LOCUS       NZ_FEEQ01000007        18024 bp    DNA     linear   CON 04-JAN-2025
DEFINITION  Streptococcus pneumoniae strain 2842STDY5644069, whole genome
            shotgun sequence.
ACCESSION   NZ_FEEQ01000007
VERSION     NZ_FEEQ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900047005.1-RS_2025_01_04
            Annotation Date                   :: 01/04/2025 01:43:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,253
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 86 of 184
            Pseudo Genes (incomplete)         :: 88 of 184
            Pseudo Genes (internal stop)      :: 60 of 184
            Pseudo Genes (multiple problems)  :: 40 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:55:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18024
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FEEQ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18024
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..18024
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18024
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[7148:8024](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(7149..8024)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(<1..374)
                     /locus_tag="A1T31_RS05565"
                     /old_locus_tag="ERS367508_01079"
                     /pseudo=""
     CDS             complement(<1..374)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="A1T31_RS05565"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01079"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNYEASKQLTDARFKCLVGVQRTTFKEMLAVLKTAYQLKHTKGGR
                     KPKLSLEDLLMATLQYVREYRTYEEIAADFGIHGFWYPRKKLTPSEPMG"
     gene            complement(382..684)
                     /locus_tag="A1T31_RS05570"
                     /old_locus_tag="ERS367508_01080"
     CDS             complement(382..684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /locus_tag="A1T31_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01080"
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="WP_000590556.1"
                     /transl_table=11
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVNE
                     DLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIILPAKQNMV"
     gene            complement(722..1198)
                     /locus_tag="A1T31_RS05575"
                     /old_locus_tag="ERS367508_01081"
     CDS             complement(722..1198)
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /locus_tag="A1T31_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01081"
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="WP_044814279.1"
                     /transl_table=11
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREAL
                     ITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIASDKEV
                     EVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            1378..1530
                     /locus_tag="A1T31_RS13320"
     CDS             1378..1530
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1T31_RS13320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_001809697.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDETDEVSNHTYSKATLTWFEEIF
                     EEYKN"
     gene            complement(1611..3434)
                     /gene="lepA"
                     /locus_tag="A1T31_RS05585"
                     /old_locus_tag="ERS367508_01082"
     CDS             complement(1611..3434)
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="A1T31_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01082"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047212.1"
                     /transl_table=11
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(3513..4241)
                     /locus_tag="A1T31_RS05590"
                     /old_locus_tag="ERS367508_01083"
     CDS             complement(3513..4241)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="A1T31_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01083"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_000133329.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQAQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            complement(4243..5910)
