LOCUS       NZ_FIXU01000001        13304 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptococcus pneumoniae strain B18210a, whole genome shotgun
            sequence.
ACCESSION   NZ_FIXU01000001
VERSION     NZ_FIXU01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900052895.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 02:58:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,298
            CDSs (total)                      :: 2,246
            Genes (coding)                    :: 2,088
            CDSs (with protein)               :: 2,088
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 62 of 158
            Pseudo Genes (incomplete)         :: 91 of 158
            Pseudo Genes (internal stop)      :: 44 of 158
            Pseudo Genes (multiple problems)  :: 32 of 158
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:33:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2450
            Orig. end                         :: 15754
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FIXU01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13304
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..13304
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13304
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:8304]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8304
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(336..665)
                     /locus_tag="A1M11_RS00025"
                     /old_locus_tag="ERS050419_00005"
     CDS             complement(336..665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /locus_tag="A1M11_RS00025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00005"
                     /product="hypothetical protein"
                     /protein_id="WP_000132575.1"
                     /transl_table=11
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGFL
                     AKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLILNE
                     NQRAN"
     misc_feature    complement(709..727)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.85"
                     /tool="antismash"
     misc_feature    804..817
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.71"
                     /tool="antismash"
     gene            941..1279
                     /locus_tag="A1M11_RS00030"
                     /old_locus_tag="ERS050419_00006"
     CDS             941..1279
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /locus_tag="A1M11_RS00030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00006"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_000682121.1"
                     /transl_table=11
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNML
                     QNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYREIR
                     QKWLKEGE"
     gene            1284..2021
                     /locus_tag="A1M11_RS00035"
                     /old_locus_tag="ERS050419_00007"
     CDS             1284..2021
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /locus_tag="A1M11_RS00035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00007"
                     /product="response regulator transcription factor"
                     /protein_id="WP_050155084.1"
                     /transl_table=11
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKVHHIIPSSFEVFGKPDQLLA
                     EVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQVS
                     ALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYYLET
                     SPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFP
                     NGGSCLIARYKVREVSEAINNLH"
     gene            2035..3375
                     /locus_tag="A1M11_RS00040"
                     /old_locus_tag="ERS050419_00008"
     CDS             2035..3375
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /locus_tag="A1M11_RS00040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00008"
                     /product="sensor histidine kinase"
                     /protein_id="WP_001017622.1"
                     /transl_table=11
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLLG
                     IIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRGVS
