LOCUS       NZ_FDFR01000008        22991 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 2842STDY5753301, whole genome
            shotgun sequence.
ACCESSION   NZ_FDFR01000008
VERSION     NZ_FDFR01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900022985.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 02:12:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,313
            CDSs (total)                      :: 2,259
            Genes (coding)                    :: 2,086
            CDSs (with protein)               :: 2,086
            Genes (RNA)                       :: 54
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 71 of 173
            Pseudo Genes (incomplete)         :: 93 of 173
            Pseudo Genes (internal stop)      :: 58 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:29:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 20965
            Orig. end                         :: 43956
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FDFR01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22991
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22991
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22991
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12991](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12991
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(279..293)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.04"
                     /tool="antismash"
     gene            complement(836..2206)
                     /locus_tag="A1O50_RS09270"
                     /old_locus_tag="ERS409084_01809"
     CDS             complement(836..2206)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /locus_tag="A1O50_RS09270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01809"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_061751191.1"
                     /transl_table=11
                     /translation="MNKKRTVDLIHGPILPSLLSFAFPILLSNIFQQLYNTADVLIVGR
                     FLGQESLAAIGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGA
                     LLSILVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIG
                     DSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPE
                     LLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQTAARR
                     IMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGFRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIEL
                     IGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILETKVQS"
     gene            complement(2512..3678)
                     /gene="recA"
                     /locus_tag="A1O50_RS09275"
                     /old_locus_tag="ERS409084_01810"
     CDS             complement(2512..3678)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="recA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /locus_tag="A1O50_RS09275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01810"
                     /product="recombinase RecA"
                     /protein_id="WP_001085463.1"
                     /transl_table=11
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGER
                     AEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAA
                     FIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALV
                     PRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETT
                     PGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMY
                     GEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFDEIDKQV
                     RSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(3733..4989)
                     /locus_tag="A1O50_RS09280"
                     /old_locus_tag="ERS409084_01811"
     CDS             complement(3733..4989)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /locus_tag="A1O50_RS09280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01811"
                     /product="competence/damage-inducible protein A"
                     /protein_id="WP_000642704.1"
                     /transl_table=11
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDN
                     EVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIFFA
                     LRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPMVLN
                     QLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTK
                     ASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAA
                     AESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVSEFTAQK
                     MAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADV
                     RHIAVMHAFNLVRKALLSD"
     misc_feature    complement(5015..5028)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    complement(5016..5029)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     gene            complement(5074..6090)
                     /gene="brpA"
                     /locus_tag="A1O50_RS09285"
                     /old_locus_tag="ERS409084_01812"
     CDS             complement(5074..6090)
                     /codon_start=1
                     /gene="brpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /locus_tag="A1O50_RS09285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01812"
                     /product="biofilm formation/cell division transcriptional
                     regulator BrpA"
                     /protein_id="WP_000239278.1"
                     /transl_table=11
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGEE
                     TKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDILTR
                     IESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVGGIT
                     VNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQREVI
                     QKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQQLQGE
                     GEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVGDEDN"
     gene            complement(6098..6616)
                     /locus_tag="A1O50_RS09290"
                     /old_locus_tag="ERS409084_01813"
     CDS             complement(6098..6616)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /locus_tag="A1O50_RS09290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01813"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000455536.1"
                     /transl_table=11
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSEE
                     MEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNGLG
                     SLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGKFID
                     VYLMGKLID"
     gene            complement(6606..7049)
                     /gene="tsaE"
                     /locus_tag="A1O50_RS09295"
                     /old_locus_tag="ERS409084_01814"
     CDS             complement(6606..7049)
                     /GO_process="GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tsaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /locus_tag="A1O50_RS09295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01814"
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="WP_000288230.1"
                     /transl_table=11
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLAK
                     GLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWGNL
                     LGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(7135..7755)
                     /locus_tag="A1O50_RS09300"
                     /old_locus_tag="ERS409084_01815"
     CDS             complement(7135..7755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /locus_tag="A1O50_RS09300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01815"
                     /product="hypothetical protein"
                     /protein_id="WP_000839909.1"
                     /transl_table=11
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVS
                     GICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQEL
                     VDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTIVSL
                     LIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     misc_feature    complement(8025..8038)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(8084..8101)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            complement(8138..9001)
                     /locus_tag="A1O50_RS09305"
                     /old_locus_tag="ERS409084_01816"
     CDS             complement(8138..9001)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /locus_tag="A1O50_RS09305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01816"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001093641.1"
                     /transl_table=11
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSAD
                     LLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERSTF
                     LTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFYSLV
                     GREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEALETI
                     ELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMKIENYL
                     KELDTV"
     gene            9193..9363
                     /locus_tag="A1O50_RS13755"
                     /old_locus_tag="ERS409084_01817"
     CDS             9193..9363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /locus_tag="A1O50_RS13755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01817"
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="WP_001227862.1"
                     /transl_table=11
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQK
                     KSNGLDVGKAD"
     misc_feature    complement(9195..9210)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.81"
                     /tool="antismash"
     gene            9466..9690
                     /gene="pneA1"
                     /locus_tag="A1O50_RS09315"
                     /old_locus_tag="ERS409084_01818"
     CDS             9466..9690
                     /codon_start=1
                     /gene="pneA1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /locus_tag="A1O50_RS09315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01818"
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="WP_000181087.1"
                     /transl_table=11
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIILK
                     SAAASSKVCISAAVSGIGGLVSYNNDCLG"
     CDS_motif       9466..9552
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTNFNSNEKFCGKSLKSLSADEMSLIYGA"
                     /locus_tag="A1O50_RS09315_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9553..9690
                     /prepeptide="core"
                     /locus_tag="A1O50_RS09315_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.40"
                     /molecular_weight="4315.8"
                     /monoisotopic_mass="4313.2"
                     /core_sequence="SDGAEPRWTPTPIILKSAAASSKVCISAAVSGIGGLVSYNNDC
                     LG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTNFNSNEKFCGKSLKSLSADEMSLIYGA"
                     /leader_location="[9465:9552](+)"
                     /alternative_weights="4333.9"
                     /alternative_weights="4351.9"
                     /alternative_weights="4369.9"
                     /alternative_weights="4387.9"
                     /alternative_weights="4405.9"
                     /alternative_weights="4424.0"
                     /alternative_weights="4442.0"
     gene            9697..9885
                     /gene="pneA2"
                     /locus_tag="A1O50_RS09320"
                     /old_locus_tag="ERS409084_01819"
     CDS             9697..9885
                     /codon_start=1
                     /gene="pneA2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /locus_tag="A1O50_RS09320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01819"
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="WP_000786759.1"
                     /transl_table=11
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFIA
                     SYLGSAQTRCGKDNKKK"
     CDS_motif       9697..9771
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNDFVIGKSLKELSLEEMQLVYGG"
                     /locus_tag="A1O50_RS09320_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9772..9885
                     /prepeptide="core"
                     /locus_tag="A1O50_RS09320_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.30"
                     /molecular_weight="3743.2"
                     /monoisotopic_mass="3741.0"
                     /core_sequence="TDGADPRSTIICSATLSFIASYLGSAQTRCGKDNKKK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNDFVIGKSLKELSLEEMQLVYGG"
                     /leader_location="[9696:9771](+)"
                     /alternative_weights="3761.2"
                     /alternative_weights="3779.2"
                     /alternative_weights="3797.3"
