LOCUS       NZ_FDFR01000004        17347 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 2842STDY5753301, whole genome
            shotgun sequence.
ACCESSION   NZ_FDFR01000004
VERSION     NZ_FDFR01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900022985.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 02:12:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,313
            CDSs (total)                      :: 2,259
            Genes (coding)                    :: 2,086
            CDSs (with protein)               :: 2,086
            Genes (RNA)                       :: 54
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 71 of 173
            Pseudo Genes (incomplete)         :: 93 of 173
            Pseudo Genes (internal stop)      :: 58 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:29:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 17347
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FDFR01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17347
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..17347
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17347
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[6471:7347](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(6472..7347)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(<1..341)
                     /locus_tag="A1O50_RS05590"
     CDS             complement(<1..341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /locus_tag="A1O50_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="WP_061714279.1"
                     /transl_table=11
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREAL
                     ITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVIVRLEKPVTFHNMIAPDKEV
                     EVSLLFFII"
     gene            521..853
                     /locus_tag="A1O50_RS13495"
                     /old_locus_tag="ERS409084_01085"
     CDS             521..853
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1O50_RS13495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS409084_01085"
                     /product="hypothetical protein"
                     /protein_id="WP_000693379.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDKTDEVSSKHDFEVVDETDEVSS
                     KHGSEVVDETDEVSSKHGFEVVDETDEVSSKHGFEIVDETDEVSNHTYGKATLTWFEEI
                     FEEYKN"
     gene            complement(934..2757)
                     /gene="lepA"
                     /locus_tag="A1O50_RS05600"
                     /old_locus_tag="ERS409084_01086"
     CDS             complement(934..2757)
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="A1O50_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01086"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047222.1"
                     /transl_table=11
                     /translation="MNLEELKKRQRKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(2836..3564)
                     /locus_tag="A1O50_RS05605"
                     /old_locus_tag="ERS409084_01087"
     CDS             complement(2836..3564)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="A1O50_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01087"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_000133332.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            complement(3566..5233)
                     /gene="recN"
                     /locus_tag="A1O50_RS05610"
                     /old_locus_tag="ERS409084_01088"
     CDS             complement(3566..5233)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="A1O50_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01088"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923570.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(5240..5671)
                     /locus_tag="A1O50_RS05615"
                     /old_locus_tag="ERS409084_01089"
     CDS             complement(5240..5671)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="A1O50_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01089"