                     YFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQKSLT
                     KINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKEKLQE
                     ELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIKEIYDS
                     VLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEIQVEGMS
                     LLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGIDISEIFSF
                     GASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(3417..3572)
                     /gene="blpC"
                     /locus_tag="A1M11_RS00045"
                     /old_locus_tag="ERS050419_00009"
     CDS             complement(3417..3572)
                     /codon_start=1
                     /gene="blpC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /locus_tag="A1M11_RS00045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00009"
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="WP_000358817.1"
                     /sec_met_domain="L_biotic_A (E-value: 3.6e-06, bitscore:
                     20.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKAL
                     ELPIQL"
     gene            complement(3629..4990)
                     /locus_tag="A1M11_RS00050"
                     /old_locus_tag="ERS050419_00010"
     CDS             complement(3629..4990)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /locus_tag="A1M11_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00010"
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="WP_061746974.1"
                     /transl_table=11
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKEI
                     TVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTALAT
                     QLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTNTEV
                     SNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRYLVAS
                     QGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVLRTQFL
                     QTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRIPTGTEI
                     AQIFPIITDTREVLITYYAASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQTIDQTPT
                     RTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILTHSD"
     gene            complement(5001..6677)
                     /locus_tag="A1M11_RS00055"
                     /old_locus_tag="ERS050419_00011"
     CDS             complement(5001..6677)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /locus_tag="A1M11_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00011"
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="WP_306452769.1"
                     /sec_met_domain="TIGR01193 (E-value: 1.4e-265, bitscore:
                     876.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKST
                     LGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTG
                     EIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFII
                     FSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKS
                     FKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMEN
                     IINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDT
                     LTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRR
                     HINYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSD
                     GAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAH
                     RLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            complement(6571..7158)
                     /locus_tag="A1M11_RS13710"
                     /old_locus_tag="ERS050419_00012"
     CDS             complement(6571..7158)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /locus_tag="A1M11_RS13710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00012"
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="WP_000205166.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-42, bitscore:
                     138.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTN
                     KEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQTK
                     KDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDF
                     QTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            7438..7692
