LOCUS       NZ_FEEQ01000001        22176 bp    DNA     linear   CON 04-JAN-2025
DEFINITION  Streptococcus pneumoniae strain 2842STDY5644069, whole genome
            shotgun sequence.
ACCESSION   NZ_FEEQ01000001
VERSION     NZ_FEEQ01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900047005.1-RS_2025_01_04
            Annotation Date                   :: 01/04/2025 01:43:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,253
            CDSs (total)                      :: 2,202
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 86 of 184
            Pseudo Genes (incomplete)         :: 88 of 184
            Pseudo Genes (internal stop)      :: 60 of 184
            Pseudo Genes (multiple problems)  :: 40 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:55:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 22176
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FEEQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22176
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     gene            <1..557
                     /locus_tag="A1T31_RS00010"
                     /old_locus_tag="ERS367508_00001"
                     /pseudo=""
     cand_cluster    1..22176
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1003:2176](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1004..2176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     CDS             <5..557
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="A1T31_RS00010"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00001"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RRSQWVEVTLVQSGFTISRTPLSSEDTVMIDATEVQINRPKKRIS
                     ESFW"
     gene            625..873
                     /locus_tag="A1T31_RS00015"
                     /old_locus_tag="ERS367508_00002"
     CDS             625..873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /locus_tag="A1T31_RS00015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00002"
                     /product="hypothetical protein"
                     /protein_id="WP_001814299.1"
                     /transl_table=11
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFYQ
                     KFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            1004..2176
                     /locus_tag="A1T31_RS00020"
                     /old_locus_tag="ERS367508_00003"
     CDS             1004..2176
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /locus_tag="A1T31_RS00020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00003"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_000151960.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 7.1e-09,
                     bitscore: 29.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSIA
                     PLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFARS
                     FEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAMLIT
                     QNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQKRYQL
                     TLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGNIYTGS
                     LFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLNKLNQRT
                     ALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            2176..3450
                     /locus_tag="A1T31_RS00025"
                     /old_locus_tag="ERS367508_00004"
     CDS             2176..3450
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /locus_tag="A1T31_RS00025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00004"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_000704388.1"
                     /transl_table=11
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVA
                     DQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQ
                     VHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIK
                     GEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTAS
                     CRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWR
                     AIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHD
                     LLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAP
                     LVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3485..4450)
                     /locus_tag="A1T31_RS00030"
                     /old_locus_tag="ERS367508_00005"
     CDS             complement(3485..4450)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /locus_tag="A1T31_RS00030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00005"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_000225980.1"
                     /transl_table=11
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4431..5885)
                     /locus_tag="A1T31_RS00035"
                     /old_locus_tag="ERS367508_00006"
     CDS             complement(4431..5885)
                     /EC_number="3.2.1.26"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /locus_tag="A1T31_RS00035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00006"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_000455313.1"
                     /transl_table=11
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNGILIKSGNPTGTYYELDYGRKTN"
     misc_feature    complement(5962..5977)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.4"
                     /tool="antismash"
     misc_feature    6075..6089
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.76"
                     /tool="antismash"
     gene            6262..8145
                     /locus_tag="A1T31_RS00045"
                     /old_locus_tag="ERS367508_00007"
     CDS             6262..8145
                     /EC_number="2.7.1.211"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /locus_tag="A1T31_RS00045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00007"