                     /product="arginine repressor"
                     /protein_id="WP_001034412.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(5664..6479)
                     /locus_tag="A1O50_RS05620"
                     /old_locus_tag="ERS409084_01090"
     CDS             complement(5664..6479)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="A1O50_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01090"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041073.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEAGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(6472..7347)
                     /locus_tag="A1O50_RS05625"
                     /old_locus_tag="ERS409084_01091"
     CDS             complement(6472..7347)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="A1O50_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01091"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_000743808.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.9e-57, bitscore:
                     186.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFETESIV
                     SVVESLRING"
     gene            complement(7344..7556)
                     /locus_tag="A1O50_RS05630"
                     /old_locus_tag="ERS409084_01092"
     CDS             complement(7344..7556)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="A1O50_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01092"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(7534..8874)
                     /gene="xseA"
                     /locus_tag="A1O50_RS05635"
                     /old_locus_tag="ERS409084_01093"
     CDS             complement(7534..8874)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="A1O50_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01093"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000417494.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQVTIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQWDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMATA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(9002..9640)
                     /gene="udk"
                     /locus_tag="A1O50_RS05640"
                     /old_locus_tag="ERS409084_01094"
     CDS             complement(9002..9640)
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="A1O50_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01094"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     misc_feature    9680..9694
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(9748..10050)
                     /locus_tag="A1O50_RS05645"
                     /old_locus_tag="ERS409084_01095"
     CDS             complement(9748..10050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="A1O50_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01095"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985093.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQTV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(10291..11169)
                     /gene="truB"
                     /locus_tag="A1O50_RS05650"
                     /old_locus_tag="ERS409084_01097"
     CDS             complement(10291..11169)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="A1O50_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01097"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013260.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     gene            complement(11179..12453)
                     /locus_tag="A1O50_RS05655"
                     /old_locus_tag="ERS409084_01098"
     CDS             complement(11179..12453)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="A1O50_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01098"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_050199618.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEVQD
                     LENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            complement(12549..13808)