                     /gene="recN"
                     /locus_tag="A1T31_RS05595"
                     /old_locus_tag="ERS367508_01084"
     CDS             complement(4243..5910)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="A1T31_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01084"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923608.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(5917..6348)
                     /locus_tag="A1T31_RS05600"
                     /old_locus_tag="ERS367508_01085"
     CDS             complement(5917..6348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="A1T31_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01085"
                     /product="arginine repressor"
                     /protein_id="WP_001034415.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(6341..7156)
                     /locus_tag="A1T31_RS05605"
                     /old_locus_tag="ERS367508_01086"
     CDS             complement(6341..7156)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="A1T31_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01086"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041080.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEAGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(7149..8024)
                     /locus_tag="A1T31_RS05610"
                     /old_locus_tag="ERS367508_01087"
     CDS             complement(7149..8024)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="A1T31_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01087"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_000743808.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-57, bitscore:
                     186.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFETESIV
                     SVVESLRING"
     gene            complement(8021..8233)
                     /locus_tag="A1T31_RS05615"
                     /old_locus_tag="ERS367508_01088"
     CDS             complement(8021..8233)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="A1T31_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01088"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(8211..9551)
                     /gene="xseA"
                     /locus_tag="A1T31_RS05620"
                     /old_locus_tag="ERS367508_01089"
     CDS             complement(8211..9551)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="A1T31_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01089"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_044792714.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYELSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMATA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(9679..10317)
                     /gene="udk"
                     /locus_tag="A1T31_RS05625"
                     /old_locus_tag="ERS367508_01090"
     CDS             complement(9679..10317)
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="A1T31_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01090"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     misc_feature    10357..10371
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(10425..10727)
                     /locus_tag="A1T31_RS05630"
                     /old_locus_tag="ERS367508_01091"
     CDS             complement(10425..10727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="A1T31_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01091"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985093.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQTV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(10968..11846)
                     /gene="truB"
                     /locus_tag="A1T31_RS05635"
                     /old_locus_tag="ERS367508_01093"
     CDS             complement(10968..11846)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="A1T31_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01093"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013250.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLYEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     gene            complement(11856..13130)
                     /locus_tag="A1T31_RS05640"
