LOCUS       NZ_FEOS01000008        18210 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 2842STDY5881910, whole genome
            shotgun sequence.
ACCESSION   NZ_FEOS01000008
VERSION     NZ_FEOS01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900036145.1-RS_2024_12_12
            Annotation Date                   :: 12/12/2024 02:11:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,245
            CDSs (total)                      :: 2,193
            Genes (coding)                    :: 2,004
            CDSs (with protein)               :: 2,004
            Genes (RNA)                       :: 52
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 85 of 189
            Pseudo Genes (incomplete)         :: 105 of 189
            Pseudo Genes (internal stop)      :: 56 of 189
            Pseudo Genes (multiple problems)  :: 48 of 189
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 81782
            Orig. end                         :: 99992
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FEOS01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18210
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..18210
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18210
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10876](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1608..2351
                     /gene="srtA"
                     /locus_tag="A1178_RS06580"
                     /old_locus_tag="ERS515165_01298"
     CDS             1608..2351
                     /codon_start=1
                     /gene="srtA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /locus_tag="A1178_RS06580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01298"
                     /product="sortase SrtA"
                     /protein_id="WP_000078846.1"
                     /transl_table=11
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWN
                     TNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELE
                     MNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNG
                     MKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDL
                     KETKDYSQTSDEILTAFNQPYKQFY"
     misc_feature    2428..2442
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.52"
                     /tool="antismash"
     gene            2595..3392
                     /locus_tag="A1178_RS06585"
                     /old_locus_tag="ERS515165_01299"
     CDS             2595..3392
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="A1178_RS06585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01299"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000625730.1"
                     /transl_table=11
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLEAIL
                     ANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            3540..4799
                     /locus_tag="A1178_RS06590"
                     /old_locus_tag="ERS515165_01301"
                     /pseudo=""
     CDS             3540..4799
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="A1178_RS06590"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01301"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            4895..6169
                     /locus_tag="A1178_RS06595"
                     /old_locus_tag="ERS515165_01302"
     CDS             4895..6169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="A1178_RS06595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01302"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_001002625.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEVQL
                     LENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     misc_feature    4937..4948
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            6179..7057
                     /gene="truB"
                     /locus_tag="A1178_RS06600"
                     /old_locus_tag="ERS515165_01303"
     CDS             6179..7057
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="A1178_RS06600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01303"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013241.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     gene            7298..7600
