactt
    14281 gtcattattg ctgaagttga cattgtacat ctctaccatt tctgcatgac tagggaagtc
    14341 caagtaattg ctcatgccaa aatcagatac taatttcaaa ttgtccgttt tatcaggatt
    14401 gaggatatac ttaattaaac gcctacgata tttttttccg tgtgtcgcaa aatgcttagt
    14461 gactaccatg aaactccttc aatcttttca cttccacttg aaattctttg tccacttcct
    14521 tgatcaactc tccgactcct ttactcaatt cttgtaattg gtcctgagaa atcagatggc
    14581 tttgattaat cgcacgcgca atttgattga tgttatttcc aatcctcctc aattcaaaca
    14641 ctaactgttc ataagtatca gtgttaatcg tgacaaatga catattggga ttaagcaaaa
    14701 cttttctggc atagactgag aaattttgac aattgctctt agcaatccgt tcattcaatt
    14761 ggtgtaattc tgaatctgtt agaaatactt ttttgagatt ggtacgataa cgataaacca
    14821 tagtagcctc ctatctcatg tatttttcac gaaacccacg actgagtgac tgtacttgat
    14881 tgacttccgc aatcaattct tgaacgcagg tcaataagat tgacacgtgt tcttgagtca
    14941 cttggtgatt ctctcttgcg ataatcaaaa ccaaatgcac atctcgactg aactgttcaa
    15001 acttttgaga ctgccaaagg gaaaaccatt ctttggcagc taactgtttg tcatcagtca
    15061 tcaaaatttt atccctgacg aatggtgaaa agtgacgata attatcaacc tccatcattt
    15121 tttcaatctg ttttagctca tctgcggtta gatttacctc ttttcgaatg tcacggtact
    15181 gttcagacat ctcttttcct cactttcatc ctttctcggg taaaccccga ccccgtgtgt
    15241 catacgggaa atttcttaaa gtccttgttc ggtctttgcg agttcaggca ttgtgatcac
    15301 aatacccaaa aaatcatatc gccagctaac caaaaccttc cagttttgac agccaacgat
    15361 aagataactt ggtggcttcg cccccaaacc cccaggtaaa attcttagtt ggatttttaa
    15421 aagttgagaa aagtatagca gaagaaattt ggggaagtta tcacaaatca agtaaggact
    15481 aatctctaac accactgcat gtaccgtcct atatttatga tcagctccca tcgtttacat
    15541 tttcaggtca ctgtcttttc ataccaggaa ttagaattga caaatttaat tagagaggta
    15601 ttcatttaat cgttcacttc ttcgctccat ttccattaca gaaatttctt caatactatg
    15661 tgttcagctg actcccatga ttcgttgtac tacgtcctaa acgctcacgg aataagccgt
    15721 acatctttcc tagtttactc tcgtaattta cgtatatagg ttacgacacc tatttggatt
    15781 ttagagttcc tcatccgcta tatatggctt caagtcgcga ttctgtttgt agaaccttga
    15841 tttcgctaat tccttcctat cccccctacc tcacgatatt caggcttagg agtcgctatt
    15901 ggtttcatct gcagcaaaca tccacagagg acttggacct cagatgtaca ctatgcctgt
    15961 cggacaaaga aaaaagtagg ctaaatttct aacctacttt ttctgactct actctgataa
    16021 agccgtctca tatatagaca ttttatgctt gaaggaatct tttcctccct ctaattgatt
    16081 gatgatatga ttttttatat atttttcact aacatatccc tgtgattcaa tccatccgtt
    16141 aactccatct gactccataa taacaacttg atctgtcata gaatttgtta caattgtagc
    16201 attatgtgtt gctaaaataa tttgacgttg agctttcaca tctctaaact gctgaactaa
    16261 atgcctgtaa atataacgat tgtctagatt gtcttcaggc cgatcaataa tcaatggtct
    16321 gaagtcttta gaataatcac tatatgctaa taaaaaatca agcatggcta caactttttg
    16381 tcccaaactt aatacaccaa cttctttata gagaatatca agttgttgcg aagattcttt
    16441 cgagttaata ttaaactcca aaaatcgtgt attttcttta gaaaaaattt ttcgtttata
    16501 tgcacctgat aagtgagaac cttttttcaa aatgtcataa ctattgaaat gagcaatata
    16561 gttaactatt ttttgattat tgaaatcctt cattatagtc agtgaatgtt gataacttcc
    16621 atctttctca cttataatat tttcacttaa ccattgatta acccatgatt cttgttcata