                     /old_locus_tag="ERS367508_01094"
     CDS             complement(11856..13130)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="A1T31_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01094"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_001002635.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEVQA
                     LENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            complement(13226..14485)
                     /locus_tag="A1T31_RS05645"
                     /old_locus_tag="ERS367508_01095"
                     /pseudo=""
     CDS             complement(13226..14485)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="A1T31_RS05645"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01095"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            complement(14633..15430)
                     /locus_tag="A1T31_RS05650"
                     /old_locus_tag="ERS367508_01097"
     CDS             complement(14633..15430)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="A1T31_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01097"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000625730.1"
                     /transl_table=11
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLEAIL
                     ANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     misc_feature    complement(15583..15597)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.52"
                     /tool="antismash"
     gene            complement(15674..16417)
                     /gene="srtA"
                     /locus_tag="A1T31_RS05655"
                     /old_locus_tag="ERS367508_01098"
     CDS             complement(15674..16417)
                     /codon_start=1
                     /gene="srtA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /locus_tag="A1T31_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_01098"
                     /product="sortase SrtA"
                     /protein_id="WP_000078846.1"
                     /transl_table=11
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWN
                     TNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELE
                     MNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNG
                     MKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDL
                     KETKDYSQTSDEILTAFNQPYKQFY"
ORIGIN
        1 tttttacttc cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa
       61 tcgtaaaacc actttgaaca agagttactt caacccattg gctccgacgg agtaagtttc
      121 tttcgtggat accaaaatcc gtggatacca aaatcagccg caatttcttc ataagtgcgg
      181 tattctcgca catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt
      241 cgtccccctt ttgtgtgttt aagttgataa gcagttttta atacagctaa catctcttta
      301 aaagtggtgc gctgaacacc aacaagacat ttaaatcgtg catcagttag ttgtttactt
      361 gcttcataat tcatggaact actataccat attttgtttc gcaggaagta taatattgtc
      421 aaatactgga acgctcattg ctgggataca gaataagatt gggccagctt cgataactgg
      481 gatacctggt tcaaaaccaa ggtctgttgc agcgattggt gtaaagatat cgtaaccttt
      541 cataaggtct tcgtttacat ctttcaccat aactgcatca cagtgaacat cgtaaccacg
      601 gtttgaaagt tcttcttcta gagcactttt aatttggtga cttgagttaa cacctgcacc
      661 gcaggcagca agaattttaa tcatttggat ttcctccgat tttatttttt aatagacaag
      721 attaagcggt tgcttcagca atgtaagcat aaagtttttc tggttcggaa atttttgata
      781 ggtcttcaag atgtccattt cctgtgaaaa agtccatcaa ctgagccaga atatttgttt
      841 gacttgaact tgaattgtta atgataaaga agagtaggga tacttctact tccttatcag
      901 aagctatcat attgtgaaaa gttactggtt tttctaatcg aacaaccacc actttctcag
      961 ctagattatg aacaatatct gtatgaggaa tcgctacatt tggcaagtcc tttcctagaa
     1021 attccatatc taaaccagtt ggaaatgact tttcacgcgt gatcaaggct tcacgataag
     1081 ttggagtgac aatttctcgt tcttccaaca agcttgctac ctgatcaaag agttgttctt
     1141 gattatccgc ttctaagcaa aacacaaggt ttttgtcaaa gaaataatct aataccataa
     1201 ggttttccct tctttccatt aactttatgc tataagtata acactatatg aaatcgttgt
     1261 taattacttt ctattctttt ttgtctcttt ttttatattt ttgttttgtt tatagtttgt
     1321 tatataaaaa taaacacaca aacaaatact ccaagcattt ttctgttcta atactcaatg
     1381 aaaatcaaag agcaaactag gaagctagcc gcaggttact caaaacacag ttttgaggtt