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="WP_001064552.1"
                     /transl_table=11
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGV
                     VYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKVAQGDKVKVGD
                     VLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI"
     gene            8294..9181
                     /gene="scrK"
                     /locus_tag="A1T31_RS00050"
                     /old_locus_tag="ERS367508_00008"
     CDS             8294..9181
                     /EC_number="2.7.1.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008865 - fructokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scrK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /locus_tag="A1T31_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00008"
                     /product="fructokinase ScrK"
                     /protein_id="WP_000164313.1"
                     /transl_table=11
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(9501..10118)
                     /locus_tag="A1T31_RS00055"
                     /old_locus_tag="ERS367508_00009"
     CDS             complement(9501..10118)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /locus_tag="A1T31_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00009"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_000076185.1"
                     /transl_table=11
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSK
                     ETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGIVI
                     GCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADFLCM
                     LAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10533..>10721)
                     /locus_tag="A1T31_RS00060"
                     /pseudo=""
     CDS             complement(10533..>10721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /locus_tag="A1T31_RS00060"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSNENHNRLIHR"
     misc_feature    complement(10716..10732)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     gene            complement(11114..11305)
                     /locus_tag="A1T31_RS13115"
     CDS             complement(11114..11305)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1T31_RS13115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_000693430.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVSN
                     YTYGKAKLTWFEEIFEEY"
     gene            11428..12321
                     /locus_tag="A1T31_RS00070"
                     /old_locus_tag="ERS367508_00010"
     CDS             11428..12321
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /locus_tag="A1T31_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00010"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000895292.1"
                     /transl_table=11
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIFH
                     SILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDAKE
                     VKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLDPVN
                     TELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQYGKT
                     RLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIATFDQQ
                     APTIDEIFKLESGVEV"
     gene            12318..13517
                     /locus_tag="A1T31_RS00075"
                     /old_locus_tag="ERS367508_00011"
     CDS             12318..13517
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /locus_tag="A1T31_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00011"
                     /product="ABC transporter permease"
                     /protein_id="WP_001245377.1"
                     /transl_table=11
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGSS
                     MAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLK
                     AVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEAKEN
                     KKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMA
                     LFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISLFMYVV
                     LAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPFISTFFM
                     PFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
                     "
     gene            complement(13870..14637)
                     /locus_tag="A1T31_RS00080"
                     /old_locus_tag="ERS367508_00012"
     CDS             complement(13870..14637)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /locus_tag="A1T31_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00012"
                     /product="membrane protein"
                     /protein_id="WP_000498745.1"
                     /transl_table=11
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQE
                     SQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITAKL
                     IGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLNTIS
                     GILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGLNDHF
                     YMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     misc_feature    complement(14596..14611)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(14654..15349)
                     /locus_tag="A1T31_RS00085"
                     /old_locus_tag="ERS367508_00013"
     CDS             complement(14654..15349)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /locus_tag="A1T31_RS00085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00013"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000054195.1"
                     /transl_table=11
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTTL
                     IKLINGLLQPDQGRVLINDIDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYKDF
                     NLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPAARA
                     YILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESGESID
                     QLFRQEFKA"
     gene            complement(15354..15719)
                     /locus_tag="A1T31_RS00090"
                     /old_locus_tag="ERS367508_00014"
     CDS             complement(15354..15719)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /locus_tag="A1T31_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00014"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000119153.1"
                     /transl_table=11
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEAG
                     VNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTHFG
                     YEKEELPGVVSDYIKGV"
     gene            15859..16332
                     /gene="nrdR"
                     /locus_tag="A1T31_RS00095"
                     /old_locus_tag="ERS367508_00015"
     CDS             15859..16332
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /locus_tag="A1T31_RS00095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00015"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_001203672.1"
                     /transl_table=11
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVE
                     ERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQ
                     SEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            16333..17502
                     /locus_tag="A1T31_RS00100"
                     /old_locus_tag="ERS367508_00016"
     CDS             16333..17502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /locus_tag="A1T31_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00016"
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="WP_000802390.1"
                     /transl_table=11
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISFW
                     DNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQDFL
                     EHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKKVAN
                     DFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVISTKR
                     MREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTTTQTERELLQQMAGL
                     GLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRERGQKAKT
                     QKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17503..18399
                     /gene="dnaI"
                     /locus_tag="A1T31_RS00105"
                     /old_locus_tag="ERS367508_00017"
     CDS             17503..18399
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /locus_tag="A1T31_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00017"
                     /product="primosomal protein DnaI"
                     /protein_id="WP_000446531.1"
                     /transl_table=11
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEELN
                     RSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAAIK
                     NRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGVGKS
                     FMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILDDIGA
                     EQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEARRVME
                     RIRYLAEETRLEGVNRR"
     gene            18396..19109
                     /locus_tag="A1T31_RS00110"
                     /old_locus_tag="ERS367508_00018"
     CDS             18396..19109
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /locus_tag="A1T31_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00018"
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="WP_000140849.1"
                     /sec_met_domain="PF00881 (E-value: 1.4e-22, bitscore: 74.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQS
                     YSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGL
                     LISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMALGVP
                     NQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQA
                     EPSSTRKNLEQKKLL"
     gene            19123..20433
                     /gene="der"
                     /locus_tag="A1T31_RS00115"
                     /old_locus_tag="ERS367508_00019"
     CDS             19123..20433
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /locus_tag="A1T31_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00019"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_001207696.1"
                     /transl_table=11
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYAT
                     GEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVA
                     RKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENL
                     PNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDG
                     QEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGF
                     AHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLP
                     EMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFV
                     NEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     misc_feature    20488..20499
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.14"
                     /tool="antismash"
     gene            20524..20859
                     /locus_tag="A1T31_RS00120"
                     /old_locus_tag="ERS367508_00020"
     CDS             20524..20859
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /locus_tag="A1T31_RS00120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00020"
                     /product="hypothetical protein"
                     /protein_id="WP_000400493.1"
                     /transl_table=11
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFYS
                     LFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQELG
                     KSKGGRH"
     gene            21000..21335
                     /locus_tag="A1T31_RS00125"
                     /old_locus_tag="ERS367508_00021"
     CDS             21000..21335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /locus_tag="A1T31_RS00125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS367508_00021"
                     /product="hypothetical protein"
                     /protein_id="WP_000400503.1"
                     /transl_table=11
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLYA
                     LFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRELG
                     KSKGGRH"
     misc_feature    complement(21865..21877)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.78"
                     /tool="antismash"
ORIGIN
        1 tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggttttacg atttcaagaa
       61 ctcctctcag ttctgaggac acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc
      121 ctaaaaaaag aattagcgaa tcattctggt aaaaaaaatg ccacgctatg aaggctcaag
      181 cgattgtcac aagtcaaggg agaattgttt ctttggatat cgctgtgaac tattgtcatg
      241 atatgaagtt gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg
      301 acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca
      361 gcaaactcaa gccactaaca gttgaagata aagcctataa ccatgcgcta tccaaggaga
      421 gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct
      481 atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gattgctggc attatcaatc
      541 atgaactagg attctagttt tgcaggaagt ctactacttt ccttattgtc tgtaaatcta
      601 ctgaccttgt tgtttatccc agtcatggtt tctagttcgg gctcagagtt tcaaagtgga
      661 tggcaagagc atcaattgat tgctgagaag gttagtaaaa cacttgataa gacatttgat
      721 aaggatgtca gagaaattcc gatcagtcag ttttatcaaa aatttgtaga tgagatggga
      781 aggatttact caggaaattt gatcctccag gagctgataa ctgtgaatgg agcttataaa
      841 gctacttata tcggtgaact ctctagcaac taatcattct ttaaaatgat gaccaataag
      901 aggcttgatt tggtgaatca agtctttttt ctctctttta ctgccatttg tgataaaata
      961 gtatagaacg attttttaca tgaatgataa aacagaggta aatatgacaa tcggtattga
     1021 taagattggt tttgcgacca gtcaatatgt cttgaaatta caagacttag cagaagcgag
     1081 gggaattgac cctgaaaaat taagtaaagg actcttactc aaggaattga gtattgcgcc
     1141 cctaactgag gacatcgtga ccttggcggc cagtgctagt gactctattt taactgagca
     1201 agaaagacaa gaagttgaca tggtcattgt ggctaccgag tcaggaattg accagagtaa
     1261 ggctgcggcc gtctttgtgc atggcttgct gggcatccag ccctttgctc gtagtttcga
     1321 gattaaagaa gcctgctatg gggcgacagc tgccctccat tatgccaaat tgcatgtgga
     1381 aaattctccg gagtccaagg tcttggtcat tgccagtgat attgccaaat atggtattga
     1441 aactccggga gaaccaactc aaggtgctgg aagtgtagct atgttgatta cacaaaatcc
     1501 acgcatgatg gcctttaata atgacaatgt agctcagacc cgtgacatca tggatttctg
     1561 gcgaccaaat tactcgacaa ctccttatgt aaatggtgtc tattctaccc aacaatactt
     1621 ggatagtttg aaaacgactt ggcttgaata tcaaaaacgc taccagctta ctttggatga
     1681 ttttgcggct gtttgtttcc acttgcctta tcctaaatta gcgctaaaag gcttgaaaaa
     1741 aatcatggat aagagcctgc ctcaagagaa aaaagacctc ttacaaaagc attttgacca
     1801 gtctattctc tacagtcaaa aggtggggaa tatctacaca ggttcacttt tccttggact
     1861 tttgtctctc ttggaaaata cagatagctt gaaagctggg gataaaatcg ccctttatag
     1921 ttacggaagt ggagctgtgg ctgagttctt cagtggtgaa ttggttgaag gatatgaagc
     1981 ttatttggat aaagaccgct tgaacaagct caaccaacga actgccctat ccgttgcaga
     2041 ctatgaaaag gtcttttttg aggaagtaaa cttggatgaa acaaactctg cccagtttgc
     2101 tggctatgaa aatcaagatt ttgccttggt tgaaattctt gaccaccaac gccgttatag
     2161 caaggttgaa aaataatgaa gataagttgg aatggatttt ctaaaaaatc ataccaagag
     2221 cgcctcgagc tgctaaaagc tcaggcgctc cttagtcctg agagacaagc tagtctggag
     2281 aaggatgaac agatgagtgt gactgtggca gaccagctga gtgagaatgt ggtgggaact
     2341 ttttctctgc cttattcgct ggttccggag gtacttgtca acggtcagga atacaccgtt
     2401 ccctatgtga cagaagaacc ctctgtggtt gcggcggcca gctatgccag caaaatcatc
     2461 aagcgtgcag gtggttttac tgcacaagtc catcagcgcc agatgattgg gcaggtagcc
     2521 ctttatcaag ttgctaatcc taaactagcg caagagaaga ttgccagcaa gaaagcggag
     2581 ctcttggagc ttgccaatca agcctatcct tctatcgtta aacgtggggg tggggcgcgt
     2641 gatctgcatg tcgagcagat aaaaggcgaa ccagactttc tcgttgttta tattcatgtc
     2701 gatacccagg aagccatggg tgccaatatg ctcaacacca tgctggaagc cttgaaacca
     2761 gtcttagaag aactcagtca gggacagagt ctcatgggaa tcctgtccaa ctacgcgact
     2821 gattctctgg tgactgcaag ctgtcgcatc gcctttcgct acttgagccg ccaaaaggat
     2881 caaggacgag agattgcgga gaaaattgcg ttggctagtc agtttgcgca ggctgatcct
     2941 taccgagctg ctactcataa taaaggaatt tttaatggta ttgatgcgat tttgattgcc
     3001 actggtaatg actggcgtgc catcgaagct ggggcccatg cctttgccag tcgagatgga
     3061 cgctatcaag gtcttagctg ctggacgctg gaccttgaaa gagaagaatt ggtcggtgag
     3121 atgaccctgc ccatgcctgt agcgactaag ggtggctcta tcggcctcaa cccacgtgta
     3181 gctctcagtc atgatctact aggaaatcct tctgccagag aattagccca gattatcgtg
     3241 tccatcggtc ttgctcaaaa ttttgcagcc ctcaaagcct tggtaagtac gggcatccag
     3301 caaggccaca tgaaactaca ggccaaatcc ctagctctcc tagctggggc tagtgaatct
     3361 gaagttgctc ccctagtaga gcgcctcatc tcagataaaa cctttaacct agagacagcc
     3421 cagcgctatc tcgaaaattt aagatcataa aaactcagac gaatcggtct gagttttctt
     3481 gtgtttaaat actttttcct ggtaatagcg taactggtaa gaagtaacca gttgtggcga
     3541 cttccttgcc ttcaatcttt tgcaagagaa gatcaatagt gagacaagca atctcttcca
     3601 aaggttgctt gatagtagcc aattgagggt agtaattttc gataaagtag gtcccatcat
     3661 agccgatgac cttgagctct tttgggacag aaatgcccaa ttcttgagcg attttaatga
     3721 ccagaatagc tgtcaaatca tccgaagcaa aaatggcatc tggtttttcc cgggtcaaga
     3781 tattcttgat ttccatttct tttctgacgg gagaaaagtc actggaaaca ttgataatag