                     /locus_tag="A1O50_RS05660"
                     /old_locus_tag="ERS409084_01099"
                     /pseudo=""
     CDS             complement(12549..13808)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="A1O50_RS05660"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01099"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            complement(13956..14753)
                     /locus_tag="A1O50_RS05665"
                     /old_locus_tag="ERS409084_01101"
     CDS             complement(13956..14753)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="A1O50_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01101"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_044812798.1"
                     /transl_table=11
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLEGIL
                     ANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     misc_feature    complement(14906..14920)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.19"
                     /tool="antismash"
     gene            complement(14997..15740)
                     /gene="srtA"
                     /locus_tag="A1O50_RS05670"
                     /old_locus_tag="ERS409084_01102"
     CDS             complement(14997..15740)
                     /codon_start=1
                     /gene="srtA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /locus_tag="A1O50_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_01102"
                     /product="sortase SrtA"
                     /protein_id="WP_044792209.1"
                     /transl_table=11
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVWN
                     TNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPELE
                     MNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNAKNG
                     MKIYLTDKNKVYTYEIREVKRVAPDRVDEVDDRDGVNEITLVTCEDLAATERIIVKGDL
                     KETKDYSQTSNEILTAFNQPYKQFY"
ORIGIN
        1 ttgatgataa agaagagcaa ggatacttct acttccttat caggagctat catattgtga
       61 aaagttactg gtttttctaa tcgaacaatc accactttct cagctagatt atgaacaata
      121 tctgtgtgag gaatcgctac atttggcaag ttctttccta gaaattccat atctaaacca
      181 gttggaaatg acttttcacg cgtgatcaag gcttcacgat aagttggagt gacaatttct
      241 cgttcttcca ataaagttgc aacctgatca aagagttgtt cttgattatc cgcttctaag
      301 caaaacacaa ggtttttgtc aaagaaataa tctaatacca taaggttttc ccttctttcc
      361 attaacttta tgccataagt ataacactat atgaaatcgt tgttaattac tttctgttct
      421 ttttttgtct cttttttata tttttgtttt gtttatagtt tgttatataa aaataaacac
      481 acaaacaaat actccaagca tttttctgtt ctaatactca atgaaaatca aagagcaaac
      541 taggaagcta gccgcaggtt actcaaaaca cagttttgag gttgtagata agactgacga
      601 agtcagctca aaacatgatt ttgaggttgt agatgaaact gacgaagtca gctcaaaaca
      661 tggttctgag gttgtagatg aaactgacga agtcagctca aaacatggtt ttgaggttgt
      721 agatgaaact gacgaagtca gctcaaaaca tggttttgag attgtagatg aaactgacga
      781 agtcagtaac catacatacg gtaaggcgac gctgacgtgg tttgaagaga ttttcgaaga
      841 gtataaaaac taaaaaagca gaccatctaa gcctgcttta ctattgattc ttatataaat
      901 ttcctgtgaa caaggaaagg catttctgat aacttattct tcatccatac tcaagacgct
      961 gaggaaggct tcttgcggaa cttcaactga tccgatggat ttcatgcgtt tcttaccagc
     1021 tttttgtttt tcaaggagtt tacgcttacg agaaacgtca ccaccataac atttagcaag
     1081 tacgttctta cgaagggcct tgatatcagt acgagcgaca atcttgtgtc caatagccgc
     1141 ttggattgga acttcaaatt gttggcgagg gatgattttc ttgagtttat caacgatgag
     1201 tttcccacgt tcgtaggcaa agtccttgtg aacgataaag ctgagggcat ccaccttatc
     1261 tccattgaga aggatatcca ttttcaccag cttagatggg cgatattctg acaattcgta
     1321 gtcaaagctt gcataaccac gtgtcgaaga cttaagttta tcaaagaagt caaagacaat
     1381 ttcagcaaga ggaatttgat agataacatt gacacggtta tcatcaatat agtccatagt
     1441 cacaaagtcc ccacgcttac gctgagctag ctccattact gctccgacga actcctgtgg
     1501 taccatgatt tgcgccttga cataaggctc ttcaatggtc gcaatcttag ttgggtctgg
     1561 aaactcagat gggttagaca catccataga ctcaccgtcg gtcaaattaa ctttgtaaat