     1441 gtagatgaaa ctgacgaagt cagtaaccat acatacagta aggcgacgct gacgtggttt
     1501 gaagagattt tcgaagagta taaaaactaa aaaagcagac catctaagcc tgctttacta
     1561 ttgattctta tataaatttc ctgtgaacaa ggaaaggcat ttctgataac ttattcttca
     1621 tccatactca agacgctgag gaaggcttct tgcggaactt caactgatcc gatggatttc
     1681 atgcgtttct taccagcttt ttgtttttca aggagtttac gcttacgaga aacgtcacca
     1741 ccataacatt tagcaagtac gttcttacga agggccttga tatcagtacg agcgacaatc
     1801 ttgtgtccaa tagccgcttg gattggaact tcaaattgtt ggcgagggat gattttcttg
     1861 agtttatcaa cgatgagttt cccacgttcg taggcaaagt ccttgtgaac gataaagctg
     1921 agggcatcca ccttatctcc attgagaaga atatccattt tcaccagctt agatgggcga
     1981 tattctgaca attcgtagtc aaagcttgca taaccacgtg tcgaagactt aagtttatca
     2041 aagaagtcaa agacaatttc agcaagagga atttgataga taacattgac acggttatca
     2101 tcaatatagt ccatagtcac aaagtcccca cgcttacgct gagctagctc cattactgct
     2161 ccgacgaact cctgtggtac catgatttgc gccttgacat aaggctcttc aatggtcgca
     2221 atcttagttg ggtctggaaa ctcagatggg ttagacacat ccatagactc accgtcggtc
     2281 aaattaactt tgtaaataac agacggagct gtcatgatga ggtcaatatt gaactcacgc
     2341 tctaaacgtt cctggataac atccatatgg agaagtccaa gaaatccaca acggaaacca
     2401 aatccaagtg cctgagatgt ttctggttca aactgaagac tagcatcatt cagttgcaat
     2461 ttttcaagcg cttcacgcag gtcattgtat ttgtttgatt cgattgggta gagacccgca
     2521 aagaccatag gattcatctg cttataacca tgtaatggtt ctgccgcagg attggttgcc
     2581 aaggtaacgg tatcacccac acgagtatcc tgaaccgtct tgatagacgc cgcaatgtaa
     2641 ccaacatcac cagtcgcaag gaaatcacga ccaaccgctt ttggtgtaaa aataccgact
     2701 tcggccacat caaaggtctt actattgctc atgagctgaa tcttatcacc aggtttgacc
     2761 actccgtcca tgacacgcac ttggaggata accccacggt aagcatcgta aacagagtcg
     2821 aaaatcaagg ccttaagtgg cgccgtcaca tcacccgttg gtgctggtac tttttctaca
     2881 atttgctcga ggatttcttc aatcccaata ccagccttgg cagaagccaa aactgcttca
     2941 ctggcatcca aaccaatcac atcttcaatc tctgtacgca cgcgctccgg atctgcagcc
     3001 ggcaggtcaa ttttattaat gataggcatg atttccaaat cattatccaa agccagataa
     3061 acgttggcaa gagtttgagc ctcaattcct tgagccgcat cgaccaccaa aatagcaccc
     3121 tcacaggcag ctagcgaacg tgaaacttca taggtaaagt caacgtgccc tggtgtgtca
     3181 atcaaatgga aaatataagt ttccccatct tttgcagtgt aattcaactc gatggcattc
     3241 aacttaatag taattccacg ttcccgctct agctccatgc tatccaaaag ctgggcctgc
     3301 atttcacgac ttgaaaccgt ctctgttttt tccaaaatgc ggtctgctag agttgatttt
     3361 ccatggtcaa tatgggcgat aatagagaag ttacggatct tctcctgtcg ttttttcaat
     3421 tcttctaagt tcatgattct cttcctttca gggtatctat ttattataaa ttgtttttga
     3481 tattttgaca agaccatacc ctgctaggag tactaatctt cagcgacaaa gccgtcattt
     3541 tcgataaagt ggtgttctgt cattccttgg tctgtaaaga caatcccgtg aaggacacca
     3601 ccataaacag ctcctccatc cattccaatc ttgccatctt ctgtagtcca aagctcagat
     3661 gtaccgcgtt cttgctgtaa caaaccatag accggtgtat gaccgaagac aatggttttt
     3721 ccagtatgat tttcagctcc gtggaatggt tttctgagcc agactttttt ataatctgtt
     3781 gtttcatgcc agtcatccaa ggtcaaatca atacctgcgt gaacaaagat atacttgtct
     3841 gtctctacta caaatggcat ttgacgaatg aactcgacca agtctgccgc ttcagcggca
     3901 acccgcttgg catcttctac tccatcaact ggtgcatcca agggacgacc taggatagag
     3961 ttaatggttg tatctccacc attgcgacga taatggtcat aactttcttc tgggtcatct
     4021 agccaagtca aaaacatata ctcgtggttt ccggacaaac agatagcccc ttgattgtcc
     4081 accaagtcct tgaccatttc aagaacacgg tgactatcct cacctctgtc aatcaaatca
     4141 cctagaaaga gcaactgggc ctgaccatcc caggttttga gaaggtcttc cagcatccca
     4201 gcttttccgt gaacatctcc aattacataa tagtctgtca tcttatttct ccctgtttct
     4261 caacaattct ctggcttgcg tcagggctgc ttctgtcaca tcatcacctg ccaacatctt
     4321 ggcaacttcc tccactcgct cttcgaccgt caaaagacga acagtcgaaa ccgttgaatg
     4381 gtcattacta atcttctcaa taaagaattg ataatctgca atcgcaatta cttgtggcaa
     4441 atgggagata gccaaaacct gaccatgctg accaatttta tgaattttct gagcaatagc
     4501 ttgagcaaca cgacctgaaa ctcccgtatc cacctcatca aagacaatgc tagtcttgcc
     4561 ttctttacgt gaaaaggcag acttaatggc taacatgaga cgagataatt cccctccaga
     4621 agcaacctta accaagggtt taaagtcttc tccagggttg gttgaaatat aaaactcaac
     4681 catttcattt ccctcacgac tgaattttcc cttactaaaa cgaacctgaa actgggcttt