     3841 gagcttttgg gagtacggat gcaaaaccag cgtggcgcag tccggttggc gaattggaat
     3901 tgtcattccc tgtaatcatg atgatagact gggcacctgt cttgaccaag gtttgggcag
     3961 caagaacccc accagcatag ttgtcagagg agacgacagg gatgtctggc gataggtttc
     4021 ggtcaaagga aataatcggc gctgtcacac gattgtagtc ttcgattcct aggttgtgac
     4081 taccagaaat gatgccgtcc acctgattgg cttccaacat ttcgatgtat tcacgttcct
     4141 tctcagaatc atgttcactg ttgcagatga tggtcttgta accatttttg aagagttggt
     4201 gttccaattt atcaatcaat tctgcataga aaacattgga aatattgggg aaaatcaagc
     4261 cgattaactt agctggtttt ccttgcagac tacgagccag gttgttgggt ttatagccca
     4321 attctcgcat ggcttcattg actttttgga tggttttctc agatagatat ccttttttat
     4381 tgataacccg agaaacggta gtaggactga cgcctgcaag tttggcgaca tcagttagtt
     4441 ttgcgaccat aatctaattc atagtaagtt ccagttgggt ttccagattt gatcaggata
     4501 ccattttggt ccgcatgtgg gaagacacga ccagaaaata ctttttctcc tttattgatg
     4561 aaaatttcaa agacagagtt atcgatgaag attgtagcag tagtagcctg attctcgata
     4621 gggcaagaac gagttatccc aaattcttgg gcatactgct ctccagcctg gctacgatcc
     4681 actgtcactt gaccgtttac aaggtcaaag ttgattgaaa gtcccttacc ttctttatca
     4741 gcaagtaaga caatctcgct ctggctatta gcttccaagt tgagttcaag ttcgtaagtg
     4801 ttcttggttt gggaacggtt tgagaaggct tcttcagaag tacgaaggtc cttaatagca
     4861 gcgactggat actggtagag cttgtcgtct ttgatagtga gttccttgac caaagagaag
     4921 gttccttggt ggtcaaaacg gtcagatggg taagaaacat ctggcaaacc aagccagcta
     4981 actgctagag cacgcccatc aggagcgttg aaggcttgag ttgcataggc ttcgaaaccg
     5041 taatccatgt tttgaagttg agacacatct accattttgg catttttagg gtcaaaggaa
     5101 gccccaatct tatacatatt tggaaagata ttatcgtagt ctagaacttt cttatccaat
     5161 ccttgtggac agtagagaag gacaggctgt tcctctacaa agaccagatt aggacattcc
     5221 atcatgtagg cagtacggtc gttagcaaag tcaaggtcgc caactgcttg ccagtttgtg
     5281 tagtcgttat tgacagcctt gtagagacgg acgaagcctt ttttctccaa gtcctgtcca
     5341 ccgacgacag catagtattg acctttaaag ttaaaaattt gtggatcgcg gaagtggtca
     5401 gtagagtctg ctggctggtc aatcaagatc ttgtcaatct ttgtaatctt accctccttg
     5461 tccatcaaag caccgatctg gtatgggtga cggatccagt tttcatcgcg aacatttcct
     5521 gtataaaata ggaataagtt atcgccaaat tgcatggcag aaccagagta ggcaccgtga
     5581 ctatctaatg gagtatctgg caaaactttg actccagttt ctctaaagtg aaccaaatca
     5641 tcactttcta gctgtgccca agattttaaa ccgtgggctg caccaaaagg aaaattctgg
     5701 taaaagagga tccacttgcc atcaaagtaa gaaaagccat ttgggtcgtt gagaagtcct
     5761 gtttttggct caacatggta atgagtatgc catggagatt gtgccatatt ttcctttata
     5821 tgttgaattt cttcttgcgt ccaatcttga taaagtctgt aacgacgctc agttgtccat
     5881 tccattcatt cctccaaaaa tcttatcact tttaatagta actgttttcg ataaaaaatg
     5941 caagcccttt atgttaaaaa agagaaaaaa ctgtcaaacg attatcataa aataaataca
     6001 ggaaatcaat caaattttta cgaaaatgtg aaagataatg aaataaaaga ctttttaacc
     6061 aaggtttcaa acttattttt caagaaattc ctgatgaaac agtcaaaaac aatcaatcta
     6121 aagcttgccc actaagtaga tagaatattt tttctgcaaa acgcttgaca tatttttaaa
     6181 acatgataaa ataatagtcg taagggcgaa taaaatcgct ttcaaacaag aacaaaatgt
     6241 tatataagga gatttttgca aatgaacaat caggaaattg caaaaaaagt catcgatgcc
     6301 ttgggcggac gtgaaaatgt caatagtgtt gcccactgtg cgacacgtct acgtgtcatg
     6361 gtcaaagatg aagagaaaat caataaagaa gtgattgaga acttggaaaa agttcaaggt
     6421 gctttcttta actcagggca ataccaaatt atctttggta caggtacagt taacaaaatg
     6481 tacgatgaag ttgttgtact tggattacca acatcatcta aggatgacat gaaagcagaa
     6541 gttgctaaac aagggaactg gttccaacgt gctatccgta cttttggtga tgttttcgtt
     6601 ccaatcatcc cagttatcgt agcgacaggt ctcttcatgg gtgtgcgtgg tcttttcaac
     6661 gctcttgaaa tgccacttcc aggtgacttt gcaacttaca cacaaatctt gacagataca
     6721 gccttcatca tcttgccagg tttggttgtg tggtcaacct tccgtgtatt tggtggaaat
     6781 cctgccgttg gtatcgttct tggtatgatg cttgtctctg gctcacttcc aaacgcttgg
     6841 gcagttgctc aaggtggtga agtaacagcg atgaacttct ttggtttcat ccctgttgtt
     6901 ggtttgcaag gttccgttct tccagccttc atcatcgggg ttgtcggagc taaatttgaa
     6961 aaagctgtcc gcaaggttgt tccagatgtc attgacctct tggtaacacc attcgtgaca
     7021 cttttggtca tgtctatcct tggactcttt gtcattggac cagttttcca cgttgttgaa
     7081 aactacatcc ttattgctac aaaagcgatt cttagcatgc catttggtct tggtggtttc
     7141 ttgattggtg gggttcacca attgatcgtc gtgtcaggtg tgcaccacat cttcaacttg
     7201 cttgaagtgc aattacttgc tgctgaccat gctaacccat tcaacgctat catcacagct
     7261 gctatgacag ctcaaggtgc tgctactgtt gcggttggtg ttaaaacaaa aaatccaaaa
     7321 ctgaaaacac ttgctttccc ggctgctctt tctgccttcc taggtattac agagcctgct
     7381 atcttcgggg tgaacttgcg cttccgtaaa ccattcttcc tttcattgat tgctggtgca
     7441 atcggtggtg gattggcttc tatccttgga cttgctggta ctggtaatgg tatcaccatc
     7501 atccctggta caatgcttta tgttggtaac ggacaacttc cacaatacct tcttatggta
     7561 gctgtatcat ttgcccttgg ttttgctctt acttacatgt ttggttacga agatgaagta
     7621 gacgcaactg cagctgcaaa acaagctgaa gtggctgaag aaaaagaaga agttgcgcca
     7681 gcagctcttc aaaatgaaac acttgtaact cctatcgtcg gtgatgttgt cgctcttgct
     7741 gatgtcaatg acccagtctt ctcaagtgga gctatgggac aaggtatcgc tgtgaaacca
     7801 agccaaggcg tggtctatgc accagctgat gctgaagttt caattgcctt tccaacaggg
     7861 cacgcttttg gtttgaaaac aagaaatggt gctgaagttt tgattcatgt tggtattgac
     7921 actgtatcta tgaacggtga cggttttgaa gcaaaagttg ctcaaggtga taaggtgaaa
     7981 gttggcgatg ttcttggaac atttgactca aataaaatcg ctacagctgg acttgatgat
     8041 acaacaatgg ttatcgttac aaatacagct gactacgctt cagtagctcc agtcgcaaca
     8101 ggttcagttg cgaaggggga tgctgtgatc gaagtgaaaa tctaatcaat cctctctaat
     8161 gtgaaaacga acaaatgaca tgtttgttcg tttttattag atagtaagat ttacagagga
     8221 aaatctaaaa aatagagaca tttagacttt cgaagtatgc tataataaag aaaataaaaa
     8281 caagaggttt atcatgacaa aattatatgg aagcttggaa gctggcggta caaagtttgt
     8341 ctgtgctgtc ggtgatgaaa actttaacgt tgtagaaaaa acacaatttc caacaacaac
     8401 tccaatcgaa acaatcgata aaaccattga gttcttctca aaattcgata accttgctgg