     1621 aacagacgga gctgtcatga tgaggtcaat attgaactca cgctctaaac gttcctggat
     1681 aacatccata tggagaagtc caagaaatcc acaacggaaa ccaaatccaa gtgcctgaga
     1741 tgtttctggt tcaaactgaa gactagcatc attcagttgc aatttttcaa gcgcttcacg
     1801 caggtcattg tatttgtttg attcgattgg gtagagaccc gcaaagacca taggattcat
     1861 ctgcttataa ccatgtaatg gttctgccgc aggattggtt gccaaggtaa cggtatcacc
     1921 cacacgagta tcctgaaccg tcttgataga cgccgcaatg taaccaacat caccagtcgc
     1981 aaggaaatca cgaccaaccg cttttggtgt aaaaataccg acttcggcca catcaaaggt
     2041 cttactattg ctcatgagct gaatcttatc accaggtttg accactccgt ccatgacacg
     2101 cacttggagg ataaccccac ggtaagcatc gtaaacagag tcgaaaatca aggccttaag
     2161 tggcgccgtc acatcacccg ttggtgctgg tactttttct acaatttgct cgaggatttc
     2221 ttcaatccca ataccagcct tggcagaagc caaaactgct tcactggcat ccaaaccaat
     2281 cacatcttca atctctgtac gcacgcgctc cggatctgca gccggcaggt caattttatt
     2341 aatgataggc atgatttcca aatcattatc caaagccaga taaacgttgg caagagtttg
     2401 agcctcaatt ccttgagccg catcgaccac caaaatagca ccctcacagg cagctagcga
     2461 acgtgaaact tcataggtaa agtcaacgtg ccctggtgtg tcaatcaagt ggaaaatata
     2521 agtttcccca tcttttgcag tgtaattcaa ctcgatggca ttcaacttaa tagtaattcc
     2581 acgttcccgc tctagatcca tgctatccaa aagctgggcc tgcatttcac gacttgaaac
     2641 cgtctctgtt ttttccaaaa tgcggtctgc tagagttgat ttcccgtggt caatatgggc
     2701 gataatagag aagttacgga tcttcctctg tcgttttttc aattcttcta agttcatgat
     2761 tctcttcctt tcagggtatc tatttattat aaattgtttt tgatattttg acaagaccat
     2821 accctgctag gagtactaat cttcagcgac aaagccgtca ttttcgataa agtggtgttc
     2881 tgtcattcct tggtctgtaa agacaatccc gtgaaggaca ccaccataaa cagctcctcc
     2941 atccattcca atcttgccat cttctgtagt ccaaagctca gatgtaccgc gttcttgctg
     3001 taacaaacca tagaccggtg tatgaccgaa gacaatggtt tttccagtat gattttcagc
     3061 tccgtggaat ggttttctaa gccatacttt tttataatct gttgtttcat gccagtcgtc
     3121 caaagtcaaa tcaatacctg cgtgaacaaa tatatacttg tctgtctcta ctacaaatgg
     3181 catttgacga atgaattcga ccaagtctga cgcttcagcg gcaacccgct tggcatcttc
     3241 tactccatca actggtgcat ccaagggacg acctaggata gagttaatgg ttgtatctcc
     3301 accattgcga cgataatggt cataactttc ttctgggtca tctagccaag tcaaaaacat
     3361 atactcgtgg tttccggaca aacagatagc cccttgattg tccaccaagt ccttgaccat
     3421 ttcaagaaca cggtgactat cctcacctct gtcaatcaaa tcacctagaa agagcaactg
     3481 gggctgacca tcccaggttt tgagaaggtc ttccagcatc ccagcttttc cgtgaacatc
     3541 tccaattaca taataatctg tcatcttatt tctccctgtt tctcaacaat tctctggctt
     3601 gcgtcagggc tgcttctgtc acatcatcac ctgccaacat cttggcaact tcctccactc
     3661 gctcttcgac cgtcaagaga cgaacagtcg aaaccgttga atggtcatta ctaatcttct
     3721 caataaagaa ttgataatct gcaatcgcaa ttacttgtgg caaatgggag atagccaaaa
     3781 cctgaccatg ctgaccaatt ttatgaattt tctgagcaat agcttgagca acacgacctg
     3841 aaactcccgt atccacctca tcaaagacaa tgctagtctt gccttcttta cgtgaaaagg
     3901 cagacttaat ggctaacatg agacgagata attcccctcc agaagcaacc ttaaccaagg
     3961 gtttaaagtc ttctccaggg ttggttgaaa tataaaactc aaccatttca tttccctcac
     4021 gactgaattt tcccttacta aaacgaacct gaaactgggc tttttccata taaagatctt
     4081 gcagttcttg tttaatctca gcttcgagtt gctgagccaa attatgacga gcagaagcaa
     4141 gttgacctgc caaattgaca agattgactt ccaacttctt aagctctgct tccatgtcct
     4201 cagacgaaag attattgcct gtcaagagat tgtattcttc cgtaatcttg gcaaaataaa
     4261 gcaaaacatc atcaacagtc ccaccatact tacgagtaat agtatgaagg aggtccaaac
     4321 gattctcaac ctgcatcagg cgattgccat caaaatcaag gtcctcaatg atagcttcca
     4381 aacgtttgct aatgtcttct aaaacatagt aggtctcaga cagagagctt gaaatttcac
     4441 ggtattcagg atcatactct tcgacacttt ccatgtcatt catagctgaa cgaacattgg
     4501 ccagacttga aaaatcttca ttgtccaaca tactgtaggc attggtcagt gtatccgcaa
     4561 tatttttgtg gttgaggagt ttatctcgct cttgattgag agccaagtct tctccagcct
     4621 gcaagtttgc tgcctcaatc tctgccattt gaaattccaa catttcgata cgtgccttgt
     4681 gttcctgttg gtttttcttg acttccagaa cctgcttgcg cattttccga taggcatcaa