                     /alternative_weights="3815.3"
                     /alternative_weights="3833.3"
                     /alternative_weights="3851.3"
                     /alternative_weights="3869.3"
     gene            10001..12991
                     /locus_tag="A1O50_RS09325"
                     /old_locus_tag="ERS409084_01820"
     CDS             10001..12991
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /locus_tag="A1O50_RS09325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01820"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_000875571.1"
                     /sec_met_domain="DUF4135 (E-value: 2e-91, bitscore: 299.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.1e-52, bitscore:
                     170.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSIIS
                     EKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKHPQ
                     RINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPWIVK
                     PLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESCLRFY
                     TYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPK
                     NLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLPEYYYNF
                     GVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTR
                     TLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNL
                     PVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSY
                     ASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNIN
                     EIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNL
                     SNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMY
                     RGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSII
                     EDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERV
                     LRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVP
                     REKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDT
                     SMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIV
                     IPSLLEI"
     misc_feature    13191..13204
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.84"
                     /tool="antismash"
     gene            13341..14045
                     /locus_tag="A1O50_RS09330"
                     /old_locus_tag="ERS409084_01821"
     CDS             13341..14045
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /locus_tag="A1O50_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01821"
                     /product="flavodoxin family protein"
                     /protein_id="WP_001033170.1"
                     /transl_table=11
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNSE
                     LEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFIER
                     IGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKDIAE
                     AQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRLFEAN
                     SLEEWYYVENIK"
     gene            14026..14955
                     /locus_tag="A1O50_RS09335"
                     /old_locus_tag="ERS409084_01822"
     CDS             14026..14955
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /locus_tag="A1O50_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01822"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_000912954.1"
                     /transl_table=11
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISIT
                     LHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKNSD
                     RNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAIREI
                     VLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVKGEGS
                     AFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSKNNKYL
                     EKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            14952..17060
                     /locus_tag="A1O50_RS09340"
                     /old_locus_tag="ERS409084_01823"
     CDS             14952..17060
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /locus_tag="A1O50_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01823"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_000701298.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.2e-38, bitscore:
                     123.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRSG
                     YSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYILDP
                     AKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFFVTA
                     LLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVASLKYI
                     MDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDLLMIVV
                     YAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITSEVISKN
                     SDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLTLIVGVNI
                     KTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNTKSELIPER
                     VSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSGKSTLAKILL
                     GLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTFGHFVSDEELM
                     TNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKPSVVVLDEATSS
                     LDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEIGTHRELLELGGI
                     YKQLYSNN"
     gene            17084..18823
                     /locus_tag="A1O50_RS09345"
                     /old_locus_tag="ERS409084_01824"
     CDS             17084..18823
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /locus_tag="A1O50_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01824"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_000699969.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.4e-38, bitscore:
                     125.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSESF
                     SESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDIVN
                     SESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGGESY
                     KLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIISDIQD
                     RLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDGNDIIN
                     LSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSNQSDLLK
                     LISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPAGSTLSLS
                     ELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYKLKDQPYNY
                     MFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNVNLIELEERI
                     QTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLFISMVNILWAK
                     KSK"
     gene            18874..19641
                     /locus_tag="A1O50_RS09350"
                     /old_locus_tag="ERS409084_01825"
     CDS             18874..19641
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /locus_tag="A1O50_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01825"
                     /product="DUF1430 domain-containing protein"
                     /protein_id="WP_061751192.1"
                     /transl_table=11
                     /translation="MSQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQDE
                     RQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQNY
                     VLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIATSIL
                     LFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVEIGVA
                     FLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            19643..20275
                     /locus_tag="A1O50_RS09355"
                     /old_locus_tag="ERS409084_01826"
     CDS             19643..20275
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /locus_tag="A1O50_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01826"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000571415.1"
                     /transl_table=11
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLMN
                     MIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIGQK
                     LSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADEPTA
                     SIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(21203..21616)
                     /gene="ndk"
                     /locus_tag="A1O50_RS09365"
                     /old_locus_tag="ERS409084_01829"
     CDS             complement(21203..21616)
                     /EC_number="2.7.4.6"
                     /GO_function="GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ndk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /locus_tag="A1O50_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01829"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_000438285.1"
                     /transl_table=11
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEEL
                     IDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRG
                     DFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     misc_feature    complement(21601..21614)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.04"
                     /tool="antismash"
     misc_feature    complement(21901..21912)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.71"
                     /tool="antismash"
     misc_feature    complement(22716..22731)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(22772..22784)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
ORIGIN
        1 gatatggata agggtcaacg tggtctgagt ggttgtttgg ttggttattc gtgcaatact
       61 cgtgcgtttt aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat
      121 ctgctagatt gcgtaagagt tcgatataaa ggcggtagtc cgtcatgaac tcttctttgg
      181 ttgaatggct ttcaataagt tcaaccgctg cataggtctc agcattccaa ccgcccccaa
      241 cgtcccaggc accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt
      301 gcgagaaaaa acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg
      361 ttgaatgcgg attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt
      421 gaggcaaatc tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta
      481 aaacaactca ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa
      541 gacaatctta gtcacgatta ggcttgtaga tagaacctca aaacgcacta ttttgacact
      601 gtaaatagga ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt
      661 ttcaaaagta tatttttaca gtctctatat gtccttttca taaatactat actttattat
      721 atcatataaa agaagtcaaa agtctgttaa actattttca acaccaaact aaagacgaga
      781 acacaagttt tttcgatttt cactagagga aatggatttt attcagtaaa tccaactagg
      841 attgcacttt ggtttccaag attgccttgc cttcttttat caagggatga cggaataatg
      901 agaagtacag ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct
      961 tatatcctgc ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa
     1021 agctagaaac tagaggaagg atcttttgcc ccaagccctg caagcaattg cgataaatca
     1081 acaagaggct caaaatggga taaaaggctg aactgatttg cagatagaga cttccatttt
     1141 ctatcaagta accatctgtc gaactagcca agaaggaaac caaggctgga ctggcaaaaa
     1201 agaggaaaat acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaaaac
     1261 cttgagcaat gcggtcaggt cgcttagctc ctagactctg agaagcaaag gtcgtcattg
     1321 atgcagaaat agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct
     1381 gagcactaat aatcactgca ccaaatgtat taacagaaga ctgtaaaatc acactgccga
     1441 tagatacaat tgaactcatc aagcccatag ccaaaccttg ctccaagaga tccgcgtaca
     1501 agcttttgtc ccatttgaaa tgtttaaact gtggcaagag ttctggcaca cttttacgaa
     1561 tataataaaa gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg
     1621 attgaactcc cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg
     1681 cagagaaaat cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg
     1741 caaaaagatt ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat
     1801 aagattgagg aagaatttct gcaggagtat ctaagtattg caagagatga tacaagccaa
     1861 gaaagcccag caacataact agaatgctca aaagagcacc taaaatccag gtggctgcta
     1921 ctgcttcctt gattttagtg aaattccgag ccccataata acgagcaatg acaatcccca
     1981 tgccattgcc aacaccaagt gtaaaaccta caatcaggtc aaaaatcgct gtcgtcgctc
     2041 ctattgcagc caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt
     2101 tatagagctg ttgaaaaata tttgatagca agattgggaa ggcgaagctt aagagcgagg
     2161 gaagaatcgg accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc
     2221 agcttcctag aggagcgaca agaaacagca aactatatat agcggaatga aataaggaca
     2281 gtcaaatcga tttttaacaa tgttttagaa gtagatgtgt actattctag tttcgatcta
     2341 ttatagttgg ttgagtttgg aatagtacgc tgtagctgct aaaacatttc tagaaattaa
     2401 tttgactttc ctaataaagt tgttcatatc ttatttcaag ctactatata taatctaaaa
     2461 acttgaatca aaaatcgaaa aagtagcgga tttctccact gctttaacag cttattcttc
     2521 aatttcgatt tcaagttcat cgcctaagtc aagcgtaact tcttcattca ctgcttcttc
     2581 tttctttggc tcatcttttt tgttttcagt atcttgttct gaaacttctt ctccatcaat