     4741 ttccatataa agatcttgca gttcttgttt aatctcagct tcgagttgct gagccaaatt
     4801 atgacgggca gaagcaagtt gacctgccaa attgacaaga ttgacttcca acttcttaag
     4861 ctctgcttcc atgtcctcag acgaaagatt attgcctgtc aagagattgt attcttccgt
     4921 aatcttagca aaataaagca aaacatcatc aacagtccca ccatacttac gagtaatagt
     4981 atgaaggagg tgcaaacgat tctcaacctg catgaggcga ttgccatcaa aatcaaggtc
     5041 ctcaatgata gcttccaaac gtttgctaat gtcttctaaa acatagtagg tctcagacag
     5101 agagcttgaa atttcacggt attcagggtc atactcttcg acactttcca tgtcattcat
     5161 ggctgaacga acattggcca gacttgaaaa atcttcattg tccaacatac tgtaggcatt
     5221 ggtcagtgta tccgcaatat ttttgtggtt gaggagttta tctcgctctt gattgagagc
     5281 caagtcttct ccagcctgca agtttgctgc ctcaatctct gccatttgaa attccaacat
     5341 ttcgatacgt gccttgtgtt cctgttggtt tttcttgact tccagaacct gcttgcgcat
     5401 tttccgatag gcatcaaaac tcgtttgata ggtttctttc aagtcccaaa aagcggcatc
     5461 accaaattca tccaacatct ggatatgcag ttggggacgc attaactcct catggtcatg
     5521 ctgaccatga atatctacaa gatgttgccc aatagctcgc aaaacagaca gattaaccat
     5581 ctgaccattt acacggctga tactacgacc attttgcaag atttcccgac ggatgataat
     5641 ttcatcacct aattctaaac cttgctcatc aaaaatttcc tgtaaaagac gactattctc
     5701 aactgagaaa agcccctcaa tctctgcctt tggtacacca tgacgaataa catctgtcgt
     5761 cgcacgagct cccaacatca tattcatggc atcaatgata atcgacttcc ctgcacccgt
     5821 ttcaccagtc aggacagtca tccccttttc aaaattgagg gaaatagcct caataatggc
     5881 aaagtttttt atcgaaattt caagtaacat atagacctac caatttttta cttgttcaaa
     5941 gatttcctct gctagacttc cacttctggc aatgactaaa atcgagctat catcagtcaa
     6001 acagctaaaa atcttgtctg caaaagtctc gattaactga gcttttacaa aagccgtatt
     6061 tcctggaata acttggagat tgatcatctt atccatcaat tcagccgatt cgatattgtc
     6121 ttcagccagt tgcagacttt ttacgattga ttttggtaat tcgtagacat aggtgttgtc
     6181 tctcaaagga attttgacaa tacctaactc tttgatatct cgggataccg tcgcctgagt
     6241 ggcagtgata cctgcttctt tcaaatgttc tacaatttct tcttgcgtgc cgatttgata
     6301 atctgtcacc aatcttctaa ttttttcaag tctttctttt ttattcattt ttaaattgac
     6361 tatgcgccct ctctactgct tctttaatct cagcaagaat ctgattgctt gctgactttt
     6421 cttttttcaa atacgctaaa aattcaatat ttccatgtcc accttggatg ggagaaaagt
     6481 ccaagccaag gactgaaaaa cctgcctcta ctgccatagc tgttacagat tcaaggacat
     6541 tctgatgaat cttaacatct cgaataattc catttttccc aatctgctca cgtcctgcct
     6601 caaactgagg tttgacaagt gctaccacct gaccttgatc agccaagaca cggtgcaagg
     6661 ctggcaaaat cagactaagg gaaatgaaac tcacatcaat actggcaaag ctcggctcct
     6721 gctcgaaatc agtcttttca gcatagcgga aattgaactg ctccatgctg acaactcgtg
     6781 ggtcttggcg taatttccaa gccaactgat tggtcccaac atcgactgca aagaccaact
     6841 tggcactatt ctgtagcatg acatcggtaa aacctccagt agaggccccg atatcaatcg
     6901 tagtcgcgcc atccaccgac aaatcaaaga cctgcaaggc cttttccagt ttcaaaccac
     6961 cacggctgac atacttgagt ttctccccct tgagttttaa ttcggtgtca tctggaattt
     7021 tctctcctgg cttgtcaaac cgttctccat taaggactgc tacgactagg ccagccatca
     7081 cacctcgctt ggcctgctct ctcgtttcaa acaacccctg tttataagct agtacatcca
     7141 ctctttcctt agccattgat tctcaaactt tctactacac ttacaatcga ttctgtttca
     7201 aagggaagct gctgggcaat ttcttctaat ttttcattag cttgatccag ggtttggtta
     7261 caaaaggcaa tggactcttc caagcccaac aaggcaggat aggttgattt ttctgcctgc
     7321 agatcctttt gaggtgtctt gccgatttcc tcaaaactag ctgtcacatc cagtacatca
     7381 tctctgactt gaaaagcaag tccaatcaat tcacccacag ttttcagctt cacctgcatt
     7441 tcaggtgaca attcagctat aatagctgcc gcttggaagg gataggctag taacttccca
     7501 gtcttattgg catgaatagt ctgaagttct tccagagaca agtgctggtg ttcgccctcc
     7561 atatccaaaa cttgccctgc caccataccc agactacctg aagcaaggga taagttggca
     7621 atcaagtcca ccttgatctg acttggcaaa tctgcctgcg caatcaaggc atatgggtct
     7681 aagaataaag catctccagc caaaatggcc atagcttcac cgaatttctt gtgattggtt
     7741 aaccgccctc ttcgataatc gtcatcatcc atagcaggaa ggtcatcgtg aatcaagctc
     7801 cctgtatgaa tcatctccaa ggcagtagct acctgcgcgt gagcaggttt gatggcaacc
     7861 tgcaaagctt ctagaacttc taacaagaga aaaggccgaa tacgcttgcc accagcatga
     7921 atagaataga gaacagactc ccgtaaacta gaggcaaact gctggtctcc ataaaaatct
     7981 tccaaagccg actcgacaag agctaatttt tcttgctttt tcattcaaaa tcactttctg