     4741 aactcgtttg ataggtttct ttcaagtccc aaaaagcggc atcaccaaat tcatccaaca
     4801 tctggatatg cagttgggga cgcattaact cctcatggtc atgctgacca tgaatatcta
     4861 caagatgttg cccaatagct cgcaaaacag acagattaac catctgacca tttacacggc
     4921 tgatactacg accattttgc aagatttccc gacggatgat aatttcatca cctaattcta
     4981 aaccttgctc atcaaaaatt tcctgtaaaa ggcgactatt ctcaactgag aaaagcccct
     5041 caatctctgc ctttggtgca ccatgacgaa taacatctgt cgtcgcacga gctcccaaca
     5101 tcatattcat ggcatcaatg ataatcgact tccctgcacc cgtttcacca gtcaggacag
     5161 tcatcccctt ttcaaaattg agggaaatag cctcaataat ggcaaagttt tttatcgaaa
     5221 tttcaagtaa catatagacc taccaatttt ttacttgttc aaagatttcc tctgctagac
     5281 ttccacttct ggcaatgact aaaatcgagc tatcatcagt caaacaacta aaaatcttgt
     5341 ctgcaaaagt atcgattaac tgagctttta caaaagccgt atttcctgga ataacttgga
     5401 gattgatcat cttatccatc aattcagccg attcgatatt gtcttcagcc agttgcagac
     5461 tttttacgat tgattttggt aattcgtaga cataggtgtt gtctctcaaa ggaattttga
     5521 caatacctaa ctctttgata tctcgggata ccgtcgcctg agtggcagtg atacctgctt
     5581 ctttcaaatg ttctacaatt tcttcttgcg tgccgatttg ataatctgtc accaatcttc
     5641 taattttttc aagtctttct tttttattca tttttaaatt gactatgcgc cctctctact
     5701 gcttctttaa tctcagcaag aatctgattg cttgctgact tttctttttt caaatacgct
     5761 aaaaattcaa tatttccatg tccaccttgg atgggagaaa agtccaagcc aaggactgaa
     5821 aaacctgcct ctactgccat agctgttaca gattcaagga cattctgatg aatcttagca
     5881 tctcgaataa ttccattttt cccaatctgc tcacgtcctg cctcaaactg aggtttgaca
     5941 agtgctacca cctgaccttg atcagccaag acacggtgca aggctggcaa aatcagacta
     6001 agggaaatga aactcacatc aatactggca aagctcggct cctgctcgaa atcagtcttt
     6061 tcagcatagc gaaaattgaa ctgctccatg ctgacaactc gtgggtcttg gcgtaatttc
     6121 caagccaact gattggtacc aacatcgact gcaaagacca acttggcact attctgtagc
     6181 atgacatcgg taaaacctcc agtagaggcc ccgatatcaa tcgtagtcgc gccatccacc
     6241 gacaaatcaa aaacctgcaa ggccttttcc agtttcaaac caccacggct gacatacttg
     6301 agtttctccc ccttgagttt taattcggtg tcatctggaa ttttctctcc tggcttgtca
     6361 aaccgttctc cattaaggac tgctacgact aggccagcca tcacacctcg cttggcctgc
     6421 tctctcgttt caaacaaccc ctgtttataa gctagtacat ccactctttc cttagccatt
     6481 gattctcaaa ctttctacta cacttacaat cgattctgtt tcaaagggaa gctgctgggc
     6541 aatttcttct aatttttcat tagcttgatc cagggtttgg ttacaaaagg caatggactc
     6601 ttccaagccc aacaaggcag gataggttga tttttctgcc tgcagatcct tttgaggtgt
     6661 cttaccgatt tcctcaaaac tagctgtcac atccagtaca tcatctctga cttgaaaagc
     6721 aagtccaatc aattcaccca cagttttcag cttcacctgc atttcaggtg acaattcagc
     6781 tataatagct gccgcttgga agggataggc tagtaacttc ccagtcttat tggcatgaat
     6841 agtctgaagt tcttccagag acaagtgctg gtgttcgccc tccatatcca aaacttgccc
     6901 tgccaccata cccagactac ctgaagcaag ggataagttg gcaatcaagt ccaccttgat
     6961 ctgacttggc aaatctgcct gcgcaatcaa ggcatatggg tctaagaata aggcatctcc
     7021 agccaaaatg gccatagctt caccgaattt cttgtgattg gttaaccgcc ctcttcgata
     7081 atcgtcatca tccatagcag gaaggtcatc gtgaatcaag ctccctgtat gaatcatctc
     7141 caaggcagta gctacctgcg cgtgagcagg tttgatggca acctgcaagg cttccagaac
     7201 ttctaacaag agaaaaggcc gaatacgctt gccaccagca tgaatagaat agagaacaga
     7261 ctcccgtaaa ctagaggcaa actgctggtc tccataaaaa tcttccaaag ccgactcgac
     7321 aagagctaat ttttcttgct ttttcattca aaatcacttt ctgttccgtc ttcttgcatg
     7381 acctttacca aggtcttttc agccttgtcc agcgtagctt ggagctcttt tgacaagacc
     7441 atgccctttt gaaaggcagt aatcgcatct tccagagcaa tttcaccatt ttccaaactt
     7501 tggacaatgg tttccagttc tgctagattt tcctcaaatt tcttttgttt tgacatcttt
     7561 aacctctaat tctacttgac catctcgcat caaaagcgtt acttggtctt ttttcttcaa
     7621 actctcaacc gaatctacaa cggactcttc ttttttgaca atagcataac cacgcgccac
     7681 gattcggcta gtatccaaca tgagcaaagc ttccgaaagt cgcttggcct cagcaacctt
     7741 ggcgtcataa actaacgcca tttggctacc taagagcttg tccaactgtc ctaaacggtc
     7801 ttgatagcgt tggattttgg taacaggtga taattgtact aattgatgag ttcttgcttg
     7861 aactaattgt ttgttatcag aaatccgagt tcgcaaactt tgtttcaaac gcagttgcag