                     /locus_tag="A1178_RS06605"
                     /old_locus_tag="ERS515165_01305"
     CDS             7298..7600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="A1178_RS06605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01305"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985089.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     misc_feature    complement(7654..7668)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            7708..8346
                     /gene="udk"
                     /locus_tag="A1178_RS06610"
                     /old_locus_tag="ERS515165_01306"
     CDS             7708..8346
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="A1178_RS06610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01306"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            8474..9814
                     /gene="xseA"
                     /locus_tag="A1178_RS06615"
                     /old_locus_tag="ERS515165_01307"
     CDS             8474..9814
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="A1178_RS06615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01307"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000417464.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     misc_feature    complement(8514..8528)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.47"
                     /tool="antismash"
     gene            9792..10004
                     /locus_tag="A1178_RS06620"
                     /old_locus_tag="ERS515165_01308"
     CDS             9792..10004
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="A1178_RS06620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01308"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            10001..10876
                     /locus_tag="A1178_RS06625"
                     /old_locus_tag="ERS515165_01309"
     CDS             10001..10876
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="A1178_RS06625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01309"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_000743815.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-57, bitscore:
                     186.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFETESIV
                     SVVESLRING"
     gene            10869..11684
                     /locus_tag="A1178_RS06630"
                     /old_locus_tag="ERS515165_01310"
     CDS             10869..11684
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="A1178_RS06630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01310"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041080.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEAGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            11677..12108
                     /locus_tag="A1178_RS06635"
                     /old_locus_tag="ERS515165_01311"
     CDS             11677..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="A1178_RS06635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01311"
                     /product="arginine repressor"
                     /protein_id="WP_001034415.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            12115..13782
                     /gene="recN"
                     /locus_tag="A1178_RS06640"
                     /old_locus_tag="ERS515165_01312"
     CDS             12115..13782
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="A1178_RS06640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01312"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923608.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            13784..14512
                     /locus_tag="A1178_RS06645"
                     /old_locus_tag="ERS515165_01313"
     CDS             13784..14512
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="A1178_RS06645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01313"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_000133329.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQAQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            14591..16414
                     /gene="lepA"
                     /locus_tag="A1178_RS06650"
                     /old_locus_tag="ERS515165_01314"
