LOCUS       NZ_FEEQ01000004        24177 bp    DNA     linear   CON 04-JAN-2025
DEFINITION  Streptococcus pneumoniae strain 2842STDY5644069, whole genome
            shotgun sequence.
ACCESSION   NZ_FEEQ01000004
VERSION     NZ_FEEQ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900047005.1-RS_2025_01_04
            Annotation Date                   :: 01/04/2025 01:43:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,253
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 86 of 184
            Pseudo Genes (incomplete)         :: 88 of 184
            Pseudo Genes (internal stop)      :: 60 of 184
            Pseudo Genes (multiple problems)  :: 40 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:55:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 96468
            Orig. end                         :: 120645
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FEEQ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24177
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24177
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24177
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14177](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14177)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(449..1822)
                     /locus_tag="A1T31_RS03810"
                     /old_locus_tag="ERS367508_00736"
     CDS             complement(449..1822)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /locus_tag="A1T31_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00736"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_000231787.1"
                     /transl_table=11
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKEV
                     ANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVWTE
                     DPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESASTD
                     LDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIHSSYG
                     GVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEEVSRIY
                     GLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVRLVPGLE
                     PHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYPQGVSVLP
                     TTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVEELIRSYE"
     gene            complement(1922..2776)
                     /locus_tag="A1T31_RS03815"
                     /old_locus_tag="ERS367508_00737"
     CDS             complement(1922..2776)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /locus_tag="A1T31_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00737"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_000694501.1"
                     /transl_table=11
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRSG
                     SEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENG
                     KDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAG
                     LIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYK
                     KALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQ
                     PVW"
     misc_feature    complement(2740..2759)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.25"
                     /tool="antismash"
     misc_feature    complement(2742..2756)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            complement(2930..3760)
                     /locus_tag="A1T31_RS03820"
                     /old_locus_tag="ERS367508_00738"
     CDS             complement(2930..3760)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /locus_tag="A1T31_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00738"
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_000724951.1"
                     /transl_table=11
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVATN
                     GSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAVNN
                     LSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQLEAY
                     NAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVIELPS
                     DQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK"
     gene            complement(3864..>3935)
                     /locus_tag="A1T31_RS12945"
                     /pseudo=""
     CDS             complement(3864..>3935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /locus_tag="A1T31_RS12945"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="AzlC protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RYCNLVGTVLFGVVLIAILRLVF"
     gene            complement(3982..4812)
                     /locus_tag="A1T31_RS03825"
                     /old_locus_tag="ERS367508_00739"
     CDS             complement(3982..4812)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /locus_tag="A1T31_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00739"
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_000724960.1"
                     /transl_table=11
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVATN
                     SSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAVNN
                     ISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQLEDY
                     NKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVIDLPS
                     DQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK"
     gene            complement(4916..5068)
                     /locus_tag="A1T31_RS13745"
     CDS             complement(4916..5068)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017273.5"
                     /locus_tag="A1T31_RS13745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_313959172.1"
                     /transl_table=11
                     /translation="MTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            complement(<5084..5530)
                     /locus_tag="A1T31_RS03830"
                     /old_locus_tag="ERS367508_00740"
                     /pseudo=""
     CDS             complement(<5084..5530)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466402.1"
                     /locus_tag="A1T31_RS03830"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00740"
                     /product="AzlC family ABC transporter permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPTALGYVSIGLVCGIIGVPYVTLVEMGLMSLFVYAGSAQFAMLA
                     LIVVQAPVTAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLMGE
                     LAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFAL"
     gene            5601..5750
                     /locus_tag="A1T31_RS13240"
     CDS             5601..5750
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1T31_RS13240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_001831877.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSNHTYGKVKLTWFEESF
                     EEYK"
     gene            complement(5985..7211)
                     /locus_tag="A1T31_RS03840"
                     /old_locus_tag="ERS367508_00741"
     CDS             complement(5985..7211)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /locus_tag="A1T31_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00741"
                     /product="MFS transporter"
                     /protein_id="WP_061753151.1"
                     /transl_table=11
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLAI
                     LLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLLLV
                     TFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILGGVL
                     LGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQSSKL
                     IWKMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLELSALIL
                     GSLMSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGILSPRLQ
                     ELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLLFLLVAFV
                     MLLNIRESI"
     gene            complement(7283..7948)
                     /locus_tag="A1T31_RS03845"
                     /old_locus_tag="ERS367508_00742"
     CDS             complement(7283..7948)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /locus_tag="A1T31_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00742"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_000720786.1"
                     /sec_met_domain="Abi (E-value: 2.2e-17, bitscore: 56.9,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIISHRYFIIVFLLVIADQKFSALVLRSDLVTGLSDFAYYLSD
                     MMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPPTR
                     NEISYQHAAPTFTGATAFLMYFFYPVIVGPIFEEIIHRGLVMTALEKGKKWGLDVLGSA
                     VLFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLLMLL"
     gene            complement(7960..8637)
                     /locus_tag="A1T31_RS03850"
                     /old_locus_tag="ERS367508_00743"
     CDS             complement(7960..8637)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /locus_tag="A1T31_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00743"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_000738303.1"
                     /sec_met_domain="Abi (E-value: 9.7e-20, bitscore: 64.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMAALSDNMYYVFQ
                     VLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPRTQ
                     NGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVLVSA
                     AIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIVTLLV
                     FGY"
     gene            complement(8716..9972)
                     /locus_tag="A1T31_RS03855"
                     /old_locus_tag="ERS367508_00744"
     CDS             complement(8716..9972)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722643.1"
                     /locus_tag="A1T31_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00744"
                     /product="MFS transporter"
                     /protein_id="WP_000722643.1"
                     /transl_table=11
                     /translation="MKKILNNKLYMKVLVSDLISNFGDTLYFIALMTYVTEIKSSNLAI
                     SIVNISETIPILFTIFFGIIADRTLNKVGMIIKTLWIRTILYLLVAVVMNFKESILVVI
                     LASIVNLISDTLGQFENGLFYPISNRIVKKSDREETMAFRQTATSTMNIVNQSLGAFLI
                     TFLSFFHLALINSLTFAISLLITLAIKSQINNFYIDKTPSTKVSKVDFKATFSDIISNL
                     KLSLKHLFSLTNMKTVLLVIPILNGSLAIIIPLAVVNLSKSSALTIISSATTISVLGIS
                     TVSGGILGGTLILISKKFKNLSIENLLKMNLMTILLSFIAFYYQNIYFIVLTLFLSSVF
                     VSALNPKIGAIIFNNLDETKLATIFGGMVTYFQLGDVVSRLLFSTLVIYLSYTYIAVIY
                     MILVLIVAIYTFRRVQTTS"
     gene            complement(10001..11278)
                     /locus_tag="A1T31_RS03860"
                     /old_locus_tag="ERS367508_00745"
     CDS             complement(10001..11278)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244305.1"
                     /locus_tag="A1T31_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00745"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_001244305.1"
                     /sec_met_domain="LANC_like (E-value: 8.7e-49, bitscore:
                     159.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNIIKKYDEIINKVDSLVLDNNIIDLLQRSCYTENRSYLSEYPS
                     IIIYLSYRLANCDDNEHSKLLYNRVNYYLHELLKSIKLNSRNNISMCYGFSGYVYALKL
                     LPKRSKEYSKLLETLETILVSLTRDRLSEIKKSNKVKEEYIDVIQGVSSVGKYFLSKDK
                     LTSNQELLLKGVLNYLAGVINNKPTIYPEYMPNEKLKRKFPNGYINLGVAHGILGPLYV
                     LALGFKKFNMPEYLISLKKGLSYYEKTFQTNKIGKIIGWNGRVSAEVESEKFEYNLSWC
                     YGSLGMARVLYNISKIIDIPKLQELATDVFHSSIYYLNSSEILNNAICHGRSGIMLLFN
                     LMYLDTGESQFKAISDNLFKEIVNKATDSEYIFVERDIYFRGVNYDEVIEYIDFGLLNG
                     VSGIVLALMAQRTGNASPLAEMFFMQ"
     gene            complement(11262..14177)
                     /locus_tag="A1T31_RS03865"
                     /old_locus_tag="ERS367508_00746"
     CDS             complement(11262..14177)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472732.1"
                     /locus_tag="A1T31_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00746"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_000472731.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.4e-80, bitscore:
                     262.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-08,
                     bitscore: 29.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9e-16, bitscore:
                     51.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKIKDNYIYRQCVNDSILIEKLNENNLEIFFDSKIFQEMLMVAN
                     PRFFNELTKEKIYQNSTFRNYAKRSLTRATPFGLFSSVGVGSFSKVSYPQQIRENYSKK
                     VSVSGEWISSLCMMLENEDSVLLQLHLQWNQKVLELSDKYQLNNINYWGVSEQSRDILI
                     KKTALLEFIKKLTYKSEVSVLDLVQEIQTKSPNLETQKIIDYLRNLIISEFLFTNLRKV
                     VINHNCLDNLIYILSSINEQTKLTTDLLQLKSCIEKYSKSELGEGILQYAEICEKMSHI
                     FNEEKQRYLKVDLVNSYDSLLPKDLKKTLEDFVNFISRINLGKDYRNKELISYTEKFVE
                     KYGEYVEVPIKQLLDSKLGLGIPKQNLEPYSILSSVAEQTFLSYLSKEIFKAVKNNKKE
                     IDISNIPPELLYPNLDRFAVNQFELYCEMKNFGEQPVISIVPNTGSDMIGKSIGRFASY
                     FLNSNIELDSRVDNVELIEFPSDNKNLNVMSSHHGHSKKLLLSYEDDFDIDSLELDFLV
                     VGVERVNEHYKLYFRDLRTDLIVNFVTTSMLNHKSIGVFSHLARFLLTVSLEWQDNPFS
                     LFRVIENLDFLPYIPRIKYKNIILSEEKWILSDVDKKDMSTISQWKKFFDVPSLLYFHK
                     DDERLLIDLKNSLDVQWILKQNVDKLHFTRFDKIDGKNCEFIFGFENPRNSVYPHSVSE
                     KTVRRIENDFYKDYVKTFSSDWIYFKLYGINSSTMPELRENLLIFTDELLAEKLVSDFH