                     /gene="blpM"
                     /locus_tag="A1M11_RS00065"
                     /old_locus_tag="ERS050419_00013"
     CDS             7438..7692
                     /codon_start=1
                     /gene="blpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /locus_tag="A1M11_RS00065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00013"
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="WP_001093255.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.6e-19,
                     bitscore: 61.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGLG
                     TAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            7708..7911
                     /gene="blpN"
                     /locus_tag="A1M11_RS00070"
                     /old_locus_tag="ERS050419_00014"
     CDS             7708..7911
                     /codon_start=1
                     /gene="blpN"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /locus_tag="A1M11_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00014"
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="WP_001099490.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.2e-13,
                     bitscore: 44.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGPW
                     GAAIGGIGGAVVCGYLAYTATS"
     misc_feature    complement(8132..8147)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            8155..8304
                     /gene="blpO"
                     /locus_tag="A1M11_RS00075"
     CDS             8155..8304
                     /codon_start=1
                     /gene="blpO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /locus_tag="A1M11_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="WP_001809846.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.2e-11,
                     bitscore: 37.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGC
                     ATTV"
     gene            <8340..8405
                     /locus_tag="A1M11_RS13865"
                     /pseudo=""
     CDS             <8340..8405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863320.1"
                     /locus_tag="A1M11_RS13865"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /pseudo=""
                     /transl_table=11
                     /translation="VTGAAGGAILGGVAYAATCWW"
     gene            8408..8527
                     /locus_tag="A1M11_RS00080"
     CDS             8408..8527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /locus_tag="A1M11_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="WP_001829206.1"
                     /transl_table=11
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSPKKDTDSTP"
     misc_feature    complement(8663..8676)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.08"
                     /tool="antismash"
     gene            8826..8990
                     /locus_tag="A1M11_RS11485"
                     /old_locus_tag="ERS050419_00015"
     CDS             8826..8990
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727116.1"
                     /locus_tag="A1M11_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00015"
                     /product="hypothetical protein"
                     /protein_id="WP_078138045.1"
                     /transl_table=11
                     /translation="MKKKILIIFALYLIMSIFLYPLRESIWYQLFYTIAYVIAVMIYLA
                     LTKKKGAKK"
     gene            9013..9371
                     /locus_tag="A1M11_RS12925"
                     /old_locus_tag="ERS050419_00016"
                     /pseudo=""
     CDS             9013..9371
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /locus_tag="A1M11_RS12925"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00016"
                     /product="immunity protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIFFVRLFLGQLPLLVSTYLFLFRQFSNFF"
     gene            9454..9837
                     /locus_tag="A1M11_RS00090"
                     /old_locus_tag="ERS050419_00017"
     CDS             9454..9837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /locus_tag="A1M11_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00017"
                     /product="hypothetical protein"
                     /protein_id="WP_000877381.1"