     CDS             14591..16414
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="A1178_RS06650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01314"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047216.1"
                     /transl_table=11
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(16495..16737)
                     /locus_tag="A1178_RS13445"
                     /old_locus_tag="ERS515165_01315"
     CDS             complement(16495..16737)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1178_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS515165_01315"
                     /product="hypothetical protein"
                     /protein_id="WP_000693249.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSSKHGFEVVDETDEVSS
                     KHGFEVVDETDEVSNHTYGKATLTWFEEIFEEYKN"
     gene            16918..17394
                     /locus_tag="A1178_RS06660"
                     /old_locus_tag="ERS515165_01316"
                     /pseudo=""
     CDS             16918..17394
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /locus_tag="A1178_RS06660"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01316"
                     /product="PTS sugar transporter subunit IIA"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVLDYFFDKNLVFCLEADNQE"
     gene            17432..17734
                     /locus_tag="A1178_RS06665"
                     /old_locus_tag="ERS515165_01317"
     CDS             17432..17734
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /locus_tag="A1178_RS06665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01317"
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="WP_000590581.1"
                     /transl_table=11
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVNE
                     DLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            17742..>18210
                     /locus_tag="A1178_RS06670"
                     /old_locus_tag="ERS515165_01318"
                     /pseudo=""
     CDS             17742..>18210
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="A1178_RS06670"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="ERS515165_01318"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGGR
                     KPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQWVEVTLVQSGVTISRTP
                     LSSEDTVMIDATEVQINRPKKRISELFW"
ORIGIN
        1 gcagtacgtg atgagtcaaa ccgtgaaggt gttcgatttg ttattgaagt caagcgcgac
       61 gcctcagcca atgttattct caataacctc ttcaaaatga cccaaatgca aaccaatttt
      121 ggtttcaata tgctcgctat ccaaaatggt ataccgaaaa ttttgtctct tcgtcagatt
      181 ttggatgctt atatcgagca ccaaaaagaa gtggttgttc gtcgtacacg ttttgataag
      241 gaaaaagcgg aagcgcgcgc tcatatctta gaaggtctct tgattgcgct agaccatatc
      301 gacgaagtga ttcgtatcat ccgtgctagt gaaacggatg cggaagctca agctgagttg
      361 atgagcaagt ttaagctttc tgaacgtcaa agtcaagcta tccttgatat gcgtcttcgt
      421 cgtttgacag gtttggaacg cgataagatt caatctgagt atgatgacct cttggctctg
      481 attgcggatt tagcagatat tcttgctaag cctgaacgtg tttctcaaat tatcaaagac
      541 gaattggatg aagttaaacg taaattttct gataagcgcc gtacagagtt gatgattgga
      601 caggtcttga gtctcgagga tgaggacttg attgaagaat cggatgtctt gattaccctt
      661 tctaacagag gctacattaa gcgtttggat caggacgagt tcactgctca aaaacgtggg
      721 ggtcgtggtg tccaaggaac gggagtgaaa gatgatgact ttgttcgtga gttagtgtca
      781 actagcaccc atgatcatct gctcttcttc acaaacaagg gacgtgtcta tcgtcttaaa
      841 ggttatgaaa ttcctgagta tggtcggact gccaaagggc taccagtagt caatctcttg
      901 aaattggatg aagacgaaag tattcagacg gttatcaatg ttgagtctga tcgcagtgat
      961 gatgcttatc tcttctttac aacccgtcac ggtattgtga agagaactag tgttaaggag
     1021 tttgccaata ttcgtcaaaa tggtctcaaa gcgctgaatt taaaggatga agatgagtta
     1081 atcaatgtct tgttggcaga aggagatatg gatattatca ttggtaccaa gtttggttat
     1141 gcagttcgct ttaatcaatc agccgttcgt ggtatgagtc gtatcgccac tggtgtgaaa
     1201 ggtgttaacc ttcgtgaagg agacacagtt gttggtgcca gcttgattac tgatcaagat
     1261 gaggttctta ttatcacaga aaaaggatat ggtaagcgta cagtcgctac tgaataccca
     1321 acaaaaggtc gtggtggtaa gggaatgcag acagctaaaa ttaccgaaaa aaatggcttg
     1381 ctggccggtc ttatgactgt tcaaggggat gaggatttga tgattatcac tgatacaggt