                     FVNYNDGGDGSIRLRFKIMNEDDFEKLRYRIIHWIDFLLNHYFCKDVSFNLYEREVERY
                     GGIGFLTVCERIFSIDSYLVLKLFSKKVLKVDDYLSVLHSIFIYIRLLGISPKQLLKLM
                     KDTFTQNIYRKSFKKVFPNNAKVIKEFKQYFEDQSKFDIFNEVFKSFSPIEKHFEYKND
                     MIHSLLHMHMNRIGIFSLNEKEYLYFVRYILEVLNNYEKYN"
     aSDomain        complement(13515..13715)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A1T31_RS03865_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.90E-09"
                     /identifier="RREFam001.1"
                     /label="A1T31_RS03865"
                     /locus_tag="A1T31_RS03865"
                     /protein_end="221"
                     /protein_start="154"
                     /score="29.1"
                     /tool="antismash"
                     /translation="SEQSRDILIKKTALLEFIKKLTYKSEVSVLDLVQEIQTKSPNLET
                     QKIIDYLRNLIISEFLFTNLRK"
     gene            complement(14237..14341)
                     /locus_tag="A1T31_RS03870"
                     /old_locus_tag="ERS367508_00747"
     CDS             complement(14237..14341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225312.1"
                     /locus_tag="A1T31_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00747"
                     /product="hypothetical protein"
                     /protein_id="WP_000432035.1"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVATEQDYVSSGVTSTGCCKN"
     gene            complement(14632..15495)
                     /locus_tag="A1T31_RS03875"
                     /old_locus_tag="ERS367508_00748"
     CDS             complement(14632..15495)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /locus_tag="A1T31_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00748"
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="WP_061753152.1"
                     /sec_met_domain="TIGR01716 (E-value: 1.5e-67, bitscore:
                     220.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSML
                     SADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEVEQ
                     EQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCNTLP
                     FLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFEAELE
                     SMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLTSLFELRLQQ
                     YKALID"
     gene            complement(15891..17063)
                     /locus_tag="A1T31_RS03880"
                     /old_locus_tag="ERS367508_00749"
     CDS             complement(15891..17063)
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152: nucleotide sugar dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /locus_tag="A1T31_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00749"
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="WP_001017600.1"
                     /transl_table=11
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPS
                     KNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVSKI
                     LRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDE
                     TVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAE
                     RRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDI
                     SNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEP
                     NLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            complement(17076..17825)
                     /locus_tag="A1T31_RS03885"
                     /old_locus_tag="ERS367508_00750"
     CDS             complement(17076..17825)
                     /EC_number="3.5.1.-"
                     /GO_function="GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /locus_tag="A1T31_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00750"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_000069860.1"
                     /sec_met_domain="PIG-L (E-value: 3e-18, bitscore: 60.3,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGYP
                     LSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNGNF
                     LYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALEFMR
                     YKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILIIWKS
                     VEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(17837..18265)
                     /locus_tag="A1T31_RS03890"
                     /old_locus_tag="ERS367508_00751"
     CDS             complement(17837..18265)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /locus_tag="A1T31_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00751"
                     /product="hypothetical protein"
                     /protein_id="WP_001290270.1"
                     /transl_table=11
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTTH
                     LFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIERI
                     LKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     misc_feature    18217..18234
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            complement(<18376..18594)
                     /locus_tag="A1T31_RS13750"
                     /old_locus_tag="ERS367508_00752"
                     /pseudo=""
     CDS             complement(<18376..18594)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818694.1"
                     /locus_tag="A1T31_RS13750"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00752"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRFYCEAYEVITEEKKVYFNDIELEVKYSSVEELFIICEKLLDKK
                     KVSFFYVDEKPLRYLLFDYIFLLVLAKK"
     gene            complement(18614..20230)
                     /locus_tag="A1T31_RS03900"
                     /old_locus_tag="ERS367508_00753"
     CDS             complement(18614..20230)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /locus_tag="A1T31_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00753"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_000288029.1"
                     /transl_table=11
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMNL
                     ERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKS
                     SGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIML
                     LVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLK
                     MVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTA
                     LGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDK
                     EILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNM
                     VSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDD
                     GRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTH
                     APHPELKQYFTKIYQFPKDFI"
     gene            complement(20240..21193)