                     /transl_table=11
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGVF
                     LLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHIFI
                     VFNALMYLLSSSQVSLKKNKLSS"
     gene            9889..10578
                     /locus_tag="A1M11_RS00095"
                     /old_locus_tag="ERS050419_00018"
     CDS             9889..10578
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /locus_tag="A1M11_RS00095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00018"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_000760532.1"
                     /sec_met_domain="Abi (E-value: 1.7e-13, bitscore: 44.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFVW
                     IQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKHVQ
                     STAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDLLLP
                     SILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLPFLLT
                     FLHRVLG"
     gene            10620..10868
                     /gene="blpZ"
                     /locus_tag="A1M11_RS00100"
                     /old_locus_tag="ERS050419_00019"
     CDS             10620..10868
                     /codon_start=1
                     /gene="blpZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /locus_tag="A1M11_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00019"
                     /product="immunity protein BlpZ"
                     /protein_id="WP_050243733.1"
                     /transl_table=11
                     /translation="MYKHLFFLDSKTLDWLTPYILVLASDTIAFNVFVLTFVSAVIFNF
                     LNPMLSLMAIFLGAGYVVGFWLLKWFVLERLELKDDA"
     gene            10898..11509
                     /locus_tag="A1M11_RS00105"
                     /old_locus_tag="ERS050419_00020"
     CDS             10898..11509
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /locus_tag="A1M11_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00020"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_000394034.1"
                     /sec_met_domain="Abi (E-value: 1.2e-20, bitscore: 67.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSFL
                     VTSLSVAYARKFEMISFGMLSKKELLLFIAIFLLSVLETLVYIHFFAISSGAGVQHLAE
                     VSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSNVPS
                     FIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLTYL"
     gene            11671..12465
                     /gene="ccrZ"
                     /locus_tag="A1M11_RS00110"
                     /old_locus_tag="ERS050419_00021"
     CDS             11671..12465
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /GO_function="GO:0004747 - ribokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /GO_process="GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ccrZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /locus_tag="A1M11_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00021"
                     /product="cell cycle regulator CcrZ"
                     /protein_id="WP_000362996.1"
                     /sec_met_domain="APH (E-value: 2.3e-19, bitscore: 63.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLGDNELTLTPIPGKSGKAYMGRYPDGKRIFVKMNTSPILPGLA
                     REQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQLS
                     RLGYAMETPVDLLQSWQKTAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDVRHS
                     NWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTVLSKL
                     YWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            12462..13097
                     /gene="trmB"
                     /locus_tag="A1M11_RS00115"
                     /old_locus_tag="ERS050419_00022"
     CDS             12462..13097
                     /EC_number="2.1.1.33"
                     /GO_function="GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="trmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /locus_tag="A1M11_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS050419_00022"
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="WP_001266078.1"
                     /transl_table=11
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEV
                     GSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTDYF
                     EDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSL
                     VSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
ORIGIN
        1 ttacaggagg tagttcgagg attgactagt tttgttttac ttgtggaatt agttgttggg
       61 ttgattacct tccaagaaaa actagccctt ctagccttac taggagctgg tttggtttta
      121 ctagtcttgt atttgcctta tcaggtaaaa cgtcagatgc aggactaaca ttgctgatac
      181 gacactaaaa aagaagttga gttcagtttg tctcagcttc ttttttgtta ctacaggata
      241 atggttggtc cgtagagact tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc
      301 cttaccgtac tcaagtacag cttgcggcta gcttcctagt ttgctctttg attctcattg
      361 agtattaact tggtcttgac ttggtcaaag tggaagcggt cataggcccg ccaagcggcg
      421 cgagttggag catctggatc aagagcgctg agtcccatga gaagactgga agtctggtaa
      481 aatttttcta gttcaatcaa gaatcgatta tccactgttt cagtcttggc tagaaaacca
      541 agaatagagt ttaattgctc ctgaaagcgg acgtcgtcag cgcttgcctg tttgcatgct
      601 tggtaggctt tgtttaagtc agtaatcaaa gtatgagctc ttttgatggg gtctgtatct
      661 gtcatgggaa tgcctccttt aatctgggtg ccagtcttac ttctggcaac tgtgttttga
      721 tactgttagt ttatcacttt taattctttt tttttattca aatctttaat tgtcattgaa
      781 atgtcttgaa ttgcgctgag tgaattttat gataaaatag ttgtaagctc atcatgatgt
      841 tgtagaaaat aatcctttta ggagttttca aagactgttt aggattgggt gtgcttgggc
      901 tagacctttt ctgttattct tttcttagga ggagaatcca atgaaacata tgattattca
      961 gacacagaaa acagtctata aagtaaacat cgacgatatc tactatatcc aaacacatcc
     1021 aactaaagcc cataccgtac agattgttac agaaaaagct agttttaata tgcttcaaaa
     1081 tttaagtaat cttgagaacc aatgtgggga aactttgatg agatgtcatc gaaattgttt
     1141 ggttaatctt gataaattaa aatcgattga ttttcaagaa agaatccttt ttctcggaga
     1201 agaaggtcaa tatgctgtca agtatgccag acgtcgctat agagaaatac gtcaaaaatg
     1261 gttgaaagag ggagagtaag aagatgagaa tatttgtttt agaagatgat ttttcccaac
     1321 agactagaat tgaaacgacg attgagaaac ttttgaaagt acatcatatc attcctagct
     1381 cttttgaggt atttggcaag ccggaccaac tgctggcaga ggtgcatgag aagggggccc
     1441 atcagctatt ctttttggat attgagattc gaaatgaaga gatgaaggga ctggaagtgg
     1501 ctagaaagat tcgggaacaa gacccttatg ccctaatcgt ctttgtgacg actcactcgg
     1561 agtttatgcc tctgtccttt cgctaccaag tgtcagcttt ggactacatt gataaggccc
     1621 tttcggcaga ggagtttgaa tctcgtatcg agacagccct cctctatgcc aatagtcaag
     1681 atagtaaaag tctggcggaa gattgctttt actttaaatc aaaatttgcc caattccaat
     1741 atcctttcaa agaggtttac tatctcgaaa catccccaag accccatcgt gttattctct
     1801 ataccaagac agacaggctg gaatttacag cgagtttaga ggaggttttc aagcaggaac
     1861 cccgtctctt gcagtgccat cgctcttttc tcatcaatcc tgcaaatgtg gtgcatttgg
     1921 ataagaaaga aaaactcctt ttctttccca atggtggaag ttgtctgatc gcgcgttata
     1981 aggtcaggga agtgtctgag gctattaata acttacactg agctaggaga gtttatgaac
     2041 attgcttgga tattgttgta tgcacttgtt attaatggac tagaaattgt cattttcttt
     2101 aaagtagatg gaattggtct cactttcgat agaattttta aggcctttct tctgaaattt
     2161 cttctaggga tcatttttac gacttttcaa tttttggctg taagtaaata tttgtcctat
     2221 tttatagaac ctttgttcgg tataggtcta tctttcttat tgttaagagg gcttcctaaa
     2281 aaaatcctta ttttttatgg tctcttccca atgatattag tagagctctt ttacagaggt
     2341 gtttcctatt ttgtgcttcc atttttgggg caaggaattg tagatgggga tggcaatcca
     2401 atctttttat tgattatgat attcgtttgc ttcatagttt tagtcttttt gaaatggtta
     2461 gactatgatt tcactagatt gagaagggag tttctagata caggttttca aaagtctctt
     2521 actaagatta actgggcaat gggggcttat tatctagtga tgcaaagtct atcttacctt
     2581 gaatatgaac aaggtattca atcaacgact gttcgccatc tcatcctagt gttttaccta
     2641 ctctttttta tggggggtat caagaaattg gatacctatt tgaaggaaaa acttcaggag
     2701 gaactgaacc aagagcagac cttgcgctac agagatatgg aacgctatag tcggcatata
     2761 gaggaacttt acaaggaaat tcggagtttt cgccatgact acactaacct cttaaccagc
     2821 ttacgtttgg gcattgaaga ggaggatatg gagcagataa aagagatcta cgactcggtc
     2881 ttaagggatt ccagtcagaa attgcaggac aataaatatg acctgggcag attggtgaat
     2941 attcgtgacc gtgctctcaa gagtctccta gctggaaaat ttataaaagc tagagaaaag
     3001 aacattgtct ttaatgttga agttcctgag gagattcagg ttgaggggat gagcctactt
     3061 gattttctaa ccattgtgtc tatcctttgt gacaatgcta ttgaagctag tgcagaggcc
     3121 agtcaacctc atgtttcaat cgccttttta aaaaatggag cacaggagac ttttatcatt