     1441 gtcatgattc gaaccaatct tgccaatatt tcacaaacag gacgtgcaac tatgggagtt
     1501 aaagtaatgc gcctggatca agatgctcag atagtgactt tcacaacggt tgcggtggca
     1561 gaaaaagaag aagttgggac agaaaacgaa acagaaggtg aagcataatg tctcaaaaaa
     1621 ataataaaaa gaaaaacaag cgaaaaaatc tgctgacaaa tatcctagca ggatttctga
     1681 tattactgtc actggctttg atttttaata ctcaaattcg aaatattttc atagtctgga
     1741 ataccaataa gtatcaagtt agccaggtat caaaagaaaa attagaagaa aatcaggata
     1801 cagaaggcaa ttttgacttt gattctgtca aagctatctc ttcggaagct gttctaactt
     1861 ctcaatggga tgctcaaaaa ttaccagtta ttgggggaat tgcaattcct gaattggaaa
     1921 tgaatttgcc gatttttaaa ggacttgata atgttaatct cttctacgga gctggtacaa
     1981 tgaaacgcga gcaagtaatg ggagaaggaa attatagtct agctagtcac catatctttg
     2041 gtgttgataa tgctaataaa atgttatttt ctcctttaga taatgctaaa aatggcatga
     2101 agatttatct aactgataaa aataaagttt atacttatga aatacgtgaa gtcaaacgtg
     2161 tgacaccaga tcgtgttgat gaagttgatg atagagatgg ggtcaatgaa atcacattag
     2221 taacctgtga agaccttgct gctacagaac gtattattgt caaaggtgat ttgaaagaaa
     2281 caaaagatta ttcacaaaca tctgatgaaa tcctaacagc tttcaatcaa ccatataaac
     2341 aattttatta atacaaatca gtgaaatcat ggatttcact gattttttaa gattttcata
     2401 aaaatatagt aaaatgaaat aagaatagga ctaatcgttc aggacagtca aatcgatttc
     2461 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat aaacttttat
     2521 gaaatacaga aaacgcttcc taaaacctaa agtttgtgat ataattatca agaaaaaaga
     2581 tttaggagtt tattatgatt tcttcagaat ttatctcaaa gattgaattt gcttgcaata
     2641 agaaagaaag tctttatagt caaagcaaat ttaagtatgc gattcgttcg atattcgcag
     2701 gtgcattttt aaccttcagt actgctgcag gtgcagttgg ggctgacttg attaataaaa
     2761 ttgcaccagg tagtggacgc ttcctctttc cattcgtttt tgcttggggc ttggcctaca
     2821 ttgttttttt gaatgccgag ttggtcactt caaacatgat gttcttgact gctggtagtt
     2881 tcttaaaaaa aatctcttgg agaaaaacag ctgagatttt actatactgt accttgttca
     2941 accttatcgg atccttgata gcagggtggg gctttgctca ttcggcagcc tatgcgaatc
     3001 tgacacacga tagtttcatc tcaggtgttg ttgagatgaa gttaggccgc tcaaatgaat
     3061 tggtcttgct tgaggcgatt ttggcaaata ttttcgtaaa tattgcgatt ctgtcattta
     3121 ttttggtcaa agatggtggt gccaaacttt ggcttgtgtt gtcagctatt tacatgtttg
     3181 tattcttaac aaacgagcac attgcggcga actttgcttc tttcgcgatt gtgaaattca
     3241 gtgttgctgc ggattcaatt gccaacttcg gtgttggaaa tatgcttcgc cactggggtg
     3301 tgactttcat cggaaacttt atcggaggag gcctcttgat gggtcttcca tatgccttcc
     3361 tcaataaaaa cgaagatact tatgtagatt aagaaaatga gcacgattga gtcgtgcttt
     3421 tttcattttc aaaataaggt aatagctatt tcttatatca aaatatagaa aactgatatt
     3481 tgtaaactat aactcaaggt gctacaatat ccttaataaa ataatatgga ggtcacctta
     3541 tgactcgtga ttttaaattt gaaactctac aactacatgc tggtcaagtt gtgactccag
     3601 ctactgagtc tcgtgcagtg ccgatttatc aaacaacatc ttttgttttt gatgacacgt
     3661 aggaaggtgc tgatctgttt gccttgagga aaccagggaa catttatact cgtatcacca
     3721 atcctacaac agctgccctt gaaggtggtg ttgaagcgct agcaacagca tcaggtatga
     3781 ctgcagtgac ttatacgatt ttggcgcttg cccatgctgg tgaccatgta gtggctgctt
     3841 cgactattta cggtggaacc ttcaatcttt tgaaagaacc ccttcctcgt tatggtatca
     3901 caacaacctt tgtcgatatt gataatttgg aggaagtaga agcagctatc aaagacaata
     3961 ccaagcttgt cttgattgaa accttgggta actccttgat taatattcca gacctggaaa
     4021 aactggcaga gattgctcat aaacatcaaa tcccacttgt gtcagacaat acttttgcaa
     4081 caccttattt gattaacgtc ttctctcatg gcgttgacat tgccattcac tctgcgacta
     4141 agtttatcgg tgggcatggt acaactattg gaggaataat tgtcgatagt ggtcgttttg
     4201 actggacggc ttcagggaaa ttccctcaat ttgttgacga gggttcaagc tgccacaatt
     4261 tgagctatat tcgtgatgtg ggtgcagcaa cctttattat agctgttcga gttcaattgc
     4321 ttcgtgatac aggtgcagcc ttgtcaccat tcaatgcttt cctcttgcta caaagacttg
     4381 aaactctttc acttcgtgtg gaacgccatg tacaaaatgc tgagacaatt gttgattttc
     4441 ttgtcaacca tcctaaggta gaaaaggtaa attatccaaa acttgcagat agtccttatc
     4501 atgccttggc tgagaaatac ttgccaaaag gtgtcggttc aatctttacc ttccacgtca
     4561 aaggtgacga ggaagaagca cgcaaggtca ttgataattt agaaatcttt tctgaccttg
     4621 caaacgcggc agatgctaaa tcgcttgttg tccatccagc aacaaccact cacggtcaat
     4681 tgtcagaaaa agacctagaa gcagcaggtg tcacaccaaa ccaaattcgt ctgtcaatcg
     4741 gtcttgaaaa tgtagaagat ttgattgaag acttacgctt ggccttggaa aaaatttaaa