                     /locus_tag="A1T31_RS03905"
                     /old_locus_tag="ERS367508_00754"
     CDS             complement(20240..21193)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /locus_tag="A1T31_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00754"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_000375722.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-29,
                     bitscore: 95.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIIDD
                     NYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDEYM
                     SDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTS
                     FWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGV
                     TQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAR
                     EEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            complement(21186..21710)
                     /locus_tag="A1T31_RS13245"
                     /old_locus_tag="ERS367508_00755"
     CDS             complement(21186..21710)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.5"
                     /locus_tag="A1T31_RS13245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00755"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_000371189.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-29,
                     bitscore: 96.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHL
                     KCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEI
                     IEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRV
                     YDELLEKSSHG"
     misc_feature    21662..21676
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.61"
                     /tool="antismash"
     gene            complement(21838..22392)
                     /locus_tag="A1T31_RS13250"
                     /old_locus_tag="ERS367508_00756"
     CDS             complement(21838..22392)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024831.5"
                     /locus_tag="A1T31_RS13250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00756"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_001810713.1"
                     /transl_table=11
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHII
                     GLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILKLL
                     KIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYSM
                     GDAFICVSETMKKRLESIIKK"
     misc_feature    complement(22346..22361)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            <22635..>23326
                     /locus_tag="A1T31_RS13255"
                     /pseudo=""
     CDS             22635..>23326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /locus_tag="A1T31_RS13255"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGYSLK
                     KSCTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVETYFYLEYDRALSRQLVSLEEDI
                     II"
     misc_feature    complement(23893..23902)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.28"
                     /tool="antismash"
ORIGIN
        1 ccctccagat agttgtgaag ggtagttttc agcacgatct gccaaaccaa ccaagtccaa
       61 caacttagct actttagcct tcttttcttc cttgctgagt ccagagtgtt taagggcaaa
      121 ggctacattc tcctctgctg tcttttggct catcaggtta aaatgctgga aaatcatccc
      181 gatatcttga cgtttacgac gcaactgctc tgccgtcaag gtcaccttgc cgtcaaaaat
      241 cacatcgtcg tcaatggtaa ttttccctgc agatggtttt tgcaagagat taatcacccg
      301 tacaagggtt gatttccctg ctccagaata tccaacgatt ccgtagatat ccccttcttg
      361 gatgtgaatg gtcacatcct taaccgctgt gatggttctc ttcttttggt gaaaagtcac
      421 atcgatctga tctaacttga taatatctct actcatagct tctaatcagc tcctctacta
      481 attcgatatg ggtgtaataa tcagcgattc gcacattttc atctccaccg tggtctcggc
      541 tattggcatt tcctagaccg aatgcaacca ttggtacctc tagggcatca aagaccgtat
      601 gcataggtcc tgtccccgct gtcgtcggca agactgaaac gccctgtgga tagaatttct
      661 tggccaactc gatcacattg agaatggctg gtgcgctcat atcgcttcga tagctcatct
      721 ctcccaaggt atagtataat tctaccttat caaagccatt tttgtctagc tgtttccgaa
      781 ttttttccag aacatcatgc ggttctagac ccggaaccag acgaacctct agcttggcac
      841 tggcttctgc aggcaaaata gtcttaacac cctgaccttg ataaccagac tggattcctt
      901 cgatattaag cgctggctcg aaaaagaaac gttttagaaa ggccatccgc tcctcctgta
      961 agagaggcaa ctccaatcca taaatccgac taacttcctc tgggtttcgt tgaccataag
     1021 tttctagcaa ggccatttct cgttcattgg gctcttgtac ttcttcgtac aagccttcaa
     1081 ccaagatacg gccatccgca gcacgaagag actgtaaggc ttggaggaga taccaaggag
     1141 ctgattccac aacaccacca taactcgagt ggatatccac atcagcgctt tttaccttgg
     1201 catcaaaggt cacaatcccc ttattgccac cagaaatttc cagctgttcc aaggcatttt
     1261 tggtcccttg ttcccagacc aacaaatccg ccccacggag tttgtctgca tgcttttcca
     1321 aatacttatc taggtctgtt gaagccgatt cctccgctcc ctccatgata aagctgatat
     1381 tgacaggtaa atcatcatgg tgctgcatat attttctcaa agcactcaag cgagctgtga
     1441 tatgaccctt gtcgtcatca accccacgcc catacatgaa gccattgcgg accgaaagcg
     1501 taaaaggatc ctctgtccag acctgatccc catccgctgg cacagtgtca tagtggttat
     1561 agaaaatcaa ggtcttggca tctggacgcg aactcttgaa atgtgccatg acaaagggag
     1621 ctgtatagct ctcatcaatc tccacttcag ctccaacacg cttgaaaatc tcacccagat
     1681 aatttgcgac ttccttgagt ccaacctgct gggcaaagac tgatttctta gaaatcaagg
     1741 tacgcaaaac ctcaaaataa tgctgggcta catgatcctt ttcaaatttt tcaatctgtt
     1801 cttgttcgct aggaaaaacc atattctctc tacctttcta tgaacgaata gtcttcttta
     1861 cactccgtgc tctatacaaa agcaagaggt ggaattctct ctcccacctc cctgtttctt
     1921 attaccaaac tggttgatcc aaaccgtctg atgattcttc gataactttt ttcacgtcat
     1981 ctgtgtggta agctgcgatt actttcttga tagcatcagc cttaggtgat gtttcccaat
     2041 cttttttcgc aacaatgatg ttgtaccatt gttttgagtt ttcatcagct tgttctttga
     2101 aaagtgcttt cttgtagtcc aattttgctt ctgtaacgaa ggtattgttt acaacggcag
     2161 cgtcaactga tgacaatgaa cgagctgttt ggctagcgtc caattcagtg attttcaagt
     2221 tctttggatt ttctttgatg ttggcaactg ttgcaagagc agttccagaa acatccaatt
     2281 taatcaagcc agctgattga agcaagtaaa gcgcacggct ttcgtttgta gcgtcatttg
     2341 gtacagcgat ttctccgttt gctgggatgt cttctacttt agtgtacttg ttggcacttc
     2401 cattcaaacc tgagtaaagg cggattggag agatgtaagt atctgcaatc gctacaaggt
     2461 cttttccgtt ttctttgttc cagttgttca agaagttata gtgttggaaa gcgttcaaat
     2521 ctacttcgcc atcagcagtt gctttgtttg gttgtgagta gtctgtgaac tctgtaaatt
     2581 ccaaggtaat tccgtctttt ttaaccaatt cttggatttt gtcccaacgt ttttcttcag
     2641 aaccgctacg gttaacagtt gcgattttga tagttgttgc attgtctgct ttcttttctg
     2701 agtttccgca agctgcaaga gccaaacctg cgactgtagc aagggctgct aggccaagcc
     2761 attttttgat tttcatgatt ctttctcctt aaaaataata ccgtactagt atctcacaat