     8041 ttccgtcttc ttgcatgacc tttaccaagg tcttttcagc cttgtccagc gtagcttgga
     8101 gctcttttga caagaccatg cccttttgaa aggcagtaat cgcatcttcc agagcaattt
     8161 caccattttc caaactttgg acaatggttt ccagttctgc tagattttcc tcaaatttct
     8221 tttgttttga catctttaac ctctaattct acttgaccat ctcgcatcaa aagcgttact
     8281 tggtcttttt tcttcaaact ctcaaccgaa tctacaatgg actcttcttt tttgacaata
     8341 gcataaccac gcgccacgat tcggctagta tccaacatga gcaaagcttc cgaaagtcgc
     8401 ttggcctcag caaccttggc gtcataaact aacgccattt ggctacctaa gagcttgtcc
     8461 aactgtccta aacggtcttg atagcgttgg attttggtaa caggtgataa ttgtactaat
     8521 tgatgagttc ttgcttgaac taattgtttg ttatcagaaa tccgagttcg caaactttgt
     8581 ttcaaacgca gttgtagttg gtccaagcgt tgcaaataac cgtcatacaa gcgctcaggt
     8641 tgtctaaaga taacagactg actgcatttt ttcaaagcct cttgtttctt agatagaaca
     8701 tttcggactg ccgttgccat ccgtttttcc tgattttgca aatgagctaa tacatccaac
     8761 ttggtcacag gtgttgccag ttcagccgcc gctgttggcg ttgcagcgcg tcgatctgcc
     8821 acaaaatctg ccaaggtcac atccgtctca tgccccacac tagagataac tggcaaacga
     8881 gattcaaaaa tagctcgtac cacaatttct tcgttaaagg cccagagatc ctcaatagaa
     8941 ccacctccac gaccaataat gagcaaatcc aaatcgtccc gttgattagc acgcgcaata
     9001 tttctagcaa tttcctccgc agccccttca ccttgaacct tggtcggata aagaaggatg
     9061 tcaacacctg ggaatcgcct gctgacggtc gtgataatat ctcgaataac ggctccacta
     9121 cggctggtta ctacaccaat tctcttagaa aattggggca gagcttgctt gaagcgttct
     9181 tgaaacaggc cttcttctgt caattttttc ttaagttgtt caaactgaat cgcaagcgcc
     9241 ccaaccccat caggctcagc tttttcaatg atgatggagt agctaccact tagttcatag
     9301 acctgtacac gcccaatcac attgatcttc attccttctt ccaggtcaaa ccctaatttc
     9361 tgataaatcc cagaccagat ggtcgcttga ataactgcat ggtcatcctt tagggagaaa
     9421 tattggtgag taggtcgttt acgaaagttg gaaacttgac cagttaaata gacccgttcc
     9481 aagtatgggt ctttatcgaa tttcattttc agatacttgg tcaaagttgt taccgataaa
     9541 tacttttcca tctccaccta ctattcattt acttgctctt tcatgggtat tattatacca
     9601 aaaatatgcc taaaaatctc catttatgta ccattatgag ggaaaaatag aaaaaggagg
     9661 caaggcctcc acatgtgatt atttgctgtt tcgagcttct tccaaaatct ttgcaatctt
     9721 ggtcgtcaac aggtcgatag ccacggtatt gctaacccct tcaggaatga cgatatcagc
     9781 ataacgctta gttgactcga taaactggtg gtacattggt ttgaccacac ctaagtactg
     9841 gttaataacg ctatcaaggc tacggccacg ctcctccata tcacgcttga tacgacgaat
     9901 aatgcgcaca tcgtcatccg tatccacaaa aatcttgata tccatcaaat cgcgcagacg
     9961 cttgtcctcc aagaccaaaa tgccctcaac gataaagaca tcttgaggct cctgacgata
    10021 ggtcttgcta ctccgtgtat gctctgtata gtcgtaggtc gggatgtcca ccggacgccc
    10081 tgccaacaat tccttaatct gctcgatcat caagtctgta tcaaaggcaa aaggatggtc
    10141 atagttggtt ttgacacgct cttcaaaggt caaatgagac tgatccttgt agtatgaatc
    10201 atgctcaatc atggaaatct tttcatcagg aaaatgcgat aaaatggctc ttgaaacact
    10261 ggttttacca ccaccagaac cacctgtcac tccaataatg attggtctat tttgcatgct
    10321 atcctccgtt attttatccg tcgtctattc tatcacattt tttacaaaat ttatagtctc
    10381 atcagcaaaa aacaccagag tcttccctct gatgttcgac agttttaacg aaagccctgt
    10441 agggtttgag caagcatctg caagaaagcc agtctccctc tttcctggct aggagctttg
    10501 gcaatccata aaccaaaatc aatgacagac ttaggtgcct ggtaatgatg cgtcatgagg
    10561 taaagtgaca acccttgact caaattggcc atgaccgttt ggtatttttc atttctgtct
    10621 aaattttgta tagcaagacg aaacaggtga ctcaactcac tattttcatt tatttctttt
    10681 tgttgaagaa gttgctccac cctttctcga aactcatttc gcatcatgga attatcacac
    10741 caaatcctgg gcctaagttc ccaccagaac ctgtaatgga ctctaaatat ttatctgaaa
    10801 gaattttaaa ttgcttcatt tcacacctct aaatttctat atagattatt tgagtaccta
    10861 caactcgcaa caattggaat attataattc ccaaaaccat tctactatta gtatggggtt
    10921 ttatcaagca attgttatct atcacccgat ttttattcct aaacgatcta gctaaaaacc
    10981 ttccttggct tatagagatt gccccgtttt tctagaatgg ctaacaattt atcatcttca
    11041 aaggcagcca gttctttgtc cgtttggtct agctcaataa aacgaccaaa gcgaacttct
    11101 gtagcctctt ctggagttag gaaaactttg acaaggtcac ctgtcccaat ctctaaagga
    11161 tggagaaaat ctaattgccc agcctctact ttttcagcaa tttcctccaa ggaaagagcg
    11221 tcttctaatt gtaagccagc agcactagta cgagtcaaat gggacatatg agccgcataa
    11281 ccaagctttt cacccaaatc aactgacaaa gtacggatgt aagtcccttt actgcatttt
    11341 acacgaaaag tgaatcgggc aagttggcca tcataagaaa tcggacttgt tcgctcaaat