     8461 tcttgcagtt ggttcatttg ggccgattga tattgacaaa aactcaaaaa cttatggctt
     8521 tatcacgacg actccaaaac caaactgggc aaatgtggac ttgcttggtg cccttcgtcg
     8581 cgccctaaac gtgccaatgt acttcacaac agacgtaaac agctctgctt acggtgaagt
     8641 ggttgcccgt aacaatgctg gtggtcgtat cgaaaacttg gtttactaca caatcggtac
     8701 aggtatcggt gcaggcgtca tccaacgtgg tgagtttatc ggtggtgtgg gtcaccctga
     8761 aatgggtcat tattatgttg ctagacaccc aatggatatt gaaaaagagt ttaagggtgt
     8821 ttgtcctttc cataagggat gtctggaagg ctatgcagct ggtccaagtt tggaagctcg
     8881 tacaggtgta cgtggggaaa ctattgaact caacaaccct gtttgggatg ttcaagccta
     8941 ctatatcgct caagctgcgg ttaatgcgac agtgactttc cgcccagacg tgattgtctt
     9001 tggtggaggg gtcatggctc aacaacatat gctggaccgt gtccgtgaga aatttacatc
     9061 tcttcttaat ggttacctac cagtaccaga tgtgcgtgac tatatcgtga cgccagcagt
     9121 cgcaggaaat ggttctgcca cacttgggaa ctttgttctt gcaaaagaag tttcaaaata
     9181 aagcacaaaa tccgcttggg aaaccaaacg gattttgtgg ttgaaaacaa tatttttgag
     9241 cctttcctta agtgattacg gacggtagcg actttcttcg aaattccata cctaaacttt
     9301 gagacactag gctcaaagtt tccgaacacc tgaaaccatt agatttcagg tgtttctatc
     9361 acggtggaaa ggctaggtaa gtcctcgctt cactatcgaa aaatatgcat gatttccata
     9421 ccaaagtata tttagtatca agctatagtt aatctacgct ttaaaaatcc acttgggaaa
     9481 ccaaacggat tttttacgtg tcaaagcatt tgccagaaaa agtcaataat ataggtcaga
     9541 ccgtaggtat aaaccacgag ggtaaagggt ttggtcagaa tgatgatggt catgtagcgc
     9601 ttgaaactca tcttggtcag ggcagccagc atacagagaa agtcagctgg gctaatgggc
     9661 caaatcatca taaaaataaa gaagcggtca aaacgattgc ccttatctag ccagccgatg
     9721 tacttgtcgt aggtgcgctt gctgacgaca gactggacaa aggcagctcc gtataggcgc
     9781 actagataaa agataatggc acagccaatc acgatgccga tatagttgta gatagtcccg
     9841 atgatgtgcc cgtagataaa gaccccagcc accgaggtca aggcccctgg aatgataggg
     9901 acgacagtct gtaaaatctg taaaaagata aagagaggtg gaccccagat gcctgcctgc
     9961 tggataaagg cagagagggt ttccttggat tgtaaaatcc cagcctgata agcccaaata
    10021 cagaaaatca aactcccaac cccaccgaca atcgatgaga tattgataac tcgctgcaaa
    10081 aggggagaaa cagctttcat ttgtttatcc tgtgacatgt aaactcctca tagatagtat
    10141 atttctacta taccatattt tggaggagaa agggggaatg agtctttttt gataaggaat
    10201 agaaagtaaa tagcccttcg agacttagaa taggtctgtc aactaaaggt tatatgcatt
    10261 ctaggtttcg aataatcgca attccataaa tttaaaagca ttctaagttt cgaatagctt
    10321 atctgagata attttgaggc attcgcgctt tcgaatagtc attttcccta aagtttagat
    10381 gtattctgaa gctagaaaga ctaaaatcta aaagtagtaa gagtctctct ctgatggacg
    10441 taatttatgg ctagtatgaa tcctttgaat tgttagttaa ttttaatatt aatcagttct
    10501 gaaataatta ctaaatatag ttagatggtg aattaattat tgctaaattt caagttcaag
    10561 ttagtcatcc agaagtcttc tctgggggac ttgtagttca agcatttttt aggatagttg
    10621 ttaatccact tttcgatgaa tgcgacttcc tttgtagtcg ttttcttagt ttcctgaggt
    10681 aactatctat gaatgagcct gttgtgattt tcattagatc ctataggggt gtgcataata
    10741 gatatagcag attgaaacta gaatagtata catctacttc taaaacattg ttagaaatca
    10801 atttgactgt cctgatcaat ttgtcctgtt cttatttcat tttactatat aatccttaga
    10861 aaacatatcg gacaagcggt tgaattctgt tccgtccatt agtagataaa ggattactcc
    10921 ttcttgaaat gacagatgaa cttgtttctt ataaaaatgt tgtctgaaac tattagcctt
    10981 tttccagaag ttttagagga agaaaacttt acgaggaaaa aggagttact caaataacaa
    11041 ttcaggatta aaaatagaca gttgaggagc ggaaggtata aattaagttt gctgctgtat
    11101 aatggattta tcactaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcgccttgc
    11161 cgtacgtata gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
    11221 tgacttcgtc agttttatct gcaacctcaa agctgtactt tgagcagtct acggctagct
    11281 tcctagtttg ctctttgatt ttcattgagt ataaaagtgc tccaggccat attttacaca
    11341 gcaatagtct tctaaaaatg gacaaaaaac attgtaaagg ctatcaaaaa ggagtataat
    11401 gagtgcaaga aatttcggag gtgaaagatg ctagaagtaa gaagtctaga gaaaagtttt
    11461 ggatccaagc aagttttgtt tggtattgac tttcaagcgc gaccaggtcg tattttggga
    11521 ctagtcggaa aaaatggtgc tggaaaaaca acgattttcc atagtatttt gaaattccta
    11581 gaatatcagg gagaaatcgg tctggatggt caggatattc gtcaggagac ctatgctcgg
    11641 attggttatc tgcctgaaga acgcagtctc atgcctaaat tgacagttct tgaacaagtt
    11701 cgctacttgg cgactctaaa aggcatggat gccaaagaag tcaaagaaaa actccctcaa
    11761 tggatgaaga ggttggaagt gaaaggaaag ctgacagata aaatcaagag tctgtcaaaa
    11821 ggaaatcagc agaagattca gctcattatt actctgattc atgaaccaga cctgattatc
    11881 ttggatgagc cttttagtgg attggaccca gttaatacag aattgctcaa acaagtcatt
    11941 tttcaggaaa aagagcgcgg agcaaccatt atcttttctg accatgtcat gaccaatgtt
    12001 gaggaacttt gtgacgatat tctgatgatc cgagatggcc gtgtggtctt gcacggacca
    12061 gttcaggatg tccgcaatca atacgggaaa acgcgtctct ttgtttcaag tgaacgaagc
    12121 aaggaagaat tggaaaatct tcctcatgtc aaacaggtga gcttgaccaa acaaggcagt
    12181 tggaaattga ttttggagga tgagagcgct ggaagggaac tcttcccaat cttgactcaa
    12241 ggtcaatata tcgcaacatt tgaccaacaa gcgccaacta tcgatgaaat ctttaaacta
    12301 gaatcaggag tggaagtatg agaaatatgt gggttgtaat caaggaaacc tatcttcgac
    12361 atgtcaagtc atggagtttc ttctttatgg tgatttcgcc gttcctcttt ttaggaatct
    12421 ctgtaggaat tgggcatatc caaggttctt ctatggctaa aaataataaa gtggcagtag
    12481 tgacaacagt gccatctgta gcagaaggac tgaagaatgt aaatggtgtt aacttcgact
    12541 ataaagacga agcaagtgcc aaagaagcaa ttaaagaaga aaaattaaaa ggttatttga
    12601 ccattgatca agaagatagt gttctaaagg cagtttatca tggcgaaaca tcgcttgaaa
    12661 atggaattaa atttgaggtt acaggtacac tcaatgaact gcaaaatcag cttaatcgtt
    12721 caactgcttc cttgtctcaa gagcaggaaa aacgcttagc gcagacaatt caattcacag
    12781 aaaagattga tgaagccaag gaaaataaaa agtttattca aacaattgca gcaggtgcct
    12841 taggattctt tctttatatg attctgatta cctatgcggg tgtaacagct caggaagttg
    12901 ccagtgaaaa aggcaccaaa attatggaag tcgttttttc tagcataagg gcaagtcact
    12961 atttctatgc gcggatgatg gctctgtttc tagtgatttt aacgcatatt gggatctatg