     4801 gtaaaagaag ataaacagtg ggttttgact cactgttttt gattttccct caggcatgat
     4861 ataatggtta cagaagtcta gaaagaggaa tgtaatgaac gaaatcaaat gtcccaactg
     4921 tggggaagtc tttacagtaa atgaaagcca gtatgctgaa cttttgtccc aagtgagaac
     4981 ggcagagttt gataaggaac tacacgatag gatgaggcag gaactggcct tggctgagca
     5041 aaaggctatg aatgagcaac agactaaact ggctcagaag gatcaagaaa ttgcgcaatt
     5101 acagagtcag atccaaaact ttgatacaga aaaagaattg gccaagaaag aggttgaaca
     5161 gacaagccat gaggctctct tggctaagga caaggaagta cagctcttag aaaatcagtt
     5221 ggctaccttg cgtttggagc atgaaaatca actacaaaag accctttctg acctagaaaa
     5281 agaacgggat caggttaaaa accaactact tttgcaggaa aaggaaaatg aattatcttt
     5341 ggcttctgtt aagcaaaact acgaagccca gctcaaggca gctagtgaac aagtcgagtt
     5401 ttataagaat tttaaggctc aacaatctac aaaagcgatt ggggaaagcc tagaacagta
     5461 tgcagagagt gagtttaaca aggttcgtag tttcgccttt ccaaatgctt actttgagaa
     5521 ggataacaag gtctcttcgc gtgggtctaa aggggacttt atcttccgtg agtgtgatga
     5581 aaatggagtt gaaatcattt ctatcatgtt tgagatgaaa aacgaagcgg acggaacaga
     5641 gaagaagcac aagaatgcag atttttacaa ggaattggac aaggaccgtc gggagaagaa
     5701 ctgtgagtat gccgttttgg tgaccatgct tgaggctgat aatgactact ttaacacagg
     5761 gattgttgac gtcagtcacg agtatgaaaa aatgtatgtt gttcgtcctc aattctttat
     5821 ccaattgatt ggtctcttac gtaatgcggc gctaaattcc ctaaaataca agcaggagtt
     5881 ggccttggtt cgcgagcaaa atattgacat tacgcatttt gaggaagatt tggatgcctt
     5941 taagctagct tttgctaaga actataattc agcttcgact aactttggaa aagctattga
     6001 tgaaatcgac aaggccatca aacgcatgga agaggttaag aaattcctga ccacatctga
     6061 aaaccaactc cgtttagcta acaacaaatt ggaagatgtc tctgttaaaa aattgacccg
     6121 gaaaaatcca acaatgaaag cgaagttcga agcactgaag ggggagtaga aagcaaaaat
     6181 gaacggtatt attaacttaa aaaaggaagc aggaatgacc tcgcatgatg cggtttttaa
     6241 actgcgtaag attttgggaa ccaagaaaat tggtcatggt ggaaccttgg atccggatgt
     6301 ggtgggtgtt ttgccgattg cggttggcaa ggcgacacgc atggtcgagt ttatgcagga
     6361 cgagggtaag atctatgagg gggaaatcac tctgggctat tccacgaaga ctgaggatgc
     6421 tagtggggaa gtggtcgcag aaacccctgt tttgtctctc ttggatgaaa agcttgttga
     6481 tgaagcgatt gctagcttga ctgggcctat tactcagatt ccccctatgt attcggcagt
     6541 taaggttaat ggtcgcaagc tctatgagta tgcgcgtgct ggtcaggaag tggagcgtcc
     6601 agaacgtcag gtgaccattt atcaatttga gcgaacaagt ccgatttctt atgatggcca
     6661 acttgcccga ttcacttttc gtgtaaaatg cagtaaaggg acgtacatcc gtactttgtc
     6721 agttgatttg ggtgaaaagc ttggttatgc ggctcatatg tcccatttga ctcgtactag
     6781 tgctgctggc ttacaattag aagacgctct tgccttggag gaaattgctg aaaaagtaga
     6841 ggctgggcaa ttagattttc tccatccttt agagattggg acaggtgacc ttgtcaaagt
     6901 tttcctaact ccagaagagg ctacagaagt tcgctttggt cgttttattg agctagacca
     6961 aacggacaaa gaactggctg cctttgaaga tgataaattg ttagccattc tagaaaaacg
     7021 gggcaatctc tataagccaa ggaaggtttt tagctagatc gtttaggaat aaaaatcggg
     7081 tgatagataa caattgcttg ataaaacccc atactaatag tagaatggtt ttgggaatta
     7141 taatattcca attgttgcga gttgtaggta ctcaaataat ctatatagaa atttagaggt
     7201 gtgaaatgaa gcaatttaaa attctttcag ataaatattt agagtccatt acaggttctg
     7261 atgggaactt aggcccagga tttggtgtga taattccatg atgcgaaatg agtttcgaga
     7321 aagggtggag caacttcttc aacaaaaaga aataaatgaa aatagtgagt tgagtcacct
     7381 gtttcgtctt gctatacaaa atttagacag aaatgaaaaa taccaatcgg tcatggccaa
     7441 tttgagtcaa gggttgtcac tttacctcat gacgcatcat taccaggcac ctaagtctgt
     7501 cattgatttt ggtttatgga ttgccaaagc tcctagccag gaaagaggga gactggcttt
     7561 cttgcagatg cttgctcaaa ccctacaggg ctttcgttaa aactgtcgaa catcagaggg
     7621 aagactctgg tgttttttgc tgatgagact ataaattttg taaaaaatgt gatagaatag
     7681 acgacggata aaataacgga ggatagcatg caaaatagac caatcattat tggagtgaca
     7741 ggtggttctg gtggtggtaa aaccagtgtt tcaagagcca ttttatcgca ttttcctgat
     7801 gaaaagattt ccatgattga gcatgattca tactacaagg atcagtctca tttgaccttt
     7861 gaagagcgtg tcaaaaccaa ctatgaccat ccttttgcct ttgatacaga cttgatgatc
     7921 gagcagatta aggaattgtt ggcagggcgt ccggtggaca tcccgaccta cgactataca
     7981 gagcatacac ggagtagcaa gacctatcgt caggaacctc aagatgtctt tatcgttgag
     8041 ggtattttgg tcttggagga caagcgtctg cgcgatttga tggatatcaa gatttttgtg
     8101 gatacggatg acgatgtgcg cattattcgt cgtatcaagc gtgatatgga ggagcgtggc