    16681 atcatatata catacaatat gcaatttatc tgctgcacta atttctactc catgtaaaat
    16741 atgaggatgt atatcataaa tcggataatt tttcattatg attgagactg ccatttgtaa
    16801 ctttttaata cctttggtag tattatgatc agttactaca actatttcta ttccattttt
    16861 tatgattgcc tctgctaaca taagaaaact aatatattct tttgaactag aaaaaacaac
    16921 cttatcaaaa ttactaaaaa aattgtctta tcaactttta ttttcttatt ttcaaaaaat
    16981 atatcatata gttcatcttc agtaattttt ctatatttcg ttgcagtcca attagaaaat
    17041 agcttgtaat cataagaaac aggtgtatgc aaatgaatta aagtcttgtg aaagctaccg
    17101 aatttctctt tggaatttgt tagttcttga taaacagact ttatcttgtt attaaaccct
    17161 ctcatttcta ctctcctaaa aatatcaatt gtttattttt caagtaattc attaagtctc
    17221 ttttccccca cctgcaacat ctccttctct acctgactcc actccccaaa cagtaactct
    17281 tgaagaacat ctgctgctga agttgtattt tcttttgaat catatacaca acttctatct
    17341 cgttggtaaa tttgaattct ttcaaagata gccagttctt ccaattgtcg tgtattatca
    17401 actagatgat ttacaatgaa atcatgatgt tcttttggag ttgcgcgtgc ttgatttgga
    17461 ttgataatgt acagttcttc ataacggata agagtactta gatacgacaa ttcaggcttt
    17521 gtcgcaatta aggccaattg tacttcatat cccttatttt tcaagagttg tgctgttttc
    17581 tttggaacat caactgttcg taaagttccc tctatcaaaa gattgtatct caaactactc
    17641 aattttgtta ctaaagactc taccattttt cctgcaaaat ctttggtata ttctacactg
    17701 tctttgccat attcttgctg cagttctaaa tagtgtggat gctgagaacg aaaactatca
    17761 ccatctatga taacaatatt tccttgaaat tctttctgtt taatacgatg aattgtagtc
    17821 ttaccggcac cactttgccc tccaagcaaa atcgctatag gttgcttact ggactttttt
    17881 cctcttgtca gtgaacgaag attccttgct aaagcatgtt tgaattcact atcagtataa
    17941 tcttggattt ccattaggcc accatccgtt tttcagatat ctctaacata cgttcaattc
    18001 catccaaata gccactatat ctctctattt catcaaaagt ttctactaga tagatattcg
    18061 tatgaatcaa atcagataga tcatcactca ttaaaatcca aggattagac tcatcatcaa
    18121 tgctaattcc ctgactatct tgataacgat agagtcgaga taatagatta gcacctcttt
    18181 ctttcacaat ttcaattttt aaagtcaatt cataatcttc aacaggattg agcattttat
    18241 cttctcctac aatatcgaca taagatacat taaacttctg acaaatgatg tctattaatt
    18301 cggtagagac tgaactcgtt ccattttcat aacgactcag actatttcgt gaaataccta
    18361 caatccgtgc aaattcgagt tgtgttaagt catgtgtttt acgcaaggat tttatgttct
    18421 ttccaatcat agcaaactcc tttattttta taaatccatt atagcataaa aaagcataac
    18481 gcaccaaaaa tggtgcgtta tttcttgttt ttctatccta aactttactt ctataaaagt
    18541 cacctaaaga gctataaata tttattcttg tattaatttt ttcgatgcgc aaacgatatc
    18601 tacaaataca tctataacga ttcacctttt aggattttta ttgtcaaaat tgcctttatc
    18661 tacaaagaca aaatgcttat aaaatagctt gaaatcaagg attatcacct ttttcgttgt
    18721 agcaacactc cacatgtgat tattaggcta ttagcaaagc gtatccaata cctcaataaa
    18781 gtgttgtttt tactgatatt ttaactatat tgtatagtct actatttaaa tctcaattag
    18841 gatattttat agaataccca aaattcaaca ataactaaaa gtaagattcc attgtatttc
    18901 cttgttggtt tttcatatca cgaattttat ttttcagaat attaaagtta caaatttcat
    18961 ctctaatatc gttatccgct ctgtagccat taatcatctc agtcagagtt ttccctttac
    19021 taccattctt tatagtagta tttactcttt ttatactgct ttcaaaaggc tcatatgttt