     2641 caagccaaat ttagaacgga cttgcttatc aatttcatca aagatttctg ggtgctctgc
     2701 caagtatttc ttagcattct cagaaccttg cccaattttt tcatctttgt aagaatacca
     2761 agcccctgct tttttgataa tatccaaatc gcttgcaatc ttcaaaagct caccagtctt
     2821 agaaattcct tctccgtaca taatttcaac tacggcttcc ttaaacggtg gagctacctt
     2881 attttttaca accttaatct tagtttcttt accgacattg gtttcttttt gatcaccagt
     2941 tcccttaatt tgtgtattac cacgaacatc caagcggact gaagcataga atttcaaagc
     3001 acgtccgccc ggtgttgttt ctggatttcc aaacatcact ccaacttttt cacgcaattg
     3061 gttgataaaa atggcaattg ttttggtttt attgatagag gcgccaagtt tacgcatggc
     3121 ctggctcatc atacgagcct gcaaaccaac atggctatct ccgatatctc catcaatttc
     3181 cgcacgagga acaagggcag caactgagtc gactacgaca agatcaactg cacctgagtc
     3241 aatcaatttt cccgcaatct caagaccttg ctctcctgag tctggttgag acaagagcaa
     3301 ttcgtcaata ttgacaccaa gggccgcagc ataagctgga tcaagggcat gttccgcatc
     3361 gataaaggca gcaatcccac cttctttttg cgcttgtgca actgcatgaa gggcaaccgt
     3421 tgtcttacca gatgactctg ggccatagat ttcgatgata cgtcccttag gataaccacc
     3481 tgagccaagg gcaatgtcaa gagctaaaga acctgagctc atcacttgca ccttttgctc
     3541 cgcacgttca cccaaacgca tgattgatcc tttaccaaag tctttctcaa tcaatttaag
     3601 agcgtcattc aaggcctttt cacgttctgc tccaaatttt tttgaaattt cttctaattt
     3661 ttttggtttt ttcgccattc tattctccta cattctaatg atcctcagac ctatctacta
     3721 ttatatcaaa agttagtcac ttaataaagc cttgcgaact aggttaaagg catgcataac
     3781 cgcaatgtga cgtacatctg ctcggcttct gcctccaata ttaaccttga taacctcagt
     3841 tccttgatct tgcgccaagc ctatgaagac tgtcccaact gggtgtcctt ctaggctatc
     3901 tggtcctgcc actccagtca aactaattcc aaaatcagac tgggtcttgc ttcgtgcctg
     3961 ctcagccatc ttctgagctg taaattcaga caccacacca tgttcttcca aattcttggc
     4021 aggaatatcc aacatccttg atttttcctc caagctatag gtcacaaaac caccctcaaa
     4081 tatacttgaa actccagaaa aattcgccac ggtagcttgg aaaagacctg ccgtcaaact
     4141 ctctgcagcc gcgatggttt tcccttgcct tttcagttct tctaccacaa tgctggctaa
     4201 actagtttct tccccataac catagcaaaa gtctcgtaaa gaaattcctt cgaaagtctg
     4261 gcagtccaag atttgatttt ccaagatatc cagcgcttga ttcgcctctt cttgactgct
     4321 agcctttgtt gacagacgta gagtgacttc tcctgtcttg gcataagggg ccaaggtagg
     4381 atcgatctga ttatcaatta aatcagccaa aatcgtaacc aactggctct cgccaatccc
     4441 aaagaaacga agaactcggg aatacagctt gttccctgtc atcaacttgg gtagaagttg
     4501 gtttaagacc atgggtttca attcacttgg cggacctgga aggacgacat aggtcactcc
     4561 gtctacttct aattttcctc caacagccag tcctgtttcg tttggcagtg gaatcgctcc
     4621 ttctacaatt tgagcttgtc tttcgttatt cggtgttcgg gcatagtctg gtcgcagggc
     4681 aaaaaagata tccaacttct cctgagcctg aggatcaaag actaatgctt tccctaaaaa
     4741 tttagctagg gtttgtttgg ttaggtcgtc ctcagttggc cccaaaccgc ctgtcaaaat
     4801 caccagactg ctacgttgac tggcaatctc aagcaaagac aagagacgaa cttcattgtc
     4861 tcctacagcc gtctgaaaat atacatctac cccaatctca gctagttttt ccgacaaaaa
     4921 ctgggcattg gtgttgacaa tctgtcctgt caaaatctct gttccaacag caatgatttc
     4981 tgctttcatg tttcctccta cctatctatt cgtatttttt tgaaaaaatc gcaggaattt
     5041 tcctacgatt gattttttta tttgtatcaa aagttaatta tcttcatcac caacaggtgc
     5101 tctgccaaat aaatcttcaa ataaaaccgc attggtttca agctgagtaa cttcttcttg
     5161 tcccaaagaa cgtcggagta tattttgcat ttccaacata tgtgctctcg aaacaatctg
     5221 gtaagaaaca ccttgaagta tctctccttc accctgcaac tgctgagttt caatggtttt
     5281 aaatgaatct ttatagccta gcaagttagg gatacttttt gcagacaaat caatattggt
     5341 ctgcatattg tcactcaaag cttttagaat ctcttgataa tgaccaacgc tatttaaact
     5401 gagagctttt tccatgactt tttgaataac ttcacgttga cgtttttgac gaccataatc
     5461 cccctcagga tcttggtaac gcattcgtgc atagactagg gcttcttctc ccccaatatg
     5521 ttgctcccca acaccgatag aaatagtatt aaattcttct tggtcactga tagaaattgg
     5581 gaaacctagg atattattga ctgtaatacc tcctactgca tccactagtt tttgcaaccc
     5641 tctcatattg accatcacat agcgatcaat atggatattc atcatttttt gaatggtttc
     5701 tatagcaagc tctgctccac catctgcata tgctgagttc agtttcgctt catgagcctg
     5761 accattccct gattcaatgc gcgtcagaat atcccgctct aaactcatca ttgttgtttt
     5821 tttcgtttta ggattcactg tcatcaagat catgctatca cttctaccga cccaagtttc
     5881 agttcgttca gcatttccgg tgtccactcc cattaacaga atggttagag gttcagtcgc
     5941 ttcaataacc ttggtttctt cgccgatttt tttataggtt ttagctaagg tttctgtccc
     6001 ttgttgataa atagtataag caaaaacacc tactcctact acagttacag aaagtaaagc
     6061 tagcaccatt ccaataattt ttttaaccat atttctacta atctatcagt ttacccatca
     6121 agtaaacatc gataaatttc ccttcttcta tatatgcccc acgctcttgg ctaccttcaa
     6181 tgacaaagcc atgcttttga taaagatgga ctgctgcttg attacgagtt tggacagtca
     6241 gttggagacg acgcagaatg ccacttgctt gtgcccactc tatcgcttct tctagcaaca
     6301 aacttcccaa gccattattc caatatcttt ttccaatcac aatgaagaga tctccaatat
     6361 gacggactct cttacgctgg tcagctgtaa tatttacaat accagcaatt ttgccattta
     6421 agaatgcaag taaggttatc tgattgtccg aactagcttg cttgttgagg aatatttcca
     6481 tctcctcact agtcaagaga ataccatctc cgtctaggct ggtaaagtct gtctccaaac
     6541 tcacacgatt taaaaaggcc actaattcag ctgcatcttt gggctctgct tccctaatga
     6601 gcaattcata ctccatattg aagctcctct aacaatttct cagcacgcaa accctttgcc
     6661 tgaaaattta aacggcgtcc atctgcttct tttagaattt ccaattctaa ataagcatct
     6721 ggcaaggcat ctcctaagag atttccccac tcaataacag tcacgccgcc accaaagata
     6781 aactcatcca agtcgataga atcagcatct ccttcaatac gataaacatc taggtgataa
     6841 agtggaagtc gaccttcata ctctctcacg atagtatagg taggactttt aatcatttga
     6901 gaaatctgta atccttttgc aagtccttta gtaaaggtcg ttttacctgc acccagttct
     6961 ccaattaaga ttaaaacatc attctttgct aatagatggc ccaaacgctc ccctaaggct
     7021 tgcaactctt cttcattttt tgtgtacata ctcttattat accaaaaact tttcttttgt
     7081 gtctattttc ctactaaact tatcatcata acatccataa aaaacaggct ttctctaaaa
     7141 gaaaatgagc gtaacaatga ccaatacaag atctcggaaa atatgaccat aaaaggaaac
     7201 ttccttctta accgaatttg ggacaagata ggctgcaaaa aacaagccca gtccagtata
     7261 aatcagaagt gagacaatgg tcattggatt tcttaagaaa agaagtgttg ctaaaatagt
     7321 caccaacact gtcttttttc tgtctagcat agcaagaaaa tcgcgcacgt attttttcaa
     7381 gggtaaaaaa atcagcaaat ctagcccaaa taggaaaaag aaggatggca ataaaaagtc
     7441 aactaattct tgctgcagcg tatttttgat gaacaagtta tctgacaaaa caagaacagc
     7501 tcctaacaaa ttaattaaga gtaacatact gtaaaaaagc ttcaccgact tcttactggc
     7561 taggacacta tggacttctt gcttacgggt ataaagataa tttactccag cacagattcc
     7621 tgaaacgaaa accatgcttc cgatgaaaaa agctgtactt tgtttaaagg acaagatgca
     7681 ttccttccat aggaaacagc tactcaaact gatttgaatt aaagctaaca aaaataagat