     8161 cgtagccttg atagcgttat taaccagtac ttaggtgtgg tcaaaccaat gtaccaccag
     8221 tttatcgagt caactaagcg ttatgctgat atcgtcattc ctgaaggggt tagcaatacc
     8281 gtggctatcg acctgttgac gaccaagatt gcaaagattt tggaagaagc tcgaaacagc
     8341 aaataatcac atgtggaggc cttgcctcct ttttctattt ttccctcata atggtacata
     8401 aatggagatt tttaggcata tttttggtat aataataccc atgaaagagc aagtaaatga
     8461 atagtaggtg gagatggaaa agtatttatc ggtaacaact ttgaccaagt atctgaaaat
     8521 gaaattcgat aaagacccat acttggaacg ggtctattta actggtcaag tttccaactt
     8581 tcgtaaacga cctactcacc aatatttctc cctaaaggat gaccatgcag ttattcaagc
     8641 gaccatctgg tctgggattt atcagaaatt agggtttgac ctggaagaag gaatgaagat
     8701 caatgtgatt gggcgtgtac aggtctatga accaagtggt agctactcca tcatcattga
     8761 aaaagctgag cctgatgggg ttggggcgct tgcgattcag tttgaacaac ttaagaaaaa
     8821 attgacagaa gaaggcctgt ttcaagaacg cttcaagcaa gctctgcccc aattttctaa
     8881 gagaattggt gtagtaacca gccgtagtgg agccgttatt cgagatatta tcacgaccgt
     8941 cagcaggcga ttcccaggtg ttgacatcct tctttatccg accaaggttc aaggtgaagg
     9001 ggctgcggag gaaattgcta gaaatattgc gcgtgctaat caacgggacg atttggattt
     9061 gctcattatt ggtcgtggag gtggttctat tgaggatctc tgggccttta acgaagaaat
     9121 tgtggtacga gctatttttg aatctcgttt gccagttatc tctagtgtgg ggcatgagac
     9181 ggatgtgacc ttggcagatt ttgtggcaga tcgacgcgct gcaacgccaa cagcggcggc
     9241 tgaactggca acacctgtga ccaagttgga tgtattagct catttgcaaa atcaggaaaa
     9301 acggatggta acggcagtcc gaaatgttct atctaagaaa caagaggctt tgaaaaaatg
     9361 cagtcagtct gttatcttta gacaacctga gcgcttgtat gacggttatt tgcaacgctt
     9421 ggaccaactg caactgcgtt tgaaacaaag tttgcgaact cggatttctg ataacaaaca
     9481 attagttcaa gcaagaactc atcaattagt acaattatca cctgttacca aaatccaacg
     9541 ctatcaagac cgtttaggac agttggacaa gctcttaggt agccaaatgg cgttagttta
     9601 tgacgccaag gttgctgagg ccaagcgact ttcggaagct ttgctcatgt tggatactag
     9661 ccgaatcgtg gcgcgtggtt atgctattgt caaaaaagaa gagtccgttg tagattcggt
     9721 tgagagtttg aagaaaaaag accaagtaac gcttttgatg cgagatggtc aagtagaatt
     9781 agaggttaaa gatgtcaaaa caaaagaaat ttgaggaaaa tctagcagaa ctggaaacca
     9841 ttgtccaaag tttggaaaat ggtgaaattg ctctggaaga tgcgattact gcctttcaaa
     9901 agggcatggt cttgtcaaaa gagctccaag ctacgctgga caaggctgaa aagaccttgg
     9961 tcaaggtcat gcaagaagac ggaacagaaa gtgattttga atgaaaaagc aagaaaaatt
    10021 agctcttgtc gagtcggctt tggaagattt ttatggagac cagcagtttg cctctagttt
    10081 acgggagtct gttctctatt ctattcatgc tggtggcaag cgtattcggc cttttctctt
    10141 gttagaagtt ctggaagcct tgcaggttac catcaaacct gctcacgcgc aggtagctac
    10201 tgccttagag atgattcata cagggagctt gattcacgat gaccttcctg ctatggatga
    10261 tgacgattat cgaagagggc ggttaaccaa tcacaagaaa ttcggtgaag ctatggccat
    10321 tttggctgga gatgctttat tcttagaccc atatgccttg attgcgcagg cagatttgcc
    10381 aagtcagatc aaggtggact tgattgccaa cttatccctt gcttcaggta gtctgggtat
    10441 ggtggcaggg caagttttgg atatggaggg cgaacaccag cacttgtctc tggaagaact
    10501 tcagactatt catgccaata agactgggaa gttactagcc tatcccttcc aagcggcagc
    10561 tattatagct gaattgtcac ctgaaatgca ggtgaagctg aaaactgtgg gtgaattgat
    10621 tggacttgct tttcaagtca gagatgatgt actggatgtg acagctagtt ttgaggaaat
    10681 cggcaagaca cctcaaaagg atctgcaggc agaaaaatca acctatcctg ccttgttggg
    10741 cttggaagag tccattgcct tttgtaacca aaccctggat caagctaatg aaaaattaga
    10801 agaaattgcc cagcagcttc cctttgaaac agaatcgatt gtaagtgtag tagaaagttt
    10861 gagaatcaat ggctaaggaa agagtggatg tactagctta taaacagggg ttgtttgaaa
    10921 cgagagagca ggccaagcga ggtgtgatgg ctggcctagt cgtagcagtc cttaatggag
    10981 aacggtttga caagccagga gagaaaattc cagatgacac cgaattaaaa ctcaaggggg
    11041 agaaactcaa gtatgtcagc cgtggtggtt tgaaactgga aaaggccttg caggtctttg
    11101 atttgtcggt ggatggcgcg actacgattg atatcggggc ctctactgga ggttttaccg
    11161 atgtcatgct acagaatagt gccaagttgg tctttgcagt cgatgttggg accaatcagt
    11221 tggcttggaa attacgccaa gacccacgag ttgtcagcat ggagcagttc aatttccgct
    11281 atgctgaaaa gactgatttc gagcaggagc cgagctttgc cagtattgat gtgagtttca
    11341 tttcccttag tctgattttg ccagccttgc accgtgtctt ggctgatcaa ggtcaggtgg
    11401 tagcacttgt caaacctcag tttgaggcag gacgtgagca gattgggaaa aatggaatta
    11461 ttcgagatgt taagattcat cagaatgtcc ttgaatctgt aacagctatg gcagtagagg