     3181 gaaaactcca tcaaagaaga gggcatcgat atttctgaaa tcttctcctt tggagcaagt
     3241 tctaaagggg aggagagagg agttggtctc tataccgtta tgaaaattgt ggaaagtcat
     3301 cccaatacca atctaaatac tacctgccaa aatcaagtct ttcgtcaggt acttactgtg
     3361 atacatgcag aatgataaaa aacaagaccg agagttcttg tttctcggtc ttgtttttat
     3421 agctgaatag gtagttcaag tgcttttgtg attttaaatt tacttaaaat tgtttcatgt
     3481 aagagttctt cccaccatcc tccacctgta atttggttga gttcggtagt tgttagttct
     3541 tgaaatgaag ttaggttttg tttcttatcc atgttatgat tctccttttt gataagataa
     3601 taaatagtta tagagtgtta tctgaaaatt aatcagaatg ggttaaaatt ttatctttga
     3661 aataatcaaa atatgttttc tttgcagtta cactagtgac gcgaccttgt aagccatatt
     3721 ggatgagttt actatcctca ttagatagtt ttgcaagagc ggttaattta aagagattgc
     3781 cttgctctgt tctggtagga gtttgatcaa ttgtctgaag ttggccgatg atggtaatgc
     3841 cgtgatttcc aatcttctcc agttttaatc ttacagtttg tcctttatct agtagaggta
     3901 gatagtcaga agctgcgtag taagtgatta gtacttctct tgtatctgtg atgataggga
     3961 atatttgagc aatttctgta ccagttggaa ttctattttt accttcaaat tcgctgttca
     4021 gatgaacgat acctttactt ggagcggtta aggtattgtt ttctaagcgc tgtgtcgctt
     4081 gatctagttg tacttttaat tctgttaatt ggttctccac ggttagttgt tgctgagaag
     4141 ctgtttgtaa aaattgagtg cggagtactt caattttggt tgctaaacta ttatcataag
     4201 ttgctacact tccgatacca gcttgctgaa ttttgaggct tgcgatagat gattcaagac
     4261 ctgcaatact ttgattaatt tgagataaaa atggctcctc tgccgttcct tgtgtttgtc
     4321 cttgtgaggc tacaagataa cgattcaaaa ttgactggtg tggattgcta gttggtaagc
     4381 gtgctctgtt atttatgata gcatctctca gctcttgata ttctccaatt tgttgttgaa
     4441 cttttgtaat ttcttgttca atagctgatg aactgctatt ggcaagatta gcttgatttg
     4501 aaacttcggt gttagtcttt gtgataccca gttcaatatc atgggattgt ttagtaaaat
     4561 tcataaaggt attatggtag ccaaattcat cctcgccaga aaaaagatca gtcgttgttt
     4621 ctaagctttg tttcaaaatt ccaagtcctt ctttttgctt ctcaagtctt tgtaattgag
     4681 ttgctaaggc agttttctga ctttcttcca ttgtttcaga gtatttgatg agtaagtccc
     4741 ctttttcaac tacttgattt gccactaaat gattagctag gataggatta tcactggttg
     4801 actgaatgga ggcaatgaca cttgtagggg cgatttctcc ttgggaagta acagtaattt
     4861 cttttgtggc aacaagggag aaaatcaaga tgaaagtaaa tagtaatgaa agaggtataa
     4921 ttaacactgt cgcatagtta tggtaacgtc tctgataaaa ctcgacgctt ctaaaaagat
     4981 taggattcat gacattctcc ttatttattg aatagatgat ggtagaaacc ttgcgcctgc
     5041 attaactctt ggtgactacc aacttcaatg attttcccct ggtcaagaac aatgacacgg
     5101 ttggttcgtt cggctatact gagacgatgg gctacaaaga gaatggtttt atcagttagg
     5161 gacataagat tatctataac ctttttctca gtcaagacat caagaccgct agtagcttcg
     5221 tctagtatta aaacaggaga tttagttaaa agagcacgag cgagggctat tcgttgcttt
     5281 tgtcctcctg atagaccagc tccatcagag agctgagttt gatagcccat aggcattctt
     5341 tcaatgtctt gacgaatttc agctaattca caagctctta gaatatcttc ttggctaatc
     5401 atatgattac cgcccaaagt taagttttcc aagatagagc cattaaagat ataggcttgt
     5461 tgtggtaggt aattaatatg acggcgcaag acttttttat caatgttttt aatatcctga
     5521 tgattgatgg aaatatgtcc tttgtagggt tcaaagaaat tgacaatcat tttggctaaa
     5581 gttgttttac cagaaccact aactccaact aggctaacct tatctccttg tttaatcgtg
     5641 agattaatat ctgttaaggt atctcgtcca aaaccatact tataagaaag gtcatcaaat
     5701 tcaatatcgc ccatcaaaaa atgtgaatga acagggtttt cttgaacttg aaattcagat
     5761 tcgactagat agacttcgtt caaacggtta ttagcaacct tcgcagattg gagtttggtt
     5821 tggaggttga taatattttc cataggagtt gtaaagtaag aaagaagtgt gttaaaggta
     5881 atcagctgac cgatagaaat tttactcgac atgactaatt gagcgccaaa ccataggata
     5941 aggatattca gaactaattt tgttccctgc tttaaacttg tttgtaaaat agaatattta
     6001 ctgagcttaa aggatttttc caaataatct acaaattcgc tgtctatatt ttgatagcga
     6061 ttttcttcac tcgtgagcga ctttatagtt tcaatcccgt tgatatcttc gataatggca
     6121 gagctaacca tagaattact ttgcatgaca tcatggttca ttttttcgaa aggcttcata
     6181 aaagaaaaga tgatgaacat gtatatagga atagaaataa gagaaagaag gaagagatta
     6241 gggttttgtg ccagtaagac gccccctaca agaatcagaa tagaaacatc caggaaaaga
     6301 gaaagaatgg tagaagccaa ggcatctata atagagttag catctgtgaa ccgtgaaatg
     6361 atttctcctg tacgacgtgt cgcaaagaaa gacatgggaa gttcaaaaat atggcgaata
     6421 taggataaaa tcacatcaat gcttaatctc tggctcagaa cggttaggag ataatctctg
     6481 gagaagctca tgacttgttg gaggatatag gtgataacca gaccaactga gatgattcct