    19081 tatacttaat tacttcgtct ttaaaattaa ataaaggtgt atccggctta gcattccata
    19141 aaataatcaa ccacattata gcattataaa gctgctttgc agtttcattc cacttttcag
    19201 gttataaatt tccactccct gtattgtcat attcttgtct attatttaca tgagaatcac
    19261 ctacaagcgg attaaaaaga ggtagccctt tgtgattaat tagttctaaa aaatcccttg
    19321 ccgcacccat gcaacactga ataacttcct tcttgccatc aattttactc tcagcgataa
    19381 atacataata ttcatcttca atagttgctc ctgcatcact atgtttttgt tgatttgcta
    19441 acagcttaat atgtgcttta ggctgaactt caaaatctct aacaattctt tgtcttgttt
    19501 catgtcctct acaattcatt taagttctcc tttacaagtt tagtaactag ccttattata
    19561 ctatataagg tatgaaatgt accataatct tcatcaacta gtttttagaa aatcataaat
    19621 ccatctggag agatgacaag ctgattatcc aattcttggc aattgcttgc tagtgctact
    19681 gcttctttct ctaaaagata atcttctgtt gattggttga atattgcttt gaggatccgt
    19741 ccttcgtatt tccattccag agctactaga tcagagttga tttcttgaag gctatacttg
    19801 ccatgcgaaa tgattactga cgcgtatttc cgaattttaa tcagcctctt cataaagttc
    19861 agcatatcat tgtcacttga tacacgttcc caaggcatac aacgacgaca atctggatct
    19921 ggtcctccag tcaaggctag ctcggttccg taataaatgc acggtgttcc tttttgtaaa
    19981 aagagaaagg ctaaggctga tttaaccagt tgaacatctt cattggccgt ccacaggatt
    20041 cgctctgtat catgtgaatc caagagatta aacatgacct ctgaaatctg ctgcttgtaa
    20101 tacatagact ctccattgat ttcatcgatg aactggtctg tcttcttaat tcctcgtaag
    20161 aaatagtcct tgatactatc agataaagga taattcatga cggcatggaa ctcatctcca
    20221 tttagccaag gctgagatgt atgccagact tctcctagga tataaagatc aggattttta
    20281 gctaaaactg ccttacgaaa atccttccag aactgatggt caatctcatt agccacatcc
    20341 aaacgccaag catcgatatt aaactcttca atccaataag tcgcaacctt taaaagataa
    20401 ttcttgacct ctggattggc tgtatttagc ttaggcatat agtcctcgaa accaaaaaca
    20461 tgatagggta agtctctctt attaactagc ttttcagttg tcactgggaa ttgttgaata
    20521 tggaaccaat ccttataagc agactgttca ccatttttga cgacattttt ccattgaaga
    20581 gattgcgaac caatatgatt aaataccgca tccagcatga ctttcatgcc acgatgatgc
    20641 gcttgatcca ccagttcccg aaaggtctcc ttgtctccaa aatgacggtc aatttcaaag
    20701 taatctgtcg tattgtactt gtgattgctt gcagattcaa agatgggaca aagatatagt
    20761 ccagtaatac ccaagtcttg caagtaattc atatgatcaa taatcccctg taaatcacca
    20821 ccaaagaaat catcgctctt aggtgtgaca gatgaatccc agtctaaagt cccttctggg
    20881 tttaatagag cattgccatt ggcaaatctt tcaggaaata tctgatacca taccgtattt
    20941 gaaacccagt caggaacctt gcaggcatca atctcatgaa gctaaggcaa cttaaatcca
    21001 ttcccaattg catgaagatt ttctagagaa ttttccacac accctttatc gccatacaaa
    21061 atattttgac cttctgtatc tctgagctca aagagatact ggatacgtgc aaagtcaact
    21121 gacacttcaa cctgccaatg gtcaaataag gtaccagaag ttatcttgac catttctttt
    21181 gtatcctgat aaaactcctc cataaagata aaagggtccc catagtgcaa gttgatgctt
    21241 tcaatgtccc ctttcttagt tcgaattcga atatggagtt tcttatcctt ataaagatag
    21301 gcatactccg actcaggcct atggtaaata gcactcaatt ccatcaattt gtctcctaaa
    21361 gtattcattc aaattttacg caaacgtttt caaactcaat gaatccagta tactattttt
    21421 gtaaactatt tgcaaggaat gtccgttgtt aaaggaacta tcttttaaag tatacaaaaa
    21481 gccttaa
//