    11521 caggtttttc agtccttggc ttggactttt ctcccatcca aggtggacat ggaaatattg
    11581 aatttttagc gtatttgaaa aaagaaaagt cagcaagcaa tcagattctt gctgagatta
    11641 aagaagcagt agagagggcg catagtcaat ttaaaaatga ataaaaaaga aagacttgaa
    11701 aaaattagaa gattggtgac agattatcaa atcggcacgc aagaagaaat tgtagaacat
    11761 ttgaaagaag caggtatcac tgccactcag gcgacggtat cccgagatat caaagagtta
    11821 ggtattgtca aaattccttt gagagacaac acctatgtct acgaattacc aaaatcaatc
    11881 gtaaaaagtc tgcaactggc tgaagacaat atcgaatcgg ctgaattgat ggataagatg
    11941 atcaatctcc aagttattcc aggaaatacg gcttttgtaa aagctcagtt aatcgagact
    12001 tttgcagaca agatttttag ctgtttgact gatgatagct cgattttagt cattgccaga
    12061 agtggaagtc tagcagagga aatctttgaa caagtaaaaa attggtaggt ctatatgtta
    12121 cttgaaattt cgataaaaaa ctttgccatt attgaggcta tttccctcaa ttttgaaaag
    12181 gggatgactg tcctgactgg tgaaacgggt gcagggaagt cgattatcat tgatgccatg
    12241 aatatgatgt tgggagctcg tgcgacgaca gatgttattc gtcatggtgt accaaaggca
    12301 gagattgagg ggcttttctc agttgagaat agtcgtcttt tacaggaaat ttttgatgag
    12361 caaggtttag aattaggtga tgaaattatc atccgtcggg aaatcttgca aaatggtcgt
    12421 agtatcagcc gtgtaaatgg tcagatggtt aatctgtctg ttttgcgagc tattgggcaa
    12481 catcttgtag atattcatgg tcagcatgac catgaggagt taatgcgtcc ccaactgcat
    12541 atccagatgt tggatgaatt tggtgatgcc gctttttggg acttgaaaga aacctatcaa
    12601 acgagttttg atgcctatcg gaaaatgcgc aagcaggttc tggaagtcaa gaaaaaccaa
    12661 caggaacaca aggcacgtat cgaaatgttg gaatttcaaa tggcagagat tgaggcagca
    12721 aacttgcagg ctggagaaga cttggctctc aatcaagagc gagataaact cctcaaccac
    12781 aaaaatattg cggatacact gaccaatgcc tacagtatgt tggacaatga agatttttca
    12841 agtctggcca atgttcgttc agccatgaat gacatggaaa gtgtcgaaga gtatgaccct
    12901 gaataccgtg aaatttcaag ctctctgtct gagacctact atgttttaga agacattagc
    12961 aaacgtttgg aagctatcat tgaggacctt gattttgatg gcaatcgcct catgcaggtt
    13021 gagaatcgtt tgcacctcct tcatactatt actcgtaagt atggtgggac tgttgatgat
    13081 gttttgcttt attttgctaa gattacggaa gaatacaatc tcttgacagg caataatctt
    13141 tcgtctgagg acatggaagc agagcttaag aagttggaag tcaatcttgt caatttggca
    13201 ggtcaacttg cttctgcccg tcataatttg gctcagcaac tcgaagctga gattaaacaa
    13261 gaactgcaag atctttatat ggaaaaagcc cagtttcagg ttcgttttag taagggaaaa
    13321 ttcagtcgtg agggaaatga aatggttgag ttttatattt caaccaaccc tggagaagac
    13381 tttaaaccct tggttaaggt tgcttctgga ggggaattat ctcgtctcat gttagccatt
    13441 aagtctgcct tttcacgtaa agaaggcaag actagcattg tctttgatga ggtggatacg
    13501 ggagtttcag gtcgtgttgc tcaagctatt gctcagaaaa ttcataaaat tggtcagcat
    13561 ggtcaggttt tggctatctc ccatttgcca caagtaattg cgattgcaga ttatcaattc
    13621 tttattgaga agattagtaa tgaccattca acggtttcga ctgttcgtct tttgacggtc
    13681 gaagagcgag tggaggaagt tgccaagatg ttggcaggtg atgatgtgac agaagcagcc
    13741 ctgacgcaag ccagagaatt gttgagaaac agggagaaat aagatgacag actattatgt
    13801 aattggagat gttcacggaa aagctgggat gctggaagac cttctcaaaa cctgggatgg
    13861 tcaggcccag ttgctctttc taggtgattt gattgacaga ggtgaggata gtcaccgtgt
    13921 tcttgaaatg gtcaaggact tggtggacaa tcaaggggct atctgtttgt ccggaaacca
    13981 cgagtatatg tttttgactt ggctagatga cccagaagaa agttatgacc attatcgtcg
    14041 caatggtgga gatacaacca ttaactctat cctaggtcgt cccttggatg caccagttga
    14101 tggagtagaa gatgccaagc gggttgccgc tgaagcggca gacttggtcg aattcattcg
    14161 tcaaatgcca tttgtagtag agacagacaa gtatatcttt gttcacgcag gtattgattt
    14221 gaccttggac gactggcatg aaacaacaga ttataaaaaa gtatggctta gaaaaccatt
    14281 ccacggagct gaaaatcata ctggaaaaac cattgtcttc ggtcatacac cggtctatgg
    14341 tttgttacag caagaacgcg gtacatctga gctttggact acagaagatg gcaagattgg
    14401 aatggatgga ggagctgttt atggtggtgt ccttcacggg attgtcttta cagaccaagg
    14461 aatgacagaa caccacttta tcgaaaatga cggctttgtc gctgaagatt agtactccta
    14521 gcagggtatg gtcttgtcaa aatatcaaaa acaatttata ataaatagat accctgaaag
    14581 gaagagaatc atgaacttag aagaattgaa aaaacgacag gggaagatcc gtaacttctc
    14641 tattatcgcc catattgacc acgggaaatc aactctagca gaccgcattt tggaaaaaac
    14701 agagacggtt tcaagtcgtg aaatgcaggc ccagcttttg gatagcatgg atctagagcg
    14761 ggaacgtgga attactatta agttgaatgc catcgagttg aattacactg caaaagatgg
    14821 ggaaacttat attttccact tgattgacac accagggcac gttgacttta cctatgaagt