     6541 aaagttgatt tcatctgatt tggaatgtat tcatccaaga ttccttggag atagtaagaa
     6601 ccacctatat tgataatagt gaccaataag cttgagagaa caatgtaagc aatgagagat
     6661 ttttgtttga aaatcagagg aaggaagctt gcttagtaga ccattctttt tatctttatg
     6721 gggttgatag ctgggtttgg tagctagaaa aatagctact ccagtccatt catagaaaaa
     6781 gcgttctttt gacattttag tgatttttac agaagggtca ggatcaccaa taatcagata
     6841 gtctttcttt gtttgataga caacatagta atgttggagt tttccttctt tgttaacgtg
     6901 aacgataaat ggatagggga catcactcat gtcaaagagc gttttatctg cttgaacagg
     6961 tcttgtttca aagcccattt catcagcggc ttttacaatg ccaagagcag tcgtcccttc
     7021 tttattggtc tttgcaagtt ctctcaagtg agctagagaa aaatctgaac catagaattt
     7081 agcaatcgaa gctaaggcag cgacaccaca gtctctcgca tctatttgag gaacaaatgt
     7141 acgtttataa gaagtcattg gcaattcctt tcatatagtg gataggtcta ttatgtcata
     7201 aaactaagtt catattttat gaaatcttga atagtcatta aaacttcctg aatggtaaaa
     7261 aagtgattag aaattatttt tttaaacatt tagaggtggc ttgaaataaa aaagctaatt
     7321 caagacgttt cgatggcaat tcaagatttg gatgaaaaaa attaaaaaat aatgatatac
     7381 taaacttgtc aaagttgcaa caagacaaaa attaaaaata aaaaaggagt atttgttatg
     7441 aatacaaaaa tgatggaaca atttcatgaa atggatatag ctatgttatc tagtattgaa
     7501 ggaggcaaga ataattggca aactaatgtc ttcgaaggtg gtagtgctgc ttttggtggc
     7561 tgggggttag ggacagctat ttgtgctgcg agtggtgtcg gagcgccatt tatgggagca
     7621 tgtggataca taggagctaa atttggtgtg gctctttggg caggagtaac aggggcaacg
     7681 ggtggatttt aacaaaagga gacttgtatg aatacttatt gtaatataaa tgaaacaatg
     7741 ctgagtgagg tttacggagg taattccgga ggagcagctg tagttgctgc tttaggttgt
     7801 gcagcgggtg gagtgaaata tgggaaaatt ctaggaccat ggggcgctgc aataggagga
     7861 attggaggag cagtggtttg tggatattta gcctataccg ctacatcata aaaatgaaag
     7921 ctaaatttta tgaaggctat attctttatt attctcttcg cttttcaaac ctatcttatt
     7981 tatctatcca taagtatctc tgataaaaaa caaaagacta ttgaattaac atcattgaat
     8041 tgttttgtca tattatttct aatctatgat aaattaattt ttctctttat tgcctatgtt
     8101 tttttgataa tttttatatt aaacttgttc cgtaactgaa aagtgacata ctatatgaat
     8161 acaaaaatga tgtcacaatt ttctgttatg gataatgaaa tgcttgcttg cgttgaaggt
     8221 ggagatattg attggggaag aaaaattagt tgtgcagcag gggttgcata tggcgcaatt
     8281 gatgggtgtg caacaacggt ttgacatttc tattgggacc atttgctata ggaataggtg
     8341 taactggtgc tgcaggtgga gctatacttg gaggtgtagc ctatgcagca acatgttggt
     8401 ggtaattatg gattttaaaa gttttattat tggtttagta gttggtatat ttggtcctta
     8461 tatggatgat ttaattagaa aaatattttc aaaatctccc aaaaaggata cagatagtac
     8521 cccctaaaaa ataaatttct cccctgtatt tgctagctta atttacaggg gagtttcttt
     8581 aatattgttt cgcctgtcaa aatgatatgt gatagcagga tgaaaagtct acaaacaagt
     8641 tggtatcaat acaatataaa gaggaaagta tgtttttcat gcttactttt taaatttttt
     8701 aacaattcaa gaggttttga tgaccattta tgatttgagt gatccaaggt caaaataagt
     8761 gctatactag cagtgtaaat gttcttgctc aactaagata aatcgcacat ttaggaggaa
     8821 atcttatgaa gaaaaaaata ctgattattt tcgctctgta tctaatcatg tccatctttc
     8881 tttatccgct tagggaaagt atttggtatc agctatttta taccatagcc tatgtgattg
     8941 cagttatgat ctatcttgct ttaactaaaa agaaaggagc aaagaaatga aagattttct
     9001 tgattaaaaa gaatcatatt ctttgtgaga ttgttcctgg gtcagttgcc tttgcttgtt
     9061 tctacttatc tatttctatt tcgtcagttt tccaatttct tttagtggtt attaacttga
     9121 cttctatttt ggttactgtt tatcttacta gggaaatgag attaagagag tttgaagatg
     9181 atgatttggt tagtcctaga accaatcaac tcatgtttat cggcttgaca ggctttatgt
     9241 ctattatttg tttgtataga gggatcacag caggagaatc ctaccaacaa ataattgcct
     9301 acattggcgc tattctctgc ttgtttatca cgcttctgct catgtggggc ttgaagcatt
     9361 ataaaaagta gctttctatc cttttctgac aggatatttg agtagaaggc tctattaaat
     9421 tgttagtgaa ataaatgaat ggaggtattt aatatgaaat acagattatt ttttgttatt
     9481 ttcttgagta gtgtgttgga tattctttta gggacatttt tacaaatctc tatcgtatct
     9541 attgggtggc ttgttcttta cagtggtttg tttgaagcag gagttttcct tcttgctaat
     9601 aaaggggtgg cggtaaaaat caaggaagta gatattcgaa atcgctttaa atttattttt
     9661 ggaaaaacct tatggtttca aattcttttg ctcatctttt tgataatcaa actttatctt
     9721 ggtttggatg cgaggttgat tttattctat ggacatattt tcattgtctt taatgcctta
     9781 atgtatctat tatctagtag tcaggttagc cttaaaaaga acaaactgtc ttcttaatct
     9841 tacagcagta gagcctgaca aggtgaggtc atagtaggaa gaatttctat gaaaaagtat
     9901 caacttctat tcaaaataag tgcagttttc tcttacttat ttttcgtatt tggtctttct