    11401 tgataaatga tcacctgacg ttctggacgc tccacttcct gaccagcacg cgcatactca
    11461 tagagcttgc gaccattaac cttaactgcc gaatacatag ggggaatctg ggtaataggc
    11521 ccagtcaagc tagcaatcgc ttcatcaaca agcttttcat acaagggaga caaaacaggg
    11581 gtttctgcga tcacttcccc actagcatcc tcagtcgtcg tggaataacc cagagtaatt
    11641 tccccctcat agatcttacc ctcgtcctgc ataaactcga ccatgcgtgt cgccttgcca
    11701 accgcaatcg gcaaaacacc caccacatcc ggatccaagg ttccaccatg accaattttc
    11761 ttggttccca aaatcttacg cagtttaaaa accgcatcat gcgaggtcat tcctgcttct
    11821 ttttttaagt tgataatacc gttcattttt gctttctact cccccttcag tgcttcgaac
    11881 ttcgctttca ttgttggatt tttccgggtc aattttttaa cagagacatc ttccaatttg
    11941 ttgttagcta gacggagttg gttttcagat gtagtcagga atttcttaac ctcttccatg
    12001 cgtttgatgg ccttgtcgat ttcatcaata gcttttccaa agttagtcga agctgaatta
    12061 tagttcttag caaaagctag cttaaaggca tccaaatctt cctcaaaatg cgtaatgtca
    12121 atattttgct cgcgaaccaa ggccaactcc tgcttgtatt ttagggaatt tagcgccgca
    12181 ttacgtaaga gaccaatcaa ttggataaag aattgaggac gaacaacata cattttttca
    12241 tactcgtgac tgacgtcaac aatccctgtg ttaaagtagt cattatcagc ctcaagcatg
    12301 gtcaccaaaa cggcatactc acagttcttc tcccgacggt ccttgtccaa ttccttgtaa
    12361 aaatctgcat tcttgtgctt cttctctgtt ccgtccgctt cgtttttcat ctcaaacatg
    12421 atagaaatga tttcaactcc attttcatca cactcacgga agataaagtc ccctttagac
    12481 ccacgcgaag agaccttgtt atccttctca aagtaagcat ttggaaaggc gaaactacga
    12541 accttgttaa actcactctc tgcatactgt tctaggcttt ccccaatcgc ttttgtagat
    12601 tgttgagcct taaaattctt ataaaactcg acttgttcac tggctgcttt gagctgggct
    12661 tcgtagtttt gcttaacaga agccaaagac aactcatttt ccttttcttg cagtaggagc
    12721 tgatttttga cctgattgcg ttctttttct aggtcagaaa gggtcttttg caattgattt
    12781 tcatgctcca aacgcaaggt cgccaactgg ttttccaagg cctgtacttc cttgtcctta
    12841 gccaataagg cctgatggct tgtctgttca acttctttct tggccaattc tttttctgta
    12901 tcaaagtttt ggatttgact ctgcaattgc gcaatttctt gatccttctg agccagttta
    12961 gtctgttgct cattcatagc cttttgctca gccaaggcca gttcctgcct catcctatcg
    13021 tgtagttcct tatcaaactc tgccgttctc acttgggaca aaagttcagc atactggctt
    13081 tcatttactg taaagacttc cccacagttg ggacatttga tttcgttcat tacattcctc
    13141 tttctagact tctgtaacca ttatatcatg cctgagggaa aatcaaaaac agtgagtcaa
    13201 aacccactgt ttatcttctt ttactttaaa ttttttccaa ggccaagcgt aagtcttcaa
    13261 tcaaatcttc tacattttca agaccgattg acagacgaat ttggtttggt gtgacacctg
    13321 ctgcttctag gtctttttct gacaattgac cgtgagtggt tgttgctgga tggacaacaa
    13381 gcgatttagc atctgccgcg tttgcaaggt cagaaaagat ttctaaatta tcaatgacct
    13441 tgcgtgcttc ttcctcgtca cctttgacgt ggaaggtaaa gattgaaccg acaccttttg
    13501 gcaagtattt ctcagccaag gcatgataag gactatctgc aagttttgga taatttacct
    13561 tttctacctt aggatggttg acaagaaaat caacaattgt ctcagcattt tgtacatggc
    13621 gttccacacg aagtgaaaga gtttcaagtc tttgtagcaa gaggaaagca ttgaatggtg
    13681 acaaggctgc acctgtatca cgaagcaatt gaactcgaac agctataata aaggttgctg
    13741 cacccacatc acgaatatag ctcaaattgt ggcagcttga accctcgtca acaaattgag
    13801 ggaatttccc tgaagccgtc cagtcaaaac gaccactatc gacaattatt cctccaatag
    13861 ttgtaccatg cccaccgata aacttagtcg cagagtgaat ggcaatgtca acgccatgag
    13921 agaagacgtt aatcaaataa ggtgttgcaa aagtattgtc tgacacaagt gggatttgat
    13981 gtttatgagc aatctctgcc agtttttcca ggtctggaat attaatcaag gagttaccca
    14041 aggtttcaat caagacaagc ttggtattgt ctttgatagc tgcttctact tcctccaaat
    14101 tatcaatatc gacaaaggtt gttgtgatac cataacgagg aaggggttct ttcaaaagat
    14161 tgaaggttcc accgtaaata gtcgaagcag ccactacatg gtcaccagca tgggcaagcg
    14221 ccaaaatcgt ataagtcact gcagtcatac ctgatgctgt tgctagcgct tcaacaccac
    14281 cttcaagggc agctgttgta ggattggtga tacgagtata aatgttccct ggtttcctca
    14341 aggcaaacag atcagcacct tcctacgtgt catcaaaaac aaaagatgtt gtttgataaa
    14401 tcggcactgc acgagactca gtagctggag tcacaacttg accagcatgt agttgtagag
    14461 tttcaaattt aaaatcacga gtcataaggt gacctccata ttattttatt aaggatattg
    14521 tagcaccttg agttatagtt tacaaatatc agttttctat attttgatat aagaaatagc
    14581 tattacctta ttttgaaaat gaaaaaagca cgactcaatc gtgctcattt tcttaatcta
    14641 cataagtatc ttcgttttta ttgaggaagg catatggaag acccatcaag aggcctcctc