     7921 ttggtccaag cgttgcaaat aaccgtcata caagcgctca ggttgtctaa agataacaga
     7981 ctgactgcat tttttcaaag cctcttgttt cttagataga acatttcgga ctgccgttgc
     8041 catccgtttt tcctgatttt gcaaatgagc taatacatcc aacttggtca caggtgttgc
     8101 cagttcagcc gccgctgttg gcgttgcagc gcgtcgatct gccacaaaat ctgccaaggt
     8161 cacatccgtc tcatgcccca cactagagat aactggcaaa cgagattcaa aaatagctcg
     8221 taccacaatt tcttcgttaa aggcccagag atcctcaata gaaccacctc cacgaccaat
     8281 aatgagcaaa tccaaatcgt cccattgatt agcacgcgca atatttctag caatttcctc
     8341 cgcagcccct tcaccttgaa ccttggtcgg ataaagaagg atgtcaacac ctgggaatcg
     8401 cctgctgacg gtcgtgataa tatctcgaat aacggctcca ctacggctgg ttactacccc
     8461 aattctctta gaaaattggg gtagagcttg cttgaagcgt tcttgaaaca ggccttcttc
     8521 tgtcaatttt ttcttaagtt gttcaaactg aatcgcaagc gccccaaccc catcaggctc
     8581 agctttttca atgatgatgg agtagctacc acttggttca tagacctgta cacgcccaat
     8641 cacattgatc ttcattcctt cttccaggtc aaaccctaat ttctgataaa tcccagacca
     8701 gatggtcact tgaataactg catggtcatc ctttagggag aaatattggt gagtaggtcg
     8761 tttacgaaag ttggaaactt gaccagttaa atagacccgt tccaagtatg ggtctttatc
     8821 gaatttcatt ttcagatact tggtcaaagt tgttaccgat aaatactttt ccatctccac
     8881 ctactattca tttacttgct ctttcatggg tattattata ccaaaaatat gcctaaaaat
     8941 ctccatttat gtaccattat gagggaaaaa tagaaaaagg aggcaaggcc tccacatgtg
     9001 attatttgct gtttcgagct tcttccaaaa tctttgcaat cttggtcgtc aacaggtcga
     9061 tagccacggt attgctaacc ccttcaggaa tgacgatatc agcataacgc ttagttgact
     9121 cgataaactg gtggtacatt ggtttgacca cacctaagta ctggttaata acgctatcaa
     9181 ggctacggcc acgctcctcc atatcacgct tgatacgacg aataatacgc acatcgtcat
     9241 ccgtatccac aaaaatcttg atatccatca aatcgcgcag acgcttgtcc tccaagacca
     9301 aaatgccctc aacgataaag acatcttgag gctcctgacg ataggtcttg ctactccgtg
     9361 tatgctctgt atagtcgtag gtagggatgt ccaccggacg ccctgccaac aattccttaa
     9421 tctgctcgat catcaagtct gtatcaaagg caaaaggatg gtcatagttg gttttgacac
     9481 gctcttcaaa ggtcaaatga gactgatcct tgtagtatga atcatgctca atcatggaaa
     9541 tcttttcatc aggaaaatgc gataaaatgg ctcttgaaac actggtttta ccaccaccag
     9601 aaccacctgt cactccaata atgattggtc tattttgcat gctatcctcc gttattttat
     9661 ccgtcgtcta ttctatcaca ttttttacaa aatttatagt ctcatcagca aaaaacacca
     9721 gagtcttccc tctgatgttc gacagtttta acgaaagccc tgtagggttt gagcaagcat
     9781 ctgcaagaaa gccagtctcc ctctttcctg gctaggagct ttggcaatcc ataaaccaaa
     9841 atcaatgaca gacttaggtg cctggtaatg atgcgtcatg aggtaaagtg acaacccttg
     9901 actcaaattg gccatgaccg tttggtattt ttcatttctg tctaaatttt gtatagcaag
     9961 acgaaacagg tgactcaact cactattttc atttatttct ttttgttgaa gaagttgctc
    10021 caccctttct cgaaactcat ttcgcatcat ggaattatca caccaaatcc tgggcctaag
    10081 ttcccaccag aacctgtaat ggactctaaa tatttatctg aaagaatttt aagttgcttc
    10141 atttcacacc tctaaatttc tatatagatt atttgagtat ctacaactcg caacaattgg
    10201 aatattataa ttcccaaaac cattctacta ttagtatggg gttttatcaa gcaattgtta
    10261 tctatcaccc gatttttatt cctaaacgat ctagctaaaa accttccttg gcttatagag
    10321 attgccccgt ttttctagaa tggctaacaa tttatcatct tcaaaggcag ccagttcttt
    10381 gtccgtttgg tctagctcaa taaaacgacc aaagcgaact tctgtagcct cttctggagt
    10441 taggaaaact ttgacaaggt cacctgtccc aatctctaaa ggatggagaa aatctaattg
    10501 cccagcctct actttttcag caatttcctc caaggtaaga gcatcttcta attgtaagcc
    10561 agcagcacta gtacgagtca aatgggacat atgagccgca taaccaagct tttcacccaa
    10621 atcaactgac aaagtacgga tgtaagtccc tttactgcat tttacacgaa aagtgaatcg
    10681 ggcaagttgg ccatcataag aaatcggact tgttcgctca aattgataaa tggtcacctg
    10741 acgttctgga cgctccactt cctgaccagc acgcgcatac tcatagagct tgcgaccatt
    10801 aaccttaact gccgaataca tagggggaat ctgagtaata ggcccagtca agctagcaat
    10861 cgcttcatca acaagctttt catccaaggg agacaaaaca ggggtttctg cgaccacttc
    10921 cccactagca tcctcagtcg tcgtggaata gcccagagtg atttccccct catagatctt
    10981 accctcgtcc tgcataaact cgaccatgcg tgtcgccttg ccaaccgcaa tcggcaaaac