    13021 ttgtaggtgg tctggctgcc gttttgctct ttaaagattt gccattcttg gctcagtctg
    13081 gtattttgga tcacttggga gatgctatct cactgaatac cttgctcttt attttgatca
    13141 gtcttttcat gtatgtagtc ttggcagcct tcctaggatc tatggtttct cgtcctgagg
    13201 actcagggaa agccttgtcg cctttgatga ttttgattat gggtggtttt tttggagtga
    13261 cagctctagg tgcagctggt gacaatctcc tcttgaagat tggttcttat attcccttta
    13321 tttcgacctt ctttatgccg tttcgaacga ttaatggcta tgcgggggga gcagaagcat
    13381 ggatttcact tgctattaca gtgatttttg cggtggtagc aacaggattt atcggacgca
    13441 tgtatgctag tctcgttctt caaacggatg atttagggat ttggaaaacc tttaaacgtg
    13501 ccttatctta taaatagaag agccttgcga aagcgaggtt tttaaaggtg aaaagggtgg
    13561 aatcacgaac ctaattatgt acacattatg taaacaggtt gcttgaaaac tcaattgtat
    13621 agtgaactga atctggaata ggataatatt acttctaaaa cattcttata aattgatttg
    13681 aattccaaaa tcccatcgtt ccgttcttat ttcattttgc gatatagtga aaggaaataa
    13741 gtcagctcac aaaaaacgca taatatcaag gatttttaac acttgatact atgcgttttc
    13801 taattttaaa aactttttgc ctggtctctt ttgttctatg agtatgttac atatctaggt
    13861 aaaaattatt taaagcaaat taaccttatt tctcaagatg tagtaggttc cgagataaaa
    13921 gatagctatg aatatgagtt ctttaacaat ggctatacct gctcccatat agaaatggtc
    13981 attgagtcct accagtgaat tgacatagaa attagaacta agattgaaga aaagttcaat
    14041 aaatccaatg acgatttgga taccaatgta ggctgcaaca gcgagtgctg tacggtattc
    14101 attgaaaagc tgtccaatgg aaatagccag gtagatgcag aggattcctg aaatggtatt
    14161 tagtaggaag gatatacctg taagaaagat ctgagggaga tgtgtttcta caaatgtaat
    14221 cacataagaa agaggaatcc attctggagc tgttaaagcc agaataataa cagcacttag
    14281 agccaataca gcggtgctaa tcaatgacca gataaaggca ccgattagtt tggctgtgat
    14341 gatatggtgt tcagaaactg gcaaggtcaa agtcagatag ccttgtcggt cgtagacact
    14401 acctttgaag cgtttaataa tcaagaaaat ggttgaaatc gcaagtgtaa gcatcaagcc
    14461 accaaagact gtagctagaa aaagtagcat agtagcctga ctttcttggt aaggtagatt
    14521 tttaaagcct tgtgtctgta ttccgatgag ggcagaaagg actagcacgg ctgcgtagag
    14581 ggctaaatac cacttgttaa catttttaaa ttcgtagtga actaaattcc aaaacataaa
    14641 taatctcctt tgcttaggcc ttaaattcct gacggaagag ttggtcaatg gattcacctg
    14701 actcgtagcg aatatcatct acatttcctt gacggacgac ttttccgtct tttaggaaga
    14761 caatttcatc caagattggc tcgatatcag aaatcaagtg ggtagaaatc aaaacggtag
    14821 aagttggtga gtagttgttg ataatggtat tgaggatata agcacgggct gctggatcca
    14881 ccccaccaat gggttcatcc aaaacataga gacgagcatc acggctcata accaaaatca
    14941 gttgaacctt ttctttgttt ccttttgata gtttcttgag acgactattt tcatcaatgc
    15001 ccaggtctgc aagtagatga tgagcgcgtt caagattgaa atctttatag aaggtcttga
    15061 agtaggtaag ggcttctttg accttcattt gctcattgag ataggtcgta tcaggcaaat
    15121 aagctacaac ggccttggtt gctgggcttg ggtctatgtc gttgatgagg acacgtcctt
    15181 gatctggttg taagaggcca ttaattagtt taatcagggt tgtttttcct gagccgtttg
    15241 gcccaagaag gccgacaatt tttccagctg gaatgtcaag agaaacattt tcaagggctg
    15301 gtgttgctcc atatgatttg gatacatttt caaatgctag taatgacata ggcttaaact
    15361 cctttaatat aatcactgac tacgcctggt agttcttctt tttcatagcc aaaatgggtc
    15421 atggaggaaa cgaagtgttc caattcttct tctgataatt gtttgcgtga ctgagcgatt
    15481 agctccttat ccttagtcac aaatcgtcca gttgttcgct tgctgtagac aaatccttct
    15541 cgttcaaggt ctgataaggc tctttggatg gtattgggat tgacaccagc ctcgctagct
    15601 agctccctca cggttggaag ttgttgattg ggttccagtg tatgggaaac aatctgaagc
    15661 ttgattttct ccataatctg taaatagatg ggttttttgt tgtcaaatgt ccaggacatc
    15721 ttagtctcct ttctcttatc cttttgtctt aattaaataa tgcaacaaaa caaaaaactt
    15781 gtcaagcaaa aagaagaatt gttttgggaa tcgcttaaaa aatggtataa tgaaaagaaa
    15841 acgataagga gggaaaggat gcgttgtcca aaatgtgggg ctaccaagtc aagtgttatc
    15901 gatagtcgcc aagcagaaga agggaacacc attcgtagaa gacgtgagtg cgacgaatgc
    15961 caacaccgtt ttacaaccta cgaacgagta gaagaaagaa ccttagtggt tgttaaaaaa
    16021 gatggcacac gggaacaatt ctccagagat aaaatcttta atgggattat ccgctcagcc
    16081 cagaaacgtc ctgtgtcaag tgatgaaatc aacatggtag tcaatcgtat cgaacagaaa
    16141 ctccgtggtc gaaatgaaaa tgaaattcaa agtgaggaca ttggttcact cgtcatggag
    16201 gagttggctg aattggacga gattacctat gtacgttttg ctagtgtcta tcgtagtttt
    16261 aaggatgtca gtgagttaga gagcttgctc caacaaatca cccagtcctc taaaaagaaa
    16321 aaggaaagat aaatgaagcc aattgaccgt ttttcttatc taaagaataa tcgggtgtcg
    16381 caagatacct catctctggt acagtgctac ctcccgatta tcggtcagga ggcactgagc
    16441 ctttatcttt atacaatcag tttttgggat aatggtagaa aggaatatct tttttcaagt
    16501 atcctcaatc atctcaactt tgggatggat agactgataa aatcattgaa aatcttatct
    16561 gcttttaatc tcttgaccct ctatcaaaag ggggatgttt atcagctagc cctccatgct
    16621 cctctatcta gtcaagactt cttggagcat cctgtttatc gcagactctt agagaaaaag
    16681 attggcgact ctgctgtgga ggatttgaaa gttgaaagtg ctgatggtga agaaatacct
    16741 gtctcactca atcaagtctt tccagaattg gcagaactag gcagtcaaga agaccttggt
    16801 ctcaagaaga aagtggccaa tgattttgac ttggaacatt ttcgccagct gatggctcga
    16861 gatggacttc gttttgcgga tgagcagtcc gatgtcttaa acctctttgc tattgccgag
    16921 gagaagaaat ggacttggtt tgaaacctat caattggcca agtcaacagc tgtttctcag
    16981 gttatttcaa ccaaacgcat gcgtgaaaaa attgctcaaa aaccagtttc ctctgacttt
    17041 agtcttaagg aaacaaccat tatcaaagaa gccaaaagta aaactgccct gcagttcttg
    17101 gcagaaatca agcaaacacg caagggaacc actacccaaa cagaaagaga actcttgcaa
    17161 cagatggctg gcttgggctt gctggacgaa gtcatcaata tcattctttt attgaccttt
    17221 aataaggtcg attcggcaaa tatcaatgag aaatatgcca tgaaggtagc caatgactat
    17281 gcctatcaaa agattcattc ggcagaaaag gcagtcttgc gcatccgtga gcgaggacag
    17341 aaagcaaaaa cacaaaaaca gaatcagact gccccagtaa aaaccaatgt tcctaaatgg
    17401 agtaatcctg aatataagaa tgaaaccagc gaggaaactc gtctggaact agaacgtaag
    17461 aagcaagaac tattagctcg attagaaaaa ggaggagatt agatggaaag tgtcggagac
    17521 gtactcaaac gtcaacccag ccgtttttat tatcaagatt tggtccagaa aatcatgaag