     9961 cagatgacgc ttattattca aaattattgg caattttctt cccagattgg caatttcgtc
    10021 tggattcaaa atttcttgag tttgctattt agcggagtca tgatttggat tctggttaag
    10081 acaggtcatg gttatctctt tcacattcca agaaaaaaat ggctttggta ttcgattttg
    10141 acagtattag tggtagtgct ccagatctct tttaacgttc agacagctaa acatgttcag
    10201 tcaactgctg aaggttgggc tgtattgatc ggttatagtg ggaccaactt tgctgagcta
    10261 ggtatctata taactttgtt ctttctgact ccacttatgg aagagctaat ctatagagga
    10321 ttactgcaac acgccttttt taagcattcg agatttggcc ttgatttgct tcttccgtcc
    10381 attttatttg ctcttcctca tttttcaagc ctgcctagtt tgttagatat cttcatcttt
    10441 gcaacatctg gcatcatctt tgctagtttg acccgctata ccaagagcat ttatccttcc
    10501 tatgcggtgc atgtgatcaa taatattttc gcaacattac catttttgct gactttttta
    10561 catagggtct tggggtaaaa aaacaaaagg cttgcttttc agccatagag gagattatca
    10621 tgtataaaca cttatttttc ctagattcca aaaccttaga ctggttgacg ccctatattc
    10681 tagtcttggc ttctgacacc attgccttta atgtttttgt gctaaccttt gtgtctgcgg
    10741 tgatctttaa tttcctgaat cccatgctat ctttaatggc tatcttctta ggggctggct
    10801 atgtggttgg attttggtta ctaaaatggt ttgttttgga aaggttagag ctaaaggatg
    10861 acgcgtagga agtctgtttg gtgaggagga tagttttatg gagttttttg ataaatttca
    10921 tgccttatgc tttggatttt tagtactaat aatcgttatt acagttcctt atacgattaa
    10981 ccatggggat ttttttcaaa atgaatctgc attgattatt gtaagttttc ttgtaacctc
    11041 gctgagtgtt gcttatgcta gaaaatttga aatgatttct tttgggatgt taagcaagaa
    11101 agagcttttg cttttcattg caatctttct tctaagtgtg cttgagacgc tggtttatat
    11161 tcatttcttc gctatttctt ctggcgcagg agttcaacac ttggcggaag tcagcagagg
    11221 aatttctctg tctttgattt tgactacctc agtttttggc cccatccagg aggaactcat
    11281 tttcagagga cttcttcaag gtgcggtttt tgacaactct tggttagggc ttgtgctaac
    11341 ttcctctctc ttttctttca tgcatggacc ttctaatgta ccttcgttta ttttttatct
    11401 acttgggggc ttgttactgg gctttgctta taaaaagagc caaaatttgt gggtttctac
    11461 tctagtccac atgttttaca acagttggcc actcttaact tatttataaa aatcatgaaa
    11521 aggtaagtag gagattgtgc ttaccttttt ctttctataa tgatactcaa gccaatccag
    11581 aggcttttat ttgagaatcg ggtgtggagc ggttgacgaa taggccaaaa actagtagaa
    11641 tagtaaggaa actttatacg gaggaaagaa atggatttgg gtgataatga gctaacactg
    11701 actcccatac ctgggaaaag tggcaaggct tatatgggta gatatcctga tgggaagcgt
    11761 atctttgtaa aaatgaacac ctctccaatc ctacctggtc tagctagaga acaaattgct
    11821 ccacaattat tatggagtcg tcgtttggca gatgggcgtg atatgtgtgc tcaagaatgg
    11881 ttgacaggaa agatattgac cccctatgat atgaatcgta agcaaatcgt caatatttta
    11941 acccgtcttc atcgctcacg tccgttgatg acacaattga gtcgtttggg ctatgccatg
    12001 gaaacacctg tagatttact acagtcttgg caaaaaacgg ctccagatgc tttgcgtaaa
    12061 aatcatttta tcagtgaagt gatggctgat ttacgtcaga ctattccagg atttagagag
    12121 gaccatgcga ccattgtcca tggagatgta cgacatagta attggattga gacagatagt
    12181 ggcttgattt atttagtaga ttgggattcg gttcgcttga ccgatcgcat gtttgatgtg
    12241 gcccatatgc tctgccatta tatttcagaa catcagtgga aggaatggtt gacctactac
    12301 ggttacaagt acaatcaaac ggtattaagt aaattgtatt ggtatggtca attgtcttat
    12361 ttgagtcaga tttccaagta ttatatgaac caagatttag aaaatgtcaa tcgggagatt
    12421 catggtttgc gtcatttccg agacaagtat ggaaagagaa gatgagagtt agaaatcgta
    12481 aaggggcaac agaattacta gaggcaaatc cccagtatgt ggtcctcaat cccttggaag
    12541 ccaaggcaaa atggcgggac ttgtttggca atgataatcc cattcatgtg gaagttggaa
    12601 gtggaaaggg tgcctttgtt tcaggtatgg ccaagcaaaa ccctgacatc aactatatcg
    12661 ggattgatat tcaaaagtct gttttgagct acgctttgga caaggtgctt gaagctggag
    12721 tgtctaacat caagctcttg tgggtagatg gttctgactt gactgactat tttgaagacg
    12781 gtgagattga tcgcttgtat ctgaactttt cagatccatg gccgaaaaaa cgccatgaaa
    12841 agcgtcgttt gacctacaag acctttttgg ataccttcaa acgtatcttg cctgaaaatg
    12901 gagaaattca tttcaagacg gataaccgtg gcttgtttga gtacagttta gtgagctttt
    12961 ctcaatatgg catgaaactc aatggtgtct ggctagattt gcatgccagt gattttgaag
    13021 gcaatgtcat gacagaatac gagcaaaaat tctcaaacaa ggggcaagtt atctaccgag
    13081 ttgaggcaga attttaagag atagcctaaa attaggctgt acaagtgctt ttgctttaca
    13141 taagttggca aacgtgctat actgatagta agaatatgaa aagtgaggcg gggaaatatc
    13201 ttcgcctctt gcttatgagg aggtggacgc aatcgcaaca atcgtagaat tagtcagaga
    13261 agttgtagaa cctgtcatag aagctccttt tgaactcgtg gata
//