    11041 acccaccaca tccggatcca aggttccacc atgaccaatt ttcttggttc ccaaaatctt
    11101 acgcagttta aaaaccgcat catgcgaggt cattcctgct tcctttttta agttaataat
    11161 accgttcatt tttgctttct actccccctt cagtgcttcg aacttcgctt tcattgttgg
    11221 atttttccgg gtcaattttt taacagagac atcttccaat ttgttgttag ctagacggag
    11281 ttggttttca gatgtggtca ggaatttctt aacctcttcc atgcgtttga tggccttgtc
    11341 gatttcatca atagcttttc caaagttagt cgaagctgaa ttatagttct tagcaaaagc
    11401 tagcttaaag gcatccaaat cttcctcaaa atgcgtaatg tcaatatttt gctcgcgaac
    11461 caaggccaac tcctgcttgt attttaggga atttagcgcc gcattacgta agagaccaat
    11521 caactggata aagaattgag gacgaacaac atacattttt tcatactcgt ggctgacgtc
    11581 aacaatccct gtgttaaagt agtcattatc ggcctcaagc atggtcacca aaacggcata
    11641 ctcacagttc ttctcccgac ggtccttgtc caattccttg taaaaatctg cattcttgtg
    11701 cttcttctct gttccgtccg cttcgttttt catctcaaac atgatagaaa tgatttcaac
    11761 tccattttca tcacactcac ggaagataaa gtccccttta gacccacgcg aagagacctt
    11821 gttatccttc tcaaagtaag catttggaaa ggcgaaacta cgaaccttgt taaactcact
    11881 ctctgcatac tgttctaggc tttccccaat cgcttttgta gattgttgag ccttaaaatt
    11941 cttataaaac tcgacttgtt cactagctgc tttaagctgg gcttcatagt tttgcttaac
    12001 agaagccaaa gacaactcat tttccttttc ttgcaagagg agctgatttt tgacctgatc
    12061 atgttctttt tctaggtcag aaagggtctt ttgcagttga ttttcatgct ccaaacgcaa
    12121 agtggccaat tggttctcca aatcctgtac ttccttgtcc ttagccaata aggcctgatg
    12181 gcttgtctgt tcaacttctt tcttggccaa ttctttttct gtatcaaagt tttggatctg
    12241 actctgtaat tgcgcaattt cttgatcctt ctgagccagt ttagtctgtt gctcattcat
    12301 agccttttgc tcagccaagg ccagttcctg cctcatccta tcgtgtagtt ccttatcaaa
    12361 ctctgccgtt ctcacttggg acaaaagttc agcatactgg ctttcattta ctgtaaagac
    12421 ttccccacag ttgggacatt tgatttcgtt cattacattc ctctttctag acttctgtaa
    12481 ccattatatc atgcatgaag gaaaatcaaa aacagcgagt cgaaaaccac tgtttatctt
    12541 ctttttcttt aaattttttc caaggccaag cgcaagtctt caatcaaatc atctacattt
    12601 tcaagtccga tagacaagtg gatttgattt ggtgtgacac ctgctgcttc taggtctttt
    12661 tctgacaatt gaccatgagt ggttgttgct ggatgaacaa caagagactt ggcatctgcc
    12721 acgttagcaa ggtctgagaa gatttccaaa ttatcaatga ccttgcgtgc ttcttcctcg
    12781 tcacctttga cgtggaaggt aaagattgaa ccgacacctt ttggcaagta tttctcagcc
    12841 aaggcataat aaggactatc tgcaagtttt ggataattta ccttttctac cttaggatgg
    12901 ttgacaagaa aatcaacaat tgtctcagca ttttgtacat ggcgttccac gcgaagtgaa
    12961 agggtttcaa gtctttgtag caagaggaaa gcattgaatg gtgacaaggc tgcacctgta
    13021 tcacgaagca attgaactcg aacagctata ataaaggcta ctgcacccac atcacgagta
    13081 tagctcaaat tgtggcagct tgaaccctcg tcaacaaatt gagggaattt ccctgaaggc
    13141 atccagtcaa aacgaccact atcgacaatt attcctccaa tagttgtacc atgcccaccg
    13201 ataaacttag tcgcagagtg aatggcaatg tcaacgccat gagagaagac gttaatcaaa
    13261 taaggtattg caaaagtatt gtctgacaca agtgggattt gatgtttatg agcaatctct
    13321 gccagttttt ccaggtctgg aatattaatc aaggagttac ccaaggtttc aatcaagaca
    13381 agcttggtat tgtctttgat agctgcttct acttcctcca aattatcaac atcgacaaag
    13441 gttgttgtga taccataacg aggaaggggt tctttcaaaa gattgaaggt tccaccgtaa
    13501 atagtcgaag cagccactac atggtcacca gcatgggcaa gcgccaaaat cgtataagtc
    13561 actgcagtca tacctgatgc tgttgctagc gcttcaacac caccttcaag ggcagctgtt
    13621 gtaggattgg tgatacgagt ataaatgttc cctggtttcc tcaaggcaaa cagatcggca
    13681 ccttcctacg tgtcatcaaa aacaaaaaat gttgtttgat aaatcggcac tgcacgagac
    13741 ttagtagctg gagccacaac ttgaccagca tgtagttgta gagtttcaga tttaaaatca
    13801 caagtcataa ggtgacctcc atatcatttt attaaggata ttgtagcacc ttgagttata
    13861 gtttacaaat atcagttttc tatattttga tataagaaat agctattacc ttattttgaa
    13921 aatgaaaaaa gcacgactca atcgtgctca ttttcttaat ctacataagt atcttcgttt
    13981 ttattgagga aggcatatgg aagacccatc aagaggcctc ctccgataaa gtttccgatg
    14041 aaagtcacac cccagtggcg aagcatattt ccaacaccga agttggcaat tgaatccgca
    14101 gcaacactga atttcacaat cgcgaaagaa gcaaagttcg ccgcaatgtg ctcgtttgtt
    14161 aagaatacaa acatgtaaat agctgacaac acaagccaaa gtttggcacc accatctttg