     7741 tctcattgat ttcatcttct ctctcccttc ctaccaatca ttatactagg agaaaagaga
     7801 gaactgtttc taatcttctc aaatgtctct ttaagacgct aaacaaacac tagagactaa
     7861 tactcaatga aaatcaaaga gcaaactagg tagctagcca caggttgctc aaaacactgt
     7921 tttgagattg cagatagagc tgacgtggtt tgaagagatt ttcgaagaat ataaatttga
     7981 aatcatgaaa atccgtcaaa cgggtggttg ttttgtctcg cacctcacgg agcgagacgg
     8041 actcagagtc acataattat aaggctgata gtattaatct aactatcagc cttacaggtt
     8101 atttaacgtt tcagaaaaac tataatgtca agattaacta aacagtatct agttccttca
     8161 aataattttc tatcttcatc aacattaaag gattgttata aatcttacat aactctcttg
     8221 cttctatata ataatttttg acttgttctc tgtctagaaa tttggctcca gcatttccta
     8281 caagaataag tagaggagcc aattggtagc ttgtctgtct ttgtttacag agttcaatcg
     8341 tttcaagagc ttcttggatg gcttcattat atttttcctt tgatactagg tagtgagcgt
     8401 agttgtaacg aactctgatg tagccaaata aaaactcttg atggtccaaa ttttttgtct
     8461 gatacaactc tattaaatga gagtagtttg cctcatattc ttgttcacga cccactaagg
     8521 aatagaaatt agatagagta ttcaaggcct ttaaataaat cagagtattt gaagagactt
     8581 ttaataatat attttccaat gacgaaattg cctcacactt actgtcatat tgatagaagt
     8641 caattataga tttaatccat tcaaggtaag ttcggtcttc taatgttaga aaagtgcttc
     8701 gttctacctc tattttataa agatattcta aatcgtcata atttctgtca tctaataggc
     8761 gagcagatag atgtttgaaa ttagagaggt tagacttaac ttcgatttgt tcattgaaaa
     8821 agtaatccaa agggacttca agtcgttgag agagtttgaa taacaagtct gcggagggaa
     8881 taaaatgacc tctttcaatt ttactaatct ggctttgttc acaaattcct tctgcaagag
     8941 tttgttggga gagtctcaac tcttttcttt tcaatctgaa tttctctgcg agtgtattca
     9001 ttaaagataa taaaccttcc tatttgctta atttcattat aaagttttta gttcaaaata
     9061 gcaagttaaa ggaataaata attctttatg gtaataaaca aaaaaaaaag ttaaaaatta
     9121 cataaaaata cttgactaaa taaaatatat ctgttagaat aaaaacaagg aaaaagaaag
     9181 gggtttcatt gcatgagaaa aaaacgtgga attaaaaaat tagttacatt tgcattgcta
     9241 ggtgttttta tgtttagtaa tacaattcct taccaacagt ttattcagaa gaataaacaa
     9301 ttggagattc gagtgcaatc gcaaaagaag tccaatggtc ttgatgttgg gaaggcggat
     9361 taaaacccga tattttgcac gagaatgaga gaattataat ttatctgaaa aaacgaaaaa
     9421 tatagagcaa cttatttaac tttttataag gaggagttat tacttatgac caactttaat
     9481 tcaaacgaaa aattttgtgg aaaaagttta aaatcattgt ctgctgatga aatgagttta
     9541 atttatggtg catctgatgg tgcagagcca cgttggacgc ctactcctat tattttgaaa
     9601 tcagctgcag ctagctcgaa agtatgcatt agtgcagctg tttctggtat tggggggcta
     9661 gttagctaca ataatgattg tttggggtaa attaaaatga aaaatgattt tgtaatcgga
     9721 aagagtttga aagaattatc tcttgaagaa atgcaattgg tttatggtgg cacagatggt
     9781 gctgacccta gatcaacaat tatatgttct gctacattaa gttttattgc atcatatttg
     9841 gggtcagctc agactcgttg tggcaaagac aacaagaaaa aataaaatat tcaattttaa
     9901 aaataaaagt tgctctttat tttcctctct cgtaactaat aattttgaga gaggtttttt
     9961 tttaaaacaa tagtaagtcg tataggtttg aggtaagtaa atgaaatata aaattaaaaa
    10021 tgtgcataaa acattgttta ttaaggaaag atatcaaata ttatctgaac gaaatgataa
    10081 ttccttaaat aacttttcat taaataattg gcgttctaca atgtcaatta tttctgaaaa
    10141 aacttttgaa gaaatgttga aattaaataa ttacaataaa aaaatatttt ctaacactgt
    10201 gaactatgat tataccgagg aacagataag actatattca gaatatgcca aaaattcgga
    10261 atggtataaa tttgcggagg gttcatttga aatatttaga aaacatcccc aaagaattaa
    10321 ttttaagaaa gatttttcta gaattttgga accctttatt attaatttgc ttaaattaat
    10381 caataattat ctagagaata aagaatacga gtggattgac aagaatggaa atattttttc
    10441 ctctctagta ttttatttag aagatttaat ctatccttgg attgttaaac ctttggtttt
    10501 agagataaat tcattgcgtg aaaaaggttt acttgaaggg gaatcggagc agcaacggta
    10561 caaatatttt ataacattgt ttgacaagga agagaatata ttaaattttt ataacaaata
    10621 tcccgtttta ctgaggcaaa tatcggagtc ttgtcttcgg ttctatactt attttataga
    10681 aattttatca aatttagaaa atgattttag tgtgctagaa gaagaattag ggctaagggg
    10741 gaaattaaat gatataaaat ttggaaaggg tgatacacac agccaaggaa aaactgtttt
    10801 gatactcttc tttgatgacg cgaaaattgt ttacaagcct aaaaatttaa taatcaataa
    10861 ctcactaaat actattgctg agtatatccg aaaggttgat gaaaaaatta ggataagaat
    10921 acctcgaact attgcttatt cggatcacag ctatgaagaa tttattgatt atctacctct
    10981 agagcaaaag aaaaaattac ctgaatatta ttataatttt ggtgtgcttt tagcatttat
    11041 atatttattt aatgggagtg atatacattt tgaaaattta atttcctatg gagatatgcc
    11101 tgtaataata gactttgaaa caatgttaca gcaacctcta tttgatgata aaactggtca
    11161 gagtttgctg gataccctgt ttcacagggt gactcgaact ttgcttcttc caacagaggg
    11221 agtaaaaagg gaggatggtc ttgatgttga gatgagtgct cttacaggaa attttaagaa
    11281 ggatgctttt aatggtcaag ttttaattaa tttaaatact gataaggtaa agtttgatat
    11341 tgggaaaatt gattttgaag gtgggaaaaa cctgcctgtt cgggatggtg atatagaatt
    11401 tgataagtat ataaaagatt tcaaaaaagg ttttagggat ttttatctga tatttgaaga
    11461 gttaaataaa acagaagaat ttaaaatgct attaaaagca aacttgtatg gtttaaagac
    11521 aagggtactt tttagagaca caaatagcta tgcttcagta ctatcttttt tatatcatcc
    11581 tgatttttat gaagaaatgt tagatagaga aaaagcattg gaaaatctct ggagcaataa
    11641 gttttctaat caaggtattg tagcaagcga atgtgaacaa atgaggttat tagatattcc
    11701 gattttttat acagatacaa atatcaatga aatctacgat gattttggaa atcattttat
    11761 ttccctacat caattttctg gatatgacta ttttatgaaa tatttaccta ataataattt
    11821 ggaaaattta gaaaagcaac ttgatatcat tgaaatttat tttccaagct ttgatcagcg
    11881 aaaaaaagga tataaattaa acttatctaa tagaaaaaaa ctcccaaatg aaagtttagt
    11941 tactattctg cataatgaag tagaaaatat tgcagactct ttggttatta ataatattta
    12001 tgacgaatat ccaatttgga gtatacctgt taattttaaa ggttctaaat ggtgtcttga
    12061 acaaacgggt aatgatatgt ataggggtag agctggaata ttactgttta tgtactatgt
    12121 aaaattattg aaagataaat catcatatac tcaactgtac aataaaatgt tatctgcaat
    12181 tccgccatct gtttctttat ctaagaccac atttggttta actggggata taggatattt
    12241 cattgttcta tccattatag aggattacga tacaaatact ctcgcatgct taaattatat
    12301 aaagagtgtt ttaactgagc ttgaaaagac tgattttgca agtgtttcaa acaagtctga
    12361 ctatattaat ggtcttctac ctttaattaa tacactggta agatattata ggagaggaat
    12421 agagaaggaa cgtgttctaa ggctagtatt aagtttaggt gatacgctat ataatgatgt
    12481 aagcgagaga gataatagta attttggata tagttttggc catggactat caggtgtaat
    12541 ttttacatta aaaaatattt ataaagtgac aagacttaaa aaatataaag aattaatttt
    12601 acaactagtt cctagggaga aaatcaaaat tcattctttg aagtggtgta gtggagaatt
    12661 tgggacatta gttaatcatc cccaaagtgt tccagaggga attgtagcta gtttagataa
    12721 tgatacattt tgccatggaa gtatggccat aataaatttt tacatcgact acatgaaaga
    12781 aatggatact agtatggaat tggagtcttt attgtgtagt gttgtaatga ataaatcaaa