     2821 ttgtttgatt tcacaaattg ttattagata gtcagatata tagtttaaaa ctatatccct
     2881 aaaaactgag aaaccaccca ccttactcag aatggatgat ttcaagaaat tatttaatat
     2941 cagcttctgc cggtagataa gtgtctccga agaattgttt agacaatttt tcaagagttc
     3001 catctttata aagttctttg atgcgtttgt ctacaaatga tttcaactca tcttgacctt
     3061 gagcaagaag tgggtaaacg tacggttgtt ggtcgcttgg aagttcgata actttcaagt
     3121 tgtccaaacc ttggttcttg atcactgttt caacaccgat tttatcaaaa atcttgtagt
     3181 caaattgtcc atcgctcaaa cgtaccatga tttgttggaa gtctgcctta gtatagttaa
     3241 ggatagttgg gttgtccgtg tgttcagcat tgtatgcttc taactgctta gctgatgtag
     3301 tggcttgaac gacttccgtc gattttccac cgatatcatc gagagacttg atactagagt
     3361 catctttctt cacgacaagg acattaggat tttgggcaat tggtgcggca tagaggtatt
     3421 tctccgcacg ttctttagtg tagctaagat tgttgacagc catattgtaa cggtcagcgt
     3481 caagaccagc aaagacacct gaccattctg tcttttcaaa cttgacatca tatttgtcag
     3541 aatctttaaa gatagcgcga acgacttcaa tctcgtaacc agtcaattcg ccattttctt
     3601 catagataaa tggccttggt gatccattgg ttgcaacgat gatttctttc ttgctagctg
     3661 cttctccttc tttcttagca ccacctgagc aagccgcaag cacacctgca gcaacaagtc
     3721 ctagggcagc aagagatgag tatttaacga tttttttcat gtcatttcct ccaaaataga
     3781 ataccttata atcttaacag aaaaagagca tttacgccat tatatgatat ctatctctgt
     3841 gataagtttt ttttatgggt aatttaaaag accaaacgca agatggcaat caagaccact
     3901 ccaaagagaa ctgttccgac tagattgcag tagcgaactg aaaaatcacc catcttactc
     3961 agaatggatg atttcaagaa attatttaat atcagcttct gccggtaggt aagtgtctcc
     4021 gaagaattgt ttagacaatt tttcaagagt tccgtctttg tagagttctt ggatacgttt
     4081 gtctacaaat gttttcaact catcttgacc tttagcaaga agtgggtaaa cgtacggttg
     4141 ttggtcgctt ggaagatcga tgactttcaa gttgtccaaa ccttggttct tgatgactgt
     4201 ttcaacagtg attttatcaa aaatcttgta gtcaaactga ccatcgctca agtggcccat
     4261 gatttgttgt aagtttgctt tagtatagtt aaggatagtt ggattatctg agtgttgttt
     4321 gttgtagtct tctaactgtt tagcagatgt tgttccttga acaacttctg ttgattttcc
     4381 accaacatca tcaagcgatt tgatgctaga atcgtctttc ttgactacaa gaacgttagg
     4441 gtctttaaca gttggggctg cataaaggta tttctccgca cgttctttag tgtagctgat
     4501 attgttaaca gccatttggt aacggtcagc gtcaagaccc gcaaagacac ctgaccactc
     4561 tgtcttctca aacttgacat catacttgtc agagtcttta aagatagcgc gaacgacttc
     4621 aatctcgtaa ccagtcaatt cgccattttc ttcatagttg aatggttttg gtgaagaatt
     4681 agttgcaaca ataatttctt tcttgctagc tgcttgtcct tctttcttag caccacctga
     4741 gcaagctgct agcacacctg cagcaacaag ccctagggca gcaagagatg agtatttaac
     4801 gatttttttc atgtcatttc ctccaaaata gaatacctta taatcttaac agaaaaaaat
     4861 catttacacc attatatgat atatatatct gtgataggtt ttctttatgg ctgatttaaa
     4921 agaccaaacg caagacggca atcaagacta ctccaaagag aactgttccg actagattgc
     4981 ggtagcgaaa ggctacccaa gctgttggaa agacggctaa gaagtctagc catttaattt
     5041 gaggaaggct cccaacctta cctgtcacta cgcttgaaag aatcaaggca aagatttctg
     5101 gatttggtag caggccaccc agagccgttc cgactactgt ccccacaaac caagccacat
     5161 agctgttaag attgtttccg tgcatccaca taggatttac cttgtctgta tgggctaatt
     5221 cgcccatcaa aacgccatag gtctcatctg tcaagatact agacataccg atattgtacc
     5281 aaagactggt atgacggaaa taagtcgatg cgtgtaaact caacaaaaag agacgcaagt
     5341 tgattagaaa aaccgtcata gcaatagctg tcacaggagc ttgaaccaca atcagtgcca
     5401 acatggcaaa ctgggcactc ccagcataaa caaagagact catcaagccc atctcaacaa
     5461 gtgtcacata gggcacaccg ataattccac agaccaggcc gatactgaca tagccaagag
     5521 ccgttggcat ggctgcctgc gccccctcct aaaatccttt ttctttcatc tttctcctca
     5581 tattgtctta ataatactca atgaaaatca aagagcaaac taggaaacta gccgcaggtt
     5641 gctcaaaaca ttgttttgag gttgtggata gaactgacga agtcagtaac catacctacg
     5701 gcaaggtgaa gctgacgtgg tttgaagaga gtttcgaaga gtacaagtag gctgaaaaga
     5761 atccagccac agcatggact attatatagc agattgaaat aagatgagaa caaatcgatt
     5821 gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta ttttagattc
     5881 agtctactat aacacattca gaaaagagaa aaaagtctgt tgattttgac catcataaaa
     5941 agactggcaa tccagtctca aacatatttt atagaaattc tccactaaat actttcacga
     6001 atattcagaa gcatgacaaa ggcaactaga agaaatagca ataaaacaaa gctaactgcc
     6061 agagttccaa agctggtagc aatggttacc aaagctattg taaataagct aggtaagaca
     6121 accgtaatgg caccgataga agattgaact gctcccattg actcctcagg tatttgttta
     6181 aagacgagtt cttgcaatct aggagagaga atacccgcga aaaaggcatc caaggtacta
     6241 aagatgagaa tccagtcaaa acgaactgtg gcaaatccta ctagaagaag caactggata
     6301 acaagtgagg catagagagc tgtttttatg gaaatggtat gttgcagata gccactcata
     6361 agacttccca aaataagggc tgataattct agtgtggcta acaaggcaag agattgacca
     6421 gtttgtaaat tcaaaaaggg ctggttcctt aaaaatagag tggaaatagg aaccgtaaca
     6481 tttatcactg cttgactagt agagataata aacaaaacca agagcacctt attcatcttc
     6541 catatcaatt tcgatgattg gagcaaatgc tggcaaaagg attttacaga gagtccttct
     6601 tgatagctaa tcgttttttc tactttcaag aggtcagttt ttatgaagag gatacctaaa
     6661 aatgcgatta aaaaggtaag agcgttcagt aaggaaataa actggatgga tagaatgcct
     6721 agtaagactc ctcctaggat attactgatt gttttcacta aactaacagt tgactgttta
     6781 aatccaatag cttctgccag atggtcttgc ccaataattc taatgaaaat cggagtgagc
     6841 atggcgcctg aaaaataact caatgtgtca gacaagaggt taagcagaca aataaaggtt
     6901 actagcaaca aggaaaaaga ctgccctgaa agcgataggg acactataga gtaaagcaaa
     6961 aattttgtaa aactaatgac tgtgtatttc aagacacgat gatgttgaaa atccgccaaa
     7021 actcccagaa agatttgtag aacttgggga agggtttctg aaatcgtgat aagtaaaatc
     7081 gccaaagggg caaaagacgc atctgccaca taattcagga aggccagata aaaaatcgta
     7141 tccccaagcg ttgaaatcca ctggttgata gttaattgcc taaaatctct attttgaaga
     7201 aatactttca tcacaactcc ttcttaagtt caaatgggaa tctttcccca gaaatagacc
     7261 gcgatactac taacaaccaa aattacagta acatcaaaag ctgaccaata ccgttgtaga
     7321 ctatatgcag cccaataggc caataaatgg actttgtcat tctaaataag actgcaaata
     7381 taagtccgcc acccatatag acgaaaaagt ctgtcaagac ccaaccgtga ttactaatgt
     7441 gcgagacccc aaataaaaca gcggaaccaa gtacatctag cccccatttc tttccttttt
     7501 ccagagctgt catcaccaat ccccgatgga ttatctcttc aaaaatggga cctacaatca
     7561 caggatagaa aaaatacatc aaaaatgctg tagcccctgt aaaagtcgga gcagcatgtt
     7621 gataagaaat ttcatttcga gtaggtggga aaagaaaaaa ggtaacgaaa ttccaaacaa
     7681 caaaagcaag cagagctagg aaggaataga aaagatagga tcctttaaac tttctactat
     7741 tgattttctg ccatttcccc gaccaaatca tagcaataag agcaaataaa accacaagaa
     7801 aattcaacat catatccgac agataatagg caaagtcaga tagcccagta acaaggtcac
     7861 tgcgtaaaac tagagcactg aacttctggt cagcaataac tagtagaaaa actataataa
     7921 agtagcggtg tgagattatc tttttcatat atcacctttc taatatccaa ataccaataa
     7981 agtaacaatg agtaagaaac tattccatga agcatgcaga gctatagccc aatagatgga
     8041 tcgggtgtag cgaaacatca tacaaaatat caagcccatt ccaaaatact ttatgaaatc
     8101 tgtcgttatc caaccatact gcaaaacatg catagcgcca aatatggcag cggaaacaag