    17581 gaccctgatg ttgcggcttt tatccagcaa gaatccttga ctccagagga attaaatcgc
    17641 agtatctcca agtttaatca gtacatcacc gagcgtgaca agtttctccg tggggatacg
    17701 gattatattg ccaaaggcta caagccgatt ttggttaaga atcatggcta tgcagatgtt
    17761 tcatatgaag aaactcctga gctaatcgcg gctgaaaaag aagcggctat taagaaccgt
    17821 ctcaagttaa tcaatctacc agccagtctc aagaaagcta gtttggctca agttgacttg
    17881 gatgatttgg ggcgcttacc agtttttgaa aagctactag ccttcgtgga gcaatatcca
    17941 gctattcgaa aaggtcttta cttatatgga gactttggtg tgggtaaaag tttcatggtg
    18001 gcggccttag ctcatgattt atcagaaaaa cgtggtgttt catcaactct cctccactat
    18061 cctagctttg tcattgatgt caaaaatgct atcagtgatg gcaatgttaa gaccttggtg
    18121 gatgagatta agctgtctga ggtcctgatt ttagatgata ttggcgccga gcaatcaacc
    18181 gtttgggtgc gtgacgaaat cctgcaggtc attctccaat atcggatgca ggaaaattta
    18241 ccgacctttt tcacatccaa cttcaacttt gaagatttgg agaagcattt tgcgaaagtg
    18301 aaacatggaa atgacgaaac ctgggaagcc agacgggtca tggaacgcat ccgttatttg
    18361 gctgaggaga ctcgtttaga aggagtaaac cgtcgatgac agaaaccatt aaattgatga
    18421 aggctcatac ttcagtgcgc aggtttaaag agcaagaaat tccccaagta gacttaaatg
    18481 agattttgac agcagcccag atggcatcat cttggaagaa tttccaatcc tactctgtga
    18541 ttgtggtacg aagtcaagag aagaaagatg ccttgtatga attggtacct caagaagcca
    18601 ttcgccagtc tgctgttttc cttctctttg tcggagattt gaaccgagca gaaaagggag
    18661 cccgacttca taccgacacc ttccaacccc aaggtgtgga aggtctcttg attagttcgg
    18721 tcgatgcagc tcttgctgga caaaacgcct tgttggcagc tgaaagcttg ggctatggtg
    18781 gtgtgattat cggtttggtt cgatacaagt ctgaagaagt ggcagagctc tttaacctac
    18841 ctgactacac ctattctgtc tttgggatgg cactgggtgt gccaaatcaa catcatgata
    18901 tgaaaccgag actgccacta gagaatgttg tctttgagga agaataccaa gaacagtcaa
    18961 ctgaggcaat ccaagcttat gaccgtgttc aggctgacta tgctggggcg cgtgcgacca
    19021 caagctggag tcagcgccta gcagaacagt ttggtcaagc tgaaccaagc tcaactagaa
    19081 aaaatcttga acagaagaaa ttattgtaga aagtgagaaa ttatggccct accaactatt
    19141 gccattgtag gacgtcccaa tgttgggaaa tcaaccctat ttaatcggat cgctggtgag
    19201 cgaatctcca ttgtagaaga tgtcgaagga gtgacacgtg accgtattta tgcaacgggt
    19261 gagtggctca atcgttcttt tagcatgatt gatacaggag gaattgatga tgtcgatgct
    19321 cctttcatgg aacaaatcaa gcaccaggca gaaattgcca tggaagaagc agatgttatc
    19381 gtttttgtcg tgtctggtaa ggaaggaatt actgatgcag acgaatacgt agctcgtaag
    19441 ctttataaga cccacaaacc agttatcctc gcagtcaaca aggtggacaa ccctgagatg
    19501 agaaatgata tatatgattt ctatgctctc ggtttgggtg aaccattgcc tatctcatct
    19561 gtccatggaa tcggtacagg ggatgtgcta gatgcgatcg tagaaaatct tccaaatgaa
    19621 tatgaggaag aaaatccaga tgtcattaag tttagcttga ttggtcgtcc taacgttgga
    19681 aaatcaagct tgatcaatgc tatcttggga gaagaccgtg ttattgctag tcctgttgct
    19741 ggaacaactc gtgatgccat tgatacccac tttacagata cagatggtca agagtttacc
    19801 atgattgata cggctggtat gcgtaagtct ggtaaggttt atgaaaatac tgagaaatac
    19861 tctgttatgc gtgccatgcg tgctattgac cgttcagatg tggtcttgat ggtcatcaat
    19921 gcggaagaag gcattcgtga gtacgacaag cgtatcgcag gatttgccca tgaagctggt
    19981 aaagggatga ttatcgtggt caacaagtgg gatacgcttg aaaaagataa ccacactatg
    20041 aaaaactggg aagaagatat ccgtgagcag ttccaatacc tgccttacgc accgattatc
    20101 tttgtatcag ctttaaccaa gcaacgtctc cacaaacttc ctgagatgat taagcaaatc
    20161 agcgaaagtc aaaatacacg tattccatca gctgtcttga acgatgtcat catggatgcc
    20221 attgccatca acccaacacc gacagacaaa ggaaaacgtc tcaagatttt ctatgcgacc
    20281 caagtggcaa ccaaaccacc aacctttgtc atctttgtca atgaagaaga actcatgcac
    20341 ttttcttacc tgcgtttctt ggaaaatcaa atccgcaagg cctttgtttt tgagggaaca
    20401 ccgattcatc tcatcgcaag aaaacgcaaa taaaaaagta gaatctggaa tgacagttcc
    20461 ggattttttt gatataataa aataatagaa aacgctatca aaagaaagag ggtgatgtcg
    20521 gtgatggaac atttgtttaa attcttactt ttagcaccgt acttttattt tgataactgg
    20581 attgagaagg ccaacagaaa tagtaagttt tttccaattt tttattattt ttactggttt
    20641 tacatcccct tctattctct ttttagcctt gcttggacag ttgtttcagt tctgtttttc
    20701 aataccgtct tgagaaatgt gacagatatc aagttatggg gcatttggtt tctttttatt
    20761 ctgctagcta ttggtatgaa ttggttaact tattcctgtt tcaaagaaat gtttcgcttg
    20821 agacaggaac tagggaagtc taagggtgga aggcattgat ttatatcggt ttctatttgt
    20881 aggaggtggc cttatggtac ctctaaaatc atttattaca cgctattcca aggtttatat
    20941 tggtaataac atttaataga acgaaactaa agaaaacaat ttaaaagagg aggtttgtga
    21001 tggaacactt gtttaaaatg ataatcttat taccctgttt ttactttttc agctggattg
    21061 acaaggataa tagagaaagt aaatttttcc caatttttta ctatttttac tggatttaca
    21121 tcaccctcta tgctcttttt agccttgctt ggacagtttt ttcagttctg tttttcaata
    21181 tcgtcttgag aaatttgaca gatatcaagt tatggggtat ttggctatta ttactactta
    21241 tcgcttttgc tagtgattgg ttagcctatg tctttttcaa aaaaatgatt cgcttgaggc
    21301 gggaactagg gaaatctaaa ggcggaaggc attgatttat actcttcgaa aatctcttca
    21361 aaccacgtca acgtcgcctt ggattatata tgtaactgac ttcgtcagtc ttatctacaa
    21421 cctcaaagca gtgctttgag caacttgcgg ctagtttcct agtttgctct ttgattttca
    21481 ttgagtatta tattactttc tatttgtagg aggtggctta tgaagattcc tctcttaact
    21541 ttggcaaggc ataaatttgt ttatgtctta cttactttgc tttttcttgc tttggtttat
    21601 cgtgacgttt tgatgactta tttctttttt gatattcatg cgcccgatct agctaaattc
    21661 gatggacaag caattaaaaa tgacttatta aaatcagcat tagattttcg tattctccag
    21721 ttcaatctag gtttttatca atcatttatt attccaatca tcattgtttt gctaggtttt
    21781 caatatattg agctgaaaaa taaagtttta cgattgagta ttggaagaga agtgagctat
    21841 caagggttaa aaagaaagtt gactttgcaa gttgcaagta tcccttgttt gatatattta
    21901 gtgactgtgc tgacaattgc aattataacc tatttccttg ggactttttc tcctcttgga
    21961 tggaattctc tattttctga tggaagtggt ttacaaagac tcctagatgg agagataaaa
    22021 agctatttgt tctttacttg tgtcctacta atcggtattt tcatcaatgc aatctatttt
    22081 ttacaaatag ttgattatgt ggggaatgtg actcgttcgg caatcgccta tttgatgttt
    22141 ctttggcttg gttctatatt actctatagt accttg
//