    14221 accaaaacaa atgaaagaat ggcaatgttt acaaagatat tggctaaaat accttcaagt
    14281 aagactaact cattggaacg acctaacttc atctctacaa cacctgagat gaaactatcg
    14341 tgtgtcagat tcgcataggc tgccgaatga gcaaagcccc accctgctat caaggctccg
    14401 ataaggttga acaaggtaca gtatagtaaa atctcagctg tttttctcca agagattttt
    14461 tttaagaaac taccagcagt caagaacatc atgtttgaag tgaccaactc ggcattcaaa
    14521 aaaacaatgt aggccaagcc ccaagcaaaa acgaatggaa agaggaagcg tccactacct
    14581 ggtgcaattt tattaatcaa gtcagcccca actgcacctg cagcagtact gaaggttaaa
    14641 aatgcacctg cgaacatcga acgaatcgca tacttaaatt tgctttgact ataaagactt
    14701 tctttcttat tacaagcaaa ttcaatcttt gaaataaatt ctgaagaaac cataataaac
    14761 tcctaaatct tttttcttga taattatatc acaaacttta gattttagga agcgttttct
    14821 gtatttcata aaagtttata gtagattgaa actagaatag tacacctcta cttctaaaac
    14881 attgttagaa atcgatttga ctgtcctgaa cgattcgtcc tattcttatt tcattttact
    14941 atatttttat gaaaatctta aaaaatcagt gaaatccatg atttcactga tttgtattaa
    15001 taaaattgtt tatatggttg attgaaagct gttaggattt cattagatgt ttgtgaataa
    15061 tcttttgttt ctttcaaatc acctttgaca ataatacgtt ctgtagcagc aaggtcttca
    15121 caggttacta atgtgatttc attgacccca tctctatcat caacttcatc aacacgatcc
    15181 ggtgccacac gtttgacttc acgtatttca taagtataaa ctttattttt atcggttaga
    15241 taaatcttca tgccattttt agcattatct aaaggagaaa ataacatttt attagcatta
    15301 tcaacaccaa agatatggtg actagctaga ctataatttc cttctcccat tacttgctcg
    15361 cgtttcattg taccagctcc gtagaagaga ttaacattat caagtccttt aaaaatcggc
    15421 aaattcattt ccaattcagg aattgcaatt cccccaataa ctggtaattt ttgagcatcc
    15481 cattgagaag ttagaacagc ttccgaagag atagctttga cagaatcaaa gtcaaaattg
    15541 ccttctgtat cctgattttc ttctaatttt tcttttgata cctggctaac ttgatactta
    15601 ttggtattcc agactatgaa aatatttcga atttgagtat taaaaatcaa agccagtgac
    15661 agtaatatca gaaatcctgc taggatattt gtcagcagat tttttcgctt gtttttcttt
    15721 ttattatttt tttgagacat tatgcttcac cttctgtttc gttttctgtc ccaacttctt
    15781 ctttttctgc caccgcaacc gttgtgaaag tcactatctg agcatcttga tccaggcgca
    15841 ttactttaac tcccatagtt gcacgtcctg tttgtgaaat attggcaaga ttggttcgaa
    15901 tcatgacacc tgtatcagtg ataatcatca aatcctcatt cccttgaaca gtcataagac
    15961 cggccagcaa gccatttttt tcggtaattt tagctgtctg cattccctta ccaccacgac
    16021 cttttgttgg gtattcagta gcgactgtac gcttaccata tcctttttct gtgataataa
    16081 gaacctcatc ttgatcagta atcaagctgg caccaacaac tgtgtctcct tcacgaaggt
    16141 taacaccttt cacaccagtg gcgatacggc tcataccacg aacggctgat tgattaaagc
    16201 gaactgcata accaaacttg gtaccaatga taatatccat atctccttct gccaacaaga
    16261 cattgattaa ctcatcttca tcctttaaat tcagcgcttt gagaccattt tgacgaatat
    16321 tggcaaactc cttaacacta gttctcttca caataccgtg acgggttgta aagaagagat
    16381 aagcatcatc actgcgatca gactcaacat tgataaccgt ctgaatactt tcgtcttcat
    16441 ccaatttcaa gagattgact actggtagcc ctttggcagt ccgaccatac tcaggaattt
    16501 cataaccttt aagacgatag acacgtccct tgtttgtgaa gaagagcaga tgatcatggg
    16561 tactagttga cactaactca cgaacaaagt catcatcttt cactcccgtt ccttggacac
    16621 cacgaccccc acgtttttga gcagtgaact cgtcctgatc caaacgctta atgtagcctc
    16681 tgttagaaag ggtaatcaag acatccgatt cttcaatcaa gtcctcatcc tcgagactca
    16741 agacctgtcc aaccatcaac tctgtacggc gtttatcaga aaatttacgt ttaacttcat
    16801 ccaattcgtc tttgataatt tgagaaacac gttcaggctt agcaagaata tctgctaaat
    16861 ccgcaatcag agccaagagg tcatcatact cagattgaat cttatcgcgt tccaaacctg
    16921 tcaaacgacg aagacgcata tcaaggatag cttgactttg acgttcagaa agcttaaact
    16981 tgctcatcaa ctcagcttga gcttccgcat ccgtttcact agcacggatg atacgaatca
    17041 cttcgtcgat atggtctagc gcaatcaaga gaccttctaa gatatgagcg cgcgcttccg
    17101 ctttttcctt atcaaaacgt gtacgacgaa caaccacttc tttttggtgc tcgatataag
    17161 catccaaaat ctgacgaaga gacaaaattt tcggtatacc attttggata gcgagcatat
    17221 tgaaaccaaa attggtttgc atttgggtca ttttgaagag gttattgaga ataacattgg
    17281 ctgaggcgtc gcgcttgact tcaataacaa atcgaacacc ttcacggttt gactcatcac
    17341 gtactgc
//