     8161 aacatcaaga tagtatctct taactttaga taaacttgtc atcaaaagac cacgacaaac
     8221 aacctcttct gatacaggtg cgataatact agtataaagt attcgcgtaa caaaatagct
     8281 aattcctgtt aaattggtgg ctacttctac gactgtactt ccattctggg tacgaggaaa
     8341 gatataggtt gttagatttg cccacacgaa caataagaaa aaagaaagaa ggaaaacacc
     8401 caggtaagac caacgaaact ggaaacgacc acactctttc caatgttcac ttttgacaaa
     8461 agcaattgta gctatagttc ccagaataag taccaataaa acttggaaca catagtacat
     8521 attatcagac aaagcagcca taaaatctaa gtctgatgtg acattaaaaa tgaggtaata
     8581 agtcaaaatc aacaagccag ttgctaggtg aaatttcact tctttcattt tcttcatcct
     8641 attatctcct ataagagcct attttatatc taattgcaag gactggagga ataaagttaa
     8701 aatttcaaaa ttctctcagc ttgtagtctg tactcttcta aaagtataga tagccactat
     8761 taaaactaat atcatatata tcactgctat ataagtataa gataaataga ttaccaatgt
     8821 agaaaacaat aatcttgata cgacatctcc caactggaag taagtaacca ttcctccaaa
     8881 tattgtagct agtttcgttt catcaagatt attaaatatg atagctccta ttttaggatt
     8941 taatgcactg acaaatacac tcgaaagaaa taatgttaat actataaaat aaatattttg
     9001 gtaataaaac gcaataaatg ataataaaat agtcattaaa ttcattttca ataagttctc
     9061 tatggaaaga tttttaaatt ttttactaat tagaatcaaa gttccaccta aaatccctcc
     9121 agaaacagta ctaattccca aaactgaaat tgttgttgca gaactaataa ttgtaagagc
     9181 agaactttta gaaagattca ctacagctag tggtatgata atggctaagc tcccattaag
     9241 aattggaata acaagtaata cagtcttcat attagtgaga ctaaatagat gtttaagcga
     9301 aagttttaag tttgaaataa tatcagaaaa cgtagcttta aaatcaactt ttgaaacctt
     9361 agtggatggg gtcttgtcta tataaaaatt gttaatttgg cttttgatag ctaatgttat
     9421 tagtaaacta atagcgaatg ttagagaatt tataagagct aagtgaaaga aactaagaaa
     9481 agtgattaaa aatgccccta acgactgatt tacaatgttc atggtagaag ttgctgtttg
     9541 cctaaacgcc atggtttctt ccctatctga ttttttcact attcgattag aaattggata
     9601 gaaaagacca ttttcaaatt gccccaatgt atctgaaata agattaacta tactagcaag
     9661 tattactact aaaatggatt ccttaaaatt catgacaaca gccactaata aatataaaat
     9721 tgtccgtatc cataacgttt tgataatcat tcccacttta ttaagtgttc tatctgcaat
     9781 gataccaaaa aatattgtga acaatatagg tatagtttcc gatatattta cgattgagat
     9841 agccaaattg ctactcttaa tctccgtcac ataagtcatg agagctataa aatatagtgt
     9901 atctccaaag tttgatatca gatctgaaac caagactttc atatatagct tattatttaa
     9961 aatttttttc atatgttatc cctatatcta ccttaaaccc tcactgcata aaaaacattt
    10021 cagccaaagg agaagcattt cctgtcctct gcgccattag tgcaagaact atcccagaaa
    10081 ccccatttaa caagccaaaa tcaatatact ctatcacttc atcataattc acacccctaa
    10141 aatatatatc acgttccaca aatatgtatt cagaatcagt ggctttattt actatttcct
    10201 taaataaatt atcagaaata gctttaaact gtgattcccc tgtgtctaaa tacatcaagt
    10261 tgaacaaaag cattatccca gagcgaccat gacaaattgc gttatttaaa atttcactac
    10321 tattaaggta ataaatagat gagtggaata catcagtagc taactcttgt aattttggga
    10381 tgtcaattat tttagatata ttatatagta ctcttgccat tccaagacta ccataacacc
    10441 aacttaaatt atattcgaat ttctcacttt ctacctcagc acttactcta ccattccagc
    10501 caataatctt gccaatctta ttagtttgaa aagttttttc atagtaactc aaaccctttt
    10561 ttagcgaaat taaatactct ggcatgttga attttttaaa ccctaatgct aaaacatata
    10621 gtggtcctaa tataccatga gctacaccta ggttgatata gccattgggg aattttctct
    10681 ttaatttttc atttggcata tattccggat aaatagttgg cttattattt attactcctg
    10741 ctaaataatt taaaactcct tttaataata gttcctgatt agaagtcaat ttatccttgc
    10801 taagaaaata ctttcctaca ctagaaactc cttggattac atcaatatat tcttctttaa
    10861 ctttattgga tttttttatt tcacttagcc tatctctagt taaagatact aaaattgttt
    10921 caagtgtctc tagcaattta ctatattctt tactcctctt aggtaacaat ttcaaggcat
    10981 atacatagcc agaaaatcca tagcacattg atatattatt acgactgttc aacttaatcg
    11041 actttaacag ttcatgtaaa tagtagttta ctctattgta gagcaactta gaatgctcgt
    11101 tatcatcgca attagctaat ctatatgata aatatatgat tatgctgggg tattccgaca
    11161 agtaacttct attttccgta tagcacgagc gctgtagtaa atcaataata ttattgtcta
    11221 acactagact atctacttta ttgatgattt catcatactt cttaattata tttctcataa
    11281 ttatttaata cctctaaaat atacctcaca aaataaagat attccttttc atttaaggaa
    11341 aatattccta ttctattcat gtgcatatga agcaaactat gaatcatatc atttttatat
    11401 tcaaaatgtt tctcgatagg tgagaagctt ttaaaaactt cattgaaaat atcaaattta
    11461 ctttgatctt caaaatattg tttgaattcc tttattactt ttgcgttatt gggaaacacc
    11521 tttttaaaac ttttacgata aatattttga gtaaaagtat ccttcatcaa tttaagtaat
    11581 tgttttggag atattcccaa tagtcggata tatataaaaa ttgaatgtag aacagataaa
    11641 taatcatcaa cttttaatac tttctttgaa aacaacttta aaacaagata actatcaata
    11701 gaaaatatcc tctcacatac tgttaaaaag ccaatacctc catatctctc aacctccctc
    11761 tcatataaat taaaacttac atctttacaa aaataatgat ttaataggaa atctatccaa
    11821 tgaataattc gatatcttag cttttcaaaa tcatcttcgt tcataatttt aaaccttaat
    11881 ctaatagaac catccccgcc atcattataa tttacaaaat gaaaatcact aactaatttc
    11941 tcagctaaaa gctcatcagt gaatataaga agattttctc ttagttcagg catcgttgag
    12001 gagttaattc catataattt gaaatatatc caatcgctcg aaaacgtttt tacataatct
    12061 ttataaaagt cattttcaat tcttctgaca gttttttcac ttactgaatg agggtataca
    12121 ctatttcgag gattttcaaa tccaaagata aactcgcaat ttttaccatc aatcttatca
    12181 aaacgcgtaa aatgtaattt atcaacattt tgttttaaaa tccattgaac atctaaacta
    12241 ttctttaggt caatcagtaa acgctcatca tctttatgaa agtatagaag gctaggtaca
    12301 tcaaaaaatt ttttccactg actaatagta gacatatctt ttttatcgac atctgataaa
    12361 atccacttct cttcacttaa aataatattc ttatatttaa ttctaggaat ataaggaagg
    12421 aaatcaagat tctcaattac cctaaataga gaaaatggat tatcttgcca ctctaacgaa
    12481 actgttaaca aaaatctcgc taaatggcta aaaactccga tagatttatg attcagcatt
    12541 gaggttgtta caaaattaac aatcaagtct gttcgtaagt ctctaaaata tagtttgtaa
    12601 tgctcattca ctctctcaac acccactact aagaaatcta attctaacga gtcaatatca
    12661 aagtcatctt cataagatag taataacttt ttagaatgtc catggtgaga agacataaca
    12721 tttaaatttt tattatcact tggaaattct attaattcta cattatcaac cctcgaatct
    12781 aattctatat tagaatttag aaaatatgaa gcaaatctac caatagactt tcctatcata
    12841 tcactcccag tatttggcac aattgatata acaggttgtt ctccaaaatt cttcatttca
    12901 caatacaact cgaactgatt cacagcaaat ctatccaaat ttggatacaa taattcaggc
    12961 ggaatatttg atatatcaat ttccttttta ttatttttca ctgctttaaa gatttcttta
    13021 cttagataag acaaaaaagt ttgttctgca acacttgata atatactata aggttccaaa
    13081 ttttgttttg gtatccccaa ccctaactta ctatccagta gttgcttaat aggaacttca
    13141 acatactctc cgtatttttc gacaaatttt tctgtgtacg agattaattc cttatttcga
    13201 taatctttac ccagattaat tctcgaaata aagttaacga agtcctccaa tgtctttttt
    13261 aaatctttgg gtaatagcga atcataacta ttcactaagt caaccttcag atagcgctgt
    13321 ttttcttcat taaaaatatg agacattttt tcacaaattt cagcatattg aagaatacct
    13381 tctcctaact ctgattttga atacttctcg atgcatgatt taagttgtaa caaatcagta
    13441 gttaattttg tttgctcatt aatagaactt aaaatataaa ttaaattatc taaacaattg