    14701 cgataaagtt tccgatgaaa gtcacacccc agtggcgaag catatttcca acaccgaagt
    14761 tggcaattga atccgcagca acactgaatt tcacaatcgc gaaagaagca aagttcgccg
    14821 caatgtgctc gtttgttaag aatacaaaca tgtaaatagc tgacaacaca agccaaagtt
    14881 tggcaccacc atctttgacc aaaataaatg acagaatcgc aatatttacg aaaatatttg
    14941 ccaaaatcgc ctcaagcaat accaattcat ttgagcggcc taacttcatc tcaacaacac
    15001 ctgagatgaa actatcgtgt gtcagattcg cataggctgc cgaatgagca aagccccacc
    15061 ctgctatcaa ggatccgata aggttgaaca aggtacagta tagtaaaatc tcagctgttt
    15121 ttctccaaga gatttttttt aagaaactac cagcagtcaa gaacatcatg tttgaagtga
    15181 ccaactcggc attcaaaaaa acaatgtagg ccaagcccca agcaaaaacg aatggaaaga
    15241 ggaagcgtcc actacctggt gcaattttat taatcaagtc agccccaact gcacctgcag
    15301 cagtactgaa ggttaaaaat gcacctgcga atatcgaacg aatcgcatac ttaaatttgc
    15361 tttgactata aagactttct ttcttattgc aagcaaattc aatctttgag ataaattctg
    15421 aagaaatcat aataaactcc taaatctttt ttcttgataa ttatatcaca aactttaggt
    15481 tttaggaagc gttttctgta tttcataaaa gtttatagta gattgaaact agaatagtac
    15541 acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgaacga ttagtcctat
    15601 tcttatttca ttttactata tttttatgaa aatcttaaaa aatcagtgaa atccatgatt
    15661 tcactgattt gtattaataa aattgtttat atggttgatt gaaagctgtt aggatttcat
    15721 cagatgtttg tgaataatct tttgtttctt tcaaatcacc tttgacaata atacgttctg
    15781 tagcagcaag gtcttcacag gttactaatg tgatttcatt gaccccatct ctatcatcaa
    15841 cttcatcaac acgatctggt gtcacacgtt tgacttcacg tatttcataa gtataaactt
    15901 tatttttatc agttagataa atcttcatgc catttttagc attatctaaa ggagaaaata
    15961 acattttatt agcattatca acaccaaaga tatggtgact agctagacta taatttcctt
    16021 ctcccattac ttgctcgcgt ttcattgtac cagctccgta gaagagatta acattatcaa
    16081 gtcctttaaa aatcggcaaa ttcatttcca attcaggaat tgcaattccc ccaataactg
    16141 gtaatttttg agcatcccat tgagaagtta gaacagcttc cgaagagata gctttgacag
    16201 aatcaaagtc aaaattgcct tctgtatcct gattttcttc taatttttct tttgatacct
    16261 ggctaacttg atacttattg gtattccaga ctatgaaaat atttcgaatt tgagtattaa
    16321 aaatcaaagc cagtgacagt aatatcagaa atcctgctag gatatttgtc agcagatttt
    16381 ttcgcttgtt tttcttttta ttattttttt gagacattat gcttcacctt ctgtttcgtt
    16441 ttctgtccca acttcttctt tttctgccac cgcaaccgtt gtgaaagtca ctatctgagc
    16501 atcttgatcc aggcgcatta ctttaactcc catagttgca cgtcctgttt gtgaaatatt
    16561 ggcaagattg gttcgaatca tgacacctgt atcagtgata atcatcaaat cctcatcccc
    16621 ttgaacagtc ataagaccgg ccagcaagcc atttttttcg gtaattttag ctgtctgcat
    16681 tcccttacca ccacgacctt ttgttgggta ttcagtagcg actgtacgct taccatatcc
    16741 tttttctgtg ataataagaa cctcatcttg atcagtaatc aagctggcac caacaactgt
    16801 gtctccttca cgaaggttaa cacctttcac accagtggcg atacgactca taccacgaac
    16861 ggctgattga ttaaagcgaa ctgcataacc aaacttggta ccaatgataa tatccatatc
    16921 tccttctgcc aacaagacat tgattaactc atcttcatcc tttaaattca gcgctttgag
    16981 accattttga cgaatattgg caaactcctt aacactagtt ctcttcacaa taccgtgacg
    17041 ggttgtaaag aagagataag catcatcact gcgatcagac tcaacattga taaccgtctg
    17101 aatactttcg tcttcatcca atttcaagag attgactact ggtagccctt tggcagtccg
    17161 accatactca ggaatttcat aacctttaag acgatagaca cgtcccttgt ttgtgaagaa
    17221 gagcagatga tcatgggtgc tagttgacac taactcacga acaaagtcat catctttcac
    17281 tcccgttcct tggacaccac gacccccacg tttttgagca gtgaactcgt cctgatccaa
    17341 acgcttaatg tagcctctgt tagaaagggt aatcaagaca tccgattctt caatcaagtc
    17401 ctcatcctcg agactcaaga cctgtccaat catcaactct gtacggcgct tatcagaaaa
    17461 tttacgttta acttcatcca attcgtcttt gataatttga gaaacacgtt caggcttagc
    17521 aagaatatct gctaaatccg caatcagagc caagaggtca tcatactcag attgaatctt
    17581 atcgcgttcc aaacctgtca aacgacgaag acgcatatca aggatagctt gactttgacg
    17641 ttcagaaagc ttaaacttgc tcatcaactc agcttgagct tccgcatccg tttcactagc
    17701 acggatgata cgaatcactt cgtcgatatg gtctagcgca atcaagagac cttctaagat
    17761 atgagcgcgc gcttccgctt tttccttatc aaaacgtgta cgacgaacaa ccacttcttt
    17821 ttggtgctcg atataagcat ccaaaatctg acgaagagac aaaattttcg gtataccatt
    17881 ttggatagcg agcatattga aaccaaaatt ggtttgcatt tgggtcattt tgaagaggtt
    17941 attgagaata acattggctg aggcgtcgcg cttgacttca ataacaaatc gaacaccttc
    18001 acggtttgac tcatcacgta ctgc
//