    14881 ttcacgttcg ctagctgcct gtgagggtgc tattttggtg gtcgatgcgg ctcaaggaat
    14941 tgaggctcaa actcttgcca acgtttatct ggctttggat aatgatttgg aaatcatgcc
    15001 tatcattaat aaaattgacc tgccggctgc agatccggag cgcgtgcgta cagagattga
    15061 agatgtgatt ggtttggatg ccagtgaagc agttttggct tctgccaagg ctggtattgg
    15121 gattgaagaa atcctcgagc aaattgtaga aaaagtacca gcaccaacgg gtgatgtgac
    15181 ggcgccactt aaggccttga ttttcgactc tgtttacgat gcttaccgtg gggttatcct
    15241 ccaagtgcgt gtcatggacg gagtggtcaa acctggtgat aagattcagc tcatgagcaa
    15301 tagtaagacc tttgatgtgg ccgaagtcgg tatttttaca ccaaaagcgg ttggtcgtga
    15361 tttccttgcg actggtgatg ttggttacat tgcggcgtct atcaagacgg ttcaggatac
    15421 tcgtgtgggt gataccgtta ccttggcaac caatcctgcg gcagaaccat tacatggtta
    15481 taagcagatg aatcctatgg tctttgcggg tctctaccca atcgaatcaa acaagtacaa
    15541 tgacctgcgt gaagcgcttg aaaaattgca actgaatgat gctagtcttc agtttgaacc
    15601 agaaacatct caggcacttg gatttggttt ccgttgtgga tttcttggac ttctccatat
    15661 ggatgttatc caggaacgtt tagagcgtga gttcaatatt gacctcatca tgacagctcc
    15721 gtctgttatt tacaaagtta atttgaccga cggtgagtct atggatgtgt ctaacccatc
    15781 tgagtttcca gacccaacta agattgcgac cattgaagag ccttatgtca aggcgcaaat
    15841 catggtacca caggagttcg tcggagcagt aatggagcta gctcagcgta agcgtgggga
    15901 ctttgtgact atggactata ttgatgataa ccgtgtcaat gttatctatc aaattcctct
    15961 tgctgaaatt gtctttgact tctttgataa acttaagtct tcgacacgtg gttatgcaag
    16021 ctttgactac gaattgtcag aatatcgccc atctaagctg gtgaaaatgg atattcttct
    16081 caatggagat aaggtggatg ccctcagctt tatcgttcac aaggactttg cctacgaacg
    16141 tgggaaactc atcgttgata aactcaagaa aatcatccct cgccaacaat ttgaagttcc
    16201 aatccaagcg gctattggac acaagattgt cgctcgtact gatatcaagg cccttcgtaa
    16261 gaacgtactt gctaaatgtt atggtggtga cgtttctcgt aagcgtaaac tccttgaaaa
    16321 acaaaaagct ggtaagaaac gcatgaaatc catcggatca gttgaagttc cgcaagaagc
    16381 cttcctcagc gtcttgagta tggatgaaga ataagttatc agaaatgcct ttccttgttc
    16441 acaggaaatt tatataagaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    16501 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
    16561 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    16621 ttcatctaca acctcaaaac catgttttga gctgacttcg tcagtttcat ctacaacctc
    16681 aaaactgtgt tttgaacaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    16741 gtattagaac agaaaaaatg cttggagtat ttgtttgtgt gtttactttt atataacaaa
    16801 ctataaacac aacaaaaata taaaaaaaga gacaaaaaag aacagaaagt aattaacaac
    16861 gatttcatat agtgttatac ttatagcata aagttaatgg aaagaaggga aaaccttatg
    16921 gtattagatt atttctttga caaaaacctt gtgttttgct tagaagcgga taatcaagaa
    16981 taactctttg atcaggtagc aagcttgttg gaggaacgag aaattgtaac tccaacttat
    17041 cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta
    17101 ggaaaggact tgccaaatgt agcgattcct catacagata ttgttcataa tctagctgag
    17161 aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat
    17221 aaggaagtag aagtatccct actcttcttt atcattaaca attcaagttc aagtcaaaca
    17281 aatattctgg ctcagttgat ggactttttc acaggaaatg gacatcttga agatctatca
    17341 aaaatttccg aaccagaaaa actttatgct tacattgctg aagcaaccgc ttaatcttgt
    17401 ctattaaaaa ataaaatcgg aggaaatcca aatgattaaa attcttgctg cctgcggtgc
    17461 aggtgttaac tcaagttacc aaattaaaag tgctctagaa gaagaacttt caaaccgtgg
    17521 ttatgatgtt cactgtgatg cagtcatggt gaaagatgta aacgaagacc ttatgaaagg
    17581 ttacgatatc tttacaccaa tcgctgcaac agaccttggt tttgaaccag gtatcccagt
    17641 tatcgaagct gggccaatct tattccgtat cccagcaatg agcgttccag tatttgacaa
    17701 tattagactt cctgcgaaac aaaatatggt atagtagttc tatgaatgat gaagcaagta
    17761 aacaactaac tgatgcacga tttaagcgtc ttgttggtgt tcagcgtact acttttgaag
    17821 agatgttagc tgtattaaaa acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac
    17881 ctaaattaag cctagaagac cttcttatgg ccactcttca atatgtgcga gaataccgca
    17941 cttatgaaga aattgcggct gattttggta tccacgaaag caacttaatc cgtcggagcc
    18001 aatgggttga agtaactctt gttcaaagtg gtgttacgat ttcaagaact cctctcagtt
    18061 ctgaggacac ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa
    18121 ttagcgaatt attctggtaa aaagaaattt cacgctatga aggctcaagc gattgtcaca
    18181 agtcaaggga gaattgtttc tttggatatc
//