    12841 agaaggagag tatcgtatcg tccaaacaag caatttccca gatttttctt tgtatacagg
    12901 tgtgactggt attgcttata cttttttaag gtatatcgca ctgaatcaga atgacaaaaa
    12961 gatagttatc ccctcattac ttgaaatcta gcttaattta tagttttgtt tctaaaatag
    13021 aggtgtccac tcattaagca atataaaaat accaagattg actagtttaa tatgtaattc
    13081 tataaaatat ttttaatagt gtagcttttc gttgagataa taatataata aagaaaggtt
    13141 ctattctaat tgctaaacgg cttgaggtat atgctactgt tatagaaatg attttaaact
    13201 aaaatcaaaa ttactccaaa aatagtattg attttggttt aatacaaaac atatgtaata
    13261 atgtgagtca acaaaagtct gtttttgtac catactatct tgaaaaatct actaaattca
    13321 aattgagagg atgaattaaa atgaataaaa tatttatata tgcaggagtg cgaaatcata
    13381 actctaagac tttagagtat actaagagac tttcaagtat catttctagt agaaataatg
    13441 ttgatatatc tttcaggaca cctttcaatt cagagctaga aatatctaat tctgattcag
    13501 aagagttgtt taagaaagga attgataggc aaagtaatgc tgatgatgga ggtgttataa
    13561 aaaaagagtt attagagtct gatattataa ttatctcttc tcctgtatat ttacaaaacg
    13621 tatctgtgga cacaaaaaac tttattgaaa ggattggggg gtggagccat ctttttcgat
    13681 tagctggaaa gtttgttgta acattagatg ttgctgagag taacggctct gataatgtgt
    13741 cagaatatct tagagatata ttttcatata tgggaggaca gatattacac caagtttcaa
    13801 ttaccaattc actcaaagat attgcagagg ctcagttgat ggaggcaact tataaaattg
    13861 aagatgtact tgaagggaaa attaagtaca aaacaacgga ttatcaagaa agagcttacc
    13921 agacattaaa attaatttta gaaaattatg attccgaaca ttttgagaag atgtattggg
    13981 agaaaaaacg cctttttgaa gctaatagtt tagaggaatg gtattatgtt gaaaatatta
    14041 aataactctg tcatatattt atgtttgatt ccgttattgt tcctattatt gataattttt
    14101 ccaaatgatt cattaatcta ttattttcga ttgattttaa tttcgttaat atcaattaca
    14161 ttacatgaac taggtcattt tttagtggga agatgtttat cttataaact agagatgctt
    14221 gctactccct ttttcttcta tttcagaaaa aaaatatatt tcaaatttcc agtgttatta
    14281 gcattcggtt attgtcaaat gagtaataga aacattacta atgaaaaaaa tagtgatagg
    14341 aatttggtgt tctacttctt tgggggaggt ggagctaacc taattgtcgc aatattagca
    14401 cttttgggat ttgtgccgta cgcatcagaa ttttttattt tgaatataat tctttttcta
    14461 gttacggtat gtttaccaat tgatggaaca gatggcaatg ctattagaga gatagttttg
    14521 tattcaaaag attcaaaaac atatcagaga ttctttgcga acagtctcta taataatcct
    14581 tatataacaa tcgacgattt tgcaaaatta acctctaaag aaaaatcttt tttttcaaaa
    14641 tttgaaaaat gtttgataaa cctttacttt gaagtgaaag gtgaagggtc agcatttaca
    14701 attgctaatc atgaagtttt tgattcaaat attcaggaaa atattatcca tgagtactat
    14761 aaattactac ataaatcttc tgattggatt attccacaga acttatcttt agaagaagtt
    14821 gtttttacct tgtcaaacta tatttactcg aaaaataata aatatttaga aaagattaag
    14881 tatctaaaga aattagtaga ttttagacaa gaagaaatta tcgactttat tttgaacaag
    14941 gaggaagtat tgtgaaaatt ccaatgatat atcaaatgga aaattcagaa tgtggattag
    15001 catgctgtgc catgatattg aactatttta aatatgagat ttctttaaat gaactacgtg
    15061 aaatctaccc atcatccaga tctggatatt ctctcctatc tataagtaaa gttttaggag
    15121 attttaatat aagttctcat gcttttaaag cttcggtaag agatttaaaa ccgctcagtt
    15181 tcccactcat ttgcttctgg gagagttctc attttattat tcttgaaaaa attagtaaaa
    15241 acaagtttta tattttagat cctgcaaaag gcaggcagag aatgtcaata agtgaatttg
    15301 aaaggcatta ttcaaatatc attttaacat ttaaaaagtt agatagcttt atgtctcgta
    15361 aagataataa gaagtcgcct gttttaaagt atttttttaa gtataggaat aagctaggga
    15421 ttttattttt tgtaacagca ttattgtatg taatacaatc attagtacct atagctaata
    15481 gatacataat tgacacgaat ttcaaggacg attcgtattc gtctagaatg ttatttacta
    15541 tattatttat atttactgtt tcattctcac taatgtattt attaagacag atatatgttg
    15601 catccttaaa atatataatg gataaagaga ttagctatga ttttatgaaa catttgatat
    15661 atttacctta cagtttttat gaaaaacgta ctttagggga tatacttttt agagctaact
    15721 ctattgttta tataagagaa atactatcaa ataattttat agcagctata cttgatttgt
    15781 taatgattgt ggtttatgct gtggttttat ttagcttttc taagtacatg gtaatctttt
    15841 taatatcact aagtctagct ctatctattg taatgtatcc aatcataaaa atctcaaaaa
    15901 atttaattga taaaaatata aaagaaaagg ttaatgttca aaatattact tccgaagtaa
    15961 tttctaaaaa tagtgatatt aagctaactg gagaagagga attttggatt aacaaatggg
    16021 ataattttaa tacaaaacag ctcatcatag gtcgaaaact tgatatacat ttatcaattg
    16081 ttagtagtat aacgaatgtt ttacaaatta ttctccctgt tttgaccctt attgtaggtg
    16141 taaatataaa aacattcgaa caattgacgt taggacaaat tgtagcaata agtacagtct
    16201 caccatactt tatttctcct ataatttctt taagtgataa ctatatacaa ttaatgttat
    16261 taaagggata ttttttaaga atagaggatg tgtttaatac taaatccgaa ttaattccag
    16321 aaagagtcag tcaagatata aaatttgata aaaaaataga attaaaagat atttggtata
    16381 aatatggatt atttgatgat tatgttttga aaggaataaa tgttactatt aaaaaaggag
    16441 aaactgttgc tattgttgga gaatcaggtt caggtaagag tacattagct aaaattttat
    16501 taggtttatt agaacctaat attggttcaa tagaagttga tggagtagaa aaagaagaaa
    16561 ttggtcaaac attgtataga aagatttttg gagcagtgtt acaaaattca accctaagtt
    16621 atggtacctt aagagagaat ttgacatttg gacactttgt ttcagatgaa gaattaatga
    16681 caaatctaaa ttcaattggt cttagcaatg tagttaaatc tttacctctt ggattagaga
    16741 caatcatcgc tgaagaaggt aataactttt ctggagggca gcagcaaatg atacttttag
    16801 ctcgttgtct tttgtcgaaa ccttcggtag ttgttttgga cgaagcaaca agtagtttag
    16861 ataatttatc tcaacaaatt acaacttctt acttaagtga aatcggtacc actaagattt
    16921 taattgccca tcgactagat actatcaagt ctgcagataa gatcttagta atgcataatg
    16981 gtgaaattgt agagattggg acccatagag aacttcttga actaggaggc atttataagc
    17041 aattgtattc aaataattag tttttgatta aaagggtaaa tttatgaaga ttatgaaaaa
    17101 aaaatattgg actttagcga tattattctt ttgtttgttc aataattctg ttactgctca
    17161 agaaatacct aaaaatcttg atggcaatat aactcacact cagactagcg aaagtttttc
    17221 tgaatctgat gaaaaacagg ttgactattc taataaaaat caagaagaag tagaccaaaa
    17281 taaatttcgt attcaaatcg ataagacaga attatttgta acaacagata aacatttaga
    17341 aaaaaactgt tgtaaattgg aacttgaacc acaaataaat aacgatattg ttaactctga
    17401 aagtaataat ttactaggcg aagataattt agataataaa attaaggaaa atgtttctca
    17461 tctagataat agaggaggaa atatagagca tgacaaagat aacttagaat cgtcgattgt
    17521 aagaaaatat gaatgggata tagataaagt tactggtgga ggcgaaagtt ataaattata
    17581 ttctaaaagt aattctaaag tttcaattgc tattttagat tcaggagtcg atttacaaaa
    17641 tactggatta ctgaaaaatc tttcaaatca ctcaaaaaac tatgtcccca ataaaggata
    17701 tttaggaaaa gaggagggag aggaaggaat aatatcagat attcaagata gattaggtca
    17761 tggtacggct gttgtagctc aaattgtagg ggatgacaat attaatggag taaatcctca
    17821 cgttaatatt aacgtctata gaatatttgg taagtcgtca gctagtccag attggattgt
    17881 aaaagcaatt tttgatgctg tagatgatgg caatgatatt atcaatctta gtactggaca