    13501 tgatttatta caacctttcg taagtttgta aataaaaatt cactgataat taaattacgt
    13561 aaataatcaa taattttctg tgtctccaaa ttaggagact tagtttgaat ttcttgtacc
    13621 aagtctaata cacttacttc cgatttatat gtcaattttt taataaattc taaaagggca
    13681 gttttcttga taagtatatc tctactctgc tcggaaacac cccaatagtt gatattattc
    13741 aattgatact tatctgatag ctccagtact ttttgattcc actgtaaatg taattgcaat
    13801 aaaactgaat cttcattttc taacatcata caaagcgaac taatccactc tccactaaca
    13861 gacacttttt tactataatt ctctctaatc tgttgagggt atgaaacttt tgaaaaagaa
    13921 ccaacaccaa ctgaactaaa caatccaaat ggagttgctc ttgtaagcga cctctttgca
    13981 taatttctaa acgtagaatt ttgatatatt ttttccttag ttaattcatt aaaaaatcgt
    14041 ggattcgcca ccatcaacat ctcttgaaat attttgctat caaaaaatat ttcaagatta
    14101 ttttcattaa gtttttctat cagtatagaa tcattaacgc attgcctgta aatataatta
    14161 tcttttattt taaacatatt tttcttttaa ttaaaaagca agtacttgta cctgctttat
    14221 aaaatcaatt attaaattag tttttacaac aacctgtaga tgtaacacca ctagaaacat
    14281 aatcttgttc agttgcaact tcagtcacat caagttccaa tgaaaattct gtattttcca
    14341 taataaacga ttcctcctcc aattattttt acttataaac cacttctgcg acctaggatt
    14401 tgcttcaagt gctttataag tacagtataa cacgaaaatt ggcttatttt agaaaatcgc
    14461 atatttgata ttttttctta taaaaatttc acatttgcga ttttagtaga tttgatcatt
    14521 tccctggtat aataaagtta ttactaatga ggagtggaag tcatatgaag aaacaagttt
    14581 taacattatt gacaatcgtt gctgagatta ttatcttttt cccatttcta actaatcgat
    14641 aagtgctttg tattgctgta agcgtagttc aaaaagggat gttaattgtg gattttctaa
    14701 tacttgcaga gattggataa agtgttcaat ctctttttga ttgcttccct tagtttgaag
    14761 gaaaatgctc atcttcttta aaaactgcca caacactttc tcaaaaacat cgtatggacg
    14821 gagcatactc tccagctcgg cttcaaagat tgggatataa gaaaaaagtt tgcgctccat
    14881 gagctctgag atgatattta agagtccttg cttcatatac aatcgattgt gtactaactc
    14941 tttaaattct ttggattttt cgagtaagga ggttgataaa aagatcagat cttgattgct
    15001 caagaagggc agagtattgc aaaagagata gagttcaaac caggtccaag actcgatagc
    15061 atagagatag gtggtcaaaa actcgctatc ctcctctgct agtgggtagc ttttatctag
    15121 tgagtggatg gcatctttga ttacaatagc attcaaacga cgataagtct ctgccatctg
    15181 ttcttgctcg acttcctcca acagttgctc taagccagct atatcttgat gagcaaagcg
    15241 atccacaacc tttctaccaa tctgcatatg tggagattct tgatagttgt tgagcttgtg
    15301 cccaaactca tcaaaggtca cattgatccc ttggatggct aatatgagct tatcagcaga
    15361 caacatggac tgccctagct caaacttgga caactgagaa gctgttagcc cgtcacaagc
    15421 cacatctgac tgcttgagct ttctcgccaa acgtaattcc ttgtaaaatt cccccaattc
    15481 cattttttca atcatcctac cacctcctag cttttgcata ttatatcatt atttgtgttc
    15541 atttgtcaaa atattctgat agttagaaaa aataaaaaag ccagccttaa gctgactcta
    15601 aaaggaccga gccttgtaca atacagaact caatcctcgt tctaaataga atgtctaact
    15661 tttttgggca gtacacgagc ttggggaaca gccactggaa cgatgaggtg tgagctcaaa
    15721 atatcctcca gttatgtttt tcctaatagt ataccggaag agtgaaagga ttttataatg
    15781 gagcggttac aaagaaccta ctttctatta aacagtatac tatgaaaatg tgaaaattta
    15841 acattttttt gtacaaattt tataaattat tgccttttta atatcaatag ttaatctctt
    15901 atccagatcc cccttgtgta aactttatct ttataagctt caaggcccct atcccatcta
    15961 tttgcaacaa ttagatcact ttgttttgta aatagttcaa aattcttttc aaaaattacg
    16021 ttatctatac taacgtttaa atttggttca tatactaaaa tttttatacc gacaatcaat
    16081 agttcattaa ttatacttaa aatagctgac tctttgtaat tatctgaatt atatttcatc
    16141 cccaatttat atattcctac tatctttggc tttcgttcca atatttgttt aactatgaac
    16201 tgttttctat ttgtgtttga aatatcaatc gcttctatca ctggggcatt tatttctata
    16261 aattcttttt ttaattgttt agtatctttg ggaagacaat atcctccaaa tccaaaagaa
    16321 agattattat aaaaatttcc aattcttgga tctaaacaaa caccttttat tacaacttca
    16381 gcatttaaac ttctcctctc agcaaaagaa tctagttcat taaaaaaagc aacacggaga
    16441 gctaagaatg tgttagaaaa aagcttaatt gcttctgctt cagtaggaga aactaacata
    16501 acatttttaa tattggcagt actatgagta ctaatcgaaa ggaacaactc tgcaattttt
    16561 cttccttcaa ctgtctcatc tccaacaact atgcgacttg gatataaatt atcatatata
    16621 gaacaacctt ctctcaaaaa ttcagggaca aaaatgatat tttttgtatc aaacagcctt
    16681 tttaatttgt ttgaaaagcc gaacggaact gttgacttta aaataatctt tccattaggt
    16741 tttaccctca gaatcttcga taccgtttgt tcgatttcat atgtattaaa actaccaatt
    16801 ttctcatcat aatctgtcgg aagcgcaata atataataat caatattatt tttaatttca
    16861 gaaaatgtat caaaaaaagt aatatttaag ttattctcgc aaaaaaactt cataagctct
    16921 tcatttttag atggaagaat gccctttttt aaattattta tttttacaga atctatatca
    16981 tatgcaacaa ctttatattt agatgcaaat agtaacgcgt aggccagccc aacatgcccc
    17041 aaaccaatta ctgctatatt cataaaacta cttccttatt tcttaatcca aaatctaata
    17101 gaataagctg ccccattcct taaatacaac tctttaatat tgtttaaaag tttttcaact
    17161 gatttccaga ttatcaaaat ctgagattta tagcacaata ttgatgatat tctatcaata
    17221 taatgttttt catcaagttc ctcttgatac atttttaatt ctttagtttt tcccatataa
    17281 ctaaccatac tactatcact tacatatggg aagtcctcat aatatattac tttataacgc
    17341 ataaattcaa gcgcccttcc aatactattc acaaaaacat gatcaacatg gtcaccaagt
    17401 gaaagcggac aatatacgac acatttgtcg tctaaatgca ttaacagctc ttttatgata
    17461 tcattcttta atgtgtcctc attttttaat tcactataga tatgacggta tagaaaattg
    17521 ccatttctat ctttcctata gagacattca tagtacgata agtgtctaaa atcacactgt
    17581 agacgttcac aagctaacct gtcttctttc ttcctttctt caatcggata tttcccaagg
    17641 ttacacaact tatgaaattg cttagcagag ggctgtagct gttggctcaa agggtaacca
    17701 gaaaatatag taataacaag tacaatttct ccttctgaag ttaattttga aatataatca
    17761 ccacaggaaa aaattgcgtc atctaaatgt ggagataaaa agatatactt agtattgtta
    17821 ctcataacca ttccctctac aatttatcta aaaactcact aagtgtctga ttaaattcca
    17881 catcatcaaa aaaattcacc ttattcttaa taatgaatat ttcgttaaat aaacatatat
    17941 ataaatattt caatatcctt tcaatatcat cctctaaatt ctcctcaata ttttgtatca
    18001 gcccatttac aatcttatta aaaaagataa gctctttatc tctaaaatta aatattttca
    18061 tacaactgtt gtatcgaaaa atatataaaa taatttttac taatgtttga atatttaaac
    18121 aactaaataa atgagttgta ctcgggacac tatttatgtt atcaagaaca ctatcttgaa
    18181 acctcaactc acagttcttt ttgtgaaatt cttttttatc gtttagatct gatatttttt
    18241 tagacatttc aacaatctca gacattttat atggatatct aggatgaatg ccaaaactat
    18301 gcaaaatgaa ctgcacccca aaagttagac agaataaatc taacttttgg ggtgcagttc
    18361 ataagattgg gatatttttt tagctagaac tagtagaaat atatagtcaa ataacagata
    18421 ccttaagggt ttctcatcta cataaaaaaa tgatactttt ttcttatcta ataatttctc
    18481 acatattata aacaattctt cgacagagga atacttaact tctaactcaa tatcattaaa
    18541 gtatactttt ttctcttcag taattacctc ataagcttca caatagaatc tcatgtttcc
    18601 ctcccctata ttcttaaata aaatcctttg gaaattgata tatcttagta aaatattgtt
    18661 taagttccgg atgcggagca tgggtaacaa taatgacagt caaatcctct ctatctaata
    18721 tcttacgttc aatcgctaac gaagttctcc tatcgatagc agaagttccc tcgtcaatta
    18781 atactatttt cttatttcta attagccctc tagctaaagt aattttttgt ttctgccctc