    17941 atatttaatg attgatggag aatatgagga cggaacaaat gattttgaaa catttttgaa
    18001 gtataaaaag gctattgatt acgcgaatca aaaaggagta attatagtag ctgcattagg
    18061 gaatgactcc ctaaatgtat caaatcagtc agatttattg aaacttatta gttcacgcaa
    18121 aaaagtaaga aaaccaggat tagtagttga tgttccaagt tatttctcat ctacaatttc
    18181 ggtcggaggc atagatcgct taggtaattt atcagatttt agcaataaag gggattctga
    18241 tgcaatatat gcgcctgcag gctcaacatt atctctttca gaattaggac ttaataactt
    18301 tattaatgca gaaaaatata aagaagattg gattttttcg gcaacactag gaggatatac
    18361 gtatctttat ggaaactcat ttgctgctcc taaagtttct ggtgcgattg caatgattat
    18421 tgataaatac aaattaaaag atcagcccta taattatatg tttgtaaaaa aaattctgga
    18481 agaaacatta ccagtaaaaa atggtataaa agtgttaaat ataccaaacg tattgagata
    18541 tgatttgaat atgttacaat tagaatataa aaatgaacaa agttgggata gtttcataga
    18601 taatgttaat ttaattgagt tggaagagag aattcaaact actattggaa ttaaacaaat
    18661 aaacacacac aatattatta ctattgcccg agaagggtac tctcaaaatt atttacctaa
    18721 cacttcagaa aatacatata attcattaca agtcagttta gttggagtat tactactttt
    18781 tataagtatg gtaaatattt tatgggctaa aaaaagtaaa tgaaaataaa atttggagcc
    18841 ctctgaaaaa gtaagtccta cagttcaact aaaatgagtc aaaagatgaa tcaccttaat
    18901 gtaggggagt ttgtcttatt gctgcctgaa cacctccgtt cagaggaaga acattataaa
    18961 tctgtttttg aagacgactt aaccagtcgc atgtctagtc aagatgaacg acagcaaatg
    19021 actgctacgg taggttattt agaatcaggt caggatcgtt ttgtgtataa tacgacccct
    19081 atttcttacc agcagttttt gaaagatcca atcatcattg ttataacacc ccaatcaact
    19141 ggtccacagt ccattttgtt ttggatagac gcagtacaga actacgttct ctttaatcaa
    19201 ttgtctgatg cccaggagct tatccagaga caaggcattg aaaattgggt ctcagaaatg
    19261 caaacaggtt accacaacta catcacatta ttggataata tccagaggga acgttgggta
    19321 atgctagcag gagctgtgct tgggattgca acttcaatct tgttgtttaa cactatgaat
    19381 aggctctact ttgaagaatt tagacgtgcc atttttatca aacgcattgc aggtctcagg
    19441 ttcttagaaa tccatcgcac ttatctcttt gctcaactgg gtgtgttttt actgggattt
    19501 gttgcgagtg tatttcttca ggtagagata ggagttgctt tcttagtctt gttactcttt
    19561 actggtctat ctcttttaca gttacatgtc caaatgcaga aagaaaacaa gatgtccatt
    19621 cttgttttga agggaggtta atatgattga acttaaacag gtgagtaaat cttttggaga
    19681 acgagagtta ttttcgaatc tttcaatgac atttgaggct ggaaaagtct atgccttaat
    19741 tggttcaagt ggtagcggaa aaacaacctt gatgaacatg attgggaaat tagaacctta
    19801 tgatgggacg attttttacc gaggtaaaga cttggccaat tataaatcga gtgatttttt
    19861 ccgtcacgaa ttgggctacc tcttccagaa ctttggctta attgaaaacc aaagtattga
    19921 agaaaacctt aagctaggtc tcattggtca aaagttgagt cggtcggaac agcggttgag
    19981 gcagaagcag gctttagaac aggtcggcct ggcttatctt gacctagata agcgcatctt
    20041 tgagttatcg ggcggagaat cgcaacgggt tgccttggca aaaattatct taaagaatcc
    20101 accctttatt ctggcagatg agccaacagc ttcaatagac ccagcaacct ctcagttgat
    20161 tatggagatt ttgctatctc ttcgagatga taataggcta atcattatcg caacacataa
    20221 tccggcaatt tgggagatgg ctgatgaagt gttcacgatg gatcatctga aataaaaatc
    20281 cttgttttta attgcacgat gagttactga aatattatca tgaatcaaga attggagtta
    20341 atttagaatt gtactttatt aatattgagg taactttttc ttgataaagg aagaaataat
    20401 ggagaggaag ttagaatgaa aaaattcgac aattatatta ttgagaagcc ttgcgattct
    20461 aattcagata aactgcaaaa aatcttaata attgaaagtt tggtagatga tattttgcaa
    20521 ttttctctca gaatcaataa tagtgtagga gagattttcc tcctacaacc gttttaaaag
    20581 aaaactatct ttattccatg ttattttgag gaagatattg tgaaagtcaa agatgatgat
    20641 aaagttgagt ggaatttgtt agaatttcaa aaatttagag catttttggc ttagtaatct
    20701 gtgttgaagg ctcaaaacct atggtaaaaa agtagctttg aaaacgtatt gcctccaaag
    20761 atttagttaa ataatgattt aacacaaaaa gaaattattg aagttctgga aagatgttgt
    20821 ttcagtattg agaaaaggtg ggaaaaactt gcgattttca cagagaaagg aagaaaaagt
    20881 atagaaatat agtcaattga aacaagaaca ggacaaaaga accttttgtg ccatattttt
    20941 ctcctttcgc tttacaattg gcttgaacac ctttattgta tcgcgtttgg agtttttttg
    21001 gtataacctt cgacgcgcac ccgcatagcg ggtgtttttt tgtctcgcac ctaacggagc
    21061 gagacgaact aatagtcact taatcaaaaa acgcaccata tcaaaaacta aaaagtttga
    21121 tatcatgcgt catgtcttaa actaattgac tatactttct attcaaatga gcttttaacc
    21181 aattgattga gccaatccac tcttaaaacc aaagagcaat ttctcgctta gctgactctt
    21241 ctgaatctga accatgtaca acattttgga taacctcatt ttctccagca gcttttgcaa
    21301 agtcacctcg aatagtgcct ggtaaagctt cttctggacg agttgcaccc atcatggtcc
    21361 gccaagtttc gattactttg ggaccagaaa tgacacccac aagaactgga cctgaagtca
    21421 tgaattcacg aatcggtagg taaaaactct gaccaaccaa gtcctgatag tgctggtcaa
    21481 tcaactcttc tgaaacctgt gaacgaaact ccaatttttc gattgtaaat ccacgttgtt
    21541 cgatgcgctt taacacttca cccactagcc ctctttttac accatctggt ttgatgataa
    21601 agaatgtttg ttccataccc gtctcctttg tcagcttctt tcttttattt taccacattt
    21661 cgtggaaaaa tggagaaagt tttcagaaga gagaatgaga gaacccgagg gttctctcat
    21721 tctctcttat tctactgttt cttccacagt ttcaacggca gtatccacaa ctacttctgt
    21781 tgtttcttca tttccttctt cctctactgg aggattaagg tattcttctt cgttgacagc
    21841 atgtggttca aggttacggt aacgggccat accagtacca gctgggatga tcttaccgat
    21901 gataacattt tctttaagtc caaggagatg gtctttctta ccacggatag ctgcgtcagt
    21961 aaggacacga gttgtttctt ggaaggaagc tgctgacaag aaactgtttg tttcaagtga
    22021 ggctttggta attcccataa ggactgggcg acctgtcgct ggaactccac ctgcgataag
    22081 gacatctttg ttggcatctg taaagtcatt gatatccatg agggtaccca tgagaagatc
    22141 tgtatcacct ggatccatga cacggacttt acggatcatt tgacgaacca ttacctcgat
    22201 gtgtttgtca ccgatttcta ccccttggct acggtaaact ttttgtactt caccgagaag
    22261 gtacgtttca actgacaaga catcacgaac tgcaaggaga cgttttggtt ggatagaacc
    22321 ttctgtcaga gcagcaccac gcgctacttg gcccccaact tcgacacgca tacgagctgt
    22381 aaatggaacg acatattcac cttcgccagt ttcaccctta acaaagactt tcttggtacg
    22441 agttgatgca tcttcttcga tagcagtaac ttgtccttta acctctgtga taaccgcttc
    22501 ccctttagga ttacgggctt caaagatttc ttggacacga ggaagaccct gagtgatatc
    22561 ggtatttgag gcaaccccac ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc
    22621 cccgatagat tgggcagcaa ttgtaccaac tgcttcacca acttcaaccg catcaccagt
    22681 cgccaagttt ataccgtaac agtgacggca gacaccgtga cgagtgttac atgtaaatac
    22741 agaacggata gtcacttctt ccacaccagc attgacaatt tcacgcgcct tgtcttctgt
    22801 aatcaattca tttggaccaa taatcactgc accagtttct ggatgtttaa cagttttctt
    22861 agtgtaacga ccgttgagac gctcttcgag agactcgatc atctcttttc cttctgcgat
    22921 agaacggatc aagagaccac ggtcagttcc acagtcgtcc tcacggatga taacgtcttg
    22981 ggcaacgtcg a
//