    18841 ctgacagtaa tctcccatca tcaccaacat aataatctaa aatgttatta ggaaaatctt
    18901 ttacactcaa accaacttgc tctaaagact gtagtatttc ttcatcagta taattttctt
    18961 ccaataaaat attatctcta atcgtacctt caaacaaata agctttttga tctacatata
    19021 gaacattcga aaccatattt aaataggagg ttttttttat atcatccccg cagaatcgca
    19081 attctccact ataatctctc aaaaagccat tcaataattt taataatgta gatttcccgc
    19141 ttccactttc acctaaaatt aaatactttt cattacgttg aaaacaaaaa tttaagtttt
    19201 ttaatatttc tttatctcca tacttatagc aaatattttt tgcttcatat aacggaaaat
    19261 ctctattcac ctcatttggt tcgatatcat tcattttatt tgactcaatt ggattaattg
    19321 aatacaattt taaaaaaata ggcttcgtac caataataga ggataattga cctcctaatt
    19381 cacctagcgc tgtaaaaata acacctgtta gtgctcctat tgcttcaata gtaccaattt
    19441 tcactattcc ttttattgca agatagcctg ttaaaaaaac gagagatatc tgaaaaaaaa
    19501 tattgagaaa gaagctaata gcgcctgcta acgtttctac agttgtcttt ctttgtataa
    19561 ccatctttaa taaaattcct gcttctttaa ttttcttagg caatacatat aaaagattca
    19621 aggatgctaa cacatcaaat ccattcaata tagtctcact agattttaaa aaagcttcat
    19681 tttggttagt taaatttaga ctaacttctc gcattttcga tgcaaagatt tttggtacaa
    19741 gtagcataat cattaatgaa aacaaggtgg ctacagtcaa tgaccaatga tagtgattaa
    19801 gagtcacaac tgcaaatata gtaccagaaa ttccttttat tactaaaaaa agttgtttaa
    19861 aagcctgatc atttaaagtc tgaacatcat tatttagcca cgaaagatat gttcctgatg
    19921 atttactatg aaattcttga taggtagagt tagagatgtc tgtggcaact ctatttcgaa
    19981 tctctagatt aaactcttgg atcacttcaa cctgataatt tttcactacc cagtcaagga
    20041 atattatccc acaccagaca atcatttggt agattgacaa tttcaaaaac cgctctaaat
    20101 tcatcgcaat taattcattc aacaccagag cattaatagt tgctgcataa attagcaata
    20161 attgaccagc aacaataaat atcgttaata aactaaattt ttttatattt gattttataa
    20221 tagtatacac aatagtttct cactttctaa attttaattg aacatagttg tcatatatac
    20281 aatagaaaaa accaaaatga tataataaca tatatttcaa aaaaagaaat tcgttaaaaa
    20341 ttttttcttc tcttgccttc ttgattactt ttaaagcctt gcatttgtct cctattaata
    20401 gtaaccgctt tatgtttaaa gaataatatt tctttgtaac caatattctc tcgttgaaac
    20461 tcaataaatt aaaatatttc ctacagtaat tataatattc ttcatctgca ttaattgttt
    20521 tttgtgtcac tccagtgata ccgttttctt tactgtgagc gtagtaattc accaagaatt
    20581 ctcgcactat atcaatttgg tatccttgag caagtagttt taataaaaca acaccgtcct
    20641 gatgtgaatc tattttctca aaaccattaa ttaattctag cacctctttt ttacacaacc
    20701 aaaatgacgt acctgctata ttgtgaacca tttgaacaaa caagggattt ccaacaaaat
    20761 cggtcttctc ctcttctcgt gtaccatttg gataaattat tattccataa ctataaacta
    20821 aagctaaatt cttcattcta ctctttttaa aacaagccat caactttaaa attcgatctg
    20881 acatatattc atcatcatcg tctaaaaatg atatatactt acctctagaa tttttgatac
    20941 ctatgtttct ggcattagtt gcacctaaat cttcattact taaaattaac ttaattctat
    21001 gattggtata gccaaattga tggataattt tatttcttaa atttacatta ctataattat
    21061 catcaataat tataacttcg atatttttat aactttgatg taaacaactt ttcacagctc
    21121 taatcagaga ttcataccta ttatgtgttg gtattataat acttactaat tcttgatcta
    21181 tattcctatc catgactact cttctctaat aattcatcat atactctcat ggtttctaca
    21241 aacatttttt gcacagaaaa atgttttctt atttttgatt tactattctc acctatatat
    21301 ttcaaatact cagaatcatt gagtaaaaaa ttagcacaag cacacactcc ctcaacatct
    21361 tccttctcaa ataaaaatcc atcaacccta tgttcaataa tttcacttaa cccgccaaca
    21421 ttactagcta aaaccggagt tccttgtgac attgactcta aaacacacat aggtattcct
    21481 tctgtatcag aaggaatata caataaatcc gatatttggt aaactatagt agctggatag
    21541 atttcaccaa gtaacctgaa attatctcta catttcaaat ggcaaatttt ttctttcaaa
    21601 gcagcccaca tactaccatt tccagccata ataaaaatca catcttctct gactaaaaat
    21661 aatttttctg caaattcaag gaatctatcc ggcctttttt ctggatccaa ccttccaaca
    21721 taacaaatga tttttttgtt atttggaata caaaattctt ttttaaagtc ttgaacacct
    21781 actacatcta aatcgctatt tgatacatta attccgttat ttattgcaac tatcttctta
    21841 tttttttatt atactctcca atcttttttt catagtttca gatacacaaa taaaagcatc
    21901 tcccatagaa tatgtccaaa aatcaaaata agtcaagaat ttctttttta agttatattc
    21961 aacccatcca tggcatgtta tcactgtctt aacctttcca aatccattct tgtcaagttt
    22021 ttttaacata tataaaaaat aattagttga gtagccatga cagtgtataa gttggatttt
    22081 taataatttt aaaatatttt taacgtgtaa ggcagtttca aaattatttg aacattgagt
    22141 acaatcaaca taggcaatat ctaaattttt ataatcatca ataacctttg aatctctaga
    22201 tacgattatc aaaataggat atagagacat ccttctgatc tgctttttac aaagtccaat
    22261 tatatgcgga tctatacctc cacaatgtcc attattatac ctaactataa tatgagccga
    22321 aaacactata tccttaatgt ctccatatcc atcagggata ttaatattta tttttccaca
    22381 actatattgc attgtaacca tctccttaaa cgacgcatta tgatatttga tagagaaatt
    22441 tttatgaata actcaataat tttatagtaa atcatgctta tatctcaaag atacctattt
    22501 tctcttgtct cgaccttctc caaagaattg ctataatact attacaaata catctgcact
    22561 acacttcaaa ttttagcact gtataaaaac gtttcaacac actaacttta agaaaacttc
    22621 cactattaat tgaaaaagtt gatagagata aattaaagat ctatattgaa actcatcccg
    22681 atgcttattt gactgaaata gctgctgaat tcaactgtcc tccaacaact attcattacg
    22741 ctctaaaggc tatgggatat agtctaaaaa agagctgtac ctactgcgaa caagacccag
    22801 aaaaagtaaa tcggttcctt aaagaattga atcacttaag ctacctgact cctatttata
    22861 tttatgagac aggggttgag acctattttt atctcgaata tgatcgagcc ttgagcaggc
    22921 agttagtctc tctggaagaa gatataatta tttgaattaa gatcgagaca acgcacacca
    22981 gagattgcga tactgttata gaagtactaa tgcccttttt tgtttcaata tactatggct
    23041 ccgatgacct ataaagatac gatgacgagt gactttttcg aagcttgctt ccaaaaattc
    23101 ttactaccta ctttagatac accatccctt atcattatgg acaatgcaag gtttcacaga
    23161 atgaacatgt gtaaggagca gggcatagac tgttaccact tcctacctat tcacccgagt
    23221 ataatcccat tgagaaaata tgggcttaca tcaaaaacat ctcagaataa tattgtcaaa
    23281 ttacgatgct tttcttgagg cacttttgtc ctattcttgt ttcagccgac tatactccgt
    23341 tattgggcag ctacggaaca gtcgatggga cgatgggggg acataaaaaa atcctccagt
    23401 tttgtttttt ataacagtat actggagaat tgacaatctc ggtagatacc tcgttatagc
    23461 gcggttactt attaggcagt tacaaaacaa ctgtgaacag aaaacattcc agagtcagac
    23521 aagactttgg aatgttttgg ctctataatt tctgtagtgg gtaatcccac cccaggaatt
    23581 atagggtcgt ttcttgtaga aaaaaagccc catatgacct ataatgaaaa gcgtctaacc
    23641 aactcattag aaagggttca tatggaacaa cttaagaata ccacagattt gctcggattg
    23701 aaagacaaaa atatcaaaat cttgtctgtt ctgaaatacc aaacccatct agtcgttcag
    23761 gcaaagttgg attcccccgc tcctccttgt cctcattgtc aagggaagat gatcaaatac
    23821 gacttccaga aagcctctaa aattccgctt ctcgactgtc agggtttacc cacggtacta
    23881 catctcaaaa agcgccgctt tcagtgcaag aattgcctta aggtggtcgt ttctcaaaca
    23941 tccattgtca agaaaaattg ccagatttcc aacatggtga gacaaaaaat cgctcagctc
    24001 ctccttgaaa agcagtctat gactgagatt gcccacagat tggcggtctc aacttccacc
    24061 gtcatccgaa aactgaggga atttaagttt gaaaccgatt ggaccaagtt gccaaaagtt
    24121 atgagttggg atgagtatag cttcaaaaag agcaaaatga gcttcattgc ccaagat
//
